A high-fat diet and NAD+ activate sirt1 to rescue premature aging in cockayne syndrome

Cell Metabolism

Volumn 20, Issue 5, 2014, Pages 840-855

  Scheibye Knudsen, Morten ^a   Mitchell, Sarah J ^a,b   Fang, Evandro F ^a   Iyama, Teruaki ^a   Ward, Theresa ^a   Wang, James ^a   Dunn, Christopher A ^a   Singh, Nagendra ^a   Veith, Sebastian ^c   Hasan Olive, Md Mahdi ^a   Mangerich, Aswin ^c   Wilson, Mark A ^a   Mattson, Mark P ^a   Bergersen, Linda H ^d,f   Cogger, Victoria C ^b,e   Warren, Alessandra ^e   Le Couteur, David G ^b,e   Moaddel, Ruin ^a   Wilson, David M ^a   Croteau, Deborah L ^a   De Cabo, Rafael ^a   Bohr, Vilhelm A ^a,f   more..

^a NATIONAL INSTITUTE ON AGING   (United States)

^b UNIVERSITY OF SYDNEY   (Australia)

^c UNIVERSITY OF KONSTANZ   (Germany)

^d UNIVERSITY OF OSLO   (Norway)

^e UNIVERSITY OF SYDNEY   (Australia)

^f UNIVERSITY OF COPENHAGEN   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

3 HYDROXYBUTYRIC ACID; NICOTINAMIDE ADENINE DINUCLEOTIDE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE 1; RESVERATROL; SIRTUIN 1; PARP1 PROTEIN, MOUSE; SIRT1 PROTEIN, MOUSE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CALORIC RESTRICTION; COCKAYNE SYNDROME; CONTROLLED STUDY; DEGENERATIVE DISEASE; DIET SUPPLEMENTATION; DISORDERS OF MITOCHONDRIAL FUNCTIONS; DNA DAMAGE; DNA REPAIR; ENZYME INHIBITION; GENE MUTATION; LIPID DIET; LONGEVITY; MOUSE; NONHUMAN; PHENOTYPE; PREMATURE AGING; TRANSCRIPTOMICS; AGING, PREMATURE; ANIMAL; C57BL MOUSE; CELL LINE; COMPLICATION; DIET THERAPY; ENZYME ACTIVATION; HUMAN; METABOLISM; MITOCHONDRION; PATHOLOGY;

3-HYDROXYBUTYRIC ACID; AGING, PREMATURE; ANIMALS; CELL LINE; COCKAYNE SYNDROME; DIET, HIGH-FAT; ENZYME ACTIVATION; HUMANS; MICE; MICE, INBRED C57BL; MITOCHONDRIA; NAD; POLY(ADP-RIBOSE) POLYMERASES; SIRTUIN 1;

EID: 84910132320     PISSN: 15504131     EISSN: 19327420     Source Type: Journal    
DOI: 10.1016/j.cmet.2014.10.005     Document Type: Article

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