Mitochondrial aging and age-related dysfunction of mitochondria

BioMed Research International

Volumn 2014, Issue , 2014, Pages

  Chistiakov, Dimitry A ^a   Sobenin, Igor A ^b,c   Revin, Victor V ^d   Orekhov, Alexander N ^c,e   Bobryshev, Yuri V ^d,f,g  

^a PIROGOV RUSSIAN NATIONAL RESEARCH MEDICAL UNIVERSITY   (Russian Federation)

^b INSTITUTE OF EXPERIMENTAL CARDIOLOGY   (Russian Federation)

^c INSTITUTE OF GENERAL PATHOLOGY AND PATHOPHYSIOLOGY   (Russian Federation)

^d OGAREV MORDOVIA STATE UNIVERSITY   (Russian Federation)

^e Institute for Atherosclerosis Research   (Russian Federation)

^f UNIVERSITY OF NEW SOUTH WALES   (Australia)

^g UNIVERSITY OF WESTERN SYDNEY   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIOXIDANT; MITOCHONDRIAL DNA; REACTIVE OXYGEN METABOLITE;

AGING; APOPTOSIS; ATHEROGENESIS; AUTOPHAGY; BIOGENESIS; CALORIC RESTRICTION; DISORDERS OF MITOCHONDRIAL FUNCTIONS; HUMAN; MITOCHONDRIAL DYNAMICS; MITOCHONDRIAL GENE; MITOCHONDRIAL MEMBRANE; MITOPHAGY; NONHUMAN; OXIDATIVE PHOSPHORYLATION; PHENOTYPE; QUALITY CONTROL; REVIEW; TRAINING; ANIMAL; CELL AGING; GENETICS; METABOLISM; MITOCHONDRION; PATHOLOGY;

AGING; ANIMALS; CELL AGING; DNA, MITOCHONDRIAL; HUMANS; MITOCHONDRIA; MITOCHONDRIAL DYNAMICS; REACTIVE OXYGEN SPECIES;

EID: 84900330082     PISSN: 23146133     EISSN: 23146141     Source Type: Journal    
DOI: 10.1155/2014/238463     Document Type: Review

References (52)

1. Harman D., The biologic clock: the mitochondria? Journal of the American Geriatrics Society 1972 20 4 145 147 2-s2.0-0015319592
2. Edgar D., Trifunovic A., The mtDNA mutator mouse: dissecting mitochondrial involvement in aging. Aging 2009 1 12 1028 1032 2-s2.0-77953630947
3. Doonan R., McElwee J. J., Matthijssens F., Walker G. A., Houthoofd K., Back P., Matscheski A., Vanfleteren J. R., Gems D., Against the oxidative damage theory of aging: superoxide dismutases protect against oxidative stress but have little or no effect on life span in Caenorhabditis elegans. Genes and Development 2008 22 23 3236 3241 2-s2.0-57749095081 10.1101/gad.504808
4. Ding W. X., Yin X. M., Mitophagy: mechanisms, pathophysiological roles, and analysis. Biol Chem 2012 393 547 564
5. Short K. R., Bigelow M. L., Kahl J., Singh R., Coenen-Schimke J., Raghavakaimal S., Nair K. S., Decline in skeletal muscle mitochondrial function with aging in humans. Proceedings of the National Academy of Sciences of the United States of America 2005 102 15 5618 5623 2-s2.0-17244363631 10.1073/pnas.0501559102 (Pubitemid 40530306)
6. Wallace D. C., Mitochondrial DNA mutations in disease and aging. Environmental and Molecular Mutagenesis 2010 51 5 440 450 2-s2.0-77953507107 10.1002/em.20586
7. Alexeyev M. F., LeDoux S. P., Wilson G. L., Mitochondrial DNA and aging. Clinical Science 2004 107 4 355 364 2-s2.0-6344278442 10.1042/CS20040148 (Pubitemid 39389302)
8. Trifunovic A., Hansson A., Wredenberg A., Rovio A. T., Dufour E., Khvorostov I., Spelbrink J. N., Wibom R., Jacobs H. T., Larsson N.-G., Somatic mtDNA mutations cause aging phenotypes without affecting reactive oxygen species production. Proceedings of the National Academy of Sciences of the United States of America 2005 102 50 17993 17998 2-s2.0-29144458899 10.1073/pnas.0508886102 (Pubitemid 41798490)
9. Richter C., Park J.-W., Ames B. N., Normal oxidative damage to mitochondrial and nuclear DNA is extensive. Proceedings of the National Academy of Sciences of the United States of America 1988 85 17 6465 6467 2-s2.0-0023811053
10. Barazzoni R., Short K. R., Nair K. S., Effects of aging on mitochondrial DNA copy number and cytochrome c oxidase gene expression in rat skeletal muscle, liver, and heart. Journal of Biological Chemistry 2000 275 5 3343 3347 2-s2.0-0034602958 10.1074/jbc.275.5.3343 (Pubitemid 30083037)
11. Yang W., Hekimi S., A mitochondrial superoxide signal triggers increased longevity in caenorhabditis elegans. PLoS Biology 2010 8 12 2-s2.0-78650455712 10.1371/journal.pbio.1000556 e1000556
12. Lee S.-J., Hwang A. B., Kenyon C., Inhibition of respiration extends C. elegans life span via reactive oxygen species that increase HIF-1 activity. Current Biology 2010 20 23 2131 2136 2-s2.0-78650177082 10.1016/j.cub.2010.10. 057
13. Sun J., Folk D., Bradley T. J., Tower J., Induced overexpression of mitochondrial Mn-superoxide dismutase extends the life span of adult Drosophila melanogaster. Genetics 2002 161 2 661 672 2-s2.0-0035989388 (Pubitemid 34705407)
14. Schriner S. E., Linford N. J., Martin G. M., Treuting P., Ogburn C. E., Emond M., Coskun P. E., Ladiges W., Wolf N., Van Remmen H., Wallace D. C., Rabinovitch P. S., Medecine: extension of murine life span by overexpression of catalase targeted to mitochondria. Science 2005 308 5730 1909 1911 2-s2.0-21144434217 10.1126/science.1106653 (Pubitemid 40941874)
15. Lebovitz R. M., Zhang H., Vogel H., Cartwright J. Jr., Dionne L., Lu N., Huang S., Matzuk M. M., Neurodegeneration, myocardial injury, and perinatal death in mitochondrial superoxide dismutase-deficient mice. Proceedings of the National Academy of Sciences of the United States of America 1996 93 18 9782 9787 2-s2.0-0029838063 10.1073/pnas.93.18.9782 (Pubitemid 26296686)
16. Migliaccio E., Giorgio M., Pelicci P. G., Apoptosis and aging: role of p66Shc redox protein. Antioxidants and Redox Signaling 2006 8 3-4 600 608 2-s2.0-33646680289 10.1089/ars.2006.8.600 (Pubitemid 43741328)
17. Conley K. E., Jubrias S. A., Esselman P. C., Oxidative capacity and ageing in human muscle. Journal of Physiology 2000 526 1 203 210 2-s2.0-0034234773 (Pubitemid 30456102)
18. Brierley E. J., Johnson M. A., Bowman A., Ford G. A., Subhan F., Reed J. W., James O. F. W., Turnbull D. M., Mitochondrial function in muscle from elderly athletes. Annals of Neurology 1997 41 1 114 116 2-s2.0-0031025165 10.1002/ana.410410120 (Pubitemid 27057102)
19. Larsen R. G., Callahan D. M., Foulis S. A., Kent-Braun J. A., Age-related changes in oxidative capacity differ between locomotory muscles and are associated with physical activity behavior. Applied Physiology, Nutrition and Metabolism 2012 37 1 88 99 2-s2.0-84856569690 10.1139/H11-135
20. Palmer C. S., Osellame L. D., Stojanovski D., Ryan M. T., The regulation of mitochondrial morphology: intricate mechanisms and dynamic machinery. Cellular Signalling 2011 23 10 1534 1545 2-s2.0-79960729178 10.1016/j.cellsig. 2011.05.021
21. Crane J. D., Devries M. C., Safdar A., Hamadeh M. J., Tarnopolsky M. A., The effect of aging on human skeletal muscle mitochondrial and intramyocellular lipid ultrastructure. The Journals of Gerontology Series A 2010 65 2 119 128 2-s2.0-75649142161 10.1093/gerona/glp179
22. Wenz T., Rossi S. G., Rotundo R. L., Spiegelman B. M., Moraes C. T., Increased muscle PGC-1 α expression protects from sarcopenia and metabolic disease during aging. Proceedings of the National Academy of Sciences of the United States of America 2009 106 48 20405 20410 2-s2.0-73949099327 10.1073/pnas.0911570106
23. Wenz T., Mitochondria and PGC-1 α in aging and age-associated diseases. Journal of Aging Research 2011 2011 12 10.4061/2011/810619 810619
24. Cavallini G., Donati A., Taddei M., Bergamini E., Evidence for selective mitochondrial autophagy and failure in aging. Autophagy 2007 3 1 26 27 2-s2.0-33846187292 (Pubitemid 46100706)
25. Masiero E., Sandri M., Autophagy inhibition induces atrophy and myopathy in adult skeletal muscles. Autophagy 2010 6 2 307 309 2-s2.0-77953531909 10.4161/auto.6.2.11137
26. Jeong S.-Y., Seol D.-W., The role of mitochondria in apoptosis. Journal of Biochemistry and Molecular Biology 2008 41 1 11 22 2-s2.0-39049149816 (Pubitemid 351235868)
27. Marzetti E., Leeuwenburgh C., Skeletal muscle apoptosis, sarcopenia and frailty at old age. Experimental Gerontology 2006 41 12 1234 1238 2-s2.0-33845209693 10.1016/j.exger.2006.08.011 (Pubitemid 44848392)
28. Leeuwenburgh C., Gurley C. M., Strotman B. A., Dupont-Versteegden E. E., Age-related differences in apoptosis with disuse atrophy in soleus muscle. American Journal of Physiology 2005 288 5 R1288 R1296 2-s2.0-17844390108 10.1152/ajpregu.00576.2004 (Pubitemid 40593713)
29. Park S. Y., Kim H. Y., Lee J. H., Yoon K. H., Chang M. S., Park S. K., The age-dependent induction of apoptosis-inducing factor (AIF) in the human semitendinosus skeletal muscle. Cellular and Molecular Biology Letters 2010 15 1 1 12 2-s2.0-76149122471 10.2478/s11658-009-0030-4
30. Whitman S. A., Wacker M. J., Richmond S. R., Godard M. P., Contributions of the ubiquitin-proteasome pathway and apoptosis to human skeletal muscle wasting with age. Pflugers Archiv European Journal of Physiology 2005 450 6 437 446 2-s2.0-25644432770 10.1007/s00424-005-1473-8 (Pubitemid 41380702)
31. Bolton E., Rajkumar C., The ageing cardiovascular system. Reviews in Clinical Gerontology 2011 21 2 99 109 2-s2.0-80052210886 10.1017/ S0959259810000389
32. Wang J. C., Bennett M., Aging and atherosclerosis: mechanisms, functional consequences, and potential therapeutics for cellular senescence. Circulation Research 2012 111 245 259
33. Chistiakov D. A., Sobenin I. A., Bobryshev Y. V., Orekhov A. N., Mitochondrial dysfunction and mitochondrial DNA mutations in atherosclerotic complications in diabetes. World Journal of Cardiology 2012 4 148 156
34. Sobenin I. A., Chistiakov D. A., Bobryshev Y. V., Postnov A. Y., Orekhov A. N., Mitochondrial mutations in atherosclerosis: new solutions in research and possible clinical applications. Current Pharmaceutical Design 2013 19 5942 5953
35. Craigen W. J., Mitochondrial DNA mutations: an overview of clinical and molecular aspects. Methods in Molecular Biology 2012 837 3 15 2-s2.0-84856331995 10.1007/978-1-61779-504-6-1
36. Nicholls T. J., Rorbach J., Minczuk M., Mitochondria: mitochondrial RNA metabolism and human disease. The International Journal of Biochemistry & Cell Biology 2013 45 845 849
37. Sobenin I. A., Sazonova M. A., Postnov A. Y., Salonen J. T., Bobryshev Y. V., Orekhov A. N., Association of mitochondrial genetic variation with carotid atherosclerosis. PLoS ONE 2013 8 e68070
38. Sobenin I. A., Sazonova M. A., Postnov A. Y., Bobryshev Y. V., Orekhov A. N., Changes of mitochondria in atherosclerosis: possible determinant in the pathogenesis of the disease. Atherosclerosis 2013 227 283 288
39. Osiewacz H. D., Bernhardt D., Mitochondrial quality control: impact on aging and life span-a mini-review. Gerontology 2013 59 413 420
40. Adam C., Picard M., Dequard-Chablat M., Sellem C. H., Denmat S. H., Contamine V., Biological roles of the Podospora anserina mitochondrial Lon protease and the importance of its N-domain. PLoS ONE 2012 7 e38138
41. Ngo J. K., Pomatto L. C. D., Davies: K. J. A., Upregulation of the mitochondrial Lon Protease allows adaptation to acute oxidative stress but dysregulation is associated with chronic stress, disease, and aging. Redox Biology 2013 1 258 264
42. Taylor E. B., Rutter J., Mitochondrial quality control by the ubiquitin-proteasome system. Biochemical Society Transactions 2011 39 5 1509 1513 2-s2.0-80053352130 10.1042/BST0391509
43. Löw P., The role of ubiquitin-proteasome system in ageing. General and Comparative Endocrinology 2011 172 1 39 43 2-s2.0-79955737369 10.1016/j.ygcen.2011.02.005
44. Altun M., Besche H. C., Overkleeft H. S., Piccirillo R., Edelmann M. J., Kessler B. M., Goldberg A. L., Ulfhake B., Muscle wasting in aged, sarcopenic rats is associated with enhanced activity of the ubiquitin proteasome pathway. Journal of Biological Chemistry 2010 285 51 39597 39608 2-s2.0-78650046347 10.1074/jbc.M110.129718
45. Pan Y., Nishida Y., Wang M., Verdin E., Metabolic regulation, mitochondria and the life-prolonging effect of rapamycin: a mini-review. Gerontology 2012 58 524 530
46. Peterson C. M., Johannsen D. L., Ravussin E., Skeletal muscle mitochondria and aging: a review. Journal of Aging Research 2012 2012 20 10.1155/2012/194821 194821
47. Civitarese A. E., Carling S., Heilbronn L. K., Hulver M. H., Ukropcova B., Deutsch W. A., Smith S. R., Ravussin E., Calorie restriction increases muscle mitochondrial biogenesis in healthy humans. PLoS Medicine 2007 4 3 485 494 2-s2.0-33947710793 10.1371/journal.pmed.0040076 (Pubitemid 46495316)
48. Steiner J. L., Murphy E. A., McClellan J. L., Carmichael M. D., Davis J. M., Exercise training increases mitochondrial biogenesis in the brain. Journal of Applied Physiology 2011 111 4 1066 1071 2-s2.0-80054691291 10.1152/japplphysiol.00343.2011
49. Short K. R., Vittone J. L., Bigelow M. L., Proctor D. N., Rizza R. A., Coenen-Schimke J. M., Nair K. S., Impact of aerobic exercise training on age-related changes in insulin sensitivity and muscle oxidative capacity. Diabetes 2003 52 8 1888 1896 2-s2.0-0042266366 10.2337/diabetes.52.8.1888 (Pubitemid 36919778)
50. Ghosh S., Lertwattanarak R., Lefort N., Molina-Carrion M., Joya-Galeana J., Bowen B. P., Garduno-Garcia J. D. J., Abdul-Ghani M., Richardson A., DeFronzo R. A., Mandarino L., Van Remmen H., Musi N., Reduction in reactive oxygen species production by mitochondria from elderly subjects with normal and impaired glucose tolerance. Diabetes 2011 60 8 2051 2060 2-s2.0-80052830501 10.2337/db11-0121
51. Psilander N., Frank P., Flockhart M., Sahlin K., Exercise with low glycogen increases PGC-1 α gene expression in human skeletal muscle. European Journal of Applied Physiology 2013 113 951 963
52. Lefevre M., Redman L. M., Heilbronn L. K., Smith J. V., Martin C. K., Rood J. C., Greenway F. L., Williamson D. A., Smith S. R., Ravussin E., Caloric restriction alone and with exercise improves CVD risk in healthy non-obese individuals. Atherosclerosis 2009 203 1 206 213 2-s2.0-60649110218 10.1016/j.atherosclerosis.2008.05.036