Zn2+ mediates ischemia-induced impairment of the ubiquitin-proteasome system in the rat hippocampus

Journal of Neurochemistry

Volumn 111, Issue 5, 2009, Pages 1094-1103

  Chen, Min ^a   Chen, Qian ^a   Cheng, Xue Wen ^a   Lu, Ting Jia ^a   Liu, Han Xing ^a   Jia, Jie Min ^a   Zhang, Chi ^a   Xu, Li ^a   Xiong, Zhi Qi ^a  

^a INSTITUTE OF GEOLOGY AND GEOPHYSICS   (China)

Author keywords

Global ischemia; Hippocampus; Neurodegeneration; Proteasome; Ubiquitination

Indexed keywords

PHOSPHORYLASE PHOSPHATASE; PROTEASOME; SYNAPTOPHYSIN; UBIQUITIN; ZINC; ZINC CHLORIDE; 4 [4 (4 FLUOROPHENYL) 5 (2 METHOXY 4 PYRIMIDINYL) 1 IMIDAZOLYL]CYCLOHEXANOL; ACTIN; BENZYLOXYCARBONYLLEUCYL LEUCYL LEUCINE ALDEHYDE; BENZYLOXYCARBONYLLEUCYL-LEUCYL-LEUCINE ALDEHYDE; CHELATING AGENT; COUMARIN DERIVATIVE; EDETIC ACID; ENZYME INHIBITOR; FLUORESCENT DYE; GREEN FLUORESCENT PROTEIN; IMIDAZOLE DERIVATIVE; LEUPEPTIN; MICROTUBULE ASSOCIATED PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE P38; OLIGOPEPTIDE; PYRIMIDINE DERIVATIVE; SUCCINYL LEUCYL LEUCYL VALYL TYROSYL METHYLCOUMARINAMIDE; SUCCINYL-LEUCYL-LEUCYL-VALYL-TYROSYL-METHYLCOUMARINAMIDE;

ANIMAL TISSUE; ARTICLE; BRAIN REGION; CELL CULTURE; CONCENTRATION (PARAMETERS); CONJUGATION; CONTROLLED STUDY; DEPLETION; ENZYME ACTIVITY; HIPPOCAMPUS; HOMEOSTASIS; ISCHEMIA; MALE; NERVE DEGENERATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; RAT; UBIQUITINATION; ANIMAL; ANIMAL EMBRYO; CYTOLOGY; DISEASE MODEL; DOSE RESPONSE; DRUG EFFECT; GENETIC TRANSFECTION; GENETICS; METABOLISM; METHODOLOGY; NERVE CELL; NONPARAMETRIC TEST; PATHOLOGY; PATHOPHYSIOLOGY; SPRAGUE DAWLEY RAT; TIME;

RATTUS;

ACTINS; ANIMALS; CA1 REGION, HIPPOCAMPAL; CELLS, CULTURED; CHELATING AGENTS; COUMARINS; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; EDETIC ACID; EMBRYO, MAMMALIAN; ENZYME INHIBITORS; FLUORESCENT DYES; GREEN FLUORESCENT PROTEINS; IMIDAZOLES; ISCHEMIA; LEUPEPTINS; MALE; MICROTUBULE-ASSOCIATED PROTEINS; NEURONS; OLIGOPEPTIDES; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PROTEASOME ENDOPEPTIDASE COMPLEX; PYRIMIDINES; RATS; RATS, SPRAGUE-DAWLEY; STATISTICS, NONPARAMETRIC; TIME FACTORS; TRANSFECTION; UBIQUITIN; ZINC;

EID: 70350786959     PISSN: 00223042     EISSN: 14714159     Source Type: Journal    
DOI: 10.1111/j.1471-4159.2009.06401.x     Document Type: Article

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