메뉴 건너뛰기




Volumn 12, Issue 7, 2011, Pages 388-399

Repertoire of microglial and macrophage responses after spinal cord injury

Author keywords

[No Author keywords available]

Indexed keywords

B7 ANTIGEN; CD163 ANTIGEN; CD45 ANTIGEN; CD86 ANTIGEN; CHEMOKINE RECEPTOR CCR2; CHEMOKINE RECEPTOR CCR6; CHEMOKINE RECEPTOR CX3CR1; COLONY STIMULATING FACTOR 1; CXCL2 CHEMOKINE; CXCL3 CHEMOKINE; FAS ANTIGEN; FAS LIGAND; GAMMA INTERFERON; GAMMA INTERFERON INDUCIBLE PROTEIN 10; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR RECEPTOR; INTERLEUKIN 1; INTERLEUKIN 10; INTERLEUKIN 12; INTERLEUKIN 13; INTERLEUKIN 1BETA; INTERLEUKIN 2; INTERLEUKIN 4; INTERLEUKIN 6; INTERLEUKIN 8; L SELECTIN; MONOCYTE CHEMOTACTIC PROTEIN 1; TUMOR NECROSIS FACTOR ALPHA; TUMOR NECROSIS FACTOR RECEPTOR 1; UNINDEXED DRUG;

EID: 79959379095     PISSN: 1471003X     EISSN: 14710048     Source Type: Journal    
DOI: 10.1038/nrn3053     Document Type: Review
Times cited : (1115)

References (165)
  • 1
    • 78149360132 scopus 로고    scopus 로고
    • Fate mapping analysis reveals that adult microglia derive from primitive macrophages
    • Ginhoux, F. et al. Fate mapping analysis reveals that adult microglia derive from primitive macrophages. Science 330, 841-845 (2010).
    • (2010) Science , vol.330 , pp. 841-845
    • Ginhoux, F.1
  • 2
    • 70349838221 scopus 로고    scopus 로고
    • Taking advantage of the systemic immune system to cure brain diseases
    • Yong, V. W. & Rivest, S. Taking advantage of the systemic immune system to cure brain diseases. Neuron 64, 55-60 (2009).
    • (2009) Neuron , vol.64 , pp. 55-60
    • Yong, V.W.1    Rivest, S.2
  • 3
    • 0036092801 scopus 로고    scopus 로고
    • Targeted disruption of the mouse colony-stimulating factor 1 receptor gene results in osteopetrosis, mononuclear phagocyte deficiency, increased primitive progenitor cell frequencies, and reproductive defects
    • Dai, X. M. et al. Targeted disruption of the mouse colony-stimulating factor 1 receptor gene results in osteopetrosis, mononuclear phagocyte deficiency, increased primitive progenitor cell frequencies, and reproductive defects. Blood 99, 111-120 (2002).
    • (2002) Blood , vol.99 , pp. 111-120
    • Dai, X.M.1
  • 4
    • 0037963473 scopus 로고    scopus 로고
    • Blood monocytes consist of two principal subsets with distinct migratory properties
    • DOI 10.1016/S1074-7613(03)00174-2
    • Geissmann, F., Jung, S. & Littman, D. R. Blood monocytes consist of two principal subsets with distinct migratory properties. Immunity 19, 71-82 (2003). (Pubitemid 36859902)
    • (2003) Immunity , vol.19 , Issue.1 , pp. 71-82
    • Geissmann, F.1    Jung, S.2    Littman, D.R.3
  • 7
    • 0037625155 scopus 로고    scopus 로고
    • TNF/iNOS-producing dendritic cells mediate innate immune defense against bacterial infection
    • DOI 10.1016/S1074-7613(03)00171-7
    • Serbina, N. V., Salazar-Mather, T. P., Biron, C. A., Kuziel, W. A. & Pamer, E. G. TNF/iNOS-producing dendritic cells mediate innate immune defense against bacterial infection. Immunity 19, 59-70 (2003). (Pubitemid 36859901)
    • (2003) Immunity , vol.19 , Issue.1 , pp. 59-70
    • Serbina, N.V.1    Salazar-Mather, T.P.2    Biron, C.A.3    Kuziel, W.A.4    Pamer, E.G.5
  • 8
    • 63449110370 scopus 로고    scopus 로고
    • CX3CR1+ CD115+ CD135+ common macrophage/DC precursors and the role of CX3CR1 in their response to inflammation
    • Auffray, C. et al. CX3CR1+ CD115+ CD135+ common macrophage/DC precursors and the role of CX3CR1 in their response to inflammation. J. Exp. Med. 206, 595-606 (2009).
    • (2009) J. Exp. Med. , vol.206 , pp. 595-606
    • Auffray, C.1
  • 9
    • 33645953640 scopus 로고    scopus 로고
    • Langerhans cells arise from monocytes in vivo
    • Ginhoux, F. et al. Langerhans cells arise from monocytes in vivo. Nature Immunol. 7, 265-273 (2006).
    • (2006) Nature Immunol. , vol.7 , pp. 265-273
    • Ginhoux, F.1
  • 10
    • 35748957798 scopus 로고    scopus 로고
    • Lung macrophages serve as obligatory intermediate between blood monocytes and alveolar macrophages
    • Landsman, L. & Jung, S. Lung macrophages serve as obligatory intermediate between blood monocytes and alveolar macrophages. J. Immunol. 179, 3488-3494 (2007).
    • (2007) J. Immunol. , vol.179 , pp. 3488-3494
    • Landsman, L.1    Jung, S.2
  • 11
    • 33846414364 scopus 로고    scopus 로고
    • Distinct differentiation potential of blood monocyte subsets in the lung
    • Landsman, L., Varol, C. & Jung, S. Distinct differentiation potential of blood monocyte subsets in the lung. J. Immunol. 178, 2000-2007 (2007). (Pubitemid 46233396)
    • (2007) Journal of Immunology , vol.178 , Issue.4 , pp. 2000-2007
    • Landsman, L.1    Varol, C.2    Jung, S.3
  • 14
    • 65149093082 scopus 로고    scopus 로고
    • Circulating Ly-6C+ myeloid precursors migrate to the CNS and play a pathogenic role during autoimmune demyelinating disease
    • King, I. L., Dickendesher, T. L. & Segal, B. M. Circulating Ly-6C+ myeloid precursors migrate to the CNS and play a pathogenic role during autoimmune demyelinating disease. Blood 113, 3190-3197 (2009).
    • (2009) Blood , vol.113 , pp. 3190-3197
    • King, I.L.1    Dickendesher, T.L.2    Segal, B.M.3
  • 15
    • 77950521720 scopus 로고    scopus 로고
    • Astrocytes initiate inflammation in the injured mouse spinal cord by promoting the entry of neutrophils and inflammatory monocytes in an IL-1 receptor/MyD88-dependent fashion
    • Pineau, I., Sun, L., Bastien, D. & Lacroix, S. Astrocytes initiate inflammation in the injured mouse spinal cord by promoting the entry of neutrophils and inflammatory monocytes in an IL-1 receptor/MyD88-dependent fashion. Brain Behav. Immun. 24, 540-553 (2010).
    • (2010) Brain Behav. Immun. , vol.24 , pp. 540-553
    • Pineau, I.1    Sun, L.2    Bastien, D.3    Lacroix, S.4
  • 17
    • 38749086493 scopus 로고    scopus 로고
    • Inflammation and its role in neuroprotection, axonal regeneration and functional recovery after spinal cord injury
    • DOI 10.1016/j.expneurol.2007.06.009, PII S0014488607002518
    • Donnelly, D. J. & Popovich, P. G. Inflammation and its role in neuroprotection, axonal regeneration and functional recovery after spinal cord injury. Exp. Neurol. 209, 378-388 (2008). (Pubitemid 351181428)
    • (2008) Experimental Neurology , vol.209 , Issue.2 , pp. 378-388
    • Donnelly, D.J.1    Popovich, P.G.2
  • 19
    • 33745728329 scopus 로고    scopus 로고
    • Lipoxins and new lipid mediators in the resolution of inflammation
    • Schwab, J. M. & Serhan, C. N. Lipoxins and new lipid mediators in the resolution of inflammation. Curr. Opin. Pharmacol. 6, 414-420 (2006).
    • (2006) Curr. Opin. Pharmacol. , vol.6 , pp. 414-420
    • Schwab, J.M.1    Serhan, C.N.2
  • 20
    • 34250357688 scopus 로고    scopus 로고
    • Resolvin E1 and protectin D1 activate inflammation-resolution programmes
    • DOI 10.1038/nature05877, PII NATURE05877
    • Schwab, J. M., Chiang, N., Arita, M. & Serhan, C. N. Resolvin E1 and protectin D1 activate inflammation-resolution programmes. Nature 447, 869-874 (2007). (Pubitemid 46920139)
    • (2007) Nature , vol.447 , Issue.7146 , pp. 869-874
    • Schwab, J.M.1    Chiang, N.2    Arita, M.3    Serhan, C.N.4
  • 21
    • 79959373621 scopus 로고    scopus 로고
    • Non-resolving aspects of acute inflammation after spinal cord injury (SCI): Indices and resolution plateau
    • 24 Apr doi:10.1111/j.1750-3639.2011.00488.x
    • Prüss, H. et al. Non-resolving aspects of acute inflammation after spinal cord injury (SCI): indices and resolution plateau. Brain Pathol. 24 Apr 2011 (doi:10.1111/j.1750-3639.2011.00488.x).
    • (2011) Brain Pathol
    • Prüss, H.1
  • 22
  • 23
    • 33646844063 scopus 로고    scopus 로고
    • Omega-3 fatty acids improve recovery, whereas omega-6 fatty acids worsen outcome, after spinal cord injury in the adult rat
    • DOI 10.1523/JNEUROSCI.5539-05.2006
    • King, V. R. et al. Omega-3 fatty acids improve recovery, whereas omega-6 fatty acids worsen outcome, after spinal cord injury in the adult rat. J. Neurosci. 26, 4672-4680 (2006). (Pubitemid 44315368)
    • (2006) Journal of Neuroscience , vol.26 , Issue.17 , pp. 4672-4680
    • King, V.R.1    Huang, W.L.2    Dyall, S.C.3    Curran, O.E.4    Priestley, J.V.5    Michael-Titus, A.T.6
  • 24
  • 25
    • 78649418163 scopus 로고    scopus 로고
    • The acute administration of eicosapentaenoic acid is neuroprotective after spinal cord compression injury in rats
    • Lim, S. N. et al. The acute administration of eicosapentaenoic acid is neuroprotective after spinal cord compression injury in rats. Prostaglandins Leukot. Essent. Fatty Acids 83, 193-201 (2010).
    • (2010) Prostaglandins Leukot. Essent. Fatty Acids , vol.83 , pp. 193-201
    • Lim, S.N.1
  • 26
    • 77749313475 scopus 로고    scopus 로고
    • Fenretinide promotes functional recovery and tissue protection after spinal cord contusion injury in mice
    • López-Vales, R. et al. Fenretinide promotes functional recovery and tissue protection after spinal cord contusion injury in mice. J. Neurosci. 30, 3220-3226 (2010).
    • (2010) J. Neurosci. , vol.30 , pp. 3220-3226
    • López-Vales, R.1
  • 27
    • 31544446571 scopus 로고    scopus 로고
    • + immature myeloid suppressor cells mediate the development of tumor-induced T regulatory cells and T-cell anergy in tumor-bearing host
    • DOI 10.1158/0008-5472.CAN-05-1299
    • Huang, B. et al. Gr-1+CD115+ immature myeloid suppressor cells mediate the development of tumor-induced T regulatory cells and T-cell anergy in tumor-bearing host. Cancer Res. 66, 1123-1131 (2006). (Pubitemid 43165981)
    • (2006) Cancer Research , vol.66 , Issue.2 , pp. 1123-1131
    • Huang, B.1    Pan, P.-Y.2    Li, Q.3    Sato, A.I.4    Levy, D.E.5    Bromberg, J.6    Divino, C.M.7    Chen, S.-H.8
  • 28
    • 77954641353 scopus 로고    scopus 로고
    • Normal human monocytes exposed to glioma cells acquire myeloid-derived suppressor cell-like properties
    • Rodrigues, J. C. et al. Normal human monocytes exposed to glioma cells acquire myeloid-derived suppressor cell-like properties. Neuro Oncol. 12, 351-365 (2010).
    • (2010) Neuro Oncol. , vol.12 , pp. 351-365
    • Rodrigues, J.C.1
  • 31
    • 67649404131 scopus 로고    scopus 로고
    • Blood monocytes: Development, heterogeneity, and relationship with dendritic cells
    • Auffray, C., Sieweke, M. H. & Geissmann, F. Blood monocytes: development, heterogeneity, and relationship with dendritic cells. Annu. Rev. Immunol. 27, 669-692 (2009).
    • (2009) Annu. Rev. Immunol. , vol.27 , pp. 669-692
    • Auffray, C.1    Sieweke, M.H.2    Geissmann, F.3
  • 34
    • 78650632751 scopus 로고    scopus 로고
    • M2b monocytes predominated in peripheral blood of severely burned patients
    • Kobayashi, M. et al. M2b monocytes predominated in peripheral blood of severely burned patients. J. Immunol. 185, 7174-7179 (2010).
    • (2010) J. Immunol. , vol.185 , pp. 7174-7179
    • Kobayashi, M.1
  • 35
    • 78651473243 scopus 로고    scopus 로고
    • Neuroprotection and progenitor cell renewal in the injured adult murine retina requires healing monocyte-derived macrophages
    • London, A. et al. Neuroprotection and progenitor cell renewal in the injured adult murine retina requires healing monocyte-derived macrophages. J. Exp. Med. 208, 23-39 (2011).
    • (2011) J. Exp. Med. , vol.208 , pp. 23-39
    • London, A.1
  • 36
    • 68049143269 scopus 로고    scopus 로고
    • Infiltrating blood-derived macrophages are vital cells playing an anti-inflammatory role in recovery from spinal cord injury in mice
    • Shechter, R. et al. Infiltrating blood-derived macrophages are vital cells playing an anti-inflammatory role in recovery from spinal cord injury in mice. PLoS Med. 6, e1000113 (2009).
    • (2009) PLoS Med. , vol.6
    • Shechter, R.1
  • 38
    • 70449650338 scopus 로고    scopus 로고
    • Microglia processes block the spread of damage in the brain and require functional chloride channels
    • Hines, D. J., Hines, R. M., Mulligan, S. J. & Macvicar, B. A. Microglia processes block the spread of damage in the brain and require functional chloride channels. Glia 57, 1610-1618 (2009).
    • (2009) Glia , vol.57 , pp. 1610-1618
    • Hines, D.J.1    Hines, R.M.2    Mulligan, S.J.3    MacVicar, B.A.4
  • 40
    • 34249057095 scopus 로고    scopus 로고
    • ATP-induced chemotaxis of microglial processes requires P2Y receptor-activated initiation of outward potassium currents
    • DOI 10.1002/glia.20500
    • Wu, L. J., Vadakkan, K. I. & Zhuo, M. ATP-induced chemotaxis of microglial processes requires P2Y receptor-activated initiation of outward potassium currents. Glia 55, 810-821 (2007). (Pubitemid 46787192)
    • (2007) GLIA , vol.55 , Issue.8 , pp. 810-821
    • Wu, L.-J.1    Vadakkan, K.I.2    Zhuo, M.3
  • 41
    • 77952573195 scopus 로고    scopus 로고
    • P2Y12 receptor-mediated integrin-β1 activation regulates microglial process extension induced by ATP
    • Ohsawa, K. et al. P2Y12 receptor-mediated integrin-β1 activation regulates microglial process extension induced by ATP. Glia 58, 790-801 (2010).
    • (2010) Glia , vol.58 , pp. 790-801
    • Ohsawa, K.1
  • 42
    • 69449086036 scopus 로고    scopus 로고
    • P2 receptor-mediated stimulation of the PI3-K/Akt-pathway in vivo
    • Franke, H. et al. P2 receptor-mediated stimulation of the PI3-K/Akt-pathway in vivo. Glia 57, 1031-1045 (2009).
    • (2009) Glia , vol.57 , pp. 1031-1045
    • Franke, H.1
  • 43
    • 43149123118 scopus 로고    scopus 로고
    • Akt activation is involved in P2Y12 receptor-mediated chemotaxis of microglia
    • DOI 10.1002/jnr.21610
    • Irino, Y., Nakamura, Y., Inoue, K., Kohsaka, S. & Ohsawa, K. Akt activation is involved in P2Y12 receptor-mediated chemotaxis of microglia. J. Neurosci. Res. 86, 1511-1519 (2008). (Pubitemid 351642444)
    • (2008) Journal of Neuroscience Research , vol.86 , Issue.7 , pp. 1511-1519
    • Irino, Y.1    Nakamura, Y.2    Inoue, K.3    Kohsaka, S.4    Ohsawa, K.5
  • 44
    • 70349232398 scopus 로고    scopus 로고
    • Regulation of dynamic behavior of retinal microglia by CX3CR1 signaling
    • Liang, K. J. et al. Regulation of dynamic behavior of retinal microglia by CX3CR1 signaling. Invest. Ophthalmol. Vis. Sci. 50, 4444-4451 (2009).
    • (2009) Invest. Ophthalmol. Vis. Sci. , vol.50 , pp. 4444-4451
    • Liang, K.J.1
  • 45
    • 77954398133 scopus 로고    scopus 로고
    • NO mediates microglial response to acute spinal cord injury under ATP control in vivo
    • Dibaj, P. et al. NO mediates microglial response to acute spinal cord injury under ATP control in vivo. Glia 58, 1133-1144 (2010).
    • (2010) Glia , vol.58 , pp. 1133-1144
    • Dibaj, P.1
  • 46
    • 67650966680 scopus 로고    scopus 로고
    • Microglial physiology: Unique stimuli, specialized responses
    • Ransohoff, R. M. & Perry, V. H. Microglial physiology: unique stimuli, specialized responses. Annu. Rev. Immunol. 27, 119-145 (2009).
    • (2009) Annu. Rev. Immunol. , vol.27 , pp. 119-145
    • Ransohoff, R.M.1    Perry, V.H.2
  • 47
    • 33846585119 scopus 로고    scopus 로고
    • Systemic infections and inflammation affect chronic neurodegeneration
    • DOI 10.1038/nri2015, PII NRI2015
    • Perry, V. H., Cunningham, C. & Holmes, C. Systemic infections and inflammation affect chronic neurodegeneration. Nature Rev. Immunol. 7, 161-167 (2007). (Pubitemid 46174862)
    • (2007) Nature Reviews Immunology , vol.7 , Issue.2 , pp. 161-167
    • Perry, V.H.1    Cunningham, C.2    Holmes, C.3
  • 48
    • 36048991728 scopus 로고    scopus 로고
    • Expression of CCR2 in both resident and bone marrow-derived microglia plays a critical role in neuropathic pain
    • DOI 10.1523/JNEUROSCI.3016-07.2007
    • Zhang, J. et al. Expression of CCR2 in both resident and bone marrow-derived microglia plays a critical role in neuropathic pain. J. Neurosci. 27, 12396-12406 (2007). (Pubitemid 350085465)
    • (2007) Journal of Neuroscience , vol.27 , Issue.45 , pp. 12396-12406
    • Zhang, J.1    Xiang, Q.S.2    Echeverry, S.3    Mogil, J.S.4    De Koninck, Y.5    Rivest, S.6
  • 49
    • 65449143227 scopus 로고    scopus 로고
    • Monocyte chemoattractant protein-1 (MCP-1) produced via NF-κB signaling pathway mediates migration of amoeboid microglia in the periventricular white matter in hypoxic neonatal rats
    • Deng, Y. Y., Lu, J., Ling, E. A. & Kaur, C. Monocyte chemoattractant protein-1 (MCP-1) produced via NF-κB signaling pathway mediates migration of amoeboid microglia in the periventricular white matter in hypoxic neonatal rats. Glia 57, 604-621 (2009).
    • (2009) Glia , vol.57 , pp. 604-621
    • Deng, Y.Y.1    Lu, J.2    Ling, E.A.3    Kaur, C.4
  • 50
    • 0035479007 scopus 로고    scopus 로고
    • AIF-1 expression defines a proliferating and alert microglial/macrophage phenotype following spinal cord injury in rats
    • DOI 10.1016/S0165-5728(01)00375-7, PII S0165572801003757
    • Schwab, J. M. et al. AIF-1 expression defines a proliferating and alert microglial/macrophage phenotype following spinal cord injury in rats. J. Neuroimmunol. 119, 214-222 (2001). (Pubitemid 32918329)
    • (2001) Journal of Neuroimmunology , vol.119 , Issue.2 , pp. 214-222
    • Schwab, J.M.1    Frei, E.2    Klusman, I.3    Schnell, L.4    Schwab, M.E.5    Schluesener, H.J.6
  • 51
    • 47749106032 scopus 로고    scopus 로고
    • Origin of CD11b+ macrophage-like cells in the CNS of PLP-overexpressing mice: Low influx of haematogenous macrophages and unchanged blood-brain-barrier in the optic nerve
    • Ip, C. W. et al. Origin of CD11b+ macrophage-like cells in the CNS of PLP-overexpressing mice: low influx of haematogenous macrophages and unchanged blood-brain-barrier in the optic nerve. Mol. Cell Neurosci. 38, 489-494 (2008).
    • (2008) Mol. Cell Neurosci. , vol.38 , pp. 489-494
    • Ip, C.W.1
  • 53
    • 33751102165 scopus 로고    scopus 로고
    • Sialoadhesin deficiency ameliorates myelin degeneration and axonopathic changes in the CNS of PLP overexpressing mice
    • DOI 10.1016/j.nbd.2006.08.023, PII S0969996106002166
    • Ip, C. W., Kroner, A., Crocker, P. R., Nave, K. A. & Martini, R. Sialoadhesin deficiency ameliorates myelin degeneration and axonopathic changes in the CNS of PLP overexpressing mice. Neurobiol. Dis. 25, 105-111 (2007). (Pubitemid 44765220)
    • (2007) Neurobiology of Disease , vol.25 , Issue.1 , pp. 105-111
    • Ip, C.W.1    Kroner, A.2    Crocker, P.R.3    Nave, K.-A.4    Martini, R.5
  • 54
    • 0031815859 scopus 로고    scopus 로고
    • Identification of glial cell proliferation in early multiple sclerosis lesions
    • DOI 10.1046/j.1365-2990.1998.00131.x
    • Schonrock, L. M., Kuhlmann, T., Adler, S., Bitsch, A. & Bruck, W. Identification of glial cell proliferation in early multiple sclerosis lesions. Neuropathol. Appl. Neurobiol. 24, 320-330 (1998). (Pubitemid 28389129)
    • (1998) Neuropathology and Applied Neurobiology , vol.24 , Issue.4 , pp. 320-330
    • Schonrock, L.M.1    Kuhlmann, T.2    Adler, S.3    Bitsch, A.4    Bruck, W.5
  • 55
    • 0017644173 scopus 로고
    • 3H-uridine into rats
    • Imamoto, K. & Leblond, C. P. Presence of labeled monocytes, macrophages and microglia in a stab wound of the brain following an injection of bone marrow cells labeled with 3H-uridine into rats. J. Comp. Neurol. 174, 255-279 (1977). (Pubitemid 8120313)
    • (1977) Journal of Comparative Neurology , vol.174 , Issue.2 , pp. 255-279
    • Imamoto, K.1    Leblond, C.P.2
  • 56
    • 0034946614 scopus 로고    scopus 로고
    • Bone marrow chimeric rats reveal the unique distribution of resident and recruited macrophages in the contused rat spinal cord
    • Popovich, P. G. & Hickey, W. F. Bone marrow chimeric rats reveal the unique distribution of resident and recruited macrophages in the contused rat spinal cord. J. Neuropathol. Exp. Neurol. 60, 676-685 (2001). (Pubitemid 32619790)
    • (2001) Journal of Neuropathology and Experimental Neurology , vol.60 , Issue.7 , pp. 676-685
    • Popovich, P.G.1    Hickey, W.F.2
  • 57
    • 0032838089 scopus 로고    scopus 로고
    • Depletion of hematogenous macrophages promotes partial hindlimb recovery and neuroanatomical repair after experimental spinal cord injury
    • DOI 10.1006/exnr.1999.7118
    • Popovich, P. G. et al. Depletion of hematogenous macrophages promotes partial hindlimb recovery and neuroanatomical repair after experimental spinal cord injury. Exp. Neurol. 158, 351-365 (1999). (Pubitemid 29382826)
    • (1999) Experimental Neurology , vol.158 , Issue.2 , pp. 351-365
    • Popovich, P.G.1    Guan, Z.2    Wei, P.3    Huitinga, I.4    Van Rooijen, N.5    Stokes, B.T.6
  • 58
    • 0345491876 scopus 로고    scopus 로고
    • Caught in the act: In vivo mapping of macrophage infiltration in nerve injury by magnetic resonance imaging
    • Bendszus, M. & Stoll, G. Caught in the act: in vivo mapping of macrophage infiltration in nerve injury by magnetic resonance imaging. J. Neurosci. 23, 10892-10896 (2003). (Pubitemid 37499698)
    • (2003) Journal of Neuroscience , vol.23 , Issue.34 , pp. 10892-10896
    • Bendszus, M.1    Stoll, G.2
  • 59
    • 33747157935 scopus 로고    scopus 로고
    • Fate of endogenous stem/progenitor cells following spinal cord injury
    • DOI 10.1002/cne.21065
    • Horky, L. L., Galimi, F., Gage, F. H. & Horner, P. J. Fate of endogenous stem/progenitor cells following spinal cord injury. J. Comp. Neurol. 498, 525-538 (2006). (Pubitemid 44232692)
    • (2006) Journal of Comparative Neurology , vol.498 , Issue.4 , pp. 525-538
    • Horky, L.L.1    Galimi, F.2    Gage, F.H.3    Horner, P.J.4
  • 60
    • 37849004130 scopus 로고    scopus 로고
    • Delayed accumulation of activated macrophages and inhibition of remyelination after spinal cord injury in an adult rodent model
    • Imai, M. et al. Delayed accumulation of activated macrophages and inhibition of remyelination after spinal cord injury in an adult rodent model. J. Neurosurg. Spine 8, 58-66 (2008).
    • (2008) J. Neurosurg. Spine , vol.8 , pp. 58-66
    • Imai, M.1
  • 61
    • 33845568271 scopus 로고    scopus 로고
    • Proinflammatory cytokine synthesis in the injured mouse spinal cord: Multiphasic expression pattern and identification of the cell types involved
    • DOI 10.1002/cne.21149
    • Pineau, I. & Lacroix, S. Proinflammatory cytokine synthesis in the injured mouse spinal cord: multiphasic expression pattern and identification of the cell types involved. J. Comp. Neurol. 500, 267-285 (2007). (Pubitemid 44937122)
    • (2007) Journal of Comparative Neurology , vol.500 , Issue.2 , pp. 267-285
    • Pineau, I.1    Lacroix, S.2
  • 62
    • 2342596444 scopus 로고    scopus 로고
    • Early expression and cellular localization of proinflammatory cytokines interleukin-1β, interleukin-6, and tumor necrosis factor-α in human traumatic spinal cord injury
    • DOI 10.1097/00007632-200405010-00004
    • Yang, L. et al. Early expression and cellular localization of proinflammatory cytokines interleukin-1β, interleukin-6, and tumor necrosis factor-α in human traumatic spinal cord injury. Spine 29, 966-971 (2004). (Pubitemid 38580232)
    • (2004) Spine , vol.29 , Issue.9 , pp. 966-971
    • Yang, L.1    Blumbergs, P.C.2    Jones, N.R.3    Manavis, J.4    Sarvestani, G.T.5    Ghabriel, M.N.6
  • 65
    • 56149092503 scopus 로고    scopus 로고
    • Cell death after spinal cord injury is exacerbated by rapid TNF α-induced trafficking of GluR2-lacking AMPARs to the plasma membrane
    • Ferguson, A. R. et al. Cell death after spinal cord injury is exacerbated by rapid TNF α-induced trafficking of GluR2-lacking AMPARs to the plasma membrane. J. Neurosci. 28, 11391-11400 (2008).
    • (2008) J. Neurosci. , vol.28 , pp. 11391-11400
    • Ferguson, A.R.1
  • 66
    • 0033775139 scopus 로고    scopus 로고
    • TNFR1 signalling is critical for the development of demyelination and the limitation of T-cell responses during immune-mediated CNS disease
    • Probert, L. et al. TNFR1 signalling is critical for the development of demyelination and the limitation of T-cell responses during immune-mediated CNS disease. Brain 123 (Pt 10), 2005-2019 (2000).
    • (2000) Brain , vol.123 , Issue.PART 10 , pp. 2005-2019
    • Probert, L.1
  • 67
    • 37549029154 scopus 로고    scopus 로고
    • TNF-α blockage in a mouse model of SCI: Evidence for improved outcome
    • Genovese, T. et al. TNF-α blockage in a mouse model of SCI: evidence for improved outcome. Shock 29, 32-41 (2008).
    • (2008) Shock , vol.29 , pp. 32-41
    • Genovese, T.1
  • 68
    • 76949101422 scopus 로고    scopus 로고
    • CD95-ligand on peripheral myeloid cells activates Syk kinase to trigger their recruitment to the inflammatory site
    • Letellier, E. et al. CD95-ligand on peripheral myeloid cells activates Syk kinase to trigger their recruitment to the inflammatory site. Immunity 32, 240-252 (2010).
    • (2010) Immunity , vol.32 , pp. 240-252
    • Letellier, E.1
  • 71
    • 79958055211 scopus 로고    scopus 로고
    • A combination immunomodulatory treatment promotes neuroprotection and locomotor recovery after contusion SCI
    • 23 Mar doi:10.1016/j.expneurol.2010.03.010
    • Iannotti, C. A. et al. A combination immunomodulatory treatment promotes neuroprotection and locomotor recovery after contusion SCI. Exp. Neurol. 23 Mar 2010 (doi:10.1016/j.expneurol.2010.03.010).
    • (2010) Exp. Neurol.
    • Iannotti, C.A.1
  • 73
    • 33846122620 scopus 로고    scopus 로고
    • + channel KCNN4/KCa3.1 contributes to microglia activation and nitric oxide-dependent neurodegeneration
    • DOI 10.1523/JNEUROSCI.3593-06.2007
    • Kaushal, V., Koeberle, P. D., Wang, Y. & Schlichter, L. C. The Ca2+-activated K+ channel KCNN4/KCa3.1 contributes to microglia activation and nitric oxide-dependent neurodegeneration. J. Neurosci. 27, 234-244 (2007). (Pubitemid 46089977)
    • (2007) Journal of Neuroscience , vol.27 , Issue.1 , pp. 234-244
    • Kaushal, V.1    Koeberle, P.D.2    Wang, Y.3    Schlichter, L.C.4
  • 74
    • 39849083520 scopus 로고    scopus 로고
    • Mechanisms of microglia-mediated neurotoxicity in a new model of the stroke penumbra
    • DOI 10.1523/JNEUROSCI.5643-07.2008
    • Kaushal, V. & Schlichter, L. C. Mechanisms of microglia-mediated neurotoxicity in a new model of the stroke penumbra. J. Neurosci. 28, 2221-2230 (2008). (Pubitemid 351317617)
    • (2008) Journal of Neuroscience , vol.28 , Issue.9 , pp. 2221-2230
    • Kaushal, V.1    Schlichter, L.C.2
  • 75
    • 0036264281 scopus 로고    scopus 로고
    • Temporal and segmental distribution of constitutive and inducible nitric oxide synthases after traumatic spinal cord injury: Effect of aminoguanidine treatment
    • Chatzipanteli, K. et al. Temporal and segmental distribution of constitutive and inducible nitric oxide synthases after traumatic spinal cord injury: effect of aminoguanidine treatment. J. Neurotrauma 19, 639-651 (2002). (Pubitemid 34587306)
    • (2002) Journal of Neurotrauma , vol.19 , Issue.5 , pp. 639-651
    • Chatzipanteli, K.1    Garcia, R.2    Marcillo, A.E.3    Loor, K.E.4    Kraydieh, S.5    Dietrich, W.D.6
  • 76
    • 4143113383 scopus 로고    scopus 로고
    • Increased expression of cyclo-oxygenase 2 and vascular endothelial growth factor in lesioned spinal cord by transplanted olfactory ensheathing cells
    • DOI 10.1089/0897715041651105
    • Lσpez-Vales, R., Garcia-Alias, G., Fores, J., Navarro, X. & Verdu, E. Increased expression of cyclo-oxygenase 2 and vascular endothelial growth factor in lesioned spinal cord by transplanted olfactory ensheathing cells. J. Neurotrauma 21, 1031-1043 (2004). (Pubitemid 39096853)
    • (2004) Journal of Neurotrauma , vol.21 , Issue.8 , pp. 1031-1043
    • Lopez-Vales, R.1    Garcia-Alias, G.2    Fores, J.3    Navarro, X.4    Verdu, E.5
  • 79
    • 52549109505 scopus 로고    scopus 로고
    • Role of CX3CR1 (fractalkine receptor) in brain damage and inflammation induced by focal cerebral ischemia in mouse
    • Denes, A., Ferenczi, S., Halasz, J., Kornyei, Z. & Kovacs, K. J. Role of CX3CR1 (fractalkine receptor) in brain damage and inflammation induced by focal cerebral ischemia in mouse. J. Cereb. Blood Flow Metab. 28, 1707-1721 (2008).
    • (2008) J. Cereb. Blood Flow Metab. , vol.28 , pp. 1707-1721
    • Denes, A.1    Ferenczi, S.2    Halasz, J.3    Kornyei, Z.4    Kovacs, K.J.5
  • 81
    • 77957316313 scopus 로고    scopus 로고
    • CX3CR1 deficiency alters microglial activation and reduces β-amyloid deposition in two Alzheimer's disease mouse models
    • Lee, S. et al. CX3CR1 deficiency alters microglial activation and reduces β-amyloid deposition in two Alzheimer's disease mouse models. Am. J. Pathol. 177, 2549-2562 (2010).
    • (2010) Am. J. Pathol. , vol.177 , pp. 2549-2562
    • Lee, S.1
  • 83
    • 14244268775 scopus 로고    scopus 로고
    • Clearance of apoptotic neurons without inflammation by microglial triggering receptor expressed on myeloid cells-2
    • DOI 10.1084/jem.20041611
    • Takahashi, K., Rochford, C. D. & Neumann, H. Clearance of apoptotic neurons without inflammation by microglial triggering receptor expressed on myeloid cells-2. J. Exp. Med. 201, 647-657 (2005). (Pubitemid 40289554)
    • (2005) Journal of Experimental Medicine , vol.201 , Issue.4 , pp. 647-657
    • Takahashi, K.1    Rochford, C.D.P.2    Neumann, H.3
  • 84
    • 33847162723 scopus 로고    scopus 로고
    • A role for nogo receptor in macrophage clearance from injured peripheral nerve
    • DOI 10.1016/j.neuron.2007.02.009, PII S0896627307001080
    • Fry, E. J., Ho, C. & David, S. A role for Nogo receptor in macrophage clearance from injured peripheral nerve. Neuron 53, 649-662 (2007). (Pubitemid 46283376)
    • (2007) Neuron , vol.53 , Issue.5 , pp. 649-662
    • Fry, E.J.1    Ho, C.2    David, S.3
  • 86
    • 42749084557 scopus 로고    scopus 로고
    • Novel roles for Nogo receptor in inflammation and disease
    • David, S., Fry, E. J. & Lopez-Vales, R. Novel roles for Nogo receptor in inflammation and disease. Trends Neurosci. 31, 221-226 (2008).
    • (2008) Trends Neurosci. , vol.31 , pp. 221-226
    • David, S.1    Fry, E.J.2    Lopez-Vales, R.3
  • 87
    • 9644272471 scopus 로고    scopus 로고
    • Molecular mechanisms responsible for microglia-derived protection of Sprague-Dawley rat brain cells during in vitro ischemia
    • Lu, Y. Z., Lin, C. H., Cheng, F. C. & Hsueh, C. M. Molecular mechanisms responsible for microglia-derived protection of Sprague-Dawley rat brain cells during in vitro ischemia. Neurosci. Lett. 373, 159-164 (2005).
    • (2005) Neurosci. Lett. , vol.373 , pp. 159-164
    • Lu, Y.Z.1    Lin, C.H.2    Cheng, F.C.3    Hsueh, C.M.4
  • 88
    • 0027508314 scopus 로고
    • Expression of transforming growth factor-β 1 and interleukin-1 β mRNA in rat brain following transient forebrain ischemia
    • Wiessner, C. et al. Expression of transforming growth factor-β 1 and interleukin-1 β mRNA in rat brain following transient forebrain ischemia. Acta Neuropathol. 86, 439-446 (1993).
    • (1993) Acta Neuropathol. , vol.86 , pp. 439-446
    • Wiessner, C.1
  • 89
    • 18244388464 scopus 로고    scopus 로고
    • Microglia overexpressing the macrophage colony-stimulating factor receptor are neuroprotective in a microglial-hippocampal organotypic coculture system
    • DOI 10.1523/JNEUROSCI.0514-05.2005
    • Mitrasinovic, O. M. et al. Microglia overexpressing the macrophage colony-stimulating factor receptor are neuroprotective in a microglial- hippocampal organotypic coculture system. J. Neurosci. 25, 4442-4451 (2005). (Pubitemid 40628788)
    • (2005) Journal of Neuroscience , vol.25 , Issue.17 , pp. 4442-4451
    • Mitrasinovic, O.M.1    Grattan, A.2    Robinson, C.C.3    Lapustea, N.B.4    Poon, C.5    Ryan, H.6    Phong, C.7    Murphy Jr., G.M.8
  • 90
    • 58849147077 scopus 로고    scopus 로고
    • Dendritic cell differentiation signals induce anti-inflammatory properties in human adult microglia
    • Lambert, C. et al. Dendritic cell differentiation signals induce anti-inflammatory properties in human adult microglia. J. Immunol. 181, 8288-8297 (2008).
    • (2008) J. Immunol. , vol.181 , pp. 8288-8297
    • Lambert, C.1
  • 91
    • 33845667413 scopus 로고    scopus 로고
    • Delayed GM-CSF treatment stimulates axonal regeneration and functional recovery in paraplegic rats via an increased BDNF expression by endogenous macrophages
    • Bouhy, D. et al. Delayed GM-CSF treatment stimulates axonal regeneration and functional recovery in paraplegic rats via an increased BDNF expression by endogenous macrophages. FASEB J. 20, 1239-1241 (2006).
    • (2006) FASEB J. , vol.20 , pp. 1239-1241
    • Bouhy, D.1
  • 92
    • 13844254470 scopus 로고    scopus 로고
    • Role of granulocyte-macrophage colony-stimulating factor in preventing apoptosis and improving functional outcome in experimental spinal cord contusion injury
    • Ha, Y. et al. Role of granulocyte-macrophage colony-stimulating factor in preventing apoptosis and improving functional outcome in experimental spinal cord contusion injury. J. Neurosurg. Spine 2, 55-61 (2005).
    • (2005) J. Neurosurg. Spine , vol.2 , pp. 55-61
    • Ha, Y.1
  • 94
    • 0032907709 scopus 로고    scopus 로고
    • Potential repair of rat spinal cord injuries using stimulated homologous macrophages
    • discussion 1045-1046
    • Schwartz, M. et al. Potential repair of rat spinal cord injuries using stimulated homologous macrophages. Neurosurgery 44, 1041-1045; discussion 1045-1046 (1999).
    • (1999) Neurosurgery , vol.44 , pp. 1041-1045
    • Schwartz, M.1
  • 96
    • 0032210917 scopus 로고    scopus 로고
    • Peripheral nerve-stimulated macrophages simulate a peripheral nerve-like regenerative response in rat transected optic nerve
    • DOI 10.1002/(SICI)1098-1136(199811)24:3<329::AID-GLIA7>3.0.CO;2-X
    • Lazarov-Spiegler, O., Solomon, A. S. & Schwartz, M. Peripheral nerve-stimulated macrophages simulate a peripheral nerve-like regenerative response in rat transected optic nerve. Glia 24, 329-337 (1998). (Pubitemid 28465980)
    • (1998) GLIA , vol.24 , Issue.3 , pp. 329-337
    • Lazarov-Spiegler, O.1    Solomon, A.S.2    Schwartz, M.3
  • 97
    • 0034659957 scopus 로고    scopus 로고
    • Lens injury stimulates axon regeneration in the mature rat optic nerve
    • Leon, S., Yin, Y., Nguyen, J., Irwin, N. & Benowitz, L. I. Lens injury stimulates axon regeneration in the mature rat optic nerve. J. Neurosci. 20, 4615-4626 (2000). (Pubitemid 30396627)
    • (2000) Journal of Neuroscience , vol.20 , Issue.12 , pp. 4615-4626
    • Leon, S.1    Yin, Y.2    Nguyen, J.3    Irwin, N.4    Benowitz, L.I.5
  • 99
    • 33745712928 scopus 로고    scopus 로고
    • Oncomodulin is a macrophage-derived signal for axon regeneration in retinal ganglion cells
    • Yin, Y. et al. Oncomodulin is a macrophage-derived signal for axon regeneration in retinal ganglion cells. Nature Neurosci. 9, 843-852 (2006).
    • (2006) Nature Neurosci. , vol.9 , pp. 843-852
    • Yin, Y.1
  • 100
    • 0031731993 scopus 로고    scopus 로고
    • Interleukin-4 and interferon-γ: The quintessence of a mutual antagonistic relationship
    • DOI 10.1046/j.1365-3083.1998.00435.x
    • Paludan, S. R. Interleukin-4 and interferon-γ: the quintessence of a mutual antagonistic relationship. Scand. J. Immunol. 48, 459-468 (1998). (Pubitemid 28505668)
    • (1998) Scandinavian Journal of Immunology , vol.48 , Issue.5 , pp. 459-468
    • Paludan, S.R.1
  • 103
    • 0037775352 scopus 로고    scopus 로고
    • IL-13 effector functions
    • DOI 10.1146/annurev.immunol.21.120601.141142
    • Wynn, T. A. IL-13 effector functions. Annu. Rev. Immunol. 21, 425-456 (2003). (Pubitemid 37174537)
    • (2003) Annual Review of Immunology , vol.21 , pp. 425-456
    • Wynn, T.A.1
  • 104
    • 3543107212 scopus 로고    scopus 로고
    • Fibrotic disease and the T(H)1/T(H)2 paradigm
    • Wynn, T. A. Fibrotic disease and the T(H)1/T(H)2 paradigm. Nature Rev. Immunol. 4, 583-594 (2004).
    • (2004) Nature Rev. Immunol. , vol.4 , pp. 583-594
    • Wynn, T.A.1
  • 105
    • 28544446111 scopus 로고    scopus 로고
    • Monocyte and macrophage heterogeneity
    • DOI 10.1038/nri1733
    • Gordon, S. & Taylor, P. R. Monocyte and macrophage heterogeneity. Nature Rev. Immunol. 5, 953-964 (2005). (Pubitemid 41746764)
    • (2005) Nature Reviews Immunology , vol.5 , Issue.12 , pp. 953-964
    • Gordon, S.1    Taylor, P.R.2
  • 106
    • 67650485985 scopus 로고    scopus 로고
    • Alternative activation of macrophages: An immunologic functional perspective
    • Martinez, F. O., Helming, L. & Gordon, S. Alternative activation of macrophages: an immunologic functional perspective. Annu. Rev. Immunol. 27, 451-483 (2009).
    • (2009) Annu. Rev. Immunol. , vol.27 , pp. 451-483
    • Martinez, F.O.1    Helming, L.2    Gordon, S.3
  • 107
    • 77956976681 scopus 로고    scopus 로고
    • Macrophage plasticity and interaction with lymphocyte subsets: Cancer as a paradigm
    • Biswas, S. K. & Mantovani, A. Macrophage plasticity and interaction with lymphocyte subsets: cancer as a paradigm. Nature Immunol. 11, 889-896 (2010).
    • (2010) Nature Immunol. , vol.11 , pp. 889-896
    • Biswas, S.K.1    Mantovani, A.2
  • 108
    • 70449491904 scopus 로고    scopus 로고
    • Orchestration of macrophage polarization
    • Mantovani, A. & Locati, M. Orchestration of macrophage polarization. Blood 114, 3135-3136 (2009).
    • (2009) Blood , vol.114 , pp. 3135-3136
    • Mantovani, A.1    Locati, M.2
  • 109
    • 48349102876 scopus 로고    scopus 로고
    • Macrophage polarization in tumour progression
    • Sica, A. et al. Macrophage polarization in tumour progression. Semin. Cancer Biol. 18, 349-355 (2008).
    • (2008) Semin. Cancer Biol. , vol.18 , pp. 349-355
    • Sica, A.1
  • 110
    • 34547428478 scopus 로고    scopus 로고
    • Characterization and modeling of monocyte-derived macrophages after spinal cord injury
    • DOI 10.1111/j.1471-4159.2007.04617.x
    • Longbrake, E. E., Lai, W., Ankeny, D. P. & Popovich, P. G. Characterization and modeling of monocyte-derived macrophages after spinal cord injury. J. Neurochem. 102, 1083-1094 (2007). (Pubitemid 47174229)
    • (2007) Journal of Neurochemistry , vol.102 , Issue.4 , pp. 1083-1094
    • Longbrake, E.E.1    Lai, W.2    Ankeny, D.P.3    Popovich, P.G.4
  • 111
    • 70350558453 scopus 로고    scopus 로고
    • Identification of two distinct macrophage subsets with divergent effects causing either neurotoxicity or regeneration in the injured mouse spinal cord
    • Kigerl, K. A. et al. Identification of two distinct macrophage subsets with divergent effects causing either neurotoxicity or regeneration in the injured mouse spinal cord. J. Neurosci. 29, 13435-13444 (2009).
    • (2009) J. Neurosci. , vol.29 , pp. 13435-13444
    • Kigerl, K.A.1
  • 112
    • 74249092835 scopus 로고    scopus 로고
    • Beneficial effects of secretory leukocyte protease inhibitor after spinal cord injury
    • Ghasemlou, N. et al. Beneficial effects of secretory leukocyte protease inhibitor after spinal cord injury. Brain 133, 126-138 (2010).
    • (2010) Brain , vol.133 , pp. 126-138
    • Ghasemlou, N.1
  • 113
    • 77958052388 scopus 로고    scopus 로고
    • Mitogen-activated protein kinase-activated protein kinase 2 (MK2) contributes to secondary damage after spinal cord injury
    • Ghasemlou, N. et al. Mitogen-activated protein kinase-activated protein kinase 2 (MK2) contributes to secondary damage after spinal cord injury. J. Neurosci. 30, 13750-13759 (2010).
    • (2010) J. Neurosci. , vol.30 , pp. 13750-13759
    • Ghasemlou, N.1
  • 114
    • 38949195067 scopus 로고    scopus 로고
    • 2 in spinal cord injury
    • DOI 10.1002/glia.20630
    • Kerr, B. J., Girolami, E. I., Ghasemlou, N., Jeong, S. Y. & David, S. The protective effects of 15-deoxy-δ-(12, 14)-prostaglandin J2 in spinal cord injury. Glia 56, 436-448 (2008). (Pubitemid 351212952)
    • (2008) GLIA , vol.56 , Issue.4 , pp. 436-448
    • Kerr, B.J.1    Girolami, E.I.2    Ghasemlou, N.3    Suh, Y.J.4    David, S.5
  • 115
    • 77749313475 scopus 로고    scopus 로고
    • Fenretinide promotes functional recovery and tissue protection after spinal cord contusion injury in mice
    • Lopez-Vales, R. et al. Fenretinide promotes functional recovery and tissue protection after spinal cord contusion injury in mice. J. Neurosci. 30, 3220-3226 (2010).
    • (2010) J. Neurosci. , vol.30 , pp. 3220-3226
    • Lopez-Vales, R.1
  • 116
    • 79851487004 scopus 로고    scopus 로고
    • Expression and detrimental role of hematopoietic prostaglandin D synthase in spinal cord contusion injury
    • Redensek, A. et al. Expression and detrimental role of hematopoietic prostaglandin D synthase in spinal cord contusion injury. Glia 59, 603-614 (2011).
    • (2011) Glia , vol.59 , pp. 603-614
    • Redensek, A.1
  • 117
    • 61349166461 scopus 로고    scopus 로고
    • Deletion of macrophage migration inhibitory factor attenuates neuronal death and promotes functional recovery after compression-induced spinal cord injury in mice
    • Nishio, Y. et al. Deletion of macrophage migration inhibitory factor attenuates neuronal death and promotes functional recovery after compression-induced spinal cord injury in mice. Acta Neuropathol. 117, 321-328 (2009).
    • (2009) Acta Neuropathol. , vol.117 , pp. 321-328
    • Nishio, Y.1
  • 118
    • 58249115262 scopus 로고    scopus 로고
    • Increased oxidative activity in human blood neutrophils and monocytes after spinal cord injury
    • Bao, F. et al. Increased oxidative activity in human blood neutrophils and monocytes after spinal cord injury. Exp. Neurol. 215, 308-316 (2009).
    • (2009) Exp. Neurol. , vol.215 , pp. 308-316
    • Bao, F.1
  • 119
    • 1642358379 scopus 로고    scopus 로고
    • Early anti-inflammatory treatment reduces lipid peroxidation and protein nitration after spinal cord injury in rats
    • Bao, F., Chen, Y., Dekaban, G. A. & Weaver, L. C. Early anti-inflammatory treatment reduces lipid peroxidation and protein nitration after spinal cord injury in rats. J. Neurochem. 88, 1335-1344 (2004). (Pubitemid 38366908)
    • (2004) Journal of Neurochemistry , vol.88 , Issue.6 , pp. 1335-1344
    • Bao, F.1    Chen, Y.2    Dekaban, G.A.3    Weaver, L.C.4
  • 120
    • 58149373436 scopus 로고    scopus 로고
    • Ceruloplasmin protects injured spinal cord from iron-mediated oxidative damage
    • Rathore, K. I. et al. Ceruloplasmin protects injured spinal cord from iron-mediated oxidative damage. J. Neurosci. 28, 12736-12747 (2008).
    • (2008) J. Neurosci. , vol.28 , pp. 12736-12747
    • Rathore, K.I.1
  • 121
    • 78650996588 scopus 로고    scopus 로고
    • Altered M1/M2 activation patterns of monocytes in severe relapsing experimental rat model of multiple sclerosis. Amelioration of clinical status by M2 activated monocyte administration
    • Mikita, J. et al. Altered M1/M2 activation patterns of monocytes in severe relapsing experimental rat model of multiple sclerosis. Amelioration of clinical status by M2 activated monocyte administration. Mult. Scler. 17, 2-15 (2011).
    • (2011) Mult. Scler. , vol.17 , pp. 2-15
    • Mikita, J.1
  • 122
    • 78649354194 scopus 로고    scopus 로고
    • Differential expression of SOCS1 in macrophages in relapsing-remitting and chronic EAE and its role in disease severity
    • Berard, J. L., Kerr, B. J., Johnson, H. M. & David, S. Differential expression of SOCS1 in macrophages in relapsing-remitting and chronic EAE and its role in disease severity. Glia 58, 1816-1826 (2010).
    • (2010) Glia , vol.58 , pp. 1816-1826
    • Berard, J.L.1    Kerr, B.J.2    Johnson, H.M.3    David, S.4
  • 123
    • 33750813483 scopus 로고    scopus 로고
    • Transcriptional profiling of the human monocyte-to-macrophage differentiation and polarization: New molecules and patterns of gene expression
    • Martinez, F. O., Gordon, S., Locati, M. & Mantovani, A. Transcriptional profiling of the human monocyte-to-macrophage differentiation and polarization: new molecules and patterns of gene expression. J. Immunol. 177, 7303-7311 (2006). (Pubitemid 44715100)
    • (2006) Journal of Immunology , vol.177 , Issue.10 , pp. 7303-7311
    • Martinez, F.O.1    Gordon, S.2    Locati, M.3    Mantovani, A.4
  • 125
    • 33846886486 scopus 로고    scopus 로고
    • The role of extracellular matrix in CNS regeneration
    • DOI 10.1016/j.conb.2006.09.004, PII S0959438807000025
    • Busch, S. A. & Silver, J. The role of extracellular matrix in CNS regeneration. Curr. Opin. Neurobiol. 17, 120-127 (2007). (Pubitemid 46227979)
    • (2007) Current Opinion in Neurobiology , vol.17 , Issue.1 , pp. 120-127
    • Busch, S.A.1    Silver, J.2
  • 126
    • 33947645277 scopus 로고    scopus 로고
    • The role of chondroitin sulfate proteoglycans in regeneration and plasticity in the central nervous system
    • DOI 10.1016/j.brainresrev.2006.09.006, PII S0165017306001093
    • Galtrey, C. M. & Fawcett, J. W. The role of chondroitin sulfate proteoglycans in regeneration and plasticity in the central nervous system. Brain Res. Rev. 54, 1-18 (2007). (Pubitemid 46498163)
    • (2007) Brain Research Reviews , vol.54 , Issue.1 , pp. 1-18
    • Galtrey, C.M.1    Fawcett, J.W.2
  • 127
    • 0035029305 scopus 로고    scopus 로고
    • Regeneration of CNS axons back to their target following treatment of adult rat brain with chondroitinase ABC
    • Moon, L. D., Asher, R. A., Rhodes, K. E. & Fawcett, J. W. Regeneration of CNS axons back to their target following treatment of adult rat brain with chondroitinase ABC. Nature Neurosci. 4, 465-466 (2001). (Pubitemid 32397182)
    • (2001) Nature Neuroscience , vol.4 , Issue.5 , pp. 465-466
    • Moon, L.D.F.1    Asher, R.A.2    Rhodes, K.E.3    Fawcett, J.W.4
  • 128
    • 68849086666 scopus 로고    scopus 로고
    • Overcoming macrophage-mediated axonal dieback following CNS injury
    • Busch, S. A., Horn, K. P., Silver, D. J. & Silver, J. Overcoming macrophage-mediated axonal dieback following CNS injury. J. Neurosci. 29, 9967-9976 (2009).
    • (2009) J. Neurosci. , vol.29 , pp. 9967-9976
    • Busch, S.A.1    Horn, K.P.2    Silver, D.J.3    Silver, J.4
  • 129
    • 56949089831 scopus 로고    scopus 로고
    • Another barrier to regeneration in the CNS: Activated macrophages induce extensive retraction of dystrophic axons through direct physical interactions
    • Horn, K. P., Busch, S. A., Hawthorne, A. L., van Rooijen, N. & Silver, J. Another barrier to regeneration in the CNS: activated macrophages induce extensive retraction of dystrophic axons through direct physical interactions. J. Neurosci. 28, 9330-9341 (2008).
    • (2008) J. Neurosci. , vol.28 , pp. 9330-9341
    • Horn, K.P.1    Busch, S.A.2    Hawthorne, A.L.3    Van Rooijen, N.4    Silver, J.5
  • 130
    • 33645740851 scopus 로고    scopus 로고
    • RGMa inhibition promotes axonal growth and recovery after spinal cord injury
    • Hata, K. et al. RGMa inhibition promotes axonal growth and recovery after spinal cord injury. J. Cell Biol. 173, 47-58 (2006).
    • (2006) J. Cell Biol. , vol.173 , pp. 47-58
    • Hata, K.1
  • 133
    • 38349091128 scopus 로고    scopus 로고
    • Myelin-phagocytosing macrophages in isolated sciatic and optic nerves reveal a unique reactive phenotype
    • van Rossum, D., Hilbert, S., Strassenburg, S., Hanisch, U. K. & Bruck, W. Myelin-phagocytosing macrophages in isolated sciatic and optic nerves reveal a unique reactive phenotype. Glia 56, 271-283 (2008).
    • (2008) Glia , vol.56 , pp. 271-283
    • Van Rossum, D.1    Hilbert, S.2    Strassenburg, S.3    Hanisch, U.K.4    Bruck, W.5
  • 134
    • 35148835215 scopus 로고    scopus 로고
    • CNS-derived interleukin-4 is essential for the regulation of autoimmune inflammation and induces a state of alternative activation in microglial cells
    • DOI 10.1523/JNEUROSCI.1922-07.2007
    • Ponomarev, E. D., Maresz, K., Tan, Y. & Dittel, B. N. CNS-derived interleukin-4 is essential for the regulation of autoimmune inflammation and induces a state of alternative activation in microglial cells. J. Neurosci. 27, 10714-10721 (2007). (Pubitemid 47535871)
    • (2007) Journal of Neuroscience , vol.27 , Issue.40 , pp. 10714-10721
    • Ponomarev, E.D.1    Maresz, K.2    Tan, Y.3    Dittel, B.N.4
  • 135
    • 77956618333 scopus 로고    scopus 로고
    • Alternatively activated alveolar macrophages in pulmonary fibrosis-mediator production and intracellular signal transduction
    • Pechkovsky, D. V. et al. Alternatively activated alveolar macrophages in pulmonary fibrosis-mediator production and intracellular signal transduction. Clin. Immunol. 137, 89-101 (2010).
    • (2010) Clin. Immunol. , vol.137 , pp. 89-101
    • Pechkovsky, D.V.1
  • 137
    • 79951604413 scopus 로고    scopus 로고
    • Identification of alternatively activated macrophages in new-onset paediatric and adult immunoglobulin A nephropathy: Potential role in mesangial matrix expansion
    • Ikezumi, Y. et al. Identification of alternatively activated macrophages in new-onset paediatric and adult immunoglobulin A nephropathy: potential role in mesangial matrix expansion. Histopathology 58, 198-210 (2011).
    • (2011) Histopathology , vol.58 , pp. 198-210
    • Ikezumi, Y.1
  • 138
    • 79959374455 scopus 로고    scopus 로고
    • Alternative activation of macrophages in human peritoneum: Implications for peritoneal fibrosis
    • 15 Feb doi:10.1093/ndt/gfq771
    • Bellon, T. et al. Alternative activation of macrophages in human peritoneum: implications for peritoneal fibrosis. Nephrol. Dial. Transplant 15 Feb 2011 (doi:10.1093/ndt/gfq771).
    • (2011) Nephrol. Dial. Transplant
    • Bellon, T.1
  • 139
    • 0036839143 scopus 로고    scopus 로고
    • Macrophage polarization: Tumor-associated macrophages as a paradigm for polarized M2 mononuclear phagocytes
    • DOI 10.1016/S1471-4906(02)02302-5, PII S1471490602023025
    • Mantovani, A., Sozzani, S., Locati, M., Allavena, P. & Sica, A. Macrophage polarization: tumor-associated macrophages as a paradigm for polarized M2 mononuclear phagocytes. Trends Immunol. 23, 549-555 (2002). (Pubitemid 35223554)
    • (2002) Trends in Immunology , vol.23 , Issue.11 , pp. 549-555
    • Mantovani, A.1    Sozzani, S.2    Locati, M.3    Allavena, P.4    Sica, A.5
  • 140
    • 45549109370 scopus 로고    scopus 로고
    • Activation of a TGF-β-specific multistep gene expression program in mature macrophages requires glucocorticoid-mediated surface expression of TGF-β receptor II
    • Gratchev, A. et al. Activation of a TGF-β-specific multistep gene expression program in mature macrophages requires glucocorticoid-mediated surface expression of TGF-β receptor II. J. Immunol. 180, 6553-6565 (2008).
    • (2008) J. Immunol. , vol.180 , pp. 6553-6565
    • Gratchev, A.1
  • 141
    • 33748102856 scopus 로고    scopus 로고
    • Hepcidin - A peptide hormone at the interface of innate immunity and iron metabolism
    • Antimicrobial Peptides and Human Disease
    • Ganz, T. Hepcidin-a peptide hormone at the interface of innate immunity and iron metabolism. Curr. Top. Microbiol. Immunol. 306, 183-198 (2006). (Pubitemid 47400322)
    • (2006) Current Topics in Microbiology and Immunology , vol.306 , pp. 183-198
    • Ganz, T.1
  • 142
  • 143
    • 79952135247 scopus 로고    scopus 로고
    • An unrestrained proinflammatory M1 macrophage population induced by iron impairs wound healing in humans and mice
    • Sindrilaru, A. et al. An unrestrained proinflammatory M1 macrophage population induced by iron impairs wound healing in humans and mice. J. Clin. Invest. 121, 985-997 (2011).
    • (2011) J. Clin. Invest. , vol.121 , pp. 985-997
    • Sindrilaru, A.1
  • 144
    • 78650742405 scopus 로고    scopus 로고
    • The interaction of human natural killer cells with either unpolarized or polarized macrophages results in different functional outcomes
    • Bellora, F. et al. The interaction of human natural killer cells with either unpolarized or polarized macrophages results in different functional outcomes. Proc. Natl Acad. Sci. USA 107, 21659-21664 (2010).
    • (2010) Proc. Natl Acad. Sci. USA , vol.107 , pp. 21659-21664
    • Bellora, F.1
  • 146
    • 0030250093 scopus 로고    scopus 로고
    • + subpopulation
    • DOI 10.1016/0167-5699(96)10029-3
    • Ziegler-Heitbrock, H. W. Heterogeneity of human blood monocytes: the CD14+ CD16+ subpopulation. Immunol. Today 17, 424-428 (1996). (Pubitemid 26278368)
    • (1996) Immunology Today , vol.17 , Issue.9 , pp. 424-428
    • Ziegler-Heitbrock, H.W.L.1
  • 148
    • 7644231561 scopus 로고    scopus 로고
    • The chemokine system in diverse forms of macrophage activation and polarization
    • DOI 10.1016/j.it.2004.09.015, PII S1471490604002959
    • Mantovani, A. et al. The chemokine system in diverse forms of macrophage activation and polarization. Trends Immunol. 25, 677-686 (2004). (Pubitemid 39457982)
    • (2004) Trends in Immunology , vol.25 , Issue.12 , pp. 677-686
    • Mantovani, A.1    Sica, A.2    Sozzani, S.3    Allavena, P.4    Vecchi, A.5    Locati, M.6
  • 150
    • 0026762988 scopus 로고
    • Interleukin 4 potently enhances murine macrophage mannose receptor activity: A marker of alternative immunologic macrophage activation
    • Stein, M., Keshav, S., Harris, N. & Gordon, S. Interleukin 4 potently enhances murine macrophage mannose receptor activity: a marker of alternative immunologic macrophage activation. J. Exp. Med. 176, 287-292 (1992).
    • (1992) J. Exp. Med. , vol.176 , pp. 287-292
    • Stein, M.1    Keshav, S.2    Harris, N.3    Gordon, S.4
  • 151
  • 152
    • 0035576207 scopus 로고    scopus 로고
    • Differential regulation of nitric oxide synthase-2 and arginase-1 by type 1/type 2 cytokines in vivo: Granulomatous pathology is shaped by the pattern of L-arginine metabolism
    • Hesse, M. et al. Differential regulation of nitric oxide synthase-2 and arginase-1 by type 1/type 2 cytokines in vivo: granulomatous pathology is shaped by the pattern of L-arginine metabolism. J. Immunol. 167, 6533-6544 (2001). (Pubitemid 33081589)
    • (2001) Journal of Immunology , vol.167 , Issue.11 , pp. 6533-6544
    • Hesse, M.1    Modolell, M.2    La Flamme, A.C.3    Schito, M.4    Fuentes, J.M.5    Cheever, A.W.6    Pearce, E.J.7    Wynn, T.A.8
  • 153
    • 0037265240 scopus 로고    scopus 로고
    • Alternative activation of macrophages
    • DOI 10.1038/nri978
    • Gordon, S. Alternative activation of macrophages. Nature Rev. Immunol. 3, 23-35 (2003). (Pubitemid 37328697)
    • (2003) Nature Reviews Immunology , vol.3 , Issue.1 , pp. 23-35
    • Gordon, S.1
  • 154
    • 73649131506 scopus 로고    scopus 로고
    • Arginase-1 and Ym1 are markers for murine, but not human, alternatively activated myeloid cells
    • author reply 6561-6562
    • Raes, G. et al. Arginase-1 and Ym1 are markers for murine, but not human, alternatively activated myeloid cells. J. Immunol. 174, 6561; author reply 6561-6562 (2005).
    • (2005) J. Immunol. , vol.174 , pp. 6561
    • Raes, G.1
  • 156
    • 58749098598 scopus 로고    scopus 로고
    • Shifts in macrophage phenotypes and macrophage competition for arginine metabolism affect the severity of muscle pathology in muscular dystrophy
    • Villalta, S. A., Nguyen, H. X., Deng, B., Gotoh, T. & Tidball, J. G. Shifts in macrophage phenotypes and macrophage competition for arginine metabolism affect the severity of muscle pathology in muscular dystrophy. Hum. Mol. Genet. 18, 482-496 (2009).
    • (2009) Hum. Mol. Genet. , vol.18 , pp. 482-496
    • Villalta, S.A.1    Nguyen, H.X.2    Deng, B.3    Gotoh, T.4    Tidball, J.G.5
  • 157
    • 0033082935 scopus 로고    scopus 로고
    • Other functions, other genes: Alternative activation of antigen- presenting cells
    • Goerdt, S. & Orfanos, C. E. Other functions, other genes: alternative activation of antigen-presenting cells. Immunity 10, 137-142 (1999). (Pubitemid 29115619)
    • (1999) Immunity , vol.10 , Issue.2 , pp. 137-142
    • Goerdt, S.1    Orfanos, C.E.2
  • 158
    • 0037090186 scopus 로고    scopus 로고
    • Cutting edge: Biasing immune responses by directing antigen to macrophage Fcγ receptors
    • Anderson, C. F. & Mosser, D. M. Cutting edge: biasing immune responses by directing antigen to macrophage Fc γ receptors. J. Immunol. 168, 3697-3701 (2002). (Pubitemid 34298366)
    • (2002) Journal of Immunology , vol.168 , Issue.8 , pp. 3697-3701
    • Anderson, C.F.1    Mosser, D.M.2
  • 159
    • 0036658739 scopus 로고    scopus 로고
    • A novel phenotype for an activated macrophage: The type 2 activated macrophage
    • Anderson, C. F. & Mosser, D. M. A novel phenotype for an activated macrophage: the type 2 activated macrophage. J. Leukoc. Biol. 72, 101-106 (2002).
    • (2002) J. Leukoc. Biol. , vol.72 , pp. 101-106
    • Anderson, C.F.1    Mosser, D.M.2
  • 160
    • 0037310024 scopus 로고    scopus 로고
    • The many faces of macrophage activation
    • DOI 10.1189/jlb.0602325
    • Mosser, D. M. The many faces of macrophage activation. J. Leukoc. Biol. 73, 209-212 (2003). (Pubitemid 36158295)
    • (2003) Journal of Leukocyte Biology , vol.73 , Issue.2 , pp. 209-212
    • Mosser, D.M.1
  • 161
    • 77956919603 scopus 로고    scopus 로고
    • Proinflammatory clearance of apoptotic neutrophils induces an IL-12lowIL-10high regulatory phenotype in macrophages
    • Filardy, A. A. et al. Proinflammatory clearance of apoptotic neutrophils induces an IL-12lowIL-10high regulatory phenotype in macrophages. J. Immunol. 185, 2044-2050 (2010).
    • (2010) J. Immunol. , vol.185 , pp. 2044-2050
    • Filardy, A.A.1
  • 162
    • 78650603732 scopus 로고    scopus 로고
    • Activation of lung macrophage subpopulations in experimental acute pancreatitis
    • Gea-Sorli, S., Guillamat, R., Serrano-Mollar, A. & Closa, D. Activation of lung macrophage subpopulations in experimental acute pancreatitis. J. Pathol. 223, 417-424 (2011).
    • (2011) J. Pathol. , vol.223 , pp. 417-424
    • Gea-Sorli, S.1    Guillamat, R.2    Serrano-Mollar, A.3    Closa, D.4
  • 163
    • 0026457998 scopus 로고
    • Contrasting mechanisms for suppression of macrophage cytokine release by transforming growth factor-β and interleukin-10
    • Bogdan, C., Paik, J., Vodovotz, Y. & Nathan, C. Contrasting mechanisms for suppression of macrophage cytokine release by transforming growth factor-β and interleukin-10. J. Biol. Chem. 267, 23301-23308 (1992).
    • (1992) J. Biol. Chem. , vol.267 , pp. 23301-23308
    • Bogdan, C.1    Paik, J.2    Vodovotz, Y.3    Nathan, C.4
  • 164
    • 1642457242 scopus 로고    scopus 로고
    • Nuclear receptor signaling in macrophages
    • DOI 10.1016/j.bcp.2003.10.016
    • Valledor, A. F. & Ricote, M. Nuclear receptor signaling in macrophages. Biochem. Pharmacol. 67, 201-212 (2004). (Pubitemid 38112751)
    • (2004) Biochemical Pharmacology , vol.67 , Issue.2 , pp. 201-212
    • Valledor, A.F.1    Ricote, M.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.