Acellular dermal matrix-based gene therapy augments graft incorporation

Journal of Surgical Research

Volumn 195, Issue 1, 2015, Pages 360-367

  Vandegrift, Meredith T ^a   Szpalski, Caroline ^a   Knobel, Denis ^a   Weinstein, Andrew ^a   Ham, Maria ^a   Ezeamuzie, Obinna ^a   Warren, Stephen M ^a   Saadeh, Pierre B ^a  

^a NEW YORK UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

Acellular dermal matrix; Alloderm; Graft incorporation; Graft vascularity; PHD2; siRNA; Wound healing

Indexed keywords

CYCLINE; CYTOPLASM PROTEIN; FIBROBLAST GROWTH FACTOR 2; HYPOXIA INDUCIBLE FACTOR 1; HYPOXIA INDUCIBLE FACTOR 1ALPHA; PROCOLLAGEN PROLINE 2 OXOGLUTARATE 4 DIOXYGENASE; SMALL INTERFERING RNA; VASCULOTROPIN; EGLN1 PROTEIN, MOUSE; HYPOXIA INDUCIBLE FACTOR PROLINE DIOXYGENASE;

ACELLULAR DERMAL MATRIX; ADULT; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTOFLUORESCENCE; CELL PROLIFERATION; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; HISTOPATHOLOGY; IMMUNOHISTOCHEMISTRY; MALE; MEDICAL PHOTOGRAPHY; NEOVASCULARIZATION (PATHOLOGY); NONHUMAN; NONVIRAL GENE THERAPY; OCCLUSIVE DRESSING; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; STAINING; STROMA CELL; SURGICAL MESH; TISSUE SECTION; VASCULARIZATION; WOUND; WOUND HEALING; ANGIOGENESIS; ANIMAL; ANTAGONISTS AND INHIBITORS; GENE SILENCING; GENE THERAPY; MOUSE; SKIN TRANSPLANTATION;

ACELLULAR DERMIS; ANIMALS; GENE KNOCKDOWN TECHNIQUES; GENETIC THERAPY; HYPOXIA-INDUCIBLE FACTOR-PROLINE DIOXYGENASES; MALE; MICE; NEOVASCULARIZATION, PHYSIOLOGIC; RNA, SMALL INTERFERING; SKIN TRANSPLANTATION;

EID: 84926181664     PISSN: 00224804     EISSN: 10958673     Source Type: Journal    
DOI: 10.1016/j.jss.2015.01.003     Document Type: Article

References (23)

1. J. Leon-Villapalos, M. Eldardiri, and P. Dziewulski The use of human deceased donor skin allograft in burn care Cell Tissue Bank 11 2010 99
2. M.D. Helgeson, B.K. Potter, K.N. Evans, and S.B. Shawen Bioartificial dermal substitute: a preliminary report on its use for the management of complex combat-related soft tissue wounds J Orthop Trauma 21 2007 394
3. A. Langer, and W. Rogowski Systematic review of economic evaluations of human cell-derived wound care products for the treatment of venous leg and diabetic foot ulcers BMC Health Serv Res 9 2009 115
4. S.M. Maurice, and D.A. Skeete Use of human acellular dermal matrix for abdominal wall reconstructions J Surg 197 2009 35
5. K.M. Breuing, and S.M. Warren Immediate bilateral breast reconstruction implants and Inferolateral AlloDerm slings Ann Plast Surg 55 2005 232
6. S.N. Jung, J.W. Chung, Y.M. Yim, and H. Kwon One stage skin grafting of the exposed skull with acellular human dermis (AlloDerm) J Craniofac Surg 19 2008 1660
7. S. Pushpoth, K. Tambe, and S. Sandramouli The use of AlloDerm in the reconstruction of full thickness eyelid defects Orbit 27 2008 337
8. A.K. Wong, B.H. Schonmeyer, P. Singh, D.L. Carlson, S. Li, and B.J. Mehrara Histologic analysis of angiogenesis and lymphangiogenesis in acellular human dermis Plast Reconstr Surg 121 2008 1144
9. Y.S. Chun, K. Verma, and H. Rosen Implant-based breast reconstruction using acellular dermal matrix and the risk of postoperative complications Plast Reconstr Surg 125 2010 429
10. A.K. Antony, C.M. McCarthy, and P.G. Cordeiro Acellular human dermis implantation in 153 immediate two-stage tissue expander breast reconstructions: determining the incidence and significant predictors of complications Plast Reconstr Surg 125 2010 1606
11. V. Rawlani, D.W. Buck, S.A. Johnson, K. Heyer, and J.Y.S. Kim Tissue expander breast reconstruction using pre-hydrated human acellular dermis Ann Plast Surg 2010 In Press
12. J. Bardos, and M. Ashcroft Negative and positive regulation of HIF-1: a complex network Biochemica Biophys Acta 1775 2005 107
13. K. Takeda, A. Cowan, and G.H. Fong Essential role of prolyl hydroxylase domain protein-2 in oxygen homeostasis of the adult vascular system Circulation 116 2007 774
14. I.R. Botusan, V.G. Sunkari, and O. Savu Stabilization of HIF-1alpha is critical to improve wound healing in diabetic mice Proc Natl Acad Sci U S A 105 2008 19426
15. S. Wu, N. Nishiyama, and M. Kano Enhancement of angiogenesis through stabilization of hypoxia-inducible factor-1 by silencing prolyl hydroxylase domain-2 gene Mol Ther 16 2008 1227
16. C. Loinard, A. Ginouvès, and J. Vilar Inhibition of prolyl hydroxylase domain proteins promotes therapeutic revascularization Circulation 120 2009 50
17. K.L. Hefferon Innovations in siRNA research: a technology comes of age Recent Pat Antiinfect Drug Discov 2010 [Epub ahead of print]
18. R. Wadhwa, S.C. Kaul, M. Miyagishi, and K. Taira Know-how of RNA interference and its applications in research and therapy Mutat Res 567 2004 71
19. V.D. Thanik, M.R. Greives, and O.Z. Lerman Topical matrix-based siRNA silences local gene expression in a murine wound model Gene Ther 14 2007 1305
20. http://www.lifecell.com/health-care-professionals/lifecell-products/allodermr-regenerative-tissue-matrix/.
21. B.D. Kelly, S.F. Hackett, and K. Hirota Cell type-specific regulation of angiogenic growth factor gene expression and induction of angiogenesis in nonischemic tissue by a constitutively active form of hypoxia-inducible factor-1 Circ Res 93 2003 1074
22. N.G. Menon, E.D. Rodriguez, and C.K. Byrnes Revascularization of human acellular dermis in full thickness abdominal wall reconstruction in the rabbit model Ann Plast Surg 50 2003 523
23. M.L. Milburn, L.H. Holton, and T.L. Chung Acellular dermal matrix compared with synthetic implant material for repair of ventral hernia in the setting of peri-operative Staphylococcus aureus implant contamination: a rabbit model Surg Infect (Larchmt) 9 2008 433