메뉴 건너뛰기




Volumn 10, Issue 15, 2011, Pages 2549-2560

A dual role for A-type lamins in DNA double-strand break repair

Author keywords

DNA repair; Homologous recombination; Lamins; Non homologous end joining; Radiosensitivity; Telomeres

Indexed keywords

BRCA1 PROTEIN; LAMIN A; PROTEIN P130; RAD51 PROTEIN; RETINOBLASTOMA PROTEIN; TRANSCRIPTION FACTOR E2F4;

EID: 79961121348     PISSN: 15384101     EISSN: 15514005     Source Type: Journal    
DOI: 10.4161/cc.10.15.16531     Document Type: Article
Times cited : (99)

References (69)
  • 1
    • 76149084859 scopus 로고    scopus 로고
    • Role of A-type lamins in signaling, transcription and chromatin organization
    • PMID: 20038676; DOI: 10.1083/jcb.200904124
    • Andrés V, Gonzalez JM. Role of A-type lamins in signaling, transcription and chromatin organization. J Cell Biol 2009; 187:945-57; PMID: 20038676; DOI: 10.1083/jcb.200904124.
    • (2009) J Cell Biol , vol.187 , pp. 945-957
    • Andrés, V.1    Gonzalez, J.M.2
  • 2
    • 7944219648 scopus 로고    scopus 로고
    • A-type lamins: Guardians of the soma?
    • PMID: 15517000; DOI: 10.1038/ncb1104-062
    • Hutchison CJ, Worman HJ. A-type lamins: guardians of the soma? Nat Cell Biol 2004; 6:1062-7; PMID: 15517000; DOI: 10.1038/ncb1104-062.
    • (2004) Nat Cell Biol , vol.6 , pp. 1062-1067
    • Hutchison, C.J.1    Worman, H.J.2
  • 3
  • 4
    • 77957263769 scopus 로고    scopus 로고
    • Diseases of the nuclear envelope
    • PMID: 20182615; DOI: 10.1101/cshperspect.a000760
    • Worman HJ, Ostlund C, Wang Y. Diseases of the nuclear envelope. Cold Spring Harb Perspect Biol 2010; 2:760; PMID: 20182615; DOI: 10.1101/cshperspect. a000760.
    • (2010) Cold Spring Harb Perspect Biol , vol.2 , pp. 760
    • Worman, H.J.1    Ostlund, C.2    Wang, Y.3
  • 5
    • 0027750819 scopus 로고
    • Nuclear A-type lamins are differentially expressed in human lung cancer subtypes
    • PMID: 8391215
    • Broers JL, Raymond Y, Rot MK, Kuijpers H, Wagenaar SS, Ramaekers FC. Nuclear A-type lamins are differentially expressed in human lung cancer subtypes. Am J Pathol 1993; 143:211-20; PMID: 8391215.
    • (1993) Am J Pathol , vol.143 , pp. 211-220
    • Broers, J.L.1    Raymond, Y.2    Rot, M.K.3    Kuijpers, H.4    Wagenaar, S.S.5    Ramaekers, F.C.6
  • 7
    • 59149092901 scopus 로고    scopus 로고
    • Lamin A: A putative colonic epithelial stem cell biomarker which identifies colorectal tumours with a more aggressive phenotype
    • PMID: 19021554; DOI: 10.1042/BST0361350
    • Willis ND, Wilson RG, Hutchison CJ. Lamin A: a putative colonic epithelial stem cell biomarker which identifies colorectal tumours with a more aggressive phenotype. Biochem Soc Trans 2008; 36:1350-3; PMID: 19021554; DOI: 10.1042/BST0361350.
    • (2008) Biochem Soc Trans , vol.36 , pp. 1350-1353
    • Willis, N.D.1    Wilson, R.G.2    Hutchison, C.J.3
  • 8
    • 0026024912 scopus 로고
    • Differential expression of nuclear envelope lamins A and C in human lung cancer cell lines
    • PMID: 1985776
    • Kaufmann SH, Mabry M, Jasti R, Shaper JH. Differential expression of nuclear envelope lamins A and C in human lung cancer cell lines. Cancer Res 1991; 51:581-6; PMID: 1985776.
    • (1991) Cancer Res , vol.51 , pp. 581-586
    • Kaufmann, S.H.1    Mabry, M.2    Jasti, R.3    Shaper, J.H.4
  • 9
    • 21244491570 scopus 로고    scopus 로고
    • Inactivation of the lamin A/C gene by CpG island promoter hypermethylation in hematologic malignancies, and its association with poor survival in nodal diffuse large B-cell lymphoma
    • PMID: 15867203; DOI: 10.1200/JCO.2005.11.650
    • Agrelo R, Setien F, Espada J, Artiga MJ, Rodriguez M, Perez-Rosado A, et al. Inactivation of the lamin A/C gene by CpG island promoter hypermethylation in hematologic malignancies, and its association with poor survival in nodal diffuse large B-cell lymphoma. J Clin Oncol 2005; 23:3940-7; PMID: 15867203; DOI: 10.1200/JCO.2005.11.650.
    • (2005) J Clin Oncol , vol.23 , pp. 3940-3947
    • Agrelo, R.1    Setien, F.2    Espada, J.3    Artiga, M.J.4    Rodriguez, M.5    Perez-Rosado, A.6
  • 10
    • 22544466685 scopus 로고    scopus 로고
    • Genomic instability in laminopathy-based premature aging
    • PMID: 15980864; DOI: 10.1038/nm1266
    • Liu B, Wang J, Chan KM, Tjia WM, Deng W, Guan X, et al. Genomic instability in laminopathy-based premature aging. Nat Med 2005; 11:780-5; PMID: 15980864; DOI: 10.1038/nm1266.
    • (2005) Nat Med , vol.11 , pp. 780-785
    • Liu, B.1    Wang, J.2    Chan, K.M.3    Tjia, W.M.4    Deng, W.5    Guan, X.6
  • 11
    • 33646745137 scopus 로고    scopus 로고
    • Lamin A-dependent nuclear defects in human aging
    • PMID: 16645051; DOI: 10.1126/science.1127168
    • Scaffidi P, Misteli T. Lamin A-dependent nuclear defects in human aging. Science 2006; 312:1059-63; PMID: 16645051; DOI: 10.1126/science.1127168.
    • (2006) Science , vol.312 , pp. 1059-1063
    • Scaffidi, P.1    Misteli, T.2
  • 12
    • 0026460896 scopus 로고
    • Telomere length predicts replicative capacity of human fibroblasts
    • PMID: 1438199; DOI: 10.1073/pnas.89.21.10114
    • Allsopp RC, Vaziri H, Patterson C, Goldstein S, Younglai EV, Futcher AB, et al. Telomere length predicts replicative capacity of human fibroblasts. Proc Natl Acad Sci USA 1992; 89:10114-8; PMID: 1438199; DOI: 10.1073/pnas.89.21. 10114.
    • (1992) Proc Natl Acad Sci USA , vol.89 , pp. 10114-10118
    • Allsopp, R.C.1    Vaziri, H.2    Patterson, C.3    Goldstein, S.4    Younglai, E.V.5    Futcher, A.B.6
  • 13
    • 67349126486 scopus 로고    scopus 로고
    • Telomere length in Hutchinson-Gilford progeria syndrome
    • PMID: 19428457; DOI: 10.1016/j.mad.2009.03.001
    • Decker ML, Chavez E, Vulto I, Lansdorp PM. Telomere length in Hutchinson-Gilford progeria syndrome. Mech Ageing Dev 2009; 130:377-83; PMID: 19428457; DOI: 10.1016/j.mad.2009.03.001.
    • (2009) Mech Ageing Dev , vol.130 , pp. 377-383
    • Decker, M.L.1    Chavez, E.2    Vulto, I.3    Lansdorp, P.M.4
  • 14
    • 33746883839 scopus 로고    scopus 로고
    • Expression of disease-causing lamin A mutants impairs the formation of DNA repair foci
    • PMID: 16772334; DOI: 10.1242/jcs.03009
    • Manju K, Muralikrishna B, Parnaik VK. Expression of disease-causing lamin A mutants impairs the formation of DNA repair foci. J Cell Sci 2006; 119:2704-14; PMID: 16772334; DOI: 10.1242/jcs.03009.
    • (2006) J Cell Sci , vol.119 , pp. 2704-2714
    • Manju, K.1    Muralikrishna, B.2    Parnaik, V.K.3
  • 15
    • 74849107200 scopus 로고    scopus 로고
    • Loss of A-type lamins and genomic instability
    • PMID: 19901537; DOI: 10.4161/cc.8.23.10092
    • Gonzalez-Suarez I, Redwood AB, Gonzalo S. Loss of A-type lamins and genomic instability. Cell Cycle 2009; 8:3860-5; PMID: 19901537; DOI: 10.4161/cc.8.23.10092.
    • (2009) Cell Cycle , vol.8 , pp. 3860-3865
    • Gonzalez-Suarez, I.1    Redwood, A.B.2    Gonzalo, S.3
  • 16
    • 69249222566 scopus 로고    scopus 로고
    • Novel roles for A-type lamins in telomere biology and the DNA damage response pathway
    • PMID: 19629036; DOI: 10.1038/emboj.2009.196
    • Gonzalez-Suarez I, Redwood AB, Perkins SM, Vermolen B, Lichtensztejin D, Grotsky DA, et al. Novel roles for A-type lamins in telomere biology and the DNA damage response pathway. EMBO J 2009; 28:2414-27; PMID: 19629036; DOI: 10.1038/emboj.2009.196.
    • (2009) EMBO J , vol.28 , pp. 2414-2427
    • Gonzalez-Suarez, I.1    Redwood, A.B.2    Perkins, S.M.3    Vermolen, B.4    Lichtensztejin, D.5    Grotsky, D.A.6
  • 17
    • 70350088548 scopus 로고    scopus 로고
    • Mechanisms of double-strand break repair in somatic mammalian cells
    • PMID: 19772495; DOI: 10.1042/BJ20090942
    • Hartlerode AJ, Scully R. Mechanisms of double-strand break repair in somatic mammalian cells. Biochem J 2009; 423:157-68; PMID: 19772495; DOI: 10.1042/BJ20090942.
    • (2009) Biochem J , vol.423 , pp. 157-168
    • Hartlerode, A.J.1    Scully, R.2
  • 18
    • 70350504453 scopus 로고    scopus 로고
    • The DNA-damage response in human biology and disease
    • PMID: 19847258; DOI: 10.1038/nature08467
    • Jackson SP, Bartek J. The DNA-damage response in human biology and disease. Nature 2009; 461:1071-8; PMID: 19847258; DOI: 10.1038/nature08467.
    • (2009) Nature , vol.461 , pp. 1071-1078
    • Jackson, S.P.1    Bartek, J.2
  • 19
    • 52049098230 scopus 로고    scopus 로고
    • Comparison of nonhomologous end joining and homologous recombination in human cells
    • Amst PMID: 18675941; DOI: 10.1016/j.dnarep.2008.06.018
    • Mao Z, Bozzella M, Seluanov A, Gorbunova V. Comparison of nonhomologous end joining and homologous recombination in human cells. DNA Repair (Amst) 2008; 7:1765-71; PMID: 18675941; DOI: 10.1016/j.dnarep.2008.06.018.
    • (2008) DNA Repair , vol.7 , pp. 1765-1771
    • Mao, Z.1    Bozzella, M.2    Seluanov, A.3    Gorbunova, V.4
  • 20
    • 79952114962 scopus 로고    scopus 로고
    • ATM-independent, high-fidelity nonhomologous end joining predominates in human embryonic stem cells
    • Albany NY
    • Adams BR, Hawkins AJ, Povirk LF, Valerie K. ATM-independent, high-fidelity nonhomologous end joining predominates in human embryonic stem cells. Aging (Albany NY); 2:582-96.
    • Aging , vol.2 , pp. 582-596
    • Adams, B.R.1    Hawkins, A.J.2    Povirk, L.F.3    Valerie, K.4
  • 21
    • 2642570858 scopus 로고    scopus 로고
    • Mechanisms of DNA double strand break repair and chromosome aberration formation
    • PMID: 15162010; DOI: 10.1159/000077461
    • Iliakis G, Wang H, Perrault AR, Boecker W, Rosidi B, Windhofer F, et al. Mechanisms of DNA double strand break repair and chromosome aberration formation. Cytogenet Genome Res 2004; 104:14-20; PMID: 15162010; DOI: 10.1159/000077461.
    • (2004) Cytogenet Genome Res , vol.104 , pp. 14-20
    • Iliakis, G.1    Wang, H.2    Perrault, A.R.3    Boecker, W.4    Rosidi, B.5    Windhofer, F.6
  • 22
    • 0034714199 scopus 로고    scopus 로고
    • Interactions of the DNA ligase IV-XRCC4 complex with DNA ends and the DNA-dependent protein kinase
    • PMID: 10854421; DOI: 10.1074/jbc.M000491200
    • Chen L, Trujillo K, Sung P, Tomkinson AE. Interactions of the DNA ligase IV-XRCC4 complex with DNA ends and the DNA-dependent protein kinase. J Biol Chem 2000; 275:26196-205; PMID: 10854421; DOI: 10.1074/jbc.M000491200.
    • (2000) J Biol Chem , vol.275 , pp. 26196-26205
    • Chen, L.1    Trujillo, K.2    Sung, P.3    Tomkinson, A.E.4
  • 23
    • 0035870583 scopus 로고    scopus 로고
    • Genetic evidence for the involvement of DNA ligase IV in the DNA-PK-dependent pathway of non-homologous end joining in mammalian cells
    • PMID: 11292837; DOI: 10.1093/nar/29.8.1653
    • Wang H, Zeng ZC, Perrault AR, Cheng X, Qin W, Iliakis G. Genetic evidence for the involvement of DNA ligase IV in the DNA-PK-dependent pathway of non-homologous end joining in mammalian cells. Nucleic Acids Res 2001; 29:1653-60; PMID: 11292837; DOI: 10.1093/nar/29.8.1653.
    • (2001) Nucleic Acids Res , vol.29 , pp. 1653-1660
    • Wang, H.1    Zeng, Z.C.2    Perrault, A.R.3    Cheng, X.4    Qin, W.5    Iliakis, G.6
  • 24
    • 66049150672 scopus 로고    scopus 로고
    • SIRT6 stabilizes DNA-dependent protein kinase at chromatin for DNA double-strand break repair
    • Albany NY PMID: 20157594
    • McCord RA, Michishita E, Hong T, Berber E, Boxer LD, Kusumoto R, et al. SIRT6 stabilizes DNA-dependent protein kinase at chromatin for DNA double-strand break repair. Aging (Albany NY) 2009; 1:109-21; PMID: 20157594.
    • (2009) Aging , vol.1 , pp. 109-121
    • McCord, R.A.1    Michishita, E.2    Hong, T.3    Berber, E.4    Boxer, L.D.5    Kusumoto, R.6
  • 25
    • 69249217081 scopus 로고    scopus 로고
    • Sirtuins at the breaking point: SIRT6 in DNA repair
    • Albany NY PMID: 20157593
    • Lombard DB. Sirtuins at the breaking point: SIRT6 in DNA repair. Aging (Albany NY) 2009; 1:12-6; PMID: 20157593.
    • (2009) Aging , vol.1 , pp. 12-16
    • Lombard, D.B.1
  • 26
    • 0030926490 scopus 로고    scopus 로고
    • The scid defect results in much slower repair of DNA double-strand breaks but not high levels of residual breaks
    • PMID: 9146698; DOI: 10.2307/3579619
    • Nevaldine B, Longo JA, Hahn PJ. The scid defect results in much slower repair of DNA double-strand breaks but not high levels of residual breaks. Radiat Res 1997; 147:535-40; PMID: 9146698; DOI: 10.2307/3579619.
    • (1997) Radiat Res , vol.147 , pp. 535-540
    • Nevaldine, B.1    Longo, J.A.2    Hahn, P.J.3
  • 27
    • 11244280890 scopus 로고    scopus 로고
    • Involvement of poly(ADP-ribose) polymerase-1 and XRCC1/DNA ligase III in an alternative route for DNA double-strand breaks rejoining
    • PMID: 15498778; DOI: 10.1074/jbc.M404524200
    • Audebert M, Salles B, Calsou P. Involvement of poly(ADP-ribose) polymerase-1 and XRCC1/DNA ligase III in an alternative route for DNA double-strand breaks rejoining. J Biol Chem 2004; 279:55117-26; PMID: 15498778; DOI: 10.1074/jbc.M404524200.
    • (2004) J Biol Chem , vol.279 , pp. 55117-55126
    • Audebert, M.1    Salles, B.2    Calsou, P.3
  • 28
    • 33845657443 scopus 로고    scopus 로고
    • PARP-1 and Ku compete for repair of DNA double strand breaks by distinct NHEJ pathways
    • PMID: 17088286; DOI: 10.1093/nar/gkl840
    • Wang M, Wu W, Wu W, Rosidi B, Zhang L, Wang H, et al. PARP-1 and Ku compete for repair of DNA double strand breaks by distinct NHEJ pathways. Nucleic Acids Res 2006; 34:6170-82; PMID: 17088286; DOI: 10.1093/nar/gkl840.
    • (2006) Nucleic Acids Res , vol.34 , pp. 6170-6182
    • Wang, M.1    Wu, W.2    Wu, W.3    Rosidi, B.4    Zhang, L.5    Wang, H.6
  • 29
    • 0042632901 scopus 로고    scopus 로고
    • Pathways of DNA double-strand break repair during the mammalian cell cycle
    • PMID: 12897142; DOI: 10.1128/ MCB.23.16.5706-15.2003
    • Rothkamm K, Kruger I, Thompson LH, Lobrich M. Pathways of DNA double-strand break repair during the mammalian cell cycle. Mol Cell Biol 2003; 23:5706-15; PMID: 12897142; DOI: 10.1128/ MCB.23.16.5706-15.2003.
    • (2003) Mol Cell Biol , vol.23 , pp. 5706-5715
    • Rothkamm, K.1    Kruger, I.2    Thompson, L.H.3    Lobrich, M.4
  • 30
    • 6944226229 scopus 로고    scopus 로고
    • MRE11/RAD50/NBS1: Complex activities
    • PMID: 15309560; DOI: 10.1007/s00412-004-0306-4
    • Assenmacher N, Hopfner KP. MRE11/RAD50/NBS1: complex activities. Chromosoma 2004; 113:157-66; PMID: 15309560; DOI: 10.1007/s00412-004-0306-4.
    • (2004) Chromosoma , vol.113 , pp. 157-166
    • Assenmacher, N.1    Hopfner, K.P.2
  • 31
    • 36549060102 scopus 로고    scopus 로고
    • Human CtIP promotes DNA end resection
    • PMID: 17965729; DOI: 10.1038/nature06337
    • Sartori AA, Lukas C, Coates J, Mistrik M, Fu S, Bartek J, et al. Human CtIP promotes DNA end resection. Nature 2007; 450:509-14; PMID: 17965729; DOI: 10.1038/nature06337.
    • (2007) Nature , vol.450 , pp. 509-514
    • Sartori, A.A.1    Lukas, C.2    Coates, J.3    Mistrik, M.4    Fu, S.5    Bartek, J.6
  • 32
    • 67349246802 scopus 로고    scopus 로고
    • CtIP-BRCA1 modulates the choice of DNA double-strand-break repair pathway throughout the cell cycle
    • PMID: 19357644; DOI: 10.1038/nature07955
    • Yun MH, Hiom K. CtIP-BRCA1 modulates the choice of DNA double-strand-break repair pathway throughout the cell cycle. Nature 2009; 459:460-3; PMID: 19357644; DOI: 10.1038/nature07955.
    • (2009) Nature , vol.459 , pp. 460-463
    • Yun, M.H.1    Hiom, K.2
  • 33
    • 43149118369 scopus 로고    scopus 로고
    • Cell cycle-dependent complex formation of BRCA1.CtIP.MRN is important for DNA double-strand break repair
    • PMID: 18171670; DOI: 10.1074/jbc.M710245200
    • Chen L, Nievera CJ, Lee AY, Wu X. Cell cycle-dependent complex formation of BRCA1.CtIP.MRN is important for DNA double-strand break repair. J Biol Chem 2008; 283:7713-20; PMID: 18171670; DOI: 10.1074/jbc.M710245200.
    • (2008) J Biol Chem , vol.283 , pp. 7713-7720
    • Chen, L.1    Nievera, C.J.2    Lee, A.Y.3    Wu, X.4
  • 34
    • 33744947315 scopus 로고    scopus 로고
    • BRCA1 promotes induction of ssDNA by ionizing radiation
    • PMID: 16707442; DOI: 10.1158/0008-5472.CAN-05-3209
    • Schlegel BP, Jodelka FM, Nunez R. BRCA1 promotes induction of ssDNA by ionizing radiation. Cancer Res 2006; 66:5181-9; PMID: 16707442; DOI: 10.1158/0008-5472.CAN-05-3209.
    • (2006) Cancer Res , vol.66 , pp. 5181-5189
    • Schlegel, B.P.1    Jodelka, F.M.2    Nunez, R.3
  • 35
    • 2442707746 scopus 로고    scopus 로고
    • 53BP1 links DNA damage-response pathways to immunoglobulin heavy chain class-switch recombination
    • PMID: 15077110; DOI: 10.1038/ni1067
    • Manis JP, Morales JC, Xia Z, Kutok JL, Alt FW, Carpenter PB. 53BP1 links DNA damage-response pathways to immunoglobulin heavy chain class-switch recombination. Nat Immunol 2004; 5:481-7; PMID: 15077110; DOI: 10.1038/ni1067.
    • (2004) Nat Immunol , vol.5 , pp. 481-487
    • Manis, J.P.1    Morales, J.C.2    Xia, Z.3    Kutok, J.L.4    Alt, F.W.5    Carpenter, P.B.6
  • 36
    • 2542463148 scopus 로고    scopus 로고
    • 53BP1 is required for class switch recombination
    • PMID: 15159415; DOI: 10.1083/jcb.200403021
    • Ward IM, Reina-San-Martin B, Olaru A, Minn K, Tamada K, Lau JS, et al. 53BP1 is required for class switch recombination. J Cell Biol 2004; 165:459-64; PMID: 15159415; DOI: 10.1083/jcb.200403021.
    • (2004) J Cell Biol , vol.165 , pp. 459-464
    • Ward, I.M.1    Reina-San-Martin, B.2    Olaru, A.3    Minn, K.4    Tamada, K.5    Lau, J.S.6
  • 37
    • 57049124828 scopus 로고    scopus 로고
    • 53BP1 facilitates longrange DNA end-joining during V(D)J recombination
    • PMID: 18931658; DOI: 10.1038/nature07476
    • Difilippantonio S, Gapud E, Wong N, Huang CY, Mahowald G, Chen HT, et al. 53BP1 facilitates longrange DNA end-joining during V(D)J recombination. Nature 2008; 456:529-33; PMID: 18931658; DOI: 10.1038/nature07476.
    • (2008) Nature , vol.456 , pp. 529-533
    • Difilippantonio, S.1    Gapud, E.2    Wong, N.3    Huang, C.Y.4    Mahowald, G.5    Chen, H.T.6
  • 38
    • 57049132043 scopus 로고    scopus 로고
    • 53BP1 promotes non-homologous end joining of telomeres by increasing chromatin mobility
    • PMID: 18931659; DOI: 10.1038/nature07433
    • Dimitrova N, Chen YC, Spector DL, de Lange T. 53BP1 promotes non-homologous end joining of telomeres by increasing chromatin mobility. Nature 2008; 456:524-8; PMID: 18931659; DOI: 10.1038/nature07433.
    • (2008) Nature , vol.456 , pp. 524-528
    • Dimitrova, N.1    Chen, Y.C.2    Spector, D.L.3    De Lange, T.4
  • 39
    • 77951057068 scopus 로고    scopus 로고
    • 53BP1 regulates DNA resection and the choice between classical and alternative end joining during class switch recombination
    • PMID: 20368578; DOI: 10.1084/jem.20100244
    • Bothmer A, Robbiani DF, Feldhahn N, Gazumyan A, Nussenzweig A, Nussenzweig MC. 53BP1 regulates DNA resection and the choice between classical and alternative end joining during class switch recombination. J Exp Med 2010; 207:855-65; PMID: 20368578; DOI: 10.1084/jem.20100244.
    • (2010) J Exp Med , vol.207 , pp. 855-865
    • Bothmer, A.1    Robbiani, D.F.2    Feldhahn, N.3    Gazumyan, A.4    Nussenzweig, A.5    Nussenzweig, M.C.6
  • 40
    • 77950958141 scopus 로고    scopus 로고
    • 53BP1 inhibits homologous recombination in Brca1-deficient cells by blocking resection of DNA breaks
    • PMID: 20362325; DOI: 10.1016/j.cell.2010.03.012
    • Bunting SF, Callen E, Wong N, Chen HT, Polato F, Gunn A, et al. 53BP1 inhibits homologous recombination in Brca1-deficient cells by blocking resection of DNA breaks. Cell 2010; 141:243-54; PMID: 20362325; DOI: 10.1016/j.cell.2010. 03.012.
    • (2010) Cell , vol.141 , pp. 243-254
    • Bunting, S.F.1    Callen, E.2    Wong, N.3    Chen, H.T.4    Polato, F.5    Gunn, A.6
  • 41
    • 0032861343 scopus 로고    scopus 로고
    • Megabase chromatin domains involved in DNA double- Strand breaks in vivo
    • PMID: 10477747; DOI: 10.1083/jcb.146.5.905
    • Rogakou EP, Boon C, Redon C, Bonner WM. Megabase chromatin domains involved in DNA double- strand breaks in vivo. J Cell Biol 1999; 146:905-16; PMID: 10477747; DOI: 10.1083/jcb.146.5.905.
    • (1999) J Cell Biol , vol.146 , pp. 905-916
    • Rogakou, E.P.1    Boon, C.2    Redon, C.3    Bonner, W.M.4
  • 42
    • 0034739853 scopus 로고    scopus 로고
    • p53 binding protein 1 (53BP1) is an early participant in the cellular response to DNA double-strand breaks
    • PMID: 11134068; DOI: 10.1083/jcb.151.7.1381
    • Schultz LB, Chehab NH, Malikzay A, Halazonetis TD. p53 binding protein 1 (53BP1) is an early participant in the cellular response to DNA double-strand breaks. J Cell Biol 2000; 151:1381-90; PMID: 11134068; DOI: 10.1083/jcb.151.7. 1381.
    • (2000) J Cell Biol , vol.151 , pp. 1381-1390
    • Schultz, L.B.1    Chehab, N.H.2    Malikzay, A.3    Halazonetis, T.D.4
  • 43
    • 0025270234 scopus 로고
    • Heterogeneity in radiation-induced DNA damage and repair in tumor and normal cells measured using the "comet" assay
    • PMID: 2320728; DOI: 10.2307/3577587
    • Olive PL, Banath JP, Durand RE. Heterogeneity in radiation-induced DNA damage and repair in tumor and normal cells measured using the "comet" assay. Radiat Res 1990; 122:86-94; PMID: 2320728; DOI: 10.2307/3577587.
    • (1990) Radiat Res , vol.122 , pp. 86-94
    • Olive, P.L.1    Banath, J.P.2    Durand, R.E.3
  • 44
    • 0035136283 scopus 로고    scopus 로고
    • Nonhomologous end-joining of ionizing radiation- Induced DNA double-stranded breaks in human tumor cells deficient in BRCA1 or BRCA2
    • PMID: 11196174
    • Wang H, Zeng ZC, Bui TA, DiBiase SJ, Qin W, Xia F, et al. Nonhomologous end-joining of ionizing radiation- induced DNA double-stranded breaks in human tumor cells deficient in BRCA1 or BRCA2. Cancer Res 2001; 61:270-7; PMID: 11196174.
    • (2001) Cancer Res , vol.61 , pp. 270-277
    • Wang, H.1    Zeng, Z.C.2    Bui, T.A.3    DiBiase, S.J.4    Qin, W.5    Xia, F.6
  • 45
    • 77953291328 scopus 로고    scopus 로고
    • 53BP1 loss rescues BRCA1 deficiency and is associated with triple-negative and BRCA-mutated breast cancers
    • PMID: 20453858; DOI: 10.1038/ nsmb.1831
    • Bouwman P, Aly A, Escandell JM, Pieterse M, Bartkova J, van der Gulden H, et al. 53BP1 loss rescues BRCA1 deficiency and is associated with triple-negative and BRCA-mutated breast cancers. Nat Struct Mol Biol 2010; 17:688-95; PMID: 20453858; DOI: 10.1038/ nsmb.1831.
    • (2010) Nat Struct Mol Biol , vol.17 , pp. 688-695
    • Bouwman, P.1    Aly, A.2    Escandell, J.M.3    Pieterse, M.4    Bartkova, J.5    Van Der Gulden, H.6
  • 46
    • 34347388428 scopus 로고    scopus 로고
    • BLM helicase-dependent and -independent roles of 53BP1 during replication stress-mediated homologous recombination
    • PMID: 17591918; DOI: 10.1083/jcb.200610051
    • Tripathi V, Nagarjuna T, Sengupta S. BLM helicase-dependent and -independent roles of 53BP1 during replication stress-mediated homologous recombination. J Cell Biol 2007; 178:9-14; PMID: 17591918; DOI: 10.1083/jcb.200610051.
    • (2007) J Cell Biol , vol.178 , pp. 9-14
    • Tripathi, V.1    Nagarjuna, T.2    Sengupta, S.3
  • 47
    • 27144503470 scopus 로고    scopus 로고
    • MDC1 interacts with Rad51 and facilitates homologous recombination
    • PMID: 16186822; DOI: 10.1038/nsmb991
    • Zhang J, Ma Z, Treszezamsky A, Powell SN. MDC1 interacts with Rad51 and facilitates homologous recombination. Nat Struct Mol Biol 2005; 12:902-9; PMID: 16186822; DOI: 10.1038/nsmb991.
    • (2005) Nat Struct Mol Biol , vol.12 , pp. 902-909
    • Zhang, J.1    Ma, Z.2    Treszezamsky, A.3    Powell, S.N.4
  • 48
    • 77953932126 scopus 로고    scopus 로고
    • The role of RPA2 phosphorylation in homologous recombination in response to replication arrest
    • PMID: 20130019; DOI: 10.1093/carcin/bgq035
    • Shi W, Feng Z, Zhang J, Gonzalez-Suarez I, Vanderwaal RP, Wu X, et al. The role of RPA2 phosphorylation in homologous recombination in response to replication arrest. Carcinogenesis 2010; 31:994-1002; PMID: 20130019; DOI: 10.1093/carcin/bgq035.
    • (2010) Carcinogenesis , vol.31 , pp. 994-1002
    • Shi, W.1    Feng, Z.2    Zhang, J.3    Gonzalez-Suarez, I.4    Vanderwaal, R.P.5    Wu, X.6
  • 49
    • 0030915139 scopus 로고    scopus 로고
    • Inactivation of p53 results in high rates of homologous recombination
    • PMID: 9150391; DOI: 10.1038/sj.onc.1201143
    • Mekeel KL, Tang W, Kachnic LA, Luo CM, DeFrank JS, Powell SN. Inactivation of p53 results in high rates of homologous recombination. Oncogene 1997; 14:1847-57; PMID: 9150391; DOI: 10.1038/sj.onc.1201143.
    • (1997) Oncogene , vol.14 , pp. 1847-1857
    • Mekeel, K.L.1    Tang, W.2    Kachnic, L.A.3    Luo, C.M.4    DeFrank, J.S.5    Powell, S.N.6
  • 50
    • 34047112221 scopus 로고    scopus 로고
    • Repression of RAD51 gene expression by E2F4/p130 complexes in hypoxia
    • PMID: 17001309; DOI: 10.1038/sj.onc.1210001
    • Bindra RS, Glazer PM. Repression of RAD51 gene expression by E2F4/p130 complexes in hypoxia. Oncogene 2007; 26:2048-57; PMID: 17001309; DOI: 10.1038/sj.onc.1210001.
    • (2007) Oncogene , vol.26 , pp. 2048-2057
    • Bindra, R.S.1    Glazer, P.M.2
  • 51
    • 76649094290 scopus 로고    scopus 로고
    • Inhibition of poly(ADP-ribose) polymerase downregulates BRCA1 and RAD51 in a pathway mediated by E2F4 and p130
    • PMID: 20133863; DOI: 10.1073/pnas.0904783107
    • Hegan DC, Lu Y, Stachelek GC, Crosby ME, Bindra RS, Glazer PM. Inhibition of poly(ADP-ribose) polymerase downregulates BRCA1 and RAD51 in a pathway mediated by E2F4 and p130. Proc Natl Acad Sci USA 2010; 107:2201-6; PMID: 20133863; DOI: 10.1073/pnas.0904783107.
    • (2010) Proc Natl Acad Sci USA , vol.107 , pp. 2201-2206
    • Hegan, D.C.1    Lu, Y.2    Stachelek, G.C.3    Crosby, M.E.4    Bindra, R.S.5    Glazer, P.M.6
  • 52
    • 3042829496 scopus 로고    scopus 로고
    • A-type lamins regulate retinoblastoma protein function by promoting subnuclear localization and preventing proteasomal degradation
    • PMID: 15210943; DOI: 10.1073/pnas.0403250101
    • Johnson BR, Nitta RT, Frock RL, Mounkes L, Barbie DA, Stewart CL, et al. A-type lamins regulate retinoblastoma protein function by promoting subnuclear localization and preventing proteasomal degradation. Proc Natl Acad Sci USA 2004; 101:9677-82; PMID: 15210943; DOI: 10.1073/pnas.0403250101.
    • (2004) Proc Natl Acad Sci USA , vol.101 , pp. 9677-9682
    • Johnson, B.R.1    Nitta, R.T.2    Frock, R.L.3    Mounkes, L.4    Barbie, D.A.5    Stewart, C.L.6
  • 53
    • 0036261707 scopus 로고    scopus 로고
    • Sensing and repairing DNA double-strand breaks
    • PMID: 12016139; DOI: 10.1093/carcin/23.5.687.
    • Jackson SP. Sensing and repairing DNA double-strand breaks. Carcinogenesis 2002; 23:687-96; PMID: 12016139; DOI: 10.1093/carcin/23.5.687.
    • (2002) Carcinogenesis , vol.23 , pp. 687-696
    • Jackson, S.P.1
  • 54
    • 0035289717 scopus 로고    scopus 로고
    • Chromosomal stability and the DNA double-stranded break connection
    • PMID: 11256071; DOI: 10.1038/35056049
    • van Gent DC, Hoeijmakers JH, Kanaar R. Chromosomal stability and the DNA double-stranded break connection. Nat Rev Genet 2001; 2:196-206; PMID: 11256071; DOI: 10.1038/35056049.
    • (2001) Nat Rev Genet , vol.2 , pp. 196-206
    • Van Gent, D.C.1    Hoeijmakers, J.H.2    Kanaar, R.3
  • 55
    • 77951976271 scopus 로고    scopus 로고
    • Telomere-dependent and telomere-independent origins of endogenous DNA damage in tumor cells
    • Albany NY PMID: 20157510
    • Nakamura AJ, Redon CE, Bonner WM, Sedelnikova OA. Telomere-dependent and telomere-independent origins of endogenous DNA damage in tumor cells. Aging (Albany NY) 2009; 1:212-8; PMID: 20157510.
    • (2009) Aging , vol.1 , pp. 212-218
    • Nakamura, A.J.1    Redon, C.E.2    Bonner, W.M.3    Sedelnikova, O.A.4
  • 56
    • 79957974187 scopus 로고    scopus 로고
    • Homologous recombination repair is essential for repair of vosaroxin-induced DNA double-strand breaks
    • Hawtin RE, Stockett DE, Wong OK, Lundin C, Helleday T, Fox JA. Homologous recombination repair is essential for repair of vosaroxin-induced DNA double-strand breaks. Oncotarget 1:606-19.
    • Oncotarget , vol.1 , pp. 606-619
    • Hawtin, R.E.1    Stockett, D.E.2    Wong, O.K.3    Lundin, C.4    Helleday, T.5    Fox, J.A.6
  • 57
    • 77951977367 scopus 로고    scopus 로고
    • Endogenous DNA breaks: GammaH2AX and the role of telomeres
    • Albany NY
    • Olive PL. Endogenous DNA breaks: gammaH2AX and the role of telomeres. Aging (Albany NY) 2009; 1:154-6; PMID: 20157507.
    • (2009) Aging , vol.1
    • Olive, P.L.1
  • 58
    • 55549134278 scopus 로고    scopus 로고
    • Tethering by lamin A stabilizes and targets the ING1 tumour suppressor
    • PMID: 18836436; DOI: 10.1038/ncb1792
    • Han X, Feng X, Rattner JB, Smith H, Bose P, Suzuki K, et al. Tethering by lamin A stabilizes and targets the ING1 tumour suppressor. Nat Cell Biol 2008; 10:1333-40; PMID: 18836436; DOI: 10.1038/ncb1792.
    • (2008) Nat Cell Biol , vol.10 , pp. 1333-1340
    • Han, X.1    Feng, X.2    Rattner, J.B.3    Smith, H.4    Bose, P.5    Suzuki, K.6
  • 59
    • 77955419733 scopus 로고    scopus 로고
    • The function of classical and alternative non-homologous end-joining pathways in the fusion of dysfunctional telomeres
    • Rai R, Zheng H, He H, Luo Y, Multani A, Carpenter PB, Chang S. The function of classical and alternative non-homologous end-joining pathways in the fusion of dysfunctional telomeres. EMBO J 2010.
    • (2010) EMBO J
    • Rai, R.1    Zheng, H.2    He, H.3    Luo, Y.4    Multani, A.5    Carpenter, P.B.6    Chang, S.7
  • 60
    • 38949190562 scopus 로고    scopus 로고
    • Involvement of xeroderma pigmentosum group A (XPA) in progeria arising from defective maturation of prelamin A
    • PMID: 17848622; DOI: 10.1096/fj.07-8598com
    • Liu Y, Wang Y, Rusinol AE, Sinensky MS, Liu J, Shell SM, et al. Involvement of xeroderma pigmentosum group A (XPA) in progeria arising from defective maturation of prelamin A. FASEB J 2008; 22:603-11; PMID: 17848622; DOI: 10.1096/fj.07-8598com.
    • (2008) FASEB J , vol.22 , pp. 603-611
    • Liu, Y.1    Wang, Y.2    Rusinol, A.E.3    Sinensky, M.S.4    Liu, J.5    Shell, S.M.6
  • 61
    • 0036578920 scopus 로고    scopus 로고
    • Defective prelamin A processing and muscular and adipocyte alterations in Zmpste24 metalloproteinase-deficient mice
    • PMID: 11923874
    • Pendás AM, Zhou Z, Cadinanos J, Freije JM, Wang J, Hultenby K, et al. Defective prelamin A processing and muscular and adipocyte alterations in Zmpste24 metalloproteinase-deficient mice. Nat Genet 2002; 31:94-9; PMID: 11923874.
    • (2002) Nat Genet , vol.31 , pp. 94-99
    • Pendás, A.M.1    Zhou, Z.2    Cadinanos, J.3    Freije, J.M.4    Wang, J.5    Hultenby, K.6
  • 62
    • 42149158389 scopus 로고    scopus 로고
    • Lamin A/C, laminopathies and premature ageing
    • PMID: 18366013
    • Liu B, Zhou Z. Lamin A/C, laminopathies and premature ageing. Histol Histopathol 2008; 23:747-63; PMID: 18366013.
    • (2008) Histol Histopathol , vol.23 , pp. 747-763
    • Liu, B.1    Zhou, Z.2
  • 63
    • 69949144385 scopus 로고    scopus 로고
    • Genomic instability and DNA damage responses in progeria arising from defective maturation of prelamin A
    • Albany NY PMID: 19851476
    • Musich PR, Zou Y. Genomic instability and DNA damage responses in progeria arising from defective maturation of prelamin A. Aging (Albany NY) 2009; 1:28-37; PMID: 19851476.
    • (2009) Aging , vol.1 , pp. 28-37
    • Musich, P.R.1    Zou, Y.2
  • 64
    • 0033615969 scopus 로고    scopus 로고
    • Loss of A-type lamin expression compromises nuclear envelope integrity leading to muscular dystrophy
    • PMID: 10579712; DOI: 10.1083/ jcb.147.5.913
    • Sullivan T, Escalante-Alcalde D, Bhatt H, Anver M, Bhat N, Nagashima K, et al. Loss of A-type lamin expression compromises nuclear envelope integrity leading to muscular dystrophy. J Cell Biol 1999; 147:913-20; PMID: 10579712; DOI: 10.1083/ jcb.147.5.913.
    • (1999) J Cell Biol , vol.147 , pp. 913-920
    • Sullivan, T.1    Escalante-Alcalde, D.2    Bhatt, H.3    Anver, M.4    Bhat, N.5    Nagashima, K.6
  • 65
    • 27644543144 scopus 로고    scopus 로고
    • The role of the BRCA1 tumor suppressor in DNA double-strand break repair
    • PMID: 16254187; DOI: 10.1158/1541-7786.MCR-05-0192
    • Zhang J, Powell SN. The role of the BRCA1 tumor suppressor in DNA double-strand break repair. Mol Cancer Res 2005; 3:531-9; PMID: 16254187; DOI: 10.1158/1541-7786.MCR-05-0192.
    • (2005) Mol Cancer Res , vol.3 , pp. 531-539
    • Zhang, J.1    Powell, S.N.2
  • 66
    • 0344375083 scopus 로고    scopus 로고
    • Lentivirus-delivered stable gene silencing by RNAi in primary cells
    • PMID: 12649500; DOI: 10.1261/rna.2192803
    • Stewart SA, Dykxhoorn DM, Palliser D, Mizuno H, Yu EY, An DS, et al. Lentivirus-delivered stable gene silencing by RNAi in primary cells. RNA 2003; 9:493-501; PMID: 12649500; DOI: 10.1261/rna.2192803.
    • (2003) RNA , vol.9 , pp. 493-501
    • Stewart, S.A.1    Dykxhoorn, D.M.2    Palliser, D.3    Mizuno, H.4    Yu, E.Y.5    An, D.S.6
  • 67
    • 0025305451 scopus 로고
    • Detection of etoposide resistance by measuring DNA damage in individual Chinese hamster cells
    • PMID: 2325148; DOI: 10.1093/jnci/82.9.779
    • Olive PL, Banath JP, Durand RE. Detection of etoposide resistance by measuring DNA damage in individual Chinese hamster cells. J Natl Cancer Inst 1990; 82:779-83; PMID: 2325148; DOI: 10.1093/jnci/82.9.779.
    • (1990) J Natl Cancer Inst , vol.82 , pp. 779-783
    • Olive, P.L.1    Banath, J.P.2    Durand, R.E.3
  • 68
    • 0034280093 scopus 로고    scopus 로고
    • Mammalian Ku86 protein prevents telomeric fusions independently of the length of TTAGGG repeats and the G-strand overhang
    • PMID: 11256607; DOI: 10.1093/emboreports/ kvd051
    • Samper E, Goytisolo FA, Slijepcevic P, van Buul PP, Blasco MA. Mammalian Ku86 protein prevents telomeric fusions independently of the length of TTAGGG repeats and the G-strand overhang. EMBO Rep 2000; 1:244-52; PMID: 11256607; DOI: 10.1093/emboreports/ kvd051.
    • (2000) EMBO Rep , vol.1 , pp. 244-252
    • Samper, E.1    Goytisolo, F.A.2    Slijepcevic, P.3    Van Buul, P.P.4    Blasco, M.A.5
  • 69
    • 34548313955 scopus 로고    scopus 로고
    • Clonogenic assay of cells in vitro
    • PMID: 17406473; DOI: 10.1038/nprot.2006.339
    • Franken NA, Rodermond HM, Stap J, Haveman J, van Bree C. Clonogenic assay of cells in vitro. Nat Protoc 2006; 1:2315-9; PMID: 17406473; DOI: 10.1038/nprot.2006.339.
    • (2006) Nat Protoc , vol.1 , pp. 2315-2319
    • Franken, N.A.1    Rodermond, H.M.2    Stap, J.3    Haveman, J.4    Van Bree, C.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.