ERK2 small interfering RNAs prevent epidural fibrosis via the efficient inhibition of collagen expression and inflammation in laminectomy rats

Biochemical and Biophysical Research Communications

Volumn 444, Issue 3, 2014, Pages 395-400

  Zhang, Chao ^a   Kong, Xiaohong ^b   Liu, Chang ^b   Liang, Zhipin ^b   Zhao, Huabing ^c   Tong, Wei ^c   Ning, Guangzhi ^a   Shen, Wenyuan ^b   Yao, Liwei ^a   Feng, Shiqing ^a  

^a TIANJIN MEDICAL UNIVERSITY   (China)

^b NANKAI UNIVERSITY   (China)

^c Logistics University   (China)

Author keywords

Adhesion; Epidural fibrosis; ERK2; Laminectomy; Lentivirus; siRNA

Indexed keywords

COLLAGEN; HYDROXYPROLINE; INTERLEUKIN 6; LENTIVIRUS VECTOR; MITOGEN ACTIVATED PROTEIN KINASE 1; SMALL INTERFERING RNA; TRANSFORMING GROWTH FACTOR BETA1; VIMENTIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL DENSITY; CONTROLLED STUDY; DISEASE COURSE; EPIDURAL FIBROSIS; FEMALE; FIBROBLAST; FIBROSIS; GENE EXPRESSION; HISTOPATHOLOGY; HUMAN; HUMAN CELL; INFLAMMATORY CELL; LAMINECTOMY; NONHUMAN; POSTOPERATIVE COMPLICATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; VIRAL GENE DELIVERY SYSTEM;

LENTIVIRUS; RATTUS; RATTUS NORVEGICUS;

ADHESION; EPIDURAL FIBROSIS; ERK2; LAMINECTOMY; LENTIVIRUS; SIRNA;

ANIMALS; COLLAGEN; DOUBLE-BLIND METHOD; EPIDURAL SPACE; FEMALE; FIBROSIS; HYDROXYPROLINE; INFLAMMATION; LAMINECTOMY; RATS; RATS, WISTAR; REAL-TIME POLYMERASE CHAIN REACTION; RNA, SMALL INTERFERING;

EID: 84894074911     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2014.01.070     Document Type: Article

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