Molecular cloning and regional distribution of a human proton receptor subunit with biphasic functional properties

Journal of Neurochemistry

Volumn 72, Issue 1, 1999, Pages 51-57

  Babinski, Kazimierz ^a   Lê, Khanh Tuoc ^a   Séguéla, Philippe ^a  

^a MCGILL UNIVERSITY   (Canada)

Author keywords

Amiloride; Degenerin; Pain; Proton gated channel; Trigeminal sensory neurons; Xenopus oocytes

Indexed keywords

ANIMAL CELL; ARTICLE; CAENORHABDITIS ELEGANS; CHANNEL GATING; CHEMOSENSITIVITY; MOLECULAR CLONING; NOCICEPTION; NONHUMAN; PH MEASUREMENT; PRIORITY JOURNAL; PROTON TRANSPORT; TRIGEMINAL NERVE; XENOPUS;

AMILORIDE; AMINO ACID SEQUENCE; ANIMALS; BASE SEQUENCE; CLONING, MOLECULAR; DIURETICS; ELECTRIC STIMULATION; ELECTROPHYSIOLOGY; GENE EXPRESSION; HYDROGEN-ION CONCENTRATION; ION CHANNEL GATING; MEMBRANE POTENTIALS; MEMBRANE PROTEINS; MOLECULAR SEQUENCE DATA; NERVE TISSUE PROTEINS; NEURONS, AFFERENT; OOCYTES; PROTONS; SODIUM CHANNELS; TRIGEMINAL NUCLEI; XENOPUS LAEVIS;

ANIMALIA; CAENORHABDITIS ELEGANS; MAMMALIA;

EID: 0032900533     PISSN: 00223042     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1471-4159.1999.0720051.x     Document Type: Article

References (29)

1. Adams C. M., Anderson M. G., Motto D. G., Price M. P., Johnson W. A., and Welsh M. J. (1998) Ripped pocket and pickpocket, novel Drosophila DEG/ENaC subunits expressed in early development and in mechanosensory neurons. J. Cell Biol. 140, 143-152.
2. + channel with novel properties. J. Biol. Chem. 272, 28819-28822.
3. Bertrand D., Cooper E., Valera S., Rungger D., and Ballivet M. (1991) Electrophysiology of neuronal nicotinic acetylcholine receptors expressed in Xenopus oocytes following nuclear injection of genes or cDNAs, in Methods in Neurosciences (Conn M. P., ed), pp. 174-193. Academic Press, San Diego.
4. Bevan S. and Winter J. (1995) Nerve growth factor (NGF) differentially regulates the chemosensitivity of adult rat cultured sensory neurons. J. Neurosci. 15, 4918-4926.
5. Bevan S. and Yeats J. (1991) Protons activate a cation conductance in a subpopulation of rat dorsal root ganglion neurones. J. Physiol. (Lond.) 433, 145-161.
6. Canessa C. M., Merillat A. M., and Rossier B. C. (1994a) Membrane topology of the epithelial sodium channel in intact cells. Am. J. Physiol 267, C1682-C1690.
7. + channel is made of three homologous subunits. Nature 367, 463-467.
8. Corey D. P. and Garcia-Anoveros J. (1996) Mechanosensation and the DEG/ENaC ion channels. Science 273, 323-324.
9. Coscoy S., Lingueglia E., Lazdunski M., and Barbry P. (1998) The Phe-Met-Arg-Phe-amide-activated sodium channel is a tetramer. J. Biol. Chem. 273, 8317-8322.
10. De Léan A., Munson P. J., and Rodbard D. (1978) Simultaneous analysis of families of sigmoidal curves: application to bioassay. radioligand assay, and physiological dose-response curves. Am. J. Physiol. 235, E97-E102.
11. Dray A. and Perkins M. (1993) Bradykinin and inflammatory pain. Trends Neurosci. 16, 99-104.
12. Firsov D., Gautschi I., Merillat A.-M., Rossier B. C., and Schild L. (1998) The heterotetrameric architecture of the epithelial sodium channel (ENaC). EMBO J. 17, 344-352.
13. Garcia-Anoveros J., Derfler B., Neville-Golden J., Hyman B. T., and Corey D. P. (1997) BNaC1 and BNaC2 constitute a new family of human neuronal sodium channels related to degenerins and epithelial sodium channels. Proc. Natl. Acad. Sci. USA 94, 1459-1464.
14. Ishibashi K. and Marumo F. (1998) Molecular cloning of a DEG/ENaC sodium channel from human testis. Biochem. Biophys. Res. Commun. 245, 589-593.
15. Kleyman T. R. and Cragoe E. J. (1988) Amiloride and its analogs as tools in the study of ion transport. J. Membr. Biol. 105, 1-21.
16. Konnerth A., Lux H. D., and Morad M. (1987) Proton-induced transformation of calcium channel in chick dorsal root ganglion cells. J. Physiol. (Lond.) 386, 603-633.
17. Krishtal O. A. and Pidoplichko V. I. (1981) A receptor for protons in the membrane of sensory neurons may participate in nociception. Neuroscience 6, 2599-2601.
18. Krishtal O. A., Osipchuk Y. V., Shelest T. N., and Smirnoff S. V. (1987) Rapid extracellular pH transients related to synaptic transmission in rat hippocampal slices. Brain Res. 436, 352-356.
19. Lennon G., Auffray C., Polymeropoulos M., and Soares M. B. (1996) The I.M.A.G.E. consortium; an integrated molecular analysis of genomes and their expression. Genomics 33, 151-152.
20. Lindahl O. (1974) Pain - a general chemical explanation. Adv. Neurol. 4, 45-47.
21. Lingueglia E., Champigny G., Lazdunski M., and Barbry P. (1995) Cloning of the amiloride-sensitive FMRFamide peptide-gated sodium channel. Nature 378, 730-733.
22. Lingueglia E., de Weille J. R., Bassilana F., Heurteaux C., Sakai H., Waldmann R., and Lazdunski M. (1997) A modulatory subunit of acid sensing ion channels in brain and dorsal root ganglion cells. J. Biol. Chem. 272, 29778-29783.
23. North R. A. (1997) Families of ion channels with two hydrophobic segments. Curr. Opin. Cell Biol. 8, 474-483.
24. + channel. J. Biol. Chem. 271, 7879-7882.
25. Snyder P. M., Cheng C., Prince L. S., Rogers J. C., and Welsh M. J. (1998) Electrophysiological and biochemical evidence that DEG/ ENaC cation channels are composed of nine subunits. J. Biol. Chem. 273, 681-684.
26. Tavernarakis N., Shreffler W., Wang S., and Driscoll M. (1997) unc-8, a DEG/ENaC family member, encodes a subunit of a candidate mechanically gated channel that modulates C. elegans locomotion. Neuron 18, 107-119.
27. Waldmann R., Champigny G., Voilley N., Lauritzen I., and Lazdunski M. (1996) The mammalian degenerin MDEG. an amiloride-sensitive cation channel activated by mutations causing neurodegeneration in Caenorhabditis elegans. J. Biol. Chem. 271, 10433-10436.
28. + channel specific for sensory neurons. J. Biol. Chem. 272, 20975-20978.
29. Waldmann R., Champigny G., Bassilana F., Heurteaux C., and Lazdunski M. (1997b) A proton-gated cation channel involved in acid-sensing. Nature 386, 173-177.