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Volumn 30, Issue 1-3, 1998, Pages 97-113

Polylysine-based transfection systems utilizing receptor-mediated delivery

Author keywords

DNA condensation; Endosomal release; In vitro; In vivo; Nuclear trafficking; Polylysine; Receptor mediated gene transfer

Indexed keywords

BIOSYNTHESIS; CELLS; CONDENSATION; DNA; DRUG PRODUCTS; GENES; GENETIC ENGINEERING; PROTEINS;

EID: 0032473410     PISSN: 0169409X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0169-409X(97)00110-5     Document Type: Review
Times cited : (496)

References (157)
  • 1
    • 0030065393 scopus 로고    scopus 로고
    • An array of murine leukemia virus-related elements is transmitted and expressed in a primate recipient of retroviral gene transfer
    • Purcell D.F., Broscius C.M., Vanin E.F., Buckler C.E., Nienhuis A.W., Martin M.A. An array of murine leukemia virus-related elements is transmitted and expressed in a primate recipient of retroviral gene transfer. J. Virol. 70:1996;887-897.
    • (1996) J. Virol. , vol.70 , pp. 887-897
    • Purcell, D.F.1    Broscius, C.M.2    Vanin, E.F.3    Buckler, C.E.4    Nienhuis, A.W.5    Martin, M.A.6
  • 2
    • 0028801333 scopus 로고
    • Genetic rearrangements occuring during a single cycle of murine leukemia virus vector replication: Characterization and implications
    • Parthasarathi S., Varela Echavarria A., Ron Y., Preston B.D., Dougherty J.P. Genetic rearrangements occuring during a single cycle of murine leukemia virus vector replication: characterization and implications. J. Virol. 69:1995;7991-8000.
    • (1995) J. Virol. , vol.69 , pp. 7991-8000
    • Parthasarathi, S.1    Varela Echavarria, A.2    Ron, Y.3    Preston, B.D.4    Dougherty, J.P.5
  • 3
    • 15444367562 scopus 로고
    • The vector void in gene therapy
    • Hodgson C.P. The vector void in gene therapy. Bio/Technology. 13:1995;222-225.
    • (1995) Bio/Technology , vol.13 , pp. 222-225
    • Hodgson, C.P.1
  • 4
    • 0028170358 scopus 로고
    • Multicompartment, numerical model of cellular events in the pharmacokinetics of gene therapies
    • Ledley T.S., Ledley F.D. Multicompartment, numerical model of cellular events in the pharmacokinetics of gene therapies. Hum. Gene Ther. 5:1994;679-691.
    • (1994) Hum. Gene Ther. , vol.5 , pp. 679-691
    • Ledley, T.S.1    Ledley, F.D.2
  • 5
    • 0028789294 scopus 로고
    • High efficiency of animal cell DNA transfection using poly-L-ornithine in optimized conditions
    • Lemnaouar M., Cajero-Juarez M., Houdebine L.-M. High efficiency of animal cell DNA transfection using poly-L-ornithine in optimized conditions. Transgenics. 1:1995;671-677.
    • (1995) Transgenics , vol.1 , pp. 671-677
    • Lemnaouar, M.1    Cajero-Juarez, M.2    Houdebine, L.-M.3
  • 6
    • 0030067493 scopus 로고    scopus 로고
    • Transient gene transfer into myotubes following differentiation in culture
    • Brooks Robey R., Osawa H., Printz R.L., Granner D.K. Transient gene transfer into myotubes following differentiation in culture. Biotechniques. 20:1996;40-42.
    • (1996) Biotechniques , vol.20 , pp. 40-42
    • Brooks Robey, R.1    Osawa, H.2    Printz, R.L.3    Granner, D.K.4
  • 7
    • 0027168695 scopus 로고
    • Efficient DNA transfection of quiescent mammalian cells using poly-L-ornithine
    • Dong Y., Skoultchi A.I., Pollard J.W. Efficient DNA transfection of quiescent mammalian cells using poly-L-ornithine. Nucleic Acids Res. 21:1993;771-772.
    • (1993) Nucleic Acids Res. , vol.21 , pp. 771-772
    • Dong, Y.1    Skoultchi, A.I.2    Pollard, J.W.3
  • 8
    • 0028168773 scopus 로고
    • Galactosylated histone-mediated gene transfer and expression
    • Chen J., Stickles R.J., Daichendt K.A. Galactosylated histone-mediated gene transfer and expression. Hum. Gene Ther. 5:1994;429-435.
    • (1994) Hum. Gene Ther. , vol.5 , pp. 429-435
    • Chen, J.1    Stickles, R.J.2    Daichendt, K.A.3
  • 9
    • 0025891831 scopus 로고
    • Transferrin-polycation-DNA complexes: The effect of polycations on the structure of the complexes and DNA delivery to the cells
    • Wagner E., Cotten M., Foisner R., Birnstiel M.L. Transferrin-polycation-DNA complexes: The effect of polycations on the structure of the complexes and DNA delivery to the cells. Proc. Natl. Acad. Sci. U.S.A. 88:1991;4255-4259.
    • (1991) Proc. Natl. Acad. Sci. U.S.A. , vol.88 , pp. 4255-4259
    • Wagner, E.1    Cotten, M.2    Foisner, R.3    Birnstiel, M.L.4
  • 10
    • 0029836074 scopus 로고    scopus 로고
    • Gene transfer into mammalian cells using histone-condensed plasmid DNA
    • Fritz J.D., Herweijer H., Zhang G., Wolff J.A. Gene transfer into mammalian cells using histone-condensed plasmid DNA. Hum. Gene Ther. 7:1996;1395-1404.
    • (1996) Hum. Gene Ther. , vol.7 , pp. 1395-1404
    • Fritz, J.D.1    Herweijer, H.2    Zhang, G.3    Wolff, J.A.4
  • 11
    • 0021770787 scopus 로고
    • High level transient expression of a chloramphenicol acetyl transferase gene by DEAE-dextran mediated DNA transfection coupled with a dimethyl sulfoxide or glycerol shock treatment
    • Lopata M.L., Cleveland D.W., Sollner-Webb B. High level transient expression of a chloramphenicol acetyl transferase gene by DEAE-dextran mediated DNA transfection coupled with a dimethyl sulfoxide or glycerol shock treatment. Nucleic Acids Res. 12:1984;5707-5717.
    • (1984) Nucleic Acids Res. , vol.12 , pp. 5707-5717
    • Lopata, M.L.1    Cleveland, D.W.2    Sollner-Webb, B.3
  • 12
    • 0025947392 scopus 로고
    • Transfection of adherent murine peritoneal macrophages with a reporter gene using DEAE-dextran
    • Rupprecht A.P., Coleman D.L. Transfection of adherent murine peritoneal macrophages with a reporter gene using DEAE-dextran. J. Immunol. Methods. 144:1991;157-163.
    • (1991) J. Immunol. Methods , vol.144 , pp. 157-163
    • Rupprecht, A.P.1    Coleman, D.L.2
  • 13
    • 0026075563 scopus 로고
    • Comparison of methods for transfection of human epidermal keratinocytes
    • Jiang C.-K., Connolly D., Blumenberg M. Comparison of methods for transfection of human epidermal keratinocytes. J. Invest. Dermatol. 97:1991;969-973.
    • (1991) J. Invest. Dermatol. , vol.97 , pp. 969-973
    • Jiang, C.-K.1    Connolly, D.2    Blumenberg, M.3
  • 15
    • 0029160083 scopus 로고
    • A novel, versatile vector for gene and oligonucleotide transfer into cells in culture and in vivo: Polyethyleneimine
    • Boussif O., Lezoualc'h F., Zanta M.A.et al. A novel, versatile vector for gene and oligonucleotide transfer into cells in culture and in vivo: polyethyleneimine. Proc. Natl. Acad. Sci. U.S.A. 92:1995;7297-7301.
    • (1995) Proc. Natl. Acad. Sci. U.S.A. , vol.92 , pp. 7297-7301
    • Boussif, O.1    Lezoualc'h, F.2    Zanta, M.A.3
  • 16
    • 0027655718 scopus 로고
    • Polyamidoamine cascade polymers mediate efficient transfection of cells in culture
    • Haensler J., Szoka F.C. Polyamidoamine cascade polymers mediate efficient transfection of cells in culture. Bioconjugate Chem. 4:1993;372-379.
    • (1993) Bioconjugate Chem. , vol.4 , pp. 372-379
    • Haensler, J.1    Szoka, F.C.2
  • 18
    • 0029744235 scopus 로고    scopus 로고
    • Effect of size and serum proteins on transfection efficiency of poly((2-dimethylamino)ethyl methacrylate)-plasmid nanoparticles
    • Cherng J.-Y., van de Wetering P., Talsma H., Crommelin D.J.A., Hennink W.E. Effect of size and serum proteins on transfection efficiency of poly((2-dimethylamino)ethyl methacrylate)-plasmid nanoparticles. Pharm. Res. 13:1996;1038-1042.
    • (1996) Pharm. Res. , vol.13 , pp. 1038-1042
    • Cherng, J.-Y.1    Van De Wetering, P.2    Talsma, H.3    Crommelin, D.J.A.4    Hennink, W.E.5
  • 19
    • 0028414109 scopus 로고
    • Glycoconjugates as carriers for specific delivery of therapeutic drugs and genes
    • Monsigny M., Roche A.C., Midoux P., Mayer R. Glycoconjugates as carriers for specific delivery of therapeutic drugs and genes. Adv. Drug Deliv. Rev. 14:1994;1-24.
    • (1994) Adv. Drug Deliv. Rev. , vol.14 , pp. 1-24
    • Monsigny, M.1    Roche, A.C.2    Midoux, P.3    Mayer, R.4
  • 20
    • 0028417374 scopus 로고
    • Targeting of genes to the liver with glycoprotein carriers
    • Frese J., Wu C.H., Wu G.Y. Targeting of genes to the liver with glycoprotein carriers. Adv. Drug Deliv. Rev. 14:1994;137-152.
    • (1994) Adv. Drug Deliv. Rev. , vol.14 , pp. 137-152
    • Frese, J.1    Wu, C.H.2    Wu, G.Y.3
  • 21
    • 0028079888 scopus 로고
    • An evaluation of receptor-mediated gene transfer using synthetic DNA-ligand complexes
    • Perales J.C., Ferkol T., Molas M., Hanson R.W. An evaluation of receptor-mediated gene transfer using synthetic DNA-ligand complexes. Eur. J. Biochem. 226:1994;255-266.
    • (1994) Eur. J. Biochem. , vol.226 , pp. 255-266
    • Perales, J.C.1    Ferkol, T.2    Molas, M.3    Hanson, R.W.4
  • 22
    • 0029136052 scopus 로고
    • DNA complexes with polycations for the delivery of genetic material into cells
    • Kabanov A.V., Kabanov V.A. DNA complexes with polycations for the delivery of genetic material into cells. Bioconjugate Chem. 6:1995;7-20.
    • (1995) Bioconjugate Chem. , vol.6 , pp. 7-20
    • Kabanov, A.V.1    Kabanov, V.A.2
  • 23
    • 0028464351 scopus 로고
    • Strategies to achieve targeted gene delivery via the receptor-mediated endocytosis pathway
    • Michael S.I., Curiel D.T. Strategies to achieve targeted gene delivery via the receptor-mediated endocytosis pathway. Gene Ther. 1:1994;223-232.
    • (1994) Gene Ther. , vol.1 , pp. 223-232
    • Michael, S.I.1    Curiel, D.T.2
  • 24
    • 0029687654 scopus 로고    scopus 로고
    • Strategies to accomplish gene delivery via the receptor-mediated pathway
    • Cristiano R.J., Curiel D.T. Strategies to accomplish gene delivery via the receptor-mediated pathway. Cancer Gene Ther. 3:1996;49-57.
    • (1996) Cancer Gene Ther. , vol.3 , pp. 49-57
    • Cristiano, R.J.1    Curiel, D.T.2
  • 25
    • 0028879807 scopus 로고
    • Molecular conjugates: A targeted gene delivery vector for molecular medicine
    • Cristiano R.J., Roth J.A. Molecular conjugates: a targeted gene delivery vector for molecular medicine. J. Mol. Med. 73:1995;479-486.
    • (1995) J. Mol. Med. , vol.73 , pp. 479-486
    • Cristiano, R.J.1    Roth, J.A.2
  • 26
    • 0029147628 scopus 로고
    • Nonviral gene therapy: The promise of genes as pharmaceutical products
    • Ledley F.D. Nonviral gene therapy: the promise of genes as pharmaceutical products. Hum. Gene Ther. 6:1995;1129-1144.
    • (1995) Hum. Gene Ther. , vol.6 , pp. 1129-1144
    • Ledley, F.D.1
  • 27
    • 0027314591 scopus 로고
    • Targeted delivery of DNA for gene therapy via receptors
    • Findeis M.A., Merwin J.R., Spitalny G.L., Chiou H.C. Targeted delivery of DNA for gene therapy via receptors. Tibtech. 11:1993;202-205.
    • (1993) Tibtech , vol.11 , pp. 202-205
    • Findeis, M.A.1    Merwin, J.R.2    Spitalny, G.L.3    Chiou, H.C.4
  • 28
    • 0028673154 scopus 로고
    • Ligand-based carrier systems for delivery of DNA to hepatocytes
    • Findeis M.A., Wu C.H., Wu G.Y. Ligand-based carrier systems for delivery of DNA to hepatocytes. Methods Enzymol. 247:1994;341-351.
    • (1994) Methods Enzymol. , vol.247 , pp. 341-351
    • Findeis, M.A.1    Wu, C.H.2    Wu, G.Y.3
  • 29
    • 0028416238 scopus 로고
    • Delivery of drugs, proteins and genes into cells using transferrin as a ligand for receptor-mediated endocytosis
    • Wagner E., Curiel D., Cotten M. Delivery of drugs, proteins and genes into cells using transferrin as a ligand for receptor-mediated endocytosis. Adv. Drug Deliv. Rev. 14:1994;113-135.
    • (1994) Adv. Drug Deliv. Rev. , vol.14 , pp. 113-135
    • Wagner, E.1    Curiel, D.2    Cotten, M.3
  • 30
    • 0027297678 scopus 로고
    • Receptor mediated transport of DNA into eukaryotic cells
    • Cotten M., Wagner E., Birnstiel M.L. Receptor mediated transport of DNA into eukaryotic cells. Methods Enzymol. 217:1993;618-644.
    • (1993) Methods Enzymol. , vol.217 , pp. 618-644
    • Cotten, M.1    Wagner, E.2    Birnstiel, M.L.3
  • 31
    • 0027137837 scopus 로고
    • Non-viral approaches to gene therapy
    • Cotten M., Wagner E. Non-viral approaches to gene therapy. Curr. Opin. Biotechnol. 4:1993;705-710.
    • (1993) Curr. Opin. Biotechnol. , vol.4 , pp. 705-710
    • Cotten, M.1    Wagner, E.2
  • 32
    • 0019852693 scopus 로고
    • Poly(L-lysine) has different membrane transport and drug-carrier properties when complexed with heparin
    • Shen W.-C., Ryser H.J.-P. Poly(L-lysine) has different membrane transport and drug-carrier properties when complexed with heparin. Proc. Natl. Acad. Sci. U.S.A. 78:1981;7589-7593.
    • (1981) Proc. Natl. Acad. Sci. U.S.A. , vol.78 , pp. 7589-7593
    • Shen, W.-C.1    Ryser, H.J.-P.2
  • 33
    • 0021891364 scopus 로고
    • Polylysine-drug conjugates
    • Arnold L.J. Polylysine-drug conjugates. Methods Enzymol. 112:1985;270-285.
    • (1985) Methods Enzymol. , vol.112 , pp. 270-285
    • Arnold, L.J.1
  • 34
    • 0028934457 scopus 로고
    • Carbamylation decreases the cytotoxicity but not the drug-carrier properties of polylysine
    • Ekrami H.M., Shen W.C. Carbamylation decreases the cytotoxicity but not the drug-carrier properties of polylysine. J. Drug Target. 2:1995;469-475.
    • (1995) J. Drug Target. , vol.2 , pp. 469-475
    • Ekrami, H.M.1    Shen, W.C.2
  • 35
    • 0026757191 scopus 로고
    • Drug-polymer conjugates: Potential for improved chemotherapy
    • Duncan R. Drug-polymer conjugates: potential for improved chemotherapy. Anti-Cancer Drugs. 3:1992;175-210.
    • (1992) Anti-Cancer Drugs , vol.3 , pp. 175-210
    • Duncan, R.1
  • 36
    • 0000564128 scopus 로고
    • Characterization of DNA condensates induced by poly(ethylene oxide) and polylysine
    • Laemmli U.K. Characterization of DNA condensates induced by poly(ethylene oxide) and polylysine. Proc. Natl. Acad. Sci. U.S.A. 72:1975;4288-4292.
    • (1975) Proc. Natl. Acad. Sci. U.S.A. , vol.72 , pp. 4288-4292
    • Laemmli, U.K.1
  • 37
    • 0025215891 scopus 로고
    • Chiral and structural discrimination in binding of polypeptides with condensed nucleic acid structures
    • Reich Z., Ittah Y., Weinberger S., Minsky A. Chiral and structural discrimination in binding of polypeptides with condensed nucleic acid structures. J. Biol. Chem. 265:1990;5590-5594.
    • (1990) J. Biol. Chem. , vol.265 , pp. 5590-5594
    • Reich, Z.1    Ittah, Y.2    Weinberger, S.3    Minsky, A.4
  • 38
    • 0014556033 scopus 로고
    • Deoxyribonucleic acid-polylysine complexes. Structure and nucleotide specificity
    • Shapiro J.T., Leng M., Felsenfeld G. Deoxyribonucleic acid-polylysine complexes. Structure and nucleotide specificity. Biochemistry. 8:1969;3219-3232.
    • (1969) Biochemistry , vol.8 , pp. 3219-3232
    • Shapiro, J.T.1    Leng, M.2    Felsenfeld, G.3
  • 39
    • 0019872606 scopus 로고
    • ε-trimethyllysine) and polylysine with polynucleotides: Circular dichroism and A-T sequence selectivity
    • ε-trimethyllysine) and polylysine with polynucleotides: circular dichroism and A-T sequence selectivity. Biochemistry. 20:1981;4761-4765.
    • (1981) Biochemistry , vol.20 , pp. 4761-4765
    • Granados, E.N.1    Bello, J.2
  • 40
    • 0015791256 scopus 로고
    • Conformational studies of nucleoprotein. Circular dichroism of deoxyribonucleic acid base pairs bound by polylysine
    • Chang C., Weiskopf M., Li H.J. Conformational studies of nucleoprotein. Circular dichroism of deoxyribonucleic acid base pairs bound by polylysine. Biochemistry. 12:1973;3028-3032.
    • (1973) Biochemistry , vol.12 , pp. 3028-3032
    • Chang, C.1    Weiskopf, M.2    Li, H.J.3
  • 41
    • 0023646692 scopus 로고
    • Electron microscopy and biochemical properties of polyamine-compacted DNA
    • Baeza I., Gariglio P., Rangel L.M.et al. Electron microscopy and biochemical properties of polyamine-compacted DNA. Biochemistry. 26:1987;6387-6392.
    • (1987) Biochemistry , vol.26 , pp. 6387-6392
    • Baeza, I.1    Gariglio, P.2    Rangel, L.M.3
  • 42
    • 0026487591 scopus 로고
    • A brief survey of methods for preparing protein conjugates with dyes, haptens, and cross-linking agents
    • Brinkley M. A brief survey of methods for preparing protein conjugates with dyes, haptens, and cross-linking agents. Bioconjugate Chem. 3:1992;2-13.
    • (1992) Bioconjugate Chem. , vol.3 , pp. 2-13
    • Brinkley, M.1
  • 45
    • 0025235971 scopus 로고
    • Chemical modifications of proteins: History and applications
    • Means G.E., Feeney R.E. Chemical modifications of proteins: history and applications. Bioconjugate Chem. 1:1990;2-12.
    • (1990) Bioconjugate Chem. , vol.1 , pp. 2-12
    • Means, G.E.1    Feeney, R.E.2
  • 47
    • 0026891048 scopus 로고
    • Use of N-terminal modified poly(L-lysine)-antibody conjugate as a carrier for targeted gene delivery in mouse lung endothelial cells
    • Trubetskoy V.S., Torchilin V.P., Kennel S.J., Huang L. Use of N-terminal modified poly(L-lysine)-antibody conjugate as a carrier for targeted gene delivery in mouse lung endothelial cells. Bioconjugate Chem. 3:1992;323-327.
    • (1992) Bioconjugate Chem. , vol.3 , pp. 323-327
    • Trubetskoy, V.S.1    Torchilin, V.P.2    Kennel, S.J.3    Huang, L.4
  • 50
    • 0028223310 scopus 로고
    • Gene transfer in vivo: Sustained expression and regulation of genes introduced into the liver by receptor-targeted uptake
    • Perales J.C., Ferkol T., Beegen H., Ratnoff O.D., Hanson R.W. Gene transfer in vivo: sustained expression and regulation of genes introduced into the liver by receptor-targeted uptake. Proc. Natl. Acad. Sci. U.S.A. 91:1994;4086-4090.
    • (1994) Proc. Natl. Acad. Sci. U.S.A. , vol.91 , pp. 4086-4090
    • Perales, J.C.1    Ferkol, T.2    Beegen, H.3    Ratnoff, O.D.4    Hanson, R.W.5
  • 51
    • 0030003605 scopus 로고    scopus 로고
    • Gene transfer by DNA/glycosylated polylysine complexes into human blood monocyte-derived macrophages
    • Erbacher P., Bousser M.-T., Raimond J., Monsigny M., Midoux P., Roche A.C. Gene transfer by DNA/glycosylated polylysine complexes into human blood monocyte-derived macrophages. Hum. Gene Ther. 7:1996;721-729.
    • (1996) Hum. Gene Ther. , vol.7 , pp. 721-729
    • Erbacher, P.1    Bousser, M.-T.2    Raimond, J.3    Monsigny, M.4    Midoux, P.5    Roche, A.C.6
  • 52
    • 0027217646 scopus 로고
    • Specific gene transfer mediated by lactosylated poly-L-lysine into hepatoma cells
    • Midoux P., Mendes C., Legrand A.et al. Specific gene transfer mediated by lactosylated poly-L-lysine into hepatoma cells. Nucleic Acids Res. 21:1993;871-878.
    • (1993) Nucleic Acids Res. , vol.21 , pp. 871-878
    • Midoux, P.1    Mendes, C.2    Legrand, A.3
  • 53
    • 0029328597 scopus 로고
    • Glycosylated polylysine/DNA complexes: Gene transfer efficiency in relation with the size and the sugar substitution level of glycosylated polylysines and with the plasmid size
    • Erbacher P., Roche A.C., Monsigny M., Midoux P. Glycosylated polylysine/DNA complexes: gene transfer efficiency in relation with the size and the sugar substitution level of glycosylated polylysines and with the plasmid size. Bioconjugate Chem. 6:1995;401-410.
    • (1995) Bioconjugate Chem. , vol.6 , pp. 401-410
    • Erbacher, P.1    Roche, A.C.2    Monsigny, M.3    Midoux, P.4
  • 54
    • 0029761475 scopus 로고    scopus 로고
    • Gluconoylated and glycosylated polylysines as vectors for gene transfer into cystic fibrosis airway epithelial cells
    • Kollen W.J.W., Midoux P., Erbacher P.et al. Gluconoylated and glycosylated polylysines as vectors for gene transfer into cystic fibrosis airway epithelial cells. Hum. Gene Ther. 7:1996;1577-1586.
    • (1996) Hum. Gene Ther. , vol.7 , pp. 1577-1586
    • Kollen, W.J.W.1    Midoux, P.2    Erbacher, P.3
  • 55
    • 0029941321 scopus 로고    scopus 로고
    • A novel DNA-peptide complex for efficient gene transfer and expression in mammalian cells
    • Gottschalk S., Sparrow J.T., Hauer J.et al. A novel DNA-peptide complex for efficient gene transfer and expression in mammalian cells. Gene Ther. 3:1996;448-457.
    • (1996) Gene Ther. , vol.3 , pp. 448-457
    • Gottschalk, S.1    Sparrow, J.T.2    Hauer, J.3
  • 56
    • 0002881691 scopus 로고    scopus 로고
    • Advances in receptor-mediated gene transfer into cells in vitro and in vivo
    • P.L. Felgner, M.J. Heller, P. Lehn, J.P. Behr, F.C. Szoka (Eds.), Cambridge Healthtech Institute, Newton Upper Falls, MA
    • J.C. Perales, M. Molas, R.W. Hanson, Advances in receptor-mediated gene transfer into cells in vitro and in vivo, in: Artificial Self-assembling Systems for Gene Delivery, P.L. Felgner, M.J. Heller, P. Lehn, J.P. Behr, F.C. Szoka (Eds.), Cambridge Healthtech Institute, Newton Upper Falls, MA, 1996, pp. 105-119.
    • (1996) Artificial Self-assembling Systems for Gene Delivery , pp. 105-119
    • Perales, J.C.1    Molas, M.2    Hanson, R.W.3
  • 57
    • 0030005946 scopus 로고    scopus 로고
    • Atomic force microscopic analysis of the influence of the molecular weight of poly-L-lysine on the size of polyelectrolyte complexes formed with DNA
    • Wolfert M.A., Seymour L.W. Atomic force microscopic analysis of the influence of the molecular weight of poly-L-lysine on the size of polyelectrolyte complexes formed with DNA. Gene Ther. 3:1996;269-273.
    • (1996) Gene Ther. , vol.3 , pp. 269-273
    • Wolfert, M.A.1    Seymour, L.W.2
  • 58
    • 0025313130 scopus 로고
    • Transferrin-polycation-mediated introduction of DNA into human leukemic cells: Stimulation by agents that affect the survival of transfected DNA or modulate transferrin receptor levels
    • Cotten M., Längle-Rouault F., Kirlappos H.et al. Transferrin-polycation-mediated introduction of DNA into human leukemic cells: stimulation by agents that affect the survival of transfected DNA or modulate transferrin receptor levels. Proc. Natl. Acad. Sci. U.S.A. 87:1990;4033-4037.
    • (1990) Proc. Natl. Acad. Sci. U.S.A. , vol.87 , pp. 4033-4037
    • Cotten, M.1    Längle-Rouault, F.2    Kirlappos, H.3
  • 59
    • 0026315433 scopus 로고
    • Receptor-mediated gene delivery in vivo. Partial correction of genetic analbumenia in Nagase rats
    • Wu G.Y., Wilson J.M., Shalaby F., Grossman M., Shafritz D.A., Wu C.H. Receptor-mediated gene delivery in vivo. Partial correction of genetic analbumenia in Nagase rats. J. Biol. Chem. 266:1991;14338-14342.
    • (1991) J. Biol. Chem. , vol.266 , pp. 14338-14342
    • Wu, G.Y.1    Wilson, J.M.2    Shalaby, F.3    Grossman, M.4    Shafritz, D.A.5    Wu, C.H.6
  • 60
    • 0024343077 scopus 로고
    • Targeting genes: Delivery and persistent expression of a foreign gene driven by mammalian regulatory elements in vivo
    • Wu G.Y., Wilson J.M., Wu C.H. Targeting genes: delivery and persistent expression of a foreign gene driven by mammalian regulatory elements in vivo. J. Biol. Chem. 264:1989;16985-16987.
    • (1989) J. Biol. Chem. , vol.264 , pp. 16985-16987
    • Wu, G.Y.1    Wilson, J.M.2    Wu, C.H.3
  • 61
    • 0028799484 scopus 로고
    • Gene transfer into the airway epithelium of animals by targeting the polymeric immunoglobulin receptor
    • Ferkol T., Perales J.C., Eckman E., Kaetzel C.S., Hanson R.W., Davis P. Gene transfer into the airway epithelium of animals by targeting the polymeric immunoglobulin receptor. J. Clin. Invest. 95:1995;493-502.
    • (1995) J. Clin. Invest. , vol.95 , pp. 493-502
    • Ferkol, T.1    Perales, J.C.2    Eckman, E.3    Kaetzel, C.S.4    Hanson, R.W.5    Davis, P.6
  • 62
    • 0028618172 scopus 로고
    • Enhanced resistance to nuclease degradation of nucleic acids complexed to asialoglycoprotein-polylysine carriers
    • Chiou H.C., Tangco M.V., Levine S.M.et al. Enhanced resistance to nuclease degradation of nucleic acids complexed to asialoglycoprotein-polylysine carriers. Nucleic Acids Res. 22:1994;5439-5446.
    • (1994) Nucleic Acids Res. , vol.22 , pp. 5439-5446
    • Chiou, H.C.1    Tangco, M.V.2    Levine, S.M.3
  • 64
    • 0021247676 scopus 로고
    • Polycations as prostaglandin synthesis inducers. Stimulation of arachidonic acid release and prostaglandin synthesis in cultured fibroblasts by poly(L-lysine) and other synthetic polycations
    • Shier W.T., Dubourdieu D.J., Durkin J.P. Polycations as prostaglandin synthesis inducers. Stimulation of arachidonic acid release and prostaglandin synthesis in cultured fibroblasts by poly(L-lysine) and other synthetic polycations. Biochim. Biophys. Acta. 793:1984;238-250.
    • (1984) Biochim. Biophys. Acta , vol.793 , pp. 238-250
    • Shier, W.T.1    Dubourdieu, D.J.2    Durkin, J.P.3
  • 65
    • 0010626572 scopus 로고
    • Effect of polylysine on the leakage and retention of compounds by Ehrlich ascites tumor cells
    • Kornguth S.E., Stahmann M.A. Effect of polylysine on the leakage and retention of compounds by Ehrlich ascites tumor cells. Cancer Res. 21:1961;907-912.
    • (1961) Cancer Res. , vol.21 , pp. 907-912
    • Kornguth, S.E.1    Stahmann, M.A.2
  • 66
    • 0019405715 scopus 로고
    • The effect of added H1 histone and polylysine on DNA synthesis and cell division of cultured mammalian cells
    • Kundahl E., Richman R., Flickinger R.A. The effect of added H1 histone and polylysine on DNA synthesis and cell division of cultured mammalian cells. J. Cell. Physiol. 108:1981;291-298.
    • (1981) J. Cell. Physiol. , vol.108 , pp. 291-298
    • Kundahl, E.1    Richman, R.2    Flickinger, R.A.3
  • 67
    • 0024997935 scopus 로고
    • Pp54 Microtubule-associated protein 2 kinase
    • Kyriakis J.M., Avruch J. pp54 Microtubule-associated protein 2 kinase. J. Biol. Chem. 265:1990;17355-17363.
    • (1990) J. Biol. Chem. , vol.265 , pp. 17355-17363
    • Kyriakis, J.M.1    Avruch, J.2
  • 68
    • 0020490949 scopus 로고
    • Polycation-induced fusion of negatively-charged vesicles
    • Gad A.E., Silver B.L., Eytan G.D. Polycation-induced fusion of negatively-charged vesicles. Biochim. Biophys. Acta. 690:1982;124-132.
    • (1982) Biochim. Biophys. Acta , vol.690 , pp. 124-132
    • Gad, A.E.1    Silver, B.L.2    Eytan, G.D.3
  • 69
    • 0022368625 scopus 로고
    • Promotion and inhibition of vesicle fusion by polylysine
    • Gad A.E., Bental M., Elyashiv G., Weinberg H. Promotion and inhibition of vesicle fusion by polylysine. Biochemistry. 24:1985;6277-6282.
    • (1985) Biochemistry , vol.24 , pp. 6277-6282
    • Gad, A.E.1    Bental, M.2    Elyashiv, G.3    Weinberg, H.4
  • 70
    • 0023045569 scopus 로고
    • Polylysine induces pH-dependent fusion of acidic phospholipid vesicles: A model for polycation-induced fusion
    • Walter A., Steer C.J., Blumenthal R. Polylysine induces pH-dependent fusion of acidic phospholipid vesicles: a model for polycation-induced fusion. Biochim. Biophys. Acta. 861:1986;319-330.
    • (1986) Biochim. Biophys. Acta , vol.861 , pp. 319-330
    • Walter, A.1    Steer, C.J.2    Blumenthal, R.3
  • 71
    • 0022414227 scopus 로고
    • Cytolytic effect of polylysine on rabbit polymorphonuclear leukocytes
    • Elferink J.G. Cytolytic effect of polylysine on rabbit polymorphonuclear leukocytes. Inflammation. 9:1985;321-331.
    • (1985) Inflammation , vol.9 , pp. 321-331
    • Elferink, J.G.1
  • 73
    • 0027218376 scopus 로고
    • Defensins promote fusion and lysis of negatively charged membranes
    • Fujii G., Selsted M.E., Eisenberg D. Defensins promote fusion and lysis of negatively charged membranes. Protein Sci. 2:1993;1301-1312.
    • (1993) Protein Sci. , vol.2 , pp. 1301-1312
    • Fujii, G.1    Selsted, M.E.2    Eisenberg, D.3
  • 74
    • 0026655684 scopus 로고
    • Influenza virus hemagglutinin HA-2 N-terminal fusogenic peptides augment gene transfer by transferrin-polylysine-DNA complexes: Toward a synthetic virus-like gene-transfer vehicle
    • Wagner E., Plank C., Zatloukal K., Cotten M., Birnstiel M.L. Influenza virus hemagglutinin HA-2 N-terminal fusogenic peptides augment gene transfer by transferrin-polylysine-DNA complexes: toward a synthetic virus-like gene-transfer vehicle. Proc. Natl. Acad. Sci. U.S.A. 89:1992;7934-7938.
    • (1992) Proc. Natl. Acad. Sci. U.S.A. , vol.89 , pp. 7934-7938
    • Wagner, E.1    Plank, C.2    Zatloukal, K.3    Cotten, M.4    Birnstiel, M.L.5
  • 76
    • 0028558990 scopus 로고
    • Overexpression of human methylmalonyl CoA mutase in mice after in vivo gene transfer with asialoglycoprotein/polylysine/DNA complexes
    • Stankovics J., Crane A.M., Andrews E., Wu C.H., Wu G.Y., Ledley F.D. Overexpression of human methylmalonyl CoA mutase in mice after in vivo gene transfer with asialoglycoprotein/polylysine/DNA complexes. Hum. Gene Ther. 5:1994;1095-1104.
    • (1994) Hum. Gene Ther. , vol.5 , pp. 1095-1104
    • Stankovics, J.1    Crane, A.M.2    Andrews, E.3    Wu, C.H.4    Wu, G.Y.5    Ledley, F.D.6
  • 77
    • 0029761375 scopus 로고    scopus 로고
    • Immunologic responses to gene transfer into mice via the polymeric immunoglobulin receptor
    • Ferkol T., Pellicena-Palle A., Eckman E.et al. Immunologic responses to gene transfer into mice via the polymeric immunoglobulin receptor. Gene Ther. 3:1996;669-678.
    • (1996) Gene Ther. , vol.3 , pp. 669-678
    • Ferkol, T.1    Pellicena-Palle, A.2    Eckman, E.3
  • 78
    • 0027988268 scopus 로고
    • Immunogenicity of poly-D-lysine, a potential polymeric drug carrier
    • Vermeersch H., Remon J.P. Immunogenicity of poly-D-lysine, a potential polymeric drug carrier. J. Control. Release. 32:1994;225-229.
    • (1994) J. Control. Release , vol.32 , pp. 225-229
    • Vermeersch, H.1    Remon, J.P.2
  • 79
    • 0029789793 scopus 로고    scopus 로고
    • Activation of the complement system by synthetic DNA complexes: A potential barrier for intravenous gene delivery
    • Plank C., Mechtler K., Szoka C.P., Wagner E. Activation of the complement system by synthetic DNA complexes: a potential barrier for intravenous gene delivery. Hum. Gene Ther. 7:1996;1437-1446.
    • (1996) Hum. Gene Ther. , vol.7 , pp. 1437-1446
    • Plank, C.1    Mechtler, K.2    Szoka, C.P.3    Wagner, E.4
  • 80
    • 0027933122 scopus 로고
    • Carbohydrate receptor-mediated gene transfer to human T leukaemic cells
    • Thurnher M., Wagner E., Clausen H.et al. Carbohydrate receptor-mediated gene transfer to human T leukaemic cells. Glycobiology. 4:1994;429-435.
    • (1994) Glycobiology , vol.4 , pp. 429-435
    • Thurnher, M.1    Wagner, E.2    Clausen, H.3
  • 81
    • 0028982477 scopus 로고
    • Receptor-mediated gene transfer into human T lymphocytes via binding of DNA/CD3 antibody particles to the CD3 T cell receptor complex
    • Buschle M., Cotten M., Kirlappos H.et al. Receptor-mediated gene transfer into human T lymphocytes via binding of DNA/CD3 antibody particles to the CD3 T cell receptor complex. Hum. Gene Ther. 6:1995;753-761.
    • (1995) Hum. Gene Ther. , vol.6 , pp. 753-761
    • Buschle, M.1    Cotten, M.2    Kirlappos, H.3
  • 82
    • 0028891920 scopus 로고
    • CD5-mediated specific delivery of DNA to T lymphocytes: Compartmentalization augmented by adenovirus
    • Merwin J.R., Carmichael E.P., Noell G.S.et al. CD5-mediated specific delivery of DNA to T lymphocytes: compartmentalization augmented by adenovirus. J. Immunol. Methods. 186:1995;257-266.
    • (1995) J. Immunol. Methods , vol.186 , pp. 257-266
    • Merwin, J.R.1    Carmichael, E.P.2    Noell, G.S.3
  • 83
    • 0030069992 scopus 로고    scopus 로고
    • Targeted gene transfer to human hematopoietic progenitor cell lines through the c-kit receptor
    • Schwarzenberger P., Spence S.E., Gooya J.M.et al. Targeted gene transfer to human hematopoietic progenitor cell lines through the c-kit receptor. Blood. 87:1996;472-478.
    • (1996) Blood , vol.87 , pp. 472-478
    • Schwarzenberger, P.1    Spence, S.E.2    Gooya, J.M.3
  • 84
    • 0029979929 scopus 로고    scopus 로고
    • Putative role of chloroquine in gene transfer into a human hepatoma cell line by DNA/lactosylated polylysine complexes
    • Erbacher P., Roche A.C., Monsigny M., Midoux P. Putative role of chloroquine in gene transfer into a human hepatoma cell line by DNA/lactosylated polylysine complexes. Exp. Cell Res. 225:1996;186-194.
    • (1996) Exp. Cell Res. , vol.225 , pp. 186-194
    • Erbacher, P.1    Roche, A.C.2    Monsigny, M.3    Midoux, P.4
  • 85
    • 0023212742 scopus 로고
    • Receptor-mediated in vitro gene transformation by a soluble DNA carrier system
    • Wu G.Y., Wu C.H. Receptor-mediated in vitro gene transformation by a soluble DNA carrier system. J. Biol. Chem. 262:1987;4429-4432.
    • (1987) J. Biol. Chem. , vol.262 , pp. 4429-4432
    • Wu, G.Y.1    Wu, C.H.2
  • 86
    • 0029294596 scopus 로고
    • Targeted gene delivery with a low molecular weight glycopeptide carrier
    • Wadhwa M.S., Knoell D.L., Young A.P., Rice K.G. Targeted gene delivery with a low molecular weight glycopeptide carrier. Bioconjugate Chem. 6:1995;283-291.
    • (1995) Bioconjugate Chem. , vol.6 , pp. 283-291
    • Wadhwa, M.S.1    Knoell, D.L.2    Young, A.P.3    Rice, K.G.4
  • 87
    • 0026952599 scopus 로고
    • Gene transfer into hepatocytes using asialoglycoprotein receptor mediated endocytosis of DNA complexed with an artificial tetra-antennary galactose ligand
    • Plank C., Zatloukal K., Cotten M., Mechtler K., Wagner E. Gene transfer into hepatocytes using asialoglycoprotein receptor mediated endocytosis of DNA complexed with an artificial tetra-antennary galactose ligand. Bioconjugate Chem. 3:1992;533-539.
    • (1992) Bioconjugate Chem. , vol.3 , pp. 533-539
    • Plank, C.1    Zatloukal, K.2    Cotten, M.3    Mechtler, K.4    Wagner, E.5
  • 88
    • 0028329931 scopus 로고
    • Biochemical and functional analysis of an adenovirus-based ligand complex for gene transfer
    • Fisher K.J., Wilson J.M. Biochemical and functional analysis of an adenovirus-based ligand complex for gene transfer. Biochem. J. 299:1994;49-58.
    • (1994) Biochem. J. , vol.299 , pp. 49-58
    • Fisher, K.J.1    Wilson, J.M.2
  • 89
    • 0028954476 scopus 로고
    • Malarial circumsporozoite protein is a novel gene delivery vehicle to primary hepatocyte cultures and cultured cells
    • Ding Z.-M., Cristiano R.J., Roth J.A., Takacs B., Kuo M.T. Malarial circumsporozoite protein is a novel gene delivery vehicle to primary hepatocyte cultures and cultured cells. J. Biol. Chem. 270:1995;3667-3676.
    • (1995) J. Biol. Chem. , vol.270 , pp. 3667-3676
    • Ding, Z.-M.1    Cristiano, R.J.2    Roth, J.A.3    Takacs, B.4    Kuo, M.T.5
  • 90
    • 0028309752 scopus 로고
    • Incorporation of adenovirus into a ligand-based DNA carrier system results in retention of original receptor specificity and enhances targeted gene expression
    • Wu G.Y., Zhan P., Sze L.L., Rosenberg A.R., Wu C.H. Incorporation of adenovirus into a ligand-based DNA carrier system results in retention of original receptor specificity and enhances targeted gene expression. J. Biol. Chem. 269:1994;11542-11546.
    • (1994) J. Biol. Chem. , vol.269 , pp. 11542-11546
    • Wu, G.Y.1    Zhan, P.2    Sze, L.L.3    Rosenberg, A.R.4    Wu, C.H.5
  • 91
    • 0028534622 scopus 로고
    • 3, a synthetic glycopeptide ligand for the asialoglycoprotein receptor
    • 3, a synthetic glycopeptide ligand for the asialoglycoprotein receptor. Bioconjugate Chem. 5:1994;612-620.
    • (1994) Bioconjugate Chem. , vol.5 , pp. 612-620
    • Merwin, J.R.1    Noell, G.S.2    Thomas, W.L.3
  • 92
    • 0026719220 scopus 로고
    • Receptor-mediated endocytosis and nuclear transport of a transfecting DNA construct
    • Rosenkranz A.A., Yachmenev S.V., Jans D.A.et al. Receptor-mediated endocytosis and nuclear transport of a transfecting DNA construct. Exp. Cell Res. 199:1992;323-329.
    • (1992) Exp. Cell Res. , vol.199 , pp. 323-329
    • Rosenkranz, A.A.1    Yachmenev, S.V.2    Jans, D.A.3
  • 93
    • 0027447460 scopus 로고
    • Hepatic gene therapy: Adenovirus enhancement of receptor-mediated gene delivery
    • Cristiano R., Smith L., Woo S. Hepatic gene therapy: adenovirus enhancement of receptor-mediated gene delivery. Proc. Natl. Acad. Sci. U.S.A. 90:1993;2122-2126.
    • (1993) Proc. Natl. Acad. Sci. U.S.A. , vol.90 , pp. 2122-2126
    • Cristiano, R.1    Smith, L.2    Woo, S.3
  • 94
    • 0027133660 scopus 로고
    • Hepatic gene therapy: Efficient gene delivery and expression in primary hepatocytes utilizing a conjugated adenovirus-DNA complex
    • Cristiano R., Smith L., Woo S. Hepatic gene therapy: efficient gene delivery and expression in primary hepatocytes utilizing a conjugated adenovirus-DNA complex. Proc. Natl. Acad. Sci. U.S.A. 90:1993;11548-11552.
    • (1993) Proc. Natl. Acad. Sci. U.S.A. , vol.90 , pp. 11548-11552
    • Cristiano, R.1    Smith, L.2    Woo, S.3
  • 95
    • 0029360588 scopus 로고
    • Transfection of folate-polylysine DNA complexes: Evidence for lysosomal delivery
    • Mislick K.A., Baldeschwieler J.D., Kayyem J.F., Meade T.J. Transfection of folate-polylysine DNA complexes: evidence for lysosomal delivery. Bioconjugate Chem. 6:1995;512-515.
    • (1995) Bioconjugate Chem. , vol.6 , pp. 512-515
    • Mislick, K.A.1    Baldeschwieler, J.D.2    Kayyem, J.F.3    Meade, T.J.4
  • 96
    • 0028430957 scopus 로고
    • Folate receptor mediated DNA delivery into tumor cells: Potosomal disruption results in enhanced gene expression
    • Gottschalk S., Cristiano R.J., Smith L.C., Woo S.L.C. Folate receptor mediated DNA delivery into tumor cells: potosomal disruption results in enhanced gene expression. Gene Ther. 1:1994;185-191.
    • (1994) Gene Ther. , vol.1 , pp. 185-191
    • Gottschalk, S.1    Cristiano, R.J.2    Smith, L.C.3    Woo, S.L.C.4
  • 98
    • 0028067878 scopus 로고
    • Lectin conjugate-directed gene transfer to airway epithelial cells
    • Yin W., Cheng P.-W. Lectin conjugate-directed gene transfer to airway epithelial cells. Biochem. Biophys. Res. Commun. 205:1994;826-833.
    • (1994) Biochem. Biophys. Res. Commun. , vol.205 , pp. 826-833
    • Yin, W.1    Cheng, P.-W.2
  • 99
    • 0028052170 scopus 로고
    • Targeted gene delivery to alveolar macrophages via Fc receptor-mediated endocytosis
    • Rojanasakul Y., Wang L.Y., Malanga C.J., Ma J.K.H., Liaw J. Targeted gene delivery to alveolar macrophages via Fc receptor-mediated endocytosis. Pharm. Res. 11:1994;1731-1736.
    • (1994) Pharm. Res. , vol.11 , pp. 1731-1736
    • Rojanasakul, Y.1    Wang, L.Y.2    Malanga, C.J.3    Ma, J.K.H.4    Liaw, J.5
  • 100
    • 0026668198 scopus 로고
    • Cationic liposomes enhance targeted delivery and expression of exogenous DNA mediated by N-terminal modified poly-L-lysine-antibody conjugate in mouse lung endothelial cells
    • Trubetskoy V.S., Torchilin V.P., Kennel S., Huang L. Cationic liposomes enhance targeted delivery and expression of exogenous DNA mediated by N-terminal modified poly-L-lysine-antibody conjugate in mouse lung endothelial cells. Biochim. Biophys. Acta. 1131:1992;311-313.
    • (1992) Biochim. Biophys. Acta , vol.1131 , pp. 311-313
    • Trubetskoy, V.S.1    Torchilin, V.P.2    Kennel, S.3    Huang, L.4
  • 101
    • 0028989345 scopus 로고
    • Surfactant protein A-polylysine conjugates for delivery of DNA to airway cells in culture
    • Ross G.F., Morris R.E., Ciraolo G.et al. Surfactant protein A-polylysine conjugates for delivery of DNA to airway cells in culture. Hum. Gene Ther. 6:1995;31-40.
    • (1995) Hum. Gene Ther. , vol.6 , pp. 31-40
    • Ross, G.F.1    Morris, R.E.2    Ciraolo, G.3
  • 102
    • 0028301813 scopus 로고
    • Utilization of modified surfactant-associated protein B for delivery of DNA to airway cells in culture
    • Baatz J.E., Bruno M.D., Ciraolo P.J.et al. Utilization of modified surfactant-associated protein B for delivery of DNA to airway cells in culture. Proc. Natl. Acad. Sci. U.S.A. 91:1994;2547-2551.
    • (1994) Proc. Natl. Acad. Sci. U.S.A. , vol.91 , pp. 2547-2551
    • Baatz, J.E.1    Bruno, M.D.2    Ciraolo, P.J.3
  • 103
    • 0027954666 scopus 로고
    • A novel gene delivery system using EGF receptor-mediated endocytosis
    • Chen J., Gamou S., Takayanagi A., Shimizu N. A novel gene delivery system using EGF receptor-mediated endocytosis. FEBS Lett. 338:1994;167-169.
    • (1994) FEBS Lett. , vol.338 , pp. 167-169
    • Chen, J.1    Gamou, S.2    Takayanagi, A.3    Shimizu, N.4
  • 104
    • 0029079747 scopus 로고
    • Efficient gene delivery and expression in mammalian cells using DNA coupled with perfringolysin O
    • Gottschalk S., Tweten R.K., Smith L.C., Woo S.L.C. Efficient gene delivery and expression in mammalian cells using DNA coupled with perfringolysin O. Gene Ther. 2:1995;498-503.
    • (1995) Gene Ther. , vol.2 , pp. 498-503
    • Gottschalk, S.1    Tweten, R.K.2    Smith, L.C.3    Woo, S.L.C.4
  • 105
    • 0027365343 scopus 로고
    • Gene transfer into respiratory epithelial cells by targeting the polymeric immunoglobulin receptor
    • Ferkol T., Kaetzel C.S., Davis P.B. Gene transfer into respiratory epithelial cells by targeting the polymeric immunoglobulin receptor. J. Clin. Invest. 92:1993;2394-2400.
    • (1993) J. Clin. Invest. , vol.92 , pp. 2394-2400
    • Ferkol, T.1    Kaetzel, C.S.2    Davis, P.B.3
  • 107
    • 0026687453 scopus 로고
    • Coupling of adenovirus to transferrin-polylysine/DNA complexes greatly enhances receptor-mediated gene delivery and expression of transfected genes
    • Wagner E., Zatloukal K., Cotten M.et al. Coupling of adenovirus to transferrin-polylysine/DNA complexes greatly enhances receptor-mediated gene delivery and expression of transfected genes. Proc. Natl. Acad. Sci. U.S.A. 89:1992;6099-6103.
    • (1992) Proc. Natl. Acad. Sci. U.S.A. , vol.89 , pp. 6099-6103
    • Wagner, E.1    Zatloukal, K.2    Cotten, M.3
  • 108
    • 0027076361 scopus 로고
    • Transferrinfection: A highly efficient way to express gene constructs in eukaryotic cells
    • Zatloukal K., Wagner E., Cotten M.et al. Transferrinfection: a highly efficient way to express gene constructs in eukaryotic cells. Ann. N.Y. Acad. Sci. 660:1992;136-153.
    • (1992) Ann. N.Y. Acad. Sci. , vol.660 , pp. 136-153
    • Zatloukal, K.1    Wagner, E.2    Cotten, M.3
  • 109
    • 0026755818 scopus 로고
    • High efficiency receptor-mediated delivery of small and large (48 kb) gene constructs using the endosome disruption activity of defective or chemically inactivated adenovirus particles
    • Cotten M., Wagner E., Zatloukal K., Phillips S., Curiel D.T., Birnstiel M.L. High efficiency receptor-mediated delivery of small and large (48 kb) gene constructs using the endosome disruption activity of defective or chemically inactivated adenovirus particles. Proc. Natl. Acad. Sci. U.S.A. 89:1992;6094-6098.
    • (1992) Proc. Natl. Acad. Sci. U.S.A. , vol.89 , pp. 6094-6098
    • Cotten, M.1    Wagner, E.2    Zatloukal, K.3    Phillips, S.4    Curiel, D.T.5    Birnstiel, M.L.6
  • 110
    • 0026847713 scopus 로고
    • High-efficiency gene transfer mediated by adenovirus coupled to DNA-polylysine complexes
    • Curiel D.T., Wagner E., Cotten M.et al. High-efficiency gene transfer mediated by adenovirus coupled to DNA-polylysine complexes. Hum. Gene Ther. 3:1992;147-154.
    • (1992) Hum. Gene Ther. , vol.3 , pp. 147-154
    • Curiel, D.T.1    Wagner, E.2    Cotten, M.3
  • 111
    • 0027215910 scopus 로고
    • Chicken adenovirus (CELO virus) particles augment receptor-mediated DNA delivery to mammalian cells and yield exceptional levels of stable transformants
    • Cotten M., Wagner E., Zatloukal K., Birnstiel M.L. Chicken adenovirus (CELO virus) particles augment receptor-mediated DNA delivery to mammalian cells and yield exceptional levels of stable transformants. J. Virol. 67:1993;3777-3785.
    • (1993) J. Virol. , vol.67 , pp. 3777-3785
    • Cotten, M.1    Wagner, E.2    Zatloukal, K.3    Birnstiel, M.L.4
  • 112
    • 0028852342 scopus 로고
    • Rhinovirus-mediated endosomal release of transfection complexes
    • Zauner W., Blaas D., Kuechler E., Wagner E. Rhinovirus-mediated endosomal release of transfection complexes. J. Virol. 69:1995;1085-1092.
    • (1995) J. Virol. , vol.69 , pp. 1085-1092
    • Zauner, W.1    Blaas, D.2    Kuechler, E.3    Wagner, E.4
  • 114
    • 0026184419 scopus 로고
    • DNA-binding transferrin conjugates as functional gene delivery agents: Synthesis by linkage of polylysine or ethidium homodimer to the transferrin carbohydrate moiety
    • Wagner E., Cotten M., Mechtler K., Kirlappos H., Birnstiel M.L. DNA-binding transferrin conjugates as functional gene delivery agents: synthesis by linkage of polylysine or ethidium homodimer to the transferrin carbohydrate moiety. Bioconjugate Chem. 2:1991;226-231.
    • (1991) Bioconjugate Chem. , vol.2 , pp. 226-231
    • Wagner, E.1    Cotten, M.2    Mechtler, K.3    Kirlappos, H.4    Birnstiel, M.L.5
  • 116
    • 0028508634 scopus 로고
    • Molecular conjugate vectors mediate efficient gene transfer into gastrointestinal epithelial cells
    • Batra R.K., Berschneider H., Curiel D.T. Molecular conjugate vectors mediate efficient gene transfer into gastrointestinal epithelial cells. Cancer Gene Ther. 1:1994;185-192.
    • (1994) Cancer Gene Ther. , vol.1 , pp. 185-192
    • Batra, R.K.1    Berschneider, H.2    Curiel, D.T.3
  • 117
    • 0028076792 scopus 로고
    • Efficient transfection of primary cells in a canine hemophilia B model using adenovirus-polylysine-DNA complexes
    • Lozier J.N., Thompson A.R., Hu P.-C.et al. Efficient transfection of primary cells in a canine hemophilia B model using adenovirus-polylysine-DNA complexes. Hum. Gene Ther. 5:1994;313-322.
    • (1994) Hum. Gene Ther. , vol.5 , pp. 313-322
    • Lozier, J.N.1    Thompson, A.R.2    Hu, P.-C.3
  • 118
    • 0027240218 scopus 로고
    • Receptor-targeted transfection using stable maleimido-transferrin/thio-poly-L-lysine conjugates
    • Taxman D.J., Lee E.S., Wojchowski D.M. Receptor-targeted transfection using stable maleimido-transferrin/thio-poly-L-lysine conjugates. Anal. Biochem. 213:1993;97-103.
    • (1993) Anal. Biochem. , vol.213 , pp. 97-103
    • Taxman, D.J.1    Lee, E.S.2    Wojchowski, D.M.3
  • 119
    • 0028670905 scopus 로고
    • High-efficiency gene transfer to autologous rabbit jugular vein grafts using adenovirus-transferrin/polylysine-DNA complexes
    • Kupfer J.M., Ruan X.M., Liu G., Matloff J., Forrester J., Chaux A. High-efficiency gene transfer to autologous rabbit jugular vein grafts using adenovirus-transferrin/polylysine-DNA complexes. Hum. Gene Ther. 5:1994;1437-1443.
    • (1994) Hum. Gene Ther. , vol.5 , pp. 1437-1443
    • Kupfer, J.M.1    Ruan, X.M.2    Liu, G.3    Matloff, J.4    Forrester, J.5    Chaux, A.6
  • 120
    • 0027793751 scopus 로고
    • Studies on the transfer of DNA into cells through use of avidin-polylysine conjugates complexed to biotinylated transferrin and DNA
    • Strydom S., van Jaarsveld P., van Helden E., Ariatti M., Hawtrey A. Studies on the transfer of DNA into cells through use of avidin-polylysine conjugates complexed to biotinylated transferrin and DNA. J. Drug Target. 1:1993;165-174.
    • (1993) J. Drug Target. , vol.1 , pp. 165-174
    • Strydom, S.1    Van Jaarsveld, P.2    Van Helden, E.3    Ariatti, M.4    Hawtrey, A.5
  • 121
    • 0026597952 scopus 로고
    • Interaction of polycations with cell-surface negative charges of epithelial cells
    • Singh A.K., Kasinath B.S., Lewis E.J. Interaction of polycations with cell-surface negative charges of epithelial cells. Biochim. Biophys. Acta. 1120:1992;337-342.
    • (1992) Biochim. Biophys. Acta , vol.1120 , pp. 337-342
    • Singh, A.K.1    Kasinath, B.S.2    Lewis, E.J.3
  • 122
    • 0023932257 scopus 로고
    • Methotrexate-poly(lysine) as a selective agent for mutants of Chinese Hamster Ovary cells defective in endocytosis
    • Ryser H.J.-P., Mandel R., Hacobian A., Shen W.-C. Methotrexate-poly(lysine) as a selective agent for mutants of Chinese Hamster Ovary cells defective in endocytosis. J. Cell. Physiol. 135:1988;277-284.
    • (1988) J. Cell. Physiol. , vol.135 , pp. 277-284
    • Ryser, H.J.-P.1    Mandel, R.2    Hacobian, A.3    Shen, W.-C.4
  • 123
    • 0011766331 scopus 로고
    • Conjugation of poly-L-lysine to albumin and horseradish peroxidase: A novel method of enhancing the cellular uptake of proteins
    • Shen W.-C., Ryser H.J.-P. Conjugation of poly-L-lysine to albumin and horseradish peroxidase: a novel method of enhancing the cellular uptake of proteins. Proc. Natl. Acad. Sci. U.S.A. 75:1978;1872-1876.
    • (1978) Proc. Natl. Acad. Sci. U.S.A. , vol.75 , pp. 1872-1876
    • Shen, W.-C.1    Ryser, H.J.-P.2
  • 124
    • 0019947607 scopus 로고
    • The cellular uptake of horseradish peroxidase and its poly(lysine) conjugate by cultured fibroblasts is qualitatively similar despite a 900-fold difference in rate
    • Ryser H.J.-P., Drummond I., Shen W.-C. The cellular uptake of horseradish peroxidase and its poly(lysine) conjugate by cultured fibroblasts is qualitatively similar despite a 900-fold difference in rate. J. Cell. Physiol. 113:1982;167-178.
    • (1982) J. Cell. Physiol. , vol.113 , pp. 167-178
    • Ryser, H.J.-P.1    Drummond, I.2    Shen, W.-C.3
  • 125
    • 0025398291 scopus 로고
    • Biological activity of oligonucleotide-poly-L-lysine conjugates: Mechanism of cell uptake
    • Leonetti J.-P., Degols G., Lebleu B. Biological activity of oligonucleotide-poly-L-lysine conjugates: mechanism of cell uptake. Bioconjugate Chem. 1:1990;149-153.
    • (1990) Bioconjugate Chem. , vol.1 , pp. 149-153
    • Leonetti, J.-P.1    Degols, G.2    Lebleu, B.3
  • 126
    • 0025735562 scopus 로고
    • Lipophilic polylysines mediate efficient DNA transfection in mammalian cells
    • Zhou X., Klibanov A.L., Huang L. Lipophilic polylysines mediate efficient DNA transfection in mammalian cells. Biochim. Biophys. Acta. 1065:1991;8-14.
    • (1991) Biochim. Biophys. Acta , vol.1065 , pp. 8-14
    • Zhou, X.1    Klibanov, A.L.2    Huang, L.3
  • 127
    • 0028097638 scopus 로고
    • DNA transfection mediated by cationic liposomes containing lipopolylysine: Characterization and mechanism of action
    • Zhou X., Huang L. DNA transfection mediated by cationic liposomes containing lipopolylysine: characterization and mechanism of action. Biochim. Biophys. Acta. 1189:1994;195-203.
    • (1994) Biochim. Biophys. Acta , vol.1189 , pp. 195-203
    • Zhou, X.1    Huang, L.2
  • 128
    • 0026668198 scopus 로고
    • Cationic liposomes enhance targeted delivery and expression of exogenous DNA mediated by N-terminal modified poly-L-lysine-antibody conjugate in mouse lung endothelial cells
    • Trubetskoy V.S., Torchilin V.P., Kennel S., Huang L. Cationic liposomes enhance targeted delivery and expression of exogenous DNA mediated by N-terminal modified poly-L-lysine-antibody conjugate in mouse lung endothelial cells. Biochim. Biophys. Acta. 1131:1992;311-313.
    • (1992) Biochim. Biophys. Acta , vol.1131 , pp. 311-313
    • Trubetskoy, V.S.1    Torchilin, V.P.2    Kennel, S.3    Huang, L.4
  • 129
    • 0029932762 scopus 로고    scopus 로고
    • Folate-targeted, anionic liposome-entrapped polylysine-condensed DNA for tumor cell-specific gene transfer
    • Lee R.J., Huang L. Folate-targeted, anionic liposome-entrapped polylysine-condensed DNA for tumor cell-specific gene transfer. J. Biol. Chem. 271:1996;8481-8487.
    • (1996) J. Biol. Chem. , vol.271 , pp. 8481-8487
    • Lee, R.J.1    Huang, L.2
  • 130
    • 0030038942 scopus 로고    scopus 로고
    • Potentiation of cationic liposome-mediated gene delivery by polycations
    • Gao X., Huang L. Potentiation of cationic liposome-mediated gene delivery by polycations. Biochemistry. 35:1996;1027-1036.
    • (1996) Biochemistry , vol.35 , pp. 1027-1036
    • Gao, X.1    Huang, L.2
  • 131
    • 0029982279 scopus 로고    scopus 로고
    • Condensation of plasmid DNA with polylysine improves liposome-mediated gene transfer into established and primary muscle cells
    • Vitiello L., Chonn A., Wasserman J.D., Duff C., Worton R.G. Condensation of plasmid DNA with polylysine improves liposome-mediated gene transfer into established and primary muscle cells. Gene Ther. 3:1996;396-404.
    • (1996) Gene Ther. , vol.3 , pp. 396-404
    • Vitiello, L.1    Chonn, A.2    Wasserman, J.D.3    Duff, C.4    Worton, R.G.5
  • 133
    • 0020973226 scopus 로고
    • Inhibitors of lysosomal function
    • Seglen P.O. Inhibitors of lysosomal function. Methods Enzymol. 96:1983;737-764.
    • (1983) Methods Enzymol. , vol.96 , pp. 737-764
    • Seglen, P.O.1
  • 134
    • 0028117742 scopus 로고
    • Psoralen treatment of adenovirus particles eliminates virus replication and transcription while maintaining the endosomolytic activity of the virus capsid
    • Cotten M., Saltik M., Kursa M., Wagner E., Maass G., Birnstiel M.L. Psoralen treatment of adenovirus particles eliminates virus replication and transcription while maintaining the endosomolytic activity of the virus capsid. Virology. 205:1994;251-261.
    • (1994) Virology , vol.205 , pp. 251-261
    • Cotten, M.1    Saltik, M.2    Kursa, M.3    Wagner, E.4    Maass, G.5    Birnstiel, M.L.6
  • 135
    • 0029120220 scopus 로고
    • Increased titer of recombinant AAV vectors by gene transfer with adenovirus coupled to DNA-polylysine complexes
    • Mamounas M., Leavitt M., Yu M., Wong Staal F. Increased titer of recombinant AAV vectors by gene transfer with adenovirus coupled to DNA-polylysine complexes. Gene Ther. 2:1995;429-432.
    • (1995) Gene Ther. , vol.2 , pp. 429-432
    • Mamounas, M.1    Leavitt, M.2    Yu, M.3    Wong Staal, F.4
  • 136
    • 0028860281 scopus 로고
    • Generation of high-titer retroviral vectors following receptor-mediated, adenovirus-augmented transfection
    • von Rüden T., Stingl L., Cotten M., Wagner E., Zatloukal K. Generation of high-titer retroviral vectors following receptor-mediated, adenovirus-augmented transfection. Biotechniques. 18:1995;484-489.
    • (1995) Biotechniques , vol.18 , pp. 484-489
    • Von Rüden, T.1    Stingl, L.2    Cotten, M.3    Wagner, E.4    Zatloukal, K.5
  • 137
    • 0029872770 scopus 로고    scopus 로고
    • Phase I study to the immunotherapy of metastatic malignant melanoma by a cancer vaccine consisting of autologous cancer cells transfected with the human IL-2 gene
    • Stingl G., Broecker E.-B., Mertelsmann R.et al. Phase I study to the immunotherapy of metastatic malignant melanoma by a cancer vaccine consisting of autologous cancer cells transfected with the human IL-2 gene. Hum. Gene Ther. 7:1996;551-563.
    • (1996) Hum. Gene Ther. , vol.7 , pp. 551-563
    • Stingl, G.1    Broecker, E.-B.2    Mertelsmann, R.3
  • 138
    • 0027511871 scopus 로고
    • Binding-incompetent adenovirus facilitates conjugate-mediated gene transfer by the receptor-mediated endocytosis pathway
    • Michael S.I., Huang C.-H., Rømer M.U., Wagner E., Hu P.-C., Curiel D.T. Binding-incompetent adenovirus facilitates conjugate-mediated gene transfer by the receptor-mediated endocytosis pathway. J. Biol. Chem. 268:1993;6866-6869.
    • (1993) J. Biol. Chem. , vol.268 , pp. 6866-6869
    • Michael, S.I.1    Huang, C.-H.2    Rømer, M.U.3    Wagner, E.4    Hu, P.-C.5    Curiel, D.T.6
  • 141
    • 0025719093 scopus 로고
    • Membrane fusion activity of the influenza virus hemagglutinin: Interaction of HA-2 N-terminal peptides with phospholipid vesicles
    • Rafalski M., Ortiz A., Rockwell A.et al. Membrane fusion activity of the influenza virus hemagglutinin: interaction of HA-2 N-terminal peptides with phospholipid vesicles. Biochemistry. 30:1991;10211-10220.
    • (1991) Biochemistry , vol.30 , pp. 10211-10220
    • Rafalski, M.1    Ortiz, A.2    Rockwell, A.3
  • 142
    • 0028199067 scopus 로고
    • The influence of endosome-disruptive peptides on gene transfer using synthetic virus-like gene transfer systems
    • Plank C., Oberhauser B., Mechtler K., Koch C., Wagner E. The influence of endosome-disruptive peptides on gene transfer using synthetic virus-like gene transfer systems. J. Biol. Chem. 269:1994;12918-12924.
    • (1994) J. Biol. Chem. , vol.269 , pp. 12918-12924
    • Plank, C.1    Oberhauser, B.2    Mechtler, K.3    Koch, C.4    Wagner, E.5
  • 143
    • 85053291087 scopus 로고
    • Enhancing endosomal exit of nucleic acids using pH-sensitive viral fusion peptides
    • S. Akhtar (Ed.), CRC Press, FL
    • B. Oberhauser, C. Plank, E. Wagner, Enhancing endosomal exit of nucleic acids using pH-sensitive viral fusion peptides, in: Delivery Strategies for Antisense Oligonucleotide Therapeutics, S. Akhtar (Ed.), CRC Press, FL, 1995, pp. 247-268.
    • (1995) Delivery Strategies for Antisense Oligonucleotide Therapeutics , pp. 247-268
    • Oberhauser, B.1    Plank, C.2    Wagner, E.3
  • 144
    • 0029941321 scopus 로고    scopus 로고
    • A novel DNA-peptide complex for efficient gene transfer and expression in mammalian cells
    • Gottschalk S., Sparrow J.T., Hauer J.et al. A novel DNA-peptide complex for efficient gene transfer and expression in mammalian cells. Gene Ther. 3:1996;448-457.
    • (1996) Gene Ther. , vol.3 , pp. 448-457
    • Gottschalk, S.1    Sparrow, J.T.2    Hauer, J.3
  • 145
    • 0019191911 scopus 로고
    • High efficiency transformation by direct microinjection of DNA into cultured mammalian cells
    • Capecchi M.R. High efficiency transformation by direct microinjection of DNA into cultured mammalian cells. Cell. 22:1980;479-488.
    • (1980) Cell , vol.22 , pp. 479-488
    • Capecchi, M.R.1
  • 146
    • 0027478062 scopus 로고
    • Efficient expression of miniprep plasmid DNA after needle micro-injection into somatic cells
    • Thorburn A.M., Alberts A.S. Efficient expression of miniprep plasmid DNA after needle micro-injection into somatic cells. Biotechniques. 14:1993;357-358.
    • (1993) Biotechniques , vol.14 , pp. 357-358
    • Thorburn, A.M.1    Alberts, A.S.2
  • 147
    • 0001305936 scopus 로고
    • Factors affecting the efficiency of introducing foreign DNA into mice by microinjecting eggs
    • Brinster R., Chen H., Trumbauer M., Yagle M., Palmiter R. Factors affecting the efficiency of introducing foreign DNA into mice by microinjecting eggs. Proc. Natl. Acad. Sci. U.S.A. 82:1985;4438-4442.
    • (1985) Proc. Natl. Acad. Sci. U.S.A. , vol.82 , pp. 4438-4442
    • Brinster, R.1    Chen, H.2    Trumbauer, M.3    Yagle, M.4    Palmiter, R.5
  • 149
    • 0029836074 scopus 로고    scopus 로고
    • Gene transfer into mammalian cells using histone-condensed plasmid DNA
    • Fritz J.D., Herweijer H., Zhang G., Wolff J.A. Gene transfer into mammalian cells using histone-condensed plasmid DNA. Hum. Gene Ther. 7:1996;1395-1404.
    • (1996) Hum. Gene Ther. , vol.7 , pp. 1395-1404
    • Fritz, J.D.1    Herweijer, H.2    Zhang, G.3    Wolff, J.A.4
  • 151
    • 0030099527 scopus 로고    scopus 로고
    • Transporting therapeutics across the blood-brain barrier
    • N.J. Abbott, I.A. Romero, I.A., Transporting therapeutics across the blood-brain barrier. Mol. Med. Today (1996) 106-113.
    • (1996) Mol. Med. Today , pp. 106-113
    • Abbott, N.J.1    Romero, I.A.2
  • 152
    • 0023811723 scopus 로고
    • Receptor-mediated gene delivery and expression in vivo
    • Wu G.Y., Wu C.H. Receptor-mediated gene delivery and expression in vivo. J. Biol. Chem. 263:1988;14621-14624.
    • (1988) J. Biol. Chem. , vol.263 , pp. 14621-14624
    • Wu, G.Y.1    Wu, C.H.2
  • 153
    • 0027233696 scopus 로고
    • Fate of DNA targeted to the liver by asialoglycoprotein receptor-mediated endocytosis in vivo
    • Chowdhury N.R., Wu C.H., Wu G.Y., Yerneni P.C., Bommineni V.R., Chowdhury J.R. Fate of DNA targeted to the liver by asialoglycoprotein receptor-mediated endocytosis in vivo. J. Biol. Chem. 268:1993;11265-11271.
    • (1993) J. Biol. Chem. , vol.268 , pp. 11265-11271
    • Chowdhury, N.R.1    Wu, C.H.2    Wu, G.Y.3    Yerneni, P.C.4    Bommineni, V.R.5    Chowdhury, J.R.6
  • 154
    • 0030050983 scopus 로고    scopus 로고
    • Microtubular disruption prolongs the expression of human bilirubin-uridinediphosphoglucuronate-glucuronsyltransferase-1 gene transferred into Gunn rat livers
    • Chowdhury N.R., Hays R.M., Bommineni V.R.et al. Microtubular disruption prolongs the expression of human bilirubin-uridinediphosphoglucuronate-glucuronsyltransferase-1 gene transferred into Gunn rat livers. J. Biol. Chem. 271:1996;2341-2346.
    • (1996) J. Biol. Chem. , vol.271 , pp. 2341-2346
    • Chowdhury, N.R.1    Hays, R.M.2    Bommineni, V.R.3
  • 155
    • 0024343077 scopus 로고
    • Targeting genes: Delivery and persistent expression of a foreign gene driven by mammalian regulatory elements in vivo
    • Wu G.Y., Wilson J.M., Wu C.H. Targeting genes: delivery and persistent expression of a foreign gene driven by mammalian regulatory elements in vivo. J. Biol. Chem. 264:1989;16985-16987.
    • (1989) J. Biol. Chem. , vol.264 , pp. 16985-16987
    • Wu, G.Y.1    Wilson, J.M.2    Wu, C.H.3
  • 156
    • 0026315433 scopus 로고
    • Receptor-mediated gene delivery in vivo. Partial correction of genetic analbumenia in Nagase rats
    • Wu G.Y., Wilson J.M., Shalaby F., Grossman M., Shafritz D.A., Wu C.H. Receptor-mediated gene delivery in vivo. Partial correction of genetic analbumenia in Nagase rats. J. Biol. Chem. 266:1991;14338-14342.
    • (1991) J. Biol. Chem. , vol.266 , pp. 14338-14342
    • Wu, G.Y.1    Wilson, J.M.2    Shalaby, F.3    Grossman, M.4    Shafritz, D.A.5    Wu, C.H.6
  • 157
    • 0027269967 scopus 로고
    • Direct in vivo gene transfer to airway epithelium employing adenovirus-polylysine-DNA complexes
    • Gao L., Wagner E., Cotten M.et al. Direct in vivo gene transfer to airway epithelium employing adenovirus-polylysine-DNA complexes. Hum. Gene Ther. 4:1993;17-24.
    • (1993) Hum. Gene Ther. , vol.4 , pp. 17-24
    • Gao, L.1    Wagner, E.2    Cotten, M.3


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