Evidence that OGG1 glycosylase protects neurons against oxidative DNA damage and cell death under ischemic conditions

Journal of Cerebral Blood Flow and Metabolism

Volumn 31, Issue 2, 2011, Pages 680-692

  Liu, Dong ^a   Croteau, Deborah L ^a   Souza Pinto, Nadja ^a,b   Pitta, Michael ^a   Tian, Jingyan ^a   Wu, Christopher ^a   Jiang, Haiyang ^a   Mustafa, Khadija ^a   Keijzers, Guido ^a   Bohr, Vilhelm A ^a   Mattson, Mark P ^a  

^a NATIONAL INSTITUTE ON AGING   (United States)

^b UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

8 oxoG; BER; DNA repair; Drp1; focal ischemic stroke; mitochondria; OGG1; XRCC1

Indexed keywords

7,8 DIHYDRO 8 OXOGUANINE DNA GLYCOSYLASE; DNA GLYCOSYLTRANSFERASE; DYNAMIN; DYNAMIN RELATED PROTEIN 1; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BEHAVIOR DISORDER; BRAIN CELL; BRAIN NERVE CELL; CELL DEATH; CELL NUCLEUS; CELL SURVIVAL; DNA DAMAGE; EMBRYO; EXCISION REPAIR; FRAGMENTATION REACTION; HEMISPHERE; ISCHEMIA; MALE; MEMBRANE POTENTIAL; METABOLIC STRESS; MIDDLE CEREBRAL ARTERY OCCLUSION; MITOCHONDRION; MOUSE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN FUNCTION; STROKE;

ANIMALS; BEHAVIOR, ANIMAL; BLOTTING, WESTERN; BRAIN ISCHEMIA; CELL DEATH; CELL NUCLEUS; CELL SURVIVAL; CELLS, CULTURED; DNA DAMAGE; DNA GLYCOSYLASES; DNA REPAIR; DNA, MITOCHONDRIAL; FLUORESCENT ANTIBODY TECHNIQUE; IN SITU NICK-END LABELING; MICE; MICE, KNOCKOUT; MITOCHONDRIA; NEURONS; OXIDATIVE STRESS; STROKE;

EID: 79551649906     PISSN: 0271678X     EISSN: None     Source Type: Journal    
DOI: 10.1038/jcbfm.2010.147     Document Type: Article

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