The commitment of human cells to senescence

Aging: Facts and Theories

Volumn 39, Issue , 2014, Pages 1-7

  Holliday, Robin ^a  

^a Australian Academy of Science   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 84925842236     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1159/000358896     Document Type: Chapter

References (19)

1. Hayflick L, Moorhead PS: The serial cultivation of human diploid cell strains. Exp Cell Res 1961;25: 585-621.
2. Hayflick L: The limited in vitro lifespan of human diploid cell strains. Exp Cell Res 1965;37: 614-636.
3. Holliday R, Huschtscha LI, Tarrant GL, Kirkwood TBL: Testing the commitment theory of cellular aging. Science 1977;198: 366-372.
4. Kirkwood TBL, Holliday R: Commitment to senescence: a model for the finite and infinite growth of human fibroblasts in culture. J Theoret Biol 1973;53: 481-496.
5. Holliday R, Huschtscha LI, Kirkwood TBL: Further evidence for the commitment theory of cellular aging. Science 1981;213: 1505-1508.
6. Martin GM, Curtis A, Sprague BS, Epstein CJ: Replicative lifespan of cultivated human cells: effects of donor's age, tissue and genotype. Lab Invest 1970;23: 86-92.
7. Maier AB, Westendorp RJC: Relationship between replicative senescence of human fibroblasts and life history characteristics. Ageing Res Rev 2009;8: 237-245.
8. Cristofalo VJ, Allen RG, Pignolo, RJ, Martin BJ, Beck JC: Relationship between donor age and replicative lifespan of human cells in culture: a re-evaluation. Proc Natl Acad Sci 1998;95: 10614-10619.
9. Zavala C, Herner G, Fialkow PF: Evidence for selection in cultured diploid fibroblast strains. Exp Cell Res 1978;117: 137-141.
10. McCarron M, Osborne, Y, Storey CJ, Dempsey JL, Turner DR, Morley AA: Effect of age on lymphocyte proliferation. Mech Age Dev 1987;41: 211-218.
11. Reddel R: A Re-assessment of the telomere hypothesis of senescence. Bioessays 1998;20: 977-984.
12. Baird DM: Telomeres. Exp Gerontol 2006;41: 1223-1227.
13. Baird DM: Telomeres 11. Exp Gerontol 2008;43: 15-19.
14. Holliday R: Telomeres and telomerase: the commitment theory of cellular ageing revisited. Sci Prog 2012;95: 199-205.
15. Wilson VL, Jones PA: DNA methylation decreases in aging but not in immortal cells. Science 1983;220: 1055-1057.
16. Holliday R: Strong effects of 5-azacytidine on the in vitro lifespan of diploid human fibroblasts. Exp Cell Res 1986;166: 543-552.
17. Fairweather DS, Fox M, Margison GP: The in vitro lifespan of MRC-5 cells is shortened by 5-azacytidine induced demethylation. Exp Cell Res 1987;168: 153-159.
18. Koch CM, Joussen S, Schellenberg A, Lin Q, Zenke M, Wagner W: Monitoring of cellular senescence by DNA-methylation at specific CpG sites. Aging Cell 2012;11: 366-369.
19. Todaro GJ, Green H: Quantitative studies of the growth of mouse embryo cells in culture and their development into established lines. J Cell Biol 1963;17: 299-313.