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Volumn 119, Issue 6, 2012, Pages 1490-1500

Mitochondrial dysfunction in ataxia-telangiectasia

Author keywords

[No Author keywords available]

Indexed keywords

ATM PROTEIN; BECLIN 1; REACTIVE OXYGEN METABOLITE;

EID: 84856893251     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2011-08-373639     Document Type: Article
Times cited : (318)

References (48)
  • 1
    • 0030218023 scopus 로고    scopus 로고
    • Ataxia-telangiectasia: A multifaceted genetic disorder associated with defective signal transduction
    • DOI 10.1016/S0952-7915(96)80030-6
    • Lavin MF, Shiloh Y. Ataxia-telangiectasia - a multifaceted genetic disorder associated with defective signal transduction. Curr Opin Immunol. 1996;8:459-464. (Pubitemid 26280771)
    • (1996) Current Opinion in Immunology , vol.8 , Issue.4 , pp. 459-464
    • Lavin, M.F.1    Shiloh, Y.2
  • 2
    • 0032524070 scopus 로고    scopus 로고
    • Requirement for Atm in ionizing radiation-induced cell death in the developing central nervous system
    • DOI 10.1126/science.280.5366.1089
    • Herzog K-H, Chong MJ, Kapsetaki M, Morgan JI, McKinnon PJ. Requirement for Atm in ionizing radiation-induced cell death in the developing central nervous system. Science. 1998;280:1089-1091. (Pubitemid 28234952)
    • (1998) Science , vol.280 , Issue.5366 , pp. 1089-1091
    • Herzog, K.-H.1    Chong, M.J.2    Kapsetaki, M.3    Morgan, J.I.4    McKinnon, P.J.5
  • 4
    • 52449114574 scopus 로고    scopus 로고
    • Ataxia-telangiectasia: From a rare disorder to a paradigm for cell signalling and cancer
    • Lavin MF. Ataxia-telangiectasia: from a rare disorder to a paradigm for cell signalling and cancer. Nat Rev Mol Cell Biol. 2008;9(10):759-769.
    • (2008) Nat Rev Mol Cell Biol , vol.9 , Issue.10 , pp. 759-769
    • Lavin, M.F.1
  • 5
    • 77955847245 scopus 로고    scopus 로고
    • Multiple roles of ATM in monitoring and maintaining DNA integrity
    • Derheimer FA, Kastan MB. Multiple roles of ATM in monitoring and maintaining DNA integrity. FEBS Lett. 2010;584(17):3675-3681.
    • (2010) FEBS Lett , vol.584 , Issue.17 , pp. 3675-3681
    • Derheimer, F.A.1    Kastan, M.B.2
  • 6
    • 0033662156 scopus 로고    scopus 로고
    • Participation of ATM in insulin signalling through phosphorylation of eIF-4E binding protein 1 (4E-BP1)
    • Yang D, Kastan MB. Participation of ATM in insulin signalling through phosphorylation of eIF-4E binding protein 1 (4E-BP1). Nat Cell Biol. 2000;2: 893-898.
    • (2000) Nat Cell Biol , vol.2 , pp. 893-898
    • Yang, D.1    Kastan, M.B.2
  • 11
    • 33645730667 scopus 로고    scopus 로고
    • Reactive oxygen species act through p38 MAPK to limit the lifespan of hematopoietic stem cells
    • Ito K, Hirao A, Arai F, et al. Reactive oxygen species act through p38 MAPK to limit the lifespan of hematopoietic stem cells. Nat Med. 2006;12(4): 446-451.
    • (2006) Nat Med , vol.12 , Issue.4 , pp. 446-451
    • Ito, K.1    Hirao, A.2    Arai, F.3
  • 14
    • 0036012789 scopus 로고    scopus 로고
    • ATM deficiency and oxidative stress: A new dimension of defective response to DNA damage
    • DOI 10.1016/S1568-7864(01)00007-6, PII S1568786401000076
    • Barzilai A, Rotman G, Shiloh Y. ATM deficiency and oxidative stress: a new kimension of defective response to DNA damage. DNA Repair. 2002;1:3-25. (Pubitemid 34475690)
    • (2002) DNA Repair , vol.1 , Issue.1 , pp. 3-25
    • Barzilai, A.1    Rotman, G.2    Shiloh, Y.3
  • 15
    • 0035266308 scopus 로고    scopus 로고
    • Increased oxidative stress in ataxia telangiectasia evidenced by alterations in redox state of brains from Atm-deficient mice
    • Kamsler A, Daily D, Hochman A, et al. Increased oxidative stress in ataxia telangiectasia evidenced by alterations in redox state of brains from Atm-deficient mice. Cancer Res. 2001;61(5): 1849-1854. (Pubitemid 32691998)
    • (2001) Cancer Research , vol.61 , Issue.5 , pp. 1849-1854
    • Kamsler, A.1    Daily, D.2    Hochman, A.3    Stern, N.4    Shiloh, Y.5    Rotman, G.6    Barzilai, A.7
  • 17
    • 30344432706 scopus 로고    scopus 로고
    • Role of mitochondrial DNA in toxic responses to oxidative stress
    • DOI 10.1016/j.dnarep.2005.03.002, PII S1568786405000546
    • Van Houten B, Woshner V, Santos JH. Role of mitochondrial DNA in toxic responses to oxidative stress. DNA Repair. 2006;5(2):145-152. (Pubitemid 43069515)
    • (2006) DNA Repair , vol.5 , Issue.2 , pp. 145-152
    • Van Houten, B.1    Woshner, V.2    Santos, J.H.3
  • 18
    • 77953500851 scopus 로고    scopus 로고
    • Mitochondrial dysfunction in neurodegenerative diseases and cancer
    • de Moura MB, dos Santos LS, Van HB. Mitochondrial dysfunction in neurodegenerative diseases and cancer. Environ Mol Mutagen. 2010;51(5): 391-405.
    • (2010) Environ Mol Mutagen , vol.51 , Issue.5 , pp. 391-405
    • De Moura, M.B.1    Dos Santos, L.S.2    Van, H.B.3
  • 19
    • 34848835736 scopus 로고    scopus 로고
    • Ataxia-telangiectasia mutated kinase regulates ribonucleotide reductase and mitochondrial homeostasis
    • DOI 10.1172/JCI31604
    • Eaton JS, Lin ZP, Sartorelli AC, Bonawitz ND, Shadel GS. Ataxia-telangiectasia mutated kinase regulates ribonucleotide reductase and mitochondrial homeostasis. J Clin Invest. 2007;117(9): 2723-2734. (Pubitemid 47494372)
    • (2007) Journal of Clinical Investigation , vol.117 , Issue.9 , pp. 2723-2734
    • Eaton, J.S.1    Lin, Z.P.2    Sartorelli, A.C.3    Bonawitz, N.D.4    Shadel, G.S.5
  • 20
    • 34548430918 scopus 로고    scopus 로고
    • Intrinsic mitochondrial dysfunction in ATM-deficient lymphoblastoid cells
    • DOI 10.1093/hmg/ddm166
    • Ambrose M, Goldstine JV, Gatti RA. Intrinsic mitochondrial dysfunction in ATM-deficient lymphoblastoid cells. Hum Mol Genet. 2007;16(18): 2154-2164. (Pubitemid 47354898)
    • (2007) Human Molecular Genetics , vol.16 , Issue.18 , pp. 2154-2164
    • Ambrose, M.1    Goldstine, J.V.2    Gatti, R.A.3
  • 22
    • 0022380768 scopus 로고
    • The c-myc oncogene driven by immunoglobulin enhancers induces lymphoid malignancy in transgenic mice
    • DOI 10.1038/318533a0
    • Adams JM, Harris AW, Pinkert CA, et al. The cmyc oncogene driven by immunoglobulin enhancers induces lymphoid malignancy in transgenic mice. Nature. 1985;318(6046):533-538. (Pubitemid 16173038)
    • (1985) Nature , vol.318 , Issue.6046 , pp. 533-538
    • Adams, J.M.1    Harris, A.W.2    Pinkert, C.A.3
  • 23
    • 54749148734 scopus 로고    scopus 로고
    • Transient inhibition ofATM kinase is sufficient to enhance cellular sensitivity to ionizing radiation
    • Rainey MD, Charlton ME, Stanton RV, Kastan MB. Transient inhibition ofATM kinase is sufficient to enhance cellular sensitivity to ionizing radiation. Cancer Res. 2008;68(18):7466-7474.
    • (2008) Cancer Res , vol.68 , Issue.18 , pp. 7466-7474
    • Rainey, M.D.1    Charlton, M.E.2    Stanton, R.V.3    Kastan, M.B.4
  • 24
    • 2942687831 scopus 로고    scopus 로고
    • Phosphorylation of SMC1 is a critical downstream event in the ATM-NBS1-BRCA1 pathway
    • DOI 10.1101/gad.1200304
    • Kitagawa R, Bakkenist CJ, McKinnon PJ, Kastan MB. Phosphorylation of SMC1 is a critical downstream event in the ATM-NBS1-BRCA1 pathway. Genes Dev. 2004;18(12):1423-1438. (Pubitemid 38780629)
    • (2004) Genes and Development , vol.18 , Issue.12 , pp. 1423-1438
    • Kitagawa, R.1    Bakkenist, C.J.2    McKinnon, P.J.3    Kastan, M.B.4
  • 25
    • 38149141767 scopus 로고    scopus 로고
    • Targeting lysosomal degradation induces p53-dependent cell death and prevents cancer in mouse models of lymphomagenesis
    • Maclean KH, Dorsey FC, Cleveland JL, Kastan MB. Targeting lysosomal degradation induces p53-dependent cell death and prevents cancer in mouse models of lymphomagenesis. J Clin Invest. 2008; 118(1):79-88.
    • (2008) J Clin Invest , vol.118 , Issue.1 , pp. 79-88
    • Maclean, K.H.1    Dorsey, F.C.2    Cleveland, J.L.3    Kastan, M.B.4
  • 26
    • 40649083487 scopus 로고    scopus 로고
    • Advances in measuring cellular bioenergetics using extracellular flux
    • Ferrick DA, Neilson A, Beeson C. Advances in measuring cellular bioenergetics using extracellular flux. Drug Discov Today. 2008;13(5-6):268-274.
    • (2008) Drug Discov Today , vol.13 , Issue.5-6 , pp. 268-274
    • Ferrick, D.A.1    Neilson, A.2    Beeson, C.3
  • 27
    • 79953210362 scopus 로고    scopus 로고
    • Regulation of PGC-1alpha, a nodal regulator of mitochondrial biogenesis
    • Fernandez-Marcos PJ, Auwerx J. Regulation of PGC-1alpha, a nodal regulator of mitochondrial biogenesis. Am J Clin Nutr. 2011;93(4):884S-890S.
    • (2011) Am J Clin Nutr , vol.93 , Issue.4
    • Fernandez-Marcos, P.J.1    Auwerx, J.2
  • 29
    • 43949125194 scopus 로고    scopus 로고
    • Mitochondrial autophagy: Life and breath of the cell
    • Semenza GL. Mitochondrial autophagy: life and breath of the cell. Autophagy. 2008;4(4):534-536. (Pubitemid 351705156)
    • (2008) Autophagy , vol.4 , Issue.4 , pp. 534-536
    • Semenza, G.L.1
  • 30
    • 77950495123 scopus 로고    scopus 로고
    • Physiological significance of selective degradation of p62 by autophagy
    • Komatsu M, Ichimura Y. Physiological significance of selective degradation of p62 by autophagy. FEBS Lett. 2010;584(7):1374-1378.
    • (2010) FEBS Lett , vol.584 , Issue.7 , pp. 1374-1378
    • Komatsu, M.1    Ichimura, Y.2
  • 31
    • 75749122303 scopus 로고    scopus 로고
    • Methods in mammalian autophagy research
    • Mizushima N, Yoshimori T, Levine B. Methods in mammalian autophagy research. Cell. 2010; 140(3):313-326.
    • (2010) Cell , vol.140 , Issue.3 , pp. 313-326
    • Mizushima, N.1    Yoshimori, T.2    Levine, B.3
  • 32
    • 24044506249 scopus 로고    scopus 로고
    • Roles of Drosophila DJ-1 in survival of dopaminergic neurons and oxidative stress
    • DOI 10.1016/j.cub.2005.07.036, PII S0960982205007918
    • Menzies FM, Yenisetti SC, Min KT. Roles of Drosophila DJ-1 in survival of dopaminergic neurons and oxidative stress. Curr Biol. 2005;15(17): 1578-1582. (Pubitemid 41219598)
    • (2005) Current Biology , vol.15 , Issue.17 , pp. 1578-1582
    • Menzies, F.M.1    Yenisetti, S.C.2    Min, K.-T.3
  • 33
    • 1642527499 scopus 로고    scopus 로고
    • DJ-1 has a role in antioxidative stress to prevent cell death
    • DOI 10.1038/sj.embor.7400074
    • Taira T, Saito Y, Niki T, Iguchi-Ariga SM, Takahashi K, Ariga H. DJ-1 has a role in antioxidative stress to prevent cell death. EMBO Rep. 2004;5(2):213-218. (Pubitemid 38401204)
    • (2004) EMBO Reports , vol.5 , Issue.2 , pp. 213-218
    • Taira, T.1    Saito, Y.2    Niki, T.3    Iguchi-Ariga, S.M.M.4    Takahashi, K.5    Ariga, H.6
  • 34
    • 0038309329 scopus 로고    scopus 로고
    • The molecular mechanism of autophagy
    • Wang CW, Klionsky DJ. The molecular mechanism of autophagy. Mol Med. 2003;9(3-4):65-76. (Pubitemid 36819962)
    • (2003) Molecular Medicine , vol.9 , Issue.3-4 , pp. 65-76
    • Wang, C.-W.1    Klionsky, D.J.2
  • 36
    • 79955057180 scopus 로고    scopus 로고
    • The Nrf2/ ARE pathway: A promising target to counteract mitochondrial dysfunction in Parkinson's disease
    • Tufekci KU, Civi BE, Genc S, Genc K. The Nrf2/ ARE pathway: a promising target to counteract mitochondrial dysfunction in Parkinson's disease. Parkinsons Dis. 2011;2011:314082.
    • (2011) Parkinsons Dis , vol.2011 , pp. 314082
    • Tufekci, K.U.1    Civi, B.E.2    Genc, S.3    Genc, K.4
  • 40
    • 78649704325 scopus 로고    scopus 로고
    • Autophagy and metabolism
    • Rabinowitz JD, White E. Autophagy and metabolism. Science. 2010;330(6009):1344-1348.
    • (2010) Science , vol.330 , Issue.6009 , pp. 1344-1348
    • Rabinowitz, J.D.1    White, E.2
  • 41
    • 79551580561 scopus 로고    scopus 로고
    • ATM activates the pentose phosphate pathway promoting anti-oxidant defence and DNA repair
    • Cosentino C, Grieco D, Costanzo V. ATM activates the pentose phosphate pathway promoting anti-oxidant defence and DNA repair. EMBO J. 2011;30(3):546-555.
    • (2011) EMBO J , vol.30 , Issue.3 , pp. 546-555
    • Cosentino, C.1    Grieco, D.2    Costanzo, V.3
  • 42
    • 0033621392 scopus 로고    scopus 로고
    • Substrate specificities and identification of putative substrates of ATM kinase family members
    • DOI 10.1074/jbc.274.53.37538
    • Kim S-T, Lim D-S, Canman CE, Kastan MB. Substrate specificities and identification of putative substrates of ATM kinase family members. J Biol Chem. 1999;274:37538-37543. (Pubitemid 30026807)
    • (1999) Journal of Biological Chemistry , vol.274 , Issue.53 , pp. 37538-37543
    • Kim, S.-T.1    Lim, D.-S.2    Canman, C.E.3    Kastan, M.B.4
  • 45
    • 65649118917 scopus 로고    scopus 로고
    • Parkin, PINK1, and DJ-1 form a ubiquitin E3 ligase complex promoting unfolded protein degradation
    • Xiong H, Wang D, Chen L, et al. Parkin, PINK1, and DJ-1 form a ubiquitin E3 ligase complex promoting unfolded protein degradation. J Clin Invest. 2009;119(3):650-660.
    • (2009) J Clin Invest , vol.119 , Issue.3 , pp. 650-660
    • Xiong, H.1    Wang, D.2    Chen, L.3
  • 46
    • 79956323688 scopus 로고    scopus 로고
    • DJ-1 acts in parallel to the PINK1/parkin pathway to control mitochondrial function and autophagy
    • Thomas KJ, McCoy MK, Blackinton J, et al. DJ-1 acts in parallel to the PINK1/parkin pathway to control mitochondrial function and autophagy. Hum Mol Genet. 2011;20(1):40-50.
    • (2011) Hum Mol Genet , vol.20 , Issue.1 , pp. 40-50
    • Thomas, K.J.1    McCoy, M.K.2    Blackinton, J.3
  • 48
    • 37349004102 scopus 로고    scopus 로고
    • Parkinson's disease
    • Thomas B, Beal MF. Parkinson's disease. Hum Mol Genet. 2007;16(spec no. 2):R183-R194.
    • (2007) Hum Mol Genet , vol.16 , Issue.SPEC NO. 2
    • Thomas, B.1    Beal, M.F.2


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