CNS-derived interleukin-4 is essential for the regulation of autoimmune inflammation and induces a state of alternative activation in microglial cells

Journal of Neuroscience

Volumn 27, Issue 40, 2007, Pages 10714-10721

  Ponomarev, Eugene D ^a   Maresz, Katarzyna ^a   Tan, Yanping ^a   Dittel, Bonnie N ^a,b  

^a BLOOD RESEARCH INSTITUTE   (United States)

^b NONE   (United States)

Author keywords

Activation; Autoimmunity; Encephalomyelitis; Interleukin; Macrophage; Microglia; Multiple sclerosis; Neuroinflammation

Indexed keywords

INTERLEUKIN 4; NITRIC OXIDE;

ALLERGIC ENCEPHALOMYELITIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; AUTOIMMUNITY; CELL ACTIVATION; CENTRAL NERVOUS SYSTEM; CONTROLLED STUDY; CYTOKINE PRODUCTION; INFLAMMATION; INFLAMMATORY CELL; MACROPHAGE ACTIVATION; MICROGLIA; MOUSE; MULTIPLE SCLEROSIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION;

ANIMALS; BETA-N-ACETYLHEXOSAMINIDASES; CELLS, CULTURED; CENTRAL NERVOUS SYSTEM; ENCEPHALOMYELITIS, AUTOIMMUNE, EXPERIMENTAL; FLOW CYTOMETRY; GENE EXPRESSION REGULATION; INTERLEUKIN-4; LECTINS; MACROPHAGES; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; MICE, KNOCKOUT; MICROGLIA; NERVE GROWTH FACTOR; NITRIC OXIDE; PROTEINS; RECEPTORS, CELL SURFACE; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER;

EID: 35148835215     PISSN: 02706474     EISSN: 02706474     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.1922-07.2007     Document Type: Article

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