메뉴 건너뛰기




Volumn 160, Issue 2, 1999, Pages 361-375

Dynorphin A (1-13) neurotoxicity in vitro: Opioid and non-opioid mechanisms in mouse spinal cord neurons

Author keywords

2 amino 5 phosphopentanoic acid; 7 chlorokynurenic acid; Intracellular calcium; MK 801 (Dizocilpine); Neuroprotection; Neurotoxicology; Nor binaltorphimine; opioid receptors, N methyl D aspartate receptors

Indexed keywords

2 AMINO 5 PHOSPHONOVALERIC ACID; 7 CHLOROKYNURENIC ACID; DIZOCILPINE; DYNORPHIN[1-13]; EXCITOTOXIN; KAPPA OPIATE RECEPTOR; KAPPA OPIATE RECEPTOR ANTAGONIST; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; N METHYL DEXTRO ASPARTIC ACID RECEPTOR BLOCKING AGENT; NALOXONE; NORBINALTORPHIMINE; OPIATE ANTAGONIST; OPIATE PEPTIDE;

EID: 0032786125     PISSN: 00144886     EISSN: None     Source Type: Journal    
DOI: 10.1006/exnr.1999.7235     Document Type: Article
Times cited : (53)

References (95)
  • 3
    • 0028303596 scopus 로고
    • Prodynorphin gene expression relates to NF-kappaB factors
    • Bakalkin G., Yakovleva T., Terenius L. Prodynorphin gene expression relates to NF-kappaB factors. Mol. Brain Res. 24:1994;301-312.
    • (1994) Mol. Brain Res. , vol.24 , pp. 301-312
    • Bakalkin, G.1    Yakovleva, T.2    Terenius, L.3
  • 4
    • 0025654821 scopus 로고
    • Dynorphin A-(1-17) induces alterations in free fatty acids, excitatory amino acids, and motor function through an opiate- receptor-mediated mechanism
    • Bakshi R., Newman A. H., Faden A. I. Dynorphin A-(1-17) induces alterations in free fatty acids, excitatory amino acids, and motor function through an opiate- receptor-mediated mechanism. J. Neurosci. 10:1990;3793-3800.
    • (1990) J. Neurosci. , vol.10 , pp. 3793-3800
    • Bakshi, R.1    Newman, A.H.2    Faden, A.I.3
  • 5
    • 0026659498 scopus 로고
    • N-Methyl-d-aspartate (NMDA) and opioid receptors mediate dynorphin-induced spinal cord injury: Behavioral and histological studies
    • Bakshi R., Ni R.-X., Faden A. I. N-Methyl-d-aspartate (NMDA) and opioid receptors mediate dynorphin-induced spinal cord injury: Behavioral and histological studies. Brain Res. 580:1992;255-264.
    • (1992) Brain Res. , vol.580 , pp. 255-264
    • Bakshi, R.1    Ni, R.-X.2    Faden, A.I.3
  • 6
    • 0027226219 scopus 로고
    • Optimized survival of hippocampal neurons in B27-supplemented Neurobasal, a new serum-free medium combination
    • Brewer G. J., Torricelli J. R., Evege E. K., Price P. J. Optimized survival of hippocampal neurons in B27-supplemented Neurobasal, a new serum-free medium combination. J. Neurosci. Res. 35:1993;567-576.
    • (1993) J. Neurosci. Res. , vol.35 , pp. 567-576
    • Brewer, G.J.1    Torricelli, J.R.2    Evege, E.K.3    Price, P.J.4
  • 7
    • 0031971454 scopus 로고    scopus 로고
    • Ifenprodil blocks the excitatory effects of the opioid peptide dynorphin 1-17 on NMDA receptor-mediated currents in the CA3 region of the guinea pig hippocampus
    • Caudle R. M., Dubner R. Ifenprodil blocks the excitatory effects of the opioid peptide dynorphin 1-17 on NMDA receptor-mediated currents in the CA3 region of the guinea pig hippocampus. Neuropeptides. 32:1998;87-95.
    • (1998) Neuropeptides , vol.32 , pp. 87-95
    • Caudle, R.M.1    Dubner, R.2
  • 8
    • 0020029345 scopus 로고
    • Dynorphin is a specific endogenous ligand of the kappa opioid receptor
    • Chavkin C., James I. F., Goldstein A. Dynorphin is a specific endogenous ligand of the kappa opioid receptor. Science. 215:1982;413-415.
    • (1982) Science , vol.215 , pp. 413-415
    • Chavkin, C.1    James, I.F.2    Goldstein, A.3
  • 9
    • 0029005428 scopus 로고
    • The mechanism of action for the block of NMDA receptor channels by the opioid peptide dynorphin
    • Chen L., Gu Y., Huang L.-Y. M. The mechanism of action for the block of NMDA receptor channels by the opioid peptide dynorphin. J. Neurosci. 15:1995;4602-4611.
    • (1995) J. Neurosci. , vol.15 , pp. 4602-4611
    • Chen, L.1    Gu, Y.2    Huang, L.-Y.M.3
  • 10
    • 0028949109 scopus 로고
    • The opioid peptide dynorphin directly blocks NMDA receptor channels in the rat
    • Chen L., Gu Y., Huang L.-Y. M. The opioid peptide dynorphin directly blocks NMDA receptor channels in the rat. J. Physiol. (London). 482:1995;575-581.
    • (1995) J. Physiol. (London) , vol.482 , pp. 575-581
    • Chen, L.1    Gu, Y.2    Huang, L.-Y.M.3
  • 11
    • 0026552808 scopus 로고
    • 2+ block of NMDA-receptor channels as a mechanism of modulation
    • 2+ block of NMDA-receptor channels as a mechanism of modulation. Nature. 356:1992;521-523.
    • (1992) Nature , vol.356 , pp. 521-523
    • Chen, L.1    Huang, L.-Y.M.2
  • 12
    • 0026497926 scopus 로고
    • Excitotoxic cell death
    • Choi D. W. Excitotoxic cell death. J. Neurobiol. 23:1992;1261-1276.
    • (1992) J. Neurobiol. , vol.23 , pp. 1261-1276
    • Choi, D.W.1
  • 16
    • 0025060239 scopus 로고
    • Opioids can evoke direct receptor-mediated excitatory effects on sensory neurons
    • Crain S. M., Shen K. F. Opioids can evoke direct receptor-mediated excitatory effects on sensory neurons. Trends Pharmacol. Sci. 11:1990;77-81.
    • (1990) Trends Pharmacol. Sci. , vol.11 , pp. 77-81
    • Crain, S.M.1    Shen, K.F.2
  • 17
    • 0030983782 scopus 로고    scopus 로고
    • Chronic exposure to kappa-opioids enhances the susceptibility of immortalized neurons (F-11kappa 7) to apoptosis-inducing drugs by a mechanism that may involve ceramide
    • Dawson G., Dawson S. A., Goswami R. Chronic exposure to kappa-opioids enhances the susceptibility of immortalized neurons (F-11kappa 7) to apoptosis-inducing drugs by a mechanism that may involve ceramide. J. Neurochem. 68:1997;2363-2370.
    • (1997) J. Neurochem. , vol.68 , pp. 2363-2370
    • Dawson, G.1    Dawson, S.A.2    Goswami, R.3
  • 18
    • 0026500432 scopus 로고
    • Activity-dependent neuronal plasticity following tissue injury and inflammation
    • Dubner R., Ruda M. A. Activity-dependent neuronal plasticity following tissue injury and inflammation. Trends Neurosci. 15:1992;96-103.
    • (1992) Trends Neurosci. , vol.15 , pp. 96-103
    • Dubner, R.1    Ruda, M.A.2
  • 20
    • 0026601969 scopus 로고
    • Dynorphin increases extracellular levels of excitatory amino acids in the brain through a non-opioid mechanism
    • Faden A. I. Dynorphin increases extracellular levels of excitatory amino acids in the brain through a non-opioid mechanism. J. Neurosci. 12:1992;425-429.
    • (1992) J. Neurosci. , vol.12 , pp. 425-429
    • Faden, A.I.1
  • 21
    • 0027884838 scopus 로고
    • Experimental neurobiology of central nervous system trauma
    • Faden A. I. Experimental neurobiology of central nervous system trauma. Crit. Rev. Neurobiol. 7:1993;175-186.
    • (1993) Crit. Rev. Neurobiol. , vol.7 , pp. 175-186
    • Faden, A.I.1
  • 22
    • 0021803767 scopus 로고
    • Endogenous opioid immunoreactivity in rat spinal cord following traumatic injury
    • Faden A. I., Molineaux C. J., Rosenberger J. G., Jacobs T. P., Cox B. M. Endogenous opioid immunoreactivity in rat spinal cord following traumatic injury. Ann. Neurol. 17:1985;386-390.
    • (1985) Ann. Neurol. , vol.17 , pp. 386-390
    • Faden, A.I.1    Molineaux, C.J.2    Rosenberger, J.G.3    Jacobs, T.P.4    Cox, B.M.5
  • 23
    • 0026540898 scopus 로고
    • Pharmacological strategies in CNS trauma
    • Faden A. I., Salzman S. Pharmacological strategies in CNS trauma. Trends Pharmacol. Sci. 13:1992;29-35.
    • (1992) Trends Pharmacol. Sci. , vol.13 , pp. 29-35
    • Faden, A.I.1    Salzman, S.2
  • 24
    • 0025859293 scopus 로고
    • U-50, 488H inhibits dynorphin and glutamate release from guinea pig hippocampal mossy fiber terminals
    • Gannon R. L., Terrian D. M. U-50, 488H inhibits dynorphin and glutamate release from guinea pig hippocampal mossy fiber terminals. Brain Res. 548:1991;242-247.
    • (1991) Brain Res. , vol.548 , pp. 242-247
    • Gannon, R.L.1    Terrian, D.M.2
  • 25
    • 0026763483 scopus 로고
    • Kappa opioid agonists inhibit transmitter release from guinea pig hippocampal mossy fiber synaptosomes
    • Gannon R. L., Terrian D. M. Kappa opioid agonists inhibit transmitter release from guinea pig hippocampal mossy fiber synaptosomes. Neurochem. Res. 17:1992;741-747.
    • (1992) Neurochem. Res. , vol.17 , pp. 741-747
    • Gannon, R.L.1    Terrian, D.M.2
  • 26
    • 0028350983 scopus 로고
    • Evaluation of neuroprotection and behavioral recovery by the kappa-opioid, PD117302, following transient forebrain ischemia
    • Genovese R. F., Moreton J. E., Tortella F. C. Evaluation of neuroprotection and behavioral recovery by the kappa-opioid, PD117302, following transient forebrain ischemia. Brain Res. Bull. 34:1994;111-116.
    • (1994) Brain Res. Bull. , vol.34 , pp. 111-116
    • Genovese, R.F.1    Moreton, J.E.2    Tortella, F.C.3
  • 27
    • 0027164322 scopus 로고
    • Antagonists of excitatory amino acids and endogenous opioid peptides in the treatment of experimental central nervous system injury
    • Gentile N. T., McIntosh T. K. Antagonists of excitatory amino acids and endogenous opioid peptides in the treatment of experimental central nervous system injury. Ann. Emerg. Med. 22:1993;1028-1034.
    • (1993) Ann. Emerg. Med. , vol.22 , pp. 1028-1034
    • Gentile, N.T.1    McIntosh, T.K.2
  • 28
    • 0023472337 scopus 로고
    • Binding selectivity profiles for ligands of multiple receptor types: Focus on opioid receptors
    • Goldstein A. Binding selectivity profiles for ligands of multiple receptor types: Focus on opioid receptors. Trends Pharmacol. Sci. 8:1987;456-459.
    • (1987) Trends Pharmacol. Sci. , vol.8 , pp. 456-459
    • Goldstein, A.1
  • 30
    • 0031882017 scopus 로고    scopus 로고
    • Cyclic AMP protects against staurosporine and wortmannin-induced apoptosis and opioid-enhanced apoptosis in both embryonic and immortalized (F-11kappa7) neurons
    • Goswami R., Dawson S. A., Dawson G. Cyclic AMP protects against staurosporine and wortmannin-induced apoptosis and opioid-enhanced apoptosis in both embryonic and immortalized (F-11kappa7) neurons. J. Neurochem. 70:1998;1376-1382.
    • (1998) J. Neurochem. , vol.70 , pp. 1376-1382
    • Goswami, R.1    Dawson, S.A.2    Dawson, G.3
  • 32
    • 0021895138 scopus 로고
    • A new generation of calcium indicators with greatly improved fluorescence properties
    • Grynkiewicz G., Poenie M., Tsien R. Y. A new generation of calcium indicators with greatly improved fluorescence properties. J. Biol. Chem. 260:1985;3440-3450.
    • (1985) J. Biol. Chem. , vol.260 , pp. 3440-3450
    • Grynkiewicz, G.1    Poenie, M.2    Tsien, R.Y.3
  • 33
    • 0028592633 scopus 로고
    • Morphine inhibits Purkinje cell survival and dendritic differentiation in organotypic cultures of the mouse cerebellum
    • Hauser K. F., Gurwell J. A., Turbek C. S. Morphine inhibits Purkinje cell survival and dendritic differentiation in organotypic cultures of the mouse cerebellum. Exp. Neurol. 130:1994;95-105.
    • (1994) Exp. Neurol. , vol.130 , pp. 95-105
    • Hauser, K.F.1    Gurwell, J.A.2    Turbek, C.S.3
  • 34
    • 0032421651 scopus 로고    scopus 로고
    • Diversity of the endogenous opioid system in development: Novel signal transduction translates multiple extracellular signals into neural cell growth and differentiation
    • Hauser K. F., Mangoura D. Diversity of the endogenous opioid system in development: Novel signal transduction translates multiple extracellular signals into neural cell growth and differentiation. Perspect. Dev. Neurobiol. 5:1998;437-449.
    • (1998) Perspect. Dev. Neurobiol. , vol.5 , pp. 437-449
    • Hauser, K.F.1    Mangoura, D.2
  • 35
    • 0024550983 scopus 로고
    • Androgen increases the number of cells in fetal mouse spinal cord cultures: Implications for motoneuron survival
    • Hauser K. F., Toran-Allerand C. D. Androgen increases the number of cells in fetal mouse spinal cord cultures: Implications for motoneuron survival. Brain Res. 485:1989;157-164.
    • (1989) Brain Res. , vol.485 , pp. 157-164
    • Hauser, K.F.1    Toran-Allerand, C.D.2
  • 36
    • 0021952580 scopus 로고
    • Antinociception and paralysis induced by intrathecal dynorphin A
    • Herman B. H., Goldstein A. Antinociception and paralysis induced by intrathecal dynorphin A. J. Pharmacol. Exp. Ther. 232:1985;27-32.
    • (1985) J. Pharmacol. Exp. Ther. , vol.232 , pp. 27-32
    • Herman, B.H.1    Goldstein, A.2
  • 37
    • 0000757603 scopus 로고
    • Cellular mechanisms of excitatory and inhibitory actions of opioids
    • L. F. Tseng. Reading: Harwood Academic
    • Huang L.-Y. M. Cellular mechanisms of excitatory and inhibitory actions of opioids. Tseng L. F. The Pharmacology of Opioid Peptides. 1995;131-149 Harwood Academic, Reading.
    • (1995) The Pharmacology of Opioid Peptides , pp. 131-149
    • Huang, L.-Y.M.1
  • 38
    • 0025955168 scopus 로고
    • The kappa opioid-related anticonvulsants U-50488H and U-54494A attenuate N-methyl-d-aspartate induced brain injury in the neonatal rat
    • Hudson C. J., Von Voigtlander P. F., Althaus J. S., Scherch H. M., Means E. D. The kappa opioid-related anticonvulsants U-50488H and U-54494A attenuate N-methyl-d-aspartate induced brain injury in the neonatal rat. Brain Res. 564:1991;261-267.
    • (1991) Brain Res. , vol.564 , pp. 261-267
    • Hudson, C.J.1    Von Voigtlander, P.F.2    Althaus, J.S.3    Scherch, H.M.4    Means, E.D.5
  • 39
    • 0025130604 scopus 로고
    • Dynorphin A: In vivo release in the spinal cord of the cat
    • Hutchison W. D., Morton C. R., Terenius L. Dynorphin A: In vivo release in the spinal cord of the cat. Brain Res. 532:1990;299-306.
    • (1990) Brain Res. , vol.532 , pp. 299-306
    • Hutchison, W.D.1    Morton, C.R.2    Terenius, L.3
  • 40
    • 0025106954 scopus 로고
    • MK-801 blocks dynorphin A (1-13)-induced loss of the tail-flick reflex in the rat
    • Isaac L., O'Malley T. V. Z., Ristic H., Stewart P. MK-801 blocks dynorphin A (1-13)-induced loss of the tail-flick reflex in the rat. Brain Res. 531:1990;83-87.
    • (1990) Brain Res. , vol.531 , pp. 83-87
    • Isaac, L.1    O'Malley, T.V.Z.2    Ristic, H.3    Stewart, P.4
  • 42
    • 0023091647 scopus 로고
    • Glycine potentiates the NMDA response in cultured mouse brain neurones
    • Johnson J. W., Ascher P. Glycine potentiates the NMDA response in cultured mouse brain neurones. Nature. 325:1987;529-531.
    • (1987) Nature , vol.325 , pp. 529-531
    • Johnson, J.W.1    Ascher, P.2
  • 43
    • 0028861259 scopus 로고
    • The opioid peptide dynorphin modulates AMPA and kainate responses in acutely isolated neurons from the dorsal horn
    • Kolaj M., Cerne R., Randic M. The opioid peptide dynorphin modulates AMPA and kainate responses in acutely isolated neurons from the dorsal horn. Brain Res. 671:1995;227-244.
    • (1995) Brain Res. , vol.671 , pp. 227-244
    • Kolaj, M.1    Cerne, R.2    Randic, M.3
  • 44
    • 0032524331 scopus 로고    scopus 로고
    • Dynorphin uses a non-opioid mechanism to potentiate N-methyl-d-aspartate currents in single rat periaqueductal gray neurons
    • Lai S. L., Gu Y., Huang L. Y. Dynorphin uses a non-opioid mechanism to potentiate N-methyl-d-aspartate currents in single rat periaqueductal gray neurons. Neurosci. Lett. 247:1998;115-118.
    • (1998) Neurosci. Lett. , vol.247 , pp. 115-118
    • Lai, S.L.1    Gu, Y.2    Huang, L.Y.3
  • 45
    • 0030879183 scopus 로고    scopus 로고
    • Spinally administered dynorphin A produces long-lasting allodynia: Involvement of NMDA but not opioid receptors
    • Laughlin T. M., Vanderah T. W., Lashbrook J., Nichols M. L., Ossipov M., Porreca F., Wilcox G. L. Spinally administered dynorphin A produces long-lasting allodynia: Involvement of NMDA but not opioid receptors. Pain. 72:1997;253-260.
    • (1997) Pain , vol.72 , pp. 253-260
    • Laughlin, T.M.1    Vanderah, T.W.2    Lashbrook, J.3    Nichols, M.L.4    Ossipov, M.5    Porreca, F.6    Wilcox, G.L.7
  • 46
    • 0022841319 scopus 로고
    • Intrathecal dynorphin A (1-13) and (3-13) reduce spinal cord blood flow by non-opioid mechanisms
    • Long J. B., Kinney R. C., Malcolm D. S., Graeber G. M., Holaday J. W. Intrathecal dynorphin A (1-13) and (3-13) reduce spinal cord blood flow by non-opioid mechanisms. NIDA Res. Monogr. 75:1986;524-526.
    • (1986) NIDA Res. Monogr. , vol.75 , pp. 524-526
    • Long, J.B.1    Kinney, R.C.2    Malcolm, D.S.3    Graeber, G.M.4    Holaday, J.W.5
  • 47
    • 0023522076 scopus 로고
    • Intrathecal dynorphin A1-13 and dynorphin A3-13 reduce rat spinal cord blood flow by non-opioid mechanisms
    • Long J. B., Kinney R. C., Malcolm D. S., Graeber G. M., Holaday J. W. Intrathecal dynorphin A1-13 and dynorphin A3-13 reduce rat spinal cord blood flow by non-opioid mechanisms. Brain Res. 436:1987;374-379.
    • (1987) Brain Res. , vol.436 , pp. 374-379
    • Long, J.B.1    Kinney, R.C.2    Malcolm, D.S.3    Graeber, G.M.4    Holaday, J.W.5
  • 48
    • 0023735298 scopus 로고
    • Hindlimb paralytic effects of prodynorphin-derived peptides following spinal subarachnoid injection in rats
    • Long J. B., Martinez-Arizala A., Echevarria E. E., Tidwell R. E., Holaday J. W. Hindlimb paralytic effects of prodynorphin-derived peptides following spinal subarachnoid injection in rats. Eur. J. Pharmacol. 153:1988;45-54.
    • (1988) Eur. J. Pharmacol. , vol.153 , pp. 45-54
    • Long, J.B.1    Martinez-Arizala, A.2    Echevarria, E.E.3    Tidwell, R.E.4    Holaday, J.W.5
  • 50
    • 0028344182 scopus 로고
    • Dynorphin A-induced rat spinal cord injury: Evidence for excitatory amino acid involvement in a pharmacological model of ischemic spinal cord injury
    • Long J. B., Rigamonti D. D., Oleshansky M. A., Wingfield C. P., Martinez-Arizala A. Dynorphin A-induced rat spinal cord injury: Evidence for excitatory amino acid involvement in a pharmacological model of ischemic spinal cord injury. J. Pharmacol. Exp. Ther. 269:1994;358-366.
    • (1994) J. Pharmacol. Exp. Ther. , vol.269 , pp. 358-366
    • Long, J.B.1    Rigamonti, D.D.2    Oleshansky, M.A.3    Wingfield, C.P.4    Martinez-Arizala, A.5
  • 51
    • 0022558585 scopus 로고
    • Dynorphin A decreases voltage-dependent calcium conductance of mouse dorsal root ganglion neurones
    • Macdonald R. L., Werz M. A. Dynorphin A decreases voltage-dependent calcium conductance of mouse dorsal root ganglion neurones. J. Physiol. (London). 377:1986;237-249.
    • (1986) J. Physiol. (London) , vol.377 , pp. 237-249
    • Macdonald, R.L.1    Werz, M.A.2
  • 52
    • 0029175202 scopus 로고
    • Calcium, free radicals, and excitotoxic neuronal death in primary cell culture
    • Mattson M. P., Barger S. W., Begley J. G., Mark R. J. Calcium, free radicals, and excitotoxic neuronal death in primary cell culture. Methods Cell Biol. 46:1995;187-216.
    • (1995) Methods Cell Biol. , vol.46 , pp. 187-216
    • Mattson, M.P.1    Barger, S.W.2    Begley, J.G.3    Mark, R.J.4
  • 53
    • 0027247422 scopus 로고
    • Altered calcium signaling and neuronal injury: Stroke and Alzheimer's disease as examples
    • Mattson M. P., Rydel R. E., Lieberburg I., Smith-Swintosky V. L. Altered calcium signaling and neuronal injury: Stroke and Alzheimer's disease as examples. Ann. N.Y. Acad. Sci. 679:1993;1-21.
    • (1993) Ann. N.Y. Acad. Sci. , vol.679 , pp. 1-21
    • Mattson, M.P.1    Rydel, R.E.2    Lieberburg, I.3    Smith-Swintosky, V.L.4
  • 54
    • 0028218770 scopus 로고
    • Endogenous neuroprotection factors and traumatic brain injury: Mechanisms of action and implications for therapy
    • Mattson M. P., Scheff S. W. Endogenous neuroprotection factors and traumatic brain injury: Mechanisms of action and implications for therapy. J. Neurotrauma. 11:1994;3-33.
    • (1994) J. Neurotrauma , vol.11 , pp. 3-33
    • Mattson, M.P.1    Scheff, S.W.2
  • 55
    • 0027717489 scopus 로고
    • Beneficial effect of the nonselective opiate antagonist naloxone hydrochloride and the thyrotropin-releasing hormone (TRH) analog YM-14673 on long-term neurobehavioral outcome following experimental brain injury in the rat
    • McIntosh T. K., Fernyak S., Hayes R. L., Faden A. I. Beneficial effect of the nonselective opiate antagonist naloxone hydrochloride and the thyrotropin-releasing hormone (TRH) analog YM-14673 on long-term neurobehavioral outcome following experimental brain injury in the rat. J. Neurotrauma. 10:1993;373-384.
    • (1993) J. Neurotrauma , vol.10 , pp. 373-384
    • McIntosh, T.K.1    Fernyak, S.2    Hayes, R.L.3    Faden, A.I.4
  • 56
    • 0028041046 scopus 로고
    • Central and systemic kappa-opioid agonists exacerbate neurobehavioral response to brain injury in rats
    • McIntosh T. K., Fernyak S., Yamakami I., Faden A. I. Central and systemic kappa-opioid agonists exacerbate neurobehavioral response to brain injury in rats. Am. J. Physiol. 267:1994;R665-R672.
    • (1994) Am. J. Physiol. , vol.267
    • McIntosh, T.K.1    Fernyak, S.2    Yamakami, I.3    Faden, A.I.4
  • 57
    • 0023473202 scopus 로고
    • Endogenous opioids may mediate secondary damage after experimental brain injury
    • McIntosh T. K., Hayes R. L., DeWitt D. S., Agura V., Faden A. I. Endogenous opioids may mediate secondary damage after experimental brain injury. Am. J. Physiol. 253:1987;E565-E574.
    • (1987) Am. J. Physiol. , vol.253
    • McIntosh, T.K.1    Hayes, R.L.2    Dewitt, D.S.3    Agura, V.4    Faden, A.I.5
  • 58
    • 0023553426 scopus 로고
    • Alterations in regional concentrations of endogenous opioids following traumatic brain injury in the cat
    • McIntosh T. K., Head V. A., Faden A. I. Alterations in regional concentrations of endogenous opioids following traumatic brain injury in the cat. Brain Res. 425:1987;225-233.
    • (1987) Brain Res. , vol.425 , pp. 225-233
    • McIntosh, T.K.1    Head, V.A.2    Faden, A.I.3
  • 59
    • 0026340654 scopus 로고
    • Endogenous opioids modulate neuronal survival in the developing avian ciliary ganglion
    • Meriney S. D., Ford M. J., Oliva D., Pilar G. Endogenous opioids modulate neuronal survival in the developing avian ciliary ganglion. J. Neurosci. 11:1991;3705-3717.
    • (1991) J. Neurosci. , vol.11 , pp. 3705-3717
    • Meriney, S.D.1    Ford, M.J.2    Oliva, D.3    Pilar, G.4
  • 60
    • 0021802754 scopus 로고
    • Morphine-induced delay of normal cell death in the avian ciliary ganglion
    • Meriney S. D., Gray D. B., Pilar G. Morphine-induced delay of normal cell death in the avian ciliary ganglion. Science. 228:1985;1451-1453.
    • (1985) Science , vol.228 , pp. 1451-1453
    • Meriney, S.D.1    Gray, D.B.2    Pilar, G.3
  • 61
    • 0028158180 scopus 로고
    • Voltage-dependent effects of opioid peptides on hippocampal CA3 pyramidal neurons in vitro
    • Moore S. D., Madamba S. G., Schweitzer P., Siggins G. R. Voltage-dependent effects of opioid peptides on hippocampal CA3 pyramidal neurons in vitro. J. Neurosci. 14:1994;809-820.
    • (1994) J. Neurosci. , vol.14 , pp. 809-820
    • Moore, S.D.1    Madamba, S.G.2    Schweitzer, P.3    Siggins, G.R.4
  • 62
    • 0006058994 scopus 로고
    • Ischemic rat spinal cord injury induced by dynorphin A involves elevations in extracellular excitatory amino acids
    • Oleshansky M. A., Long J. B. Ischemic rat spinal cord injury induced by dynorphin A involves elevations in extracellular excitatory amino acids. Soc. Neurosci. Abstr. 17:1991;1268.
    • (1991) Soc. Neurosci. Abstr. , vol.17 , pp. 1268
    • Oleshansky, M.A.1    Long, J.B.2
  • 63
    • 0026074121 scopus 로고
    • The effects of dynorphin A (1-13) and U50, 488H on free intracellular calcium in guinea pig cerebellar synaptosomes
    • Olson K. G., Welch S. P. The effects of dynorphin A (1-13) and U50, 488H on free intracellular calcium in guinea pig cerebellar synaptosomes. Life Sci. 48:1991;575-581.
    • (1991) Life Sci. , vol.48 , pp. 575-581
    • Olson, K.G.1    Welch, S.P.2
  • 64
    • 0032584964 scopus 로고    scopus 로고
    • Opposing actions of the EGF family and opioids: Heparin binding-epidermal growth factor (HB-EGF) protects mouse cerebellar neuroblasts against the antiproliferative effect of morphine
    • Opanashuk L. A., Hauser K. F. Opposing actions of the EGF family and opioids: Heparin binding-epidermal growth factor (HB-EGF) protects mouse cerebellar neuroblasts against the antiproliferative effect of morphine. Brain Res. 804:1998;87-94.
    • (1998) Brain Res. , vol.804 , pp. 87-94
    • Opanashuk, L.A.1    Hauser, K.F.2
  • 65
    • 0030220893 scopus 로고    scopus 로고
    • Neurotrophic survival molecules for motoneurons: An embarrassment of riches
    • Oppenheim R. W. Neurotrophic survival molecules for motoneurons: An embarrassment of riches. Neuron. 17:1996;195-197.
    • (1996) Neuron , vol.17 , pp. 195-197
    • Oppenheim, R.W.1
  • 66
    • 0025811297 scopus 로고
    • Control of embryonic motoneuron survival in vivo by ciliary neurotrophic factor
    • Oppenheim R. W., Prevette D., Yin Q. W., Collins F., MacDonald J. Control of embryonic motoneuron survival in vivo by ciliary neurotrophic factor. Science. 251:1991;1616-1618.
    • (1991) Science , vol.251 , pp. 1616-1618
    • Oppenheim, R.W.1    Prevette, D.2    Yin, Q.W.3    Collins, F.4    MacDonald, J.5
  • 68
    • 0028157362 scopus 로고
    • Light and electron microscope distribution of the NMDA receptor subunit NMDAR1 in the rat nervous system using a selective anti-peptide antibody
    • Petralia R. S., Yokotani N., Wenthold R. J. Light and electron microscope distribution of the NMDA receptor subunit NMDAR1 in the rat nervous system using a selective anti-peptide antibody. J. Neurosci. 14:1994;667-696.
    • (1994) J. Neurosci. , vol.14 , pp. 667-696
    • Petralia, R.S.1    Yokotani, N.2    Wenthold, R.J.3
  • 69
    • 0031017076 scopus 로고    scopus 로고
    • Enkephalinergic and dynorphinergic neurons in the spinal cord and dorsal root ganglia of the polyarthritic rat - In vivo release and cDNA hybridization studies
    • Pohl M., Ballet S., Collin E., Mauborgne A., Bourgoin S., Benoliel J. J., Hamon M., Cesselin F. Enkephalinergic and dynorphinergic neurons in the spinal cord and dorsal root ganglia of the polyarthritic rat - In vivo release and cDNA hybridization studies. Brain Res. 749:1997;18-28.
    • (1997) Brain Res. , vol.749 , pp. 18-28
    • Pohl, M.1    Ballet, S.2    Collin, E.3    Mauborgne, A.4    Bourgoin, S.5    Benoliel, J.J.6    Hamon, M.7    Cesselin, F.8
  • 70
    • 0032483540 scopus 로고    scopus 로고
    • Mu-Opioid receptor activates signaling pathways implicated in cell survival and translational control
    • Polakiewicz R. D., Schieferl S. M., Gingras A. C., Sonenberg N., Comb M. J. mu-Opioid receptor activates signaling pathways implicated in cell survival and translational control. J. Biol. Chem. 273:1998;23534-23541.
    • (1998) J. Biol. Chem. , vol.273 , pp. 23534-23541
    • Polakiewicz, R.D.1    Schieferl, S.M.2    Gingras, A.C.3    Sonenberg, N.4    Comb, M.J.5
  • 72
    • 0027496450 scopus 로고
    • Survival of extraocular muscle in long-term organotypic culture: Differential influence of appropriate and inappropriate motoneurons
    • Porter J. D., Hauser K. F. Survival of extraocular muscle in long-term organotypic culture: Differential influence of appropriate and inappropriate motoneurons. Dev. Biol. 160:1993;39-50.
    • (1993) Dev. Biol. , vol.160 , pp. 39-50
    • Porter, J.D.1    Hauser, K.F.2
  • 73
    • 0028670911 scopus 로고
    • Kappa opioid receptor agonists inhibit the pilocarpine-induced seizures and toxicity in the mouse
    • Przewlocka B., Machelska H., Lason W. Kappa opioid receptor agonists inhibit the pilocarpine-induced seizures and toxicity in the mouse. Eur. Neuropsychopharmacol. 4:1994;527-533.
    • (1994) Eur. Neuropsychopharmacol. , vol.4 , pp. 527-533
    • Przewlocka, B.1    Machelska, H.2    Lason, W.3
  • 74
    • 0029972784 scopus 로고    scopus 로고
    • Spinal release of immunoreactive dynorphin A (1-8) with the development of peripheral inflammation in the rat
    • Riley R. C., Zhao Z. Q., Duggan A. W. Spinal release of immunoreactive dynorphin A (1-8) with the development of peripheral inflammation in the rat. Brain Res. 710:1996;131-142.
    • (1996) Brain Res. , vol.710 , pp. 131-142
    • Riley, R.C.1    Zhao, Z.Q.2    Duggan, A.W.3
  • 75
    • 0026597543 scopus 로고
    • The polyamine spermine has multiple actions on N-methyl-d-aspartate receptor single channel currents in cultured cortical neurons
    • Rock D. M., Macdonald R. I. The polyamine spermine has multiple actions on N-methyl-d-aspartate receptor single channel currents in cultured cortical neurons. Mol. Pharmacol. 41:1991;83-88.
    • (1991) Mol. Pharmacol. , vol.41 , pp. 83-88
    • Rock, D.M.1    Macdonald, R.I.2
  • 76
    • 0022620257 scopus 로고
    • Glutamate and the pathophysiology of hypoxic-ischemic brain damage
    • Rothman S. M., Olney J. W. Glutamate and the pathophysiology of hypoxic-ischemic brain damage. Ann. Neurol. 19:1986;105-111.
    • (1986) Ann. Neurol. , vol.19 , pp. 105-111
    • Rothman, S.M.1    Olney, J.W.2
  • 78
    • 0026986667 scopus 로고
    • Central non-opioid physiological and pathophysiological effects of dynorphin A and related peptides
    • Shukla V. K., Lemaire S. Central non-opioid physiological and pathophysiological effects of dynorphin A and related peptides. J. Psychiatry Neurosci. 17:1992;106-119.
    • (1992) J. Psychiatry Neurosci. , vol.17 , pp. 106-119
    • Shukla, V.K.1    Lemaire, S.2
  • 79
    • 0028080298 scopus 로고
    • Non-opioid effects of dynorphins: Possible role of the NMDA receptor
    • Shukla V. K., Lemaire S. Non-opioid effects of dynorphins: Possible role of the NMDA receptor. Trends Pharmacol. Sci. 15:1994;420-424.
    • (1994) Trends Pharmacol. Sci. , vol.15 , pp. 420-424
    • Shukla, V.K.1    Lemaire, S.2
  • 80
    • 0026605218 scopus 로고
    • Selective potentiation of NMDA-induced activity and release of excitatory amino acids by dynorphin: Possible roles in paralysis and neurotoxicity
    • Skilling S. R., Sun X., Kurtz H. J., Larson A. A. Selective potentiation of NMDA-induced activity and release of excitatory amino acids by dynorphin: Possible roles in paralysis and neurotoxicity. Brain Res. 575:1992;272-278.
    • (1992) Brain Res. , vol.575 , pp. 272-278
    • Skilling, S.R.1    Sun, X.2    Kurtz, H.J.3    Larson, A.A.4
  • 81
    • 0020691952 scopus 로고
    • Extracts of skeletal muscle increase neurite outgrowth and cholinergic activity of fetal rat spinal motor neurons
    • Smith R. G., Appel S. H. Extracts of skeletal muscle increase neurite outgrowth and cholinergic activity of fetal rat spinal motor neurons. Science. 219:1983;1079-1081.
    • (1983) Science , vol.219 , pp. 1079-1081
    • Smith, R.G.1    Appel, S.H.2
  • 82
    • 0025644753 scopus 로고
    • Inhibition of calcium currents by noradrenaline, somatostatin and opioids in guinea-pig submucosal neurons
    • Surprenant A., Shen K.-Z., North R. A. Inhibition of calcium currents by noradrenaline, somatostatin and opioids in guinea-pig submucosal neurons. J. Physiol. 431:1990;585-608.
    • (1990) J. Physiol. , vol.431 , pp. 585-608
    • Surprenant, A.1    Shen, K.-Z.2    North, R.A.3
  • 83
    • 0028122452 scopus 로고
    • Kappa opioids: Therapeutic considerations in epilepsy and CNS injury
    • Tortella F. C., DeCoster M. A. Kappa opioids: Therapeutic considerations in epilepsy and CNS injury. Clin. Neuropharmacol. 17:1994;403-416.
    • (1994) Clin. Neuropharmacol. , vol.17 , pp. 403-416
    • Tortella, F.C.1    Decoster, M.A.2
  • 84
    • 0024205197 scopus 로고
    • The sequential appearance of low- And high-molecular-weight forms of MAP2 in the developing cerebellum
    • Tucker R. P., Binder L. I., Viereck C., Hemmings B. A., Matus A. I. The sequential appearance of low- and high-molecular-weight forms of MAP2 in the developing cerebellum. J. Neurosci. 8:1988;4503-4512.
    • (1988) J. Neurosci. , vol.8 , pp. 4503-4512
    • Tucker, R.P.1    Binder, L.I.2    Viereck, C.3    Hemmings, B.A.4    Matus, A.I.5
  • 85
    • 17344385566 scopus 로고    scopus 로고
    • Single intrathecal injections of dynorphin A or des-Tyr-dynorphins produce long-lasting allodynia in rats: Blockade by MK-801 but not naloxone
    • Vanderah T. W., Laughlin T., Lashbrook J. M., Nichols M. L., Wilcox G. L., Ossipov M. H., Malan T. P. J., Porreca F. Single intrathecal injections of dynorphin A or des-Tyr-dynorphins produce long-lasting allodynia in rats: Blockade by MK-801 but not naloxone. Pain. 68:1996;275-281.
    • (1996) Pain , vol.68 , pp. 275-281
    • Vanderah, T.W.1    Laughlin, T.2    Lashbrook, J.M.3    Nichols, M.L.4    Wilcox, G.L.5    Ossipov, M.H.6    Malan, T.P.J.7    Porreca, F.8
  • 86
    • 0025513852 scopus 로고
    • 2+, bioenergetic state, and neurologic outcome following traumatic brain injury in rats
    • 2+, bioenergetic state, and neurologic outcome following traumatic brain injury in rats. J. Neurosci. 10:1990;3524-3530.
    • (1990) J. Neurosci. , vol.10 , pp. 3524-3530
    • Vink, R.1    McIntosh, T.K.2    Rhomhanyi, R.3    Faden, A.I.4
  • 87
  • 88
    • 0020364689 scopus 로고
    • Dynorphin (1-17): Lack of analgesia but evidence for non-opiate electrophysiological and motor effects
    • Walker J. M., Moises H. C., Coy D. H., Young E. A., Watson S. J., Akil H. Dynorphin (1-17): Lack of analgesia but evidence for non-opiate electrophysiological and motor effects. Life Sci. 31:1982;1821-1824.
    • (1982) Life Sci. , vol.31 , pp. 1821-1824
    • Walker, J.M.1    Moises, H.C.2    Coy, D.H.3    Young, E.A.4    Watson, S.J.5    Akil, H.6
  • 90
    • 0027970357 scopus 로고
    • Bimodal opioid regulation of cyclic AMP formation: Implications for positive and negative coupling of opiate receptors to adenylyl cyclase
    • Wang L., Gintzler A. R. Bimodal opioid regulation of cyclic AMP formation: Implications for positive and negative coupling of opiate receptors to adenylyl cyclase. J. Neurochem. 63:1994;1726-1730.
    • (1994) J. Neurochem. , vol.63 , pp. 1726-1730
    • Wang, L.1    Gintzler, A.R.2
  • 93
    • 0032032480 scopus 로고    scopus 로고
    • Astrocytes protect neurons from neurotoxic injury by serum glutamate
    • Ye Z.-C., Sontheimer H. Astrocytes protect neurons from neurotoxic injury by serum glutamate. Glia. 22:1998;237-248.
    • (1998) Glia , vol.22 , pp. 237-248
    • Ye, Z.-C.1    Sontheimer, H.2
  • 94
    • 0023186731 scopus 로고
    • The degradation of dynorphin A in brain tissue in vivo and in vitro
    • Young E. A., Walker J. M., Houghten R., Akil H. The degradation of dynorphin A in brain tissue in vivo and in vitro. Peptides. 8:1987;701-707.
    • (1987) Peptides , vol.8 , pp. 701-707
    • Young, E.A.1    Walker, J.M.2    Houghten, R.3    Akil, H.4
  • 95
    • 0030805667 scopus 로고    scopus 로고
    • Potentiation of NMDA receptor-mediated responses by dynorphin at low extracellular glycine concentrations
    • Zhang L., Peoples R. W., Oz M., Harvey-White J., Weight F. F., Brauneis U. Potentiation of NMDA receptor-mediated responses by dynorphin at low extracellular glycine concentrations. J. Neurophysiol. 78:1997;582-590.
    • (1997) J. Neurophysiol. , vol.78 , pp. 582-590
    • Zhang, L.1    Peoples, R.W.2    Oz, M.3    Harvey-White, J.4    Weight, F.F.5    Brauneis, U.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.