Prolonged activation of ASIC1a and the time window for neuroprotection in cerebral ischaemia

Brain

Volumn 130, Issue 1, 2007, Pages 151-158

  Pignataro, Giuseppe ^a   Simon, Roger P ^a   Xiong, Zhi Gang ^a  

^a LEGACY RESEARCH   (United States)

Author keywords

Acid sensing ion channels; Acidosis; Ischaemia; Neuroprotection

Indexed keywords

ACID SENSING ION CHANNEL; BICARBONATE; MEMANTINE; NEUROPROTECTIVE AGENT; PSALMOTOXIN; UNCLASSIFIED DRUG;

ACIDOSIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN ISCHEMIA; CONTROLLED STUDY; MALE; MIDDLE CEREBRAL ARTERY OCCLUSION; MOUSE; NEUROPROTECTION; NONHUMAN; PH; PRIORITY JOURNAL; STROKE;

ACIDOSIS; ANIMALS; BRAIN; BRAIN ISCHEMIA; CEREBRAL CORTEX; CEREBRAL VENTRICLES; CEREBROVASCULAR CIRCULATION; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; HYDROGEN-ION CONCENTRATION; INFARCTION, MIDDLE CEREBRAL ARTERY; MALE; MEMBRANE PROTEINS; MICE; MICE, INBRED C57BL; N-METHYLASPARTATE; NERVE TISSUE PROTEINS; NEUROPROTECTIVE AGENTS; SODIUM BICARBONATE; SODIUM CHANNELS; SPIDER VENOMS; TIME FACTORS;

EID: 33845897638     PISSN: 00068950     EISSN: 14602156     Source Type: Journal    
DOI: 10.1093/brain/awl325     Document Type: Article

References (39)

1. Allen NJ, Attwell D. Modulation of ASIC channels in rat cerebellar Purkinje neurons by ischaemia-related signals. J Physiol 2002; 543: 521-9.
2. Astrup J, Symon L, Branston NM, Lassen NA. Cortical evoked potential and extracellular K+ and H+ at critical levels of brain ischemia. Stroke 1977; 8: 51-7.
3. Back T, Hoehn M, Mies G, Busch E, Schmitz B, Kohno K, et al. Penumbral tissue alkalosis in focal cerebral ischemia: relationship to energy metabolism, blood flow, and steady potential. Ann Neurol 2000; 47: 485-92.
4. Bano D, Young KW, Guerin CJ, Lefeuvre R, Rothwell NJ, Naldini L, et al. Cleavage of the plasma membrane Na+/Ca2+ exchanger in excitotoxicity. Cell 2005; 120: 275-85.
5. Bederson JB, Pitts LH, Germano SM, Nishimura MC, Davis RL, Bartkowski HM. Evaluation of 2,3,5-triphenyltetrazolium chloride as a stain for detection and quantification of experimental cerebral infarction in rats. Stroke 1986; 17: 1304-8.
6. Benveniste M, Dingledine R. Limiting stroke-induced damage by targeting an acid channel. N Engl J Med 2005; 352: 85-6.
7. Capsoni S, Giannotta S, Cattaneo A. Nerve growth factor and galantamine ameliorate early signs of neurodegeneration in anti-nerve growth factor mice. Proc Natl Acad Sci USA 2002; 99: 12432-7.
8. Culmsee C, Junker V, Kremers W, Thal S, Plesnila N, Krieglstein J. Combination therapy in ischemic stroke: synergistic neuroprotective effects of memantine and clenbuterol. Stroke 2004; 35: 1197-202.
9. Deitmer JW, Rose CR. pH regulation and proton signalling by glial cells. Prog Neurobiol 1996; 48: 73-103.
10. 2+ concentration changes in cultured postnatal rat hippocampal neurons. Neuroscience 1999; 93: 1003-16.
11. Dirnagl U, Iadecola C, Moskowitz MA. Pathobiology of ischaemic stroke: an integrated view. Trends Neurosci 1999; 22: 391-7.
12. Duggan A, Garcia-Anoveros J, Corey DP. The PDZ domain protein PICK1 and the sodium channel BNaC1 interact and localize at mechanosensory terminals of dorsal root ganglion neurons and dendrites of central neurons. J Biol Chem 2002; 277: 5203-8.
13. + channels. J Biol Chem 2000; 275: 25116-21.
14. Gao J, Duan B, Wang DG, Deng XH, Zhang GY, Xu L, et al. Coupling between NMDA receptor and acid-sensing ion channel contributes to ischemic neuronal death. Neuron 2005; 48: 635-46.
15. Gladstone DJ, Black SE, Hakim AM. Toward wisdom from failure: lessons from neuroprotective stroke trials and new therapeutic directions. Stroke 2002; 33: 2123-36.
16. Illum L. Transport of drugs from the nasal cavity to the central nervous system. Eur J Pharm Sci 2000; 11: 1-18.
17. Kawano T, Anrather J, Zhou P, Park L, Wang G, Frys KA, et al. Prostaglandin E2 EP1 receptors: downstream effectors of COX-2 neurotoxicity. Nat Med 2006; 12: 225-9.
18. Krishtal O. The ASICs: signaling molecules? Modulators? Trends Neurosci 2003; 26: 477-83.
19. PA, Siesjo BK. Role of hyperglycaemia-related acidosis in ischaemic brain damage. Acta Physiol Scand 1997; 161: 567-80.
20. Lingueglia E, de Weille JR, Bassilana F, Heurteaux C, Sakai H, Waldmann R, et al. A modulatory subunit of acid sensing ion channels in brain and dorsal root ganglion cells. J Biol Chem 1997; 272: 29778-83.
21. Liu XF, Fawcett JR, Thorne RG, DeFor TA, Frey WH II. Intranasal administration of insulin-like growth factor-I bypasses the blood-brain barrier and protects against focal cerebral ischemic damage. J Neurol Sci 2001a; 187: 91-7.
22. Liu XF, Fawcett JR, Thorne RG, Frey WH II. Non-invasive intranasal insulin-like growth factor-I reduces infarct volume and improves neurologic function in rats following middle cerebral artery occlusion. Neurosci Lett 2001b; 308: 91-4.
23. Longa EZ, Weinstein PR, Carlson S, Cummins R. Reversible middle cerebral artery occlusion without craniectomy in rats. Stroke 1989; 20: 84-91.
24. Marler JR. For the NINDS Study Group. Tissue plasmimogem activator for acute ischaemic stroke. N Emgl J Med 1995; 24: 1581-7.
25. Obrenovitch TP, Scheller D, Matsumoto T, Tegtmeier F, Holler M, Symon L. A rapid redistribution of hydrogen ions is associated with depolarization and repolarization subsequent to cerebral ischemia reperfusion. J Neurophysiol 1990; 64: 1125-33.
26. Pignataro G, Gala R, Cuomo O, Tortiglione A, Giaccio L, Castaldo P, et al. Two sodium/calcium exchanger gene products, NCX1 and NCX3, play a major role in the development of permanent focal cerebral ischemia. Stroke 2004; 35: 2566-70.
27. Siesjo BK. Pathophysiology and treatment of focal cerebral ischemia. Part II: mechanisms of damage and treatment. J Neurosurg 1992; 77: 337-54.
28. Simpson EM, Linder CC, Sargent EE, Davisson MT, Mobraaten LE, Sharp JJ. Genetic variation among 129 substrains and its importance for targeted mutagenesis in mice. Nat Genet 1997; 16: 19-27.
29. Thorne RG, Frey WH II. Delivery of neurotrophic factors to the central nervous system: pharmacokinetic considerations. Clin Pharmacokinet 2001; 40: 907-46.
30. Wahlgren NG, Ahmed N. Neuroprotection in cerebral ischaemia: facts and fancies - the need for new approaches. Cerebrovasc Dis 2004; 17 (Suppl 1): 153-66.
31. Waldmann R, Champigny G, Voilley N, Lauritzen I, Lazdunski M. The mammalian degenerin MDEG, an amiloride-sensitive cation channel activated by mutations causing neurodegeneration in Caenorhabditis elegans. J Biol Chem 1996; 271: 10433-6.
32. Waldmann R, Bassilana F, de Weille J, Champigny G, Heurteaux C, Lazdunski M. Molecular cloning of a non-inactivating proton-gated Na+ channel specific for sensory neurons. J Biol Chem 1997a; 272: 20975-8.
33. Waldmann R, Champigny G, Bassilana F, Heurteaux C, Lazdunski M. A proton-gated cation channel involved in acid-sensing. Nature 1997b; 386: 173-7.
34. Wemmie JA, Chen J, Askwith CC, Hruska-Hageman AM, Price MP, Nolan BC, et al. The acid-activated ion channel ASIC contributes to synaptic plasticity, learning, and memory. Neuron 2002; 34: 463-77.
35. Wemmie JA, Askwith CC, Lamani E, Cassell MD, Freeman JH Jr, Welsh MJ. Acid-sensing ion channel 1 is localized in brain regions with high synaptic density and contributes to fear conditioning. J Neurosci 2003; 23: 5496-502.
36. Wemmie JA, Coryell MW, Askwith CC, Lamani E, Leonard AS, Sigmund CD, et al. Overexpression of acid-sensing ion channel 1a in transgenic mice increases acquired fear-related behavior. Proc Natl Acad Sci USA 2004; 101: 3621-6.
37. Wu LJ, Duan B, Mei YD, Gao J, Chen JG, Zhuo M, et al. Characterization of acid-sensing ion channels in dorsal horn neurons of rat spinal cord. J Biol Chem 2004; 279: 43716-24.
38. Xiong ZG, Zhu XM, Chu XP, Minami M, Hey J, Wei WL, et al. Neuroprotection in ischemia: blocking calcium-permeable acid-sensing ion channels. Cell 2004; 118: 687-98.
39. Yermolaieva O, Leonard AS, Schnizler MK, Abboud FM, Welsh MJ. Extracellular acidosis increases neuronal cell calcium by activating acid-sensing ion channel 1a. Proc Natl Acad Sci USA 2004; 101: 6752-7.