Overexpression of DNA ligase III in mitochondria protects cells against oxidative stress and improves mitochondrial DNA base excision repair

DNA Repair

Volumn 16, Issue 1, 2014, Pages 44-53

  Akbari, Mansour ^a   Keijzers, Guido ^a   Maynard, Scott ^a   Scheibye Knudsen, Morten ^b   Desler, Claus ^a   Hickson, Ian D ^a   Bohr, Vilhelm A ^a,b  

^a UNIVERSITY OF COPENHAGEN   (Denmark)

^b NATIONAL INSTITUTE ON AGING   (United States)

Author keywords

Autophagy; Cell survival; Mitochondrial DNA repair intermediates; Oxidative stress

Indexed keywords

CIRCULAR DNA; DNA LIGASE III; MENADIONE; MITOCHONDRIAL DNA; POLYDEOXYRIBONUCLEOTIDE SYNTHASE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE (UBIQUINONE); ROTENONE; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; AUTOPHAGY; CELL PROTECTION; CELL SURVIVAL; DNA LIGATION; EXCISION REPAIR; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; MITOCHONDRIAL ENERGY TRANSFER; MITOCHONDRION; MOUSE; NONHUMAN; NUCLEIC ACID STRUCTURE, METABOLISM AND FUNCTION; OXIDATIVE STRESS; PRIORITY JOURNAL;

AUTOPHAGY; CELL SURVIVAL; MITOCHONDRIAL DNA REPAIR INTERMEDIATES; OXIDATIVE STRESS;

ANIMALS; AUTOPHAGY; BRAIN; CELL LINE, TUMOR; CELL SURVIVAL; DNA LIGASES; DNA REPAIR; DNA, MITOCHONDRIAL; ELECTRON TRANSPORT COMPLEX I; HELA CELLS; HUMANS; MICE; MITOCHONDRIA; OXIDATIVE STRESS; ROTENONE; VITAMIN K 3;

EID: 84896286702     PISSN: 15687864     EISSN: 15687856     Source Type: Journal    
DOI: 10.1016/j.dnarep.2014.01.015     Document Type: Article

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