메뉴 건너뛰기




Volumn 18, Issue 11, 2010, Pages 2018-2027

SiRNA nanoparticle functionalization of nanostructured scaffolds enables controlled multilineage differentiation of stem cells

Author keywords

[No Author keywords available]

Indexed keywords

NANOPARTICLE; PROTEIN BCL W; REPRESSOR PROTEIN; SMALL INTERFERING RNA; TISSUE SCAFFOLD; TRIBBLES HOMOLOG 2 PROTEIN; UNCLASSIFIED DRUG;

EID: 78049465948     PISSN: 15250016     EISSN: 15250024     Source Type: Journal    
DOI: 10.1038/mt.2010.166     Document Type: Article
Times cited : (74)

References (46)
  • 1
    • 0027595948 scopus 로고
    • Tissue engineering
    • Langer, R and Vacanti, JP (1993). Tissue engineering. Science 260: 920-926.
    • (1993) Science , vol.260 , pp. 920-926
    • Langer, R.1    Vacanti, J.P.2
  • 2
    • 33646052556 scopus 로고    scopus 로고
    • Tissue-engineered autologous bladders for patients needing cystoplasty
    • Atala, A, Bauer, SB, Soker, S, Yoo, JJ and Retik, AB (2006). Tissue-engineered autologous bladders for patients needing cystoplasty. Lancet 367: 1241-1246.
    • (2006) Lancet , vol.367 , pp. 1241-1246
    • Atala, A.1    Bauer, S.B.2    Soker, S.3    Yoo, J.J.4    Retik, A.B.5
  • 4
    • 58249093214 scopus 로고    scopus 로고
    • Multi-layered culture of human skin fbroblasts and keratinocytes through three-dimensional freeform fabrication
    • Lee, W, Debasitis, JC, Lee, VK, Lee, JH, Fischer, K, Edminster, K et al. (2009). Multi-layered culture of human skin fbroblasts and keratinocytes through three-dimensional freeform fabrication. Biomaterials 30: 1587-1595.
    • (2009) Biomaterials , vol.30 , pp. 1587-1595
    • Lee, W.1    Debasitis, J.C.2    Lee, V.K.3    Lee, J.H.4    Fischer, K.5    Edminster, K.6
  • 5
    • 38349195609 scopus 로고    scopus 로고
    • Three-dimensional fber deposition of cell-laden, viable, patterned constructs for bone tissue printing
    • Fedorovich, NE, De Wijn, JR, Verbout, AJ, Alblas, J and Dhert, WJ (2008). Three-dimensional fber deposition of cell-laden, viable, patterned constructs for bone tissue printing. Tissue Eng Part A 14: 127-133.
    • (2008) Tissue Eng Part A , vol.14 , pp. 127-133
    • Fedorovich, N.E.1    De Wijn, J.R.2    Verbout, A.J.3    Alblas, J.4    Dhert, W.J.5
  • 7
    • 0029129229 scopus 로고
    • Osteoblast and chondroblast differentiation
    • Aubin, JE, Liu, F, Malaval, L and Gupta, AK (1995). Osteoblast and chondroblast differentiation. Bone 17(2 Suppl): 77S-83S.
    • (1995) Bone , vol.17 , Issue.2 SUPPL.
    • Aubin, J.E.1    Liu, F.2    Malaval, L.3    Gupta, A.K.4
  • 8
    • 0034564242 scopus 로고    scopus 로고
    • Cytokine delivery and tissue engineering
    • Lee, SJ (2000). Cytokine delivery and tissue engineering. Yonsei Med J 41: 704-719.
    • (2000) Yonsei Med J , vol.41 , pp. 704-719
    • Lee, S.J.1
  • 9
    • 23844480941 scopus 로고    scopus 로고
    • Plasmid delivery in vivo from porous tissue-engineering scaffolds: Transgene expression and cellular transfection
    • Jang, JH, Rives, CB and Shea, LD (2005). Plasmid delivery in vivo from porous tissue-engineering scaffolds: transgene expression and cellular transfection. Mol Ther 12: 475-483.
    • (2005) Mol Ther , vol.12 , pp. 475-483
    • Jang, J.H.1    Rives, C.B.2    Shea, L.D.3
  • 10
    • 15444381040 scopus 로고    scopus 로고
    • Bone regeneration in a rat cranial defect with delivery of PEI-condensed plasmid DNA encoding for bone morphogenetic protein-4 (BMP-4)
    • Huang, YC, Simmons, C, Kaigler, D, Rice, KG and Mooney, DJ (2005). Bone regeneration in a rat cranial defect with delivery of PEI-condensed plasmid DNA encoding for bone morphogenetic protein-4 (BMP-4). Gene Ther 12: 418-426.
    • (2005) Gene Ther , vol.12 , pp. 418-426
    • Huang, Y.C.1    Simmons, C.2    Kaigler, D.3    Rice, K.G.4    Mooney, D.J.5
  • 12
    • 1842715778 scopus 로고    scopus 로고
    • Dicers at RISC; The mechanism of RNAi
    • Tijsterman, M and Plasterk, RH (2004). Dicers at RISC; the mechanism of RNAi. Cell 117: 1-3.
    • (2004) Cell , vol.117 , pp. 1-3
    • Tijsterman, M.1    Plasterk, R.H.2
  • 13
    • 37749033958 scopus 로고    scopus 로고
    • Human mesenchymal stem cells: From basic biology to clinical applications
    • Abdallah, BM and Kassem, M (2008). Human mesenchymal stem cells: from basic biology to clinical applications. Gene Ther 15: 109-116.
    • (2008) Gene Ther , vol.15 , pp. 109-116
    • Abdallah, B.M.1    Kassem, M.2
  • 14
    • 34547485288 scopus 로고    scopus 로고
    • A high-throughput siRNA library screen identifes osteogenic suppressors in human mesenchymal stem cells
    • Zhao, Y and Ding, S (2007). A high-throughput siRNA library screen identifes osteogenic suppressors in human mesenchymal stem cells. Proc Natl Acad Sci USA 104: 9673-9678.
    • (2007) Proc Natl Acad Sci USA , vol.104 , pp. 9673-9678
    • Zhao, Y.1    Ding, S.2
  • 16
    • 34548259466 scopus 로고    scopus 로고
    • TRB2, a mouse Tribbles ortholog, suppresses adipocyte differentiation by inhibiting AKT and C/ EBPbeta
    • Naiki, T, Saijou, E, Miyaoka, Y, Sekine, K and Miyajima, A (2007). TRB2, a mouse Tribbles ortholog, suppresses adipocyte differentiation by inhibiting AKT and C/ EBPbeta. J Biol Chem 282: 24075-24082.
    • (2007) J Biol Chem , vol.282 , pp. 24075-24082
    • Naiki, T.1    Saijou, E.2    Miyaoka, Y.3    Sekine, K.4    Miyajima, A.5
  • 17
    • 67650079341 scopus 로고    scopus 로고
    • Menin expression modulates mesenchymal cell commitment to the myogenic and osteogenic lineages
    • Aziz, A, Miyake, T, Engleka, KA, Epstein, JA and McDermott, JC (2009). Menin expression modulates mesenchymal cell commitment to the myogenic and osteogenic lineages. Dev Biol 332: 116-130.
    • (2009) Dev Biol , vol.332 , pp. 116-130
    • Aziz, A.1    Miyake, T.2    Engleka, K.A.3    Epstein, J.A.4    McDermott, J.C.5
  • 18
    • 35648943163 scopus 로고    scopus 로고
    • Hepatic differentiation of human bone marrow-derived UE7T-13 cells: Effects of cytokines and CCN family gene expression
    • Shimomura, T, Yoshida, Y, Sakabe, T, Ishii, K, Gonda, K, Murai, R et al. (2007). Hepatic differentiation of human bone marrow-derived UE7T-13 cells: Effects of cytokines and CCN family gene expression. Hepatol Res 37: 1068-1079.
    • (2007) Hepatol Res , vol.37 , pp. 1068-1079
    • Shimomura, T.1    Yoshida, Y.2    Sakabe, T.3    Ishii, K.4    Gonda, K.5    Murai, R.6
  • 19
    • 44949173148 scopus 로고    scopus 로고
    • NRSF silencing induces neuronal differentiation of human mesenchymal stem cells
    • Yang, Y, Li, Y, Lv, Y, Zhang, S, Chen, L, Bai, C et al. (2008). NRSF silencing induces neuronal differentiation of human mesenchymal stem cells. Exp Cell Res 314: 2257-2265.
    • (2008) Exp Cell Res , vol.314 , pp. 2257-2265
    • Yang, Y.1    Li, Y.2    Lv, Y.3    Zhang, S.4    Chen, L.5    Bai, C.6
  • 20
    • 34249306597 scopus 로고    scopus 로고
    • Regulation and guidance of cell behavior for tissue regeneration via the siRNA mechanism
    • Cheema, SK, Chen, E, Shea, LD and Mathur, AB (2007). Regulation and guidance of cell behavior for tissue regeneration via the siRNA mechanism. Wound Repair Regen 15: 286-295.
    • (2007) Wound Repair Regen , vol.15 , pp. 286-295
    • Cheema, S.K.1    Chen, E.2    Shea, L.D.3    Mathur, A.B.4
  • 21
    • 58549084364 scopus 로고    scopus 로고
    • Antisense makes sense in engineered regenerative medicine
    • Yao, Y, Wang, C, Varshney, RR and Wang, DA (2009). Antisense makes sense in engineered regenerative medicine. Pharm Res 26: 263-275.
    • (2009) Pharm Res , vol.26 , pp. 263-275
    • Yao, Y.1    Wang, C.2    Varshney, R.R.3    Wang, D.A.4
  • 23
    • 0035984714 scopus 로고    scopus 로고
    • Telomerase expression extends the proliferative life-span and maintains the osteogenic potential of human bone marrow stromal cells
    • Simonsen, JL, Rosada, C, Serakinci, N, Justesen, J, Stenderup, K, Rattan, SI et al. (2002). Telomerase expression extends the proliferative life-span and maintains the osteogenic potential of human bone marrow stromal cells. Nat Biotechnol 20: 592-596.
    • (2002) Nat Biotechnol , vol.20 , pp. 592-596
    • Simonsen, J.L.1    Rosada, C.2    Serakinci, N.3    Justesen, J.4    Stenderup, K.5    Rattan, S.I.6
  • 24
    • 16244377132 scopus 로고    scopus 로고
    • Tissue distribution and engraftment of human mesenchymal stem cells immortalized by human telomerase reverse transcriptase gene
    • Bentzon, JF, Stenderup, K, Hansen, FD, Schroder, HD, Abdallah, BM, Jensen, TG et al. (2005). Tissue distribution and engraftment of human mesenchymal stem cells immortalized by human telomerase reverse transcriptase gene. Biochem Biophys Res Commun 330: 633-640.
    • (2005) Biochem Biophys Res Commun , vol.330 , pp. 633-640
    • Bentzon, J.F.1    Stenderup, K.2    Hansen, F.D.3    Schroder, H.D.4    Abdallah, B.M.5    Jensen, T.G.6
  • 25
    • 0002969423 scopus 로고    scopus 로고
    • Porous biodegradable polymeric scaffolds prepared by thermally induced phase separation
    • Nam, YS and Park, TG (1999). Porous biodegradable polymeric scaffolds prepared by thermally induced phase separation. J Biomed Mater Res 47: 8-17.
    • (1999) J Biomed Mater Res , vol.47 , pp. 8-17
    • Nam, Y.S.1    Park, T.G.2
  • 26
    • 0347760318 scopus 로고    scopus 로고
    • Decreased fbroblast cell density on chemically degraded poly-lactic-co-glycolic acid, polyurethane, and polycaprolactone
    • Vance, RJ, Miller, DC, Thapa, A, Haberstroh, KM and Webster, TJ (2004). Decreased fbroblast cell density on chemically degraded poly-lactic-co-glycolic acid, polyurethane, and polycaprolactone. Biomaterials 25: 2095-2103.
    • (2004) Biomaterials , vol.25 , pp. 2095-2103
    • Vance, R.J.1    Miller, D.C.2    Thapa, A.3    Haberstroh, K.M.4    Webster, T.J.5
  • 27
    • 67649948772 scopus 로고    scopus 로고
    • Localized and sustained delivery of silencing RNA from macroscopic biopolymer hydrogels
    • Krebs, MD, Jeon, O and Alsberg, E (2009). Localized and sustained delivery of silencing RNA from macroscopic biopolymer hydrogels. J Am Chem Soc 131: 9204-9206.
    • (2009) J Am Chem Soc , vol.131 , pp. 9204-9206
    • Krebs, M.D.1    Jeon, O.2    Alsberg, E.3
  • 28
    • 35548950280 scopus 로고    scopus 로고
    • RNA interference in human foreskin fbroblasts within the three-dimensional collagen matrix
    • Carlson, MA, Prall, AK and Gums, JJ (2007). RNA interference in human foreskin fbroblasts within the three-dimensional collagen matrix. Mol Cell Biochem 306: 123-132.
    • (2007) Mol Cell Biochem , vol.306 , pp. 123-132
    • Carlson, M.A.1    Prall, A.K.2    Gums, J.J.3
  • 30
    • 22544463394 scopus 로고    scopus 로고
    • Role of integrin-linked kinase in regulating phosphorylation of Akt and fbroblast survival in type i collagen matrices through a beta1 integrin viability signaling pathway
    • Nho, RS, Xia, H, Kahm, J, Kleidon, J, Diebold, D and Henke, CA (2005). Role of integrin-linked kinase in regulating phosphorylation of Akt and fbroblast survival in type I collagen matrices through a beta1 integrin viability signaling pathway. J Biol Chem 280: 26630-26639.
    • (2005) J Biol Chem , vol.280 , pp. 26630-26639
    • Nho, R.S.1    Xia, H.2    Kahm, J.3    Kleidon, J.4    Diebold, D.5    Henke, C.A.6
  • 31
    • 0033017213 scopus 로고    scopus 로고
    • DNA delivery from polymer matrices for tissue engineering
    • Shea, LD, Smiley, E, Bonadio, J and Mooney, DJ (1999). DNA delivery from polymer matrices for tissue engineering. Nat Biotechnol 17: 551-554.
    • (1999) Nat Biotechnol , vol.17 , pp. 551-554
    • Shea, L.D.1    Smiley, E.2    Bonadio, J.3    Mooney, D.J.4
  • 33
    • 60049089373 scopus 로고    scopus 로고
    • Development of a novel method for formulating stable siRNA-loaded lipid particles for in vivo use
    • Wu, SY, Putral, LN, Liang, M, Chang, HI, Davies, NM and McMillan, NA (2009). Development of a novel method for formulating stable siRNA-loaded lipid particles for in vivo use. Pharm Res 26: 512-522.
    • (2009) Pharm Res , vol.26 , pp. 512-522
    • Wu, S.Y.1    Putral, L.N.2    Liang, M.3    Chang, H.I.4    Davies, N.M.5    McMillan, N.A.6
  • 34
    • 33645451483 scopus 로고    scopus 로고
    • Mutagenesis and oncogenesis by chromosomal insertion of gene transfer vectors
    • Baum, C, Kustikova, O, Modlich, U, Li, Z and Fehse, B (2006). Mutagenesis and oncogenesis by chromosomal insertion of gene transfer vectors. Hum Gene Ther 17: 253-263.
    • (2006) Hum Gene Ther , vol.17 , pp. 253-263
    • Baum, C.1    Kustikova, O.2    Modlich, U.3    Li, Z.4    Fehse, B.5
  • 35
    • 0033579358 scopus 로고    scopus 로고
    • Gene therapy death prompts review of adenovirus vector
    • Marshal E (1999). Gene Therapy Death Prompts Review of Adenovirus Vector. Science 286: 2244-2245.
    • (1999) Science , vol.286 , pp. 2244-2245
    • Marshal, E.1
  • 37
    • 34748924120 scopus 로고    scopus 로고
    • TRB3 blocks adipocyte differentiation through the inhibition of C/EBPbeta transcriptional activity
    • Bezy, O, Vernochet, C, Gesta, S, Farmer, SR and Kahn, CR (2007). TRB3 blocks adipocyte differentiation through the inhibition of C/EBPbeta transcriptional activity. Mol Cell Biol 27: 6818-6831.
    • (2007) Mol Cell Biol , vol.27 , pp. 6818-6831
    • Bezy, O.1    Vernochet, C.2    Gesta, S.3    Farmer, S.R.4    Kahn, C.R.5
  • 38
    • 44949098710 scopus 로고    scopus 로고
    • TRB3 suppresses adipocyte differentiation by negatively regulating PPARgamma transcriptional activity
    • Takahashi, Y, Ohoka, N, Hayashi, H and Sato, R (2008). TRB3 suppresses adipocyte differentiation by negatively regulating PPARgamma transcriptional activity. J Lipid Res 49: 880-892.
    • (2008) J Lipid Res , vol.49 , pp. 880-892
    • Takahashi, Y.1    Ohoka, N.2    Hayashi, H.3    Sato, R.4
  • 39
    • 34447525145 scopus 로고    scopus 로고
    • Adipocyte differentiation induced using nonspecifc siRNA controls in cultured human mesenchymal stem cells
    • Xu, Y, Mirmalek-Sani, SH, Lin, F, Zhang, J and Oreffo, RO (2007). Adipocyte differentiation induced using nonspecifc siRNA controls in cultured human mesenchymal stem cells. RNA 13: 1179-1183.
    • (2007) RNA , vol.13 , pp. 1179-1183
    • Xu, Y.1    Mirmalek-Sani, S.H.2    Lin, F.3    Zhang, J.4    Oreffo, R.O.5
  • 40
    • 66049138420 scopus 로고    scopus 로고
    • Functional profling reveals critical role for miRNA in differentiation of human mesenchymal stem cells
    • Schoolmeesters, A, Eklund, T, Leake, D, Vermeulen, A, Smith, Q, Force Aldred, S et al. (2009). Functional profling reveals critical role for miRNA in differentiation of human mesenchymal stem cells. PLoS ONE 4: e5605.
    • (2009) PLoS ONE , vol.4
    • Schoolmeesters, A.1    Eklund, T.2    Leake, D.3    Vermeulen, A.4    Smith, Q.5    Force Aldred, S.6
  • 41
    • 42949093218 scopus 로고    scopus 로고
    • MiR-17-92 cluster accelerates adipocyte differentiation by negatively regulating tumor-suppressor Rb2/ p130
    • Wang, Q, Li, YC, Wang, J, Kong, J, Qi, Y, Quigg, RJ et al. (2008). miR-17-92 cluster accelerates adipocyte differentiation by negatively regulating tumor-suppressor Rb2/ p130. Proc Natl Acad Sci USA 105: 2889-2894.
    • (2008) Proc Natl Acad Sci USA , vol.105 , pp. 2889-2894
    • Wang, Q.1    Li, Y.C.2    Wang, J.3    Kong, J.4    Qi, Y.5    Quigg, R.J.6
  • 42
    • 58649086925 scopus 로고    scopus 로고
    • MiR-17 family miRNAs are expressed during early mammalian development and regulate stem cell differentiation
    • Foshay, KM and Gallicano, GI (2009). miR-17 family miRNAs are expressed during early mammalian development and regulate stem cell differentiation. Dev Biol 326: 431-443.
    • (2009) Dev Biol , vol.326 , pp. 431-443
    • Foshay, K.M.1    Gallicano, G.I.2
  • 43
    • 33646385595 scopus 로고    scopus 로고
    • Molecular mechanism of 1,25-dihydroxyvitamin D3 inhibition of adipogenesis in 3T3-L1 cells
    • Kong, J and Li, YC (2006). Molecular mechanism of 1,25-dihydroxyvitamin D3 inhibition of adipogenesis in 3T3-L1 cells. Am J Physiol Endocrinol Metab 290: E916-E924.
    • (2006) Am J Physiol Endocrinol Metab , vol.290
    • Kong, J.1    Li, Y.C.2
  • 45
    • 56749165070 scopus 로고    scopus 로고
    • Instability of standard PCR reference genes in adipose-derived stem cells during propagation, differentiation and hypoxic exposure
    • Fink, T, Lund, P, Pilgaard, L, Rasmussen, JG, Duroux, M and Zachar, V (2008). Instability of standard PCR reference genes in adipose-derived stem cells during propagation, differentiation and hypoxic exposure. BMC Mol Biol 9: 98.
    • (2008) BMC Mol Biol , vol.9 , pp. 98
    • Fink, T.1    Lund, P.2    Pilgaard, L.3    Rasmussen, J.G.4    Duroux, M.5    Zachar, V.6
  • 46
    • 84934438330 scopus 로고    scopus 로고
    • Assessment of bone formation capacity using in vivo transplantation assays: Procedure and tissue analysis
    • Abdallah, BM, Ditzel, N and Kassem, M (2008). Assessment of bone formation capacity using in vivo transplantation assays: procedure and tissue analysis. Methods Mol Biol 455: 89-100.
    • (2008) Methods Mol Biol , vol.455 , pp. 89-100
    • Abdallah, B.M.1    Ditzel, N.2    Kassem, M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.