-
1
-
-
33747195353
-
Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors
-
Takahashi K, Yamanaka S (2006) Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors. Cell 126: 663-676.
-
(2006)
Cell
, vol.126
, pp. 663-676
-
-
Takahashi, K.1
Yamanaka, S.2
-
2
-
-
36248966518
-
Induction of pluripotent stem cells from adult human fibroblasts by defined factors
-
Takahashi K, Tanabe K, Ohnuki M, Narita M, Ichisaka T, et al. (2007) Induction of pluripotent stem cells from adult human fibroblasts by defined factors. Cell 131: 861-872.
-
(2007)
Cell
, vol.131
, pp. 861-872
-
-
Takahashi, K.1
Tanabe, K.2
Ohnuki, M.3
Narita, M.4
Ichisaka, T.5
-
3
-
-
36749043230
-
Induced pluripotent stem cell lines derived from human somatic cells
-
Yu J, Vodyanik MA, Smuga-Otto K, Antosiewicz-Bourget J, Frane JL, et al. (2007) Induced pluripotent stem cell lines derived from human somatic cells. Science 318: 1917-1920.
-
(2007)
Science
, vol.318
, pp. 1917-1920
-
-
Yu, J.1
Vodyanik, M.A.2
Smuga-Otto, K.3
Antosiewicz-Bourget, J.4
Frane, J.L.5
-
4
-
-
0038143611
-
Functional expression cloning of Nanog, a pluripotency sustaining factor in embryonic stem cells
-
Chambers I, Colby D, Robertson M, Nichols J, Lee S, et al. (2003) Functional expression cloning of Nanog, a pluripotency sustaining factor in embryonic stem cells. Cell 113: 643-655.
-
(2003)
Cell
, vol.113
, pp. 643-655
-
-
Chambers, I.1
Colby, D.2
Robertson, M.3
Nichols, J.4
Lee, S.5
-
5
-
-
2142821474
-
Identification, cloning and expression analysis of the pluripotency promoting Nanog genes in mouse and human
-
Hart AH, Hartley L, Ibrahim M, Robb L (2004) Identification, cloning and expression analysis of the pluripotency promoting Nanog genes in mouse and human. Dev Dyn 230: 187-198.
-
(2004)
Dev Dyn
, vol.230
, pp. 187-198
-
-
Hart, A.H.1
Hartley, L.2
Ibrahim, M.3
Robb, L.4
-
6
-
-
0037806031
-
The homeoprotein Nanog is required for maintenance of pluripotency in mouse epiblast and ES cells
-
Mitsui K, Tokuzawa Y, Itoh H, Segawa K, Murakami M, et al. (2003) The homeoprotein Nanog is required for maintenance of pluripotency in mouse epiblast and ES cells. Cell 113: 631-642.
-
(2003)
Cell
, vol.113
, pp. 631-642
-
-
Mitsui, K.1
Tokuzawa, Y.2
Itoh, H.3
Segawa, K.4
Murakami, M.5
-
7
-
-
0032582513
-
Formation of pluripotent stem cells in the mammalian embryo depends on the POU transcription factor Oct4
-
Nichols J, Zevnik B, Anastassiadis K, Niwa H, Klewe-Nebenius D, et al. (1998) Formation of pluripotent stem cells in the mammalian embryo depends on the POU transcription factor Oct4. Cell 95: 379-391.
-
(1998)
Cell
, vol.95
, pp. 379-391
-
-
Nichols, J.1
Zevnik, B.2
Anastassiadis, K.3
Niwa, H.4
Klewe-Nebenius, D.5
-
8
-
-
25144525014
-
Core transcriptional regulatory circuitry in human embryonic stem cells
-
Boyer LA, Lee TI, Cole MF, Johnstone SE, Levine SS, et al. (2005) Core transcriptional regulatory circuitry in human embryonic stem cells. Cell 122: 947-956.
-
(2005)
Cell
, vol.122
, pp. 947-956
-
-
Boyer, L.A.1
Lee, T.I.2
Cole, M.F.3
Johnstone, S.E.4
Levine, S.S.5
-
9
-
-
64249157351
-
Epigenetic reprogramming and induced pluripotency
-
Hochedlinger K, Plath K (2009) Epigenetic reprogramming and induced pluripotency. Development 136: 509-523.
-
(2009)
Development
, vol.136
, pp. 509-523
-
-
Hochedlinger, K.1
Plath, K.2
-
10
-
-
34249880066
-
Generation of germline-competent induced pluripotent stem cells
-
Okita K, Ichisaka T, Yamanaka S (2007) Generation of germline-competent induced pluripotent stem cells. Nature 448: 313-317.
-
(2007)
Nature
, vol.448
, pp. 313-317
-
-
Okita, K.1
Ichisaka, T.2
Yamanaka, S.3
-
11
-
-
69349103956
-
The Ink4/Arf locus is a barrier for iPS cell reprogramming
-
Li H, Collado M, Villasante A, Strati K, Ortega S, et al. (2009) The Ink4/Arf locus is a barrier for iPS cell reprogramming. Nature 460: 1136-1139.
-
(2009)
Nature
, vol.460
, pp. 1136-1139
-
-
Li, H.1
Collado, M.2
Villasante, A.3
Strati, K.4
Ortega, S.5
-
12
-
-
69349100455
-
Linking the p53 tumour suppressor pathway to somatic cell reprogramming
-
Kawamura T, Suzuki J, Wang YV, Menendez S, Morera LB, et al. (2009) Linking the p53 tumour suppressor pathway to somatic cell reprogramming. Nature 460: 1140-1144.
-
(2009)
Nature
, vol.460
, pp. 1140-1144
-
-
Kawamura, T.1
Suzuki, J.2
Wang, Y.V.3
Menendez, S.4
Morera, L.B.5
-
13
-
-
69349100179
-
Suppression of induced pluripotent stem cell generation by the p53-p21 pathway
-
Hong H, Takahashi K, Ichisaka T, Aoi T, Kanagawa O, et al. (2009) Suppression of induced pluripotent stem cell generation by the p53-p21 pathway. Nature 460: 1132-1135.
-
(2009)
Nature
, vol.460
, pp. 1132-1135
-
-
Hong, H.1
Takahashi, K.2
Ichisaka, T.3
Aoi, T.4
Kanagawa, O.5
-
14
-
-
69349098273
-
Immortalization eliminates a roadblock during cellular reprogramming into iPS cells
-
Utikal J, Polo JM, Stadtfeld M, Maherali N, Kulalert W, et al. (2009) Immortalization eliminates a roadblock during cellular reprogramming into iPS cells. Nature 460: 1145-1148.
-
(2009)
Nature
, vol.460
, pp. 1145-1148
-
-
Utikal, J.1
Polo, J.M.2
Stadtfeld, M.3
Maherali, N.4
Kulalert, W.5
-
15
-
-
70349964673
-
Genome integrity: Linking pluripotency and tumorgenicity
-
Deng W, Xu Y (2009) Genome integrity: linking pluripotency and tumorgenicity. Trends Genet 25: 425-427.
-
(2009)
Trends Genet
, vol.25
, pp. 425-427
-
-
Deng, W.1
Xu, Y.2
-
16
-
-
0032491416
-
Embryonic stem cell lines derived from human blastocysts
-
Thomson JA, Itskovitz-Eldor J, Shapiro SS, Waknitz MA, Swiergiel JJ, et al. (1998) Embryonic stem cell lines derived from human blastocysts. Science 282: 1145-1147.
-
(1998)
Science
, vol.282
, pp. 1145-1147
-
-
Thomson, J.A.1
Itskovitz-Eldor, J.2
Shapiro, S.S.3
Waknitz, M.A.4
Swiergiel, J.J.5
-
17
-
-
33750524413
-
Self-renewal of human embryonic stem cells is supported by a shortened G1 cell cycle phase
-
Becker KA, Ghule PN, Therrien JA, Lian JB, Stein JL, et al. (2006) Self-renewal of human embryonic stem cells is supported by a shortened G1 cell cycle phase. J Cell Physiol 209: 883-893.
-
(2006)
J Cell Physiol
, vol.209
, pp. 883-893
-
-
Becker, K.A.1
Ghule, P.N.2
Therrien, J.A.3
Lian, J.B.4
Stein, J.L.5
-
18
-
-
69249126660
-
Ionizing radiation induces ataxia telangiectasia mutated-dependent checkpoint signaling and G(2) but not G(1) cell cycle arrest in pluripotent human embryonic stem cells
-
Momcilovic O, Choi S, Varum S, Bakkenist C, Schatten G, et al. (2009) Ionizing radiation induces ataxia telangiectasia mutated-dependent checkpoint signaling and G(2) but not G(1) cell cycle arrest in pluripotent human embryonic stem cells. Stem Cells 27: 1822-1835.
-
(2009)
Stem Cells
, vol.27
, pp. 1822-1835
-
-
Momcilovic, O.1
Choi, S.2
Varum, S.3
Bakkenist, C.4
Schatten, G.5
-
19
-
-
0032576768
-
ES cells do not activate p53-dependent stress responses and undergo p53- independent apoptosis in response to DNA damage
-
Aladjem MI, Spike BT, Rodewald LW, Hope TJ, Klemm M, et al. (1998) ES cells do not activate p53-dependent stress responses and undergo p53- independent apoptosis in response to DNA damage. Curr Biol 8: 145-155.
-
(1998)
Curr Biol
, vol.8
, pp. 145-155
-
-
Aladjem, M.I.1
Spike, B.T.2
Rodewald, L.W.3
Hope, T.J.4
Klemm, M.5
-
20
-
-
0035449355
-
Cell cycle checkpoint signaling through the ATM and ATR kinases
-
Abraham RT (2001) Cell cycle checkpoint signaling through the ATM and ATR kinases. Genes Dev 15: 2177-2196.
-
(2001)
Genes Dev
, vol.15
, pp. 2177-2196
-
-
Abraham, R.T.1
-
21
-
-
0037472924
-
DNA damage activates ATM through intermolecular autophosphorylation and dimer dissociation
-
Bakkenist CJ, Kastan MB (2003) DNA damage activates ATM through intermolecular autophosphorylation and dimer dissociation. Nature 421: 499-506.
-
(2003)
Nature
, vol.421
, pp. 499-506
-
-
Bakkenist, C.J.1
Kastan, M.B.2
-
23
-
-
0033555260
-
A role for ATR in the DNA damage-induced phosphorylation of p53
-
Tibbetts RS, Brumbaugh KM, Williams JM, Sarkaria JN, Cliby WA, et al. (1999) A role for ATR in the DNA damage-induced phosphorylation of p53. Genes Dev 13: 152-157.
-
(1999)
Genes Dev
, vol.13
, pp. 152-157
-
-
Tibbetts, R.S.1
Brumbaugh, K.M.2
Williams, J.M.3
Sarkaria, J.N.4
Cliby, W.A.5
-
24
-
-
5144231886
-
Restoration of an absent G1 arrest and protection from apoptosis in embryonic stem cells after ionizing radiation
-
Hong Y, Stambrook PJ (2004) Restoration of an absent G1 arrest and protection from apoptosis in embryonic stem cells after ionizing radiation. Proc Natl Acad Sci U S A 101: 14443-14448.
-
(2004)
Proc Natl Acad Sci U S A
, vol.101
, pp. 14443-14448
-
-
Hong, Y.1
Stambrook, P.J.2
-
25
-
-
33744975288
-
Cell cycle features of primate embryonic stem cells
-
Fluckiger AC, Marcy G, Marchand M, Negre D, Cosset FL, et al. (2006) Cell cycle features of primate embryonic stem cells. Stem Cells 24: 547-556.
-
(2006)
Stem Cells
, vol.24
, pp. 547-556
-
-
Fluckiger, A.C.1
Marcy, G.2
Marchand, M.3
Negre, D.4
Cosset, F.L.5
-
26
-
-
64349094838
-
Explanation for excessive DNA single-strand breaks and endogenous repair foci in pluripotent mouse embryonic stem cells
-
Banath JP, Banuelos CA, Klokov D, MacPhail SM, Lansdorp PM, et al. (2009) Explanation for excessive DNA single-strand breaks and endogenous repair foci in pluripotent mouse embryonic stem cells. Exp Cell Res 315: 1505-1520.
-
(2009)
Exp Cell Res
, vol.315
, pp. 1505-1520
-
-
Banath, J.P.1
Banuelos, C.A.2
Klokov, D.3
McPhail, S.M.4
Lansdorp, P.M.5
-
27
-
-
29744447772
-
Hyperdynamic plasticity of chromatin proteins in pluripotent embryonic stem cells
-
Meshorer E, Yellajoshula D, George E, Scambler PJ, Brown DT, et al. (2006) Hyperdynamic plasticity of chromatin proteins in pluripotent embryonic stem cells. Dev Cell 10: 105-116.
-
(2006)
Dev Cell
, vol.10
, pp. 105-116
-
-
Meshorer, E.1
Yellajoshula, D.2
George, E.3
Scambler, P.J.4
Brown, D.T.5
-
28
-
-
55049090534
-
Human Embryonic Stem Cells have Enhanced Repair of Multiple Forms of DNA Damage
-
Maynard S, Swistikowa AM, Lee JW, Liu Y, Liu ST, et al. (2008) Human Embryonic Stem Cells have Enhanced Repair of Multiple Forms of DNA Damage. Stem Cells.
-
(2008)
Stem Cells
-
-
Maynard, S.1
Swistikowa, A.M.2
Lee, J.W.3
Liu, Y.4
Liu, S.T.5
-
29
-
-
78049381196
-
Mouse embryonic stem cells but not somatic cells predominantly use homologous recombination to repair double strand DNA breaks
-
Tichy ED, Pillai R, Deng L, Liang L, Tischfield JA, et al. Mouse embryonic stem cells but not somatic cells predominantly use homologous recombination to repair double strand DNA breaks. Stem Cells Dev.
-
Stem Cells Dev
-
-
Tichy, E.D.1
Pillai, R.2
Deng, L.3
Liang, L.4
Tischfield, J.A.5
-
30
-
-
43049176659
-
DNA repair in murine embryonic stem cells and differentiated cells
-
Tichy ED, Stambrook PJ (2008) DNA repair in murine embryonic stem cells and differentiated cells. Exp Cell Res 314: 1929-1936.
-
(2008)
Exp Cell Res
, vol.314
, pp. 1929-1936
-
-
Tichy, E.D.1
Stambrook, P.J.2
-
31
-
-
0032861343
-
Megabase chromatin domains involved in DNA double-strand breaks in vivo
-
Rogakou EP, Boon C, Redon C, Bonner WM (1999) Megabase chromatin domains involved in DNA double-strand breaks in vivo. J Cell Biol 146: 905-916.
-
(1999)
J Cell Biol
, vol.146
, pp. 905-916
-
-
Rogakou, E.P.1
Boon, C.2
Redon, C.3
Bonner, W.M.4
-
32
-
-
0032489520
-
DNA doublestranded breaks induce histone H2AX phosphorylation on serine 139
-
Rogakou EP, Pilch DR, Orr AH, Ivanova VS, Bonner WM (1998) DNA doublestranded breaks induce histone H2AX phosphorylation on serine 139. J Biol Chem 273: 5858-5868.
-
(1998)
J Biol Chem
, vol.273
, pp. 5858-5868
-
-
Rogakou, E.P.1
Pilch, D.R.2
Orr, A.H.3
Ivanova, V.S.4
Bonner, W.M.5
-
33
-
-
78951484462
-
Homologous Recombination conserves DNA sequence integrity throughout the cell cycle in embryonic stem cells
-
Serrano L, Liang L, Chang Y, Deng L, Maulion C, et al. Homologous Recombination conserves DNA sequence integrity throughout the cell cycle in embryonic stem cells. Stem Cells Dev.
-
Stem Cells Dev
-
-
Serrano, L.1
Liang, L.2
Chang, Y.3
Deng, L.4
Maulion, C.5
-
34
-
-
48149108735
-
Mouse but not human embryonic stem cells are deficient in rejoining of ionizing radiation-induced DNA double-strand breaks
-
Banuelos CA, Banath JP, Macphail SH, Zhao J, Eaves CA, et al. (2008) Mouse but not human embryonic stem cells are deficient in rejoining of ionizing radiation-induced DNA double-strand breaks. DNA Repair (Amst) 7: 1471-1483.
-
(2008)
DNA Repair (Amst)
, vol.7
, pp. 1471-1483
-
-
Banuelos, C.A.1
Banath, J.P.2
Macphail, S.H.3
Zhao, J.4
Eaves, C.A.5
-
35
-
-
0028897304
-
DNA-dependent protein kinase activity is absent in xrs-6 cells: Implications for site-specific recombination and DNA double-strand break repair
-
Finnie NJ, Gottlieb TM, Blunt T, Jeggo PA, Jackson SP (1995) DNA-dependent protein kinase activity is absent in xrs-6 cells: implications for site-specific recombination and DNA double-strand break repair. Proc Natl Acad Sci U S A 92: 320-324.
-
(1995)
Proc Natl Acad Sci U S A
, vol.92
, pp. 320-324
-
-
Finnie, N.J.1
Gottlieb, T.M.2
Blunt, T.3
Jeggo, P.A.4
Jackson, S.P.5
-
38
-
-
65249149666
-
Induced pluripotent stem cell generation using a single lentiviral stem cell cassette
-
Sommer CA, Stadtfeld M, Murphy GJ, Hochedlinger K, Kotton DN, et al. (2009) Induced pluripotent stem cell generation using a single lentiviral stem cell cassette. Stem Cells 27: 543-549.
-
(2009)
Stem Cells
, vol.27
, pp. 543-549
-
-
Sommer, C.A.1
Stadtfeld, M.2
Murphy, G.J.3
Hochedlinger, K.4
Kotton, D.N.5
-
39
-
-
77956707391
-
The involvement of human RECQL4 in DNA double-strand break repair
-
Singh DK, Karmakar P, Aamann M, Schurman SH, May A, et al. The involvement of human RECQL4 in DNA double-strand break repair. Aging Cell.
-
Aging Cell
-
-
Singh, D.K.1
Karmakar, P.2
Aamann, M.3
Schurman, S.H.4
May, A.5
|