메뉴 건너뛰기




Volumn 5, Issue 10, 2015, Pages

DNA damage, DNA repair, aging, and neurodegeneration

Author keywords

[No Author keywords available]

Indexed keywords

CELL NUCLEUS DNA; FREE RADICAL; MITOCHONDRIAL DNA;

EID: 84943302807     PISSN: None     EISSN: 21571422     Source Type: Journal    
DOI: 10.1101/cshperspect.a025130     Document Type: Article
Times cited : (302)

References (172)
  • 2
    • 84896286702 scopus 로고    scopus 로고
    • Overexpression of DNA ligase III in mitochondria protects cells against oxidative stress and improves mitochondrial DNA base excision repair
    • Akbari M, Keijzers G, Maynard S, Scheibye-Knudsen M, Desler C, Hickson ID, Bohr VA. 2014. Overexpression of DNA ligase III in mitochondria protects cells against oxidative stress and improves mitochondrial DNA base excision repair. DNA Repair (Amst) 16: 44-53.
    • (2014) DNA Repair (Amst) , vol.16 , pp. 44-53
    • Akbari, M.1    Keijzers, G.2    Maynard, S.3    Scheibye-Knudsen, M.4    Desler, C.5    Hickson, I.D.6    Bohr, V.A.7
  • 4
    • 33845683300 scopus 로고    scopus 로고
    • Nucleotide excision repair disorders and the balance between cancer and aging
    • Andressoo JO, Hoeijmakers JH, Mitchell JR. 2006. Nucleotide excision repair disorders and the balance between cancer and aging. Cell Cycle 5: 2886-2888.
    • (2006) Cell Cycle , vol.5 , pp. 2886-2888
    • Andressoo, J.O.1    Hoeijmakers, J.H.2    Mitchell, J.R.3
  • 5
    • 43049162175 scopus 로고    scopus 로고
    • RecQ helicases: Guardian angels of the DNA replication fork
    • Bachrati CZ, Hickson ID. 2008. RecQ helicases: Guardian angels of the DNA replication fork. Chromosoma 117: 219-233.
    • (2008) Chromosoma , vol.117 , pp. 219-233
    • Bachrati, C.Z.1    Hickson, I.D.2
  • 7
    • 4544322045 scopus 로고    scopus 로고
    • Free radicals and aging
    • Barja G. 2004. Free radicals and aging. Trends Neurosci 27: 595-600.
    • (2004) Trends Neurosci , vol.27 , pp. 595-600
    • Barja, G.1
  • 10
    • 0035990297 scopus 로고    scopus 로고
    • DNA damage and its processing. Relation to human disease
    • Bohr VA. 2002. DNA damage and its processing. Relation to human disease. J Inherit Metab Dis 25: 215-222.
    • (2002) J Inherit Metab Dis , vol.25 , pp. 215-222
    • Bohr, V.A.1
  • 11
    • 84871671623 scopus 로고    scopus 로고
    • Base excision repair in physiology and pathology of the central nervous system
    • Bosshard M, Markkanen E, van LB. 2012. Base excision repair in physiology and pathology of the central nervous system. Int J Mol Sci 13: 16172-16222.
    • (2012) Int J Mol Sci , vol.13 , pp. 16172-16222
    • Bosshard, M.1    Markkanen, E.2    van, L.B.3
  • 12
    • 38049075962 scopus 로고    scopus 로고
    • Human premature aging,DNA repair and RecQ helicases
    • BroshRMJr, Bohr VA. 2007. Human premature aging,DNA repair and RecQ helicases. Nucleic Acids Res 35: 7527- 7544.
    • (2007) Nucleic Acids Res , vol.35 , pp. 7527-7544
    • Brosh, R.M.1    Bohr, V.A.2
  • 14
    • 84884695279 scopus 로고    scopus 로고
    • Telomere dynamics in mice and humans
    • Calado RT, Dumitriu B. 2013. Telomere dynamics in mice and humans. Semin Hematol 50: 165-174.
    • (2013) Semin Hematol , vol.50 , pp. 165-174
    • Calado, R.T.1    Dumitriu, B.2
  • 15
    • 84896733279 scopus 로고    scopus 로고
    • Mitochondrial dismissal in mammals, from protein degradation to mitophagy
    • Campello S, Strappazzon F, Cecconi F. 2014. Mitochondrial dismissal in mammals, from protein degradation to mitophagy. Biochim Biophys Acta 1837: 451-460.
    • (2014) Biochim Biophys Acta , vol.1837 , pp. 451-460
    • Campello, S.1    Strappazzon, F.2    Cecconi, F.3
  • 16
    • 84873638532 scopus 로고    scopus 로고
    • Aging, cellular senescence, and cancer
    • Campisi J. 2013. Aging, cellular senescence, and cancer. Annu Rev Physiol 75: 685-705.
    • (2013) Annu Rev Physiol , vol.75 , pp. 685-705
    • Campisi, J.1
  • 17
    • 84925848840 scopus 로고    scopus 로고
    • Cell senescence: Role in aging and age-related diseases
    • Campisi J, Robert L. 2014. Cell senescence: Role in aging and age-related diseases. Interdiscip Top Gerontol 39: 45-61.
    • (2014) Interdiscip Top Gerontol , vol.39 , pp. 45-61
    • Campisi, J.1    Robert, L.2
  • 18
    • 64949135819 scopus 로고    scopus 로고
    • Does damage to DNA and other macromolecules play a role in aging? If so, how?
    • Campisi J, Vijg J. 2009. Does damage to DNA and other macromolecules play a role in aging? If so, how? J Gerontol A Biol Sci Med Sci 64: 175-178.
    • (2009) J Gerontol A Biol Sci Med Sci , vol.64 , pp. 175-178
    • Campisi, J.1    Vijg, J.2
  • 20
    • 84903370950 scopus 로고    scopus 로고
    • Base excision DNA repair levels in mitochondrial lysates of Alzheimer's disease
    • Canugovi C, Shamanna RA, Croteau DL, Bohr VA. 2014. Base excision DNA repair levels in mitochondrial lysates of Alzheimer's disease. Neurobiol Aging 35: 1293-1300.
    • (2014) Neurobiol Aging , vol.35 , pp. 1293-1300
    • Canugovi, C.1    Shamanna, R.A.2    Croteau, D.L.3    Bohr, V.A.4
  • 21
    • 80555127284 scopus 로고    scopus 로고
    • Theories and mechanisms of aging
    • Cefalu CA. 2011. Theories and mechanisms of aging. Clin Geriatr Med 27: 491-506.
    • (2011) Clin Geriatr Med , vol.27 , pp. 491-506
    • Cefalu, C.A.1
  • 23
    • 84891484172 scopus 로고    scopus 로고
    • The accumulation of DNA repair defects is the molecular origin of carcinogenesis
    • Cha HJ, Yim H. 2013. The accumulation of DNA repair defects is the molecular origin of carcinogenesis. Tumour Biol 34: 3293-3302.
    • (2013) Tumour Biol , vol.34 , pp. 3293-3302
    • Cha, H.J.1    Yim, H.2
  • 24
    • 0035820667 scopus 로고    scopus 로고
    • Patterns of age-specific means and genetic variances of mortality rates predicted by the mutation- accumulation theory of ageing
    • Charlesworth B. 2001. Patterns of age-specific means and genetic variances of mortality rates predicted by the mutation- accumulation theory of ageing. J Theor Biol 210: 47-65.
    • (2001) J Theor Biol , vol.210 , pp. 47-65
    • Charlesworth, B.1
  • 27
    • 10344256183 scopus 로고    scopus 로고
    • Defective telomere lagging strand synthesis in cells lacking WRN helicase activity
    • Crabbe L, Verdun RE, Haggblom CI, Karlseder J. 2004. Defective telomere lagging strand synthesis in cells lacking WRN helicase activity. Science 306: 1951-1953.
    • (2004) Science , vol.306 , pp. 1951-1953
    • Crabbe, L.1    Verdun, R.E.2    Haggblom, C.I.3    Karlseder, J.4
  • 29
    • 84902187810 scopus 로고    scopus 로고
    • Human RecQ helicases in DNA repair, recombination, and replication
    • Croteau DL, Popuri V, Opresko PL, Bohr VA. 2014. Human RecQ helicases in DNA repair, recombination, and replication. Annu Rev Biochem 83: 519-552.
    • (2014) Annu Rev Biochem , vol.83 , pp. 519-552
    • Croteau, D.L.1    Popuri, V.2    Opresko, P.L.3    Bohr, V.A.4
  • 33
    • 18544375428 scopus 로고    scopus 로고
    • Pathophysiologic role of oxidative stress-induced poly (ADP-ribose) polymerase 1 activation: Focus on cell death and transcriptional regulation
    • Erdelyi K, Bakondi E, Gergely P, Szabo C, Virag L. 2005. Pathophysiologic role of oxidative stress-induced poly (ADP-ribose) polymerase 1 activation: Focus on cell death and transcriptional regulation. Cell Mol Life Sci 62: 751-759.
    • (2005) Cell Mol Life Sci , vol.62 , pp. 751-759
    • Erdelyi, K.1    Bakondi, E.2    Gergely, P.3    Szabo, C.4    Virag, L.5
  • 34
    • 79954419399 scopus 로고    scopus 로고
    • Deciphering the intricate regulatory mechanisms for the cellular choice between cell repair, apoptosis or senescence in response to damaging signals
    • Erol A. 2011. Deciphering the intricate regulatory mechanisms for the cellular choice between cell repair, apoptosis or senescence in response to damaging signals. Cell Signal 23: 1076-1081.
    • (2011) Cell Signal , vol.23 , pp. 1076-1081
    • Erol, A.1
  • 35
    • 0019826665 scopus 로고
    • Establishment in culture of pluripotential cells from mouse embryos
    • Evans MJ, Kaufman MH. 1981. Establishment in culture of pluripotential cells from mouse embryos. Nature 292: 154-156.
    • (1981) Nature , vol.292 , pp. 154-156
    • Evans, M.J.1    Kaufman, M.H.2
  • 36
    • 77955501963 scopus 로고    scopus 로고
    • SIRT1 regulates UV-induced DNA repair through deacetylating XPA
    • Fan W, Luo J. 2010. SIRT1 regulates UV-induced DNA repair through deacetylating XPA. Mol Cell 39: 247-258.
    • (2010) Mol Cell , vol.39 , pp. 247-258
    • Fan, W.1    Luo, J.2
  • 38
    • 84897442012 scopus 로고    scopus 로고
    • Parthanatos: Mitochondrial-linked mechanisms and therapeutic opportunities
    • Fatokun AA, Dawson VL, Dawson TM. 2014. Parthanatos: Mitochondrial-linked mechanisms and therapeutic opportunities. Br J Pharmacol 171: 2000-2016.
    • (2014) Br J Pharmacol , vol.171 , pp. 2000-2016
    • Fatokun, A.A.1    Dawson, V.L.2    Dawson, T.M.3
  • 41
    • 33845518305 scopus 로고    scopus 로고
    • DNA repair in neurons: So if they don't divide what's to repair?
    • Fishel ML, Vasko MR, Kelley MR. 2007. DNA repair in neurons: So if they don't divide what's to repair? Mutat Res 614: 24-36.
    • (2007) Mutat Res , vol.614 , pp. 24-36
    • Fishel, M.L.1    Vasko, M.R.2    Kelley, M.R.3
  • 42
    • 0033617316 scopus 로고    scopus 로고
    • Human Werner syndrome DNA helicase unwinds tetrahelical structures of the fragile X syndrome repeat sequence d(CGG)n
    • Fry M, Loeb LA. 1999. Human Werner syndrome DNA helicase unwinds tetrahelical structures of the fragile X syndrome repeat sequence d(CGG)n. J Biol Chem 274: 12797-12802.
    • (1999) J Biol Chem , vol.274 , pp. 12797-12802
    • Fry, M.1    Loeb, L.A.2
  • 43
  • 46
    • 84892915705 scopus 로고    scopus 로고
    • The free radical theory of aging is dead. Long live the damage theory!
    • Gladyshev VN. 2014. The free radical theory of aging is dead. Long live the damage theory! Antioxid Redox Signal 20: 727-731.
    • (2014) Antioxid Redox Signal , vol.20 , pp. 727-731
    • Gladyshev, V.N.1
  • 47
    • 84864530306 scopus 로고    scopus 로고
    • On the programmed/non-programmed aging controversy
    • Goldsmith TC. 2012. On the programmed/non-programmed aging controversy. Biochemistry (Mosc) 77: 729-732.
    • (2012) Biochemistry (Mosc) , vol.77 , pp. 729-732
    • Goldsmith, T.C.1
  • 49
    • 0036787840 scopus 로고    scopus 로고
    • Cooperation between p53 mutation and high telomerase transgenic expression in spontaneous cancer development
    • Gonzalez-Suarez E, Flores JM, Blasco MA. 2002. Cooperation between p53 mutation and high telomerase transgenic expression in spontaneous cancer development. Mol Cell Biol 22: 7291-7301.
    • (2002) Mol Cell Biol , vol.22 , pp. 7291-7301
    • Gonzalez-Suarez, E.1    Flores, J.M.2    Blasco, M.A.3
  • 50
    • 84934438893 scopus 로고    scopus 로고
    • DNA damage and lamins
    • Gonzalo S. 2014. DNA damage and lamins. Adv Exp Med Biol 773: 377-399.
    • (2014) Adv Exp Med Biol , vol.773 , pp. 377-399
    • Gonzalo, S.1
  • 51
    • 0030691121 scopus 로고    scopus 로고
    • Hierarchical deterioration of body systems in Werner's syndrome: Implications for normal ageing
    • Goto M. 1997. Hierarchical deterioration of body systems in Werner's syndrome: Implications for normal ageing. Mech Ageing Dev 98: 239-254.
    • (1997) Mech Ageing Dev , vol.98 , pp. 239-254
    • Goto, M.1
  • 52
    • 77953348161 scopus 로고    scopus 로고
    • Mitochondrial DNA repair and association with aging-An update
    • Gredilla R, Bohr VA, Stevnsner T. 2010. Mitochondrial DNA repair and association with aging-An update. Exp Gerontol 45: 478-488.
    • (2010) Exp Gerontol , vol.45 , pp. 478-488
    • Gredilla, R.1    Bohr, V.A.2    Stevnsner, T.3
  • 53
    • 84867379842 scopus 로고    scopus 로고
    • Nuclear and mitochondrial DNA repair in selected eukaryotic aging model systems
    • Gredilla R, Garm C, Stevnsner T. 2012. Nuclear and mitochondrial DNA repair in selected eukaryotic aging model systems. Oxid Med Cell Longev 2012: 282438.
    • (2012) Oxid Med Cell Longev , vol.2012
    • Gredilla, R.1    Garm, C.2    Stevnsner, T.3
  • 55
    • 0028557213 scopus 로고
    • Stringent sequence requirements for the formation of human telomeres
    • Hanish JP, Yanowitz JL, de LT. 1994. Stringent sequence requirements for the formation of human telomeres. Proc Natl Acad Sci 91: 8861-8865.
    • (1994) Proc Natl Acad Sci , vol.91 , pp. 8861-8865
    • Hanish, J.P.1    Yanowitz, J.L.2    de, L.T.3
  • 56
    • 0015319592 scopus 로고
    • The biologic clock: The mitochondria?
    • Harman D. 1972. The biologic clock: The mitochondria? J Am Geriatr Soc 20: 145-147.
    • (1972) J Am Geriatr Soc , vol.20 , pp. 145-147
    • Harman, D.1
  • 57
    • 50549218525 scopus 로고
    • The limited in vitro lifetime of human diploid cell strains
    • Hayflick L. 1965. The limited in vitro lifetime of human diploid cell strains. Exp Cell Res 37: 614-636.
    • (1965) Exp Cell Res , vol.37 , pp. 614-636
    • Hayflick, L.1
  • 58
    • 34249672703 scopus 로고    scopus 로고
    • Biological aging is no longer an unsolved problem
    • Hayflick L. 2007. Biological aging is no longer an unsolved problem. Ann NY Acad Sci 1100: 1-13.
    • (2007) Ann NY Acad Sci , vol.1100 , pp. 1-13
    • Hayflick, L.1
  • 59
    • 0029787813 scopus 로고    scopus 로고
    • 8-Hydroxyguanine levels in nuclear DNA and its repair activity in rat organs associatedwith age
    • Hirano T, Yamaguchi R, Asami S, Iwamoto N,Kasai H. 1996. 8-Hydroxyguanine levels in nuclear DNA and its repair activity in rat organs associatedwith age. J Gerontol A Biol Sci Med Sci 51: 303-307.
    • (1996) J Gerontol A Biol Sci Med Sci , vol.51 , pp. 303-307
    • Hirano, T.1    Yamaguchi, R.2    Asami, S.3    Iwamoto, N.4    Kasai, H.5
  • 60
    • 70349859881 scopus 로고    scopus 로고
    • DNA damage, aging, and cancer
    • Hoeijmakers JH. 2009. DNA damage, aging, and cancer. N Engl J Med 361: 1475-1485.
    • (2009) N Engl J Med , vol.361 , pp. 1475-1485
    • Hoeijmakers, J.H.1
  • 61
    • 84925842236 scopus 로고    scopus 로고
    • The commitment of human cells to senescence
    • Holliday R. 2014. The commitment of human cells to senescence. Interdiscip Top Gerontol 39: 1-7.
    • (2014) Interdiscip Top Gerontol , vol.39 , pp. 1-7
    • Holliday, R.1
  • 63
    • 40249084262 scopus 로고    scopus 로고
    • Longevity and resistance to stress correlate with DNA repair capacity in Caenorhabditis elegans
    • Hyun M, Lee J, Lee K, May A, Bohr VA, Ahn B. 2008. Longevity and resistance to stress correlate with DNA repair capacity in Caenorhabditis elegans. Nucleic Acids Res 36: 1380-1389.
    • (2008) Nucleic Acids Res , vol.36 , pp. 1380-1389
    • Hyun, M.1    Lee, J.2    Lee, K.3    May, A.4    Bohr, V.A.5    Ahn, B.6
  • 64
    • 84904751060 scopus 로고    scopus 로고
    • NADþ and sirtuins in aging and disease
    • Imai S, Guarente L. 2014. NADþ and sirtuins in aging and disease. Trends Cell Biol 24: 464-471.
    • (2014) Trends Cell Biol , vol.24 , pp. 464-471
    • Imai, S.1    Guarente, L.2
  • 65
    • 84880586724 scopus 로고    scopus 로고
    • DNA repair mechanisms in dividing and non-dividing cells
    • Iyama T, Wilson DM III. 2013. DNA repair mechanisms in dividing and non-dividing cells. DNA Repair (Amst) 12: 620-636.
    • (2013) DNA Repair (Amst) , vol.12 , pp. 620-636
    • Iyama, T.1    Wilson, D.M.2
  • 68
    • 84861322460 scopus 로고    scopus 로고
    • Modern biological theories of aging
    • Jin K. 2010. Modern biological theories of aging. Aging Dis 1: 72-74.
    • (2010) Aging Dis , vol.1 , pp. 72-74
    • Jin, K.1
  • 69
    • 0029888579 scopus 로고    scopus 로고
    • Non-linear accumulation of 8-hydroxy-20-deoxyguanosine, a marker of oxidized DNA damage, during aging
    • Kaneko T, Tahara S, Matsuo M. 1996. Non-linear accumulation of 8-hydroxy-20-deoxyguanosine, a marker of oxidized DNA damage, during aging. Mutat Res 316: 277- 285.
    • (1996) Mutat Res , vol.316 , pp. 277-285
    • Kaneko, T.1    Tahara, S.2    Matsuo, M.3
  • 70
    • 0033605145 scopus 로고    scopus 로고
    • p53- and ATM-dependent apoptosis induced by telomeres lacking TRF2
    • Karlseder J, Broccoli D, Dai Y, Hardy S, De Lange T. 1999. p53- and ATM-dependent apoptosis induced by telomeres lacking TRF2. Science 283: 1321-1325.
    • (1999) Science , vol.283 , pp. 1321-1325
    • Karlseder, J.1    Broccoli, D.2    Dai, Y.3    Hardy, S.4    De Lange, T.5
  • 71
    • 38049024575 scopus 로고    scopus 로고
    • The role of DNA damage repair in aging of adult stem cells
    • Kenyon J, Gerson SL. 2007. The role of DNA damage repair in aging of adult stem cells. Nucleic Acids Res 35: 7557- 7565.
    • (2007) Nucleic Acids Res , vol.35 , pp. 7557-7565
    • Kenyon, J.1    Gerson, S.L.2
  • 73
    • 13944262937 scopus 로고    scopus 로고
    • Understanding the odd science of aging
    • Kirkwood TB. 2005. Understanding the odd science of aging. Cell 120: 437-447.
    • (2005) Cell , vol.120 , pp. 437-447
    • Kirkwood, T.B.1
  • 74
    • 33646351299 scopus 로고    scopus 로고
    • Mitochondrial DNA deletions are abundant and cause functional impairment in aged human substantia nigra neurons
    • Kraytsberg Y, Kudryavtseva E, McKee AC, Geula C, Kowall NW, Khrapko K. 2006. Mitochondrial DNA deletions are abundant and cause functional impairment in aged human substantia nigra neurons. Nat Genet 38: 518-520.
    • (2006) Nat Genet , vol.38 , pp. 518-520
    • Kraytsberg, Y.1    Kudryavtseva, E.2    McKee, A.C.3    Geula, C.4    Kowall, N.W.5    Khrapko, K.6
  • 75
    • 68449098361 scopus 로고    scopus 로고
    • Werner syndrome resembles normal aging
    • Kyng K, Croteau DL, Bohr VA. 2009. Werner syndrome resembles normal aging. Cell Cycle 8: 2323.
    • (2009) Cell Cycle , vol.8 , pp. 2323
    • Kyng, K.1    Croteau, D.L.2    Bohr, V.A.3
  • 76
    • 84877922143 scopus 로고    scopus 로고
    • The role of mitochondrial DNA mutations and free radicals in disease and ageing
    • Lagouge M, Larsson NG. 2013. The role of mitochondrial DNA mutations and free radicals in disease and ageing. J Intern Med 273: 529-543.
    • (2013) J Intern Med , vol.273 , pp. 529-543
    • Lagouge, M.1    Larsson, N.G.2
  • 77
    • 77957938682 scopus 로고    scopus 로고
    • Somatic mutations of mitochondrial DNA in aging and cancer progression
    • Lee HC, Chang CM, Chi CW. 2010. Somatic mutations of mitochondrial DNA in aging and cancer progression. Ageing Res Rev 9: S47-S58.
    • (2010) Ageing Res Rev , vol.9 , pp. S47-S58
    • Lee, H.C.1    Chang, C.M.2    Chi, C.W.3
  • 78
    • 84857923053 scopus 로고    scopus 로고
    • Measuring genome instability in aging- A mini-review
    • LiW, Vijg J. 2012. Measuring genome instability in aging- A mini-review. Gerontology 58: 129-138.
    • (2012) Gerontology , vol.58 , pp. 129-138
    • Li, W.1    Vijg, J.2
  • 81
    • 0027278557 scopus 로고
    • Instability and decay of the primary structure of DNA
    • Lindahl T. 1993. Instability and decay of the primary structure of DNA. Nature 362: 709-715.
    • (1993) Nature , vol.362 , pp. 709-715
    • Lindahl, T.1
  • 82
    • 84974707421 scopus 로고    scopus 로고
    • Reflections on the theories of aging, of oxidative stress, and of science in general. Is it time to abandon the free radical (oxidative stress) theory of aging?
    • Liochev SI. 2014. Reflections on the theories of aging, of oxidative stress, and of science in general. Is it time to abandon the free radical (oxidative stress) theory of aging? Antioxid Redox Signal doi: 10.1089/ars.2014.5928.
    • (2014) Antioxid Redox Signal
    • Liochev, S.I.1
  • 84
    • 62249117077 scopus 로고    scopus 로고
    • The evolutionary theories of aging revisited-A mini-review
    • Ljubuncic P, Reznick AZ. 2009. The evolutionary theories of aging revisited-A mini-review. Gerontology 55: 205- 216.
    • (2009) Gerontology , vol.55 , pp. 205-216
    • Ljubuncic, P.1    Reznick, A.Z.2
  • 85
    • 12344305124 scopus 로고    scopus 로고
    • Mitochondrial dysfunction and type 2 diabetes
    • Lowell BB, Shulman GI. 2005. Mitochondrial dysfunction and type 2 diabetes. Science 307: 384-387.
    • (2005) Science , vol.307 , pp. 384-387
    • Lowell, B.B.1    Shulman, G.I.2
  • 86
    • 75049083495 scopus 로고    scopus 로고
    • Deletion of Ogg1 DNA glycosylase results in telomere base damage and length alteration in yeast
    • Lu J, Liu Y. 2010. Deletion of Ogg1 DNA glycosylase results in telomere base damage and length alteration in yeast. EMBO J 29: 398-409.
    • (2010) EMBO J , vol.29 , pp. 398-409
    • Lu, J.1    Liu, Y.2
  • 88
    • 33751581731 scopus 로고    scopus 로고
    • The Werner and Bloom syndrome proteins catalyze regression of a model replication fork
    • Machwe A, Xiao L, Groden J, Orren DK. 2006. The Werner and Bloom syndrome proteins catalyze regression of a model replication fork. Biochemistry 45: 13939-13946.
    • (2006) Biochemistry , vol.45 , pp. 13939-13946
    • Machwe, A.1    Xiao, L.2    Groden, J.3    Orren, D.K.4
  • 89
    • 33947512416 scopus 로고    scopus 로고
    • Mitochondrial dysfunction in atherosclerosis
    • Madamanchi NR, Runge MS. 2007. Mitochondrial dysfunction in atherosclerosis. Circ Res 100: 460-473.
    • (2007) Circ Res , vol.100 , pp. 460-473
    • Madamanchi, N.R.1    Runge, M.S.2
  • 90
    • 84904324446 scopus 로고    scopus 로고
    • DNA damage and its links to neurodegeneration
    • Madabhushi R, Pan L, Tsai LH. 2014. DNA damage and its links to neurodegeneration. Neuron 83: 266-282.
    • (2014) Neuron , vol.83 , pp. 266-282
    • Madabhushi, R.1    Pan, L.2    Tsai, L.H.3
  • 91
    • 80355129762 scopus 로고    scopus 로고
    • The biology of aging: 1985-2010 and beyond
    • Martin GM. 2011. The biology of aging: 1985-2010 and beyond. FASEB J 25: 3756-3762.
    • (2011) FASEB J , vol.25 , pp. 3756-3762
    • Martin, G.M.1
  • 92
    • 84881656587 scopus 로고    scopus 로고
    • Role of mitochondrial dysfunction and altered autophagy in cardiovascular aging and disease: From mechanisms to therapeutics
    • Marzetti E, Csiszar A, Dutta D, Balagopal G, Calvani R, Leeuwenburgh C. 2013. Role of mitochondrial dysfunction and altered autophagy in cardiovascular aging and disease: From mechanisms to therapeutics. Am J Physiol Heart Circ Physiol 305: H459-H476.
    • (2013) Am J Physiol Heart Circ Physiol , vol.305 , pp. H459-H476
    • Marzetti, E.1    Csiszar, A.2    Dutta, D.3    Balagopal, G.4    Calvani, R.5    Leeuwenburgh, C.6
  • 93
    • 33644796631 scopus 로고    scopus 로고
    • Fibroblasts from long-lived Snell dwarf mice are resistant to oxygen-induced in vitro growth arrest
    • Maynard SP, Miller RA. 2006. Fibroblasts from long-lived Snell dwarf mice are resistant to oxygen-induced in vitro growth arrest. Aging Cell 5: 89-96.
    • (2006) Aging Cell , vol.5 , pp. 89-96
    • Maynard, S.P.1    Miller, R.A.2
  • 96
    • 84891509740 scopus 로고    scopus 로고
    • Relationships between human vitality and mitochondrial respiratory parameters, reactive oxygen species production and dNTP levels in peripheral blood mononuclear cells
    • Maynard S, Keijzers G, Gram M, Desler C, Bendix L, Budtz- Jorgensen E,MolboD, Croteau DL, Osler M, Stevnsner T, et al. 2013. Relationships between human vitality and mitochondrial respiratory parameters, reactive oxygen species production and dNTP levels in peripheral blood mononuclear cells. Aging (Albany NY) 5: 850-864.
    • (2013) Aging (Albany NY) , vol.5 , pp. 850-864
    • Maynard, S.1    Keijzers, G.2    Gram, M.3    Desler, C.4    Bendix, L.5    Budtz-Jorgensen, E.6    Molbo, D.7    Croteau, D.L.8    Osler, M.9    Stevnsner, T.10
  • 98
    • 58549092574 scopus 로고    scopus 로고
    • DNA repair deficiency and neurological disease
    • McKinnon PJ. 2009. DNA repair deficiency and neurological disease. Nat Rev Neurosci 10: 100-112.
    • (2009) Nat Rev Neurosci , vol.10 , pp. 100-112
    • McKinnon, P.J.1
  • 101
    • 1642268993 scopus 로고    scopus 로고
    • The effect of donor age on the processing of UVdamaged DNA by cultured human cells: Reduced DNA repair capacity and increased DNA mutability
    • Moriwaki S, Ray S, Tarone RE, Kraemer KH, Grossman L. 1996. The effect of donor age on the processing of UVdamaged DNA by cultured human cells: Reduced DNA repair capacity and increased DNA mutability.Mutat Res 364: 117-123.
    • (1996) Mutat Res , vol.364 , pp. 117-123
    • Moriwaki, S.1    Ray, S.2    Tarone, R.E.3    Kraemer, K.H.4    Grossman, L.5
  • 104
    • 0031961290 scopus 로고    scopus 로고
    • Increased poly(ADP-ribose) polymerase activity in lymphoblastoid cell lines from centenarians
    • Muiras ML, Muller M, Schachter F, Burkle A. 1998. Increased poly(ADP-ribose) polymerase activity in lymphoblastoid cell lines from centenarians. J Mol Med 76: 346-354.
    • (1998) J Mol Med , vol.76 , pp. 346-354
    • Muiras, M.L.1    Muller, M.2    Schachter, F.3    Burkle, A.4
  • 105
    • 0034092670 scopus 로고    scopus 로고
    • Age and organ dependent spontaneous generation of nuclear 8-hydroxydeoxyguanosine in male Fischer 344 rats
    • Nakae D, Akai H, Kishida H, Kusuoka O, Tsutsumi M, Konishi y. 2000. Age and organ dependent spontaneous generation of nuclear 8-hydroxydeoxyguanosine in male Fischer 344 rats. Lab Invest 80: 249-261.
    • (2000) Lab Invest , vol.80 , pp. 249-261
    • Nakae, D.1    Akai, H.2    Kishida, H.3    Kusuoka, O.4    Tsutsumi, M.5    Konishi, Y.6
  • 106
    • 58149314211 scopus 로고    scopus 로고
    • Parkin is recruited selectively to impaired mitochondria and promotes their autophagy
    • Narendra D, Tanaka A, Suen DF, Youle RJ. 2008. Parkin is recruited selectively to impaired mitochondria and promotes their autophagy. J Cell Biol 183: 795-803.
    • (2008) J Cell Biol , vol.183 , pp. 795-803
    • Narendra, D.1    Tanaka, A.2    Suen, D.F.3    Youle, R.J.4
  • 107
    • 79955014012 scopus 로고    scopus 로고
    • A comprehensive description of the severity groups in Cockayne syndrome
    • Natale V. 2011. A comprehensive description of the severity groups in Cockayne syndrome. Am J Med Genet A 155A: 1081-1095.
    • (2011) Am J Med Genet A , vol.155 A , pp. 1081-1095
    • Natale, V.1
  • 108
    • 79961208665 scopus 로고    scopus 로고
    • Xeroderma pigmentosum and other diseases of human premature aging and DNA repair: Molecules to patients
    • Niedernhofer LJ, Bohr VA, Sander M, Kraemer KH. 2011. Xeroderma pigmentosum and other diseases of human premature aging and DNA repair: Molecules to patients. Mech Ageing Dev 132: 340-347.
    • (2011) Mech Ageing Dev , vol.132 , pp. 340-347
    • Niedernhofer, L.J.1    Bohr, V.A.2    Sander, M.3    Kraemer, K.H.4
  • 109
    • 34247178359 scopus 로고    scopus 로고
    • DNA repair in differentiated cells: Some new answers to old questions
    • Nouspikel T. 2007. DNA repair in differentiated cells: Some new answers to old questions. Neuroscience 145: 1213- 1221.
    • (2007) Neuroscience , vol.145 , pp. 1213-1221
    • Nouspikel, T.1
  • 112
    • 79951997444 scopus 로고    scopus 로고
    • USP47 is a deubiquitylating enzyme that regulates base excision repair by controlling steady-state levels of DNA polymerase β
    • Parsons JL, Dianova II, Khoronenkova SV, Edelmann MJ, Kessler BM, Dianov GL. 2011. USP47 is a deubiquitylating enzyme that regulates base excision repair by controlling steady-state levels of DNA polymerase β. Mol Cell 41: 609-615.
    • (2011) Mol Cell , vol.41 , pp. 609-615
    • Parsons, J.L.1    Dianova, I.I.2    Khoronenkova, S.V.3    Edelmann, M.J.4    Kessler, B.M.5    Dianov, G.L.6
  • 113
    • 38049057905 scopus 로고    scopus 로고
    • DNA damage in telomeres and mitochondria during cellular senescence: Is there a connection?
    • Passos JF, Saretzki G, von Zglinicki T. 2007. DNA damage in telomeres and mitochondria during cellular senescence: Is there a connection? Nucleic Acids Res 35: 7505-7513.
    • (2007) Nucleic Acids Res , vol.35 , pp. 7505-7513
    • Passos, J.F.1    Saretzki, G.2    von Zglinicki, T.3
  • 117
    • 78650419603 scopus 로고    scopus 로고
    • Factors that influence telomeric oxidative base damage and repair by DNA glycosylase OGG1
    • Rhee DB, Ghosh A, Lu J, Bohr VA, Liu Y. 2011. Factors that influence telomeric oxidative base damage and repair by DNA glycosylase OGG1. DNA Repair (Amst) 10: 34-44.
    • (2011) DNA Repair (Amst) , vol.10 , pp. 34-44
    • Rhee, D.B.1    Ghosh, A.2    Lu, J.3    Bohr, V.A.4    Liu, Y.5
  • 118
    • 4444381880 scopus 로고    scopus 로고
    • Transient adenoviral N-methylpurine DNA glycosylase overexpression imparts chemotherapeutic sensitivity to human breast cancer cells
    • Rinne M, Caldwell D, Kelley MR. 2004. Transient adenoviral N-methylpurine DNA glycosylase overexpression imparts chemotherapeutic sensitivity to human breast cancer cells. Mol Cancer Ther 3: 955-967.
    • (2004) Mol Cancer Ther , vol.3 , pp. 955-967
    • Rinne, M.1    Caldwell, D.2    Kelley, M.R.3
  • 119
    • 77954957710 scopus 로고    scopus 로고
    • Genetic, epigenetic and posttranslational mechanisms of aging
    • Robert L, Labat-Robert J, Robert AM. 2010. Genetic, epigenetic and posttranslational mechanisms of aging. Biogerontology 11: 387-399.
    • (2010) Biogerontology , vol.11 , pp. 387-399
    • Robert, L.1    Labat-Robert, J.2    Robert, A.M.3
  • 120
    • 84873130772 scopus 로고    scopus 로고
    • Role of poly(ADP-ribose) polymerase-1 in the removal ofUV-inducedDNA lesions by nucleotide excision repair
    • Robu M, Shah RG, Petitclerc N, Brind'Amour J, Kandan-Kulangara F, Shah GM. 2013. Role of poly(ADP-ribose) polymerase-1 in the removal ofUV-inducedDNA lesions by nucleotide excision repair. Proc Natl Acad Sci 110: 1658-1663.
    • (2013) Proc Natl Acad Sci , vol.110 , pp. 1658-1663
    • Robu, M.1    Shah, R.G.2    Petitclerc, N.3    Brind'Amour, J.4    Kandan-Kulangara, F.5    Shah, G.M.6
  • 121
    • 84872647982 scopus 로고    scopus 로고
    • The role of DNA repair in the pluripotency and differentiation of human stem cells
    • Rocha CR, Lerner LK, Okamoto OK,Marchetto MC,Menck CF. 2013. The role of DNA repair in the pluripotency and differentiation of human stem cells. Mutat Res 752: 25- 35.
    • (2013) Mutat Res , vol.752 , pp. 25-35
    • Rocha, C.R.1    Lerner, L.K.2    Okamoto, O.K.3    Marchetto, M.C.4    Menck, C.F.5
  • 124
    • 34250007142 scopus 로고    scopus 로고
    • Deficiencies in DNA damage repair limit the function of haematopoietic stem cells with age
    • Rossi DJ, Bryder D, Seita J, Nussenzweig A, Hoeijmakers J, Weissman IL. 2007. Deficiencies in DNA damage repair limit the function of haematopoietic stem cells with age. Nature 447: 725-729.
    • (2007) Nature , vol.447 , pp. 725-729
    • Rossi, D.J.1    Bryder, D.2    Seita, J.3    Nussenzweig, A.4    Hoeijmakers, J.5    Weissman, I.L.6
  • 125
    • 70450277835 scopus 로고    scopus 로고
    • Mitochondrial localization of PARP-1 requires interaction with mitofilin and is involved in the maintenance of mitochondrial DNA integrity
    • Rossi MN, Carbone M, Mostocotto C, Mancone C, Tripodi M, Maione R, Amati P. 2009. Mitochondrial localization of PARP-1 requires interaction with mitofilin and is involved in the maintenance of mitochondrial DNA integrity. J Biol Chem 284: 31616-31624.
    • (2009) J Biol Chem , vol.284 , pp. 31616-31624
    • Rossi, M.N.1    Carbone, M.2    Mostocotto, C.3    Mancone, C.4    Tripodi, M.5    Maione, R.6    Amati, P.7
  • 126
    • 76749168005 scopus 로고    scopus 로고
    • Roles of Werner syndrome protein in protection of genome integrity
    • Rossi ML, Ghosh AK, Bohr VA. 2010. Roles of Werner syndrome protein in protection of genome integrity. DNA Repair (Amst) 9: 331-344.
    • (2010) DNA Repair (Amst) , vol.9 , pp. 331-344
    • Rossi, M.L.1    Ghosh, A.K.2    Bohr, V.A.3
  • 127
    • 1642308537 scopus 로고    scopus 로고
    • Poly(ADP-ribosyl) ated chromatin domains: Access granted
    • Rouleau M, Aubin RA, Poirier GG. 2004. Poly(ADP-ribosyl) ated chromatin domains: Access granted. J Cell Sci 117: 815-825.
    • (2004) J Cell Sci , vol.117 , pp. 815-825
    • Rouleau, M.1    Aubin, R.A.2    Poirier, G.G.3
  • 128
    • 84880596255 scopus 로고    scopus 로고
    • DNA strand break repair and neurodegeneration
    • Rulten SL, Caldecott KW. 2013. DNA strand break repair and neurodegeneration. DNA Repair (Amst) 12: 558-567.
    • (2013) DNA Repair (Amst) , vol.12 , pp. 558-567
    • Rulten, S.L.1    Caldecott, K.W.2
  • 131
    • 1842612108 scopus 로고    scopus 로고
    • Mitochondrial oxidative stress causes chromosomal instability of mouse embryonic fibroblasts
    • Samper E, Nicholls DG, Melov S. 2003. Mitochondrial oxidative stress causes chromosomal instability of mouse embryonic fibroblasts. Aging Cell 2: 277-285.
    • (2003) Aging Cell , vol.2 , pp. 277-285
    • Samper, E.1    Nicholls, D.G.2    Melov, S.3
  • 132
    • 8644232705 scopus 로고    scopus 로고
    • Stress defense in murine embryonic stem cells is superior to that of various differentiated murine cells
    • Saretzki G, Armstrong L, Leake A, Lako M, von Zglinicki T. 2004. Stress defense in murine embryonic stem cells is superior to that of various differentiated murine cells. Stem Cells 22: 962-971.
    • (2004) Stem Cells , vol.22 , pp. 962-971
    • Saretzki, G.1    Armstrong, L.2    Leake, A.3    Lako, M.4    von Zglinicki, T.5
  • 135
    • 84905908997 scopus 로고    scopus 로고
    • Contribution of defective mitophagy to the neurodegeneration in DNA repair-deficient disorders
    • Scheibye-Knudsen M, Fang EF, Croteau DL, BohrVA. 2014a. Contribution of defective mitophagy to the neurodegeneration in DNA repair-deficient disorders. Autophagy 10: 1468-1469.
    • (2014) Autophagy , vol.10 , pp. 1468-1469
    • Scheibye-Knudsen, M.1    Fang, E.F.2    Croteau, D.L.3    Bohr, V.A.4
  • 139
    • 0033910956 scopus 로고    scopus 로고
    • Calorie restriction and aging: A life-history analysis
    • Shanley DP, Kirkwood TB. 2000. Calorie restriction and aging: A life-history analysis. Evolution 54: 740-750.
    • (2000) Evolution , vol.54 , pp. 740-750
    • Shanley, D.P.1    Kirkwood, T.B.2
  • 142
    • 84864499620 scopus 로고    scopus 로고
    • RecQ helicases inDNAdouble strand break repair and telomere maintenance
    • Singh DK, Ghosh AK, Croteau DL, Bohr VA. 2011. RecQ helicases inDNAdouble strand break repair and telomere maintenance. Mutat Res 736: 15-24.
    • (2011) Mutat Res , vol.736 , pp. 15-24
    • Singh, D.K.1    Ghosh, A.K.2    Croteau, D.L.3    Bohr, V.A.4
  • 144
    • 45449093552 scopus 로고    scopus 로고
    • The role of Cockayne syndrome group B (CSB) protein in base excision repair and aging
    • Stevnsner T, Muftuoglu M, Aamann MD, Bohr VA. 2008. The role of Cockayne syndrome group B (CSB) protein in base excision repair and aging. Mech Ageing Dev 129: 441-448.
    • (2008) Mech Ageing Dev , vol.129 , pp. 441-448
    • Stevnsner, T.1    Muftuoglu, M.2    Aamann, M.D.3    Bohr, V.A.4
  • 145
    • 0032538453 scopus 로고    scopus 로고
    • The Bloom's syndrome helicase unwinds G4 DNA
    • Sun H, KarowJK, Hickson ID,Maizels N. 1998. The Bloom's syndrome helicase unwinds G4 DNA. J Biol Chem 273: 27587-27592.
    • (1998) J Biol Chem , vol.273 , pp. 27587-27592
    • Sun, H.1    Karow, J.K.2    Hickson, I.D.3    Maizels, N.4
  • 146
    • 79956318142 scopus 로고    scopus 로고
    • Aprataxin localizes to mitochondria and preserves mitochondrial function
    • Sykora P, Croteau DL, Bohr VA,Wilson DMIII. 2011. Aprataxin localizes to mitochondria and preserves mitochondrial function. Proc Natl Acad Sci 108: 7437-7442.
    • (2011) Proc Natl Acad Sci , vol.108 , pp. 7437-7442
    • Sykora, P.1    Croteau, D.L.2    Bohr, V.A.3    Wilson, D.M.4
  • 147
    • 84855521713 scopus 로고    scopus 로고
    • Near-to-perfect homeostasis: Examples of universal aging rule which germline evades
    • Teplyuk NM. 2012. Near-to-perfect homeostasis: Examples of universal aging rule which germline evades. J Cell Biochem 113: 388-396.
    • (2012) J Cell Biochem , vol.113 , pp. 388-396
    • Teplyuk, N.M.1
  • 148
    • 23844483200 scopus 로고    scopus 로고
    • Cooperation of the Cockayne syndrome group B protein and poly(ADP-ribose) polymerase 1 in the response to oxidative stress
    • Thorslund T, von KC, Harrigan JA, Indig FE, Christiansen M, Stevnsner T, Bohr VA. 2005. Cooperation of the Cockayne syndrome group B protein and poly(ADP-ribose) polymerase 1 in the response to oxidative stress. Mol Cell Biol 25: 7625-7636.
    • (2005) Mol Cell Biol , vol.25 , pp. 7625-7636
    • Thorslund, T.1    von, K.C.2    Harrigan, J.A.3    Indig, F.E.4    Christiansen, M.5    Stevnsner, T.6    Bohr, V.A.7
  • 149
    • 43049176659 scopus 로고    scopus 로고
    • DNA repair in murine embryonic stem cells and differentiated cells
    • Tichy ED, Stambrook PJ. 2008. DNA repair in murine embryonic stem cells and differentiated cells. Exp Cell Res 314: 1929-1936.
    • (2008) Exp Cell Res , vol.314 , pp. 1929-1936
    • Tichy, E.D.1    Stambrook, P.J.2
  • 150
    • 78649983748 scopus 로고    scopus 로고
    • Alzheimer's disease: Effects of β-amyloid on mitochondria
    • Tillement L, Lecanu L, Papadopoulos V. 2011. Alzheimer's disease: Effects of β-amyloid on mitochondria. Mitochondrion 11: 13-21.
    • (2011) Mitochondrion , vol.11 , pp. 13-21
    • Tillement, L.1    Lecanu, L.2    Papadopoulos, V.3
  • 152
    • 38449105997 scopus 로고    scopus 로고
    • The aging process and potential interventions to extend life expectancy
    • Tosato M, Zamboni V, Ferrini A, Cesari M. 2007. The aging process and potential interventions to extend life expectancy. Clin Interv Aging 2: 401-412.
    • (2007) Clin Interv Aging , vol.2 , pp. 401-412
    • Tosato, M.1    Zamboni, V.2    Ferrini, A.3    Cesari, M.4
  • 154
    • 22244448679 scopus 로고    scopus 로고
    • The role of base excision repair in the sensitivity and resistance to temozolomide-mediated cell death
    • Trivedi RN, Almeida KH, Fornsaglio JL, Schamus S, Sobol RW. 2005. The role of base excision repair in the sensitivity and resistance to temozolomide-mediated cell death. Cancer Res 65: 6394-6400.
    • (2005) Cancer Res , vol.65 , pp. 6394-6400
    • Trivedi, R.N.1    Almeida, K.H.2    Fornsaglio, J.L.3    Schamus, S.4    Sobol, R.W.5
  • 157
  • 158
    • 46749125376 scopus 로고    scopus 로고
    • Transcriptional control of mitochondrial biogenesis: The central role of PGC-1α
    • Ventura-Clapier R, Garnier A, Veksler V. 2008. Transcriptional control of mitochondrial biogenesis: The central role of PGC-1α. Cardiovasc Res 79: 208-217.
    • (2008) Cardiovasc Res , vol.79 , pp. 208-217
    • Ventura-Clapier, R.1    Garnier, A.2    Veksler, V.3
  • 159
  • 160
    • 45449108592 scopus 로고    scopus 로고
    • The role of DNA damage and repair in aging: Newapproaches to an old problem
    • Vijg J. 2008. The role of DNA damage and repair in aging: Newapproaches to an old problem. Mech Ageing Dev 129: 498-502.
    • (2008) Mech Ageing Dev , vol.129 , pp. 498-502
    • Vijg, J.1
  • 161
    • 84893763469 scopus 로고    scopus 로고
    • Aging genomes: A necessary evil in the logic of life
    • Vijg J. 2014. Aging genomes: A necessary evil in the logic of life. Bioessays 36: 282-292.
    • (2014) Bioessays , vol.36 , pp. 282-292
    • Vijg, J.1
  • 163
    • 0033942779 scopus 로고    scopus 로고
    • Role of oxidative stress in telomere length regulation and replicative senescence
    • von Zglinicki T. 2000. Role of oxidative stress in telomere length regulation and replicative senescence. Ann NY Acad Sci 908: 99-110.
    • (2000) Ann NY Acad Sci , vol.908 , pp. 99-110
    • von Zglinicki, T.1
  • 164
    • 0034992999 scopus 로고    scopus 로고
    • Stress, DNA damage and ageing-An integrative approach
    • von Zglinicki T, Burkle A, Kirkwood TB. 2001. Stress, DNA damage and ageing-An integrative approach. Exp Gerontol 36: 1049-1062.
    • (2001) Exp Gerontol , vol.36 , pp. 1049-1062
    • von Zglinicki, T.1    Burkle, A.2    Kirkwood, T.B.3
  • 165
    • 0033525773 scopus 로고    scopus 로고
    • Mitochondrial diseases in man and mouse
    • Wallace DC. 1999. Mitochondrial diseases in man and mouse. Science 283: 1482-1488.
    • (1999) Science , vol.283 , pp. 1482-1488
    • Wallace, D.C.1
  • 166
  • 167
    • 78650000995 scopus 로고    scopus 로고
    • Selective neuronal vulnerability to oxidative stress in the brain
    • Wang X, Michaelis EK. 2010. Selective neuronal vulnerability to oxidative stress in the brain. Front Aging Neurosci 2: 12.
    • (2010) Front Aging Neurosci , vol.2 , pp. 12
    • Wang, X.1    Michaelis, E.K.2
  • 169
    • 69949098944 scopus 로고    scopus 로고
    • Neuropathology of Cockayne syndrome: Evidence for impaired development, premature aging, and neurodegeneration
    • Weidenheim KM, Dickson DW, Rapin I. 2009. Neuropathology of Cockayne syndrome: Evidence for impaired development, premature aging, and neurodegeneration. Mech Ageing Dev 130: 619-636.
    • (2009) Mech Ageing Dev , vol.130 , pp. 619-636
    • Weidenheim, K.M.1    Dickson, D.W.2    Rapin, I.3
  • 170
    • 33845604556 scopus 로고    scopus 로고
    • DNAdouble-strand break repair: All's well that ends well
    • WymanC,Kanaar R. 2006. DNAdouble-strand break repair: All's well that ends well. Annu Rev Genet 40: 363-383.
    • (2006) Annu Rev Genet , vol.40 , pp. 363-383
    • Wyman, C.1    Kanaar, R.2
  • 172
    • 84865544952 scopus 로고    scopus 로고
    • Mitochondrial fission, fusion, and stress
    • Youle RJ, van der Bliek AM. 2012. Mitochondrial fission, fusion, and stress. Science 337: 1062-1065.
    • (2012) Science , vol.337 , pp. 1062-1065
    • Youle, R.J.1    van der Bliek, A.M.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.