SiRNA-loaded multi-shell nanoparticles incorporated into a multilayered film as a reservoir for gene silencing

Biomaterials

Volumn 31, Issue 23, 2010, Pages 6013-6018

  Zhang, Xin ^a,b   Kovtun, Anna ^c   Mendoza Palomares, Carlos ^a,b   Oulad Abdelghani, Mustapha ^d   Fioretti, Florence ^a,b   Rinckenbach, Simon ^a,b   Mainard, Didier ^e   Epple, Matthias ^c   Benkirane Jessel, Nadia ^a,b,e  

^a INSERM   (France)

^b UNIVERSITÉ DE STRASBOURG   (France)

^c UNIVERSITY OF DUISBURG ESSEN   (Germany)

^d CNRS   (France)

^e UNIVERSITY HOSPITAL OF NANCY   (France)

Author keywords

Calcium phosphate; Gene silencing; Nanoparticles; Polyelectrolyte membrane films; Surface modification

Indexed keywords

AMINO ACIDS; CALCIUM PHOSPHATE; GENES; GENETIC ENGINEERING; NANOPARTICLES; POLYELECTROLYTES; PROTON EXCHANGE MEMBRANE FUEL CELLS (PEMFC); SURFACE TREATMENT; SYNTHESIS (CHEMICAL); TISSUE ENGINEERING;

BONE FORMATION; CALCIUM PHOSPHATE NANOPARTICLES; GENE SILENCING; HUMAN OSTEOBLAST; MULTI-LAYERED FILMS; POLYELECTROLYTE MEMBRANES; POLYELECTROLYTE MULTILAYER; SHELL NANOPARTICLES;

MULTILAYERS;

CALCIUM PHOSPHATE; NANOPARTICLE; OSTEOCALCIN; OSTEOPONTIN; POLYELECTROLYTE; POLYLYSINE; SHORT HAIRPIN RNA; SMALL INTERFERING RNA;

ADSORPTION KINETICS; ARTICLE; BIOLOGICAL ACTIVITY; CELL CULTURE; CONTROLLED STUDY; FILM; GENE SILENCING; HUMAN; HUMAN CELL; MATERIAL COATING; OSSIFICATION; OSTEOBLAST; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN SYNTHESIS; TISSUE ENGINEERING; ATOMIC FORCE MICROSCOPY; BIOSYNTHESIS; METABOLISM; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SCANNING ELECTRON MICROSCOPY;

CELLS, CULTURED; GENE SILENCING; HUMANS; MICROSCOPY, ATOMIC FORCE; MICROSCOPY, ELECTRON, SCANNING; NANOPARTICLES; OSTEOBLASTS; OSTEOCALCIN; OSTEOPONTIN; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, SMALL INTERFERING;

EID: 77953809754     PISSN: 01429612     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2010.04.024     Document Type: Article

References (33)

1. Schreier H. The new frontier: gene and oligonucleotide therapy. Pharm Acta Helv 1994, 68(3):145-159.
2. Leung R.K., Whittaker P.A. RNA interference: from gene silencing to gene-specific therapeutics. Pharmacol Ther 2005, 107(2):222-239.
3. Fire A.Z. Gene silencing by double-stranded RNA. Angew Chem Int Ed 2007, 46(37):6966-6984.
4. Kurreck J. RNA interference: from basic research to therapeutic applications. Angew Chem Int Ed 2009, 48(8):1378-1398.
5. Manjunath N., Wu H., Subramanya S., Shankar P. Lentiviral delivery of short hairpin RNAs. Adv Drug Deliv Rev 2009, 61(9):732-745.
6. Tripathy S.K., Black H.B., Goldwasser E., Leiden J.M. Immune responses to transgene-encoded proteins limit the stability of gene expression after injection of replication-defective adenovirus. Nat Med 1996, 2(5):545-550.
7. Van den Haute C., Eggermont K., Nuttin B., Debyser Z., Baekelandt V. Lentiviral vector-mediated delivery of short hairpin RNA results in persistent knockdown of gene expression in mouse brain. Hum Gene Ther 2003, 14(18):1799-1801.
8. Chirila T.V., Rakoczy P.E., Garrett K.L., Lou X., Constable I.J. The use of synthetic polymers for delivery of therapeutic antisense oligodeoxynucleotides. Biomaterials 2002, 23(2):321-342.
9. Gill J.S., Zhu X., Moore M.J., Lu L., Yaszemski M.J., Windebank A.J. Effects of NFkappaB decoy oligonucleotides released from biodegradable polymer microparticles on a glioblastoma cell line. Biomaterials 2002, 23(13):2773-2781.
10. Zohra F.T., Chowdhury E.H., Akaike T. High performance mRNA transfection through carbonate apatite-cationic liposome conjugates. Biomaterials 2009, 30(23-24):4006-4013.
11. McNeil S.E., Perrie Y. Expert Opin Ther Pat 2006, 16:1371-1382.
12. Rea J.C., Gibly R.F., Barron A.E., Shea L.D. Self-assembling peptide-lipoplexes for substrate-mediated gene delivery. Acta Biomater 2009, 5(3):903-912.
13. Moore N.M., Sheppard C.L., Sakiyama-Elbert S.E. Characterization of a multifunctional PEG-based gene delivery system containing nuclear localization signals and endosomal escape peptides. Acta Biomater 2009, 5(3):854-864.
14. Sokolova V., Epple M. Inorganic nanoparticles as carriers of nucleic acids into cells. Angew Chem Int Ed 2008, 47(8):1382-1395.
15. Kovtun A., Heumann R., Epple M. Calcium phosphate nanoparticles for the transfection of cells. Biomed Mater Eng 2009, 19(2-3):241-247.
16. Sokolova V.V., Radtke I., Heumann R., Epple M. Effective transfection of cells with multi-shell calcium phosphate-DNA nanoparticles. Biomaterials 2006, 27(16):3147-3153.
17. Sokolova V., Kovtun A., Prymak O., Meyer-Zaika W., Kubareva E.A., Romanova E.A., et al. Functionalisation of calcium phosphate nanoparticles by oligonucleotides and their application for gene silencing. J Mater Chem 2007, 17(8):721-727.
18. Epple M., Ganesan K., Heumann R., Klesing J., Kovtun A., Neumann S., et al. Application of calcium phosphate nanoparticles in biomedicine. J Mater Chem 2010, 20:18-23.
19. Dorozhkin S.V., Epple M. Biological and medical significance of calcium phosphates. Angew Chem Int Ed 2002, 41(17):3130-3146.
20. Decher G. Fuzzy nanoassemblies: toward layered polymeric multicomposites. Science 1997, 277:1232-1237.
21. Berth G., Voigt A., Dautzenberg H., Donath E., Mohwald H. Polyelectrolyte complexes and layer-by-layer capsules from chitosan/chitosan sulfate. Biomacromolecules 2002, 3(3):579-590.
22. Hiller J., Mendelsohn J.D., Rubner M.F. Reversibly erasable nanoporous anti-reflection coatings from polyelectrolyte multilayers. Nat Mater 2002, 1(1):59-63.
23. Jessel N.B., Schwinte P., Donohue R., Lavalle P., Boulmedais F., Darcy R., et al. Pyridylamino-beta-cyclodextrin as a molecular chaperone for lipopolysaccharide embedded in a multilayered polyelectrolyte architecture. Adv Funct Mater 2004, 14(10):963-969.
24. Lvov Y., Onda M., Ariga K., Kunitake T. Ultrathin films of charged polysaccharides assembled alternately with linear polyions. J Biomater Sci Polym Ed 1998, 9(4):345-355.
25. Sato K., Suzuki I., Anzai J. Preparation of polyelectrolyte-layered assemblies containing cyclodextrin and their binding properties. Langmuir 2003, 19(18):7406-7412.
26. Serizawa T., Yamaguchi M., Akashi M. Enzymatic hydrolysis of a layer-by-layer assembly prepared from chitosan and dextran sulfate. Macromolecules 2002, 35(23):8656-8658.
27. Kempf M., Mandal B., Jilek S., Thiele L., Voros J., Textor M., et al. Improved stimulation of human dendritic cells by receptor engagement with surface-modified microparticles. J Drug Target 2003, 11(1):11-18.
28. Jessel N., Atalar F., Lavalle P., Mutterer J., Decher G., Schaaf P., et al. Bioactive coatings based on a polyelectrolyte multilayer architecture functionalized by embedded proteins. Adv Mater 2003, 15(9):692-695.
29. Mendelsohn J.D., Yang S.Y., Hiller J., Hochbaum A.I., Rubner M.F. Rational design of cytophilic and cytophobic polyelectrolyte multilayer thin films. Biomacromolecules 2003, 4(1):96-106.
30. Jewell C.M., Zhang J., Fredin N.J., Lynn D.M. Multilayered polyelectrolyte films promote the direct and localized delivery of DNA to cells. J Control Release 2005, 106(1-2):214-223.
31. Meyer F., Ball V., Schaaf P., Voegel J.C., Ogier J. Polyplex-embedding in polyelectrolyte multilayers for gene delivery. Biochim Biophys Acta 2006, 1758(3):419-422.
32. Zhang X., Sharma K.K., Boeglin M., Ogier J., Mainard D., Voegel J.C., et al. Transfection ability and intracellular DNA pathway of nanostructured gene-delivery systems. Nano Lett 2008, 8(8):2432-2436.
33. Jessel N., Oulad-Abdeighani M., Meyer F., Lavalle P., Haikel Y., Schaaf P., et al. Multiple and time-scheduled in situ DNA delivery mediated by beta-cyclodextrin embedded in a polyelectrolyte multilayer. Proc Natl Acad Sci U S A 2006, 103(23):8618-8621.