메뉴 건너뛰기




Volumn 131, Issue 2, 2011, Pages 453-460

SiRNA knockdown of ribonucleotide reductase inhibits melanoma cell line proliferation alone or synergistically with temozolomide

Author keywords

[No Author keywords available]

Indexed keywords

RIBONUCLEOTIDE REDUCTASE; SMALL INTERFERING RNA; TEMOZOLOMIDE;

EID: 78651388588     PISSN: 0022202X     EISSN: 15231747     Source Type: Journal    
DOI: 10.1038/jid.2010.310     Document Type: Article
Times cited : (35)

References (24)
  • 1
    • 30344448580 scopus 로고    scopus 로고
    • Effect of chemotherapy-induced DNA repair on oncolytic herpes simplex viral replication
    • Aghi M, Rabkin S, Martuza RL (2006) Effect of chemotherapy-induced DNA repair on oncolytic herpes simplex viral replication. J Natl Cancer Inst 98:38-50
    • (2006) J Natl Cancer Inst , vol.98 , pp. 38-50
    • Aghi, M.1    Rabkin, S.2    Martuza, R.L.3
  • 2
    • 59449085721 scopus 로고    scopus 로고
    • Genomic and molecular profiling predicts response to temozolomide in melanoma
    • Augustine CK, Yoo JS, Potti A et al. (2009) Genomic and molecular profiling predicts response to temozolomide in melanoma. Clin Cancer Res 15:502-10
    • (2009) Clin Cancer Res , vol.15 , pp. 502-510
    • Augustine, C.K.1    Yoo, J.S.2    Potti, A.3
  • 3
    • 34247567981 scopus 로고    scopus 로고
    • RNA interference targeting the R2 subunit of ribonucleotide reductase inhibits growth of tumor cells in vitro and in vivo
    • Avolio TM, Lee Y, Feng N et al. (2007) RNA interference targeting the R2 subunit of ribonucleotide reductase inhibits growth of tumor cells in vitro and in vivo. Anti-Cancer Drugs 18:377-88
    • (2007) Anti-Cancer Drugs , vol.18 , pp. 377-388
    • Avolio, T.M.1    Lee, Y.2    Feng, N.3
  • 4
    • 33947696667 scopus 로고    scopus 로고
    • Physicochemical and biological characterization of targeted, nucleic acid-containing nanoparticles
    • Bartlett DW, Davis ME (2007) Physicochemical and biological characterization of targeted, nucleic acid-containing nanoparticles. Bioconjugate Chem 18:456-68
    • (2007) Bioconjugate Chem , vol.18 , pp. 456-468
    • Bartlett, D.W.1    Davis, M.E.2
  • 5
    • 66349104023 scopus 로고    scopus 로고
    • Antifolate activity of pyrimethamine enhances temozolomide-induced cytotoxicity in melanoma cells
    • Chen M, Osman I, Orlow SJ (2009) Antifolate activity of pyrimethamine enhances temozolomide-induced cytotoxicity in melanoma cells. Mol Cancer Res 7:703-12
    • (2009) Mol Cancer Res , vol.7 , pp. 703-712
    • Chen, M.1    Osman, I.2    Orlow, S.J.3
  • 6
    • 33748794547 scopus 로고    scopus 로고
    • Theoretical basis, experimental design, and computerized simulation of synergism and antagonism in drug combination studies
    • Chou TC (2006) Theoretical basis, experimental design, and computerized simulation of synergism and antagonism in drug combination studies. Pharmacol Rev 58:621-81
    • (2006) Pharmacol Rev , vol.58 , pp. 621-681
    • Chou, T.C.1
  • 7
    • 67249128859 scopus 로고    scopus 로고
    • The first targeted delivery of siRNA in humans via a self-assembling, cyclodextrin polymer-based nanoparticle: From concept to clinic
    • Davis ME (2009) The first targeted delivery of siRNA in humans via a self-assembling, cyclodextrin polymer-based nanoparticle: from concept to clinic. Mol Pharmaceutics 6:659-68
    • (2009) Mol Pharmaceutics , vol.6 , pp. 659-668
    • Davis, M.E.1
  • 8
    • 77951132901 scopus 로고    scopus 로고
    • Evidence of RNAi in humans from systemically administered siRNA via targeted nanoparticles
    • Davis ME, Zuckerman JE, Choi CH et al. (2010) Evidence of RNAi in humans from systemically administered siRNA via targeted nanoparticles. Nature 464:1067-70
    • (2010) Nature , vol.464 , pp. 1067-1070
    • Davis, M.E.1    Zuckerman, J.E.2    Choi, C.H.3
  • 9
    • 21344458583 scopus 로고    scopus 로고
    • A phase i study of antisense oligonucleotide GTI-2040 given by continuous intravenous infusion in patients with advanced solid tumors
    • Desai AA, Schilsky RL, Young A et al. (2005) A phase I study of antisense oligonucleotide GTI-2040 given by continuous intravenous infusion in patients with advanced solid tumors. Ann Oncol 16:958-65
    • (2005) Ann Oncol , vol.16 , pp. 958-965
    • Desai, A.A.1    Schilsky, R.L.2    Young, A.3
  • 10
    • 1542742114 scopus 로고    scopus 로고
    • RNA interference targeting the M2 subunit of ribonucleotide reductase enhances pancreatic adenocarcinoma chemosensitivity to gemcitabine
    • Duxbury MS, Ito H, Zinner MJ et al. (2004) RNA interference targeting the M2 subunit of ribonucleotide reductase enhances pancreatic adenocarcinoma chemosensitivity to gemcitabine. Oncogene 23:1539-48
    • (2004) Oncogene , vol.23 , pp. 1539-1548
    • Duxbury, M.S.1    Ito, H.2    Zinner, M.J.3
  • 11
    • 0022260274 scopus 로고
    • Cell cycle-dependent expression of mammalian ribonucleotide reductase. Differential regulation of the two subunits
    • Engstrom Y, Eriksson SJildevik I etal. (1985) Cell cycle-dependent expression of mammalian ribonucleotide reductase. Differential regulation of the two subunits. J Biol Chem 260:9114-6
    • (1985) J Biol Chem , vol.260 , pp. 9114-9116
    • Engstrom, Y.1    Eriksson, S.2    Jildevik, I.3
  • 12
    • 33847220364 scopus 로고    scopus 로고
    • Melanoma biology and new targeted therapy
    • Gray-Schopfer V, Wellbrock C, Marais R (2007) Melanoma biology and new targeted therapy. Nature 445:851-7
    • (2007) Nature , vol.445 , pp. 851-857
    • Gray-Schopfer, V.1    Wellbrock, C.2    Marais, R.3
  • 13
    • 34247493628 scopus 로고    scopus 로고
    • Potent siRNA inhibitors of ribonucleotide reductase subunit RRM2 reduce cell proliferation in vitro and in vivo
    • Heidel JD, Liu JY, Yen Y et al. (2007a) Potent siRNA inhibitors of ribonucleotide reductase subunit RRM2 reduce cell proliferation in vitro and in vivo. Clin Cancer Res 13:2207-15
    • (2007) Clin Cancer Res , vol.13 , pp. 2207-2215
    • Heidel, J.D.1    Liu, J.Y.2    Yen, Y.3
  • 14
    • 34347272315 scopus 로고    scopus 로고
    • Administration in non-human primates of escalating intravenous doses of targeted nanoparticles containing ribonucleotide reductase subunit M2 siRNA
    • Heidel JD, Yu Z, Liu JY etal. (2007b) Administration in non-human primates of escalating intravenous doses of targeted nanoparticles containing ribonucleotide reductase subunit M2 siRNA. Proc Natl Acad Sci USA 104:5715-21
    • (2007) Proc Natl Acad Sci USA , vol.104 , pp. 5715-5721
    • Heidel, J.D.1    Yu, Z.2    Liu, J.Y.3
  • 15
    • 77950954465 scopus 로고    scopus 로고
    • Differential sensitivity of melanoma cell lines with BRAF V600E mutation to the specific BRAF inhibitor PLX4032/RG7204
    • in press
    • Søndergaard JN, Nazarian R, Qi W et al. (2010) Differential sensitivity of melanoma cell lines with BRAF V600E mutation to the specific BRAF inhibitor PLX4032/RG7204. J Transl Med. (in press)
    • (2010) J Transl Med.
    • Søndergaard, J.N.1    Nazarian, R.2    Qi, W.3
  • 16
    • 33744991550 scopus 로고    scopus 로고
    • Analysis of ribonucleotide reductase M2 mRNA levels in patient samples after GTI-2040 antisense drug treatment
    • Juhasz A, Vassilakos A, Chew HK et al. (2006) Analysis of ribonucleotide reductase M2 mRNA levels in patient samples after GTI-2040 antisense drug treatment. Oncol Rep 15:1299-304
    • (2006) Oncol Rep , vol.15 , pp. 1299-1304
    • Juhasz, A.1    Vassilakos, A.2    Chew, H.K.3
  • 17
    • 0038615898 scopus 로고    scopus 로고
    • GTI-2040, an antisense agent targeting the small subunit component (R2) of human ribonucleotide reductase, shows potent antitumor activity against a variety of tumors
    • Lee Y, Vassilakos A, Feng N et al. (2003) GTI-2040, an antisense agent targeting the small subunit component (R2) of human ribonucleotide reductase, shows potent antitumor activity against a variety of tumors. Cancer Research 63:2802-11
    • (2003) Cancer Research , vol.63 , pp. 2802-2811
    • Lee, Y.1    Vassilakos, A.2    Feng, N.3
  • 18
    • 3042595897 scopus 로고    scopus 로고
    • Stable suppression of the R2 subunit of ribonucleotide reductase by R2-targeted short interference RNA sensitizes p53(-/-) HCT-116 colon cancer cells to DNA-damaging agents and ribonucleotide reductase inhibitors
    • Lin ZP, Belcourt MF, Cory JG et al. (2004) Stable suppression of the R2 subunit of ribonucleotide reductase by R2-targeted short interference RNA sensitizes p53(-/-) HCT-116 colon cancer cells to DNA-damaging agents and ribonucleotide reductase inhibitors. J Biol Chem 279:27030-8
    • (2004) J Biol Chem , vol.279 , pp. 27030-27038
    • Lin, Z.P.1    Belcourt, M.F.2    Cory, J.G.3
  • 19
    • 35648934994 scopus 로고    scopus 로고
    • Temozolomide induces senescence but not apoptosis in human melanoma cells
    • Mhaidat NM, Zhang XD, Allen J et al. (2007) Temozolomide induces senescence but not apoptosis in human melanoma cells. Br J Cancer 97:1225-33
    • (2007) Br J Cancer , vol.97 , pp. 1225-1233
    • Mhaidat, N.M.1    Zhang, X.D.2    Allen, J.3
  • 21
    • 76749122345 scopus 로고    scopus 로고
    • Potent subunit-specific effects on cell growth and drug sensitivity from optimised siRNA-mediated silencing of ribonucleotide reductase
    • Reid G, Wallant NC, Patel R et al. (2009) Potent subunit-specific effects on cell growth and drug sensitivity from optimised siRNA-mediated silencing of ribonucleotide reductase. J RNAi Gene Silencing 5:321-30
    • (2009) J RNAi Gene Silencing , vol.5 , pp. 321-330
    • Reid, G.1    Wallant, N.C.2    Patel, R.3
  • 22
    • 44249112125 scopus 로고    scopus 로고
    • Phase II study of extended-dose temozolomide in patients with melanoma
    • Rietschel P, Wolchok JD, Krown S et al. (2008) Phase II study of extended-dose temozolomide in patients with melanoma. J Clin Oncol 26:2299-304
    • (2008) J Clin Oncol , vol.26 , pp. 2299-2304
    • Rietschel, P.1    Wolchok, J.D.2    Krown, S.3
  • 23
    • 33745823841 scopus 로고    scopus 로고
    • Ribonucleotide reductase inhibitors and future drug design
    • Shao J, Zhou B, Chu B et al. (2006) Ribonucleotide reductase inhibitors and future drug design. Curr Cancer Drug Targets 6:409-31
    • (2006) Curr Cancer Drug Targets , vol.6 , pp. 409-431
    • Shao, J.1    Zhou, B.2    Chu, B.3
  • 24


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.