메뉴 건너뛰기




Volumn 115, Issue C, 2014, Pages 189-209

Proton-sensitive cation channels and ion exchangers in ischemic brain injury: New therapeutic targets for stroke?

Author keywords

Acidosis; ASIC; Calcium; NHE1; TRPM7; Zinc

Indexed keywords

ACID SENSING ION CHANNEL; CALCIUM; CATION TRANSPORT PROTEIN; SLC9A1 PROTEIN, HUMAN; SODIUM PROTON EXCHANGE PROTEIN; TRANSIENT RECEPTOR POTENTIAL CHANNEL M; TRPM2 PROTEIN, HUMAN; ZINC;

EID: 84908373385     PISSN: 03010082     EISSN: 18735118     Source Type: Journal    
DOI: 10.1016/j.pneurobio.2013.12.008     Document Type: Review
Times cited : (102)

References (357)
  • 2
    • 79954421653 scopus 로고    scopus 로고
    • Role of melastatin transient receptor potential 7 channels in the osteoblastic differentiation of murine MC3T3 cells
    • Abed E., Martineau C., Moreau R. Role of melastatin transient receptor potential 7 channels in the osteoblastic differentiation of murine MC3T3 cells. Calcif Tissue Int. 2011, 88:246-253.
    • (2011) Calcif Tissue Int. , vol.88 , pp. 246-253
    • Abed, E.1    Martineau, C.2    Moreau, R.3
  • 3
    • 36248933061 scopus 로고    scopus 로고
    • Importance of melastatin-like transient receptor potential 7 and cations (magnesium, calcium) in human osteoblast-like cell proliferation
    • Abed E., Moreau R. Importance of melastatin-like transient receptor potential 7 and cations (magnesium, calcium) in human osteoblast-like cell proliferation. Cell Prolif. 2007, 40:849-865.
    • (2007) Cell Prolif. , vol.40 , pp. 849-865
    • Abed, E.1    Moreau, R.2
  • 4
    • 68849131636 scopus 로고    scopus 로고
    • Importance of melastatin-like transient receptor potential 7 and magnesium in the stimulation of osteoblast proliferation and migration by platelet-derived growth factor
    • Abed E., Moreau R. Importance of melastatin-like transient receptor potential 7 and magnesium in the stimulation of osteoblast proliferation and migration by platelet-derived growth factor. Am. J. Physiol. Cell Physiol. 2009, 297:C360-C368.
    • (2009) Am. J. Physiol. Cell Physiol. , vol.297 , pp. C360-C368
    • Abed, E.1    Moreau, R.2
  • 6
    • 84873116858 scopus 로고    scopus 로고
    • Ischemic stroke and traumatic brain injury: the role of the kallikrein-kinin system
    • Albert-Weissenberger C., Siren A.L., Kleinschnitz C. Ischemic stroke and traumatic brain injury: the role of the kallikrein-kinin system. Prog. Neurobiol. 2013, 101/102:65-82.
    • (2013) Prog. Neurobiol. , pp. 65-82
    • Albert-Weissenberger, C.1    Siren, A.L.2    Kleinschnitz, C.3
  • 7
    • 0036711958 scopus 로고    scopus 로고
    • Modulation of ASIC channels in rat cerebellar Purkinje neurons by ischaemia-related signals
    • Allen N.J., Attwell D. Modulation of ASIC channels in rat cerebellar Purkinje neurons by ischaemia-related signals. J. Physiol. 2002, 543:521-529.
    • (2002) J. Physiol. , vol.543 , pp. 521-529
    • Allen, N.J.1    Attwell, D.2
  • 8
    • 0033858350 scopus 로고    scopus 로고
    • Structure and regulation of amiloride-sensitive sodium channels
    • Alvarez d.l.R., Canessa C.M., Fyfe G.K., Zhang P. Structure and regulation of amiloride-sensitive sodium channels. Annu. Rev. Physiol. 2000, 62:573-594.
    • (2000) Annu. Rev. Physiol. , vol.62 , pp. 573-594
    • Alvarez, D.1    Canessa, C.M.2    Fyfe, G.K.3    Zhang, P.4
  • 10
    • 0019975497 scopus 로고
    • + exchanger in renal microvillus membrane vesicles
    • + exchanger in renal microvillus membrane vesicles. Nature 1982, 299:161-163.
    • (1982) Nature , vol.299 , pp. 161-163
    • Aronson, P.S.1    Nee, J.2    Suhm, M.A.3
  • 11
    • 0033695107 scopus 로고    scopus 로고
    • Neuropeptide FF and FMRFamide potentiate acid-evoked currents from sensory neurons and proton-gated DEG/ENaC channels
    • Askwith C.C., Cheng C., Ikuma M., Benson C., Price M.P., Welsh M.J. Neuropeptide FF and FMRFamide potentiate acid-evoked currents from sensory neurons and proton-gated DEG/ENaC channels. Neuron 2000, 26:133-141.
    • (2000) Neuron , vol.26 , pp. 133-141
    • Askwith, C.C.1    Cheng, C.2    Ikuma, M.3    Benson, C.4    Price, M.P.5    Welsh, M.J.6
  • 13
    • 0034919120 scopus 로고    scopus 로고
    • + exchange inhibitors: potential mechanisms of action
    • + exchange inhibitors: potential mechanisms of action. Basic Res. Cardiol. 2001, 96:306-311.
    • (2001) Basic Res. Cardiol. , vol.96 , pp. 306-311
    • Avkiran, M.1
  • 14
    • 0036828828 scopus 로고    scopus 로고
    • Alternative splicing and interaction with di- and polyvalent cations control the dynamic range of acid-sensing ion channel 1 (ASIC1)
    • Babini E., Paukert M., Geisler H.S., Grunder S. Alternative splicing and interaction with di- and polyvalent cations control the dynamic range of acid-sensing ion channel 1 (ASIC1). J. Biol. Chem. 2002, 277:41597-41603.
    • (2002) J. Biol. Chem. , vol.277 , pp. 41597-41603
    • Babini, E.1    Paukert, M.2    Geisler, H.S.3    Grunder, S.4
  • 16
    • 0032900533 scopus 로고    scopus 로고
    • Molecular cloning and regional distribution of a human proton receptor subunit with biphasic functional properties
    • Babinski K., Le K.T., Seguela P. Molecular cloning and regional distribution of a human proton receptor subunit with biphasic functional properties. J. Neurochem. 1999, 72:51-57.
    • (1999) J. Neurochem. , vol.72 , pp. 51-57
    • Babinski, K.1    Le, K.T.2    Seguela, P.3
  • 17
    • 0035866062 scopus 로고    scopus 로고
    • Late oligodendrocyte progenitors coincide with the developmental window of vulnerability for human perinatal white matter injury
    • Back S.A., Luo N.L., Borenstein N.S., Levine J.M., Volpe J.J., Kinney H.C. Late oligodendrocyte progenitors coincide with the developmental window of vulnerability for human perinatal white matter injury. J. Neurosci. 2001, 21:1302-1312.
    • (2001) J. Neurosci. , vol.21 , pp. 1302-1312
    • Back, S.A.1    Luo, N.L.2    Borenstein, N.S.3    Levine, J.M.4    Volpe, J.J.5    Kinney, H.C.6
  • 18
    • 84875339438 scopus 로고    scopus 로고
    • Regulation and function of TRPM7 in human endothelial cells: TRPM7 as a potential novel regulator of endothelial function
    • Baldoli E., Castiglioni S., Maier J.A. Regulation and function of TRPM7 in human endothelial cells: TRPM7 as a potential novel regulator of endothelial function. PLoS ONE 2013, 8:e59891.
    • (2013) PLoS ONE , vol.8
    • Baldoli, E.1    Castiglioni, S.2    Maier, J.A.3
  • 20
    • 38949113205 scopus 로고    scopus 로고
    • Acid sensing ion channels in dorsal spinal cord neurons
    • Baron A., Voilley N., Lazdunski M., Lingueglia E. Acid sensing ion channels in dorsal spinal cord neurons. J. Neurosci. 2008, 28:1498-1508.
    • (2008) J. Neurosci. , vol.28 , pp. 1498-1508
    • Baron, A.1    Voilley, N.2    Lazdunski, M.3    Lingueglia, E.4
  • 23
    • 33846794822 scopus 로고    scopus 로고
    • The NOX family of ROS-generating NADPH oxidases: physiology and pathophysiology
    • Bedard K., Krause K.H. The NOX family of ROS-generating NADPH oxidases: physiology and pathophysiology. Physiol. Rev. 2007, 87:245-313.
    • (2007) Physiol. Rev. , vol.87 , pp. 245-313
    • Bedard, K.1    Krause, K.H.2
  • 24
    • 0033617361 scopus 로고    scopus 로고
    • Acid-evoked currents in cardiac sensory neurons: a possible mediator of myocardial ischemic sensation
    • Benson C.J., Eckert S.P., McCleskey E.W. Acid-evoked currents in cardiac sensory neurons: a possible mediator of myocardial ischemic sensation. Circ. Res. 1999, 84:921-928.
    • (1999) Circ. Res. , vol.84 , pp. 921-928
    • Benson, C.J.1    Eckert, S.P.2    McCleskey, E.W.3
  • 26
    • 0021707433 scopus 로고
    • Elevation of the extracellular concentrations of glutamate and aspartate in rat hippocampus during transient cerebral ischemia monitored by intracerebral microdialysis
    • Benveniste H., Drejer J., Schousboe A., Diemer N.H. Elevation of the extracellular concentrations of glutamate and aspartate in rat hippocampus during transient cerebral ischemia monitored by intracerebral microdialysis. J. Neurochem. 1984, 43:1369-1374.
    • (1984) J. Neurochem. , vol.43 , pp. 1369-1374
    • Benveniste, H.1    Drejer, J.2    Schousboe, A.3    Diemer, N.H.4
  • 27
    • 11344294298 scopus 로고    scopus 로고
    • Limiting stroke-induced damage by targeting an acid channel
    • Benveniste M., Dingledine R. Limiting stroke-induced damage by targeting an acid channel. N. Engl. J. Med. 2005, 352:85-86.
    • (2005) N. Engl. J. Med. , vol.352 , pp. 85-86
    • Benveniste, M.1    Dingledine, R.2
  • 29
    • 0036939246 scopus 로고    scopus 로고
    • CD14 expression by activated parenchymal microglia/macrophages and infiltrating monocytes following human traumatic brain injury
    • Beschorner R., Nguyen T.D., Gozalan F., Pedal I., Mattern R., Schluesener H.J., Meyermann R., Schwab J.M. CD14 expression by activated parenchymal microglia/macrophages and infiltrating monocytes following human traumatic brain injury. Acta Neuropathol. 2002, 103(6):541-549.
    • (2002) Acta Neuropathol. , vol.103 , Issue.6 , pp. 541-549
    • Beschorner, R.1    Nguyen, T.D.2    Gozalan, F.3    Pedal, I.4    Mattern, R.5    Schluesener, H.J.6    Meyermann, R.7    Schwab, J.M.8
  • 30
    • 32044443148 scopus 로고    scopus 로고
    • Protection of endothelial-derived vasorelaxation with cariporide, a sodium-proton exchanger inhibitor, after prolonged hypoxia and hypoxia-reoxygenation: effect of age
    • Besse S., Tanguy S., Boucher F., Huraux C., Riou B., Swynghedauw B., de Leiris J. Protection of endothelial-derived vasorelaxation with cariporide, a sodium-proton exchanger inhibitor, after prolonged hypoxia and hypoxia-reoxygenation: effect of age. Eur. J. Pharmacol. 2006, 531:187-193.
    • (2006) Eur. J. Pharmacol. , vol.531 , pp. 187-193
    • Besse, S.1    Tanguy, S.2    Boucher, F.3    Huraux, C.4    Riou, B.5    Swynghedauw, B.6    de Leiris, J.7
  • 31
    • 0035109992 scopus 로고    scopus 로고
    • Regional and subunit-specific downregulation of acid-sensing ion channels in the pilocarpine model of epilepsy
    • Biagini G., Babinski K., Avoli M., Marcinkiewicz M., Seguela P. Regional and subunit-specific downregulation of acid-sensing ion channels in the pilocarpine model of epilepsy. Neurobiol. Dis. 2001, 8:45-58.
    • (2001) Neurobiol. Dis. , vol.8 , pp. 45-58
    • Biagini, G.1    Babinski, K.2    Avoli, M.3    Marcinkiewicz, M.4    Seguela, P.5
  • 34
    • 0026702955 scopus 로고
    • Microglial-produced nitric oxide and reactive nitrogen oxides mediate neuronal cell death
    • Boje K.M., Arora P.K. Microglial-produced nitric oxide and reactive nitrogen oxides mediate neuronal cell death. Brain Res. 1992, 587:250-256.
    • (1992) Brain Res. , vol.587 , pp. 250-256
    • Boje, K.M.1    Arora, P.K.2
  • 35
    • 0343060358 scopus 로고    scopus 로고
    • Roles of nitric oxide in brain hypoxia-ischemia
    • Bolanos J.P., Almeida A. Roles of nitric oxide in brain hypoxia-ischemia. Biochim. Biophys. Acta 1999, 1411:415-436.
    • (1999) Biochim. Biophys. Acta , vol.1411 , pp. 415-436
    • Bolanos, J.P.1    Almeida, A.2
  • 36
    • 0042856663 scopus 로고    scopus 로고
    • Impact of sodium-hydrogen exchange inhibition by cariporide on death or myocardial infarction in high-risk CABG surgery patients: results of the CABG surgery cohort of the GUARDIAN study
    • Boyce S.W., Bartels C., Bolli R., Chaitman B., Chen J.C., Chi E., Jessel A., Kereiakes D., Knight J., Thulin L., Theroux P. Impact of sodium-hydrogen exchange inhibition by cariporide on death or myocardial infarction in high-risk CABG surgery patients: results of the CABG surgery cohort of the GUARDIAN study. J. Thorac. Cardiovasc. Surg. 2003, 126:420-427.
    • (2003) J. Thorac. Cardiovasc. Surg. , vol.126 , pp. 420-427
    • Boyce, S.W.1    Bartels, C.2    Bolli, R.3    Chaitman, B.4    Chen, J.C.5    Chi, E.6    Jessel, A.7    Kereiakes, D.8    Knight, J.9    Thulin, L.10    Theroux, P.11
  • 38
    • 0036083415 scopus 로고    scopus 로고
    • + exchanger isoform 6 is found in recycling endosomes of cells, not in mitochondria
    • + exchanger isoform 6 is found in recycling endosomes of cells, not in mitochondria. Am. J. Physiol. Cell Physiol. 2002, 282:C1031-C1041.
    • (2002) Am. J. Physiol. Cell Physiol. , vol.282 , pp. C1031-C1041
    • Brett, C.L.1    Wei, Y.2    Donowitz, M.3    Rao, R.4
  • 40
  • 41
    • 13444278829 scopus 로고    scopus 로고
    • Chemokine receptors in the central nervous system: role in brain inflammation and neurodegenerative diseases
    • Cartier L., Hartley O., Dubois-Dauphin M., Krause K.H. Chemokine receptors in the central nervous system: role in brain inflammation and neurodegenerative diseases. Brain Res. Brain Res. Rev. 2005, 48(1):16-42.
    • (2005) Brain Res. Brain Res. Rev. , vol.48 , Issue.1 , pp. 16-42
    • Cartier, L.1    Hartley, O.2    Dubois-Dauphin, M.3    Krause, K.H.4
  • 44
    • 23644461777 scopus 로고    scopus 로고
    • Solution structure of APETx2, a specific peptide inhibitor of ASIC3 proton-gated channels
    • Chagot B., Escoubas P., Diochot S., Bernard C., Lazdunski M., Darbon H. Solution structure of APETx2, a specific peptide inhibitor of ASIC3 proton-gated channels. Protein Sci. 2005, 14:2003-2010.
    • (2005) Protein Sci. , vol.14 , pp. 2003-2010
    • Chagot, B.1    Escoubas, P.2    Diochot, S.3    Bernard, C.4    Lazdunski, M.5    Darbon, H.6
  • 47
    • 77952958037 scopus 로고    scopus 로고
    • TRPM7 regulates the migration of human nasopharyngeal carcinoma cell by mediating Ca(2+) influx
    • Chen J.P., Luan Y., You C.X., Chen X.H., Luo R.C., Li R. TRPM7 regulates the migration of human nasopharyngeal carcinoma cell by mediating Ca(2+) influx. Cell Calcium 2010, 47:425-432.
    • (2010) Cell Calcium , vol.47 , pp. 425-432
    • Chen, J.P.1    Luan, Y.2    You, C.X.3    Chen, X.H.4    Luo, R.C.5    Li, R.6
  • 48
    • 84891506408 scopus 로고    scopus 로고
    • TRPM7 channels regulate proliferation and adipogenesis in 3T3-L1 preadipocytes
    • Chen K.H., Xu X.H., Liu Y., Hu Y., Jin M.W., Li G.R. TRPM7 channels regulate proliferation and adipogenesis in 3T3-L1 preadipocytes. J. Cell. Physiol. 2014, 229:60-67.
    • (2014) J. Cell. Physiol. , vol.229 , pp. 60-67
    • Chen, K.H.1    Xu, X.H.2    Liu, Y.3    Hu, Y.4    Jin, M.W.5    Li, G.R.6
  • 52
    • 0025320647 scopus 로고
    • The regulation and modulation of pH in the nervous system
    • Chesler M. The regulation and modulation of pH in the nervous system. Prog. Neurobiol. 1990, 34:401-427.
    • (1990) Prog. Neurobiol. , vol.34 , pp. 401-427
    • Chesler, M.1
  • 53
    • 0141863313 scopus 로고    scopus 로고
    • Regulation and modulation of pH in the brain
    • Chesler M. Regulation and modulation of pH in the brain. Physiol. Rev. 2003, 83:1183-1221.
    • (2003) Physiol. Rev. , vol.83 , pp. 1183-1221
    • Chesler, M.1
  • 54
    • 0026705552 scopus 로고
    • Modulation of pH by neuronal activity
    • Chesler M., Kaila K. Modulation of pH by neuronal activity. Trends Neurosci. 1992, 15:396-402.
    • (1992) Trends Neurosci. , vol.15 , pp. 396-402
    • Chesler, M.1    Kaila, K.2
  • 55
    • 34447507908 scopus 로고    scopus 로고
    • Potentiation of acid-sensing ion channels by sulfhydryl compounds
    • Cho J.H., Askwith C.C. Potentiation of acid-sensing ion channels by sulfhydryl compounds. Am. J. Physiol. Cell Physiol. 2007, 292:C2161-C2174.
    • (2007) Am. J. Physiol. Cell Physiol. , vol.292 , pp. C2161-C2174
    • Cho, J.H.1    Askwith, C.C.2
  • 56
    • 0024093449 scopus 로고
    • Glutamate neurotoxicity and diseases of the nervous system
    • Choi D.W. Glutamate neurotoxicity and diseases of the nervous system. Neuron 1988, 1:623-634.
    • (1988) Neuron , vol.1 , pp. 623-634
    • Choi, D.W.1
  • 57
    • 0026497926 scopus 로고
    • Excitotoxic cell death
    • Choi D.W. Excitotoxic cell death. J. Neurobiol. 1992, 23:1261-1276.
    • (1992) J. Neurobiol. , vol.23 , pp. 1261-1276
    • Choi, D.W.1
  • 59
    • 33744981629 scopus 로고    scopus 로고
    • ASIC1a-specific modulation of acid-sensing ion channels in mouse cortical neurons by redox reagents
    • Chu X.P., Close N., Saugstad J.A., Xiong Z.G. ASIC1a-specific modulation of acid-sensing ion channels in mouse cortical neurons by redox reagents. J. Neurosci. 2006, 26:5329-5339.
    • (2006) J. Neurosci. , vol.26 , pp. 5329-5339
    • Chu, X.P.1    Close, N.2    Saugstad, J.A.3    Xiong, Z.G.4
  • 62
    • 84873591578 scopus 로고    scopus 로고
    • Acid-sensing ion channels in pathological conditions
    • Chu X.P., Xiong Z.G. Acid-sensing ion channels in pathological conditions. Adv. Exp. Med. Biol. 2013, 961:419-431.
    • (2013) Adv. Exp. Med. Biol. , vol.961 , pp. 419-431
    • Chu, X.P.1    Xiong, Z.G.2
  • 63
    • 84861302968 scopus 로고    scopus 로고
    • Natural and synthetic modulators of SK (K(ca)2) potassium channels inhibit magnesium-dependent activity of the kinase-coupled cation channel TRPM7
    • Chubanov V., Schnitzler M., Meissner M., Schafer S., Abstiens K., Hofmann T., Gudermann T. Natural and synthetic modulators of SK (K(ca)2) potassium channels inhibit magnesium-dependent activity of the kinase-coupled cation channel TRPM7. Br. J. Pharmacol. 2012, 166:1357-1376.
    • (2012) Br. J. Pharmacol. , vol.166 , pp. 1357-1376
    • Chubanov, V.1    Schnitzler, M.2    Meissner, M.3    Schafer, S.4    Abstiens, K.5    Hofmann, T.6    Gudermann, T.7
  • 66
    • 79954609257 scopus 로고    scopus 로고
    • Pathophysiologically relevant levels of hydrogen peroxide induce glutamate-independent neurodegeneration that involves activation of transient receptor potential melastatin 7 channels
    • Coombes E., Jiang J., Chu X.P., Inoue K., Seeds J., Branigan D., Simon R.P., Xiong Z.G. Pathophysiologically relevant levels of hydrogen peroxide induce glutamate-independent neurodegeneration that involves activation of transient receptor potential melastatin 7 channels. Antioxid. Redox Signal. 2011, 14:1815-1827.
    • (2011) Antioxid. Redox Signal. , vol.14 , pp. 1815-1827
    • Coombes, E.1    Jiang, J.2    Chu, X.P.3    Inoue, K.4    Seeds, J.5    Branigan, D.6    Simon, R.P.7    Xiong, Z.G.8
  • 67
    • 58149389463 scopus 로고    scopus 로고
    • Restoring acid-sensing ion channel-1a in the amygdala of knock-out mice rescues fear memory but not unconditioned fear responses
    • Coryell M.W., Wunsch A.M., Haenfler J.M., Allen J.E., McBride J.L., Davidson B.L., Wemmie J.A. Restoring acid-sensing ion channel-1a in the amygdala of knock-out mice rescues fear memory but not unconditioned fear responses. J. Neurosci. 2008, 28:13738-13741.
    • (2008) J. Neurosci. , vol.28 , pp. 13738-13741
    • Coryell, M.W.1    Wunsch, A.M.2    Haenfler, J.M.3    Allen, J.E.4    McBride, J.L.5    Davidson, B.L.6    Wemmie, J.A.7
  • 70
    • 84907045404 scopus 로고    scopus 로고
    • The effect of TRPM7 suppression on the proliferation, migration and osteogenic differentiation of human dental pulp stem cells
    • (Epub ahead of print)
    • Cui L., Xu S.M., Ma D.D., Wu B.L. The effect of TRPM7 suppression on the proliferation, migration and osteogenic differentiation of human dental pulp stem cells. Int. Endod. J. 2013, (Epub ahead of print).
    • (2013) Int. Endod. J.
    • Cui, L.1    Xu, S.M.2    Ma, D.D.3    Wu, B.L.4
  • 71
  • 72
    • 0034752660 scopus 로고    scopus 로고
    • Propofol protection of sodium-hydrogen exchange activity sustains glutamate uptake during oxidative stress
    • Daskalopoulos R., Korcok J., Farhangkhgoee P., Karmazyn M., Gelb A.W., Wilson J.X. Propofol protection of sodium-hydrogen exchange activity sustains glutamate uptake during oxidative stress. Anesth. Analg. 2001, 93:1199-1204.
    • (2001) Anesth. Analg. , vol.93 , pp. 1199-1204
    • Daskalopoulos, R.1    Korcok, J.2    Farhangkhgoee, P.3    Karmazyn, M.4    Gelb, A.W.5    Wilson, J.X.6
  • 73
    • 79959379095 scopus 로고    scopus 로고
    • Repertoire of microglial and macrophage responses after spinal cord injury
    • David S., Kroner A. Repertoire of microglial and macrophage responses after spinal cord injury. Nat. Rev. Neurosci. 2011, 12:388-399.
    • (2011) Nat. Rev. Neurosci. , vol.12 , pp. 388-399
    • David, S.1    Kroner, A.2
  • 75
    • 33748462847 scopus 로고    scopus 로고
    • The sodium/hydrogen exchanger: a possible mediator of immunity
    • De Vito P. The sodium/hydrogen exchanger: a possible mediator of immunity. Cell. Immunol. 2006, 240:69-85.
    • (2006) Cell. Immunol. , vol.240 , pp. 69-85
    • De Vito, P.1
  • 76
    • 0032555350 scopus 로고    scopus 로고
    • Identification, functional expression and chromosomal localisation of a sustained human proton-gated cation channel
    • de Weille J.R., Bassilana F., Lazdunski M., Waldmann R. Identification, functional expression and chromosomal localisation of a sustained human proton-gated cation channel. FEBS Lett. 1998, 433:257-260.
    • (1998) FEBS Lett. , vol.433 , pp. 257-260
    • de Weille, J.R.1    Bassilana, F.2    Lazdunski, M.3    Waldmann, R.4
  • 78
    • 33645325125 scopus 로고    scopus 로고
    • TRPM7 channel is regulated by magnesium nucleotides via its kinase domain
    • Demeuse P., Penner R., Fleig A. TRPM7 channel is regulated by magnesium nucleotides via its kinase domain. J. Gen. Physiol. 2006, 127:421-434.
    • (2006) J. Gen. Physiol. , vol.127 , pp. 421-434
    • Demeuse, P.1    Penner, R.2    Fleig, A.3
  • 83
  • 85
    • 0035793026 scopus 로고    scopus 로고
    • Sodium-hydrogen exchangers and sodium-bicarbonate co-transporters: ontogeny of protein expression in the rat brain
    • Douglas R.M., Schmitt B.M., Xia Y., Bevensee M.O., Biemesderfer D., Boron W.F., Haddad G.G. Sodium-hydrogen exchangers and sodium-bicarbonate co-transporters: ontogeny of protein expression in the rat brain. Neuroscience 2001, 102:217-228.
    • (2001) Neuroscience , vol.102 , pp. 217-228
    • Douglas, R.M.1    Schmitt, B.M.2    Xia, Y.3    Bevensee, M.O.4    Biemesderfer, D.5    Boron, W.F.6    Haddad, G.G.7
  • 88
    • 35348849742 scopus 로고    scopus 로고
    • Upregulation of acid-sensing ion channel ASIC1a in spinal dorsal horn neurons contributes to inflammatory pain hypersensitivity
    • Duan B., Wu L.J., Yu Y.Q., Ding Y., Jing L., Xu L., Chen J., Xu T.L. Upregulation of acid-sensing ion channel ASIC1a in spinal dorsal horn neurons contributes to inflammatory pain hypersensitivity. J. Neurosci. 2007, 27:11139-11148.
    • (2007) J. Neurosci. , vol.27 , pp. 11139-11148
    • Duan, B.1    Wu, L.J.2    Yu, Y.Q.3    Ding, Y.4    Jing, L.5    Xu, L.6    Chen, J.7    Xu, T.L.8
  • 90
  • 91
    • 18544375428 scopus 로고    scopus 로고
    • Pathophysiologic role of oxidative stress-induced poly(ADP-ribose) polymerase-1 activation: focus on cell death and transcriptional regulation
    • Erdelyi K., Bakondi E., Gergely P., Szabo C., Virag L. Pathophysiologic role of oxidative stress-induced poly(ADP-ribose) polymerase-1 activation: focus on cell death and transcriptional regulation. Cell. Mol. Life Sci. 2005, 62:751-759.
    • (2005) Cell. Mol. Life Sci. , vol.62 , pp. 751-759
    • Erdelyi, K.1    Bakondi, E.2    Gergely, P.3    Szabo, C.4    Virag, L.5
  • 93
    • 33744988614 scopus 로고    scopus 로고
    • Silencing acid-sensing ion channel 1a alters cone-mediated retinal function
    • Ettaiche M., Deval E., Cougnon M., Lazdunski M., Voilley N. Silencing acid-sensing ion channel 1a alters cone-mediated retinal function. J. Neurosci. 2006, 26:5800-5809.
    • (2006) J. Neurosci. , vol.26 , pp. 5800-5809
    • Ettaiche, M.1    Deval, E.2    Cougnon, M.3    Lazdunski, M.4    Voilley, N.5
  • 94
    • 33646594976 scopus 로고    scopus 로고
    • Phospholipase A2-generated lipid mediators in the brain: the good, the bad, and the ugly
    • Farooqui A.A., Horrocks L.A. Phospholipase A2-generated lipid mediators in the brain: the good, the bad, and the ugly. Neuroscientist 2006, 12:245-260.
    • (2006) Neuroscientist , vol.12 , pp. 245-260
    • Farooqui, A.A.1    Horrocks, L.A.2
  • 98
    • 32444440545 scopus 로고    scopus 로고
    • Is zinc the link between compromises of brain perfusion (excitotoxicity) and Alzheimer's disease?
    • Frederickson C.J., Cuajungco M.P., Frederickson C.J. Is zinc the link between compromises of brain perfusion (excitotoxicity) and Alzheimer's disease?. J. Alzheimers Dis. 2005, 8:155-160.
    • (2005) J. Alzheimers Dis. , vol.8 , pp. 155-160
    • Frederickson, C.J.1    Cuajungco, M.P.2    Frederickson, C.J.3
  • 100
    • 36849009834 scopus 로고    scopus 로고
    • Acid-sensing ion channel-1 contributes to axonal degeneration in autoimmune inflammation of the central nervous system
    • Friese M.A., Craner M.J., Etzensperger R., Vergo S., Wemmie J.A., Welsh M.J., Vincent A., Fugger L. Acid-sensing ion channel-1 contributes to axonal degeneration in autoimmune inflammation of the central nervous system. Nat. Med. 2007, 13:1483-1489.
    • (2007) Nat. Med. , vol.13 , pp. 1483-1489
    • Friese, M.A.1    Craner, M.J.2    Etzensperger, R.3    Vergo, S.4    Wemmie, J.A.5    Welsh, M.J.6    Vincent, A.7    Fugger, L.8
  • 101
    • 53149103958 scopus 로고    scopus 로고
    • X-ray crystal structure of a TRPM assembly domain reveals an antiparallel four-stranded coiled-coil
    • Fujiwara Y., Minor D.L. X-ray crystal structure of a TRPM assembly domain reveals an antiparallel four-stranded coiled-coil. J. Mol. Biol. 2008, 383:854-870.
    • (2008) J. Mol. Biol. , vol.383 , pp. 854-870
    • Fujiwara, Y.1    Minor, D.L.2
  • 102
    • 82855172105 scopus 로고    scopus 로고
    • EGF enhances the migration of cancer cells by up-regulation of TRPM7
    • Gao H., Chen X., Du X., Guan B., Liu Y., Zhang H. EGF enhances the migration of cancer cells by up-regulation of TRPM7. Cell Calcium 2011, 50:559-568.
    • (2011) Cell Calcium , vol.50 , pp. 559-568
    • Gao, H.1    Chen, X.2    Du, X.3    Guan, B.4    Liu, Y.5    Zhang, H.6
  • 103
    • 27844502151 scopus 로고    scopus 로고
    • Coupling between NMDA receptor and acid-sensing ion channel contributes to ischemic neuronal death
    • Gao J., Duan B., Wang D.G., Deng X.H., Zhang G.Y., Xu L., Xu T.L. Coupling between NMDA receptor and acid-sensing ion channel contributes to ischemic neuronal death. Neuron 2005, 48:635-646.
    • (2005) Neuron , vol.48 , pp. 635-646
    • Gao, J.1    Duan, B.2    Wang, D.G.3    Deng, X.H.4    Zhang, G.Y.5    Xu, L.6    Xu, T.L.7
  • 104
    • 2342436150 scopus 로고    scopus 로고
    • Cofilin promotes actin polymerization and defines the direction of cell motility
    • Ghosh M., Song X., Mouneimne G., Sidani M., Lawrence D.S., Condeelis J.S. Cofilin promotes actin polymerization and defines the direction of cell motility. Science 2004, 304:743-746.
    • (2004) Science , vol.304 , pp. 743-746
    • Ghosh, M.1    Song, X.2    Mouneimne, G.3    Sidani, M.4    Lawrence, D.S.5    Condeelis, J.S.6
  • 105
    • 0034284153 scopus 로고    scopus 로고
    • Serine proteases and brain damage - is there a link?
    • Gingrich M.B., Traynelis S.F. Serine proteases and brain damage - is there a link?. Trends Neurosci. 2000, 23:399-407.
    • (2000) Trends Neurosci. , vol.23 , pp. 399-407
    • Gingrich, M.B.1    Traynelis, S.F.2
  • 107
    • 67949092829 scopus 로고    scopus 로고
    • Pore architecture and ion sites in acid-sensing ion channels and P2X receptors
    • Gonzales E.B., Kawate T., Gouaux E. Pore architecture and ion sites in acid-sensing ion channels and P2X receptors. Nature 2009, 460:599-604.
    • (2009) Nature , vol.460 , pp. 599-604
    • Gonzales, E.B.1    Kawate, T.2    Gouaux, E.3
  • 108
    • 0037265240 scopus 로고    scopus 로고
    • Alternative activation of macrophages
    • Gordon S. Alternative activation of macrophages. Nat. Rev. Immunol. 2003, 3:23-35.
    • (2003) Nat. Rev. Immunol. , vol.3 , pp. 23-35
    • Gordon, S.1
  • 110
    • 66049130241 scopus 로고    scopus 로고
    • Differential involvement of ASIC1a in the basolateral amygdala in fear memory and unconditioned fear responses
    • Gregoire S., Matricon J. Differential involvement of ASIC1a in the basolateral amygdala in fear memory and unconditioned fear responses. J. Neurosci. 2009, 29:6053-6054.
    • (2009) J. Neurosci. , vol.29 , pp. 6053-6054
    • Gregoire, S.1    Matricon, J.2
  • 113
    • 77954727554 scopus 로고    scopus 로고
    • Structure, function, and pharmacology of acid-sensing ion channels (ASICs): focus on ASIC1a
    • Grunder S., Chen X. Structure, function, and pharmacology of acid-sensing ion channels (ASICs): focus on ASIC1a. Int. J. Physiol. Pathophysiol. Pharmacol. 2010, 2:73-94.
    • (2010) Int. J. Physiol. Pathophysiol. Pharmacol. , vol.2 , pp. 73-94
    • Grunder, S.1    Chen, X.2
  • 114
  • 116
    • 84886779142 scopus 로고    scopus 로고
    • Transient receptor potential melastatin 7 is involved in oestrogen receptor-negative metastatic breast cancer cells migration through its kinase domain
    • Guilbert A., Gautier M., Dhennin-Duthille I., Rybarczyk P., Sahni J., Sevestre H., Scharenberg A.M., Ouadid-Ahidouch H. Transient receptor potential melastatin 7 is involved in oestrogen receptor-negative metastatic breast cancer cells migration through its kinase domain. Eur. J. Cancer 2013, 49:3694-3707.
    • (2013) Eur. J. Cancer , vol.49 , pp. 3694-3707
    • Guilbert, A.1    Gautier, M.2    Dhennin-Duthille, I.3    Rybarczyk, P.4    Sahni, J.5    Sevestre, H.6    Scharenberg, A.M.7    Ouadid-Ahidouch, H.8
  • 117
    • 33644854944 scopus 로고    scopus 로고
    • Going with the flow: smooth muscle TRPM7 channels and the vascular response to blood flow
    • Gurney A.M. Going with the flow: smooth muscle TRPM7 channels and the vascular response to blood flow. Circ. Res. 2006, 98:163-164.
    • (2006) Circ. Res. , vol.98 , pp. 163-164
    • Gurney, A.M.1
  • 118
    • 1542315556 scopus 로고    scopus 로고
    • Association of outcome with early stroke treatment: pooled analysis of ATLANTIS, ECASS, and NINDS rt-PA stroke trials
    • Hacke W., et al. Association of outcome with early stroke treatment: pooled analysis of ATLANTIS, ECASS, and NINDS rt-PA stroke trials. Lancet 2004, 363:768-774.
    • (2004) Lancet , vol.363 , pp. 768-774
    • Hacke, W.1
  • 120
    • 1942502810 scopus 로고    scopus 로고
    • Regulation of tight junctions and loss of barrier function in pathophysiology
    • Harhaj N.S., Antonetti D.A. Regulation of tight junctions and loss of barrier function in pathophysiology. Int. J. Biochem. Cell Biol. 2004, 36:1206-1237.
    • (2004) Int. J. Biochem. Cell Biol. , vol.36 , pp. 1206-1237
    • Harhaj, N.S.1    Antonetti, D.A.2
  • 121
    • 21344437332 scopus 로고    scopus 로고
    • Function and pharmacology of TRPM cation channels
    • Harteneck C. Function and pharmacology of TRPM cation channels. Naunyn. Schmiedebergs Arch. Pharmacol. 2005, 371:307-314.
    • (2005) Naunyn. Schmiedebergs Arch. Pharmacol. , vol.371 , pp. 307-314
    • Harteneck, C.1
  • 122
    • 0032786125 scopus 로고    scopus 로고
    • Dynorphin A (1-13) neurotoxicity in vitro: opioid and non-opioid mechanisms in mouse spinal cord neurons
    • Hauser K.F., Foldes J.K., Turbek C.S. Dynorphin A (1-13) neurotoxicity in vitro: opioid and non-opioid mechanisms in mouse spinal cord neurons. Exp. Neurol. 1999, 160:361-375.
    • (1999) Exp. Neurol. , vol.160 , pp. 361-375
    • Hauser, K.F.1    Foldes, J.K.2    Turbek, C.S.3
  • 125
    • 0022531495 scopus 로고
    • Calcium channel selectivity for divalent and monovalent cations. Voltage and concentration dependence of single channel current in ventricular heart cells
    • Hess P., Lansman J.B., Tsien R.W. Calcium channel selectivity for divalent and monovalent cations. Voltage and concentration dependence of single channel current in ventricular heart cells. J. Gen. Physiol. 1986, 88:293-319.
    • (1986) J. Gen. Physiol. , vol.88 , pp. 293-319
    • Hess, P.1    Lansman, J.B.2    Tsien, R.W.3
  • 126
    • 84867641191 scopus 로고    scopus 로고
    • Safety and efficacy of NA-1 in patients with iatrogenic stroke after endovascular aneurysm repair (ENACT): a phase 2, randomised, double-blind, placebo-controlled trial
    • Hill M.D., et al. Safety and efficacy of NA-1 in patients with iatrogenic stroke after endovascular aneurysm repair (ENACT): a phase 2, randomised, double-blind, placebo-controlled trial. Lancet Neurol. 2012, 11:942-950.
    • (2012) Lancet Neurol. , vol.11 , pp. 942-950
    • Hill, M.D.1
  • 127
    • 78650633367 scopus 로고    scopus 로고
    • Identification of a calcium permeable human acid-sensing ion channel 1 transcript variant
    • Hoagland E.N., Sherwood T.W., Lee K.G., Walker C.J., Askwith C.C. Identification of a calcium permeable human acid-sensing ion channel 1 transcript variant. J. Biol. Chem. 2010, 285:41852-41862.
    • (2010) J. Biol. Chem. , vol.285 , pp. 41852-41862
    • Hoagland, E.N.1    Sherwood, T.W.2    Lee, K.G.3    Walker, C.J.4    Askwith, C.C.5
  • 129
    • 0035869474 scopus 로고    scopus 로고
    • Extracellular ATP or ADP induce chemotaxis of cultured microglia through Gi/o-coupled P2Y receptors
    • Honda S., Sasaki Y., Ohsawa K., Imai Y., Nakamura Y., Inoue K., Kohsaka S. Extracellular ATP or ADP induce chemotaxis of cultured microglia through Gi/o-coupled P2Y receptors. J. Neurosci. 2001, 21(6):1975-1982.
    • (2001) J. Neurosci. , vol.21 , Issue.6 , pp. 1975-1982
    • Honda, S.1    Sasaki, Y.2    Ohsawa, K.3    Imai, Y.4    Nakamura, Y.5    Inoue, K.6    Kohsaka, S.7
  • 130
    • 84868209611 scopus 로고    scopus 로고
    • Microglia/macrophage polarization dynamics reveal novel mechanism of injury expansion after focal cerebral ischemia
    • Hu X., Li P., Guo Y., Wang H., Leak R.K., Chen S., Gao Y., Chen J. Microglia/macrophage polarization dynamics reveal novel mechanism of injury expansion after focal cerebral ischemia. Stroke 2012, 43:3063-3070.
    • (2012) Stroke , vol.43 , pp. 3063-3070
    • Hu, X.1    Li, P.2    Guo, Y.3    Wang, H.4    Leak, R.K.5    Chen, S.6    Gao, Y.7    Chen, J.8
  • 135
    • 77951239305 scopus 로고    scopus 로고
    • Zinc-induced neurotoxicity mediated by transient receptor potential melastatin 7 channels
    • Inoue K., Branigan D., Xiong Z.G. Zinc-induced neurotoxicity mediated by transient receptor potential melastatin 7 channels. J. Biol. Chem. 2010, 285:7430-7439.
    • (2010) J. Biol. Chem. , vol.285 , pp. 7430-7439
    • Inoue, K.1    Branigan, D.2    Xiong, Z.G.3
  • 136
    • 67651085449 scopus 로고    scopus 로고
    • Silencing TRPM7 promotes growth/proliferation and nitric oxide production of vascular endothelial cells via the ERK pathway
    • Inoue K., Xiong Z.G. Silencing TRPM7 promotes growth/proliferation and nitric oxide production of vascular endothelial cells via the ERK pathway. Cardiovasc. Res. 2009, 83:547-557.
    • (2009) Cardiovasc. Res. , vol.83 , pp. 547-557
    • Inoue, K.1    Xiong, Z.G.2
  • 137
    • 34548813656 scopus 로고    scopus 로고
    • Structure of acid-sensing ion channel 1 at 1.9Å resolution and low pH
    • Jasti J., Furukawa H., Gonzales E.B., Gouaux E. Structure of acid-sensing ion channel 1 at 1.9Å resolution and low pH. Nature 2007, 449:316-323.
    • (2007) Nature , vol.449 , pp. 316-323
    • Jasti, J.1    Furukawa, H.2    Gonzales, E.B.3    Gouaux, E.4
  • 139
    • 76949106362 scopus 로고    scopus 로고
    • Evaluation of the role of nitric oxide in acid sensing ion channel mediated cell death
    • Jetti S.K., Swain S.M., Majumder S., Chatterjee S., Poornima V., Bera A.K. Evaluation of the role of nitric oxide in acid sensing ion channel mediated cell death. Nitric Oxide 2010, 22:213-219.
    • (2010) Nitric Oxide , vol.22 , pp. 213-219
    • Jetti, S.K.1    Swain, S.M.2    Majumder, S.3    Chatterjee, S.4    Poornima, V.5    Bera, A.K.6
  • 140
    • 41449089413 scopus 로고    scopus 로고
    • TrkA pathway(s) is involved in regulation of TRPM7 expression in hippocampal neurons subjected to ischemic-reperfusion and oxygen-glucose deprivation
    • Jiang H., Tian S.L., Zeng Y., Li L.L., Shi J. TrkA pathway(s) is involved in regulation of TRPM7 expression in hippocampal neurons subjected to ischemic-reperfusion and oxygen-glucose deprivation. Brain Res. Bull. 2008, 76:124-130.
    • (2008) Brain Res. Bull. , vol.76 , pp. 124-130
    • Jiang, H.1    Tian, S.L.2    Zeng, Y.3    Li, L.L.4    Shi, J.5
  • 141
    • 23744484892 scopus 로고    scopus 로고
    • Potentiation of TRPM7 inward currents by protons
    • Jiang J., Li M., Yue L. Potentiation of TRPM7 inward currents by protons. J. Gen. Physiol. 2005, 126:137-150.
    • (2005) J. Gen. Physiol. , vol.126 , pp. 137-150
    • Jiang, J.1    Li, M.2    Yue, L.3
  • 142
    • 36348964907 scopus 로고    scopus 로고
    • Transient receptor potential melastatin 7-like current in human head and neck carcinoma cells: role in cell proliferation
    • Jiang J., Li M.H., Inoue K., Chu X.P., Seeds J., Xiong Z.G. Transient receptor potential melastatin 7-like current in human head and neck carcinoma cells: role in cell proliferation. Cancer Res. 2007, 67:10929-10938.
    • (2007) Cancer Res. , vol.67 , pp. 10929-10938
    • Jiang, J.1    Li, M.H.2    Inoue, K.3    Chu, X.P.4    Seeds, J.5    Xiong, Z.G.6
  • 145
    • 77952513645 scopus 로고    scopus 로고
    • Inflammatory mechanisms in ischemic stroke: role of inflammatory cells
    • Jin R., Yang G., Li G. Inflammatory mechanisms in ischemic stroke: role of inflammatory cells. J. Leukoc. Biol. 2010, 87(5):779-789.
    • (2010) J. Leukoc. Biol. , vol.87 , Issue.5 , pp. 779-789
    • Jin, R.1    Yang, G.2    Li, G.3
  • 146
    • 69949158818 scopus 로고    scopus 로고
    • Knockdown of ASIC1 and epithelial sodium channel subunits inhibits glioblastoma whole cell current and cell migration
    • Kapoor N., Bartoszewski R., Qadri Y.J., Bebok Z., Bubien J.K., Fuller C.M., Benos D.J. Knockdown of ASIC1 and epithelial sodium channel subunits inhibits glioblastoma whole cell current and cell migration. J. Biol. Chem. 2009, 284:24526-24541.
    • (2009) J. Biol. Chem. , vol.284 , pp. 24526-24541
    • Kapoor, N.1    Bartoszewski, R.2    Qadri, Y.J.3    Bebok, Z.4    Bubien, J.K.5    Fuller, C.M.6    Benos, D.J.7
  • 148
    • 84880332023 scopus 로고    scopus 로고
    • NHE-1: still a viable therapeutic target
    • Karmazyn M. NHE-1: still a viable therapeutic target. J. Mol. Cell. Cardiol. 2013, 61:77-82.
    • (2013) J. Mol. Cell. Cardiol. , vol.61 , pp. 77-82
    • Karmazyn, M.1
  • 149
    • 0032749318 scopus 로고    scopus 로고
    • The myocardial Na(+)-H(+) exchange: structure, regulation, and its role in heart disease
    • Karmazyn M., Gan X.T., Humphreys R.A., Yoshida H., Kusumoto K. The myocardial Na(+)-H(+) exchange: structure, regulation, and its role in heart disease. Circ. Res. 1999, 85:777-786.
    • (1999) Circ. Res. , vol.85 , pp. 777-786
    • Karmazyn, M.1    Gan, X.T.2    Humphreys, R.A.3    Yoshida, H.4    Kusumoto, K.5
  • 150
    • 84867654740 scopus 로고    scopus 로고
    • Is the door open again for neuroprotection trials in stroke?
    • Kaste M. Is the door open again for neuroprotection trials in stroke?. Lancet Neurol. 2012, 11:930-931.
    • (2012) Lancet Neurol. , vol.11 , pp. 930-931
    • Kaste, M.1
  • 151
    • 33646679415 scopus 로고    scopus 로고
    • N-methyl-isobutyl-amiloride ameliorates brain injury when commenced before hypoxia ischemia in neonatal mice
    • Kendall G.S., Robertson N.J., Iwata O., Peebles D., Raivich G. N-methyl-isobutyl-amiloride ameliorates brain injury when commenced before hypoxia ischemia in neonatal mice. Pediatr. Res. 2006, 59:227-231.
    • (2006) Pediatr. Res. , vol.59 , pp. 227-231
    • Kendall, G.S.1    Robertson, N.J.2    Iwata, O.3    Peebles, D.4    Raivich, G.5
  • 152
    • 0037380767 scopus 로고    scopus 로고
    • Polyvalent cations as permeant probes of MIC and TRPM7 pores
    • Kerschbaum H.H., Kozak J.A., Cahalan M.D. Polyvalent cations as permeant probes of MIC and TRPM7 pores. Biophys. J. 2003, 84:2293-2305.
    • (2003) Biophys. J. , vol.84 , pp. 2293-2305
    • Kerschbaum, H.H.1    Kozak, J.A.2    Cahalan, M.D.3
  • 153
    • 0034780077 scopus 로고    scopus 로고
    • Trophic factor withdrawal: p38 mitogen-activated protein kinase activates NHE1, which induces intracellular alkalinization
    • Khaled A.R., Moor A.N., Li A., Kim K., Ferris D.K., Muegge K., Fisher R.J., Fliegel L., Durum S.K. Trophic factor withdrawal: p38 mitogen-activated protein kinase activates NHE1, which induces intracellular alkalinization. Mol. Cell. Biol. 2001, 21:7545-7557.
    • (2001) Mol. Cell. Biol. , vol.21 , pp. 7545-7557
    • Khaled, A.R.1    Moor, A.N.2    Li, A.3    Kim, K.4    Ferris, D.K.5    Muegge, K.6    Fisher, R.J.7    Fliegel, L.8    Durum, S.K.9
  • 154
    • 84876032265 scopus 로고    scopus 로고
    • Involvement of melastatin type transient receptor potential 7 channels in ginsenoside Rd-induced apoptosis in gastric and breast cancer cells
    • Kim B.J. Involvement of melastatin type transient receptor potential 7 channels in ginsenoside Rd-induced apoptosis in gastric and breast cancer cells. J. Ginseng Res. 2013, 37:201-209.
    • (2013) J. Ginseng Res. , vol.37 , pp. 201-209
    • Kim, B.J.1
  • 155
    • 0028138639 scopus 로고
    • Blockade of ornithine decarboxylase enzyme protects against ischemic brain damage
    • Kindy M.S., Hu Y., Dempsey R.J. Blockade of ornithine decarboxylase enzyme protects against ischemic brain damage. J. Cereb. Blood Flow Metab. 1994, 14:1040-1045.
    • (1994) J. Cereb. Blood Flow Metab. , vol.14 , pp. 1040-1045
    • Kindy, M.S.1    Hu, Y.2    Dempsey, R.J.3
  • 157
    • 0028843311 scopus 로고
    • G alpha q and G alpha 13 regulate NHE-1 and intracellular calcium in epithelial cells
    • Kitamura K., Singer W.D., Cano A., Miller R.T. G alpha q and G alpha 13 regulate NHE-1 and intracellular calcium in epithelial cells. Am. J. Physiol. 1995, 268:C101-C110.
    • (1995) Am. J. Physiol. , vol.268 , pp. C101-C110
    • Kitamura, K.1    Singer, W.D.2    Cano, A.3    Miller, R.T.4
  • 158
    • 0029777299 scopus 로고    scopus 로고
    • The role of zinc in selective neuronal death after transient global cerebral ischemia
    • Koh J.Y., Suh S.W., Gwag B.J., He Y.Y., Hsu C.Y., Choi D.W. The role of zinc in selective neuronal death after transient global cerebral ischemia. Science 1996, 272:1013-1016.
    • (1996) Science , vol.272 , pp. 1013-1016
    • Koh, J.Y.1    Suh, S.W.2    Gwag, B.J.3    He, Y.Y.4    Hsu, C.Y.5    Choi, D.W.6
  • 159
    • 0037307260 scopus 로고    scopus 로고
    • MIC channels are inhibited by internal divalent cations but not ATP
    • Kozak J.A., Cahalan M.D. MIC channels are inhibited by internal divalent cations but not ATP. Biophys. J. 2003, 84:922-927.
    • (2003) Biophys. J. , vol.84 , pp. 922-927
    • Kozak, J.A.1    Cahalan, M.D.2
  • 160
    • 33750515856 scopus 로고    scopus 로고
    • The TRPM7 ion channel functions in cholinergic synaptic vesicles and affects transmitter release
    • Krapivinsky G., Mochida S., Krapivinsky L., Cibulsky S.M., Clapham D.E. The TRPM7 ion channel functions in cholinergic synaptic vesicles and affects transmitter release. Neuron 2006, 52:485-496.
    • (2006) Neuron , vol.52 , pp. 485-496
    • Krapivinsky, G.1    Mochida, S.2    Krapivinsky, L.3    Cibulsky, S.M.4    Clapham, D.E.5
  • 161
    • 0030222037 scopus 로고    scopus 로고
    • Microglia: a sensor for pathological events in the CNS
    • Kreutzberg G.W. Microglia: a sensor for pathological events in the CNS. Trends Neurosci. 1996, 19:312-318.
    • (1996) Trends Neurosci. , vol.19 , pp. 312-318
    • Kreutzberg, G.W.1
  • 162
    • 0042926849 scopus 로고    scopus 로고
    • The ASICs: signaling molecules? Modulators?
    • Krishtal O. The ASICs: signaling molecules? Modulators?. Trends Neurosci. 2003, 26:477-483.
    • (2003) Trends Neurosci. , vol.26 , pp. 477-483
    • Krishtal, O.1
  • 163
    • 84865416318 scopus 로고    scopus 로고
    • KCa3.1 and TRPM7 channels at the uropod regulate migration of activated human T cells
    • Kuras Z., Yun Y.H., Chimote A.A., Neumeier L., Conforti L. KCa3.1 and TRPM7 channels at the uropod regulate migration of activated human T cells. PLoS ONE 2012, 7:e43859.
    • (2012) PLoS ONE , vol.7
    • Kuras, Z.1    Yun, Y.H.2    Chimote, A.A.3    Neumeier, L.4    Conforti, L.5
  • 164
    • 79955645278 scopus 로고    scopus 로고
    • Stroke intervention pathways: NMDA receptors and beyond
    • Lai T.W., Shyu W.C., Wang Y.T. Stroke intervention pathways: NMDA receptors and beyond. Trends Mol. Med. 2011, 17:266-275.
    • (2011) Trends Mol. Med. , vol.17 , pp. 266-275
    • Lai, T.W.1    Shyu, W.C.2    Wang, Y.T.3
  • 165
    • 33847785649 scopus 로고    scopus 로고
    • Selective ablation of proliferating microglial cells exacerbates ischemic injury in the brain
    • Lalancette-Hebert M., Gowing G., Simard A., Weng Y.C., Kriz J. Selective ablation of proliferating microglial cells exacerbates ischemic injury in the brain. J. Neurosci. 2007, 27(10):2596-2605.
    • (2007) J. Neurosci. , vol.27 , Issue.10 , pp. 2596-2605
    • Lalancette-Hebert, M.1    Gowing, G.2    Simard, A.3    Weng, Y.C.4    Kriz, J.5
  • 167
    • 68849124098 scopus 로고    scopus 로고
    • Cerebral microvascular endothelial cell Na/H exchange: evidence for the presence of NHE1 and NHE2 isoforms and regulation by arginine vasopressin
    • Lam T.I., Wise P.M., O'Donnell M.E. Cerebral microvascular endothelial cell Na/H exchange: evidence for the presence of NHE1 and NHE2 isoforms and regulation by arginine vasopressin. Am. J. Physiol. Cell Physiol. 2009, 297:C278-C289.
    • (2009) Am. J. Physiol. Cell Physiol. , vol.297 , pp. C278-C289
    • Lam, T.I.1    Wise, P.M.2    O'Donnell, M.E.3
  • 172
    • 84878686651 scopus 로고    scopus 로고
    • Subunit and frequency-dependent inhibition of acid sensing ion channels by local anesthetic tetracaine
    • Leng T., Lin J., Cottrell J.E., Xiong Z.G. Subunit and frequency-dependent inhibition of acid sensing ion channels by local anesthetic tetracaine. Mol. Pain 2013, 9:27.
    • (2013) Mol. Pain , vol.9 , pp. 27
    • Leng, T.1    Lin, J.2    Cottrell, J.E.3    Xiong, Z.G.4
  • 173
    • 33646140352 scopus 로고    scopus 로고
    • Functional characterization of homo- and heteromeric channel kinases TRPM6 and TRPM7
    • Li M., Jiang J., Yue L. Functional characterization of homo- and heteromeric channel kinases TRPM6 and TRPM7. J. Gen. Physiol. 2006, 127:525-537.
    • (2006) J. Gen. Physiol. , vol.127 , pp. 525-537
    • Li, M.1    Jiang, J.2    Yue, L.3
  • 175
    • 84884281198 scopus 로고    scopus 로고
    • Acid-sensing ion channel 1a is involved in acid-induced osteoclastogenesis by regulating activation of the transcription factor NFATc1
    • Li X., Xu R.S., Jiang D.L., He X.L., Jin C., Lu W.G., Su Q., Yuan F.L. Acid-sensing ion channel 1a is involved in acid-induced osteoclastogenesis by regulating activation of the transcription factor NFATc1. FEBS Lett. 2013, 587:3236-3242.
    • (2013) FEBS Lett. , vol.587 , pp. 3236-3242
    • Li, X.1    Xu, R.S.2    Jiang, D.L.3    He, X.L.4    Jin, C.5    Lu, W.G.6    Su, Q.7    Yuan, F.L.8
  • 176
    • 84891794463 scopus 로고    scopus 로고
    • The interaction of transient receptor potential melastatin 7 with macrophages promotes vascular adventitial remodeling in transverse aortic constriction rats
    • Li Y., Jiang H., Ruan C., Zhong J., Gao P., Zhu D., Niu W., Guo S. The interaction of transient receptor potential melastatin 7 with macrophages promotes vascular adventitial remodeling in transverse aortic constriction rats. Hypertens. Res. 2013, 37:35-42.
    • (2013) Hypertens. Res. , vol.37 , pp. 35-42
    • Li, Y.1    Jiang, H.2    Ruan, C.3    Zhong, J.4    Gao, P.5    Zhu, D.6    Niu, W.7    Guo, S.8
  • 179
    • 79953183584 scopus 로고    scopus 로고
    • Inhibition of acid sensing ion channel currents by lidocaine in cultured mouse cortical neurons
    • Lin J., Chu X., Maysami S., Li M., Si H., Cottrell J.E., Simon R.P., Xiong Z. Inhibition of acid sensing ion channel currents by lidocaine in cultured mouse cortical neurons. Anesth. Analg. 2011, 112:977-981.
    • (2011) Anesth. Analg. , vol.112 , pp. 977-981
    • Lin, J.1    Chu, X.2    Maysami, S.3    Li, M.4    Si, H.5    Cottrell, J.E.6    Simon, R.P.7    Xiong, Z.8
  • 180
    • 16644371488 scopus 로고    scopus 로고
    • Microdialysis analyzer and flame atomic absorption spectrometry in the determination of blood glucose, lactate and magnesium in gerbils subjected to cerebral ischemia/reperfusion
    • Lin M.C., Huang Y.L., Liu H.W., Yang D.Y., Lee J.B., Cheng F.C. Microdialysis analyzer and flame atomic absorption spectrometry in the determination of blood glucose, lactate and magnesium in gerbils subjected to cerebral ischemia/reperfusion. J. Am. Coll. Nutr. 2004, 23:556S-560S.
    • (2004) J. Am. Coll. Nutr. , vol.23 , pp. 556S-560S
    • Lin, M.C.1    Huang, Y.L.2    Liu, H.W.3    Yang, D.Y.4    Lee, J.B.5    Cheng, F.C.6
  • 182
    • 33644940150 scopus 로고    scopus 로고
    • Involvement of TRP-like channels in the acute ischemic response of hippocampal CA1 neurons in brain slices
    • Lipski J., Park T.I., Li D., Lee S.C., Trevarton A.J., Chung K.K., Freestone P.S., Bai J.Z. Involvement of TRP-like channels in the acute ischemic response of hippocampal CA1 neurons in brain slices. Brain Res. 2006, 1077:187-199.
    • (2006) Brain Res. , vol.1077 , pp. 187-199
    • Lipski, J.1    Park, T.I.2    Li, D.3    Lee, S.C.4    Trevarton, A.J.5    Chung, K.K.6    Freestone, P.S.7    Bai, J.Z.8
  • 183
    • 0032845121 scopus 로고    scopus 로고
    • Ischemic cell death in brain neurons
    • Lipton P. Ischemic cell death in brain neurons. Physiol. Rev. 1999, 79:1431-1568.
    • (1999) Physiol. Rev. , vol.79 , pp. 1431-1568
    • Lipton, P.1
  • 184
    • 0028762647 scopus 로고
    • Excitatory amino acids as a final common pathway for neurologic disorders
    • Lipton S.A., Rosenberg P.A. Excitatory amino acids as a final common pathway for neurologic disorders. N. Engl. J. Med. 1994, 330:613-622.
    • (1994) N. Engl. J. Med. , vol.330 , pp. 613-622
    • Lipton, S.A.1    Rosenberg, P.A.2
  • 189
    • 34948831682 scopus 로고    scopus 로고
    • ERK1/2-p90RSK-mediated phosphorylation of Na(+)/H(+) exchanger isoform: 1. A role in ischemic neuronal death
    • Luo J., Kintner D.B., Shull G.E., Sun D. ERK1/2-p90RSK-mediated phosphorylation of Na(+)/H(+) exchanger isoform: 1. A role in ischemic neuronal death. J. Biol. Chem. 2007, 282:28274-28284.
    • (2007) J. Biol. Chem. , vol.282 , pp. 28274-28284
    • Luo, J.1    Kintner, D.B.2    Shull, G.E.3    Sun, D.4
  • 190
    • 34547778503 scopus 로고    scopus 로고
    • Physiology and pathophysiology of Na(+)/H(+) exchange isoform 1 in the central nervous system
    • Luo J., Sun D. Physiology and pathophysiology of Na(+)/H(+) exchange isoform 1 in the central nervous system. Curr. Neurovasc. Res. 2007, 4:205-215.
    • (2007) Curr. Neurovasc. Res. , vol.4 , pp. 205-215
    • Luo, J.1    Sun, D.2
  • 194
    • 0038121757 scopus 로고    scopus 로고
    • An overview of inhibitors of Na(+)/H(+) exchanger
    • Masereel B., Pochet L., Laeckmann D. An overview of inhibitors of Na(+)/H(+) exchanger. Eur. J. Med. Chem. 2003, 38:547-554.
    • (2003) Eur. J. Med. Chem. , vol.38 , pp. 547-554
    • Masereel, B.1    Pochet, L.2    Laeckmann, D.3
  • 197
  • 198
    • 62249172184 scopus 로고    scopus 로고
    • Distribution of acid-sensing ion channel 3 in the rat hypothalamus
    • Meng Q.Y., Wang W., Chen X.N., Xu T.L., Zhou J.N. Distribution of acid-sensing ion channel 3 in the rat hypothalamus. Neuroscience 2009, 159:1126-1134.
    • (2009) Neuroscience , vol.159 , pp. 1126-1134
    • Meng, Q.Y.1    Wang, W.2    Chen, X.N.3    Xu, T.L.4    Zhou, J.N.5
  • 200
    • 85068306222 scopus 로고    scopus 로고
    • Suppression of renal TRPM7 may alleviate kidney injury in the renal transplantation
    • (Epub ahead of print [PMID: 24258314])
    • Meng Z., Cao R., Wang Y., Cao H., Liu T., Yang Z., Wang X. Suppression of renal TRPM7 may alleviate kidney injury in the renal transplantation. World J. Urol. 2013, (Epub ahead of print [PMID: 24258314]).
    • (2013) World J. Urol.
    • Meng, Z.1    Cao, R.2    Wang, Y.3    Cao, H.4    Liu, T.5    Yang, Z.6    Wang, X.7
  • 201
    • 84861863110 scopus 로고    scopus 로고
    • Expression of transient receptor potential melastatin 7 up-regulated in the early stage of renal ischemia-reperfusion
    • Meng Z., Wang X., Yang Z., Xiang F. Expression of transient receptor potential melastatin 7 up-regulated in the early stage of renal ischemia-reperfusion. Transplant. Proc. 2012, 44:1206-1210.
    • (2012) Transplant. Proc. , vol.44 , pp. 1206-1210
    • Meng, Z.1    Wang, X.2    Yang, Z.3    Xiang, F.4
  • 205
    • 0035844256 scopus 로고    scopus 로고
    • + exchanger-directed protein kinases in the ischemic and ischemic-reperfused rat myocardium
    • + exchanger-directed protein kinases in the ischemic and ischemic-reperfused rat myocardium. J. Biol. Chem. 2001, 276:16113-16122.
    • (2001) J. Biol. Chem. , vol.276 , pp. 16113-16122
    • Moor, A.N.1    Gan, X.T.2    Karmazyn, M.3    Fliegel, L.4
  • 206
    • 56749174940 scopus 로고    scopus 로고
    • Exploring the full spectrum of macrophage activation
    • Mosser D.M., Edwards J.P. Exploring the full spectrum of macrophage activation. Nat. Rev. Immunol. 2008, 8:958-969.
    • (2008) Nat. Rev. Immunol. , vol.8 , pp. 958-969
    • Mosser, D.M.1    Edwards, J.P.2
  • 207
    • 31344432053 scopus 로고    scopus 로고
    • Phospholipase A2, reactive oxygen species, and lipid peroxidation in cerebral ischemia
    • Muralikrishna A.R., Hatcher J.F. Phospholipase A2, reactive oxygen species, and lipid peroxidation in cerebral ischemia. Free Radic. Biol. Med. 2006, 40:376-387.
    • (2006) Free Radic. Biol. Med. , vol.40 , pp. 376-387
    • Muralikrishna, A.R.1    Hatcher, J.F.2
  • 209
    • 12544258841 scopus 로고    scopus 로고
    • + exchanger isoforms are distributed to Golgi and post-Golgi compartments and are involved in organelle pH regulation
    • + exchanger isoforms are distributed to Golgi and post-Golgi compartments and are involved in organelle pH regulation. J. Biol. Chem. 2005, 280:1561-1572.
    • (2005) J. Biol. Chem. , vol.280 , pp. 1561-1572
    • Nakamura, N.1    Tanaka, S.2    Teko, Y.3    Mitsui, K.4    Kanazawa, H.5
  • 211
    • 0025817497 scopus 로고
    • Dynamics of interstitial and intracellular pH in evolving brain infarct
    • Nedergaard M., Kraig R.P., Tanabe J., Pulsinelli W.A. Dynamics of interstitial and intracellular pH in evolving brain infarct. Am. J. Physiol. 1991, 260:R581-R588.
    • (1991) Am. J. Physiol. , vol.260 , pp. R581-R588
    • Nedergaard, M.1    Kraig, R.P.2    Tanabe, J.3    Pulsinelli, W.A.4
  • 212
    • 0034951136 scopus 로고    scopus 로고
    • DNA minor-groove recognition by small molecules
    • Neidle S. DNA minor-groove recognition by small molecules. Nat. Prod. Rep. 2001, 18:291-309.
    • (2001) Nat. Prod. Rep. , vol.18 , pp. 291-309
    • Neidle, S.1
  • 213
    • 1642539064 scopus 로고    scopus 로고
    • New and future endovascular treatment strategies for acute ischemic stroke
    • Nesbit G.M., Luh G., Tien R., Barnwell S.L. New and future endovascular treatment strategies for acute ischemic stroke. J. Vasc. Interv. Radiol. 2004, 15:S103-S110.
    • (2004) J. Vasc. Interv. Radiol. , vol.15 , pp. S103-S110
    • Nesbit, G.M.1    Luh, G.2    Tien, R.3    Barnwell, S.L.4
  • 214
    • 0025052336 scopus 로고
    • The release and uptake of excitatory amino acids
    • Nicholls D., Attwell D. The release and uptake of excitatory amino acids. Trends Pharmacol. Sci. 1990, 11:462-468.
    • (1990) Trends Pharmacol. Sci. , vol.11 , pp. 462-468
    • Nicholls, D.1    Attwell, D.2
  • 215
    • 79952683619 scopus 로고    scopus 로고
    • The transient receptor potential family of ion channels
    • Nilius B., Owsianik G. The transient receptor potential family of ion channels. Genome Biol. 2011, 12:218-312.
    • (2011) Genome Biol. , vol.12 , pp. 218-312
    • Nilius, B.1    Owsianik, G.2
  • 216
    • 0030802319 scopus 로고    scopus 로고
    • Epidermal growth factor is a motility factor for microglial cells in vitro: evidence for EGF receptor expression
    • Nolte C., Kirchhoff F., Kettenmann H. Epidermal growth factor is a motility factor for microglial cells in vitro: evidence for EGF receptor expression. Eur. J. Neurosci. 1997, 9:1690-1698.
    • (1997) Eur. J. Neurosci. , vol.9 , pp. 1690-1698
    • Nolte, C.1    Kirchhoff, F.2    Kettenmann, H.3
  • 217
    • 0035907355 scopus 로고    scopus 로고
    • + exchanger localized to the trans-Golgi network
    • + exchanger localized to the trans-Golgi network. J. Biol. Chem. 2001, 276:17387-17394.
    • (2001) J. Biol. Chem. , vol.276 , pp. 17387-17394
    • Numata, M.1    Orlowski, J.2
  • 218
  • 219
    • 33846312821 scopus 로고    scopus 로고
    • TRPM7 is a stretch- and swelling-activated cation channel involved in volume regulation in human epithelial cells
    • Numata T., Shimizu T., Okada Y. TRPM7 is a stretch- and swelling-activated cation channel involved in volume regulation in human epithelial cells. Am. J. Physiol. Cell Physiol. 2007, 292:C460-C467.
    • (2007) Am. J. Physiol. Cell Physiol. , vol.292 , pp. C460-C467
    • Numata, T.1    Shimizu, T.2    Okada, Y.3
  • 221
    • 84873409066 scopus 로고    scopus 로고
    • Intravenous HOE-642 reduces brain edema and Na uptake in the rat permanent middle cerebral artery occlusion model of stroke: evidence for participation of the blood-brain barrier Na/H exchanger
    • O'Donnell M.E., Chen Y.J., Lam T.I., Taylor K.C., Walton J.H., Anderson S.E. Intravenous HOE-642 reduces brain edema and Na uptake in the rat permanent middle cerebral artery occlusion model of stroke: evidence for participation of the blood-brain barrier Na/H exchanger. J. Cereb. Blood Flow Metab. 2013, 33:225-234.
    • (2013) J. Cereb. Blood Flow Metab. , vol.33 , pp. 225-234
    • O'Donnell, M.E.1    Chen, Y.J.2    Lam, T.I.3    Taylor, K.C.4    Walton, J.H.5    Anderson, S.E.6
  • 222
    • 33644855566 scopus 로고    scopus 로고
    • Functional TRPM7 channels accumulate at the plasma membrane in response to fluid flow
    • Oancea E., Wolfe J.T., Clapham D.E. Functional TRPM7 channels accumulate at the plasma membrane in response to fluid flow. Circ. Res. 2006, 98:245-253.
    • (2006) Circ. Res. , vol.98 , pp. 245-253
    • Oancea, E.1    Wolfe, J.T.2    Clapham, D.E.3
  • 224
    • 1242272754 scopus 로고    scopus 로고
    • Diversity of the mammalian sodium/proton exchanger SLC9 gene family
    • Orlowski J., Grinstein S. Diversity of the mammalian sodium/proton exchanger SLC9 gene family. Pflugers Arch. 2004, 447:549-565.
    • (2004) Pflugers Arch. , vol.447 , pp. 549-565
    • Orlowski, J.1    Grinstein, S.2
  • 228
    • 79952986535 scopus 로고    scopus 로고
    • The role of ASIC1a in neuroprotection elicited by quercetin in focal cerebral ischemia
    • Pandey A.K., Hazari P.P., Patnaik R., Mishra A.K. The role of ASIC1a in neuroprotection elicited by quercetin in focal cerebral ischemia. Brain Res. 2011, 1383:289-299.
    • (2011) Brain Res. , vol.1383 , pp. 289-299
    • Pandey, A.K.1    Hazari, P.P.2    Patnaik, R.3    Mishra, A.K.4
  • 229
    • 79251634933 scopus 로고    scopus 로고
    • The effect of Na(+)/H(+) exchanger-1 inhibition by sabiporide on blood-brain barrier dysfunction after ischemia/hypoxia in vivo and in vitro
    • Park S.L., Lee D.H., Yoo S.E., Jung Y.S. The effect of Na(+)/H(+) exchanger-1 inhibition by sabiporide on blood-brain barrier dysfunction after ischemia/hypoxia in vivo and in vitro. Brain Res. 2010, 1366:189-196.
    • (2010) Brain Res. , vol.1366 , pp. 189-196
    • Park, S.L.1    Lee, D.H.2    Yoo, S.E.3    Jung, Y.S.4
  • 230
  • 232
    • 0020082919 scopus 로고
    • Early proliferative changes in astrocytes in postischemic noninfarcted rat brain
    • Petito C.K., Babiak T. Early proliferative changes in astrocytes in postischemic noninfarcted rat brain. Ann. Neurol. 1982, 11:510-518.
    • (1982) Ann. Neurol. , vol.11 , pp. 510-518
    • Petito, C.K.1    Babiak, T.2
  • 235
    • 33845897638 scopus 로고    scopus 로고
    • Prolonged activation of ASIC1a and the time window for neuroprotection in cerebral ischaemia
    • Pignataro G., Simon R.P., Xiong Z.G. Prolonged activation of ASIC1a and the time window for neuroprotection in cerebral ischaemia. Brain 2007, 130:151-158.
    • (2007) Brain , vol.130 , pp. 151-158
    • Pignataro, G.1    Simon, R.P.2    Xiong, Z.G.3
  • 236
    • 4644243948 scopus 로고    scopus 로고
    • Selective regulation of acid-sensing ion channel 1 by serine proteases
    • Poirot O., Vukicevic M., Boesch A., Kellenberger S. Selective regulation of acid-sensing ion channel 1 by serine proteases. J. Biol. Chem. 2004, 279:38448-38457.
    • (2004) J. Biol. Chem. , vol.279 , pp. 38448-38457
    • Poirot, O.1    Vukicevic, M.2    Boesch, A.3    Kellenberger, S.4
  • 237
    • 35148835215 scopus 로고    scopus 로고
    • CNS-derived interleukin-4 is essential for the regulation of autoimmune inflammation and induces a state of alternative activation in microglial cells
    • Ponomarev E.D., Maresz K., Tan Y., Dittel B.N. CNS-derived interleukin-4 is essential for the regulation of autoimmune inflammation and induces a state of alternative activation in microglial cells. J. Neurosci. 2007, 27:10714-10721.
    • (2007) J. Neurosci. , vol.27 , pp. 10714-10721
    • Ponomarev, E.D.1    Maresz, K.2    Tan, Y.3    Dittel, B.N.4
  • 240
    • 84878107852 scopus 로고    scopus 로고
    • Multiple interacting cell death mechanisms in the mediation of excitotoxicity and ischemic brain damage: a challenge for neuroprotection
    • Puyal J., Ginet V., Clarke P.G. Multiple interacting cell death mechanisms in the mediation of excitotoxicity and ischemic brain damage: a challenge for neuroprotection. Prog. Neurobiol. 2013, 105:24-48.
    • (2013) Prog. Neurobiol. , vol.105 , pp. 24-48
    • Puyal, J.1    Ginet, V.2    Clarke, P.G.3
  • 241
  • 242
    • 0020040982 scopus 로고
    • Brain cortical fatty acids and phospholipids during and following complete and severe incomplete ischemia
    • Rehncrona S., Westerberg E., Akesson B., Siesjo B.K. Brain cortical fatty acids and phospholipids during and following complete and severe incomplete ischemia. J. Neurochem. 1982, 38:84-93.
    • (1982) J. Neurochem. , vol.38 , pp. 84-93
    • Rehncrona, S.1    Westerberg, E.2    Akesson, B.3    Siesjo, B.K.4
  • 243
    • 0036895240 scopus 로고    scopus 로고
    • Brain alkaline intracellular pH after neonatal encephalopathy
    • Robertson N.J., Cowan F.M., Cox I.J., Edwards A.D. Brain alkaline intracellular pH after neonatal encephalopathy. Ann. Neurol. 2002, 52:732-742.
    • (2002) Ann. Neurol. , vol.52 , pp. 732-742
    • Robertson, N.J.1    Cowan, F.M.2    Cox, I.J.3    Edwards, A.D.4
  • 244
    • 79751531393 scopus 로고    scopus 로고
    • Heart disease and stroke statistics - 2011 update: a report from the American Heart Association
    • Roger V.L., et al. Heart disease and stroke statistics - 2011 update: a report from the American Heart Association. Circulation 2011, 123:e18-e209.
    • (2011) Circulation , vol.123 , pp. e18-e209
    • Roger, V.L.1
  • 245
    • 0032767907 scopus 로고    scopus 로고
    • Sodium-hydrogen exchange and platelet function
    • Rosskopf D. Sodium-hydrogen exchange and platelet function. J. Thromb. Thrombolysis 1999, 8:15-24.
    • (1999) J. Thromb. Thrombolysis , vol.8 , pp. 15-24
    • Rosskopf, D.1
  • 246
    • 0022620257 scopus 로고
    • Glutamate and the pathophysiology of hypoxic-ischemic brain damage
    • Rothman S.M., Olney J.W. Glutamate and the pathophysiology of hypoxic-ischemic brain damage. Ann. Neurol. 1986, 19:105-111.
    • (1986) Ann. Neurol. , vol.19 , pp. 105-111
    • Rothman, S.M.1    Olney, J.W.2
  • 247
    • 0024814758 scopus 로고
    • Impaired cell volume regulation in Na(+)-H+ exchange-deficient mutants
    • Rotin D., Grinstein S. Impaired cell volume regulation in Na(+)-H+ exchange-deficient mutants. Am. J. Physiol. 1989, 257:C1158-C1165.
    • (1989) Am. J. Physiol. , vol.257 , pp. C1158-C1165
    • Rotin, D.1    Grinstein, S.2
  • 248
    • 0035131504 scopus 로고    scopus 로고
    • TRP-PLIK, a bifunctional protein with kinase and ion channel activities
    • Runnels L.W., Yue L., Clapham D.E. TRP-PLIK, a bifunctional protein with kinase and ion channel activities. Science 2001, 291:1043-1047.
    • (2001) Science , vol.291 , pp. 1043-1047
    • Runnels, L.W.1    Yue, L.2    Clapham, D.E.3
  • 249
    • 0036092076 scopus 로고    scopus 로고
    • The TRPM7 channel is inactivated by PIP(2) hydrolysis
    • Runnels L.W., Yue L., Clapham D.E. The TRPM7 channel is inactivated by PIP(2) hydrolysis. Nat. Cell Biol. 2002, 4:329-336.
    • (2002) Nat. Cell Biol. , vol.4 , pp. 329-336
    • Runnels, L.W.1    Yue, L.2    Clapham, D.E.3
  • 250
    • 0034720844 scopus 로고    scopus 로고
    • Cardioprotective effects of the Na(+)/H(+) exchange inhibitor cariporide in patients with acute anterior myocardial infarction undergoing direct PTCA
    • Rupprecht H.J., vom D.J., Terres W., Seyfarth K.M., Richardt G., Schultheibeta H.P., Buerke M., Sheehan F.H., Drexler H. Cardioprotective effects of the Na(+)/H(+) exchange inhibitor cariporide in patients with acute anterior myocardial infarction undergoing direct PTCA. Circulation 2000, 101:2902-2908.
    • (2000) Circulation , vol.101 , pp. 2902-2908
    • Rupprecht, H.J.1    vom, D.J.2    Terres, W.3    Seyfarth, K.M.4    Richardt, G.5    Schultheibeta, H.P.6    Buerke, M.7    Sheehan, F.H.8    Drexler, H.9
  • 251
    • 0037029138 scopus 로고    scopus 로고
    • Elongation factor-2 kinase and its newly discovered relatives
    • Ryazanov A.G. Elongation factor-2 kinase and its newly discovered relatives. FEBS Lett. 2002, 514:26-29.
    • (2002) FEBS Lett. , vol.514 , pp. 26-29
    • Ryazanov, A.G.1
  • 255
    • 77956398265 scopus 로고    scopus 로고
    • TRPM7 regulates quiescent/proliferative metabolic transitions in lymphocytes
    • Sahni J., Tamura R., Sweet I.R., Scharenberg A.M. TRPM7 regulates quiescent/proliferative metabolic transitions in lymphocytes. Cell Cycle 2010, 9:3565-3574.
    • (2010) Cell Cycle , vol.9 , pp. 3565-3574
    • Sahni, J.1    Tamura, R.2    Sweet, I.R.3    Scharenberg, A.M.4
  • 256
    • 80355143546 scopus 로고    scopus 로고
    • Microglial cell origin and phenotypes in health and disease
    • Saijo K., Glass C.K. Microglial cell origin and phenotypes in health and disease. Nat. Rev. Immunol. 2011, 11:775-787.
    • (2011) Nat. Rev. Immunol. , vol.11 , pp. 775-787
    • Saijo, K.1    Glass, C.K.2
  • 257
    • 11244269414 scopus 로고    scopus 로고
    • Analysis of the membrane topology of the acid-sensing ion channel 2a
    • Saugstad J.A., Roberts J.A., Dong J., Zeitouni S., Evans R.J. Analysis of the membrane topology of the acid-sensing ion channel 2a. J. Biol. Chem. 2004, 279:55514-55519.
    • (2004) J. Biol. Chem. , vol.279 , pp. 55514-55519
    • Saugstad, J.A.1    Roberts, J.A.2    Dong, J.3    Zeitouni, S.4    Evans, R.J.5
  • 259
    • 0030868480 scopus 로고    scopus 로고
    • The role of mitochondrial dysfunction and neuronal nitric oxide in animal models of neurodegenerative diseases
    • Schulz J.B., Matthews R.T., Klockgether T., Dichgans J., Beal M.F. The role of mitochondrial dysfunction and neuronal nitric oxide in animal models of neurodegenerative diseases. Mol. Cell. Biochem. 1997, 174:193-197.
    • (1997) Mol. Cell. Biochem. , vol.174 , pp. 193-197
    • Schulz, J.B.1    Matthews, R.T.2    Klockgether, T.3    Dichgans, J.4    Beal, M.F.5
  • 260
    • 0036673386 scopus 로고    scopus 로고
    • Lactate, glucose and energy metabolism in the ischemic brain
    • (review)
    • Schurr A. Lactate, glucose and energy metabolism in the ischemic brain. Int. J. Mol. Med. 2002, 10:131-136. (review).
    • (2002) Int. J. Mol. Med. , vol.10 , pp. 131-136
    • Schurr, A.1
  • 261
    • 0031731914 scopus 로고    scopus 로고
    • Brain anaerobic lactate production: a suicide note or a survival kit?
    • Schurr A., Rigor B.M. Brain anaerobic lactate production: a suicide note or a survival kit?. Dev. Neurosci. 1998, 20:348-357.
    • (1998) Dev. Neurosci. , vol.20 , pp. 348-357
    • Schurr, A.1    Rigor, B.M.2
  • 263
    • 70449623627 scopus 로고    scopus 로고
    • Dynorphin opioid peptides enhance acid-sensing ion channel 1a activity and acidosis-induced neuronal death
    • Sherwood T.W., Askwith C.C. Dynorphin opioid peptides enhance acid-sensing ion channel 1a activity and acidosis-induced neuronal death. J. Neurosci. 2009, 29:14371-14380.
    • (2009) J. Neurosci. , vol.29 , pp. 14371-14380
    • Sherwood, T.W.1    Askwith, C.C.2
  • 264
    • 79960024474 scopus 로고    scopus 로고
    • Heteromeric acid-sensing ion channels (ASICs) composed of ASIC2b and ASIC1a display novel channel properties and contribute to acidosis-induced neuronal death
    • Sherwood T.W., Lee K.G., Gormley M.G., Askwith C.C. Heteromeric acid-sensing ion channels (ASICs) composed of ASIC2b and ASIC1a display novel channel properties and contribute to acidosis-induced neuronal death. J. Neurosci. 2011, 31:9723-9734.
    • (2011) J. Neurosci. , vol.31 , pp. 9723-9734
    • Sherwood, T.W.1    Lee, K.G.2    Gormley, M.G.3    Askwith, C.C.4
  • 265
    • 80052647286 scopus 로고    scopus 로고
    • Role of sodium/hydrogen exchanger isoform 1 in microglial activation and proinflammatory responses in ischemic brains
    • Shi Y., Chanana V., Watters J.J., Ferrazzano P., Sun D. Role of sodium/hydrogen exchanger isoform 1 in microglial activation and proinflammatory responses in ischemic brains. J. Neurochem. 2011, 119:124-135.
    • (2011) J. Neurochem. , vol.119 , pp. 124-135
    • Shi, Y.1    Chanana, V.2    Watters, J.J.3    Ferrazzano, P.4    Sun, D.5
  • 267
    • 79960955504 scopus 로고    scopus 로고
    • Zinc: new clues to diverse roles in brain ischemia
    • Shuttleworth C.W., Weiss J.H. Zinc: new clues to diverse roles in brain ischemia. Trends Pharmacol. Sci. 2011, 32:480-486.
    • (2011) Trends Pharmacol. Sci. , vol.32 , pp. 480-486
    • Shuttleworth, C.W.1    Weiss, J.H.2
  • 268
    • 0024153902 scopus 로고
    • Acidosis and ischemic brain damage
    • Siesjo B.K. Acidosis and ischemic brain damage. Neurochem. Pathol. 1988, 9:31-88.
    • (1988) Neurochem. Pathol. , vol.9 , pp. 31-88
    • Siesjo, B.K.1
  • 269
    • 0026777223 scopus 로고
    • Pathophysiology and treatment of focal cerebral ischemia: Part I. Pathophysiology
    • Siesjo B.K. Pathophysiology and treatment of focal cerebral ischemia: Part I. Pathophysiology. J. Neurosurg. 1992, 77:169-184.
    • (1992) J. Neurosurg. , vol.77 , pp. 169-184
    • Siesjo, B.K.1
  • 271
    • 0021743001 scopus 로고
    • Blockade of N-methyl-d-aspartate receptors may protect against ischemic damage in the brain
    • Simon R.P., Swan J.H., Griffiths T., Meldrum B.S. Blockade of N-methyl-d-aspartate receptors may protect against ischemic damage in the brain. Science 1984, 226:850-852.
    • (1984) Science , vol.226 , pp. 850-852
    • Simon, R.P.1    Swan, J.H.2    Griffiths, T.3    Meldrum, B.S.4
  • 272
    • 17644413778 scopus 로고    scopus 로고
    • Impaired regulation of pH homeostasis by oxidative stress in rat brain capillary endothelial cells
    • Sipos H., Torocsik B., Tretter L., Adam-Vizi V. Impaired regulation of pH homeostasis by oxidative stress in rat brain capillary endothelial cells. Cell. Mol. Neurobiol. 2005, 25:141-151.
    • (2005) Cell. Mol. Neurobiol. , vol.25 , pp. 141-151
    • Sipos, H.1    Torocsik, B.2    Tretter, L.3    Adam-Vizi, V.4
  • 273
    • 0344305593 scopus 로고    scopus 로고
    • Chronic hyperalgesia induced by repeated acid injections in muscle is abolished by the loss of ASIC3, but not ASIC1
    • Sluka K.A., Price M.P., Breese N.M., Stucky C.L., Wemmie J.A., Welsh M.J. Chronic hyperalgesia induced by repeated acid injections in muscle is abolished by the loss of ASIC3, but not ASIC1. Pain 2003, 106:229-239.
    • (2003) Pain , vol.106 , pp. 229-239
    • Sluka, K.A.1    Price, M.P.2    Breese, N.M.3    Stucky, C.L.4    Wemmie, J.A.5    Welsh, M.J.6
  • 274
    • 33847369550 scopus 로고    scopus 로고
    • Arachidonic acid potentiates acid-sensing ion channels in rat sensory neurons by a direct action
    • Smith E.S., Cadiou H., McNaughton P.A. Arachidonic acid potentiates acid-sensing ion channels in rat sensory neurons by a direct action. Neuroscience 2007, 145:686-698.
    • (2007) Neuroscience , vol.145 , pp. 686-698
    • Smith, E.S.1    Cadiou, H.2    McNaughton, P.A.3
  • 277
    • 0021163253 scopus 로고
    • Acidification of interstitial fluid in hippocampal formation caused by seizures and by spreading depression
    • Somjen G.G. Acidification of interstitial fluid in hippocampal formation caused by seizures and by spreading depression. Brain Res. 1984, 311:186-188.
    • (1984) Brain Res. , vol.311 , pp. 186-188
    • Somjen, G.G.1
  • 278
    • 42049100585 scopus 로고    scopus 로고
    • Downregulation of renal TRPM7 and increased inflammation and fibrosis in aldosterone-infused mice: effects of magnesium
    • Sontia B., Montezano A.C., Paravicini T., Tabet F., Touyz R.M. Downregulation of renal TRPM7 and increased inflammation and fibrosis in aldosterone-infused mice: effects of magnesium. Hypertension 2008, 51:915-921.
    • (2008) Hypertension , vol.51 , pp. 915-921
    • Sontia, B.1    Montezano, A.C.2    Paravicini, T.3    Tabet, F.4    Touyz, R.M.5
  • 280
    • 4344706372 scopus 로고    scopus 로고
    • Functional plasticity of macrophages: reversible adaptation to changing microenvironments
    • Stout R.D., Suttles J. Functional plasticity of macrophages: reversible adaptation to changing microenvironments. J. Leukoc. Biol. 2004, 76:509-513.
    • (2004) J. Leukoc. Biol. , vol.76 , pp. 509-513
    • Stout, R.D.1    Suttles, J.2
  • 283
    • 84891418938 scopus 로고    scopus 로고
    • Role of TRPM7 channels in hyperglycemia-mediated injury of vascular endothelial cells
    • Sun H., Leng T., Zeng Z., Gao X., Inoue K., Xiong Z.G. Role of TRPM7 channels in hyperglycemia-mediated injury of vascular endothelial cells. PLoS ONE 2013, 8:e79540.
    • (2013) PLoS ONE , vol.8
    • Sun, H.1    Leng, T.2    Zeng, Z.3    Gao, X.4    Inoue, K.5    Xiong, Z.G.6
  • 287
    • 0037008460 scopus 로고    scopus 로고
    • SM-20220, a Na(+)/H(+) exchanger inhibitor: effects on ischemic brain damage through edema and neutrophil accumulation in a rat middle cerebral artery occlusion model
    • Suzuki Y., Matsumoto Y., Ikeda Y., Kondo K., Ohashi N., Umemura K. SM-20220, a Na(+)/H(+) exchanger inhibitor: effects on ischemic brain damage through edema and neutrophil accumulation in a rat middle cerebral artery occlusion model. Brain Res. 2002, 945:242-248.
    • (2002) Brain Res. , vol.945 , pp. 242-248
    • Suzuki, Y.1    Matsumoto, Y.2    Ikeda, Y.3    Kondo, K.4    Ohashi, N.5    Umemura, K.6
  • 288
    • 84882289771 scopus 로고    scopus 로고
    • Coupling of proton binding in extracellular domain to channel gating in acid-sensing ion channel
    • Swain S.M., Bera A.K. Coupling of proton binding in extracellular domain to channel gating in acid-sensing ion channel. J. Mol. Neurosci. 2013, 51:199-207.
    • (2013) J. Mol. Neurosci. , vol.51 , pp. 199-207
    • Swain, S.M.1    Bera, A.K.2
  • 289
    • 0028906351 scopus 로고
    • Acidosis causes failure of astrocyte glutamate uptake during hypoxia
    • Swanson R.A., Farrell K., Simon R.P. Acidosis causes failure of astrocyte glutamate uptake during hypoxia. J. Cereb. Blood Flow Metab. 1995, 15:417-424.
    • (1995) J. Cereb. Blood Flow Metab. , vol.15 , pp. 417-424
    • Swanson, R.A.1    Farrell, K.2    Simon, R.P.3
  • 290
    • 0031239618 scopus 로고    scopus 로고
    • Astrocyte energetics, function, and death under conditions of incomplete ischemia: a mechanism of glial death in the penumbra
    • Swanson R.A., Farrell K., Stein B.A. Astrocyte energetics, function, and death under conditions of incomplete ischemia: a mechanism of glial death in the penumbra. Glia 1997, 21:142-153.
    • (1997) Glia , vol.21 , pp. 142-153
    • Swanson, R.A.1    Farrell, K.2    Stein, B.A.3
  • 291
    • 84875981269 scopus 로고    scopus 로고
    • Amiloride but not memantine reduces neurodegeneration, seizures and myoclonic jerks in rats with cardiac arrest-induced global cerebral hypoxia and reperfusion
    • Tai K.K., Truong D.D. Amiloride but not memantine reduces neurodegeneration, seizures and myoclonic jerks in rats with cardiac arrest-induced global cerebral hypoxia and reperfusion. PLoS ONE 2013, 8:e60309.
    • (2013) PLoS ONE , vol.8
    • Tai, K.K.1    Truong, D.D.2
  • 292
    • 0030029482 scopus 로고    scopus 로고
    • Modulation of neuronal function by intracellular pH
    • Takahashi K.I., Copenhagen D.R. Modulation of neuronal function by intracellular pH. Neurosci. Res. 1996, 24:109-116.
    • (1996) Neurosci. Res. , vol.24 , pp. 109-116
    • Takahashi, K.I.1    Copenhagen, D.R.2
  • 293
    • 12144283981 scopus 로고    scopus 로고
    • Morphine-induced chemotaxis and brain-derived neurotrophic factor expression in microglia
    • Takayama N., Ueda H. Morphine-induced chemotaxis and brain-derived neurotrophic factor expression in microglia. J. Neurosci. 2005, 25:430-435.
    • (2005) J. Neurosci. , vol.25 , pp. 430-435
    • Takayama, N.1    Ueda, H.2
  • 294
    • 0034687597 scopus 로고    scopus 로고
    • Inhibition of the sodium-hydrogen exchanger with cariporide to prevent myocardial infarction in high-risk ischemic situations. Main results of the GUARDIAN trial. Guard during ischemia against necrosis (GUARDIAN) Investigators
    • Theroux P., Chaitman B.R., Danchin N., Erhardt L., Meinertz T., Schroeder J.S., Tognoni G., White H.D., Willerson J.T., Jessel A. Inhibition of the sodium-hydrogen exchanger with cariporide to prevent myocardial infarction in high-risk ischemic situations. Main results of the GUARDIAN trial. Guard during ischemia against necrosis (GUARDIAN) Investigators. Circulation 2000, 102:3032-3038.
    • (2000) Circulation , vol.102 , pp. 3032-3038
    • Theroux, P.1    Chaitman, B.R.2    Danchin, N.3    Erhardt, L.4    Meinertz, T.5    Schroeder, J.S.6    Tognoni, G.7    White, H.D.8    Willerson, J.T.9    Jessel, A.10
  • 296
    • 0032541338 scopus 로고    scopus 로고
    • P160ROCK mediates RhoA activation of Na-H exchange
    • Tominaga T., Ishizaki T., Narumiya S., Barber D.L. p160ROCK mediates RhoA activation of Na-H exchange. EMBO J. 1998, 17:4712-4722.
    • (1998) EMBO J. , vol.17 , pp. 4712-4722
    • Tominaga, T.1    Ishizaki, T.2    Narumiya, S.3    Barber, D.L.4
  • 297
    • 33644840378 scopus 로고    scopus 로고
    • Differential regulation of transient receptor potential melastatin 6 and 7 cation channels by ANG II in vascular smooth muscle cells from spontaneously hypertensive rats
    • Touyz R.M., He Y., Montezano A.C., Yao G., Chubanov V., Gudermann T., Callera G.E. Differential regulation of transient receptor potential melastatin 6 and 7 cation channels by ANG II in vascular smooth muscle cells from spontaneously hypertensive rats. Am. J. Physiol. Regul. Integr. Comp. Physiol. 2006, 290:R73-R78.
    • (2006) Am. J. Physiol. Regul. Integr. Comp. Physiol. , vol.290 , pp. R73-R78
    • Touyz, R.M.1    He, Y.2    Montezano, A.C.3    Yao, G.4    Chubanov, V.5    Gudermann, T.6    Callera, G.E.7
  • 298
    • 0036802854 scopus 로고    scopus 로고
    • Amiloride-blockable acid-sensing ion channels are leading acid sensors expressed in human nociceptors
    • Ugawa S., Ueda T., Ishida Y., Nishigaki M., Shibata Y., Shimada S. Amiloride-blockable acid-sensing ion channels are leading acid sensors expressed in human nociceptors. J. Clin. Invest. 2002, 110:1185-1190.
    • (2002) J. Clin. Invest. , vol.110 , pp. 1185-1190
    • Ugawa, S.1    Ueda, T.2    Ishida, Y.3    Nishigaki, M.4    Shibata, Y.5    Shimada, S.6
  • 300
    • 34547768089 scopus 로고    scopus 로고
    • Clinical practice: acute ischemic stroke
    • van der Worp H.B., van Gijn J. Clinical practice: acute ischemic stroke. N. Engl. J. Med. 2007, 357:572-579.
    • (2007) N. Engl. J. Med. , vol.357 , pp. 572-579
    • van der Worp, H.B.1    van Gijn, J.2
  • 301
    • 68649111832 scopus 로고    scopus 로고
    • Alternative activation of macrophages: immune function and cellular biology
    • Varin A., Gordon S. Alternative activation of macrophages: immune function and cellular biology. Immunobiology 2009, 214:630-641.
    • (2009) Immunobiology , vol.214 , pp. 630-641
    • Varin, A.1    Gordon, S.2
  • 302
    • 0032757391 scopus 로고    scopus 로고
    • Proton-gated ion channels in cultured mouse cortical neurons
    • Varming T. Proton-gated ion channels in cultured mouse cortical neurons. Neuropharmacology 1999, 38:1875-1881.
    • (1999) Neuropharmacology , vol.38 , pp. 1875-1881
    • Varming, T.1
  • 306
    • 0034065040 scopus 로고    scopus 로고
    • Serine protease inhibitors: novel therapeutic targets for stroke?
    • Vivien D., Buisson A. Serine protease inhibitors: novel therapeutic targets for stroke?. J. Cereb. Blood Flow Metab. 2000, 20:755-764.
    • (2000) J. Cereb. Blood Flow Metab. , vol.20 , pp. 755-764
    • Vivien, D.1    Buisson, A.2
  • 307
    • 0035887733 scopus 로고    scopus 로고
    • Nonsteroid anti-inflammatory drugs inhibit both the activity and the inflammation-induced expression of acid-sensing ion channels in nociceptors
    • Voilley N., de Weille J., Mamet J., Lazdunski M. Nonsteroid anti-inflammatory drugs inhibit both the activity and the inflammation-induced expression of acid-sensing ion channels in nociceptors. J. Neurosci. 2001, 21:8026-8033.
    • (2001) J. Neurosci. , vol.21 , pp. 8026-8033
    • Voilley, N.1    de Weille, J.2    Mamet, J.3    Lazdunski, M.4
  • 308
    • 33644861783 scopus 로고    scopus 로고
    • Trypsin cleaves acid-sensing ion channel 1a in a domain that is critical for channel gating
    • Vukicevic M., Weder G., Boillat A., Boesch A., Kellenberger S. Trypsin cleaves acid-sensing ion channel 1a in a domain that is critical for channel gating. J. Biol. Chem. 2006, 281:714-722.
    • (2006) J. Biol. Chem. , vol.281 , pp. 714-722
    • Vukicevic, M.1    Weder, G.2    Boillat, A.3    Boesch, A.4    Kellenberger, S.5
  • 310
    • 0034731362 scopus 로고    scopus 로고
    • Second mutations rescue point mutant of the Na(+)/H(+) exchanger NHE1 showing defective surface expression
    • Wakabayashi S., Pang T., Su X., Shigekawa M. Second mutations rescue point mutant of the Na(+)/H(+) exchanger NHE1 showing defective surface expression. FEBS Lett. 2000, 487:257-261.
    • (2000) FEBS Lett. , vol.487 , pp. 257-261
    • Wakabayashi, S.1    Pang, T.2    Su, X.3    Shigekawa, M.4
  • 311
    • 77649235024 scopus 로고    scopus 로고
    • ASIC1 and ASIC3 play different roles in the development of hyperalgesia after inflammatory muscle injury
    • Walder R.Y., Rasmussen L.A., Rainier J.D., Light A.R., Wemmie J.A., Sluka K.A. ASIC1 and ASIC3 play different roles in the development of hyperalgesia after inflammatory muscle injury. J. Pain 2010, 11:210-218.
    • (2010) J. Pain , vol.11 , pp. 210-218
    • Walder, R.Y.1    Rasmussen, L.A.2    Rainier, J.D.3    Light, A.R.4    Wemmie, J.A.5    Sluka, K.A.6
  • 317
    • 3142765798 scopus 로고
    • PH of cerebral cortex during induced convulsions
    • Wang R.I., Sonnenschein R.R. PH of cerebral cortex during induced convulsions. J. Neurophysiol. 1955, 18:130-137.
    • (1955) J. Neurophysiol. , vol.18 , pp. 130-137
    • Wang, R.I.1    Sonnenschein, R.R.2
  • 318
    • 33646357923 scopus 로고    scopus 로고
    • Calcium-permeable acid-sensing ion channel is a molecular target of the neurotoxic metal ion lead
    • Wang W., Duan B., Xu H., Xu L., Xu T.L. Calcium-permeable acid-sensing ion channel is a molecular target of the neurotoxic metal ion lead. J. Biol. Chem. 2006, 281:2497-2505.
    • (2006) J. Biol. Chem. , vol.281 , pp. 2497-2505
    • Wang, W.1    Duan, B.2    Xu, H.3    Xu, L.4    Xu, T.L.5
  • 319
    • 54049146994 scopus 로고    scopus 로고
    • + exchanger isoform 1 attenuates apoptosis and mitochondrial damage following transient focal cerebral ischemia
    • + exchanger isoform 1 attenuates apoptosis and mitochondrial damage following transient focal cerebral ischemia. Eur. J. Neurosci. 2008, 28:51-61.
    • (2008) Eur. J. Neurosci. , vol.28 , pp. 51-61
    • Wang, Y.1    Luo, J.2    Chen, X.3    Chen, H.4    Cramer, S.W.5    Sun, D.6
  • 320
    • 84862629039 scopus 로고    scopus 로고
    • Recombinant tissue plasminogen activator for acute ischaemic stroke: an updated systematic review and meta-analysis
    • Wardlaw J.M., Murray V., Berge E., del Zoppo G., Sandercock P., Lindley R.L., Cohen G. Recombinant tissue plasminogen activator for acute ischaemic stroke: an updated systematic review and meta-analysis. Lancet 2012, 379:2364-2372.
    • (2012) Lancet , vol.379 , pp. 2364-2372
    • Wardlaw, J.M.1    Murray, V.2    Berge, E.3    del Zoppo, G.4    Sandercock, P.5    Lindley, R.L.6    Cohen, G.7
  • 321
    • 0038384013 scopus 로고    scopus 로고
    • Acid-sensing ion channel 1 is localized in brain regions with high synaptic density and contributes to fear conditioning
    • Wemmie J.A., Askwith C.C., Lamani E., Cassell M.D., Freeman J.H., Welsh M.J. Acid-sensing ion channel 1 is localized in brain regions with high synaptic density and contributes to fear conditioning. J. Neurosci. 2003, 23:5496-5502.
    • (2003) J. Neurosci. , vol.23 , pp. 5496-5502
    • Wemmie, J.A.1    Askwith, C.C.2    Lamani, E.3    Cassell, M.D.4    Freeman, J.H.5    Welsh, M.J.6
  • 323
    • 33748797928 scopus 로고    scopus 로고
    • Acid-sensing ion channels: advances, questions and therapeutic opportunities
    • Wemmie J.A., Price M.P., Welsh M.J. Acid-sensing ion channels: advances, questions and therapeutic opportunities. Trends Neurosci. 2006, 29:578-586.
    • (2006) Trends Neurosci. , vol.29 , pp. 578-586
    • Wemmie, J.A.1    Price, M.P.2    Welsh, M.J.3
  • 326
    • 77951153667 scopus 로고    scopus 로고
    • High glucose-induced oxidative stress increases transient receptor potential channel expression in human monocytes
    • Wuensch T., Thilo F., Krueger K., Scholze A., Ristow M., Tepel M. High glucose-induced oxidative stress increases transient receptor potential channel expression in human monocytes. Diabetes 2010, 59:844-849.
    • (2010) Diabetes , vol.59 , pp. 844-849
    • Wuensch, T.1    Thilo, F.2    Krueger, K.3    Scholze, A.4    Ristow, M.5    Tepel, M.6
  • 327
    • 35748972654 scopus 로고    scopus 로고
    • Functional transient receptor potential melastatin 7 channels are critical for human mast cell survival
    • Wykes R.C., Lee M., Duffy S.M., Yang W., Seward E.P., Bradding P. Functional transient receptor potential melastatin 7 channels are critical for human mast cell survival. J. Immunol. 2007, 179:4045-4052.
    • (2007) J. Immunol. , vol.179 , pp. 4045-4052
    • Wykes, R.C.1    Lee, M.2    Duffy, S.M.3    Yang, W.4    Seward, E.P.5    Bradding, P.6
  • 331
    • 79958278118 scopus 로고    scopus 로고
    • Neuroprotective effect of acid-sensing ion channel inhibitor psalmotoxin-1 after hypoxia-ischemia in newborn piglet striatum
    • Yang Z.J., Ni X., Carter E.L., Kibler K., Martin L.J., Koehler R.C. Neuroprotective effect of acid-sensing ion channel inhibitor psalmotoxin-1 after hypoxia-ischemia in newborn piglet striatum. Neurobiol. Dis. 2011, 43:446-454.
    • (2011) Neurobiol. Dis. , vol.43 , pp. 446-454
    • Yang, Z.J.1    Ni, X.2    Carter, E.L.3    Kibler, K.4    Martin, L.J.5    Koehler, R.C.6
  • 332
    • 0032750290 scopus 로고    scopus 로고
    • Intracellular pH regulation of CA1 neurons in Na(+)/H(+) isoform 1 mutant mice
    • Yao H., Ma E., Gu X.Q., Haddad G.G. Intracellular pH regulation of CA1 neurons in Na(+)/H(+) isoform 1 mutant mice. J. Clin. Invest. 1999, 104:637-645.
    • (1999) J. Clin. Invest. , vol.104 , pp. 637-645
    • Yao, H.1    Ma, E.2    Gu, X.Q.3    Haddad, G.G.4
  • 333
    • 79952341316 scopus 로고    scopus 로고
    • 2+-sensitive Socs3a signaling in development and cancer
    • 2+-sensitive Socs3a signaling in development and cancer. Dis. Model Mech. 2011, 4:240-254.
    • (2011) Dis. Model Mech. , vol.4 , pp. 240-254
    • Yee, N.S.1    Zhou, W.2    Liang, I.C.3
  • 334
    • 69949172891 scopus 로고    scopus 로고
    • Pericyte contraction induced by oxidative-nitrative stress impairs capillary reflow despite successful opening of an occluded cerebral artery
    • Yemisci M., Gursoy-Ozdemir Y., Vural A., Can A., Topalkara K., Dalkara T. Pericyte contraction induced by oxidative-nitrative stress impairs capillary reflow despite successful opening of an occluded cerebral artery. Nat. Med. 2009, 15:1031-1037.
    • (2009) Nat. Med. , vol.15 , pp. 1031-1037
    • Yemisci, M.1    Gursoy-Ozdemir, Y.2    Vural, A.3    Can, A.4    Topalkara, K.5    Dalkara, T.6
  • 335
    • 77957088682 scopus 로고    scopus 로고
    • Microglial activation in stroke: therapeutic targets
    • Yenari M.A., Kauppinen T.M., Swanson R.A. Microglial activation in stroke: therapeutic targets. Neurotherapeutics 2010, 7(4):378-391.
    • (2010) Neurotherapeutics , vol.7 , Issue.4 , pp. 378-391
    • Yenari, M.A.1    Kauppinen, T.M.2    Swanson, R.A.3
  • 337
  • 338
    • 0032880761 scopus 로고    scopus 로고
    • Acidosis potentiates oxidative neuronal death by multiple mechanisms
    • Ying W., Han S.K., Miller J.W., Swanson R.A. Acidosis potentiates oxidative neuronal death by multiple mechanisms. J. Neurochem. 1999, 73:1549-1556.
    • (1999) J. Neurochem. , vol.73 , pp. 1549-1556
    • Ying, W.1    Han, S.K.2    Miller, J.W.3    Swanson, R.A.4
  • 339
    • 79958765852 scopus 로고    scopus 로고
    • Dysregulation of renal transient receptor potential melastatin 6/7 but not paracellin-1 in aldosterone-induced hypertension and kidney damage in a model of hereditary hypomagnesemia
    • Yogi A., Callera G.E., O'Connor S.E., He Y., Correa J.W., Tostes R.C., Mazur A., Touyz R.M. Dysregulation of renal transient receptor potential melastatin 6/7 but not paracellin-1 in aldosterone-induced hypertension and kidney damage in a model of hereditary hypomagnesemia. J. Hypertens. 2011, 29:1400-1410.
    • (2011) J. Hypertens. , vol.29 , pp. 1400-1410
    • Yogi, A.1    Callera, G.E.2    O'Connor, S.E.3    He, Y.4    Correa, J.W.5    Tostes, R.C.6    Mazur, A.7    Touyz, R.M.8
  • 344
    • 84876258536 scopus 로고    scopus 로고
    • Molecular mechanism of constitutive endocytosis of acid-sensing ion channel 1a and its protective function in acidosis-induced neuronal death
    • Zeng W.Z., Liu D.S., Duan B., Song X.L., Wang X., Wei D., Jiang W., Zhu M.X., Li Y., Xu T.L. Molecular mechanism of constitutive endocytosis of acid-sensing ion channel 1a and its protective function in acidosis-induced neuronal death. J. Neurosci. 2013, 33:7066-7078.
    • (2013) J. Neurosci. , vol.33 , pp. 7066-7078
    • Zeng, W.Z.1    Liu, D.S.2    Duan, B.3    Song, X.L.4    Wang, X.5    Wei, D.6    Jiang, W.7    Zhu, M.X.8    Li, Y.9    Xu, T.L.10
  • 345
    • 0035890319 scopus 로고    scopus 로고
    • The Na(+)/H(+) exchange inhibitor eniporide as an adjunct to early reperfusion therapy for acute myocardial infarction: results of the evaluation of the safety and cardioprotective effects of eniporide in acute myocardial infarction (ESCAMI) trial
    • Zeymer U., Suryapranata H., Monassier J.P., Opolski G., Davies J., Rasmanis G., Linssen G., Tebbe U., Schroder R., Tiemann R., Machnig T., Neuhaus K.L. The Na(+)/H(+) exchange inhibitor eniporide as an adjunct to early reperfusion therapy for acute myocardial infarction: results of the evaluation of the safety and cardioprotective effects of eniporide in acute myocardial infarction (ESCAMI) trial. J. Am. Coll. Cardiol. 2001, 38:1644-1650.
    • (2001) J. Am. Coll. Cardiol. , vol.38 , pp. 1644-1650
    • Zeymer, U.1    Suryapranata, H.2    Monassier, J.P.3    Opolski, G.4    Davies, J.5    Rasmanis, G.6    Linssen, G.7    Tebbe, U.8    Schroder, R.9    Tiemann, R.10    Machnig, T.11    Neuhaus, K.L.12
  • 346
    • 33750840489 scopus 로고    scopus 로고
    • Acid-sensing ion channel 1a is a postsynaptic proton receptor that affects the density of dendritic spines
    • Zha X.M., Wemmie J.A., Green S.H., Welsh M.J. Acid-sensing ion channel 1a is a postsynaptic proton receptor that affects the density of dendritic spines. Proc. Natl. Acad. Sci. U. S. A. 2006, 103:16556-16561.
    • (2006) Proc. Natl. Acad. Sci. U. S. A. , vol.103 , pp. 16556-16561
    • Zha, X.M.1    Wemmie, J.A.2    Green, S.H.3    Welsh, M.J.4
  • 347
    • 79958011245 scopus 로고    scopus 로고
    • Hypoxia induces an increase in intracellular magnesium via transient receptor potential melastatin 7 (TRPM7) channels in rat hippocampal neurons in vitro
    • Zhang J., Zhao F., Zhao Y., Wang J., Pei L., Sun N., Shi J. Hypoxia induces an increase in intracellular magnesium via transient receptor potential melastatin 7 (TRPM7) channels in rat hippocampal neurons in vitro. J. Biol. Chem. 2011, 286:20194-20207.
    • (2011) J. Biol. Chem. , vol.286 , pp. 20194-20207
    • Zhang, J.1    Zhao, F.2    Zhao, Y.3    Wang, J.4    Pei, L.5    Sun, N.6    Shi, J.7
  • 349
    • 84864281309 scopus 로고    scopus 로고
    • The neurovascular unit and combination treatment strategies for stroke
    • Zhang L., Zhang Z.G., Chopp M. The neurovascular unit and combination treatment strategies for stroke. Trends Pharmacol. Sci. 2012, 33:415-422.
    • (2012) Trends Pharmacol. Sci. , vol.33 , pp. 415-422
    • Zhang, L.1    Zhang, Z.G.2    Chopp, M.3
  • 350
    • 26444613280 scopus 로고    scopus 로고
    • Edaravone reduces early accumulation of oxidative products and sequential inflammatory responses after transient focal ischemia in mice brain
    • Zhang N., Komine-Kobayashi M., Tanaka R., Liu M., Mizuno Y., Urabe T. Edaravone reduces early accumulation of oxidative products and sequential inflammatory responses after transient focal ischemia in mice brain. Stroke 2005, 36(10):2220-2225.
    • (2005) Stroke , vol.36 , Issue.10 , pp. 2220-2225
    • Zhang, N.1    Komine-Kobayashi, M.2    Tanaka, R.3    Liu, M.4    Mizuno, Y.5    Urabe, T.6
  • 352
    • 84867743483 scopus 로고    scopus 로고
    • Upregulation of TRPM7 channels by angiotensin II triggers phenotypic switching of vascular smooth muscle cells of ascending aorta
    • Zhang Z., Wang M., Fan X.H., Chen J.H., Guan Y.Y., Tang Y.B. Upregulation of TRPM7 channels by angiotensin II triggers phenotypic switching of vascular smooth muscle cells of ascending aorta. Circ. Res. 2012, 111:1137-1146.
    • (2012) Circ. Res. , vol.111 , pp. 1137-1146
    • Zhang, Z.1    Wang, M.2    Fan, X.H.3    Chen, J.H.4    Guan, Y.Y.5    Tang, Y.B.6
  • 353
    • 77950192239 scopus 로고    scopus 로고
    • Pharmacology of transient receptor potential melastatin channels in the vasculature
    • Zholos A. Pharmacology of transient receptor potential melastatin channels in the vasculature. Br. J. Pharmacol. 2010, 159:1559-1571.
    • (2010) Br. J. Pharmacol. , vol.159 , pp. 1559-1571
    • Zholos, A.1
  • 354
    • 0028912869 scopus 로고
    • Surface charge and calcium channel saturation in bullfrog sympathetic neurons
    • Zhou W., Jones S.W. Surface charge and calcium channel saturation in bullfrog sympathetic neurons. J. Gen. Physiol. 1995, 105:441-462.
    • (1995) J. Gen. Physiol. , vol.105 , pp. 441-462
    • Zhou, W.1    Jones, S.W.2
  • 357
    • 80655144731 scopus 로고    scopus 로고
    • Inhibits cell proliferation through magnesium-dependent block of transient receptor potential melastatin 7 (TRPM7) channels
    • Zierler S., Yao G., Zhang Z., Kuo W.C., Porzgen P., Penner R., Horgen F.D., Fleig A., Waixenicin A. inhibits cell proliferation through magnesium-dependent block of transient receptor potential melastatin 7 (TRPM7) channels. J. Biol. Chem. 2011, 286:39328-39335.
    • (2011) J. Biol. Chem. , vol.286 , pp. 39328-39335
    • Zierler, S.1    Yao, G.2    Zhang, Z.3    Kuo, W.C.4    Porzgen, P.5    Penner, R.6    Horgen, F.D.7    Fleig, A.8    Waixenicin, A.9


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.