TRPM7 is required for breast tumor cell metastasis

Cancer Research

Volumn 72, Issue 16, 2012, Pages 4250-4261

  Middelbeek, Jeroen ^a   Kuipers, Arthur J ^a   Henneman, Linda ^c   Visser, Daan ^c   Eidhof, Ilse ^a   Van Horssen, Remco ^a   Wieringa, Bé ^a   Canisius, Sander V ^c   Zwart, Wilbert ^d   Wessels, Lodewyk F ^c   Sweep, Fred C G J ^b   Bult, Peter ^b   Span, Paul N ^b   Van Leeuwen, Frank N ^a   Jalink, Kees ^c  

^a RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

^b RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

^c NETHERLANDS CANCER INSTITUTE   (Netherlands)

^d IMPERIAL CANCER RESEARCH FUND   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

F ACTIN; MESSENGER RNA; MYOSIN II; PAXILLIN; TRANSIENT RECEPTOR POTENTIAL CHANNEL M7; UVOMORULIN;

ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BREAST METASTASIS; BREAST TUMOR; CANCER GROWTH; CANCER PATIENT; CANCER RECURRENCE; CANCER SURVIVAL; CELL ADHESION; CELL MOTION; CELL POLARITY; CELL PROLIFERATION; CELL VIABILITY; CLINICAL ARTICLE; CONTROLLED STUDY; DISTANT METASTASIS; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; METASTASIS POTENTIAL; MOUSE; NONHUMAN; OUTCOME ASSESSMENT; PHENOTYPE; PREDICTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; RECURRENCE FREE SURVIVAL; TRIPLE NEGATIVE BREAST CANCER; TUMOR CELL; TUMOR VOLUME;

ANIMALS; BREAST NEOPLASMS; CELL ADHESION; CELL LINE, TUMOR; CELL MOVEMENT; CYTOSKELETON; DISEASE PROGRESSION; FEMALE; GENE KNOCKDOWN TECHNIQUES; HUMANS; MICE; MICE, TRANSGENIC; NEOPLASM METASTASIS; NEOPLASM STAGING; RECEPTORS, ESTROGEN; RNA, MESSENGER; TRPM CATION CHANNELS;

EID: 84865127930     PISSN: 00085472     EISSN: 15387445     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-11-3863     Document Type: Article

References (40)

1. Bidwell JP, Pavalko FM. Mechanosomes carry a loaded message. Science Signaling 2010;3:pe51.
2. Geiger B, Bershadsky A. Exploring the neighborhood: adhesion-coupled cell mechanosensors. Cell 2002;110:139-42. (Pubitemid 34876542)
3. Parsons JT, Horwitz AR, Schwartz MA. Cell adhesion: integrating cytoskeletal dynamics and cellular tension. Nat Rev 2010;11:633-43.
4. Chen CS, Tan J, Tien J. Mechanotransduction at cell-matrix and cellcell contacts. Annu Rev Biomed Eng 2004;6:275-302.
5. Liu Z, Tan JL, Cohen DM, Yang MT, Sniadecki NJ, Ruiz SA, et al. Mechanical tugging force regulates the size of cell-cell junctions. Proc Natl Acad Sci U S A 2010;107:9944-9.
6. Paszek MJ, Zahir N, Johnson KR, Lakins JN, Rozenberg GI, Gefen A, et al. Tensional homeostasis and the malignant phenotype. Cancer Cell 2005;8:241-54. (Pubitemid 41317594)
7. Clark K, Middelbeek J, van Leeuwen FN. Interplay between TRP channels and the cytoskeleton in health and disease. Eur J Cell Biol 2008;87:631-40.
8. Lin SY, Corey DP. TRP channels in mechanosensation. Curr Opin Neurobiol 2005;15:350-7. (Pubitemid 40806448)
9. Orr AW, Helmke BP, Blackman BR, Schwartz MA. Mechanisms of mechanotransduction. Dev Cell 2006;10:11-20. (Pubitemid 43025673)
10. Numata T, Shimizu T, Okada Y. Direct mechano-stress sensitivity of TRPM7 channel. Cell Physiol Biochem 2007;19:1-8.
11. Oancea E, Wolfe JT, Clapham DE. Functional TRPM7 channels accumulate at the plasma membrane in response to fluid flow. Circ Res 2006;98:245-53.
12. Clark K, Middelbeek J, Lasonder E, Dulyaninova NG, Morrice NA, Ryazanov AG, et al. TRPM7 regulates myosin IIA filament stability and protein localization by heavy chain phosphorylation. J Mol Biol 2008; 378:790-803.
13. Goswami C, Kuhn J, Heppenstall PA, Hucho T. Importance of non-selective cation channel TRPV4 interaction with cytoskeleton and their reciprocal regulations in cultured cells. PLoS One 2010;5:e11654.
14. Clark K, Langeslag M, van Leeuwen B, Ran L, Ryazanov AG, Figdor CG, et al. TRPM7, a novel regulator of actomyosin contractility and cell adhesion. EMBO J 2006;25:290-301. (Pubitemid 43152850)
15. Wei C, Wang X, Chen M, Ouyang K, Song LS, Cheng H. Calcium flickers steer cell migration. Nature 2009;457:901-5.
16. Su LT, Agapito MA, Li M, Simonson WT, Huttenlocher A, Habas R, et al. TRPM7 regulates cell adhesion by controlling the calcium-dependent protease calpain. J Biol Chem 2006;281:11260-70. (Pubitemid 43855551)
17. Loi S, Haibe-Kains B, Desmedt C, Lallemand F, Tutt AM, Gillet C, et al. Definition of clinically distinct molecular subtypes in estrogen receptor-positive breast carcinomas through genomic grade. J Clin Oncol 2007;25:1239-46. (Pubitemid 46640570)
18. Span PN, Waanders E, Manders P, Heuvel JJ, Foekens JA, Watson MA, et al. Mammaglobin is associated with low-grade, steroid receptor-positive breast tumors from postmenopausal patients, and has independent prognostic value for relapse-free survival time. J Clin Oncol 2004;22:691-8. (Pubitemid 41095073)
19. Livak KJ, Schmittgen TD. Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. Methods 2001;25:402-8. (Pubitemid 34164012)
20. Putnam AJ, Cunningham JJ, Pillemer BB, Mooney DJ. External mechanical strain regulates membrane targeting of Rho GTPases by controlling microtubule assembly. Am J Physiol 2003;284:C627-39. (Pubitemid 36237515)
21. Guilbert A, Gautier M, Dhennin-Duthille I, Haren N, Sevestre H, Ouadid-Ahidouch H. Evidence that TRPM7 is required for breast cancer cell proliferation. Am J Physiol 2009;297:C493-502.
22. Jiang J, LiMH, Inoue K, Chu XP, Seeds J, Xiong ZG. Transient receptor potential melastatin 7-like current in human head and neck carcinoma cells: role in cell proliferation. Cancer Res 2007;67:10929-38. (Pubitemid 350145922)
23. Yang S, Zhang JJ, Huang XY. Orai1 and STIM1 are critical for breast tumor cell migration and metastasis. Cancer Cell 2009;15:124-34.
24. Chrzanowska-Wodnicka M, Burridge K. Rho-stimulated contractility drives the formation of stress fibers and focal adhesions. J Cell Biol 1996;133:1403-15. (Pubitemid 26192339)
25. Giannone G, Ronde P, Gaire M, Haiech J, Takeda K. Calcium oscillations trigger focal adhesion disassembly in human U87 astrocytoma cells. J Biol Chem 2002;277:26364-71. (Pubitemid 34967129)
26. Gupton SL, Waterman-Storer CM. Spatiotemporal feedback between actomyosin and focal-adhesion systems optimizes rapid cell migration. Cell 2006;125:1361-74. (Pubitemid 43929092)
27. Barnhart EL, Lee KC, Keren K, Mogilner A, Theriot JA. An adhesion-dependent switch between mechanisms that determine motile cell shape. PLoS Biol 2011;9:e1001059.
28. Wolfenson H, Bershadsky A, Henis YI, Geiger B. Actomyosin-generated tension controls the molecular kinetics of focal adhesions. J Cell Sci 2011;124:1425-32.
29. Aratyn-Schaus Y, Gardel ML. Transient frictional slip between integrin and the ECM in focal adhesions under myosin II tension. Curr Biol 2010;20:1145-53.
30. Chen CL, Chan PC, Wang SH, Pan YR, Chen HC. Elevated expression of protein kinase C delta induces cell scattering upon serum deprivation. J Cell Sci 2010;123:2901-13.
31. Uehata M, Ishizaki T, Satoh H, Ono T, Kawahara T, Morishita T, et al. Calcium sensitization of smooth muscle mediated by a Rho-associated protein kinase in hypertension. Nature 1997;389:990-4. (Pubitemid 27485693)
32. Goodman KB, Cui H, Dowdell SE, Gaitanopoulos DE, Ivy RL, Sehon CA, et al. Development of dihydropyridone indazole amides as selective Rho-kinase inhibitors. J Med Chem 2007;50:6-9. (Pubitemid 46105495)
33. Croft DR, Sahai E, Mavria G, Li S, Tsai J, Lee WM, et al. Conditional ROCK activation in vivo induces tumor cell dissemination and angiogenesis. Cancer Res 2004;64:8994-9001. (Pubitemid 39665509)
34. Jiang P, Enomoto A, Takahashi M. Cell biology of the movement of breast cancer cells: intracellular signalling and the actin cytoskeleton. Cancer Lett 2009;284:122-30.
35. DiMilla PA, Barbee K, Lauffenburger DA. Mathematical model for the effects of adhesion and mechanics on cell migration speed. Biophys J 1991;60:15-37.
36. DiMilla PA, Stone JA, Quinn JA, Albelda SM, Lauffenburger DA. Maximal migration of human smooth muscle cells on fibronectin and type IV collagen occurs at an intermediate attachment strength. J Cell Biol 1993;122:729-37. (Pubitemid 23226689)
37. Pedersen SF, Nilius B. Transient receptor potential channels in mechanosensing and cell volume regulation. Methods Enzymol 2007;428:183-207.
38. Jin J, Desai BN, Navarro B, Donovan A, Andrews NC, Clapham DE. Deletion of Trpm7 disrupts embryonic development and thymopoiesis without altering Mg2 +homeostasis. Science 2008;322:756-60.
39. Clark K, Langeslag M, Figdor CG, van Leeuwen FN. Myosin II and mechanotransduction: a balancing act. Trends Cell Biol 2007;17:178-86. (Pubitemid 46507805)
40. Jaalouk DE, Lammerding J. Mechanotransduction gone awry. Nat Rev 2009;10:63-73.