A TRPM7 variant shows altered sensitivity to magnesium that may contribute to the pathogenesis of two Guamanian neurodegenerative disorders

Proceedings of the National Academy of Sciences of the United States of America

Volumn 102, Issue 32, 2005, Pages 11510-11515

  Hermosura, Meredith C ^a   Nayakanti, Hannah ^a   Dorovkov, Maxim V ^c   Calderon, Fernanda R ^a   Ryazanov, Alexey G ^c   Haymer, David S ^b   Garruto, Ralph M ^d  

^a UNIVERSITY OF HAWAII   (United States)

^b UNIVERSITY OF HAWAII   (United States)

^c RUTGERS ROBERT WOOD JOHNSON MEDICAL SCHOOL   (United States)

^d BINGHAMTON UNIVERSITY   (United States)

Author keywords

Amyotrophic lateral sclerosis; Calcium; Gene environment interactions; Parkinsonism dementia; Phosphorylation

Indexed keywords

CALCIUM ION; GENOMIC DNA; MAGNESIUM ION; PHOSPHOAMINO ACID; PROTEIN KINASE; RECOMBINANT PROTEIN; TRANSIENT RECEPTOR POTENTIAL CHANNEL; TRANSIENT RECEPTOR POTENTIAL MELASTATIN 7; UNCLASSIFIED DRUG;

AMYOTROPHIC LATERAL SCLEROSIS; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; DEGENERATIVE DISEASE; DEMENTIA; ENZYME ACTIVITY; ENZYME ASSAY; ENZYME PHOSPHORYLATION; FEMALE; GENE MUTATION; HUMAN; HUMAN CELL; MALE; NEUROLOGIC DISEASE; NEUROPATHOLOGY; NONHUMAN; NUCLEOTIDE SEQUENCE; PARKINSON DISEASE; PRIORITY JOURNAL; PROTEIN PURIFICATION;

AMINO ACID SEQUENCE; AMYOTROPHIC LATERAL SCLEROSIS; BASE SEQUENCE; CELL LINE; ELECTROPHYSIOLOGY; ENVIRONMENT; FLUORESCENT ANTIBODY TECHNIQUE; GENETIC PREDISPOSITION TO DISEASE; GUAM; HUMANS; MAGNESIUM; MOLECULAR SEQUENCE DATA; MUTATION, MISSENSE; PARKINSONIAN DISORDERS; SEQUENCE ANALYSIS, DNA; TRPM CATION CHANNELS;

EID: 23844451376     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.0505149102     Document Type: Article

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