EGF enhances the migration of cancer cells by up-regulation of TRPM7

Cell Calcium

Volumn 50, Issue 6, 2011, Pages 559-568

  Gao, Haixia ^a   Chen, Xingjuan ^a   Du, Xiaona ^a   Guan, Bingcai ^a   Liu, Yani ^a   Zhang, Hailin ^a  

^a HEBEI MEDICAL UNIVERSITY   (China)

Author keywords

EGF; Lung cancer; Migration; TRPM7

Indexed keywords

CALCIUM ION; EPIDERMAL GROWTH FACTOR; TRANSIENT RECEPTOR POTENTIAL CHANNEL M7;

AMPLITUDE MODULATION; ARTICLE; CANCER CELL; CELL MIGRATION; CONTROLLED STUDY; ELECTROPHYSIOLOGY; HUMAN; HUMAN CELL; HUMAN TISSUE; ION CURRENT; ION TRANSPORT; LUNG CANCER; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; RNA INTERFERENCE; UPREGULATION;

EID: 82855172105     PISSN: 01434160     EISSN: 15321991     Source Type: Journal    
DOI: 10.1016/j.ceca.2011.09.003     Document Type: Article

References (48)

1. Jemal A., Murray T., Samuels A., Ghafoor A., Ward E., Thun M.J. Cancer statistics, 2003. CA Cancer J. Clin. 2003, 53:5-26.
2. Parkin D.M., Bray F.I., Devesa S.S. Cancer burden in the year 2000. The global picture. Eur. J. Cancer 2001, 37(Suppl. 8):S4-S66.
3. Greenlee R.T., Murray T., Bolden S., Wingo P.A. Cancer statistics, 2000. CA Cancer J. Clin. 2000, 50:7-33.
4. Mareel M., Leroy A. Clinical, cellular, and molecular aspects of cancer invasion. Physiol. Rev. 2003, 83:337-376.
5. Entschladen F., Zanker K.S. Locomotion of tumor cells: a molecular comparison to migrating pre- and postmitotic leukocytes. J. Cancer Res. Clin. Oncol. 2000, 126:671-681.
6. 2+ transport. Nat. Rev. Cancer 2007, 7:519-530.
7. Lee J., Ishihara A., Oxford G., Johnson B., Jacobson K. Regulation of cell movement is mediated by stretch-activated calcium channels. Nature 1999, 400:382-386.
8. Wei C., Wang X., Chen M., Ouyang K., Song L.S., Cheng H. Calcium flickers steer cell migration. Nature 2009, 457:901-905.
9. Zaninetti R., Fornarelli A., Ciarletta M., Lim D., Caldarelli A., Pirali T., Cariboni A., Owsianik G., Nilius B., Canonico P.L., Distasi C., Genazzani A.A. Activation of TRPV4 channels reduces migration of immortalized neuroendocrine cells. J. Neurochem. 2011, 116:606-615.
10. Alessandro R., Masiero L., Liotta L.A., Kohn E.C. The role of calcium in the regulation of invasion and angiogenesis. In Vivo 1996, 10:153-160.
11. Montell C. The TRP superfamily of cation channels. Sci. STKE 2005, 2005:re3.
12. Clapham D.E. TRP channels as cellular sensors. Nature 2003, 426:517-524.
13. Santoni G., Farfariello V. TRP channels and cancer: new targets for diagnosis and chemotherapy. Endocr. Metab. Immune Disord. Drug Targets 2011.
14. Heilig E.A., Thompson K.J., Molina R.M., Ivanov A.R., Brain J.D., Wessling-Resnick M. Manganese and iron transport across pulmonary epithelium. Am. J. Physiol. Lung Cell. Mol. Physiol. 2006, 290:L1247-L1259.
15. Nadler M.J., Hermosura M.C., Inabe K., Perraud A.L., Zhu Q., Stokes A.J., Kurosaki T., Kinet J.P., Penner R., Scharenberg A.M., Fleig A. LTRPC7 is a Mg.ATP-regulated divalent cation channel required for cell viability. Nature 2001, 411:590-595.
16. Mederos y Schnitzler M., Waring J., Gudermann T., Chubanov V. Evolutionary determinants of divergent calcium selectivity of TRPM channels. FASEB J. 2008, 22:1540-1551.
17. Abed E., Moreau R. Importance of melastatin-like transient receptor potential 7 and magnesium in the stimulation of osteoblast proliferation and migration by platelet-derived growth factor. Am. J. Physiol. Cell Physiol. 2009, 297:C360-C368.
18. Chen J.P., Luan Y., You C.X., Chen X.H., Luo R.C., Li R. TRPM7 regulates the migration of human nasopharyngeal carcinoma cell by mediating Ca(2+) influx. Cell Calcium 2010, 47:425-432.
19. Normanno N., Bianco C., De Luca A., Maiello M.R., Salomon D.S. Target-based agents against ErbB receptors and their ligands: a novel approach to cancer treatment. Endocr. Relat. Cancer 2003, 10:1-21.
20. Inoue A., Suzuki T., Fukuhara T., Maemondo M., Kimura Y., Morikawa N., Watanabe H., Saijo Y., Nukiwa T. Prospective phase II study of gefitinib for chemotherapy-naive patients with advanced non-small-cell lung cancer with epidermal growth factor receptor gene mutations. J. Clin. Oncol. 2006, 24:3340-3346.
21. Goss G., Ferry D., Wierzbicki R., Laurie S.A., Thompson J., Biesma B., Hirsch F.R., Varella-Garcia M., Duffield E., Ataman O.U., Zarenda M., Armour A.A. Randomized phase II study of gefitinib compared with placebo in chemotherapy-naive patients with advanced non-small-cell lung cancer and poor performance status. J. Clin. Oncol. 2009, 27:2253-2260.
22. Runnels L.W., Yue L., Clapham D.E. TRP-PLIK, a bifunctional protein with kinase and ion channel activities. Science 2001, 291:1043-1047.
23. Guilbert A., Gautier M., Dhennin-Duthille I., Haren N., Sevestre H., Ouadid-Ahidouch H. Evidence that TRPM7 is required for breast cancer cell proliferation. Am. J. Physiol. Cell Physiol. 2009, 297:C493-C502.
24. Jiang J., Li M.H., Inoue K., Chu X.P., Seeds J., Xiong Z.G. Transient receptor potential melastatin 7-like current in human head and neck carcinoma cells: role in cell proliferation. Cancer Res. 2007, 67:10929-10938.
25. 2+ entry pathway in human retinoblastoma cells. J. Pharmacol. Sci. 2004, 95:403-419.
26. 2+ signals confer fibrogenesis in human atrial fibrillation. Circ. Res. 2010, 106:992-1003.
27. Oancea E., Wolfe J.T., Clapham D.E. Functional TRPM7 channels accumulate at the plasma membrane in response to fluid flow. Circ. Res. 2006, 98:245-253.
28. Krapivinsky G., Mochida S., Krapivinsky L., Cibulsky S.M., Clapham D.E. The TRPM7 ion channel functions in cholinergic synaptic vesicles and affects transmitter release. Neuron 2006, 52:485-496.
29. Levitzki A., Gazit A. Tyrosine kinase inhibition: an approach to drug development. Science 1995, 267:1782-1788.
30. Yang S., Zhang J.J., Huang X.Y. Orai1 and STIM1 are critical for breast tumor cell migration and metastasis. Cancer Cell 2009, 15:124-134.
31. 2+ channels controls the trailing tail contraction in growth factor-induced fibroblast cell migration. J. Biol. Chem. 2005, 280:27130-27137.
32. Clark K., Langeslag M., van Leeuwen B., Ran L., Ryazanov A.G., Figdor C.G., Moolenaar W.H., Jalink K., van Leeuwen F.N. TRPM7, a novel regulator of actomyosin contractility and cell adhesion. EMBO J. 2006, 25:290-301.
33. 2+ content and estrogens. J. Am. Soc. Nephrol. 2006, 17:1035-1043.
34. 2+/calmodulin-sensitive TRPM7-like current in hepatoma and hepatocytes. Am. J. Physiol. Gastrointest. Liver Physiol. 2009, 297:G687-G694.
35. Li M., Jiang J., Yue L. Functional characterization of homo- and heteromeric channel kinases TRPM6 and TRPM7. J. Gen. Physiol. 2006, 127:525-537.
36. Riazanova L.V., Pavur K.S., Petrov A.N., Dorovkov M.V., Riazanov A.G. Novel type of signaling molecules: protein kinases covalently linked to ion channels. Mol. Biol. (Mosk) 2001, 35:321-332.
37. He Y., Yao G., Savoia C., Touyz R.M. Transient receptor potential melastatin 7 ion channels regulate magnesium homeostasis in vascular smooth muscle cells: role of angiotensin II. Circ. Res. 2005, 96:207-215.
38. Aarts M.M., Tymianski M. TRPM7 and ischemic CNS injury. Neuroscientist 2005, 11:116-123.
39. Thebault S., Alexander R.T., Tiel Groenestege W.M., Hoenderop J.G., Bindels R.J. EGF increases TRPM6 activity and surface expression. J. Am. Soc. Nephrol.: JASN 2009, 20:78-85.
40. Takeuchi K., Ito F. EGF receptor in relation to tumor development: molecular basis of responsiveness of cancer cells to EGFR-targeting tyrosine kinase inhibitors. FEBS J. 2010, 277:316-326.
41. Kris M.G., Natale R.B., Herbst R.S., Lynch T.J., Prager D., Belani C.P., Schiller J.H., Kelly K., Spiridonidis H., Sandler A., Albain K.S., Cella D., Wolf M.K., Averbuch S.D., Ochs J.J., Kay A.C. Efficacy of gefitinib, an inhibitor of the epidermal growth factor receptor tyrosine kinase, in symptomatic patients with non-small cell lung cancer: a randomized trial. JAMA 2003, 290:2149-2158.
42. Sharma S.V., Bell D.W., Settleman J., Haber D.A. Epidermal growth factor receptor mutations in lung cancer. Nat. Rev. Cancer 2007, 7:169-181.
43. Domingo G., Perez C.A., Velez M., Cudris J., Raez L.E., Santos E.S. EGF receptor in lung cancer: a successful story of targeted therapy. Expert Rev. Anticancer Ther. 2010, 10:1577-1587.
44. Su L.T., Liu W., Chen H.C., Gonzalez-Pagan O., Habas R., Runnels L.W. TRPM7 regulates polarized cell movements. Biochem. J. 2011, 434:513-521.
45. 2+ transporter transient receptor potential melastatin 7 (TRPM7) cation channel by bradykinin in vascular smooth muscle cells. J. Hypertens. 2009, 27:155-166.
46. Matsushita M., Kozak J.A., Shimizu Y., McLachlin D.T., Yamaguchi H., Wei F.Y., Tomizawa K., Matsui H., Chait B.T., Cahalan M.D., Nairn A.C. Channel function is dissociated from the intrinsic kinase activity and autophosphorylation of TRPM7/ChaK1. J. Biol. Chem. 2005, 280:20793-20803.
47. Dorovkov M.V., Ryazanov A.G. Phosphorylation of annexin I by TRPM7 channel-kinase. J. Biol. Chem. 2004, 279:50643-50646.
48. Su L.T., Agapito M.A., Li M., Simonson W.T., Huttenlocher A., Habas R., Yue L., Runnels L.W. TRPM7 regulates cell adhesion by controlling the calcium-dependent protease calpain. J. Biol. Chem. 2006, 281:11260-11270.