Patterns of age-specific means and genetic variances of mortality rates predicted by the mutation-accumulation theory of ageing

Journal of Theoretical Biology

Volumn 210, Issue 1, 2001, Pages 47-65

  Charlesworth, Brian ^a  

^a UNIVERSITY OF EDINBURGH   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

AGING; ARTICLE; DROSOPHILA; GENETIC VARIABILITY; HUMAN; LIFE CYCLE; MORTALITY; MUTATION; NONHUMAN; PREDICTION; PRIORITY JOURNAL; QUANTITATIVE GENETICS; THEORY;

EID: 0035820667     PISSN: 00225193     EISSN: None     Source Type: Journal    
DOI: 10.1006/jtbi.2001.2296     Document Type: Article

References (48)

1. Optimality theory, Gompertz's law and the disposable soma theory of senescence
2. Optimization models, quantitative genetics, and mutation
3. Selection in populations with overlapping generations. II. Relations between gene frequency and demographic variables
4. Age-specific inbreeding depression and components of genetic variance in relation to the evolution of senescence
5. Levelling of the grim reaper
6. Evolution, mutations, and human longevity: European royal and noble families
7. The effect of variation on fitness
8. The moulding of senescence by natural selection
9. Deceleration in the age pattern of mortality at older ages
10. Evolutionary genetics of male life history characters in Drosophila melanogaster
11. Terumi Mukai and the riddle of deleterious mutation rates
12. Effect of adult cohort density on age-specific mortality in Drosophila melanogaster
13. A population genetic model for the evolution of synonymous codon usage: Patterns and predictions
14. Old age and natural death
15. Evolutionary theory predicts late-life mortality plateaus
16. The genetic variance for viability and its components in a local population of Drosophila melanogaster
17. Sex-specific quantitative trait loci affecting longevity in Drosophila melanogaster
18. Optimality, mutation and the evolution of ageing
19. Messages from mortality: The evolution of death rates in the old
20. Mortality plateaus and the evolution of senescence: Why are old-age mortality rates so low?
21. The influence of environmentally induced heterogeneity on age-specific variance for mortality rates
22. Age-specific properties of spontaneous mutations affecting mortality in Drosophila melanogaster
23. The evolution of age-specific mortality rates in Drosophila melanogaster among unselected lines
24. Mutation and senescence: Where genetics and demography meet
25. Age-specific patterns of genetic variance in Drosophila melanogaster. I. Mortality
26. Evolutionary theories of aging: Confirmation of a fundamental prediction, with implications for the genetic basis and evolution of life span
27. Towards an evolutionary demography
28. Genetics of life history in Drosophila melanogaster. I. Sib analysis of adult females
29. Ageing and immortality
30. A delayed wave of death from reproduction in Drosophila
31. Towards reconciling inferences concerning genetic variation in senescence in Drosophila
32. Age-specific patterns of genetic variance in Drosophila melanogaster. II. Fecundity and its genetic covariance with age-specific mortality
33. Trajectories of mortality at advanced ages
34. Evolutionary demographic models for mortality plateaus
35. Pleiotropy, natural selection and the evolution of senescence
36. The evolutionary genetics of ageing and longevity