The ion channel ASIC1 contributes to visceral but not cutaneous mechanoreceptor function

Gastroenterology

Volumn 127, Issue 6, 2004, Pages 1739-1747

  Page, Amanda J ^a,b   Brierley, Stuart M ^a,b   Martin, Christopher M ^a,b   Martinez Salgado, Carlos ^c   Wemmie, John A ^d   Brennan, Timothy J ^d   Symonds, Erin ^e   Omari, Taher ^b,e   Lewin, Gary R ^c   Welsh, Michael J ^d   Blackshaw, L Ashley ^a,b  

^a HANSON INSTITUTE   (Australia)

^b UNIVERSITY OF ADELAIDE   (Australia)

^c MAX DELBRÜCK CENTER FOR MOLECULAR MEDICINE   (Germany)

^d UNIVERSITY OF IOWA   (United States)

^e WOMEN S AND CHILDREN S HOSPITAL   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

ION CHANNEL; MEMBRANE PROTEIN; MESSENGER RNA; PROTEIN ASIC1; SODIUM CHANNEL; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CARBON DIOXIDE BREATHING; COLON; CONTROLLED STUDY; GASTROINTESTINAL TRACT FUNCTION; MECHANORECEPTOR; MECHANOTRANSDUCTION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; RECEPTOR INTRINSIC ACTIVITY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SENSORY GANGLION; SENSORY NERVE; SKIN RECEPTOR; STIMULUS RESPONSE; STOMACH EMPTYING; THERMAL STIMULATION; VAGUS NERVE; VISCERA; WESTERN BLOTTING; WILD TYPE;

EID: 9644263983     PISSN: 00165085     EISSN: None     Source Type: Journal    
DOI: 10.1053/j.gastro.2004.08.061     Document Type: Article

References (31)

1. W. Schwizer, A. Steingotter, M. Fox, T. Zur, M. Thumshirn, P. Bosiger, M. Fried Non-invasive measurement of gastric accommodation in humans Gut 51 Suppl 1 2002 i59 i62
2. M. Abo, T. Kono, Z. Wang, J.D. Chen Impairment of gastric and jejunal myoelectrical activity during rectal distension in dogs Dig Dis Sci 45 2000 1731 1736
3. H. Abrahamsson, G. Jansson Vago-vagal gastro-gastric relaxation in the cat Acta Physiol Scand 88 1973 289 295
4. W.M. Sun, N.W. Read, A. Prior, J.A. Daly, S.K. Cheah, D. Grundy Sensory and motor responses to rectal distention vary according to rate and pattern of balloon inflation Gastroenterology 99 1990 1008 1015
5. I. Mano, M. Driscoll DEG/ENaC channels a touchy superfamily that watches its salt Bioessays 21 1999 568 578
6. M. Driscoll, M. Chalfie The mec-4 gene is a member of a family of Caenorhabditis elegans genes that can mutate to induce neuronal degeneration Nature 349 1991 588 593
7. H.A. Drummond, F.M. Abboud, M.J. Welsh Localization of beta and gamma subunits of ENaC in sensory nerve endings in the rat foot pad Brain Res 884 2000 1 12
8. M.P. Price, G.R. Lewin, S.L. McIlwrath, C. Cheng, J. Xie, P.A. Heppenstall, C.L. Stucky, A.G. Mannsfeldt, T.J. Brennan, H.A. Drummond, J. Qiao, C.J. Benson, D.E. Tarr, R.F. Hrstka, B. Yang, R.A. Williamson, M.J. Welsh The mammalian sodium channel BNC1 is required for normal touch sensation Nature 407 2000 1007 1011
9. M.P. Price, S.L. McIlwrath, J. Xie, C. Cheng, J. Qiao, D.E. Tarr, K.A. Sluka, T.J. Brennan, G.R. Lewin, M.J. Welsh The DRASIC cation channel contributes to the detection of cutaneous touch and acid stimuli in mice Neuron 32 2001 1071 1083
10. J. Garcia-Anoveros, T.A. Samad, L. Zuvela-Jelaska, C.J. Woolf, D.P. Corey Transport and localization of the DEG/ENaC ion channel BNaC1alpha to peripheral mechanosensory terminals of dorsal root ganglia neurons J Neurosci 21 2001 2678 2686
11. C.C. Chen, A. Zimmer, W.H. Sun, J. Hall, M.J. Brownstein A role for ASIC3 in the modulation of high-intensity pain stimuli Proc Natl Acad Sci U S A 99 2002 8992 8997
12. C.J. Benson, J. Xie, J.A. Wemmie, M.P. Price, J.M. Henss, M.J. Welsh, P.M. Snyder Heteromultimers of DEG/ENaC subunits form H+-gated channels in mouse sensory neurons Proc Natl Acad Sci U S A 99 2002 2338 2343
13. J.A. Wemmie, J. Chen, C.C. Askwith, A.M. Hruska-Hageman, M.P. Price, B.C. Nolan, P.G. Yoder, E. Lamani, T. Hoshi, J.H. Freeman Jr, M.J. Welsh The acid-activated ion channel ASIC contributes to synaptic plasticity, learning, and memory Neuron 34 2002 463 477
14. P.A. Lynn, L.A. Blackshaw In vitro recordings of afferent fibres with receptive fields in the serosa, muscle and mucosa of rat colon J Physiol 518 1999 271 282
15. S.M. Brierley, R.C.W. Jones, G.F. Gebhart, L.A. Blackshaw Splanchnic and pelvic mechanosensory afferents signal different qualities of colonic stimuli in mice Gastroenterology 127 2004 166 178
16. A.J. Page, C.M. Martin, L.A. Blackshaw Vagal mechanoreceptors and chemoreceptors in mouse stomach and esophagus J Neurophysiol 87 2002 2095 2103
17. A.J. Page, L.A. Blackshaw An in vitro study of the properties of vagal afferent fibres innervating the ferret oesophagus and stomach J Physiol 512 1998 907 916
18. P. Carroll, G.R. Lewin, M. Koltzenburg, K.V. Toyka, H. Thoenen A role for BDNF in mechanosensation Nat Neurosci 1 1998 42 46
19. M. Koltzenburg, C.L. Stucky, G.R. Lewin Receptive properties of mouse sensory neurons innervating hairy skin J Neurophysiol 78 1997 1841 1850
20. E.L. Symonds, R.N. Butler, T.I. Omari Assessment of gastric emptying in the mouse using the [13C]-octanoic acid breath test Clin Exp Pharmacol Physiol 27 2000 671 675
21. E. Symonds, R. Butler, T. Omari Noninvasive breath tests can detect alterations in gastric emptying in the mouse Eur J Clin Invest 32 2002 341 344
22. Y.F. Ghoos, B.D. Maes, B.J. Geypens, G. Mys, M.I. Hiele, P.J. Rutgeerts, G. Vantrappen Measurement of gastric emptying rate of solids by means of a carbon-labeled octanoic acid breath test Gastroenterology 104 1993 1640 1647
23. H. Mansikka, M. Shiotani, R. Winchurch, S.N. Raja Neurokinin-1 receptors are involved in behavioral responses to high-intensity heat stimuli and capsaicin-induced hyperalgesia in mice Anesthesiology 90 1999 1643 1649
24. K. Hargreaves, R. Dubner, F. Brown, C. Flores, J. Joris A new and sensitive method for measuring thermal nociception in cutaneous hyperalgesia Pain 32 1988 77 88
25. C.C. Chen, S. England, A.N. Akopian, J.N. Wood A sensory neuron-specific, proton-gated ion channel Proc Natl Acad Sci U S A 95 1998 10240 10245
26. L.A. Blackshaw, G.F. Gebhart The pharmacology of gastrointestinal nociceptive pathways Curr Opin Pharmacol 2 2002 642 649
27. A.J. Page, L.A. Blackshaw GABA(B) receptors inhibit mechanosensitivity of primary afferent endings J Neurosci 19 1999 8597 8602
28. R.K. Mittal, R.H. Holloway, R. Penagini, L.A. Blackshaw, J. Dent Transient lower esophageal sphincter relaxation Gastroenterology 109 1995 601 610
29. M. Camilleri Management of the irritable bowel syndrome Gastroenterology 120 2001 652 668
30. P.L. Andrews, K.L. Wood Vagally mediated gastric motor and emetic reflexes evoked by stimulation of the antral mucosa in anaesthetized ferrets J Physiol 395 1988 1 16
31. L.J. Drew, D.K. Rohrer, M.P. Price, K. Blaver, D.A. Cockayne, P. Cesare, J.N. Wood ASIC2 and ASIC3 do not contribute to mechanically activated currents in mammalian sensory neurons J Physiol 556 2004 691 710