-
1
-
-
76149084859
-
Role of A-type lamins in signaling, transcription and chromatin organization
-
PMID: 20038676; DOI: 10.1083/jcb.200904124
-
Andrés V, Gonzalez JM. Role of A-type lamins in signaling, transcription and chromatin organization. J Cell Biol 2009; 187:945-57; PMID: 20038676; DOI: 10.1083/jcb.200904124.
-
(2009)
J Cell Biol
, vol.187
, pp. 945-957
-
-
Andrés, V.1
Gonzalez, J.M.2
-
2
-
-
7944219648
-
A-type lamins: Guardians of the soma?
-
PMID: 15517000; DOI: 10.1038/ncb1104-062
-
Hutchison CJ, Worman HJ. A-type lamins: guardians of the soma? Nat Cell Biol 2004; 6:1062-7; PMID: 15517000; DOI: 10.1038/ncb1104-062.
-
(2004)
Nat Cell Biol
, vol.6
, pp. 1062-1067
-
-
Hutchison, C.J.1
Worman, H.J.2
-
3
-
-
33646536969
-
Nuclear lamins, diseases and aging
-
PMID: 16632339; DOI: 10.1016/j.ceb.2006.03.007
-
Mattout A, Dechat T, Adam SA, Goldman RD, Gruenbaum Y. Nuclear lamins, diseases and aging. Curr Opin Cell Biol 2006; 18:335-41; PMID: 16632339; DOI: 10.1016/j.ceb.2006.03.007.
-
(2006)
Curr Opin Cell Biol
, vol.18
, pp. 335-341
-
-
Mattout, A.1
Dechat, T.2
Adam, S.A.3
Goldman, R.D.4
Gruenbaum, Y.5
-
4
-
-
77957263769
-
Diseases of the nuclear envelope
-
PMID: 20182615; DOI: 10.1101/cshperspect.a000760
-
Worman HJ, Ostlund C, Wang Y. Diseases of the nuclear envelope. Cold Spring Harb Perspect Biol 2010; 2:760; PMID: 20182615; DOI: 10.1101/cshperspect. a000760.
-
(2010)
Cold Spring Harb Perspect Biol
, vol.2
, pp. 760
-
-
Worman, H.J.1
Ostlund, C.2
Wang, Y.3
-
5
-
-
0027750819
-
Nuclear A-type lamins are differentially expressed in human lung cancer subtypes
-
PMID: 8391215
-
Broers JL, Raymond Y, Rot MK, Kuijpers H, Wagenaar SS, Ramaekers FC. Nuclear A-type lamins are differentially expressed in human lung cancer subtypes. Am J Pathol 1993; 143:211-20; PMID: 8391215.
-
(1993)
Am J Pathol
, vol.143
, pp. 211-220
-
-
Broers, J.L.1
Raymond, Y.2
Rot, M.K.3
Kuijpers, H.4
Wagenaar, S.S.5
Ramaekers, F.C.6
-
6
-
-
67649950336
-
Nuclear lamins: Key regulators of nuclear structure and activities
-
Prokocimer M, Davidovich M, Nissim-Rafinia M, Wiesel-Motiuk N, Bar D, Barkan R, et al. Nuclear lamins: key regulators of nuclear structure and activities. J Cell Mol Med 2009.
-
(2009)
J Cell Mol Med
-
-
Prokocimer, M.1
Davidovich, M.2
Nissim-Rafinia, M.3
Wiesel-Motiuk, N.4
Bar, D.5
Barkan, R.6
-
7
-
-
59149092901
-
Lamin A: A putative colonic epithelial stem cell biomarker which identifies colorectal tumours with a more aggressive phenotype
-
PMID: 19021554; DOI: 10.1042/BST0361350
-
Willis ND, Wilson RG, Hutchison CJ. Lamin A: a putative colonic epithelial stem cell biomarker which identifies colorectal tumours with a more aggressive phenotype. Biochem Soc Trans 2008; 36:1350-3; PMID: 19021554; DOI: 10.1042/BST0361350.
-
(2008)
Biochem Soc Trans
, vol.36
, pp. 1350-1353
-
-
Willis, N.D.1
Wilson, R.G.2
Hutchison, C.J.3
-
8
-
-
0026024912
-
Differential expression of nuclear envelope lamins A and C in human lung cancer cell lines
-
PMID: 1985776
-
Kaufmann SH, Mabry M, Jasti R, Shaper JH. Differential expression of nuclear envelope lamins A and C in human lung cancer cell lines. Cancer Res 1991; 51:581-6; PMID: 1985776.
-
(1991)
Cancer Res
, vol.51
, pp. 581-586
-
-
Kaufmann, S.H.1
Mabry, M.2
Jasti, R.3
Shaper, J.H.4
-
9
-
-
21244491570
-
Inactivation of the lamin A/C gene by CpG island promoter hypermethylation in hematologic malignancies, and its association with poor survival in nodal diffuse large B-cell lymphoma
-
PMID: 15867203; DOI: 10.1200/JCO.2005.11.650
-
Agrelo R, Setien F, Espada J, Artiga MJ, Rodriguez M, Perez-Rosado A, et al. Inactivation of the lamin A/C gene by CpG island promoter hypermethylation in hematologic malignancies, and its association with poor survival in nodal diffuse large B-cell lymphoma. J Clin Oncol 2005; 23:3940-7; PMID: 15867203; DOI: 10.1200/JCO.2005.11.650.
-
(2005)
J Clin Oncol
, vol.23
, pp. 3940-3947
-
-
Agrelo, R.1
Setien, F.2
Espada, J.3
Artiga, M.J.4
Rodriguez, M.5
Perez-Rosado, A.6
-
10
-
-
22544466685
-
Genomic instability in laminopathy-based premature aging
-
PMID: 15980864; DOI: 10.1038/nm1266
-
Liu B, Wang J, Chan KM, Tjia WM, Deng W, Guan X, et al. Genomic instability in laminopathy-based premature aging. Nat Med 2005; 11:780-5; PMID: 15980864; DOI: 10.1038/nm1266.
-
(2005)
Nat Med
, vol.11
, pp. 780-785
-
-
Liu, B.1
Wang, J.2
Chan, K.M.3
Tjia, W.M.4
Deng, W.5
Guan, X.6
-
11
-
-
33646745137
-
Lamin A-dependent nuclear defects in human aging
-
PMID: 16645051; DOI: 10.1126/science.1127168
-
Scaffidi P, Misteli T. Lamin A-dependent nuclear defects in human aging. Science 2006; 312:1059-63; PMID: 16645051; DOI: 10.1126/science.1127168.
-
(2006)
Science
, vol.312
, pp. 1059-1063
-
-
Scaffidi, P.1
Misteli, T.2
-
12
-
-
0026460896
-
Telomere length predicts replicative capacity of human fibroblasts
-
PMID: 1438199; DOI: 10.1073/pnas.89.21.10114
-
Allsopp RC, Vaziri H, Patterson C, Goldstein S, Younglai EV, Futcher AB, et al. Telomere length predicts replicative capacity of human fibroblasts. Proc Natl Acad Sci USA 1992; 89:10114-8; PMID: 1438199; DOI: 10.1073/pnas.89.21. 10114.
-
(1992)
Proc Natl Acad Sci USA
, vol.89
, pp. 10114-10118
-
-
Allsopp, R.C.1
Vaziri, H.2
Patterson, C.3
Goldstein, S.4
Younglai, E.V.5
Futcher, A.B.6
-
13
-
-
67349126486
-
Telomere length in Hutchinson-Gilford progeria syndrome
-
PMID: 19428457; DOI: 10.1016/j.mad.2009.03.001
-
Decker ML, Chavez E, Vulto I, Lansdorp PM. Telomere length in Hutchinson-Gilford progeria syndrome. Mech Ageing Dev 2009; 130:377-83; PMID: 19428457; DOI: 10.1016/j.mad.2009.03.001.
-
(2009)
Mech Ageing Dev
, vol.130
, pp. 377-383
-
-
Decker, M.L.1
Chavez, E.2
Vulto, I.3
Lansdorp, P.M.4
-
14
-
-
33746883839
-
Expression of disease-causing lamin A mutants impairs the formation of DNA repair foci
-
PMID: 16772334; DOI: 10.1242/jcs.03009
-
Manju K, Muralikrishna B, Parnaik VK. Expression of disease-causing lamin A mutants impairs the formation of DNA repair foci. J Cell Sci 2006; 119:2704-14; PMID: 16772334; DOI: 10.1242/jcs.03009.
-
(2006)
J Cell Sci
, vol.119
, pp. 2704-2714
-
-
Manju, K.1
Muralikrishna, B.2
Parnaik, V.K.3
-
15
-
-
74849107200
-
Loss of A-type lamins and genomic instability
-
PMID: 19901537; DOI: 10.4161/cc.8.23.10092
-
Gonzalez-Suarez I, Redwood AB, Gonzalo S. Loss of A-type lamins and genomic instability. Cell Cycle 2009; 8:3860-5; PMID: 19901537; DOI: 10.4161/cc.8.23.10092.
-
(2009)
Cell Cycle
, vol.8
, pp. 3860-3865
-
-
Gonzalez-Suarez, I.1
Redwood, A.B.2
Gonzalo, S.3
-
16
-
-
69249222566
-
Novel roles for A-type lamins in telomere biology and the DNA damage response pathway
-
PMID: 19629036; DOI: 10.1038/emboj.2009.196
-
Gonzalez-Suarez I, Redwood AB, Perkins SM, Vermolen B, Lichtensztejin D, Grotsky DA, et al. Novel roles for A-type lamins in telomere biology and the DNA damage response pathway. EMBO J 2009; 28:2414-27; PMID: 19629036; DOI: 10.1038/emboj.2009.196.
-
(2009)
EMBO J
, vol.28
, pp. 2414-2427
-
-
Gonzalez-Suarez, I.1
Redwood, A.B.2
Perkins, S.M.3
Vermolen, B.4
Lichtensztejin, D.5
Grotsky, D.A.6
-
17
-
-
70350088548
-
Mechanisms of double-strand break repair in somatic mammalian cells
-
PMID: 19772495; DOI: 10.1042/BJ20090942
-
Hartlerode AJ, Scully R. Mechanisms of double-strand break repair in somatic mammalian cells. Biochem J 2009; 423:157-68; PMID: 19772495; DOI: 10.1042/BJ20090942.
-
(2009)
Biochem J
, vol.423
, pp. 157-168
-
-
Hartlerode, A.J.1
Scully, R.2
-
18
-
-
70350504453
-
The DNA-damage response in human biology and disease
-
PMID: 19847258; DOI: 10.1038/nature08467
-
Jackson SP, Bartek J. The DNA-damage response in human biology and disease. Nature 2009; 461:1071-8; PMID: 19847258; DOI: 10.1038/nature08467.
-
(2009)
Nature
, vol.461
, pp. 1071-1078
-
-
Jackson, S.P.1
Bartek, J.2
-
19
-
-
52049098230
-
Comparison of nonhomologous end joining and homologous recombination in human cells
-
Amst PMID: 18675941; DOI: 10.1016/j.dnarep.2008.06.018
-
Mao Z, Bozzella M, Seluanov A, Gorbunova V. Comparison of nonhomologous end joining and homologous recombination in human cells. DNA Repair (Amst) 2008; 7:1765-71; PMID: 18675941; DOI: 10.1016/j.dnarep.2008.06.018.
-
(2008)
DNA Repair
, vol.7
, pp. 1765-1771
-
-
Mao, Z.1
Bozzella, M.2
Seluanov, A.3
Gorbunova, V.4
-
20
-
-
79952114962
-
ATM-independent, high-fidelity nonhomologous end joining predominates in human embryonic stem cells
-
Albany NY
-
Adams BR, Hawkins AJ, Povirk LF, Valerie K. ATM-independent, high-fidelity nonhomologous end joining predominates in human embryonic stem cells. Aging (Albany NY); 2:582-96.
-
Aging
, vol.2
, pp. 582-596
-
-
Adams, B.R.1
Hawkins, A.J.2
Povirk, L.F.3
Valerie, K.4
-
21
-
-
2642570858
-
Mechanisms of DNA double strand break repair and chromosome aberration formation
-
PMID: 15162010; DOI: 10.1159/000077461
-
Iliakis G, Wang H, Perrault AR, Boecker W, Rosidi B, Windhofer F, et al. Mechanisms of DNA double strand break repair and chromosome aberration formation. Cytogenet Genome Res 2004; 104:14-20; PMID: 15162010; DOI: 10.1159/000077461.
-
(2004)
Cytogenet Genome Res
, vol.104
, pp. 14-20
-
-
Iliakis, G.1
Wang, H.2
Perrault, A.R.3
Boecker, W.4
Rosidi, B.5
Windhofer, F.6
-
22
-
-
0034714199
-
Interactions of the DNA ligase IV-XRCC4 complex with DNA ends and the DNA-dependent protein kinase
-
PMID: 10854421; DOI: 10.1074/jbc.M000491200
-
Chen L, Trujillo K, Sung P, Tomkinson AE. Interactions of the DNA ligase IV-XRCC4 complex with DNA ends and the DNA-dependent protein kinase. J Biol Chem 2000; 275:26196-205; PMID: 10854421; DOI: 10.1074/jbc.M000491200.
-
(2000)
J Biol Chem
, vol.275
, pp. 26196-26205
-
-
Chen, L.1
Trujillo, K.2
Sung, P.3
Tomkinson, A.E.4
-
23
-
-
0035870583
-
Genetic evidence for the involvement of DNA ligase IV in the DNA-PK-dependent pathway of non-homologous end joining in mammalian cells
-
PMID: 11292837; DOI: 10.1093/nar/29.8.1653
-
Wang H, Zeng ZC, Perrault AR, Cheng X, Qin W, Iliakis G. Genetic evidence for the involvement of DNA ligase IV in the DNA-PK-dependent pathway of non-homologous end joining in mammalian cells. Nucleic Acids Res 2001; 29:1653-60; PMID: 11292837; DOI: 10.1093/nar/29.8.1653.
-
(2001)
Nucleic Acids Res
, vol.29
, pp. 1653-1660
-
-
Wang, H.1
Zeng, Z.C.2
Perrault, A.R.3
Cheng, X.4
Qin, W.5
Iliakis, G.6
-
24
-
-
66049150672
-
SIRT6 stabilizes DNA-dependent protein kinase at chromatin for DNA double-strand break repair
-
Albany NY PMID: 20157594
-
McCord RA, Michishita E, Hong T, Berber E, Boxer LD, Kusumoto R, et al. SIRT6 stabilizes DNA-dependent protein kinase at chromatin for DNA double-strand break repair. Aging (Albany NY) 2009; 1:109-21; PMID: 20157594.
-
(2009)
Aging
, vol.1
, pp. 109-121
-
-
McCord, R.A.1
Michishita, E.2
Hong, T.3
Berber, E.4
Boxer, L.D.5
Kusumoto, R.6
-
25
-
-
69249217081
-
Sirtuins at the breaking point: SIRT6 in DNA repair
-
Albany NY PMID: 20157593
-
Lombard DB. Sirtuins at the breaking point: SIRT6 in DNA repair. Aging (Albany NY) 2009; 1:12-6; PMID: 20157593.
-
(2009)
Aging
, vol.1
, pp. 12-16
-
-
Lombard, D.B.1
-
26
-
-
0030926490
-
The scid defect results in much slower repair of DNA double-strand breaks but not high levels of residual breaks
-
PMID: 9146698; DOI: 10.2307/3579619
-
Nevaldine B, Longo JA, Hahn PJ. The scid defect results in much slower repair of DNA double-strand breaks but not high levels of residual breaks. Radiat Res 1997; 147:535-40; PMID: 9146698; DOI: 10.2307/3579619.
-
(1997)
Radiat Res
, vol.147
, pp. 535-540
-
-
Nevaldine, B.1
Longo, J.A.2
Hahn, P.J.3
-
27
-
-
11244280890
-
Involvement of poly(ADP-ribose) polymerase-1 and XRCC1/DNA ligase III in an alternative route for DNA double-strand breaks rejoining
-
PMID: 15498778; DOI: 10.1074/jbc.M404524200
-
Audebert M, Salles B, Calsou P. Involvement of poly(ADP-ribose) polymerase-1 and XRCC1/DNA ligase III in an alternative route for DNA double-strand breaks rejoining. J Biol Chem 2004; 279:55117-26; PMID: 15498778; DOI: 10.1074/jbc.M404524200.
-
(2004)
J Biol Chem
, vol.279
, pp. 55117-55126
-
-
Audebert, M.1
Salles, B.2
Calsou, P.3
-
28
-
-
33845657443
-
PARP-1 and Ku compete for repair of DNA double strand breaks by distinct NHEJ pathways
-
PMID: 17088286; DOI: 10.1093/nar/gkl840
-
Wang M, Wu W, Wu W, Rosidi B, Zhang L, Wang H, et al. PARP-1 and Ku compete for repair of DNA double strand breaks by distinct NHEJ pathways. Nucleic Acids Res 2006; 34:6170-82; PMID: 17088286; DOI: 10.1093/nar/gkl840.
-
(2006)
Nucleic Acids Res
, vol.34
, pp. 6170-6182
-
-
Wang, M.1
Wu, W.2
Wu, W.3
Rosidi, B.4
Zhang, L.5
Wang, H.6
-
29
-
-
0042632901
-
Pathways of DNA double-strand break repair during the mammalian cell cycle
-
PMID: 12897142; DOI: 10.1128/ MCB.23.16.5706-15.2003
-
Rothkamm K, Kruger I, Thompson LH, Lobrich M. Pathways of DNA double-strand break repair during the mammalian cell cycle. Mol Cell Biol 2003; 23:5706-15; PMID: 12897142; DOI: 10.1128/ MCB.23.16.5706-15.2003.
-
(2003)
Mol Cell Biol
, vol.23
, pp. 5706-5715
-
-
Rothkamm, K.1
Kruger, I.2
Thompson, L.H.3
Lobrich, M.4
-
30
-
-
6944226229
-
MRE11/RAD50/NBS1: Complex activities
-
PMID: 15309560; DOI: 10.1007/s00412-004-0306-4
-
Assenmacher N, Hopfner KP. MRE11/RAD50/NBS1: complex activities. Chromosoma 2004; 113:157-66; PMID: 15309560; DOI: 10.1007/s00412-004-0306-4.
-
(2004)
Chromosoma
, vol.113
, pp. 157-166
-
-
Assenmacher, N.1
Hopfner, K.P.2
-
31
-
-
36549060102
-
Human CtIP promotes DNA end resection
-
PMID: 17965729; DOI: 10.1038/nature06337
-
Sartori AA, Lukas C, Coates J, Mistrik M, Fu S, Bartek J, et al. Human CtIP promotes DNA end resection. Nature 2007; 450:509-14; PMID: 17965729; DOI: 10.1038/nature06337.
-
(2007)
Nature
, vol.450
, pp. 509-514
-
-
Sartori, A.A.1
Lukas, C.2
Coates, J.3
Mistrik, M.4
Fu, S.5
Bartek, J.6
-
32
-
-
67349246802
-
CtIP-BRCA1 modulates the choice of DNA double-strand-break repair pathway throughout the cell cycle
-
PMID: 19357644; DOI: 10.1038/nature07955
-
Yun MH, Hiom K. CtIP-BRCA1 modulates the choice of DNA double-strand-break repair pathway throughout the cell cycle. Nature 2009; 459:460-3; PMID: 19357644; DOI: 10.1038/nature07955.
-
(2009)
Nature
, vol.459
, pp. 460-463
-
-
Yun, M.H.1
Hiom, K.2
-
33
-
-
43149118369
-
Cell cycle-dependent complex formation of BRCA1.CtIP.MRN is important for DNA double-strand break repair
-
PMID: 18171670; DOI: 10.1074/jbc.M710245200
-
Chen L, Nievera CJ, Lee AY, Wu X. Cell cycle-dependent complex formation of BRCA1.CtIP.MRN is important for DNA double-strand break repair. J Biol Chem 2008; 283:7713-20; PMID: 18171670; DOI: 10.1074/jbc.M710245200.
-
(2008)
J Biol Chem
, vol.283
, pp. 7713-7720
-
-
Chen, L.1
Nievera, C.J.2
Lee, A.Y.3
Wu, X.4
-
34
-
-
33744947315
-
BRCA1 promotes induction of ssDNA by ionizing radiation
-
PMID: 16707442; DOI: 10.1158/0008-5472.CAN-05-3209
-
Schlegel BP, Jodelka FM, Nunez R. BRCA1 promotes induction of ssDNA by ionizing radiation. Cancer Res 2006; 66:5181-9; PMID: 16707442; DOI: 10.1158/0008-5472.CAN-05-3209.
-
(2006)
Cancer Res
, vol.66
, pp. 5181-5189
-
-
Schlegel, B.P.1
Jodelka, F.M.2
Nunez, R.3
-
35
-
-
2442707746
-
53BP1 links DNA damage-response pathways to immunoglobulin heavy chain class-switch recombination
-
PMID: 15077110; DOI: 10.1038/ni1067
-
Manis JP, Morales JC, Xia Z, Kutok JL, Alt FW, Carpenter PB. 53BP1 links DNA damage-response pathways to immunoglobulin heavy chain class-switch recombination. Nat Immunol 2004; 5:481-7; PMID: 15077110; DOI: 10.1038/ni1067.
-
(2004)
Nat Immunol
, vol.5
, pp. 481-487
-
-
Manis, J.P.1
Morales, J.C.2
Xia, Z.3
Kutok, J.L.4
Alt, F.W.5
Carpenter, P.B.6
-
36
-
-
2542463148
-
53BP1 is required for class switch recombination
-
PMID: 15159415; DOI: 10.1083/jcb.200403021
-
Ward IM, Reina-San-Martin B, Olaru A, Minn K, Tamada K, Lau JS, et al. 53BP1 is required for class switch recombination. J Cell Biol 2004; 165:459-64; PMID: 15159415; DOI: 10.1083/jcb.200403021.
-
(2004)
J Cell Biol
, vol.165
, pp. 459-464
-
-
Ward, I.M.1
Reina-San-Martin, B.2
Olaru, A.3
Minn, K.4
Tamada, K.5
Lau, J.S.6
-
37
-
-
57049124828
-
53BP1 facilitates longrange DNA end-joining during V(D)J recombination
-
PMID: 18931658; DOI: 10.1038/nature07476
-
Difilippantonio S, Gapud E, Wong N, Huang CY, Mahowald G, Chen HT, et al. 53BP1 facilitates longrange DNA end-joining during V(D)J recombination. Nature 2008; 456:529-33; PMID: 18931658; DOI: 10.1038/nature07476.
-
(2008)
Nature
, vol.456
, pp. 529-533
-
-
Difilippantonio, S.1
Gapud, E.2
Wong, N.3
Huang, C.Y.4
Mahowald, G.5
Chen, H.T.6
-
38
-
-
57049132043
-
53BP1 promotes non-homologous end joining of telomeres by increasing chromatin mobility
-
PMID: 18931659; DOI: 10.1038/nature07433
-
Dimitrova N, Chen YC, Spector DL, de Lange T. 53BP1 promotes non-homologous end joining of telomeres by increasing chromatin mobility. Nature 2008; 456:524-8; PMID: 18931659; DOI: 10.1038/nature07433.
-
(2008)
Nature
, vol.456
, pp. 524-528
-
-
Dimitrova, N.1
Chen, Y.C.2
Spector, D.L.3
De Lange, T.4
-
39
-
-
77951057068
-
53BP1 regulates DNA resection and the choice between classical and alternative end joining during class switch recombination
-
PMID: 20368578; DOI: 10.1084/jem.20100244
-
Bothmer A, Robbiani DF, Feldhahn N, Gazumyan A, Nussenzweig A, Nussenzweig MC. 53BP1 regulates DNA resection and the choice between classical and alternative end joining during class switch recombination. J Exp Med 2010; 207:855-65; PMID: 20368578; DOI: 10.1084/jem.20100244.
-
(2010)
J Exp Med
, vol.207
, pp. 855-865
-
-
Bothmer, A.1
Robbiani, D.F.2
Feldhahn, N.3
Gazumyan, A.4
Nussenzweig, A.5
Nussenzweig, M.C.6
-
40
-
-
77950958141
-
53BP1 inhibits homologous recombination in Brca1-deficient cells by blocking resection of DNA breaks
-
PMID: 20362325; DOI: 10.1016/j.cell.2010.03.012
-
Bunting SF, Callen E, Wong N, Chen HT, Polato F, Gunn A, et al. 53BP1 inhibits homologous recombination in Brca1-deficient cells by blocking resection of DNA breaks. Cell 2010; 141:243-54; PMID: 20362325; DOI: 10.1016/j.cell.2010. 03.012.
-
(2010)
Cell
, vol.141
, pp. 243-254
-
-
Bunting, S.F.1
Callen, E.2
Wong, N.3
Chen, H.T.4
Polato, F.5
Gunn, A.6
-
41
-
-
0032861343
-
Megabase chromatin domains involved in DNA double- Strand breaks in vivo
-
PMID: 10477747; DOI: 10.1083/jcb.146.5.905
-
Rogakou EP, Boon C, Redon C, Bonner WM. Megabase chromatin domains involved in DNA double- strand breaks in vivo. J Cell Biol 1999; 146:905-16; PMID: 10477747; DOI: 10.1083/jcb.146.5.905.
-
(1999)
J Cell Biol
, vol.146
, pp. 905-916
-
-
Rogakou, E.P.1
Boon, C.2
Redon, C.3
Bonner, W.M.4
-
42
-
-
0034739853
-
p53 binding protein 1 (53BP1) is an early participant in the cellular response to DNA double-strand breaks
-
PMID: 11134068; DOI: 10.1083/jcb.151.7.1381
-
Schultz LB, Chehab NH, Malikzay A, Halazonetis TD. p53 binding protein 1 (53BP1) is an early participant in the cellular response to DNA double-strand breaks. J Cell Biol 2000; 151:1381-90; PMID: 11134068; DOI: 10.1083/jcb.151.7. 1381.
-
(2000)
J Cell Biol
, vol.151
, pp. 1381-1390
-
-
Schultz, L.B.1
Chehab, N.H.2
Malikzay, A.3
Halazonetis, T.D.4
-
43
-
-
0025270234
-
Heterogeneity in radiation-induced DNA damage and repair in tumor and normal cells measured using the "comet" assay
-
PMID: 2320728; DOI: 10.2307/3577587
-
Olive PL, Banath JP, Durand RE. Heterogeneity in radiation-induced DNA damage and repair in tumor and normal cells measured using the "comet" assay. Radiat Res 1990; 122:86-94; PMID: 2320728; DOI: 10.2307/3577587.
-
(1990)
Radiat Res
, vol.122
, pp. 86-94
-
-
Olive, P.L.1
Banath, J.P.2
Durand, R.E.3
-
44
-
-
0035136283
-
Nonhomologous end-joining of ionizing radiation- Induced DNA double-stranded breaks in human tumor cells deficient in BRCA1 or BRCA2
-
PMID: 11196174
-
Wang H, Zeng ZC, Bui TA, DiBiase SJ, Qin W, Xia F, et al. Nonhomologous end-joining of ionizing radiation- induced DNA double-stranded breaks in human tumor cells deficient in BRCA1 or BRCA2. Cancer Res 2001; 61:270-7; PMID: 11196174.
-
(2001)
Cancer Res
, vol.61
, pp. 270-277
-
-
Wang, H.1
Zeng, Z.C.2
Bui, T.A.3
DiBiase, S.J.4
Qin, W.5
Xia, F.6
-
45
-
-
77953291328
-
53BP1 loss rescues BRCA1 deficiency and is associated with triple-negative and BRCA-mutated breast cancers
-
PMID: 20453858; DOI: 10.1038/ nsmb.1831
-
Bouwman P, Aly A, Escandell JM, Pieterse M, Bartkova J, van der Gulden H, et al. 53BP1 loss rescues BRCA1 deficiency and is associated with triple-negative and BRCA-mutated breast cancers. Nat Struct Mol Biol 2010; 17:688-95; PMID: 20453858; DOI: 10.1038/ nsmb.1831.
-
(2010)
Nat Struct Mol Biol
, vol.17
, pp. 688-695
-
-
Bouwman, P.1
Aly, A.2
Escandell, J.M.3
Pieterse, M.4
Bartkova, J.5
Van Der Gulden, H.6
-
46
-
-
34347388428
-
BLM helicase-dependent and -independent roles of 53BP1 during replication stress-mediated homologous recombination
-
PMID: 17591918; DOI: 10.1083/jcb.200610051
-
Tripathi V, Nagarjuna T, Sengupta S. BLM helicase-dependent and -independent roles of 53BP1 during replication stress-mediated homologous recombination. J Cell Biol 2007; 178:9-14; PMID: 17591918; DOI: 10.1083/jcb.200610051.
-
(2007)
J Cell Biol
, vol.178
, pp. 9-14
-
-
Tripathi, V.1
Nagarjuna, T.2
Sengupta, S.3
-
47
-
-
27144503470
-
MDC1 interacts with Rad51 and facilitates homologous recombination
-
PMID: 16186822; DOI: 10.1038/nsmb991
-
Zhang J, Ma Z, Treszezamsky A, Powell SN. MDC1 interacts with Rad51 and facilitates homologous recombination. Nat Struct Mol Biol 2005; 12:902-9; PMID: 16186822; DOI: 10.1038/nsmb991.
-
(2005)
Nat Struct Mol Biol
, vol.12
, pp. 902-909
-
-
Zhang, J.1
Ma, Z.2
Treszezamsky, A.3
Powell, S.N.4
-
48
-
-
77953932126
-
The role of RPA2 phosphorylation in homologous recombination in response to replication arrest
-
PMID: 20130019; DOI: 10.1093/carcin/bgq035
-
Shi W, Feng Z, Zhang J, Gonzalez-Suarez I, Vanderwaal RP, Wu X, et al. The role of RPA2 phosphorylation in homologous recombination in response to replication arrest. Carcinogenesis 2010; 31:994-1002; PMID: 20130019; DOI: 10.1093/carcin/bgq035.
-
(2010)
Carcinogenesis
, vol.31
, pp. 994-1002
-
-
Shi, W.1
Feng, Z.2
Zhang, J.3
Gonzalez-Suarez, I.4
Vanderwaal, R.P.5
Wu, X.6
-
49
-
-
0030915139
-
Inactivation of p53 results in high rates of homologous recombination
-
PMID: 9150391; DOI: 10.1038/sj.onc.1201143
-
Mekeel KL, Tang W, Kachnic LA, Luo CM, DeFrank JS, Powell SN. Inactivation of p53 results in high rates of homologous recombination. Oncogene 1997; 14:1847-57; PMID: 9150391; DOI: 10.1038/sj.onc.1201143.
-
(1997)
Oncogene
, vol.14
, pp. 1847-1857
-
-
Mekeel, K.L.1
Tang, W.2
Kachnic, L.A.3
Luo, C.M.4
DeFrank, J.S.5
Powell, S.N.6
-
50
-
-
34047112221
-
Repression of RAD51 gene expression by E2F4/p130 complexes in hypoxia
-
PMID: 17001309; DOI: 10.1038/sj.onc.1210001
-
Bindra RS, Glazer PM. Repression of RAD51 gene expression by E2F4/p130 complexes in hypoxia. Oncogene 2007; 26:2048-57; PMID: 17001309; DOI: 10.1038/sj.onc.1210001.
-
(2007)
Oncogene
, vol.26
, pp. 2048-2057
-
-
Bindra, R.S.1
Glazer, P.M.2
-
51
-
-
76649094290
-
Inhibition of poly(ADP-ribose) polymerase downregulates BRCA1 and RAD51 in a pathway mediated by E2F4 and p130
-
PMID: 20133863; DOI: 10.1073/pnas.0904783107
-
Hegan DC, Lu Y, Stachelek GC, Crosby ME, Bindra RS, Glazer PM. Inhibition of poly(ADP-ribose) polymerase downregulates BRCA1 and RAD51 in a pathway mediated by E2F4 and p130. Proc Natl Acad Sci USA 2010; 107:2201-6; PMID: 20133863; DOI: 10.1073/pnas.0904783107.
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 2201-2206
-
-
Hegan, D.C.1
Lu, Y.2
Stachelek, G.C.3
Crosby, M.E.4
Bindra, R.S.5
Glazer, P.M.6
-
52
-
-
3042829496
-
A-type lamins regulate retinoblastoma protein function by promoting subnuclear localization and preventing proteasomal degradation
-
PMID: 15210943; DOI: 10.1073/pnas.0403250101
-
Johnson BR, Nitta RT, Frock RL, Mounkes L, Barbie DA, Stewart CL, et al. A-type lamins regulate retinoblastoma protein function by promoting subnuclear localization and preventing proteasomal degradation. Proc Natl Acad Sci USA 2004; 101:9677-82; PMID: 15210943; DOI: 10.1073/pnas.0403250101.
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 9677-9682
-
-
Johnson, B.R.1
Nitta, R.T.2
Frock, R.L.3
Mounkes, L.4
Barbie, D.A.5
Stewart, C.L.6
-
53
-
-
0036261707
-
Sensing and repairing DNA double-strand breaks
-
PMID: 12016139; DOI: 10.1093/carcin/23.5.687.
-
Jackson SP. Sensing and repairing DNA double-strand breaks. Carcinogenesis 2002; 23:687-96; PMID: 12016139; DOI: 10.1093/carcin/23.5.687.
-
(2002)
Carcinogenesis
, vol.23
, pp. 687-696
-
-
Jackson, S.P.1
-
54
-
-
0035289717
-
Chromosomal stability and the DNA double-stranded break connection
-
PMID: 11256071; DOI: 10.1038/35056049
-
van Gent DC, Hoeijmakers JH, Kanaar R. Chromosomal stability and the DNA double-stranded break connection. Nat Rev Genet 2001; 2:196-206; PMID: 11256071; DOI: 10.1038/35056049.
-
(2001)
Nat Rev Genet
, vol.2
, pp. 196-206
-
-
Van Gent, D.C.1
Hoeijmakers, J.H.2
Kanaar, R.3
-
55
-
-
77951976271
-
Telomere-dependent and telomere-independent origins of endogenous DNA damage in tumor cells
-
Albany NY PMID: 20157510
-
Nakamura AJ, Redon CE, Bonner WM, Sedelnikova OA. Telomere-dependent and telomere-independent origins of endogenous DNA damage in tumor cells. Aging (Albany NY) 2009; 1:212-8; PMID: 20157510.
-
(2009)
Aging
, vol.1
, pp. 212-218
-
-
Nakamura, A.J.1
Redon, C.E.2
Bonner, W.M.3
Sedelnikova, O.A.4
-
56
-
-
79957974187
-
Homologous recombination repair is essential for repair of vosaroxin-induced DNA double-strand breaks
-
Hawtin RE, Stockett DE, Wong OK, Lundin C, Helleday T, Fox JA. Homologous recombination repair is essential for repair of vosaroxin-induced DNA double-strand breaks. Oncotarget 1:606-19.
-
Oncotarget
, vol.1
, pp. 606-619
-
-
Hawtin, R.E.1
Stockett, D.E.2
Wong, O.K.3
Lundin, C.4
Helleday, T.5
Fox, J.A.6
-
57
-
-
77951977367
-
Endogenous DNA breaks: GammaH2AX and the role of telomeres
-
Albany NY
-
Olive PL. Endogenous DNA breaks: gammaH2AX and the role of telomeres. Aging (Albany NY) 2009; 1:154-6; PMID: 20157507.
-
(2009)
Aging
, vol.1
-
-
Olive, P.L.1
-
58
-
-
55549134278
-
Tethering by lamin A stabilizes and targets the ING1 tumour suppressor
-
PMID: 18836436; DOI: 10.1038/ncb1792
-
Han X, Feng X, Rattner JB, Smith H, Bose P, Suzuki K, et al. Tethering by lamin A stabilizes and targets the ING1 tumour suppressor. Nat Cell Biol 2008; 10:1333-40; PMID: 18836436; DOI: 10.1038/ncb1792.
-
(2008)
Nat Cell Biol
, vol.10
, pp. 1333-1340
-
-
Han, X.1
Feng, X.2
Rattner, J.B.3
Smith, H.4
Bose, P.5
Suzuki, K.6
-
59
-
-
77955419733
-
The function of classical and alternative non-homologous end-joining pathways in the fusion of dysfunctional telomeres
-
Rai R, Zheng H, He H, Luo Y, Multani A, Carpenter PB, Chang S. The function of classical and alternative non-homologous end-joining pathways in the fusion of dysfunctional telomeres. EMBO J 2010.
-
(2010)
EMBO J
-
-
Rai, R.1
Zheng, H.2
He, H.3
Luo, Y.4
Multani, A.5
Carpenter, P.B.6
Chang, S.7
-
60
-
-
38949190562
-
Involvement of xeroderma pigmentosum group A (XPA) in progeria arising from defective maturation of prelamin A
-
PMID: 17848622; DOI: 10.1096/fj.07-8598com
-
Liu Y, Wang Y, Rusinol AE, Sinensky MS, Liu J, Shell SM, et al. Involvement of xeroderma pigmentosum group A (XPA) in progeria arising from defective maturation of prelamin A. FASEB J 2008; 22:603-11; PMID: 17848622; DOI: 10.1096/fj.07-8598com.
-
(2008)
FASEB J
, vol.22
, pp. 603-611
-
-
Liu, Y.1
Wang, Y.2
Rusinol, A.E.3
Sinensky, M.S.4
Liu, J.5
Shell, S.M.6
-
61
-
-
0036578920
-
Defective prelamin A processing and muscular and adipocyte alterations in Zmpste24 metalloproteinase-deficient mice
-
PMID: 11923874
-
Pendás AM, Zhou Z, Cadinanos J, Freije JM, Wang J, Hultenby K, et al. Defective prelamin A processing and muscular and adipocyte alterations in Zmpste24 metalloproteinase-deficient mice. Nat Genet 2002; 31:94-9; PMID: 11923874.
-
(2002)
Nat Genet
, vol.31
, pp. 94-99
-
-
Pendás, A.M.1
Zhou, Z.2
Cadinanos, J.3
Freije, J.M.4
Wang, J.5
Hultenby, K.6
-
62
-
-
42149158389
-
Lamin A/C, laminopathies and premature ageing
-
PMID: 18366013
-
Liu B, Zhou Z. Lamin A/C, laminopathies and premature ageing. Histol Histopathol 2008; 23:747-63; PMID: 18366013.
-
(2008)
Histol Histopathol
, vol.23
, pp. 747-763
-
-
Liu, B.1
Zhou, Z.2
-
63
-
-
69949144385
-
Genomic instability and DNA damage responses in progeria arising from defective maturation of prelamin A
-
Albany NY PMID: 19851476
-
Musich PR, Zou Y. Genomic instability and DNA damage responses in progeria arising from defective maturation of prelamin A. Aging (Albany NY) 2009; 1:28-37; PMID: 19851476.
-
(2009)
Aging
, vol.1
, pp. 28-37
-
-
Musich, P.R.1
Zou, Y.2
-
64
-
-
0033615969
-
Loss of A-type lamin expression compromises nuclear envelope integrity leading to muscular dystrophy
-
PMID: 10579712; DOI: 10.1083/ jcb.147.5.913
-
Sullivan T, Escalante-Alcalde D, Bhatt H, Anver M, Bhat N, Nagashima K, et al. Loss of A-type lamin expression compromises nuclear envelope integrity leading to muscular dystrophy. J Cell Biol 1999; 147:913-20; PMID: 10579712; DOI: 10.1083/ jcb.147.5.913.
-
(1999)
J Cell Biol
, vol.147
, pp. 913-920
-
-
Sullivan, T.1
Escalante-Alcalde, D.2
Bhatt, H.3
Anver, M.4
Bhat, N.5
Nagashima, K.6
-
65
-
-
27644543144
-
The role of the BRCA1 tumor suppressor in DNA double-strand break repair
-
PMID: 16254187; DOI: 10.1158/1541-7786.MCR-05-0192
-
Zhang J, Powell SN. The role of the BRCA1 tumor suppressor in DNA double-strand break repair. Mol Cancer Res 2005; 3:531-9; PMID: 16254187; DOI: 10.1158/1541-7786.MCR-05-0192.
-
(2005)
Mol Cancer Res
, vol.3
, pp. 531-539
-
-
Zhang, J.1
Powell, S.N.2
-
66
-
-
0344375083
-
Lentivirus-delivered stable gene silencing by RNAi in primary cells
-
PMID: 12649500; DOI: 10.1261/rna.2192803
-
Stewart SA, Dykxhoorn DM, Palliser D, Mizuno H, Yu EY, An DS, et al. Lentivirus-delivered stable gene silencing by RNAi in primary cells. RNA 2003; 9:493-501; PMID: 12649500; DOI: 10.1261/rna.2192803.
-
(2003)
RNA
, vol.9
, pp. 493-501
-
-
Stewart, S.A.1
Dykxhoorn, D.M.2
Palliser, D.3
Mizuno, H.4
Yu, E.Y.5
An, D.S.6
-
67
-
-
0025305451
-
Detection of etoposide resistance by measuring DNA damage in individual Chinese hamster cells
-
PMID: 2325148; DOI: 10.1093/jnci/82.9.779
-
Olive PL, Banath JP, Durand RE. Detection of etoposide resistance by measuring DNA damage in individual Chinese hamster cells. J Natl Cancer Inst 1990; 82:779-83; PMID: 2325148; DOI: 10.1093/jnci/82.9.779.
-
(1990)
J Natl Cancer Inst
, vol.82
, pp. 779-783
-
-
Olive, P.L.1
Banath, J.P.2
Durand, R.E.3
-
68
-
-
0034280093
-
Mammalian Ku86 protein prevents telomeric fusions independently of the length of TTAGGG repeats and the G-strand overhang
-
PMID: 11256607; DOI: 10.1093/emboreports/ kvd051
-
Samper E, Goytisolo FA, Slijepcevic P, van Buul PP, Blasco MA. Mammalian Ku86 protein prevents telomeric fusions independently of the length of TTAGGG repeats and the G-strand overhang. EMBO Rep 2000; 1:244-52; PMID: 11256607; DOI: 10.1093/emboreports/ kvd051.
-
(2000)
EMBO Rep
, vol.1
, pp. 244-252
-
-
Samper, E.1
Goytisolo, F.A.2
Slijepcevic, P.3
Van Buul, P.P.4
Blasco, M.A.5
-
69
-
-
34548313955
-
Clonogenic assay of cells in vitro
-
PMID: 17406473; DOI: 10.1038/nprot.2006.339
-
Franken NA, Rodermond HM, Stap J, Haveman J, van Bree C. Clonogenic assay of cells in vitro. Nat Protoc 2006; 1:2315-9; PMID: 17406473; DOI: 10.1038/nprot.2006.339.
-
(2006)
Nat Protoc
, vol.1
, pp. 2315-2319
-
-
Franken, N.A.1
Rodermond, H.M.2
Stap, J.3
Haveman, J.4
Van Bree, C.5
|