메뉴 건너뛰기




Volumn , Issue , 2012, Pages

Nuclear and mitochondrial DNA repair in selected eukaryotic aging model systems

Author keywords

[No Author keywords available]

Indexed keywords

AGING MECHANISM; AGING MODELS; AGING PROCESS; BASIC MECHANISM; DIFFERENT MECHANISMS; DNA REPAIR; EUKARYOTIC CELLS; EUKARYOTIC ORGANISMS; GENETIC STUDIES; HUMAN AGING; MITOCHONDRIAL DNA; MODEL SYSTEM;

EID: 84867379842     PISSN: 19420900     EISSN: 19420994     Source Type: Journal    
DOI: 10.1155/2012/282438     Document Type: Review
Times cited : (32)

References (136)
  • 1
    • 0027082270 scopus 로고
    • Role of free radicals in aging and disease
    • DOI 10.1111/j.1749-6632.1992.tb27444.x
    • Harman D., Role of free radicals in aging and disease. Annals of the New York Academy of Sciences 1992 673 126 141 2-s2.0-0027082270 10.1111/j.1749-6632. 1992.tb27444.x (Pubitemid 23057567)
    • (1992) Annals of the New York Academy of Sciences , vol.673 , pp. 126-141
    • Harman, D.1
  • 2
    • 84858964912 scopus 로고    scopus 로고
    • Age-dependent increases in the oxidative damage of DNA, RNA, and their metabolites in normal and senescence-accelerated mice analyzed by LC-MS/MS: Urinary 8-oxoguanosine as a novel biomarker of aging
    • Gan W., Nie B., Shi F., Age-dependent increases in the oxidative damage of DNA, RNA, and their metabolites in normal and senescence-accelerated mice analyzed by LC-MS/MS: urinary 8-oxoguanosine as a novel biomarker of aging. Free Radical Biology and Medicine 2012 52 9 1700 1707
    • (2012) Free Radical Biology and Medicine , vol.52 , Issue.9 , pp. 1700-1707
    • Gan, W.1    Nie, B.2    Shi, F.3
  • 3
    • 84864010124 scopus 로고    scopus 로고
    • The oxidative DNA lesions 8, 5 ′ -cyclopurines accumulate with aging in a tissue-specific manner
    • 10.1111/j.1474-9726.2012.00828.x
    • Wang J., Clauson C. L., Robbins P. D., The oxidative DNA lesions 8, 5 ′ -cyclopurines accumulate with aging in a tissue-specific manner. Aging Cell 2012 11 4 714 716 10.1111/j.1474-9726.2012.00828.x
    • (2012) Aging Cell , vol.11 , Issue.4 , pp. 714-716
    • Wang, J.1    Clauson, C.L.2    Robbins, P.D.3
  • 4
    • 26944486677 scopus 로고    scopus 로고
    • Age-related changes in oxidative DNA damage and benzo(a)pyrene diolepoxide-I (BPDE-I)-DNA adduct levels in human stomach
    • DOI 10.1080/15287390500182818
    • Lee B. M., Kwack S. J., Kim H. S., Age-related changes in oxidative DNA damage and benzo(a)pyrene diolepoxide-I (BPDE-I)-DNA adduct levels in human stomach. Journal of Toxicology and Environmental Health A 2005 68 19 1599 1610 2-s2.0-26944486677 10.1080/15287390500182818 (Pubitemid 41783265)
    • (2005) Journal of Toxicology and Environmental Health - Part A , vol.68 , Issue.19 , pp. 1599-1610
    • Byung, M.L.1    Seung, J.K.2    Hyung, S.K.3
  • 7
    • 35348892775 scopus 로고    scopus 로고
    • Photoageing: Mechanism, prevention and therapy
    • DOI 10.1111/j.1365-2133.2007.08108.x
    • Yaar M., Gilchrest B. A., Photoageing: mechanism, prevention and therapy. British Journal of Dermatology 2007 157 5 874 887 2-s2.0-35348892775 10.1111/j.1365-2133.2007.08108.x (Pubitemid 47583483)
    • (2007) British Journal of Dermatology , vol.157 , Issue.5 , pp. 874-887
    • Yaar, M.1    Gilchrest, B.A.2
  • 8
    • 9644269056 scopus 로고    scopus 로고
    • Genotoxicity of environmental tobacco smoke: A review
    • DOI 10.1016/j.mrrev.2004.06.004, PII S1383574204000638
    • Husgafvel-Pursiainen K., Genotoxicity of environmental tobacco smoke: a review. Mutation Research 2004 567 2-3 427 445 2-s2.0-9644269056 10.1016/j.mrrev.2004.06.004 (Pubitemid 39574547)
    • (2004) Mutation Research - Reviews in Mutation Research , vol.567 , Issue.2-3 SPEC. ISSUE , pp. 427-445
    • Husgafvel-Pursiainen, K.1
  • 9
    • 35649020227 scopus 로고    scopus 로고
    • Tobacco smoke causes premature skin aging
    • DOI 10.1016/j.jdermsci.2007.06.015, PII S0923181107003210
    • Morita A., Tobacco smoke causes premature skin aging. Journal of Dermatological Science 2007 48 3 169 175 2-s2.0-35649020227 10.1016/j.jdermsci. 2007.06.015 (Pubitemid 350026284)
    • (2007) Journal of Dermatological Science , vol.48 , Issue.3 , pp. 169-175
    • Morita, A.1
  • 10
    • 0035682050 scopus 로고    scopus 로고
    • DNA double-strand breaks in mouse kidney cells with age
    • DOI 10.1023/A:1013262327193
    • Singh N. P., Ogburn C. E., Wolf N. S., Van Belle G., Martin G. M., DNA double-strand breaks in mouse kidney cells with age. Biogerontology 2001 2 4 261 270 2-s2.0-0035682050 10.1023/A:1013262327193 (Pubitemid 34081094)
    • (2001) Biogerontology , vol.2 , Issue.4 , pp. 261-270
    • Singh, N.P.1    Ogburn, C.E.2    Wolf, N.S.3    Van Belle, G.4    Martin, G.M.5
  • 11
    • 80053128348 scopus 로고    scopus 로고
    • Study of DNA damage via the comet assay and base excision repair activities in rat brain neurons and astrocytes during aging
    • 2-s2.0-79957639404 10.1016/j.mad.2011.04.012
    • Swain U., Subba Rao K., Study of DNA damage via the comet assay and base excision repair activities in rat brain neurons and astrocytes during aging. Mechanisms of Ageing and Development 2011 132 89 374 381 2-s2.0-79957639404 10.1016/j.mad.2011.04.012
    • (2011) Mechanisms of Ageing and Development , vol.132 , Issue.89 , pp. 374-381
    • Swain, U.1    Subba Rao, K.2
  • 12
    • 79952750172 scopus 로고    scopus 로고
    • Multiple DNA damage recognition factors involved in mammalian nucleotide excision repair
    • 2-s2.0-79952750172 10.1134/S0006297911010044
    • Sugasawa K., Multiple DNA damage recognition factors involved in mammalian nucleotide excision repair. Biochemistry 2011 76 1 16 23 2-s2.0-79952750172 10.1134/S0006297911010044
    • (2011) Biochemistry , vol.76 , Issue.1 , pp. 16-23
    • Sugasawa, K.1
  • 13
    • 0034054019 scopus 로고    scopus 로고
    • Nucleotide excision repair and human syndromes
    • de Boer J., Hoeijmakers J. H. J., Nucleotide excision repair and human syndromes. Carcinogenesis 2000 21 3 453 460 2-s2.0-0034054019 (Pubitemid 30137930)
    • (2000) Carcinogenesis , vol.21 , Issue.3 , pp. 453-460
    • De Boer, J.1    Hoeijmakers, J.H.J.2
  • 14
    • 79956205888 scopus 로고    scopus 로고
    • DNA repair deficiency in neurodegeneration
    • 2-s2.0-79956205888 10.1016/j.pneurobio.2011.04.013
    • Jeppesen D. K., Bohr V. A., Stevnsner T., DNA repair deficiency in neurodegeneration. Progress in Neurobiology 2011 94 2 166 200 2-s2.0-79956205888 10.1016/j.pneurobio.2011.04.013
    • (2011) Progress in Neurobiology , vol.94 , Issue.2 , pp. 166-200
    • Jeppesen, D.K.1    Bohr, V.A.2    Stevnsner, T.3
  • 15
    • 77953348161 scopus 로고    scopus 로고
    • Mitochondrial DNA repair and association with agingan update
    • 2-s2.0-77953348161 10.1016/j.exger.2010.01.017
    • Gredilla R., Bohr V. A., Stevnsner T., Mitochondrial DNA repair and association with agingan update. Experimental Gerontology 2010 45 7-8 478 488 2-s2.0-77953348161 10.1016/j.exger.2010.01.017
    • (2010) Experimental Gerontology , vol.45 , Issue.7-8 , pp. 478-488
    • Gredilla, R.1    Bohr, V.A.2    Stevnsner, T.3
  • 16
    • 0034733899 scopus 로고    scopus 로고
    • Base excision repair of DNA in mammalian cells
    • DOI 10.1016/S0014-5793(00)01674-4, PII S0014579300016744
    • Krokan H. E., Nilsen H., Skorpen F., Otterlei M., Slupphaug G., Base excision repair of DNA in mammalian cells. FEBS Letters 2000 476 1-2 73 77 2-s2.0-0034733899 10.1016/S0014-5793(00)01674-4 (Pubitemid 30394654)
    • (2000) FEBS Letters , vol.476 , Issue.1-2 , pp. 73-77
    • Krokan, H.E.1    Nilsen, H.2    Skorpen, F.3    Otterlei, M.4    Slupphaug, G.5
  • 17
    • 0035902108 scopus 로고    scopus 로고
    • Genome maintenance mechanisms for preventing cancer
    • DOI 10.1038/35077232
    • Hoeijmakers J. H. J., Genome maintenance mechanisms for preventing cancer. Nature 2001 411 6835 366 374 2-s2.0-0035902108 10.1038/35077232 (Pubitemid 32467046)
    • (2001) Nature , vol.411 , Issue.6835 , pp. 366-374
    • Hoeijmakers, J.H.J.1
  • 18
    • 84866247628 scopus 로고    scopus 로고
    • DNA damage and base excision repair in mitochondria and their role in aging
    • 257093
    • Gredilla R., DNA damage and base excision repair in mitochondria and their role in aging. Journal of Aging Research 2010 2011 257093
    • (2010) Journal of Aging Research , vol.2011
    • Gredilla, R.1
  • 19
    • 0026775958 scopus 로고
    • Free radical theory of aging
    • 2-s2.0-0026775958 10.1016/0921-8734(92)90030-S
    • Harman D., Free radical theory of aging. Mutation Research 1992 275 36 257 266 2-s2.0-0026775958 10.1016/0921-8734(92)90030-S
    • (1992) Mutation Research , vol.275 , Issue.36 , pp. 257-266
    • Harman, D.1
  • 20
    • 33846243745 scopus 로고    scopus 로고
    • An integrated view of oxidative stress in aging: Basic mechanisms, functional effects, and pathological considerations
    • DOI 10.1152/ajpregu.00327.2006
    • Kregel K. C., Zhang H. J., An integrated view of oxidative stress in aging: basic mechanisms, functional effects, and pathological considerations. American Journal of Physiology 2007 292 1 R18 R36 2-s2.0-33846243745 10.1152/ajpregu.00327.2006 (Pubitemid 46091599)
    • (2007) American Journal of Physiology - Regulatory Integrative and Comparative Physiology , vol.292 , Issue.1
    • Kregel, K.C.1    Zhang, H.J.2
  • 21
    • 0037878634 scopus 로고    scopus 로고
    • Base excision repair activities required for yeast to attain a full chronological life span
    • 2-s2.0-0037878634
    • Maclean M. J., Aamodt R., Harris N., Alseth I., Seeberg E., Bjorås M., Piper P. W., Base excision repair activities required for yeast to attain a full chronological life span. Aging Cell 2003 2 2 93 104 2-s2.0-0037878634
    • (2003) Aging Cell , vol.2 , Issue.2 , pp. 93-104
    • MacLean, M.J.1    Aamodt, R.2    Harris, N.3    Alseth, I.4    Seeberg, E.5    Bjorås, M.6    Piper, P.W.7
  • 22
    • 36549083391 scopus 로고    scopus 로고
    • Declining cellular fitness with age promotes cancer initiation by selecting for adaptive oncogenic mutations
    • DOI 10.1016/j.bbcan.2007.09.001, PII S0304419X07000418
    • Marusyk A., DeGregori J., Declining cellular fitness with age promotes cancer initiation by selecting for adaptive oncogenic mutations. Biochimica et Biophysica Acta 2008 1785 1 1 11 2-s2.0-36549083391 10.1016/j.bbcan.2007.09.001 (Pubitemid 350192081)
    • (2008) Biochimica et Biophysica Acta - Reviews on Cancer , vol.1785 , Issue.1 , pp. 1-11
    • Marusyk, A.1    DeGregori, J.2
  • 23
    • 33847007529 scopus 로고    scopus 로고
    • The mechanics of base excision repair, and its relationship to aging and disease
    • DOI 10.1016/j.dnarep.2006.10.017, PII S1568786406003260, Repair of small base lesions in DNA-from molecular biology to phenotype
    • Wilson D. M. III, Bohr V. A., The mechanics of base excision repair, and its relationship to aging and disease. DNA Repair 2007 6 4 544 559 2-s2.0-33847007529 10.1016/j.dnarep.2006.10.017 (Pubitemid 46357056)
    • (2007) DNA Repair , vol.6 , Issue.4 , pp. 544-559
    • Wilson III, D.M.1    Bohr, V.A.2
  • 24
    • 55049112210 scopus 로고    scopus 로고
    • Human DNA2 is a mitochondrial nuclease/helicase for efficient processing of DNA replication and repair intermediates
    • 2-s2.0-55049112210 10.1016/j.molcel.2008.09.024
    • Zheng L., Zhou M., Guo Z., Lu H., Qian L., Dai H., Qiu J., Yakubovskaya E., Bogenhagen D. F., Demple B., Shen B., Human DNA2 is a mitochondrial nuclease/helicase for efficient processing of DNA replication and repair intermediates. Molecular Cell 2008 32 3 325 336 2-s2.0-55049112210 10.1016/j.molcel.2008.09.024
    • (2008) Molecular Cell , vol.32 , Issue.3 , pp. 325-336
    • Zheng, L.1    Zhou, M.2    Guo, Z.3    Lu, H.4    Qian, L.5    Dai, H.6    Qiu, J.7    Yakubovskaya, E.8    Bogenhagen, D.F.9    Demple, B.10    Shen, B.11
  • 25
    • 55949088844 scopus 로고    scopus 로고
    • DNA2 resolves expanding flap in mitochondrial base excision repair
    • 2-s2.0-55949088844 10.1016/j.molcel.2008.11.007
    • Copeland W. C., Longley M. J., DNA2 resolves expanding flap in mitochondrial base excision repair. Molecular Cell 2008 32 4 457 458 2-s2.0-55949088844 10.1016/j.molcel.2008.11.007
    • (2008) Molecular Cell , vol.32 , Issue.4 , pp. 457-458
    • Copeland, W.C.1    Longley, M.J.2
  • 26
    • 33646187811 scopus 로고    scopus 로고
    • The multifaceted mismatch-repair system
    • 2-s2.0-33646187811 10.1038/nrm1907
    • Jiricny J., The multifaceted mismatch-repair system. Nature Reviews Molecular Cell Biology 2006 7 5 335 346 2-s2.0-33646187811 10.1038/nrm1907
    • (2006) Nature Reviews Molecular Cell Biology , vol.7 , Issue.5 , pp. 335-346
    • Jiricny, J.1
  • 28
    • 50249095733 scopus 로고    scopus 로고
    • An optimized method for measurement of gamma-H2AX in blood mononuclear and cultured cells
    • 2-s2.0-50249095733 10.1038/nprot.2008.93
    • Muslimovic A., Ismail I. H., Gao Y., Hammarsten O., An optimized method for measurement of gamma-H2AX in blood mononuclear and cultured cells. Nature Protocols 2008 3 7 1187 1193 2-s2.0-50249095733 10.1038/nprot.2008.93
    • (2008) Nature Protocols , vol.3 , Issue.7 , pp. 1187-1193
    • Muslimovic, A.1    Ismail, I.H.2    Gao, Y.3    Hammarsten, O.4
  • 30
    • 67650578601 scopus 로고    scopus 로고
    • DNA-PKcs and ATM co-regulate DNA double-strand break repair
    • 2-s2.0-67650578601 10.1016/j.dnarep.2009.05.006
    • Shrivastav M., Miller C. A., De Haro L. P., Durant S. T., Chen B. P. C., Chen D. J., Nickoloff J. A., DNA-PKcs and ATM co-regulate DNA double-strand break repair. DNA Repair 2009 8 8 920 929 2-s2.0-67650578601 10.1016/j.dnarep.2009.05.006
    • (2009) DNA Repair , vol.8 , Issue.8 , pp. 920-929
    • Shrivastav, M.1    Miller, C.A.2    De Haro, L.P.3    Durant, S.T.4    Chen, B.P.C.5    Chen, D.J.6    Nickoloff, J.A.7
  • 31
    • 38049155945 scopus 로고    scopus 로고
    • Regulation of DNA double-strand break repair pathway choice
    • 2-s2.0-38049155945 10.1038/cr.2007.111
    • Shrivastav M., De Haro L. P., Nickoloff J. A., Regulation of DNA double-strand break repair pathway choice. Cell Research 2008 18 1 134 147 2-s2.0-38049155945 10.1038/cr.2007.111
    • (2008) Cell Research , vol.18 , Issue.1 , pp. 134-147
    • Shrivastav, M.1    De Haro, L.P.2    Nickoloff, J.A.3
  • 32
    • 0037423743 scopus 로고    scopus 로고
    • Coordinated assembly of Ku and p460 subunits of the DNA-dependent protein kinase on DNA ends is necessary for XRCC4-ligase IV recruitment
    • DOI 10.1016/S0022-2836(02)01328-1
    • Calsou P., Delteil C., Frit P., Drouet J., Salles B., Coordinated assembly of Ku and p460 subunits of the DNA-dependent protein kinase on DNA ends is necessary for XRCC4-ligase IV recruitment. Journal of Molecular Biology 2003 326 1 93 103 2-s2.0-0037423743 10.1016/S0022-2836(02)01328-1 (Pubitemid 36279360)
    • (2003) Journal of Molecular Biology , vol.326 , Issue.1 , pp. 93-103
    • Calsou, P.1    Delteil, C.2    Frit, P.3    Drouet, J.4    Salles, B.5
  • 33
    • 0033572709 scopus 로고    scopus 로고
    • Geometry of a complex formed by double strand break repair proteins at a single DNA end: Recruitment of DNA-PKcs induces inward translocation of Ku protein
    • Yoo S., Dynan W. S., Geometry of a complex formed by double strand break repair proteins at a single DNA end: recruitment of DNA-PKcs induces inward translocation of Ku protein. Nucleic Acids Research 1999 27 24 4679 4686 2-s2.0-0033572709 (Pubitemid 30006656)
    • (1999) Nucleic Acids Research , vol.27 , Issue.24 , pp. 4679-4686
    • Yoo, S.1    Dynan, W.S.2
  • 34
    • 4043073590 scopus 로고    scopus 로고
    • Autophosphorylation-dependent remodeling of the DNA-dependent protein kinase catalytic subunit regulates ligation of DNA ends
    • DOI 10.1093/nar/gkh761
    • Block W. D., Yu Y., Merkle D., Gifford J. L., Ding Q., Meek K., Lees-Miller S. P., Autophosphorylation-dependent remodeling of the DNA-dependent protein kinase catalytic subunit regulates ligation of DNA ends. Nucleic Acids Research 2004 32 14 4351 4357 2-s2.0-4043073590 10.1093/nar/gkh761 (Pubitemid 39232307)
    • (2004) Nucleic Acids Research , vol.32 , Issue.14 , pp. 4351-4357
    • Block, W.D.1    Yu, Y.2    Merkle, D.3    Gifford, J.L.4    Ding, Q.5    Meek, K.6    Lees-Miller, S.P.7
  • 35
    • 61849118621 scopus 로고    scopus 로고
    • Mechanisms of formation and accumulation of mitochondrial DNA deletions in aging neurons
    • 2-s2.0-61849118621 10.1093/hmg/ddn437
    • Fukui H., Moraes C. T., Mechanisms of formation and accumulation of mitochondrial DNA deletions in aging neurons. Human Molecular Genetics 2009 18 6 1028 1036 2-s2.0-61849118621 10.1093/hmg/ddn437
    • (2009) Human Molecular Genetics , vol.18 , Issue.6 , pp. 1028-1036
    • Fukui, H.1    Moraes, C.T.2
  • 36
    • 33644635644 scopus 로고    scopus 로고
    • DNA polymerase γ in mitochondrial DNA replication and repair
    • 2-s2.0-33644635644 10.1021/cr040463d
    • Graziewicz M. A., Longley M. J., Copeland W. C., DNA polymerase γ in mitochondrial DNA replication and repair. Chemical Reviews 2006 106 2 383 405 2-s2.0-33644635644 10.1021/cr040463d
    • (2006) Chemical Reviews , vol.106 , Issue.2 , pp. 383-405
    • Graziewicz, M.A.1    Longley, M.J.2    Copeland, W.C.3
  • 37
    • 37149039807 scopus 로고    scopus 로고
    • Bleomycin-induced double-strand breaks in mitochondrial DNA of Drosophila cells are repaired
    • DOI 10.1016/j.mrfmmm.2007.07.007, PII S0027510707002886
    • Morel F., Renoux M., Lachaume P., Alziari S., Bleomycin-induced double-strand breaks in mitochondrial DNA of Drosophila cells are repaired. Mutation Research 2008 637 1-2 111 117 2-s2.0-37149039807 10.1016/j.mrfmmm.2007. 07.007 (Pubitemid 350256768)
    • (2008) Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis , vol.637 , Issue.1-2 , pp. 111-117
    • Morel, F.1    Renoux, M.2    Lachaume, P.3    Alziari, S.4
  • 39
    • 77953484497 scopus 로고    scopus 로고
    • DNA repair in mammalian mitochondria: Much more than we thought?
    • 2-s2.0-77953484497 10.1002/em.20576
    • Liu P., Demple B., DNA repair in mammalian mitochondria: much more than we thought? Environmental and Molecular Mutagenesis 2010 51 5 417 426 2-s2.0-77953484497 10.1002/em.20576
    • (2010) Environmental and Molecular Mutagenesis , vol.51 , Issue.5 , pp. 417-426
    • Liu, P.1    Demple, B.2
  • 40
    • 84865214259 scopus 로고    scopus 로고
    • The continuing value of twin studies in the omics era
    • 2-s2.0-84865214259 10.1038/nrg3243
    • van Dongen J., Slagboom P. E., Draisma H. H. M., The continuing value of twin studies in the omics era. Nature Reviews Genetics 2012 13 9 640 653 2-s2.0-84865214259 10.1038/nrg3243
    • (2012) Nature Reviews Genetics , vol.13 , Issue.9 , pp. 640-653
    • Van Dongen, J.1    Slagboom, P.E.2    Draisma, H.H.M.3
  • 41
    • 0027482067 scopus 로고
    • Longevity is moderately heritable in a sample of Danish twins born 1870- 1880
    • McGue M., Vaupel J. W., Holm N., Harvald B., Longevity is moderately heritable in a sample of Danish twins born 18701880. Journals of Gerontology 1993 48 6 B237 B244 2-s2.0-0027482067 (Pubitemid 23333633)
    • (1993) Journals of Gerontology , vol.48 , Issue.6
    • McGue, M.1    Vaupel, J.W.2    Holm, N.3    Harvald, B.4
  • 42
    • 0030062815 scopus 로고    scopus 로고
    • The heritability of human longevity: A population-based study of 2872 Danish twin pairs born 1870-1900
    • DOI 10.1007/s004390050042
    • Herskind A. M., McGue M., Holm N. V., Sorensen T. I. A., Harvald B., Vaupel J. W., The heritability of human longevity: a population-based study of 2872 Danish twin pairs born 18701900. Human Genetics 1996 97 3 319 323 2-s2.0-0030062815 10.1007/s004390050042 (Pubitemid 26057031)
    • (1996) Human Genetics , vol.97 , Issue.3 , pp. 319-323
    • Herskind, A.M.1    McGue, M.2    Holm, N.V.3    Sorensen, T.I.A.4    Harvald, B.5    Vaupel, J.W.6
  • 45
    • 78249280592 scopus 로고    scopus 로고
    • Replication of an association of variation in the FOXO3A gene with human longevity using both case-control and longitudinal data
    • 2-s2.0-78249280592 10.1111/j.1474-9726.2010.00627.x
    • Soerensen M., Dato S., Christensen K., McGue M., Stevnsner T., Bohr V. A., Christiansen L., Replication of an association of variation in the FOXO3A gene with human longevity using both case-control and longitudinal data. Aging Cell 2010 9 6 1010 1017 2-s2.0-78249280592 10.1111/j.1474-9726.2010.00627.x
    • (2010) Aging Cell , vol.9 , Issue.6 , pp. 1010-1017
    • Soerensen, M.1    Dato, S.2    Christensen, K.3    McGue, M.4    Stevnsner, T.5    Bohr, V.A.6    Christiansen, L.7
  • 46
    • 84858322507 scopus 로고    scopus 로고
    • Role of forkhead transcription factors in diabetes-induced oxidative stress
    • 939751 2-s2.0-34548486662 10.1155/2012/939751
    • Ponugoti B., Dong G., Graves D. T., Role of forkhead transcription factors in diabetes-induced oxidative stress. Experimental Diabetes Research 2012 2012 7 939751 2-s2.0-34548486662 10.1155/2012/939751
    • (2012) Experimental Diabetes Research , vol.2012 , pp. 7
    • Ponugoti, B.1    Dong, G.2    Graves, D.T.3
  • 47
    • 0037134040 scopus 로고    scopus 로고
    • DNA repair pathway stimulated by the forkhead transcription factor FOXO3a through the Gadd45 protein
    • DOI 10.1126/science.1068712
    • Tran H., Brunet A., Grenier J. M., Datta S. R., Fornace A. J., DiStefano P. S., Chiang L. W., Greenberg M. E., DNA repair pathway stimulated by the forkhead transcription factor FOXO3A through the Gadd45 protein. Science 2002 296 5567 530 534 2-s2.0-0037134040 10.1126/science.1068712 (Pubitemid 34408672)
    • (2002) Science , vol.296 , Issue.5567 , pp. 530-534
    • Tran, H.1    Brunet, A.2    Grenier, J.M.3    Datta, S.R.4    Fornace Jr., A.J.5    DiStefano, P.S.6    Chiang, L.W.7    Greenberg, M.E.8
  • 49
    • 4344649809 scopus 로고    scopus 로고
    • Is hEXO1 a cancer predisposing gene?
    • Liberti S. E., Rasmussen L. J., Is hEXO1 a cancer predisposing gene? Molecular Cancer Research 2004 2 8 427 432 2-s2.0-4344649809 (Pubitemid 39121505)
    • (2004) Molecular Cancer Research , vol.2 , Issue.8 , pp. 427-432
    • Liberti, S.E.1    Rasmussen, L.J.2
  • 50
    • 0037593470 scopus 로고    scopus 로고
    • The exonucleolytic and endonucleolytic cleavage activities of human exonuclease 1 are stimulated by an interaction with the carboxyl-terminal region of the Werner syndrome protein
    • DOI 10.1074/jbc.M212798200
    • Sharma S., Sommers J. A., Driscoll H. C., Uzdilla L., Wilson T. M., Brosh R. M., The exonucleolytic and endonucleolytic cleavage activities of human exonuclease 1 are stimulated by an interaction with the carboxyl-terminal region of the Werner syndrome protein. Journal of Biological Chemistry 2003 278 26 23487 23496 2-s2.0-0037593470 10.1074/jbc.M212798200 (Pubitemid 36830166)
    • (2003) Journal of Biological Chemistry , vol.278 , Issue.26 , pp. 23487-23496
    • Sharma, S.1    Sommers, J.A.2    Driscoll, H.C.3    Uzdilla, L.4    Wilson, T.M.5    Brosh Jr., R.M.6
  • 51
    • 0034639302 scopus 로고    scopus 로고
    • Polymorphisms at the Werner locus: II., 1074Leu/Phe, 1367Cys/Arg, longevity, and atherosclerosis
    • Castro E., Edland S. D., Lee L., Polymorphisms at the Werner locus: II., 1074Leu/Phe, 1367Cys/Arg, longevity, and atherosclerosis. American Journal of Medical Genetics A 2000 95 4 374 380
    • (2000) American Journal of Medical Genetics A , vol.95 , Issue.4 , pp. 374-380
    • Castro, E.1    Edland, S.D.2    Lee, L.3
  • 53
    • 79959503826 scopus 로고    scopus 로고
    • The International HapMap Project
    • International HapMap Consortium
    • International HapMap Consortium, The International HapMap Project. Nature 2003 426 6968 789 796
    • (2003) Nature , vol.426 , Issue.6968 , pp. 789-796
  • 54
    • 84859853540 scopus 로고    scopus 로고
    • Human longevity and variation in GH/IGF-1/insulin signaling, DNA damage signaling and repair and pro/antioxidant pathway genes: Cross sectional and longitudinal studies
    • Soerensen M., Dato S., Tan Q., Human longevity and variation in GH/IGF-1/insulin signaling, DNA damage signaling and repair and pro/antioxidant pathway genes: cross sectional and longitudinal studies. Experimental Gerontology 2012 47 5 379 387
    • (2012) Experimental Gerontology , vol.47 , Issue.5 , pp. 379-387
    • Soerensen, M.1    Dato, S.2    Tan, Q.3
  • 55
    • 76549104441 scopus 로고    scopus 로고
    • Evolution in health and medicine Sackler colloquium: Genetic variation in human telomerase is associated with telomere length in Ashkenazi centenarians
    • supplement 1
    • Atzmon G., Cho M., Cawthon R. M., Evolution in health and medicine Sackler colloquium: genetic variation in human telomerase is associated with telomere length in Ashkenazi centenarians. Proceedings of the National Academy of Sciences of the United States of America 2010 107 supplement 1 1710 1717
    • (2010) Proceedings of the National Academy of Sciences of the United States of America , vol.107 , pp. 1710-1717
    • Atzmon, G.1    Cho, M.2    Cawthon, R.M.3
  • 57
    • 24944460598 scopus 로고    scopus 로고
    • Shelterin: The protein complex that shapes and safeguards human telomeres
    • DOI 10.1101/gad.1346005
    • de Lange T., Shelterin: the protein complex that shapes and safeguards human telomeres. Genes and Development 2005 19 18 2100 2110 2-s2.0-24944460598 10.1101/gad.1346005 (Pubitemid 41330312)
    • (2005) Genes and Development , vol.19 , Issue.18 , pp. 2100-2110
    • De Lange, T.1
  • 58
    • 0037148271 scopus 로고    scopus 로고
    • Telomerase in the human organism
    • DOI 10.1038/sj/onc/1205083
    • Collins K., Mitchell J. R., Telomerase in the human organism. Oncogene 2002 21 4 564 579 2-s2.0-0037148271 10.1038/sj/onc/1205083 (Pubitemid 34146256)
    • (2002) Oncogene , vol.21 , Issue.4 REV. ISS. 1 , pp. 564-579
    • Collins, K.1    Mitchell, J.R.2
  • 61
    • 84858337182 scopus 로고    scopus 로고
    • Genetic variation in TERT and TERC and human leukocyte telomere length and longevity: A cross-sectional and longitudinal analysis
    • Soerensen M., Thinggaard M., Nygaard M., Genetic variation in TERT and TERC and human leukocyte telomere length and longevity: a cross-sectional and longitudinal analysis. Aging Cell 2012 11 2 223 227
    • (2012) Aging Cell , vol.11 , Issue.2 , pp. 223-227
    • Soerensen, M.1    Thinggaard, M.2    Nygaard, M.3
  • 63
    • 0035019950 scopus 로고    scopus 로고
    • Radiation sensitivity of lymphocytes from healthy individuals and cancer patients as measured by the comet assay
    • DOI 10.1007/s004110000087
    • Müller W. U., Bauch T., Stüben G., Sack H., Streffer C., Radiation sensitivity of lymphocytes from healthy individuals and cancer patients as measured by the comet assay. Radiation and Environmental Biophysics 2001 40 1 83 89 2-s2.0-0035019950 10.1007/s004110000087 (Pubitemid 32411007)
    • (2001) Radiation and Environmental Biophysics , vol.40 , Issue.1 , pp. 83-89
    • Muller, W.-U.1    Bauch, T.2    Stuben, G.3    Sack, H.4    Streffer, C.5
  • 65
    • 56349098659 scopus 로고    scopus 로고
    • Age, sex, and race influence single-strand break repair capacity in a human population
    • 2-s2.0-56349098659 10.1016/j.freeradbiomed.2008.08.031
    • Trzeciak A. R., Barnes J., Ejiogu N., Foster K., Brant L. J., Zonderman A. B., Evans M. K., Age, sex, and race influence single-strand break repair capacity in a human population. Free Radical Biology and Medicine 2008 45 12 1631 1641 2-s2.0-56349098659 10.1016/j.freeradbiomed.2008.08.031
    • (2008) Free Radical Biology and Medicine , vol.45 , Issue.12 , pp. 1631-1641
    • Trzeciak, A.R.1    Barnes, J.2    Ejiogu, N.3    Foster, K.4    Brant, L.J.5    Zonderman, A.B.6    Evans, M.K.7
  • 66
    • 84864526811 scopus 로고    scopus 로고
    • Oxidative damage to DNA and single strand break repair capacity: Relationship to other measures of oxidative stress in a population cohort
    • Trzeciak A. R., Mohanty J. G., Jacob K. D., Oxidative damage to DNA and single strand break repair capacity: relationship to other measures of oxidative stress in a population cohort. Mutation Research 2012 736 1-2 93 103
    • (2012) Mutation Research , vol.736 , Issue.1-2 , pp. 93-103
    • Trzeciak, A.R.1    Mohanty, J.G.2    Jacob, K.D.3
  • 67
    • 0038204747 scopus 로고    scopus 로고
    • Age-related increases in plasma malondialdehyde and protein carbonyl levels and lymphocyte DNA damage in elderly subjects
    • DOI 10.1016/S0009-9120(03)00035-3
    • Mutlu-Türkolu Ü., Ilhan E., Öztezcan S., Kuru A., Ayka-Toker G., Uysal M., Age-related increases in plasma malondialdehyde and protein carbonyl levels and lymphocyte DNA damage in elderly subjects. Clinical Biochemistry 2003 36 5 397 400 2-s2.0-0038204747 10.1016/S0009-9120(03)00035-3 (Pubitemid 36776810)
    • (2003) Clinical Biochemistry , vol.36 , Issue.5 , pp. 397-400
    • Mutlu-Turkoglu, U.1    Ilhan, E.2    Oztezcan, S.3    Kuru, A.4    Aykac-Toker, G.5    Uysal, M.6
  • 68
    • 35048894272 scopus 로고    scopus 로고
    • Age-related increases in DNA repair and antioxidant protection: A comparison of the Boyd Orr Cohort of elderly subjects with a younger population sample
    • DOI 10.1093/ageing/afm107
    • Humphreys V., Martin R. M., Ratcliffe B., Duthie S., Wood S., Gunnell D., Collins A. R., Age-related increases in DNA repair and antioxidant protection: a comparison of the Boyd Orr Cohort of elderly subjects with a younger population sample. Age and Ageing 2007 36 5 521 526 2-s2.0-35048894272 10.1093/ageing/afm107 (Pubitemid 47554941)
    • (2007) Age and Ageing , vol.36 , Issue.5 , pp. 521-526
    • Humphreys, V.1    Martin, R.M.2    Ratcliffe, B.3    Duthie, S.4    Wood, S.5    Gunnell, D.6    Collins, A.R.7
  • 69
    • 32344448694 scopus 로고    scopus 로고
    • Assessment of reference values for DNA damage detected by the comet assay in human blood cell DNA
    • DOI 10.1016/j.mrrev.2005.10.001, PII S1383574205000591
    • Moller P., Assessment of reference values for DNA damage detected by the comet assay in human blood cell DNA. Mutation Research 2006 612 2 84 104 2-s2.0-32344448694 10.1016/j.mrrev.2005.10.001 (Pubitemid 43222095)
    • (2006) Mutation Research - Reviews in Mutation Research , vol.612 , Issue.2 , pp. 84-104
    • Moller, P.1
  • 70
    • 0036326014 scopus 로고    scopus 로고
    • Non-homologous DNA end joining in the mature rat brain
    • DOI 10.1046/j.0022-3042.2002.00776.x
    • Ren K., Pea De Ortiz S., Non-homologous DNA end joining in the mature rat brain. Journal of Neurochemistry 2002 80 6 949 959 2-s2.0-0036326014 10.1046/j.0022-3042.2002.00776.x (Pubitemid 34809947)
    • (2002) Journal of Neurochemistry , vol.80 , Issue.6 , pp. 949-959
    • Ren, K.1    Pena De Ortiz, S.2
  • 71
    • 28444474288 scopus 로고    scopus 로고
    • DNA double strand break repair in brain: Reduced NHEJ activity in aging rat neurons
    • DOI 10.1016/j.neulet.2005.09.053, PII S0304394005010888
    • Vyjayanti V. N., Rao K. S., DNA double strand break repair in brain: reduced NHEJ activity in aging rat neurons. Neuroscience Letters 2006 393 1 18 22 2-s2.0-28444474288 10.1016/j.neulet.2005.09.053 (Pubitemid 41739646)
    • (2006) Neuroscience Letters , vol.393 , Issue.1 , pp. 18-22
    • Vyjayanti, V.N.1    Rao, K.S.2
  • 72
    • 0032828150 scopus 로고    scopus 로고
    • Effect of age on DNA binding of the ku protein in irradiated human peripheral blood mononuclear cells (PBMC)
    • DOI 10.1016/S0531-5565(99)00026-1, PII S0515565099000261
    • Frasca D., Barattini P., Tirindelli D., Guidi L., Bartoloni C., Errani A., Costanzo M., Tricerri A., Pierelli L., Doria G., Effect of age on DNA binding of the ku protein in irradiated human peripheral blood mononuclear cells (PBMC). Experimental Gerontology 1999 34 5 645 658 2-s2.0-0032828150 10.1016/S0531-5565(99)00026-1 (Pubitemid 29421258)
    • (1999) Experimental Gerontology , vol.34 , Issue.5 , pp. 645-658
    • Frasca, D.1    Barattini, P.2    Tirindelli, D.3    Guidi, L.4    Bartoloni, C.5    Errani, A.6    Costanzo, M.7    Tricerri, A.8    Pierelli, L.9    Doria, G.10
  • 74
    • 0242585031 scopus 로고    scopus 로고
    • DNA damage recognition and repair capacities in human naïve and memory T cells from peripheral blood of young and elderly subjects
    • DOI 10.1016/S0047-6374(03)00030-7
    • Scarpaci S., Frasca D., Barattini P., Guidi L., Doria G., DNA damage recognition and repair capacities in human naïve and memory T cells from peripheral blood of young and elderly subjects. Mechanisms of Ageing and Development 2003 124 4 517 524 2-s2.0-0242585031 10.1016/S0047-6374(03)00030-7 (Pubitemid 36514907)
    • (2003) Mechanisms of Ageing and Development , vol.124 , Issue.4 , pp. 517-524
    • Scarpaci, S.1    Frasca, D.2    Barattini, P.3    Guidi, L.4    Doria, G.5
  • 76
    • 0033105094 scopus 로고    scopus 로고
    • Conserved domains in DNA repair proteins and evolution of repair systems
    • DOI 10.1093/nar/27.5.1223
    • Aravind L., Walker D. R., Koonin E. V., Conserved domains in DNA repair proteins and evolution of repair systems. Nucleic Acids Research 1999 27 5 1223 1242 2-s2.0-0033105094 10.1093/nar/27.5.1223 (Pubitemid 29206430)
    • (1999) Nucleic Acids Research , vol.27 , Issue.5 , pp. 1223-1242
    • Aravind, L.1    Walker, D.R.2    Koonin, E.V.3
  • 77
    • 0037115912 scopus 로고    scopus 로고
    • Enzymology of the repair of free radicals-induced DNA damage
    • DOI 10.1038/sj.onc.1206005
    • Gros L., Saparbaev M. K., Laval J., Enzymology of the repair of free radicals-induced DNA damage. Oncogene 2002 21 58 8905 8925 2-s2.0-0037115912 10.1038/sj.onc.1206005 (Pubitemid 36110821)
    • (2002) Oncogene , vol.21 , Issue.58 REV. ISS. 8 , pp. 8905-8925
    • Gros, L.1    Saparbaev, M.K.2    Laval, J.3
  • 78
    • 0024414264 scopus 로고
    • Molecular cloning of human uracil-DNA glycosylase, a highly conserved DNA repair enzyme
    • Olsen L. C., Aasland R., Wittwer C. U., Krokan H. E., Helland D. E., Molecular cloning of human uracil-DNA glycosylase, a highly conserved DNA repair enzyme. EMBO Journal 1989 8 10 3121 3125 2-s2.0-0024414264 (Pubitemid 19275013)
    • (1989) EMBO Journal , vol.8 , Issue.10 , pp. 3121-3125
    • Olsen, L.C.1    Aasland, R.2    Wittwer, C.U.3    Krokan, H.E.4    Helland, D.E.5
  • 79
    • 0030861915 scopus 로고    scopus 로고
    • DNA glycosylases in the base excision repair of DNA
    • Krokan H. E., Standal R., Slupphaug G., DNA glycosylases in the base excision repair of DNA. Biochemical Journal 1997 325 1 1 16 2-s2.0-0030861915 (Pubitemid 27322679)
    • (1997) Biochemical Journal , vol.325 , Issue.1 , pp. 1-16
    • Krokan, H.E.1    Standal, R.2    Slupphaug, G.3
  • 80
    • 67651001697 scopus 로고    scopus 로고
    • A potential impact of DNA repair on ageing and lifespan in the ageing model organism Podospora anserina: Decrease in mitochondrial DNA repair activity during ageing
    • 2-s2.0-67651001697 10.1016/j.mad.2009.05.003
    • Soerensen M., Gredilla R., Müller-Ohldach M., Werner A., Bohr V. A., Osiewacz H. D., Stevnsner T., A potential impact of DNA repair on ageing and lifespan in the ageing model organism Podospora anserina: decrease in mitochondrial DNA repair activity during ageing. Mechanisms of Ageing and Development 2009 130 8 487 496 2-s2.0-67651001697 10.1016/j.mad.2009.05.003
    • (2009) Mechanisms of Ageing and Development , vol.130 , Issue.8 , pp. 487-496
    • Soerensen, M.1    Gredilla, R.2    Müller-Ohldach, M.3    Werner, A.4    Bohr, V.A.5    Osiewacz, H.D.6    Stevnsner, T.7
  • 82
    • 77955888522 scopus 로고    scopus 로고
    • The role of oxidative stress in the aging process
    • 2-s2.0-77955888522 10.1100/tsw.2010.94
    • Oliveira B. F., Nogueira-Machado J. A., Chaves M. M., The role of oxidative stress in the aging process. The Scientific World Journal 2010 10 1121 1128 2-s2.0-77955888522 10.1100/tsw.2010.94
    • (2010) The Scientific World Journal , vol.10 , pp. 1121-1128
    • Oliveira, B.F.1    Nogueira-Machado, J.A.2    Chaves, M.M.3
  • 83
    • 40249084262 scopus 로고    scopus 로고
    • Longevity and resistance to stress correlate with DNA repair capacity in Caenorhabditis elegans
    • DOI 10.1093/nar/gkm1161
    • Hyun M., Lee J., Lee K., May A., Bohr V. A., Ahn B., Longevity and resistance to stress correlate with DNA repair capacity in Caenorhabditis elegans. Nucleic Acids Research 2008 36 4 1380 1389 2-s2.0-40249084262 10.1093/nar/gkm1161 (Pubitemid 351330952)
    • (2008) Nucleic Acids Research , vol.36 , Issue.4 , pp. 1380-1389
    • Hyun, M.1    Lee, J.2    Lee, K.3    May, A.4    Bohr, V.A.5    Ahn, B.6
  • 84
    • 34548853161 scopus 로고    scopus 로고
    • Decline of nucleotide excision repair capacity in aging Caenorhabditis elegans
    • DOI 10.1186/gb-2007-8-5-r70
    • Meyer J. N., Boyd W. A., Azzam G. A., Haugen A. C., Freedman J. H., Van Houten B., Decline of nucleotide excision repair capacity in aging Caenorhabditis elegans. Genome Biology 2007 8 5, article R70 2-s2.0-34548853161 10.1186/gb-2007-8-5-r70 (Pubitemid 351902771)
    • (2007) Genome Biology , vol.8 , Issue.5
    • Meyer, J.N.1    Boyd, W.A.2    Azzam, G.A.3    Haugen, A.C.4    Freedman, J.H.5    Van Houten, B.6
  • 85
    • 67349253020 scopus 로고    scopus 로고
    • Purification and characterization of Caenorhabditis elegans NTH, a homolog of human endonuclease III: Essential role of N-terminal region
    • 2-s2.0-67349253020 10.1016/j.dnarep.2009.04.020
    • Morinaga H., Yonekura S. I., Nakamura N., Sugiyama H., Yonei S., Zhang-Akiyama Q. M., Purification and characterization of Caenorhabditis elegans NTH, a homolog of human endonuclease III: essential role of N-terminal region. DNA Repair 2009 8 7 844 851 2-s2.0-67349253020 10.1016/j.dnarep.2009.04.020
    • (2009) DNA Repair , vol.8 , Issue.7 , pp. 844-851
    • Morinaga, H.1    Yonekura, S.I.2    Nakamura, N.3    Sugiyama, H.4    Yonei, S.5    Zhang-Akiyama, Q.M.6
  • 86
    • 54349125852 scopus 로고    scopus 로고
    • Podospora anserina: A model organism to study mechanisms of healthy ageing
    • 2-s2.0-54349125852 10.1007/s00438-008-0378-6
    • Scheckhuber C. Q., Osiewacz H. D., Podospora anserina: a model organism to study mechanisms of healthy ageing. Molecular Genetics and Genomics 2008 280 5 365 374 2-s2.0-54349125852 10.1007/s00438-008-0378-6
    • (2008) Molecular Genetics and Genomics , vol.280 , Issue.5 , pp. 365-374
    • Scheckhuber, C.Q.1    Osiewacz, H.D.2
  • 87
    • 0011555560 scopus 로고
    • Correlation between deoxyribonucleic acid excision repair and life span in a number of mammalian species
    • 2-s2.0-0011555560
    • Hart R. W., Setlow R. B., Correlation between deoxyribonucleic acid excision repair and life span in a number of mammalian species. Proceedings of the National Academy of Sciences of the United States of America 1974 71 6 2169 2173 2-s2.0-0011555560
    • (1974) Proceedings of the National Academy of Sciences of the United States of America , vol.71 , Issue.6 , pp. 2169-2173
    • Hart, R.W.1    Setlow, R.B.2
  • 88
    • 37349000601 scopus 로고    scopus 로고
    • Correlation of mitochondrial superoxide dismutase and DNA polymerase β in mammalian dermal fibroblasts with species maximal lifespan
    • DOI 10.1016/j.mad.2007.10.004, PII S0047637407001637
    • Brown M. F., Stuart J. A., Correlation of mitochondrial superoxide dismutase and DNA polymerase β in mammalian dermal fibroblasts with species maximal lifespan. Mechanisms of Ageing and Development 2007 128 11-12 696 705 2-s2.0-37349000601 10.1016/j.mad.2007.10.004 (Pubitemid 350299053)
    • (2007) Mechanisms of Ageing and Development , vol.128 , Issue.11-12 , pp. 696-705
    • Brown, M.F.1    Stuart, J.A.2
  • 89
    • 0036904776 scopus 로고    scopus 로고
    • Base excision repair capacity in mitochondria and nuclei: Tissue-specific variations
    • DOI 10.1096/fj.02-0463com
    • Karahalil B., Hogue B. A., De Souza-Pinto N. C., Bohr V. A., Base excision repair capacity in mitochondria and nuclei: tissue-specific variations. FASEB Journal 2002 16 14 1895 1902 2-s2.0-0036904776 10.1096/fj.02-0463com (Pubitemid 35462609)
    • (2002) FASEB Journal , vol.16 , Issue.14 , pp. 1895-1902
    • Karahalil, B.1    Hogue, B.A.2    De Souza-Pinto, N.C.3    Bohr, V.A.4
  • 91
    • 33847666362 scopus 로고    scopus 로고
    • Intracellular trafficking and regulation of mammalian AP-endonuclease 1 (APE1), an essential DNA repair protein
    • DOI 10.1016/j.dnarep.2006.10.010, PII S1568786406003193, Repair of small base lesions in DNA-from molecular biology to phenotype
    • Mitra S., Izumi T., Boldogh I., Bhakat K. K., Chattopadhyay R., Szczesny B., Intracellular trafficking and regulation of mammalian AP-endonuclease 1 (APE1), an essential DNA repair protein. DNA Repair 2007 6 4 461 469 2-s2.0-33847666362 10.1016/j.dnarep.2006.10.010 (Pubitemid 46357051)
    • (2007) DNA Repair , vol.6 , Issue.4 , pp. 461-469
    • Mitra, S.1    Izumi, T.2    Boldogh, I.3    Bhakat, K.K.4    Chattopadhyay, R.5    Szczesny, B.6
  • 92
    • 0033561246 scopus 로고    scopus 로고
    • Age-associated increase in 8-oxo-deoxyguanosine glycosylase/AP lyase activity in rat mitochondria
    • DOI 10.1093/nar/27.8.1935
    • Souza-Pinto N. C., Croteau D. L., Hudson E. K., Hansford R. G., Bohr V. A., Age-associated increase in 8-oxo-deoxyguanosine glycosylase/AP lyase activity in rat mitochondria. Nucleic Acids Research 1999 27 8 1935 1942 2-s2.0-0033561246 10.1093/nar/27.8.1935 (Pubitemid 29209638)
    • (1999) Nucleic Acids Research , vol.27 , Issue.8 , pp. 1935-1942
    • Souza-Pinto, N.C.1    Croteau, D.L.2    Hudson, E.K.3    Hansford, R.G.4    Bohr, V.A.5
  • 93
    • 0035871706 scopus 로고    scopus 로고
    • DNA repair and aging in mouse liver: 8-oxodG glycosylase activity increase in mitochondrial but not in nuclear extracts
    • DOI 10.1016/S0891-5849(01)00483-X, PII S089158490100483X
    • de Souza-Pinto N. C., Hogue B. A., Bohr V. A., DNA repair and aging in mouse liver: 8-oxodG glycosylase activity increase in mitochondrial but not in nuclear extracts. Free Radical Biology and Medicine 2001 30 8 916 923 2-s2.0-0035871706 10.1016/S0891-5849(01)00483-X (Pubitemid 32289269)
    • (2001) Free Radical Biology and Medicine , vol.30 , Issue.8 , pp. 916-923
    • De Souza-Pinto, N.C.1    Hogue, B.A.2    Bohr, V.A.3
  • 94
    • 0036316413 scopus 로고    scopus 로고
    • Age-dependent decline of DNA repair activity for oxidative lesions in rat brain mitochondria
    • DOI 10.1046/j.1471-4159.2002.00916.x
    • Chen D., Cao G., Hastings T., Feng Y., Pei W., O'Horo C., Chen J., Age-dependent decline of DNA repair activity for oxidative lesions in rat brain mitochondria. Journal of Neurochemistry 2002 81 6 1273 1284 2-s2.0-0036316413 10.1046/j.1471-4159.2002.00916.x (Pubitemid 34809261)
    • (2002) Journal of Neurochemistry , vol.81 , Issue.6 , pp. 1273-1284
    • Chen, D.1    Cao, G.2    Hastings, T.3    Feng, Y.4    Pei, W.5    O'Horo, C.6    Chen, J.7
  • 95
    • 33744912521 scopus 로고    scopus 로고
    • Mitochondrial and nuclear DNA-repair capacity of various brain regions in mouse is altered in an age-dependent manner
    • DOI 10.1016/j.neurobiolaging.2005.06.002, PII S0197458005001739
    • Imam S. Z., Karahalil B., Hogue B. A., Souza-Pinto N. C., Bohr V. A., Mitochondrial and nuclear DNA-repair capacity of various brain regions in mouse is altered in an age-dependent manner. Neurobiology of Aging 2006 27 8 1129 1136 2-s2.0-33744912521 10.1016/j.neurobiolaging.2005.06.002 (Pubitemid 43850641)
    • (2006) Neurobiology of Aging , vol.27 , Issue.8 , pp. 1129-1136
    • Imam, S.Z.1    Karahalil, B.2    Hogue, B.A.3    Souza-Pinto, N.C.4    Bohr, V.A.5
  • 96
    • 77951978898 scopus 로고    scopus 로고
    • Differential age-related changes in mitochondrial DNA repair activities in mouse brain regions
    • 2-s2.0-77951978898 10.1016/j.neurobiolaging.2008.07.004
    • Gredilla R., Garm C., Holm R., Bohr V. A., Stevnsner T., Differential age-related changes in mitochondrial DNA repair activities in mouse brain regions. Neurobiology of Aging 2010 31 6 993 1002 2-s2.0-77951978898 10.1016/j.neurobiolaging.2008.07.004
    • (2010) Neurobiology of Aging , vol.31 , Issue.6 , pp. 993-1002
    • Gredilla, R.1    Garm, C.2    Holm, R.3    Bohr, V.A.4    Stevnsner, T.5
  • 97
    • 34247156564 scopus 로고    scopus 로고
    • DNA repair, mitochondria, and neurodegeneration
    • DOI 10.1016/j.neuroscience.2006.08.061, PII S0306452206011730, Genome Dynamics and DNA Repair in the CNS
    • Weissman L., de Souza-Pinto N. C., Stevnsner T., Bohr V. A., DNA repair, mitochondria, and neurodegeneration. Neuroscience 2007 145 4 1318 1329 2-s2.0-34247156564 10.1016/j.neuroscience.2006.08.061 (Pubitemid 46602727)
    • (2007) Neuroscience , vol.145 , Issue.4 , pp. 1318-1329
    • Weissman, L.1    De Souza-Pinto, N.C.2    Stevnsner, T.3    Bohr, V.A.4
  • 98
    • 3242662612 scopus 로고    scopus 로고
    • Nitrogen disruption of synaptoneurosomes: An alternative method to isolate brain mitochondria
    • DOI 10.1016/j.jneumeth.2004.02.028, PII S0165027004001001
    • Brown M. R., Sullivan P. G., Dorenbos K. A., Modafferi E. A., Geddes J. W., Steward O., Nitrogen disruption of synaptoneurosomes: an alternative method to isolate brain mitochondria. Journal of Neuroscience Methods 2004 137 2 299 303 2-s2.0-3242662612 10.1016/j.jneumeth.2004.02.028 (Pubitemid 38942894)
    • (2004) Journal of Neuroscience Methods , vol.137 , Issue.2 , pp. 299-303
    • Brown, M.R.1    Sullivan, P.G.2    Dorenbos, K.A.3    Modafferi, E.A.4    Geddes, J.W.5    Steward, O.6
  • 99
    • 0029916343 scopus 로고    scopus 로고
    • Mitochondrial electron transport chain activities and DNA deletions in regions of the rat brain
    • DOI 10.1016/0047-6374(96)01696-X
    • Filburn C. R., Edris W., Tamatani M., Hogue B., Kudryashova I., Hansford R. G., Mitochondrial electron transport chain activities and DNA deletions in regions of the rat brain. Mechanisms of Ageing and Development 1996 87 1 35 46 2-s2.0-0029916343 10.1016/0047-6374(96)01696-X (Pubitemid 26142429)
    • (1996) Mechanisms of Ageing and Development , vol.87 , Issue.1 , pp. 35-46
    • Filburn, C.R.1    Edris, W.2    Tamatani, M.3    Hogue, B.4    Kudryashova, I.5    Hansford, R.G.6
  • 100
    • 34848813841 scopus 로고    scopus 로고
    • Differential temporal response of hippocampus, cortex and cerebellum to hypobaric hypoxia: A biochemical approach
    • DOI 10.1016/j.neuint.2007.04.003, PII S0197018607000800
    • Hota S. K., Barhwal K., Singh S. B., Ilavazhagan G., Differential temporal response of hippocampus, cortex and cerebellum to hypobaric hypoxia: a biochemical approach. Neurochemistry International 2007 51 6-7 384 390 2-s2.0-34848813841 10.1016/j.neuint.2007.04.003 (Pubitemid 47503459)
    • (2007) Neurochemistry International , vol.51 , Issue.6-7 , pp. 384-390
    • Hota, S.K.1    Barhwal, K.2    Singh, S.B.3    Ilavazhagan, G.4
  • 101
    • 84856969873 scopus 로고    scopus 로고
    • Mitochondrial base excision repair in mouse synaptosomes during normal aging and in a model of Alzheimer's disease
    • 2-s2.0-77955383091 10.1016/j.neurobiolaging.2010.06.019
    • Gredilla R., Weissman L., Yang J. L., Bohr V. A., Stevnsner T., Mitochondrial base excision repair in mouse synaptosomes during normal aging and in a model of Alzheimer's disease. Neurobiology of Aging 2010 33 4 694 707 2-s2.0-77955383091 10.1016/j.neurobiolaging.2010.06.019
    • (2010) Neurobiology of Aging , vol.33 , Issue.4 , pp. 694-707
    • Gredilla, R.1    Weissman, L.2    Yang, J.L.3    Bohr, V.A.4    Stevnsner, T.5
  • 102
    • 0038458979 scopus 로고    scopus 로고
    • Targeting human 8-oxoguanine glycosylase to mitochondria of oligodendrocytes protects against menadione-induced oxidative stress
    • DOI 10.1002/glia.10230
    • Druzhyna N. M., Hollensworth S. B., Kelley M. R., Wilson G. L., LeDoux S. P., Targeting human 8-oxoguanine glycosylase to mitochondria of oligodendrocytes protects against menadione-induced oxidative stress. GLIA 2003 42 4 370 378 2-s2.0-0038458979 10.1002/glia.10230 (Pubitemid 36702277)
    • (2003) GLIA , vol.42 , Issue.4 , pp. 370-378
    • Druzhyna, N.M.1    Hollensworth, S.B.2    Kelley, M.R.3    Wilson, G.L.4    LeDoux, S.P.5
  • 103
    • 34548802393 scopus 로고    scopus 로고
    • Defective DNA base excision repair in brain from individuals with Alzheimer's disease and amnestic mild cognitive impairment
    • DOI 10.1093/nar/gkm605
    • Weissman L., Jo D. G., Sorensen M. M., de Souza-Pinto N. C., Markesbery W. R., Mattson M. P., Bohr V. A., Defective DNA base excision repair in brain from individuals with Alzheimer's disease and amnestic mild cognitive impairment. Nucleic Acids Research 2007 35 16 5545 5555 2-s2.0-34548802393 10.1093/nar/gkm605 (Pubitemid 47423927)
    • (2007) Nucleic Acids Research , vol.35 , Issue.16 , pp. 5545-5555
    • Weissman, L.1    Jo, D.-G.2    Sorensen, M.M.3    De Souza-Pinto, N.C.4    Markesbery, W.R.5    Mattson, M.P.6    Bohr, V.A.7
  • 104
    • 77953036663 scopus 로고    scopus 로고
    • Age- and tissue-specific changes in mitochondrial and nuclear DNA base excision repair activity in mice: Susceptibility of skeletal muscles to oxidative injury
    • 2-s2.0-77953036663 10.1016/j.mad.2010.03.009
    • Szczesny B., Tann A. W., Mitra S., Age- and tissue-specific changes in mitochondrial and nuclear DNA base excision repair activity in mice: susceptibility of skeletal muscles to oxidative injury. Mechanisms of Ageing and Development 2010 131 5 330 337 2-s2.0-77953036663 10.1016/j.mad.2010.03.009
    • (2010) Mechanisms of Ageing and Development , vol.131 , Issue.5 , pp. 330-337
    • Szczesny, B.1    Tann, A.W.2    Mitra, S.3
  • 105
    • 0030885350 scopus 로고    scopus 로고
    • Mitochondrial DNA rearrangements of Podospora anserina are under the control of the nuclear gene grisea
    • DOI 10.1073/pnas.94.20.10768
    • Borghouts C., Kimpel E., Osiewacz H. D., Mitochondrial DNA rearrangements of Podospora anserina are under the control of the nuclear gene grisea. Proceedings of the National Academy of Sciences of the United States of America 1997 94 20 10768 10773 2-s2.0-0030885350 10.1073/pnas.94.20.10768 (Pubitemid 27430809)
    • (1997) Proceedings of the National Academy of Sciences of the United States of America , vol.94 , Issue.20 , pp. 10768-10773
    • Borghouts, C.1    Kimpel, E.2    Osiewacz, H.D.3
  • 106
    • 0031720426 scopus 로고    scopus 로고
    • A murine AP-endonuclease gene-targeted deficiency with post-implantation embryonic progression and ionizing radiation sensitivity
    • DOI 10.1016/S0921-8777(98)00039-1
    • Ludwig D. L., MacInnes M. A., Takiguchi Y., Purtymun P. E., Henrie M., Flannery M., Meneses J., Pedersen R. A., Chen D. J., A murine AP-endonuclease gene-targeted deficiency with post-implantation embryonic progression and ionizing radiation sensitivity. Mutation Research 1998 409 1 17 29 2-s2.0-0031720426 10.1016/S0921-8777(98)00039-1 (Pubitemid 28467991)
    • (1998) Mutation Research - DNA Repair , vol.409 , Issue.1 , pp. 17-29
    • Ludwig, D.L.1    MacInnes, M.A.2    Takiguchi, Y.3    Purtymun, P.E.4    Henrie, M.5    Flannery, M.6    Meneses, J.7    Pedersen, R.A.8    Chen, D.J.9
  • 107
    • 26444432919 scopus 로고    scopus 로고
    • Mitochondrial DNA polymerase gamma is essential for mammalian embryogenesis
    • DOI 10.1093/hmg/ddi184
    • Hance N., Ekstrand M. I., Trifunovic A., Mitochondrial DNA polymerase gamma is essential for mammalian embryogenesis. Human Molecular Genetics 2005 14 13 1775 1783 2-s2.0-26444432919 10.1093/hmg/ddi184 (Pubitemid 41418049)
    • (2005) Human Molecular Genetics , vol.14 , Issue.13 , pp. 1775-1783
    • Hance, N.1    Ekstrand, M.I.2    Trifunovic, A.3
  • 108
    • 33646589977 scopus 로고    scopus 로고
    • Early embryonic lethality due to targeted inactivation of DNA ligase III
    • DOI 10.1128/MCB.26.10.3935-3941.2006
    • Puebla-Osorio N., Lacey D. B., Alt F. W., Zhu C., Early embryonic lethality due to targeted inactivation of DNA ligase III. Molecular and Cellular Biology 2006 26 10 3935 3941 2-s2.0-33646589977 10.1128/MCB.26.10.3935-3941. 2006 (Pubitemid 43726408)
    • (2006) Molecular and Cellular Biology , vol.26 , Issue.10 , pp. 3935-3941
    • Puebla-Osorio, N.1    Lacey, D.B.2    Alt, F.W.3    Zhu, C.4
  • 111
    • 67349140639 scopus 로고    scopus 로고
    • Targeted deletion of the genes encoding NTH1 and NEIL1 DNA N-glycosylases reveals the existence of novel carcinogenic oxidative damage to DNA
    • 2-s2.0-67349140639 10.1016/j.dnarep.2009.03.001
    • Chan M. K., Ocampo-Hafalla M. T., Vartanian V., Jaruga P., Kirkali G., Koenig K. L., Brown S., Lloyd R. S., Dizdaroglu M., Teebor G. W., Targeted deletion of the genes encoding NTH1 and NEIL1 DNA N-glycosylases reveals the existence of novel carcinogenic oxidative damage to DNA. DNA Repair 2009 8 7 786 794 2-s2.0-67349140639 10.1016/j.dnarep.2009.03.001
    • (2009) DNA Repair , vol.8 , Issue.7 , pp. 786-794
    • Chan, M.K.1    Ocampo-Hafalla, M.T.2    Vartanian, V.3    Jaruga, P.4    Kirkali, G.5    Koenig, K.L.6    Brown, S.7    Lloyd, R.S.8    Dizdaroglu, M.9    Teebor, G.W.10
  • 112
    • 36849088515 scopus 로고    scopus 로고
    • Deletion of Ku70, Ku80, or both causes early aging without substantially increased cancer
    • DOI 10.1128/MCB.00785-07
    • Li H., Vogel H., Holcomb V. B., Gu Y., Hasty P., Deletion of Ku70, Ku80, or both causes early aging without substantially increased cancer. Molecular and Cellular Biology 2007 27 23 8205 8214 2-s2.0-36849088515 10.1128/MCB.00785-07 (Pubitemid 350234234)
    • (2007) Molecular and Cellular Biology , vol.27 , Issue.23 , pp. 8205-8214
    • Li, H.1    Vogel, H.2    Holcomb, V.B.3    Gu, Y.4    Hasty, P.5
  • 113
    • 79960394750 scopus 로고    scopus 로고
    • Physiological consequences of defects in ERCC1-XPF DNA repair endonuclease
    • 2-s2.0-79960394750 10.1016/j.dnarep.2011.04.026
    • Gregg S. Q., Robinson A. R., Niedernhofer L. J., Physiological consequences of defects in ERCC1-XPF DNA repair endonuclease. DNA Repair 2011 10 7 781 791 2-s2.0-79960394750 10.1016/j.dnarep.2011.04.026
    • (2011) DNA Repair , vol.10 , Issue.7 , pp. 781-791
    • Gregg, S.Q.1    Robinson, A.R.2    Niedernhofer, L.J.3
  • 114
    • 79960341941 scopus 로고    scopus 로고
    • Premature aging and cancer in nucleotide excision repair-disorders
    • 2-s2.0-79960341941 10.1016/j.dnarep.2011.04.025
    • Diderich K., Alanazi M., Hoeijmakers J. H. J., Premature aging and cancer in nucleotide excision repair-disorders. DNA Repair 2011 10 7 772 780 2-s2.0-79960341941 10.1016/j.dnarep.2011.04.025
    • (2011) DNA Repair , vol.10 , Issue.7 , pp. 772-780
    • Diderich, K.1    Alanazi, M.2    Hoeijmakers, J.H.J.3
  • 117
    • 33847245332 scopus 로고    scopus 로고
    • The role of mitochondrial DNA mutations in mammalian aging
    • ARTICLE E24 2-s2.0-34147181042 10.1371/journal.pgen.0030024
    • Kujoth G. C., Bradshaw P. C., Haroon S., Prolla T. A., The role of mitochondrial DNA mutations in mammalian aging. PLoS Genetics 2007 3 2, article e24 2-s2.0-34147181042 10.1371/journal.pgen.0030024
    • (2007) PLoS Genetics , vol.3 , Issue.2
    • Kujoth, G.C.1    Bradshaw, P.C.2    Haroon, S.3    Prolla, T.A.4
  • 118
    • 57349098450 scopus 로고    scopus 로고
    • Somatic mtDNA mutations and agingfacts and fancies
    • 2-s2.0-57349098450 10.1016/j.exger.2008.05.006
    • Kukat A., Trifunovic A., Somatic mtDNA mutations and agingfacts and fancies. Experimental Gerontology 2009 44 1-2 101 105 2-s2.0-57349098450 10.1016/j.exger.2008.05.006
    • (2009) Experimental Gerontology , vol.44 , Issue.1-2 , pp. 101-105
    • Kukat, A.1    Trifunovic, A.2
  • 119
    • 77953630947 scopus 로고    scopus 로고
    • The mtDNA mutator mouse: Dissecting mitochondrial involvement in aging
    • 2-s2.0-77953630947
    • Edgar D., Trifunovic A., The mtDNA mutator mouse: dissecting mitochondrial involvement in aging. Aging 2009 1 12 1028 1032 2-s2.0-77953630947
    • (2009) Aging , vol.1 , Issue.12 , pp. 1028-1032
    • Edgar, D.1    Trifunovic, A.2
  • 120
    • 70450121949 scopus 로고    scopus 로고
    • On mitochondria, mutations, and methodology
    • ARTICLE 437 2-s2.0-70450121949 10.1016/j.cmet.2009.11.001
    • Vermulst M., Wanagat J., Loeb L. A., On mitochondria, mutations, and methodology. Cell Metabolism 2009 10 6, article 437 2-s2.0-70450121949 10.1016/j.cmet.2009.11.001
    • (2009) Cell Metabolism , vol.10 , Issue.6
    • Vermulst, M.1    Wanagat, J.2    Loeb, L.A.3
  • 121
    • 80053117501 scopus 로고    scopus 로고
    • The excitatory neurotransmitter glutamate stimulates DNA repair to increase neuronal resiliency
    • 2-s2.0-79960129921 10.1016/j.mad.2011.06.005
    • Yang J. L., Sykora P., Wilson D. M. III, Mattson M. P., Bohr V. A., The excitatory neurotransmitter glutamate stimulates DNA repair to increase neuronal resiliency. Mechanisms of Ageing and Development 2011 132 89 405 411 2-s2.0-79960129921 10.1016/j.mad.2011.06.005
    • (2011) Mechanisms of Ageing and Development , vol.132 , Issue.89 , pp. 405-411
    • Yang, J.L.1    Sykora, P.2    Wilson III, D.M.3    Mattson, M.P.4    Bohr, V.A.5
  • 122
    • 70349852936 scopus 로고    scopus 로고
    • DNA base excision repair activities in mouse models of Alzheimer's disease
    • 2-s2.0-70349852936 10.1016/j.neurobiolaging.2008.02.014
    • Weissman L., de Souza-Pinto N. C., Mattson M. P., Bohr V. A., DNA base excision repair activities in mouse models of Alzheimer's disease. Neurobiology of Aging 2009 30 12 2080 2081 2-s2.0-70349852936 10.1016/j.neurobiolaging.2008. 02.014
    • (2009) Neurobiology of Aging , vol.30 , Issue.12 , pp. 2080-2081
    • Weissman, L.1    De Souza-Pinto, N.C.2    Mattson, M.P.3    Bohr, V.A.4
  • 125
    • 79960328293 scopus 로고    scopus 로고
    • Cockayne syndrome B protein antagonizes OGG1 in modulating CAG repeat length in vivo
    • Kovtun I. V., Johnson K. O., McMurray C. T., Cockayne syndrome B protein antagonizes OGG1 in modulating CAG repeat length in vivo. Aging 2011 3 5 509 514
    • (2011) Aging , vol.3 , Issue.5 , pp. 509-514
    • Kovtun, I.V.1    Johnson, K.O.2    McMurray, C.T.3
  • 126
    • 74249102052 scopus 로고    scopus 로고
    • Stoichiometry of base excision repair proteins correlates with increased somatic CAG instability in striatum over cerebellum in Huntington's disease transgenic mice
    • 2-s2.0-74249102052 10.1371/journal.pgen.1000749 e1000749
    • Goula A. V., Berquist B. R., Wilson D. M. III, Wheeler V. C., Trottier Y., Merienne K., Stoichiometry of base excision repair proteins correlates with increased somatic CAG instability in striatum over cerebellum in Huntington's disease transgenic mice. PLoS Genetics 2009 5 12 2-s2.0-74249102052 10.1371/journal.pgen.1000749 e1000749
    • (2009) PLoS Genetics , vol.5 , Issue.12
    • Goula, A.V.1    Berquist, B.R.2    Wilson III, D.M.3    Wheeler, V.C.4    Trottier, Y.5    Merienne, K.6
  • 127
    • 10044225528 scopus 로고    scopus 로고
    • Rare diseases provide rare insights into DNA repair pathways, TFIIH, aging and cancer
    • DOI 10.1016/j.dnarep.2004.09.010, PII S1568786404002903
    • Bohr V. A., Sander M., Kraemer K. H., Rare diseases provide rare insights into DNA repair pathways, TFIIH, aging and cancer. DNA Repair 2005 4 2 293 302 2-s2.0-10044225528 10.1016/j.dnarep.2004.09.010 (Pubitemid 39601419)
    • (2005) DNA Repair , vol.4 , Issue.2 , pp. 293-302
    • Bohr, V.A.1    Sander, M.2    Kraemer, K.H.3
  • 128
    • 45449093552 scopus 로고    scopus 로고
    • The role of Cockayne Syndrome group B (CSB) protein in base excision repair and aging
    • 2-s2.0-45449093552 10.1016/j.mad.2008.04.009
    • Stevnsner T., Muftuoglu M., Aamann M. D., Bohr V. A., The role of Cockayne Syndrome group B (CSB) protein in base excision repair and aging. Mechanisms of Ageing and Development 2008 129 7-8 441 448 2-s2.0-45449093552 10.1016/j.mad.2008.04.009
    • (2008) Mechanisms of Ageing and Development , vol.129 , Issue.7-8 , pp. 441-448
    • Stevnsner, T.1    Muftuoglu, M.2    Aamann, M.D.3    Bohr, V.A.4
  • 129
    • 0033105926 scopus 로고    scopus 로고
    • Repair of 8-oxoguanine in DNA is deficient in Cockayne syndrome group B cells
    • DOI 10.1093/nar/27.5.1365
    • Dianov G., Bischoff C., Sunesen M., Bohr V. A., Repair of 8-oxoguanine in DNA is deficient in Cockayne syndrome group B cells. Nucleic Acids Research 1999 27 5 1365 1368 2-s2.0-0033105926 10.1093/nar/27.5.1365 (Pubitemid 29206448)
    • (1999) Nucleic Acids Research , vol.27 , Issue.5 , pp. 1365-1368
    • Dianov, G.1    Bischoff, C.2    Sunesen, M.3    Bohr, V.A.4
  • 131
    • 65349127253 scopus 로고    scopus 로고
    • Accumulation of mitochondrial DNA damage and bioenergetic dysfunction in CSB defective cells
    • 2-s2.0-65349127253 10.1111/j.1742-4658.2009.07004.x
    • Osenbroch P. O., Auk-Emblem P., Halsne R., Strand J., Forstrom R. J., Van Der Pluijm I., Eide L., Accumulation of mitochondrial DNA damage and bioenergetic dysfunction in CSB defective cells. FEBS Journal 2009 276 10 2811 2821 2-s2.0-65349127253 10.1111/j.1742-4658.2009.07004.x
    • (2009) FEBS Journal , vol.276 , Issue.10 , pp. 2811-2821
    • Osenbroch, P.O.1    Auk-Emblem, P.2    Halsne, R.3    Strand, J.4    Forstrom, R.J.5    Van Der Pluijm, I.6    Eide, L.7
  • 133
    • 84861749572 scopus 로고    scopus 로고
    • Cockayne syndrome group B protein prevents the accumulation of damaged mitochondria by promoting mitochondrial autophagy
    • Scheibye-Knudsen M., Ramamoorthy M., Sykora P., Cockayne syndrome group B protein prevents the accumulation of damaged mitochondria by promoting mitochondrial autophagy. Journal of Experimental Medicine 2012 209 4 855 869
    • (2012) Journal of Experimental Medicine , vol.209 , Issue.4 , pp. 855-869
    • Scheibye-Knudsen, M.1    Ramamoorthy, M.2    Sykora, P.3
  • 134
    • 76749168005 scopus 로고    scopus 로고
    • Roles of Werner syndrome protein in protection of genome integrity
    • 2-s2.0-76749168005 10.1016/j.dnarep.2009.12.011
    • Rossi M. L., Ghosh A. K., Bohr V. A., Roles of Werner syndrome protein in protection of genome integrity. DNA Repair 2010 9 3 331 344 2-s2.0-76749168005 10.1016/j.dnarep.2009.12.011
    • (2010) DNA Repair , vol.9 , Issue.3 , pp. 331-344
    • Rossi, M.L.1    Ghosh, A.K.2    Bohr, V.A.3
  • 135
    • 67349230444 scopus 로고    scopus 로고
    • Roles of RECQ helicases in recombination based DNA repair, genomic stability and aging
    • 2-s2.0-67349230444 10.1007/s10522-008-9205-z
    • Singh D. K., Ahn B., Bohr V. A., Roles of RECQ helicases in recombination based DNA repair, genomic stability and aging. Biogerontology 2009 10 3 235 252 2-s2.0-67349230444 10.1007/s10522-008-9205-z
    • (2009) Biogerontology , vol.10 , Issue.3 , pp. 235-252
    • Singh, D.K.1    Ahn, B.2    Bohr, V.A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.