Neuropathology of Cockayne syndrome: Evidence for impaired development, premature aging, and neurodegeneration

Mechanisms of Ageing and Development

Volumn 130, Issue 9, 2009, Pages 619-636

  Weidenheim, Karen M ^a   Dickson, Dennis W ^a,b   Rapin, Isabelle ^a,c  

^a ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

^b MAYO CLINIC   (United States)

^c New York State Office of Mental Retardation and Developmental Disabilities   (United States)

Author keywords

Cachexia; Cell death; Cerebro oculo facial skeletal (COFS) syndrome; Cockayne syndrome (CS); Demyelinating neuropathy; DNA repair; Growth failure; Leukodystrophy; Neurodegeneration; Premature accelerated aging; Transcription; Xeroderma pigmentosum Cockayne (XP CS) complex

Indexed keywords

CELL NUCLEUS DNA; EXCISION REPAIR CROSS COMPLEMENTING PROTEIN 6; EXCISION REPAIR CROSS COMPLEMENTING PROTEIN 8; MITOCHONDRIAL DNA; MYELIN; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG;

ADOLESCENT; ADULT; APOPTOSIS; ARTICLE; ASTROCYTE; BASAL GANGLION; BIOCHEMISTRY; BRAIN ATHEROSCLEROSIS; CACHEXIA; CASE REPORT; CELL DAMAGE; CELL PROLIFERATION; CEREBELLUM; CHILD; COCKAYNE SYNDROME; COFS SYNDROME; DEMYELINATION; DENDRITE; DEVELOPMENTAL DISORDER; DNA DAMAGE; DNA REPAIR; DNA REPLICATION; DNA TRANSCRIPTION; DWARFISM; FEMALE; GENE MUTATION; GENE SILENCING; GENETIC TRANSCRIPTION; GROWTH DISORDER; HUMAN; MALE; MICROCEPHALY; MOLECULAR GENETICS; MULTINUCLEAR CELL; NERVE CELL; NERVE CELL NECROSIS; NERVE DEGENERATION; NERVE FIBER; NEUROPATHOLOGY; OLIGODENDROGLIA; PATHOPHYSIOLOGY; PERIPHERAL NEUROPATHY; PREMATURE AGING; PRESCHOOL CHILD; PRIORITY JOURNAL; PURKINJE CELL; SCHWANN CELL; SENSORY RECEPTOR; STROKE; VASCULAR DISEASE; XERODERMA PIGMENTOSUM;

ADOLESCENT; ADULT; AGING, PREMATURE; CHILD; COCKAYNE SYNDROME; FATAL OUTCOME; FEMALE; HUMANS; MALE; MYELIN SHEATH; NERVE DEGENERATION; NEURONS; PHYSIOLOGICAL PROCESSES;

EID: 69949098944     PISSN: 00476374     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mad.2009.07.006     Document Type: Article

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