-
1
-
-
79960363432
-
DNA damage response and transcription
-
Lagerwerf S., Vrouwe M.G., Overmeer R.M., Fousteri M.I., Mullenders L.H.F. DNA damage response and transcription. DNA Repair 2011, 10:743-750.
-
(2011)
DNA Repair
, vol.10
, pp. 743-750
-
-
Lagerwerf, S.1
Vrouwe, M.G.2
Overmeer, R.M.3
Fousteri, M.I.4
Mullenders, L.H.F.5
-
2
-
-
11144357255
-
Cellular machineries for chromosomal DNA repair
-
Peterson C.L., Côté J. Cellular machineries for chromosomal DNA repair. Genes Dev. 2004, 18:602-616.
-
(2004)
Genes Dev.
, vol.18
, pp. 602-616
-
-
Peterson, C.L.1
Côté, J.2
-
3
-
-
77449086623
-
DNA resection in eukaryotes: deciding how to fix the break
-
Huertas P. DNA resection in eukaryotes: deciding how to fix the break. Nat. Struct. Mol. Biol. 2010, 17:11-16.
-
(2010)
Nat. Struct. Mol. Biol.
, vol.17
, pp. 11-16
-
-
Huertas, P.1
-
4
-
-
0035902108
-
Genome maintenance mechanisms for preventing cancer
-
Hoeijmakers J.H. Genome maintenance mechanisms for preventing cancer. Nature 2001, 411:366-374.
-
(2001)
Nature
, vol.411
, pp. 366-374
-
-
Hoeijmakers, J.H.1
-
5
-
-
33747195353
-
Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors
-
Takahashi K., Yamanaka S. Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors. Cell 2006, 126:663-676.
-
(2006)
Cell
, vol.126
, pp. 663-676
-
-
Takahashi, K.1
Yamanaka, S.2
-
6
-
-
38049024575
-
The role of DNA damage repair in aging of adult stem cells
-
Kenyon J., Gerson S.L. The role of DNA damage repair in aging of adult stem cells. Nucleic Acids Res. 2007, 35:7557-7565.
-
(2007)
Nucleic Acids Res.
, vol.35
, pp. 7557-7565
-
-
Kenyon, J.1
Gerson, S.L.2
-
7
-
-
0942278966
-
The eukaryotic nucleotide excision repair pathway
-
Costa R.M.A., Chiganças V., Galhardo R.S., Carvalho H., Menck C.F.M. The eukaryotic nucleotide excision repair pathway. Biochimie 2003, 85:1083-1099.
-
(2003)
Biochimie
, vol.85
, pp. 1083-1099
-
-
Costa, R.M.A.1
Chiganças, V.2
Galhardo, R.S.3
Carvalho, H.4
Menck, C.F.M.5
-
8
-
-
38049164275
-
Eukaryotic nucleotide excision repair: from understanding mechanisms to influencing biology
-
Shuck S.C., Short E.A., Turchi J.J. Eukaryotic nucleotide excision repair: from understanding mechanisms to influencing biology. Cell Res. 2008, 18:64-72.
-
(2008)
Cell Res.
, vol.18
, pp. 64-72
-
-
Shuck, S.C.1
Short, E.A.2
Turchi, J.J.3
-
9
-
-
77952469080
-
The bright and the dark sides of DNA repair in stem cells
-
Frosina G. The bright and the dark sides of DNA repair in stem cells. J. Biomed. Biotechnol. 2010, 2010:845396.
-
(2010)
J. Biomed. Biotechnol.
, vol.2010
, pp. 845396
-
-
Frosina, G.1
-
10
-
-
0033961277
-
Terminally differentiated human neurons repair transcribed genes but display attenuated global DNA repair and modulation of repair gene expression
-
Nouspikel T., Hanawalt P.C. Terminally differentiated human neurons repair transcribed genes but display attenuated global DNA repair and modulation of repair gene expression. Mol. Cell. Biol. 2000, 20:1562-1570.
-
(2000)
Mol. Cell. Biol.
, vol.20
, pp. 1562-1570
-
-
Nouspikel, T.1
Hanawalt, P.C.2
-
11
-
-
33750821636
-
Impaired nucleotide excision repair upon macrophage differentiation is corrected by E1 ubiquitin-activating enzyme
-
Nouspikel T., Hanawalt P.C. Impaired nucleotide excision repair upon macrophage differentiation is corrected by E1 ubiquitin-activating enzyme. Proc. Natl. Acad. Sci. U.S.A. 2006, 103:16188-16193.
-
(2006)
Proc. Natl. Acad. Sci. U.S.A.
, vol.103
, pp. 16188-16193
-
-
Nouspikel, T.1
Hanawalt, P.C.2
-
12
-
-
34247178359
-
DNA repair in differentiated cells: some new answers to old questions
-
Nouspikel T. DNA repair in differentiated cells: some new answers to old questions. Neuroscience 2007, 145:1213-1221.
-
(2007)
Neuroscience
, vol.145
, pp. 1213-1221
-
-
Nouspikel, T.1
-
14
-
-
33847007529
-
The mechanics of base excision repair, and its relationship to aging and disease
-
Wilson D.M., Bohr V.A. The mechanics of base excision repair, and its relationship to aging and disease. DNA Repair 2007, 6:544-559.
-
(2007)
DNA Repair
, vol.6
, pp. 544-559
-
-
Wilson, D.M.1
Bohr, V.A.2
-
15
-
-
34247625537
-
The capacity to remove 8-oxoG is enhanced in newborn neural stem/progenitor cells and decreases in juvenile mice and upon cell differentiation
-
Hildrestrand G.A., Diep D.B., Kunke D., Bolstad N., Bjørås M., Krauss S., et al. The capacity to remove 8-oxoG is enhanced in newborn neural stem/progenitor cells and decreases in juvenile mice and upon cell differentiation. DNA Repair 2007, 6:723-732.
-
(2007)
DNA Repair
, vol.6
, pp. 723-732
-
-
Hildrestrand, G.A.1
Diep, D.B.2
Kunke, D.3
Bolstad, N.4
Bjørås, M.5
Krauss, S.6
-
16
-
-
48149114323
-
Widespread distribution of DNA glycosylases removing oxidative DNA lesions in human and rodent brains
-
Rolseth V., Rundén-Pran E., Luna L., McMurray C., Bjørås M., Ottersen O.P. Widespread distribution of DNA glycosylases removing oxidative DNA lesions in human and rodent brains. DNA Repair 2008, 7:1578-1588.
-
(2008)
DNA Repair
, vol.7
, pp. 1578-1588
-
-
Rolseth, V.1
Rundén-Pran, E.2
Luna, L.3
McMurray, C.4
Bjørås, M.5
Ottersen, O.P.6
-
17
-
-
66449104386
-
Expression patterns of Neil3 during embryonic brain development and neoplasia
-
Hildrestrand G., Neurauter C., Diep D., Castellanos C., Krauss S., Bjoras M., et al. Expression patterns of Neil3 during embryonic brain development and neoplasia. BMC Neurosci. 2009, 10:45.
-
(2009)
BMC Neurosci.
, vol.10
, pp. 45
-
-
Hildrestrand, G.1
Neurauter, C.2
Diep, D.3
Castellanos, C.4
Krauss, S.5
Bjoras, M.6
-
18
-
-
36749007778
-
Terminally differentiated muscle cells are defective in base excision DNA repair and hypersensitive to oxygen injury
-
Narciso L., Fortini P., Pajalunga D., Franchitto A., Liu P., Degan P., et al. Terminally differentiated muscle cells are defective in base excision DNA repair and hypersensitive to oxygen injury. Proc. Natl. Acad. Sci. U.S.A. 2007, 104:17010-17015.
-
(2007)
Proc. Natl. Acad. Sci. U.S.A.
, vol.104
, pp. 17010-17015
-
-
Narciso, L.1
Fortini, P.2
Pajalunga, D.3
Franchitto, A.4
Liu, P.5
Degan, P.6
-
19
-
-
84864487729
-
Homologous recombination and its regulation
-
Krejci L., Altmannova V., Spirek M., Zhao X. Homologous recombination and its regulation. Nucleic Acids Res. 2012, 40(13):5795-5818.
-
(2012)
Nucleic Acids Res.
, vol.40
, Issue.13
, pp. 5795-5818
-
-
Krejci, L.1
Altmannova, V.2
Spirek, M.3
Zhao, X.4
-
20
-
-
70350088548
-
Mechanisms of double-strand break repair in somatic mammalian cells
-
Hartlerode A.J., Scully R. Mechanisms of double-strand break repair in somatic mammalian cells. Biochem. J. 2009, 423:157-168.
-
(2009)
Biochem. J.
, vol.423
, pp. 157-168
-
-
Hartlerode, A.J.1
Scully, R.2
-
21
-
-
77953229115
-
The mechanism of double-strand DNA break repair by the nonhomologous DNA end-joining pathway
-
Lieber M.R. The mechanism of double-strand DNA break repair by the nonhomologous DNA end-joining pathway. Annu. Rev. Biochem. 2010, 79:181-211.
-
(2010)
Annu. Rev. Biochem.
, vol.79
, pp. 181-211
-
-
Lieber, M.R.1
-
22
-
-
0042839614
-
Mechanism and regulation of human non-homologous DNA end-joining
-
Lieber M.R., Ma Y., Pannicke U., Schwarz K. Mechanism and regulation of human non-homologous DNA end-joining. Nat. Rev. Mol. Cell Biol. 2003, 4:712-720.
-
(2003)
Nat. Rev. Mol. Cell Biol.
, vol.4
, pp. 712-720
-
-
Lieber, M.R.1
Ma, Y.2
Pannicke, U.3
Schwarz, K.4
-
23
-
-
34548319709
-
Age-related transcription levels of KU70, MGST1 and BIK in CD34+ hematopoietic stem and progenitor cells
-
Prall W.C., Czibere A., Jäger M., Spentzos D., Libermann T.A., Gattermann N., et al. Age-related transcription levels of KU70, MGST1 and BIK in CD34+ hematopoietic stem and progenitor cells. Mech. Ageing Dev. 2007, 128:503-510.
-
(2007)
Mech. Ageing Dev.
, vol.128
, pp. 503-510
-
-
Prall, W.C.1
Czibere, A.2
Jäger, M.3
Spentzos, D.4
Libermann, T.A.5
Gattermann, N.6
-
24
-
-
77953121698
-
Bcl-2 and accelerated DNA repair mediates resistance of hair follicle bulge stem cells to DNA-damage-induced cell death
-
Sotiropoulou P.A., Candi A., Mascre G., De Clercq S., Youssef K.K., Lapouge G., et al. Bcl-2 and accelerated DNA repair mediates resistance of hair follicle bulge stem cells to DNA-damage-induced cell death. Nat. Cell Biol. 2010, 12:572-582.
-
(2010)
Nat. Cell Biol.
, vol.12
, pp. 572-582
-
-
Sotiropoulou, P.A.1
Candi, A.2
Mascre, G.3
De Clercq, S.4
Youssef, K.K.5
Lapouge, G.6
-
25
-
-
33750083332
-
Mechanisms in eukaryotic mismatch repair
-
Modrich P. Mechanisms in eukaryotic mismatch repair. J. Biol. Chem. 2006, 281:30305-30309.
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 30305-30309
-
-
Modrich, P.1
-
26
-
-
34447313898
-
Methylation damage response in hematopoietic progenitor cells
-
Casorelli I., Pelosi E., Biffoni M., Cerio A.M., Peschle C., Testa U., et al. Methylation damage response in hematopoietic progenitor cells. DNA Repair 2007, 6:1170-1178.
-
(2007)
DNA Repair
, vol.6
, pp. 1170-1178
-
-
Casorelli, I.1
Pelosi, E.2
Biffoni, M.3
Cerio, A.M.4
Peschle, C.5
Testa, U.6
-
28
-
-
80053449547
-
The Fanconi anemia pathway is downregulated upon macrophage differentiation through two distinct mechanisms
-
Lu W.-T., Lemonidis K., Drayton R.M., Nouspikel T. The Fanconi anemia pathway is downregulated upon macrophage differentiation through two distinct mechanisms. Cell Cycle 2011, 10:3300-3310.
-
(2011)
Cell Cycle
, vol.10
, pp. 3300-3310
-
-
Lu, W.-T.1
Lemonidis, K.2
Drayton, R.M.3
Nouspikel, T.4
-
29
-
-
33744967770
-
Stringent regulation of DNA repair during human hematopoietic differentiation: a gene expression and functional analysis
-
Bracker T.U., Giebel B., Spanholtz J., Sorg U.R., Klein-Hitpass L., Moritz T., et al. Stringent regulation of DNA repair during human hematopoietic differentiation: a gene expression and functional analysis. Stem Cells 2006, 24:722-730.
-
(2006)
Stem Cells
, vol.24
, pp. 722-730
-
-
Bracker, T.U.1
Giebel, B.2
Spanholtz, J.3
Sorg, U.R.4
Klein-Hitpass, L.5
Moritz, T.6
-
30
-
-
7244250309
-
Regulation of oxidative stress by ATM is required for self-renewal of haematopoietic stem cells
-
Ito K., Hirao A., Arai F., Matsuoka S., Takubo K., Hamaguchi I., et al. Regulation of oxidative stress by ATM is required for self-renewal of haematopoietic stem cells. Nature 2004, 431:997-1002.
-
(2004)
Nature
, vol.431
, pp. 997-1002
-
-
Ito, K.1
Hirao, A.2
Arai, F.3
Matsuoka, S.4
Takubo, K.5
Hamaguchi, I.6
-
31
-
-
78149408058
-
Empowering self-renewal and differentiation: the role of mitochondria in stem cells
-
Rehman J. Empowering self-renewal and differentiation: the role of mitochondria in stem cells. J. Mol. Med. 2010, 88:981-986.
-
(2010)
J. Mol. Med.
, vol.88
, pp. 981-986
-
-
Rehman, J.1
-
32
-
-
33645730667
-
Reactive oxygen species act through p38 MAPK to limit the lifespan of hematopoietic stem cells
-
Ito K., Hirao A., Arai F., Takubo K., Matsuoka S., Miyamoto K., et al. Reactive oxygen species act through p38 MAPK to limit the lifespan of hematopoietic stem cells. Nat. Med. 2006, 12:446-451.
-
(2006)
Nat. Med.
, vol.12
, pp. 446-451
-
-
Ito, K.1
Hirao, A.2
Arai, F.3
Takubo, K.4
Matsuoka, S.5
Miyamoto, K.6
-
33
-
-
70349592516
-
The relationship between pluripotency and mitochondrial DNA proliferation during early embryo development and embryonic stem cell differentiation
-
Facucho-Oliveira J.M., St John J.C. The relationship between pluripotency and mitochondrial DNA proliferation during early embryo development and embryonic stem cell differentiation. Stem Cell Rev. 2009, 5:140-158.
-
(2009)
Stem Cell Rev.
, vol.5
, pp. 140-158
-
-
Facucho-Oliveira, J.M.1
St John, J.C.2
-
34
-
-
51349120502
-
Regulation of reactive oxygen species and genomic stability in hematopoietic stem cells
-
Naka K., Muraguchi T., Hoshii T., Hirao A. Regulation of reactive oxygen species and genomic stability in hematopoietic stem cells. Antioxid. Redox Signal. 2008, 10:1883-1894.
-
(2008)
Antioxid. Redox Signal.
, vol.10
, pp. 1883-1894
-
-
Naka, K.1
Muraguchi, T.2
Hoshii, T.3
Hirao, A.4
-
35
-
-
0038418869
-
Chk1 and Chk2 kinases in checkpoint control and cancer
-
Bartek J., Lukas J. Chk1 and Chk2 kinases in checkpoint control and cancer. Cancer Cell 2003, 3:421-429.
-
(2003)
Cancer Cell
, vol.3
, pp. 421-429
-
-
Bartek, J.1
Lukas, J.2
-
38
-
-
70350504453
-
The DNA-damage response in human biology and disease
-
Jackson S.P., Bartek J. The DNA-damage response in human biology and disease. Nature 2009, 461:1071-1078.
-
(2009)
Nature
, vol.461
, pp. 1071-1078
-
-
Jackson, S.P.1
Bartek, J.2
-
39
-
-
77958498222
-
The ATM-Chk2 and ATR-Chk1 pathways in DNA damage signaling and cancer
-
Smith J., Tho L.M., Xu N., Gillespie D.A. The ATM-Chk2 and ATR-Chk1 pathways in DNA damage signaling and cancer. Adv. Cancer Res. 2010, 108:73-112.
-
(2010)
Adv. Cancer Res.
, vol.108
, pp. 73-112
-
-
Smith, J.1
Tho, L.M.2
Xu, N.3
Gillespie, D.A.4
-
40
-
-
38049150586
-
The DNA damage response pathways: at the crossroad of protein modifications
-
Huen M.S.Y., Chen J. The DNA damage response pathways: at the crossroad of protein modifications. Cell Res. 2008, 18:8-16.
-
(2008)
Cell Res.
, vol.18
, pp. 8-16
-
-
Huen, M.S.Y.1
Chen, J.2
-
41
-
-
0037178748
-
Interfaces between the detection, signaling, and repair of DNA damage
-
Rouse J., Jackson S.P. Interfaces between the detection, signaling, and repair of DNA damage. Science 2002, 297:547-551.
-
(2002)
Science
, vol.297
, pp. 547-551
-
-
Rouse, J.1
Jackson, S.P.2
-
42
-
-
65849336044
-
At loose ends: resecting a double-strand break
-
Bernstein K.A., Rothstein R. At loose ends: resecting a double-strand break. Cell 2009, 137:807-810.
-
(2009)
Cell
, vol.137
, pp. 807-810
-
-
Bernstein, K.A.1
Rothstein, R.2
-
43
-
-
35848951634
-
DNA damage and cellular differentiation: more questions than responses
-
Simonatto M., Latella L., Puri P.L. DNA damage and cellular differentiation: more questions than responses. J. Cell. Physiol. 2007, 213:642-648.
-
(2007)
J. Cell. Physiol.
, vol.213
, pp. 642-648
-
-
Simonatto, M.1
Latella, L.2
Puri, P.L.3
-
44
-
-
34250001450
-
DNA repair is limiting for haematopoietic stem cells during ageing
-
Nijnik A., Woodbine L., Marchetti C., Dawson S., Lambe T., Liu C., et al. DNA repair is limiting for haematopoietic stem cells during ageing. Nature 2007, 447:686-690.
-
(2007)
Nature
, vol.447
, pp. 686-690
-
-
Nijnik, A.1
Woodbine, L.2
Marchetti, C.3
Dawson, S.4
Lambe, T.5
Liu, C.6
-
45
-
-
0041440074
-
Repopulating defect of mismatch repair-deficient hematopoietic stem cells
-
Reese J.S., Liu L., Gerson S.L. Repopulating defect of mismatch repair-deficient hematopoietic stem cells. Blood 2003, 102:1626-1633.
-
(2003)
Blood
, vol.102
, pp. 1626-1633
-
-
Reese, J.S.1
Liu, L.2
Gerson, S.L.3
-
46
-
-
33748043345
-
Hematopoietic dysfunction in a mouse model for Fanconi anemia group D1
-
Navarro S., Meza N.W., Quintana-Bustamante O., Casado J.A., Jacome A., McAllister K., et al. Hematopoietic dysfunction in a mouse model for Fanconi anemia group D1. Mol. Ther. 2006, 14:525-535.
-
(2006)
Mol. Ther.
, vol.14
, pp. 525-535
-
-
Navarro, S.1
Meza, N.W.2
Quintana-Bustamante, O.3
Casado, J.A.4
Jacome, A.5
McAllister, K.6
-
47
-
-
79960022038
-
Mitochondrial DNA damage level determines neural stem cell differentiation fate
-
Wang W., Esbensen Y., Kunke D., Suganthan R., Rachek L., Bjørås M., et al. Mitochondrial DNA damage level determines neural stem cell differentiation fate. J. Neurosci. 2011, 31:9746-9751.
-
(2011)
J. Neurosci.
, vol.31
, pp. 9746-9751
-
-
Wang, W.1
Esbensen, Y.2
Kunke, D.3
Suganthan, R.4
Rachek, L.5
Bjørås, M.6
-
48
-
-
78650979504
-
DNA-damage response in tissue-specific and cancer stem cells
-
Blanpain C., Mohrin M., Sotiropoulou P.A., Passegu E. DNA-damage response in tissue-specific and cancer stem cells. Cell Stem Cell. 2011, 8:16-29.
-
(2011)
Cell Stem Cell.
, vol.8
, pp. 16-29
-
-
Blanpain, C.1
Mohrin, M.2
Sotiropoulou, P.A.3
Passegu, E.4
-
49
-
-
84870991474
-
DNA damage response by single-strand breaks in terminally differentiated muscle cells and the control of muscle integrity
-
(Epub ahead of print)
-
Fortini P., Ferretti C., Pascucci B., Narciso L., Pajalunga D., Puggioni E.M.R., et al. DNA damage response by single-strand breaks in terminally differentiated muscle cells and the control of muscle integrity. Cell Death Differ. 2012, (Epub ahead of print). 10.1038/cdd.2012.53.
-
(2012)
Cell Death Differ.
-
-
Fortini, P.1
Ferretti, C.2
Pascucci, B.3
Narciso, L.4
Pajalunga, D.5
Puggioni, E.M.R.6
-
50
-
-
79952003900
-
DNA damage response in adult stem cells: pathways and consequences
-
Mandal P.K., Blanpain C., Rossi D.J. DNA damage response in adult stem cells: pathways and consequences. Nat. Rev. Mol. Cell Biol. 2011, 12:198-202.
-
(2011)
Nat. Rev. Mol. Cell Biol.
, vol.12
, pp. 198-202
-
-
Mandal, P.K.1
Blanpain, C.2
Rossi, D.J.3
-
51
-
-
0035499267
-
Stem cells, cancer, and cancer stem cells
-
Reya T., Morrison S.J., Clarke M.F., Weissman I.L. Stem cells, cancer, and cancer stem cells. Nature 2001, 414:105-111.
-
(2001)
Nature
, vol.414
, pp. 105-111
-
-
Reya, T.1
Morrison, S.J.2
Clarke, M.F.3
Weissman, I.L.4
-
53
-
-
33750313208
-
Cancer stem cells-perspectives on current status and future directions: AACR workshop on cancer stem cells
-
Clarke M.F., Dick J.E., Dirks P.B., Eaves C.J., Jamieson C.H.M., Jones D.L., et al. Cancer stem cells-perspectives on current status and future directions: AACR workshop on cancer stem cells. Cancer Res. 2006, 66:9339-9344.
-
(2006)
Cancer Res.
, vol.66
, pp. 9339-9344
-
-
Clarke, M.F.1
Dick, J.E.2
Dirks, P.B.3
Eaves, C.J.4
Jamieson, C.H.M.5
Jones, D.L.6
-
54
-
-
33845664398
-
Primitive, quiescent and difficult to kill: the role of non-proliferating stem cells in chronic myeloid leukemia
-
Barnes D.J., Melo J.V. Primitive, quiescent and difficult to kill: the role of non-proliferating stem cells in chronic myeloid leukemia. Cell Cycle 2006, 5(24):2862-2866.
-
(2006)
Cell Cycle
, vol.5
, Issue.24
, pp. 2862-2866
-
-
Barnes, D.J.1
Melo, J.V.2
-
55
-
-
79952370202
-
The cancer stem cell: premises, promises and challenges
-
Clevers H. The cancer stem cell: premises, promises and challenges. Nat. Med. 2011, 17:313-319.
-
(2011)
Nat. Med.
, vol.17
, pp. 313-319
-
-
Clevers, H.1
-
56
-
-
70349974841
-
The pyridinylfuranopyrimidine inhibitor PI-103, chemosensitizes glioblastoma cells for apoptosis by inhibiting DNA repair
-
Westhoff M.-A., Kandenwein J.A., Karl S., Vellanki S.H.K., Braun V., Eramo A., et al. The pyridinylfuranopyrimidine inhibitor PI-103, chemosensitizes glioblastoma cells for apoptosis by inhibiting DNA repair. Oncogene 2009, 28:3586-3596.
-
(2009)
Oncogene
, vol.28
, pp. 3586-3596
-
-
Westhoff, M.-A.1
Kandenwein, J.A.2
Karl, S.3
Vellanki, S.H.K.4
Braun, V.5
Eramo, A.6
-
57
-
-
34547114987
-
Inhibition of phosphatidylinositol-3-OH kinase/Akt signaling impairs DNA repair in glioblastoma cells following ionizing radiation
-
Kao G.D., Jiang Z., Fernandes A.M., Gupta A.K., Maity A. Inhibition of phosphatidylinositol-3-OH kinase/Akt signaling impairs DNA repair in glioblastoma cells following ionizing radiation. J. Biol. Chem. 2007, 282:21206-21212.
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 21206-21212
-
-
Kao, G.D.1
Jiang, Z.2
Fernandes, A.M.3
Gupta, A.K.4
Maity, A.5
-
58
-
-
65249093701
-
DNA damage mediated s and g(2) checkpoints in human embryonal carcinoma cells
-
Wang X., Lui V.C.H., Poon R.T.P., Lu P., Poon R.Y.C. DNA damage mediated s and g(2) checkpoints in human embryonal carcinoma cells. Stem Cells 2009, 27:568-576.
-
(2009)
Stem Cells
, vol.27
, pp. 568-576
-
-
Wang, X.1
Lui, V.C.H.2
Poon, R.T.P.3
Lu, P.4
Poon, R.Y.C.5
-
59
-
-
33845317573
-
Glioma stem cells promote radioresistance by preferential activation of the DNA damage response
-
Bao S., Wu Q., McLendon R.E., Hao Y., Shi Q., Hjelmeland A.B., et al. Glioma stem cells promote radioresistance by preferential activation of the DNA damage response. Nature 2006, 444:756-760.
-
(2006)
Nature
, vol.444
, pp. 756-760
-
-
Bao, S.1
Wu, Q.2
McLendon, R.E.3
Hao, Y.4
Shi, Q.5
Hjelmeland, A.B.6
-
61
-
-
33845914051
-
A new progeroid syndrome reveals that genotoxic stress suppresses the somatotroph axis
-
Niedernhofer L.J., Garinis G.A., Raams A., Lalai A.S., Robinson A.R., Appeldoorn E., et al. A new progeroid syndrome reveals that genotoxic stress suppresses the somatotroph axis. Nature 2006, 444:1038-1043.
-
(2006)
Nature
, vol.444
, pp. 1038-1043
-
-
Niedernhofer, L.J.1
Garinis, G.A.2
Raams, A.3
Lalai, A.S.4
Robinson, A.R.5
Appeldoorn, E.6
-
62
-
-
14544268189
-
DNA repair defects in stem cell function and aging
-
Park Y., Gerson S.L. DNA repair defects in stem cell function and aging. Annu. Rev. Med. 2004, 56:495-508.
-
(2004)
Annu. Rev. Med.
, vol.56
, pp. 495-508
-
-
Park, Y.1
Gerson, S.L.2
-
63
-
-
13944262937
-
Understanding the odd science of aging
-
Kirkwood T.B.L. Understanding the odd science of aging. Cell 2005, 120:437-447.
-
(2005)
Cell
, vol.120
, pp. 437-447
-
-
Kirkwood, T.B.L.1
-
64
-
-
49949152164
-
Nucleotide excision repair deficient mouse models and neurological disease
-
Niedernhofer L.J. Nucleotide excision repair deficient mouse models and neurological disease. DNA Repair 2008, 7:1180-1189.
-
(2008)
DNA Repair
, vol.7
, pp. 1180-1189
-
-
Niedernhofer, L.J.1
-
65
-
-
0037470542
-
Aging and genome maintenance lessons from the mouse?
-
Hasty P., Campisi J., Hoeijmakers J., van Steeg H., Vijg J. Aging and genome maintenance lessons from the mouse?. Science 2003, 299:1355-1359.
-
(2003)
Science
, vol.299
, pp. 1355-1359
-
-
Hasty, P.1
Campisi, J.2
Hoeijmakers, J.3
van Steeg, H.4
Vijg, J.5
-
66
-
-
79961207854
-
A review and appraisal of the DNA damage theory of ageing
-
Freitas A.A., de Magalhães J.P. A review and appraisal of the DNA damage theory of ageing. Mutat. Res. 2011, 728:12-22.
-
(2011)
Mutat. Res.
, vol.728
, pp. 12-22
-
-
Freitas, A.A.1
de Magalhães, J.P.2
-
67
-
-
79960341941
-
Premature aging and cancer in nucleotide excision repair-disorders
-
Diderich K., Alanazi M., Hoeijmakers J.H.J. Premature aging and cancer in nucleotide excision repair-disorders. DNA Repair 2011, 10:772-780.
-
(2011)
DNA Repair
, vol.10
, pp. 772-780
-
-
Diderich, K.1
Alanazi, M.2
Hoeijmakers, J.H.J.3
-
68
-
-
81855198154
-
DNA-damage accumulation and replicative arrest in Hutchinson-Gilford progeria syndrome
-
Musich P.R., Zou Y. DNA-damage accumulation and replicative arrest in Hutchinson-Gilford progeria syndrome. Biochem. Soc. Trans. 2011, 39:1764-1769.
-
(2011)
Biochem. Soc. Trans.
, vol.39
, pp. 1764-1769
-
-
Musich, P.R.1
Zou, Y.2
-
69
-
-
65549153127
-
A UV-sensitive syndrome patient with a specific CSA mutation reveals separable roles for CSA in response to UV and oxidative DNA damage
-
Nardo T., Oneda R., Spivak G., Vaz B., Mortier L., Thomas P., et al. A UV-sensitive syndrome patient with a specific CSA mutation reveals separable roles for CSA in response to UV and oxidative DNA damage. Proc. Natl. Acad. Sci. U.S.A. 2009, 106:6209-6214.
-
(2009)
Proc. Natl. Acad. Sci. U.S.A.
, vol.106
, pp. 6209-6214
-
-
Nardo, T.1
Oneda, R.2
Spivak, G.3
Vaz, B.4
Mortier, L.5
Thomas, P.6
-
70
-
-
45449093552
-
The role of Cockayne syndrome group B (CSB) protein in base excision repair and aging
-
Stevnsner T., Muftuoglu M., Aamann M.D., Bohr V.A. The role of Cockayne syndrome group B (CSB) protein in base excision repair and aging. Mech. Ageing Dev. 2008, 129:441-448.
-
(2008)
Mech. Ageing Dev.
, vol.129
, pp. 441-448
-
-
Stevnsner, T.1
Muftuoglu, M.2
Aamann, M.D.3
Bohr, V.A.4
-
71
-
-
34250682202
-
Deficient base excision repair of oxidative DNA damage induced by methylene blue plus visible light in xeroderma pigmentosum group C fibroblasts
-
Kassam S.N., Rainbow A.J. Deficient base excision repair of oxidative DNA damage induced by methylene blue plus visible light in xeroderma pigmentosum group C fibroblasts. Biochem. Biophys. Res. Commun. 2007, 359:1004-1009.
-
(2007)
Biochem. Biophys. Res. Commun.
, vol.359
, pp. 1004-1009
-
-
Kassam, S.N.1
Rainbow, A.J.2
-
72
-
-
33748944305
-
New functions of XPC in the protection of human skin cells from oxidative damage
-
D'Errico M., Parlanti E., Teson M., de Jesus B.M.B., Degan P., Calcagnile A., et al. New functions of XPC in the protection of human skin cells from oxidative damage. EMBO J. 2006, 25:4305-4315.
-
(2006)
EMBO J.
, vol.25
, pp. 4305-4315
-
-
D'Errico, M.1
Parlanti, E.2
Teson, M.3
de Jesus, B.M.B.4
Degan, P.5
Calcagnile, A.6
-
74
-
-
34250007142
-
Deficiencies in DNA damage repair limit the function of haematopoietic stem cells with age
-
Rossi D.J., Bryder D., Seita J., Nussenzweig A., Hoeijmakers J., Weissman I.L. Deficiencies in DNA damage repair limit the function of haematopoietic stem cells with age. Nature 2007, 447:725-729.
-
(2007)
Nature
, vol.447
, pp. 725-729
-
-
Rossi, D.J.1
Bryder, D.2
Seita, J.3
Nussenzweig, A.4
Hoeijmakers, J.5
Weissman, I.L.6
-
75
-
-
77149172083
-
Proteins of nucleotide and base excision repair pathways interact in mitochondria to protect from loss of subcutaneous fat, a hallmark of aging
-
Kamenisch Y., Fousteri M., Knoch J., von Thaler A.K., Fehrenbacher B., Kato H., Becker T., Dollé M.E., Kuiper R., Majora M., Schaller M., van der Horst G.T., van Steeg H., Röcken M., Rapaport D., Krutmann J., Mullenders L.H., Berneburg M. Proteins of nucleotide and base excision repair pathways interact in mitochondria to protect from loss of subcutaneous fat, a hallmark of aging. J. Exp. Med. 2010, 207:379-390.
-
(2010)
J. Exp. Med.
, vol.207
, pp. 379-390
-
-
Kamenisch, Y.1
Fousteri, M.2
Knoch, J.3
von Thaler, A.K.4
Fehrenbacher, B.5
Kato, H.6
Becker, T.7
Dollé, M.E.8
Kuiper, R.9
Majora, M.10
Schaller, M.11
van der Horst, G.T.12
van Steeg, H.13
Röcken, M.14
Rapaport, D.15
Krutmann, J.16
Mullenders, L.H.17
Berneburg, M.18
-
76
-
-
84861749572
-
Cockayne syndrome group B protein prevents the accumulation of damaged mitochondria by promoting mitochondrial autophagy
-
Scheibye-Knudsen M., Ramamoorthy M., Sykora P., Maynard S., Lin P.-C., Minor R.K., et al. Cockayne syndrome group B protein prevents the accumulation of damaged mitochondria by promoting mitochondrial autophagy. J. Exp. Med. 2012, 209:855-869.
-
(2012)
J. Exp. Med.
, vol.209
, pp. 855-869
-
-
Scheibye-Knudsen, M.1
Ramamoorthy, M.2
Sykora, P.3
Maynard, S.4
Lin, P.-C.5
Minor, R.K.6
-
77
-
-
84856695688
-
Muscle-derived stem/progenitor cell dysfunction limits healthspan and lifespan in a murine progeria model
-
Lavasani M., Robinson A.R., Lu A., Song M., Feduska J.M., Ahani B., et al. Muscle-derived stem/progenitor cell dysfunction limits healthspan and lifespan in a murine progeria model. Nat. Commun. 2012, 3:608.
-
(2012)
Nat. Commun.
, vol.3
, pp. 608
-
-
Lavasani, M.1
Robinson, A.R.2
Lu, A.3
Song, M.4
Feduska, J.M.5
Ahani, B.6
-
78
-
-
13944261231
-
Rejuvenation of aged progenitor cells by exposure to a young systemic environment
-
Conboy I.M., Conboy M.J., Wagers A.J., Girma E.R., Weissman I.L., Rando T.A. Rejuvenation of aged progenitor cells by exposure to a young systemic environment. Nature 2005, 433:760-764.
-
(2005)
Nature
, vol.433
, pp. 760-764
-
-
Conboy, I.M.1
Conboy, M.J.2
Wagers, A.J.3
Girma, E.R.4
Weissman, I.L.5
Rando, T.A.6
-
79
-
-
13944278132
-
Mitochondria, oxidants, and aging
-
Balaban R.S., Nemoto S., Finkel T. Mitochondria, oxidants, and aging. Cell 2005, 120:483-495.
-
(2005)
Cell
, vol.120
, pp. 483-495
-
-
Balaban, R.S.1
Nemoto, S.2
Finkel, T.3
-
80
-
-
55049090534
-
Human embryonic stem cells have enhanced repair of multiple forms of DNA damage
-
Maynard S., Swistowska A.M., Lee J.W., Liu Y., Liu S.-T., Da Cruz A.B., et al. Human embryonic stem cells have enhanced repair of multiple forms of DNA damage. Stem Cells 2008, 26:2266-2274.
-
(2008)
Stem Cells
, vol.26
, pp. 2266-2274
-
-
Maynard, S.1
Swistowska, A.M.2
Lee, J.W.3
Liu, Y.4
Liu, S.-T.5
Da Cruz, A.B.6
-
81
-
-
78149445840
-
DNA damage responses in human induced pluripotent stem cells and embryonic stem cells
-
Momcilovic O., Knobloch L., Fornsaglio J., Varum S., Easley C., Schatten G. DNA damage responses in human induced pluripotent stem cells and embryonic stem cells. PLoS ONE 2010, 5:e13410.
-
(2010)
PLoS ONE
, vol.5
-
-
Momcilovic, O.1
Knobloch, L.2
Fornsaglio, J.3
Varum, S.4
Easley, C.5
Schatten, G.6
-
82
-
-
77956327999
-
Dynamic dependence on ATR and ATM for double-strand break repair in human embryonic stem cells and neural descendants
-
Adams B.R., Golding S.E., Rao R.R., Valerie K. Dynamic dependence on ATR and ATM for double-strand break repair in human embryonic stem cells and neural descendants. PLoS ONE 2010, 5:e10001.
-
(2010)
PLoS ONE
, vol.5
-
-
Adams, B.R.1
Golding, S.E.2
Rao, R.R.3
Valerie, K.4
-
83
-
-
78049381196
-
Mouse embryonic stem cells but not somatic cells, predominantly use homologous recombination to repair double-strand DNA breaks
-
Tichy E.D., Pillai R., Deng L., Liang L., Tischfield J., Schwemberger S.J., Babcock G.F., Stambrook P.J. Mouse embryonic stem cells but not somatic cells, predominantly use homologous recombination to repair double-strand DNA breaks. Stem Cells Dev. 2010, 19:1699-1711.
-
(2010)
Stem Cells Dev.
, vol.19
, pp. 1699-1711
-
-
Tichy, E.D.1
Pillai, R.2
Deng, L.3
Liang, L.4
Tischfield, J.5
Schwemberger, S.J.6
Babcock, G.F.7
Stambrook, P.J.8
-
84
-
-
48149108735
-
Mouse but not human embryonic stem cells are deficient in rejoining of ionizing radiation-induced DNA double-strand breaks
-
Bañuelos C.A., Banáth J.P., MacPhail S.H., Zhao J., Eaves C.A., O'Connor M.D., et al. Mouse but not human embryonic stem cells are deficient in rejoining of ionizing radiation-induced DNA double-strand breaks. DNA Repair 2008, 7:1471-1483.
-
(2008)
DNA Repair
, vol.7
, pp. 1471-1483
-
-
Bañuelos, C.A.1
Banáth, J.P.2
MacPhail, S.H.3
Zhao, J.4
Eaves, C.A.5
O'Connor, M.D.6
-
85
-
-
79952114962
-
ATM-independent, high-fidelity nonhomologous end joining predominates in human embryonic stem cells
-
Adams B.R., Hawkins A.J., Povirk L.F., Valerie K. ATM-independent, high-fidelity nonhomologous end joining predominates in human embryonic stem cells. Aging 2010, 2:582-596.
-
(2010)
Aging
, vol.2
, pp. 582-596
-
-
Adams, B.R.1
Hawkins, A.J.2
Povirk, L.F.3
Valerie, K.4
-
86
-
-
81055127050
-
Error-prone nonhomologous end joining repair operates in human pluripotent stem cells during late G2
-
Bogomazova AN K.S., Lagarkova M.A., Tskhovrebova L.V., Shutova M.V. Error-prone nonhomologous end joining repair operates in human pluripotent stem cells during late G2. Aging 2011, 3:584-596.
-
(2011)
Aging
, vol.3
, pp. 584-596
-
-
Bogomazova AN, K.S.1
Lagarkova, M.A.2
Tskhovrebova, L.V.3
Shutova, M.V.4
-
87
-
-
33747604117
-
The analysis of mitochondria and mitochondrial DNA in human embryonic stem cells
-
St John J.C., Amaral A., Bowles E., Oliveira J.F., Lloyd R., Freitas M., et al. The analysis of mitochondria and mitochondrial DNA in human embryonic stem cells. Methods Mol. Biol. 2006, 331:347-374.
-
(2006)
Methods Mol. Biol.
, vol.331
, pp. 347-374
-
-
St John, J.C.1
Amaral, A.2
Bowles, E.3
Oliveira, J.F.4
Lloyd, R.5
Freitas, M.6
-
88
-
-
33747875396
-
Dynamic changes in mitochondrial biogenesis and antioxidant enzymes during the spontaneous differentiation of human embryonic stem cells
-
Cho Y.M., Kwon S., Pak Y.K., Seol H.W., Choi Y.M., Park D.J., et al. Dynamic changes in mitochondrial biogenesis and antioxidant enzymes during the spontaneous differentiation of human embryonic stem cells. Biochem. Biophys. Res. Commun. 2006, 348:1472-1478.
-
(2006)
Biochem. Biophys. Res. Commun.
, vol.348
, pp. 1472-1478
-
-
Cho, Y.M.1
Kwon, S.2
Pak, Y.K.3
Seol, H.W.4
Choi, Y.M.5
Park, D.J.6
-
89
-
-
49249086654
-
Coordinated changes of mitochondrial biogenesis and antioxidant enzymes during osteogenic differentiation of human mesenchymal stem cells
-
Chen C.-T., Shih Y.-R.V., Kuo T.K., Lee O.K., Wei Y.-H. Coordinated changes of mitochondrial biogenesis and antioxidant enzymes during osteogenic differentiation of human mesenchymal stem cells. Stem Cells 2008, 26:960-968.
-
(2008)
Stem Cells
, vol.26
, pp. 960-968
-
-
Chen, C.-T.1
Shih, Y.-R.V.2
Kuo, T.K.3
Lee, O.K.4
Wei, Y.-H.5
-
90
-
-
27744563079
-
The expression of mitochondrial DNA transcription factors during early cardiomyocyte in vitro differentiation from human embryonic stem cells
-
St John J.C., Ramalho-Santos J., Gray H.L., Petrosko P., Rawe V.Y., Navara C.S., et al. The expression of mitochondrial DNA transcription factors during early cardiomyocyte in vitro differentiation from human embryonic stem cells. Cloning Stem Cells 2005, 7:141-153.
-
(2005)
Cloning Stem Cells
, vol.7
, pp. 141-153
-
-
St John, J.C.1
Ramalho-Santos, J.2
Gray, H.L.3
Petrosko, P.4
Rawe, V.Y.5
Navara, C.S.6
-
91
-
-
33744908287
-
Differentiation-related changes in mitochondrial properties as indicators of stem cell competence
-
Lonergan T., Brenner C., Bavister B. Differentiation-related changes in mitochondrial properties as indicators of stem cell competence. J. Cell. Physiol. 2006, 208:149-153.
-
(2006)
J. Cell. Physiol.
, vol.208
, pp. 149-153
-
-
Lonergan, T.1
Brenner, C.2
Bavister, B.3
-
92
-
-
40949088547
-
Downregulation of multiple stress defense mechanisms during differentiation of human embryonic stem cells
-
Saretzki G., Walter T., Atkinson S., Passos J.F., Bareth B., Keith W.N., et al. Downregulation of multiple stress defense mechanisms during differentiation of human embryonic stem cells. Stem Cells 2008, 26:455-464.
-
(2008)
Stem Cells
, vol.26
, pp. 455-464
-
-
Saretzki, G.1
Walter, T.2
Atkinson, S.3
Passos, J.F.4
Bareth, B.5
Keith, W.N.6
-
93
-
-
33750524413
-
Self-renewal of human embryonic stem cells is supported by a shortened G1 cell cycle phase
-
Becker K.A., Ghule P.N., Therrien J.A., Lian J.B., Stein J.L., van Wijnen A.J., et al. Self-renewal of human embryonic stem cells is supported by a shortened G1 cell cycle phase. J. Cell. Physiol. 2006, 209:883-893.
-
(2006)
J. Cell. Physiol.
, vol.209
, pp. 883-893
-
-
Becker, K.A.1
Ghule, P.N.2
Therrien, J.A.3
Lian, J.B.4
Stein, J.L.5
van Wijnen, A.J.6
-
94
-
-
77249176666
-
P53 and stem cells: new developments and new concerns
-
Zhao T., Xu Y. p53 and stem cells: new developments and new concerns. Trends Cell Biol. 2010, 20:170-175.
-
(2010)
Trends Cell Biol.
, vol.20
, pp. 170-175
-
-
Zhao, T.1
Xu, Y.2
-
95
-
-
13944273471
-
P53 induces differentiation of mouse embryonic stem cells by suppressing Nanog expression
-
Lin T., Chao C., Saito S., Mazur S.J., Murphy M.E., Appella E., et al. p53 induces differentiation of mouse embryonic stem cells by suppressing Nanog expression. Nat. Cell Biol. 2005, 7:165-171.
-
(2005)
Nat. Cell Biol.
, vol.7
, pp. 165-171
-
-
Lin, T.1
Chao, C.2
Saito, S.3
Mazur, S.J.4
Murphy, M.E.5
Appella, E.6
-
96
-
-
36248966518
-
Induction of pluripotent stem cells from adult human fibroblasts by defined factors
-
Takahashi K., Tanabe K., Ohnuki M., Narita M., Ichisaka T., Tomoda K., et al. Induction of pluripotent stem cells from adult human fibroblasts by defined factors. Cell 2007, 131:861-872.
-
(2007)
Cell
, vol.131
, pp. 861-872
-
-
Takahashi, K.1
Tanabe, K.2
Ohnuki, M.3
Narita, M.4
Ichisaka, T.5
Tomoda, K.6
-
97
-
-
56049091987
-
Modeling epilepsy with pluripotent human cells
-
Muotri A.R. Modeling epilepsy with pluripotent human cells. Epilepsy Behav. 2009, 14(Suppl. 1):81-85.
-
(2009)
Epilepsy Behav.
, vol.14
, Issue.SUPPL. 1
, pp. 81-85
-
-
Muotri, A.R.1
-
98
-
-
77953879152
-
Pluripotent stem cells in neurodegenerative and neurodevelopmental diseases
-
Marchetto M.C.N., Winner B., Gage F.H. Pluripotent stem cells in neurodegenerative and neurodevelopmental diseases. Hum. Mol. Genet. 2010, 19:R71-R76.
-
(2010)
Hum. Mol. Genet.
, vol.19
-
-
Marchetto, M.C.N.1
Winner, B.2
Gage, F.H.3
-
99
-
-
77951021307
-
Human induced pluripotent stem cell lines show stress defense mechanisms and mitochondrial regulation similar to those of human embryonic stem cells
-
Armstrong L., Tilgner K., Saretzki G., Atkinson S.P., Stojkovic M., Moreno R., et al. Human induced pluripotent stem cell lines show stress defense mechanisms and mitochondrial regulation similar to those of human embryonic stem cells. Stem Cells 2010, 28:661-673.
-
(2010)
Stem Cells
, vol.28
, pp. 661-673
-
-
Armstrong, L.1
Tilgner, K.2
Saretzki, G.3
Atkinson, S.P.4
Stojkovic, M.5
Moreno, R.6
-
100
-
-
79960274488
-
Human induced pluripotent cells resemble embryonic stem cells demonstrating enhanced levels of DNA repair and efficacy of nonhomologous end-joining
-
Fan J., Robert C., Jang Y.-Y., Liu H., Sharkis S., Baylin S.B., et al. Human induced pluripotent cells resemble embryonic stem cells demonstrating enhanced levels of DNA repair and efficacy of nonhomologous end-joining. Mutat. Res. 2011, 713:8-17.
-
(2011)
Mutat. Res.
, vol.713
, pp. 8-17
-
-
Fan, J.1
Robert, C.2
Jang, Y.-Y.3
Liu, H.4
Sharkis, S.5
Baylin, S.B.6
-
101
-
-
69249126660
-
Ionizing radiation induces ataxia telangiectasia mutated-dependent checkpoint signaling and G(2) but not G(1) cell cycle arrest in pluripotent human embryonic stem cells
-
Momcilović O., Choi S., Varum S., Bakkenist C., Schatten G., Navara C. Ionizing radiation induces ataxia telangiectasia mutated-dependent checkpoint signaling and G(2) but not G(1) cell cycle arrest in pluripotent human embryonic stem cells. Stem Cells 2009, 27:1822-1835.
-
(2009)
Stem Cells
, vol.27
, pp. 1822-1835
-
-
Momcilović, O.1
Choi, S.2
Varum, S.3
Bakkenist, C.4
Schatten, G.5
Navara, C.6
-
102
-
-
79952258224
-
Somatic coding mutations in human induced pluripotent stem cells
-
Gore A., Li Z., Fung H.-L., Young J.E., Agarwal S., Antosiewicz-Bourget J., et al. Somatic coding mutations in human induced pluripotent stem cells. Nature 2011, 471:63-67.
-
(2011)
Nature
, vol.471
, pp. 63-67
-
-
Gore, A.1
Li, Z.2
Fung, H.-L.3
Young, J.E.4
Agarwal, S.5
Antosiewicz-Bourget, J.6
-
103
-
-
79952264847
-
Hotspots of aberrant epigenomic reprogramming in human induced pluripotent stem cells
-
Lister R., Pelizzola M., Kida Y.S., Hawkins R.D., Nery J.R., Hon G., et al. Hotspots of aberrant epigenomic reprogramming in human induced pluripotent stem cells. Nature 2011, 471:68-73.
-
(2011)
Nature
, vol.471
, pp. 68-73
-
-
Lister, R.1
Pelizzola, M.2
Kida, Y.S.3
Hawkins, R.D.4
Nery, J.R.5
Hon, G.6
-
104
-
-
84863243911
-
DNA repair in human pluripotent stem cells is distinct from that in non-pluripotent human cells
-
Luo L.Z., Gopalakrishna-Pillai S., Nay S.L., Park S.-W., Bates S.E., Zeng X., et al. DNA repair in human pluripotent stem cells is distinct from that in non-pluripotent human cells. PLoS ONE 2012, 7:e30541.
-
(2012)
PLoS ONE
, vol.7
-
-
Luo, L.Z.1
Gopalakrishna-Pillai, S.2
Nay, S.L.3
Park, S.-W.4
Bates, S.E.5
Zeng, X.6
-
105
-
-
79953058250
-
The tumorigenicity of human embryonic and induced pluripotent stem cells
-
Ben-David U., Benvenisty N. The tumorigenicity of human embryonic and induced pluripotent stem cells. Nat. Rev. Cancer 2011, 11:268-277.
-
(2011)
Nat. Rev. Cancer
, vol.11
, pp. 268-277
-
-
Ben-David, U.1
Benvenisty, N.2
-
106
-
-
77958133875
-
Human induced pluripotent stem cells develop teratoma more efficiently and faster than human embryonic stem cells regardless the site of injection
-
Gutierrez-Aranda I., Ramos-Mejia V., Bueno C., Munoz-Lopez M., Real P.J., Mácia A., et al. Human induced pluripotent stem cells develop teratoma more efficiently and faster than human embryonic stem cells regardless the site of injection. Stem Cells 2010, 28:1568-1570.
-
(2010)
Stem Cells
, vol.28
, pp. 1568-1570
-
-
Gutierrez-Aranda, I.1
Ramos-Mejia, V.2
Bueno, C.3
Munoz-Lopez, M.4
Real, P.J.5
Mácia, A.6
-
107
-
-
77957365009
-
Cancer-related epigenome changes associated with reprogramming to induced pluripotent stem cells
-
Ohm J.E., Mali P., Van Neste L., Berman D.M., Liang L., Pandiyan K., et al. Cancer-related epigenome changes associated with reprogramming to induced pluripotent stem cells. Cancer Res. 2010, 70(19):7662-7673.
-
(2010)
Cancer Res.
, vol.70
, Issue.19
, pp. 7662-7673
-
-
Ohm, J.E.1
Mali, P.2
Van Neste, L.3
Berman, D.M.4
Liang, L.5
Pandiyan, K.6
-
108
-
-
68249087053
-
Variation in the safety of induced pluripotent stem cell lines
-
Miura K., Okada Y., Aoi T., Okada A., Takahashi K., Okita K., et al. Variation in the safety of induced pluripotent stem cell lines. Nat. Biotechnol. 2009, 27:743-745.
-
(2009)
Nat. Biotechnol.
, vol.27
, pp. 743-745
-
-
Miura, K.1
Okada, Y.2
Aoi, T.3
Okada, A.4
Takahashi, K.5
Okita, K.6
-
109
-
-
78149488365
-
A model for neural development and treatment of Rett syndrome using human induced pluripotent stem cells
-
Marchetto M.C.N., Carromeu C., Acab A., Yu D., Yeo G.W., Mu Y., et al. A model for neural development and treatment of Rett syndrome using human induced pluripotent stem cells. Cell 2010, 143:527-539.
-
(2010)
Cell
, vol.143
, pp. 527-539
-
-
Marchetto, M.C.N.1
Carromeu, C.2
Acab, A.3
Yu, D.4
Yeo, G.W.5
Mu, Y.6
-
110
-
-
79956106682
-
From skin to the treatment of diseases-the possibilities of iPS cell research in dermatology
-
Galach M., Utikal J. From skin to the treatment of diseases-the possibilities of iPS cell research in dermatology. Exp. Dermatol. 2011, 20:523-528.
-
(2011)
Exp. Dermatol.
, vol.20
, pp. 523-528
-
-
Galach, M.1
Utikal, J.2
-
111
-
-
54949136146
-
Two supporting factors greatly improve the efficiency of human iPSC generation
-
Zhao Y., Yin X., Qin H., Zhu F., Liu H., Yang W., et al. Two supporting factors greatly improve the efficiency of human iPSC generation. Cell Stem Cell. 2008, 3:475-479.
-
(2008)
Cell Stem Cell.
, vol.3
, pp. 475-479
-
-
Zhao, Y.1
Yin, X.2
Qin, H.3
Zhu, F.4
Liu, H.5
Yang, W.6
-
112
-
-
69349100179
-
Suppression of induced pluripotent stem cell generation by the p53-p21 pathway
-
Hong H., Takahashi K., Ichisaka T., Aoi T., Kanagawa O., Nakagawa M., et al. Suppression of induced pluripotent stem cell generation by the p53-p21 pathway. Nature 2009, 460:1132-1135.
-
(2009)
Nature
, vol.460
, pp. 1132-1135
-
-
Hong, H.1
Takahashi, K.2
Ichisaka, T.3
Aoi, T.4
Kanagawa, O.5
Nakagawa, M.6
-
113
-
-
69349094006
-
A p53-mediated DNA damage response limits reprogramming to ensure iPS cell genomic integrity
-
Marion R.M., Strati K., Li H., Murga M., Blanco R., Ortega S., et al. A p53-mediated DNA damage response limits reprogramming to ensure iPS cell genomic integrity. Nature 2009, 460:1149-1153.
-
(2009)
Nature
, vol.460
, pp. 1149-1153
-
-
Marion, R.M.1
Strati, K.2
Li, H.3
Murga, M.4
Blanco, R.5
Ortega, S.6
-
114
-
-
38049028459
-
Generation of induced pluripotent stem cells without Myc from mouse and human fibroblasts
-
Nakagawa M., Koyanagi M., Tanabe K., Takahashi K., Ichisaka T., Aoi T., et al. Generation of induced pluripotent stem cells without Myc from mouse and human fibroblasts. Nat. Biotechnol. 2008, 26:101-106.
-
(2008)
Nat. Biotechnol.
, vol.26
, pp. 101-106
-
-
Nakagawa, M.1
Koyanagi, M.2
Tanabe, K.3
Takahashi, K.4
Ichisaka, T.5
Aoi, T.6
-
115
-
-
37549008674
-
C-Myc is dispensable for direct reprogramming of mouse fibroblasts
-
Wernig M., Meissner A., Cassady J.P., Jaenisch R. c-Myc is dispensable for direct reprogramming of mouse fibroblasts. Cell Stem Cell. 2008, 2:10-12.
-
(2008)
Cell Stem Cell.
, vol.2
, pp. 10-12
-
-
Wernig, M.1
Meissner, A.2
Cassady, J.P.3
Jaenisch, R.4
-
116
-
-
79960219150
-
Advancements in reprogramming strategies for the generation of induced pluripotent stem cells
-
Lai M.I., Wendy-Yeo W.Y., Ramasamy R., Nordin N., Rosli R., Veerakumarasivam A., et al. Advancements in reprogramming strategies for the generation of induced pluripotent stem cells. J. Assist. Reprod. Genet. 2011, 28:291-301.
-
(2011)
J. Assist. Reprod. Genet.
, vol.28
, pp. 291-301
-
-
Lai, M.I.1
Wendy-Yeo, W.Y.2
Ramasamy, R.3
Nordin, N.4
Rosli, R.5
Veerakumarasivam, A.6
-
117
-
-
39149115929
-
Defining molecular cornerstones during fibroblast to iPS cell reprogramming in mouse
-
Stadtfeld M., Maherali N., Breault D.T., Hochedlinger K. Defining molecular cornerstones during fibroblast to iPS cell reprogramming in mouse. Cell Stem Cell. 2008, 2:230-240.
-
(2008)
Cell Stem Cell.
, vol.2
, pp. 230-240
-
-
Stadtfeld, M.1
Maherali, N.2
Breault, D.T.3
Hochedlinger, K.4
-
118
-
-
77955449906
-
Epigenetic memory in induced pluripotent stem cells
-
Kim K., Doi A., Wen B., Ng K., Zhao R., Cahan P., et al. Epigenetic memory in induced pluripotent stem cells. Nature 2010, 467:285-290.
-
(2010)
Nature
, vol.467
, pp. 285-290
-
-
Kim, K.1
Doi, A.2
Wen, B.3
Ng, K.4
Zhao, R.5
Cahan, P.6
-
119
-
-
55749104227
-
Induction of pluripotent stem cells from primary human fibroblasts with only Oct4 and Sox2
-
Huangfu D., Osafune K., Maehr R., Guo W., Eijkelenboom A., Chen S., et al. Induction of pluripotent stem cells from primary human fibroblasts with only Oct4 and Sox2. Nat. Biotechnol. 2008, 26:1269-1275.
-
(2008)
Nat. Biotechnol.
, vol.26
, pp. 1269-1275
-
-
Huangfu, D.1
Osafune, K.2
Maehr, R.3
Guo, W.4
Eijkelenboom, A.5
Chen, S.6
-
120
-
-
65249149666
-
Induced pluripotent stem cell generation using a single lentiviral stem cell cassette
-
Sommer C.A., Stadtfeld M., Murphy G.J., Hochedlinger K., Kotton D.N., Mostoslavsky G. Induced pluripotent stem cell generation using a single lentiviral stem cell cassette. Stem Cells 2009, 27:543-549.
-
(2009)
Stem Cells
, vol.27
, pp. 543-549
-
-
Sommer, C.A.1
Stadtfeld, M.2
Murphy, G.J.3
Hochedlinger, K.4
Kotton, D.N.5
Mostoslavsky, G.6
-
121
-
-
77953466536
-
Nuclear reprogramming to a pluripotent state by three approaches
-
Yamanaka S., Blau H.M. Nuclear reprogramming to a pluripotent state by three approaches. Nature 2010, 465:704-712.
-
(2010)
Nature
, vol.465
, pp. 704-712
-
-
Yamanaka, S.1
Blau, H.M.2
-
122
-
-
84859239896
-
DNA repair mechanisms protect our genome from carcinogenesis
-
Moraes M.C.S., Neto J.B.C., Menck C.F.M. DNA repair mechanisms protect our genome from carcinogenesis. Front. Biosci. 2012, 17:1362-1388.
-
(2012)
Front. Biosci.
, vol.17
, pp. 1362-1388
-
-
Moraes, M.C.S.1
Neto, J.B.C.2
Menck, C.F.M.3
-
123
-
-
84930539170
-
Xeroderma pigmentosum: living in the dark but with hope in therapy
-
Lima-Bessa K.M., Soltys D.T., Marchetto M.C., Menck C.F.M. Xeroderma pigmentosum: living in the dark but with hope in therapy. Drug Future 2009, 34:665-672.
-
(2009)
Drug Future
, vol.34
, pp. 665-672
-
-
Lima-Bessa, K.M.1
Soltys, D.T.2
Marchetto, M.C.3
Menck, C.F.M.4
-
124
-
-
21744452376
-
Cancer in Xeroderma pigmentosum and related disorders of DNA repair
-
Cleaver J.E. Cancer in Xeroderma pigmentosum and related disorders of DNA repair. Nat. Rev. Cancer 2005, 5:564-573.
-
(2005)
Nat. Rev. Cancer
, vol.5
, pp. 564-573
-
-
Cleaver, J.E.1
-
125
-
-
84859439249
-
Preclinical corrective gene transfer in xeroderma pigmentosum human skin stem cells
-
Warrick E., Garcia M., Chagnoleau C., Chevallier O., Bergoglio V., Sartori D., et al. Preclinical corrective gene transfer in xeroderma pigmentosum human skin stem cells. Mol. Ther. 2011, 20:798-807.
-
(2011)
Mol. Ther.
, vol.20
, pp. 798-807
-
-
Warrick, E.1
Garcia, M.2
Chagnoleau, C.3
Chevallier, O.4
Bergoglio, V.5
Sartori, D.6
-
126
-
-
79952773623
-
Differentiation of mouse induced pluripotent stem cells into a multipotent keratinocyte lineage
-
Bilousova G., Chen J., Roop D.R. Differentiation of mouse induced pluripotent stem cells into a multipotent keratinocyte lineage. J. Invest. Dermatol. 2011, 131:857-864.
-
(2011)
J. Invest. Dermatol.
, vol.131
, pp. 857-864
-
-
Bilousova, G.1
Chen, J.2
Roop, D.R.3
-
127
-
-
79251578074
-
Generation of human melanocytes from induced pluripotent stem cells
-
Ohta S., Imaizumi Y., Okada Y., Akamatsu W., Kuwahara R., Ohyama M., et al. Generation of human melanocytes from induced pluripotent stem cells. PLoS ONE 2011, 6:e16182.
-
(2011)
PLoS ONE
, vol.6
-
-
Ohta, S.1
Imaizumi, Y.2
Okada, Y.3
Akamatsu, W.4
Kuwahara, R.5
Ohyama, M.6
-
128
-
-
70249114821
-
Efficient targeting of expressed and silent genes in human ESCs and iPSCs using zinc-finger nucleases
-
Hockemeyer D., Soldner F., Beard C., Gao Q., Mitalipova M., DeKelver R.C., et al. Efficient targeting of expressed and silent genes in human ESCs and iPSCs using zinc-finger nucleases. Nat. Biotechnol. 2009, 27:851-857.
-
(2009)
Nat. Biotechnol.
, vol.27
, pp. 851-857
-
-
Hockemeyer, D.1
Soldner, F.2
Beard, C.3
Gao, Q.4
Mitalipova, M.5
DeKelver, R.C.6
-
129
-
-
67650095306
-
Disease-corrected haematopoietic progenitors from Fanconi anaemia induced pluripotent stem cells
-
Raya A., Rodriguez-Piza I., Guenechea G., Vassena R., Navarro S., Barrero M.J., et al. Disease-corrected haematopoietic progenitors from Fanconi anaemia induced pluripotent stem cells. Nature 2009, 460:53-59.
-
(2009)
Nature
, vol.460
, pp. 53-59
-
-
Raya, A.1
Rodriguez-Piza, I.2
Guenechea, G.3
Vassena, R.4
Navarro, S.5
Barrero, M.J.6
-
131
-
-
84861912972
-
Overcoming reprogramming resistance of Fanconi anemia cells
-
Müller L.U.W., Milsom M.D., Harris C.E., Vyas R., Brumme K.M., Parmar K., et al. Overcoming reprogramming resistance of Fanconi anemia cells. Blood 2012, 119:5449-5457.
-
(2012)
Blood
, vol.119
, pp. 5449-5457
-
-
Müller, L.U.W.1
Milsom, M.D.2
Harris, C.E.3
Vyas, R.4
Brumme, K.M.5
Parmar, K.6
-
132
-
-
80053538947
-
A DNA repair complex functions as an Oct4/Sox2 coactivator in embryonic stem cells
-
Fong Y.W., Inouye C., Yamaguchi T., Cattoglio C., Grubisic I., Tjian R. A DNA repair complex functions as an Oct4/Sox2 coactivator in embryonic stem cells. Cell 2011, 147:120-131.
-
(2011)
Cell
, vol.147
, pp. 120-131
-
-
Fong, Y.W.1
Inouye, C.2
Yamaguchi, T.3
Cattoglio, C.4
Grubisic, I.5
Tjian, R.6
-
133
-
-
84865070766
-
Evidence for premature aging due to oxidative stress in iPSCs from Cockayne syndrome
-
Andrade L.N., Nathanson J.L., Yeo G.W., Menck C.F.M., Muotri A.R. Evidence for premature aging due to oxidative stress in iPSCs from Cockayne syndrome. Hum. Mol. Genet. 2012, 21:3825-3834.
-
(2012)
Hum. Mol. Genet.
, vol.21
, pp. 3825-3834
-
-
Andrade, L.N.1
Nathanson, J.L.2
Yeo, G.W.3
Menck, C.F.M.4
Muotri, A.R.5
|