메뉴 건너뛰기




Volumn 85, Issue 9, 1999, Pages 777-786

The myocardial Na+-H+ exchange: Structure, regulation, and its role in heart disease

Author keywords

Heart failure; Hypertrophy; Ischemia reperfusion; Na+ H+ exchange; Remodeling

Indexed keywords

ADENOSINE TRIPHOSPHATASE (POTASSIUM SODIUM); CALCIUM; ENIPORIDE; SODIUM; SODIUM CHANNEL BLOCKING AGENT; UNCLASSIFIED DRUG;

EID: 0032749318     PISSN: 00097330     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.RES.85.9.777     Document Type: Review
Times cited : (365)

References (126)
  • 1
    • 0033563037 scopus 로고    scopus 로고
    • Characterization of intracellular pH in the guinea-pig ventricular myocyte
    • Leem CH, Lagadic-Gossmann D, Vaughan-Jones RD. Characterization of intracellular pH in the guinea-pig ventricular myocyte. J Physiol. 1999;517:159-180.
    • (1999) J Physiol. , vol.517 , pp. 159-180
    • Leem, C.H.1    Lagadic-Gossmann, D.2    Vaughan-Jones, R.D.3
  • 3
    • 0027432420 scopus 로고
    • + exchanger: An update on structure, regulation and cardiac physiology
    • + exchanger: an update on structure, regulation and cardiac physiology. Biochem J. 1993;296:273-285.
    • (1993) Biochem J. , vol.296 , pp. 273-285
    • Fliegel, L.1    Fröhlich, O.2
  • 6
    • 0032516911 scopus 로고    scopus 로고
    • + exchanger in a late endosomal compartment of yeast: Implications for vacuole biogenesis
    • + exchanger in a late endosomal compartment of yeast: implications for vacuole biogenesis. J Biol Chem. 1998;273:21054-21060.
    • (1998) J Biol Chem. , vol.273 , pp. 21054-21060
    • Nass, R.1    Rao, R.2
  • 7
    • 0026806528 scopus 로고
    • Molecular cloning of putative members of the Na/H exchanger gene family
    • Orlowski J, Kandasamy RA, Shull GE. Molecular cloning of putative members of the Na/H exchanger gene family. J Biol Chem. 1992;267: 9331-9339.
    • (1992) J Biol Chem. , vol.267 , pp. 9331-9339
    • Orlowski, J.1    Kandasamy, R.A.2    Shull, G.E.3
  • 9
    • 0028835681 scopus 로고
    • Structure-function studies and molecular regulation of the growth factor activatable sodium-hydrogen exchanger (NHE-1)
    • Counillon L, Pouysségur J. Structure-function studies and molecular regulation of the growth factor activatable sodium-hydrogen exchanger (NHE-1). Cardiovasc Res. 1995;29:147-154.
    • (1995) Cardiovasc Res. , vol.29 , pp. 147-154
    • Counillon, L.1    Pouysségur, J.2
  • 10
    • 0028880396 scopus 로고
    • + exchanger isoforms (NHE-1, -2, and -3) are differentially responsive to second messenger agonists of the protein kinase A and C pathways
    • + exchanger isoforms (NHE-1, -2, and -3) are differentially responsive to second messenger agonists of the protein kinase A and C pathways. J Biol Chem. 1995;270:29209-29216.
    • (1995) J Biol Chem. , vol.270 , pp. 29209-29216
    • Kandasamy, R.A.1    Yu, F.H.2    Harris, R.3    Boucher, A.4    Hanrahan, J.W.5    Orlowski, J.6
  • 13
    • 0031127371 scopus 로고    scopus 로고
    • + ions on Na-H exchange in sheep cardiac Purkinje fibers
    • + ions on Na-H exchange in sheep cardiac Purkinje fibers. J Mol Cell Cardiol. 1997;29:1131-1140.
    • (1997) J Mol Cell Cardiol. , vol.29 , pp. 1131-1140
    • Wu, M.L.1    Vaughan-Jones, R.D.2
  • 14
    • 0027062761 scopus 로고
    • Role of bicarbonate in pH recovery from intracellular acidosis in the guinea-pig ventricle myocyte
    • Lagadic-Gossman D, Buckler KJ, Vaughan-Jones RD. Role of bicarbonate in pH recovery from intracellular acidosis in the guinea-pig ventricle myocyte. J Physiol. 1992;458:361-384.
    • (1992) J Physiol. , vol.458 , pp. 361-384
    • Lagadic-Gossman, D.1    Buckler, K.J.2    Vaughan-Jones, R.D.3
  • 15
    • 84878715305 scopus 로고    scopus 로고
    • Austin, Tex: RG Landes Company
    • + Exchanger. Austin, Tex: RG Landes Company; 1996.
    • (1996) + Exchanger
    • Fliegel, L.1
  • 16
    • 0029991882 scopus 로고    scopus 로고
    • + exchanger isoform NHE1: Role of phosphorylation
    • + exchanger isoform NHE1: role of phosphorylation. Kidney Int. 1996;49:1038-1041.
    • (1996) Kidney Int. , vol.49 , pp. 1038-1041
    • Bianchini, L.1    Pouysségur, J.2
  • 19
    • 0028244810 scopus 로고
    • Role of sodium/hydrogen exchange in mediating the effects of endothelin-1 on the normal and ischemic and reperfused heart
    • Khandoudi N, Ho J, Karmazyn M. Role of sodium/hydrogen exchange in mediating the effects of endothelin-1 on the normal and ischemic and reperfused heart. Circ Res. 1994;75:369-378.
    • (1994) Circ Res. , vol.75 , pp. 369-378
    • Khandoudi, N.1    Ho, J.2    Karmazyn, M.3
  • 20
    • 0027490036 scopus 로고
    • + exchange in dog cardiac Purkinje fibers
    • + exchange in dog cardiac Purkinje fibers. J Physiol. 1993;471:583-597.
    • (1993) J Physiol. , vol.471 , pp. 583-597
    • Wu, M.L.1    Tseng, Y.Z.2
  • 22
    • 0033105509 scopus 로고    scopus 로고
    • 2+ signaling in guinea pig ventricular myocytes: Role of protein kinase C
    • 2+ signaling in guinea pig ventricular myocytes: role of protein kinase C. J Mol Cell Cardiol. 1999;31:631-643.
    • (1999) J Mol Cell Cardiol. , vol.31 , pp. 631-643
    • Woo, S.H.1    Lee, C.O.2
  • 23
    • 0028814963 scopus 로고
    • Angiotensin II stimulates sodium-hydrogen exchange in adult rabbit ventricular myocytes
    • Matsui H, Barry WH, Livsey C, Spitzer KW. Angiotensin II stimulates sodium-hydrogen exchange in adult rabbit ventricular myocytes. Cardiovasc Res. 1995;29:215-221.
    • (1995) Cardiovasc Res. , vol.29 , pp. 215-221
    • Matsui, H.1    Barry, W.H.2    Livsey, C.3    Spitzer, K.W.4
  • 24
    • 0031837539 scopus 로고    scopus 로고
    • Effects of angiotensin II on intracellular calcium and contracture in metabolically inhibited cardiomyocytes
    • Boston DR, Koyama T, Rodriguez-Larrain J, Zou A, Su Z, Barry WH. Effects of angiotensin II on intracellular calcium and contracture in metabolically inhibited cardiomyocytes. J Pharmacol Exp Ther. 1998; 285:716-723.
    • (1998) J Pharmacol Exp Ther. , vol.285 , pp. 716-723
    • Boston, D.R.1    Koyama, T.2    Rodriguez-Larrain, J.3    Zou, A.4    Su, Z.5    Barry, W.H.6
  • 26
    • 0026464479 scopus 로고
    • 1-Adrenergic stimulation of the Na-H exchange in cardiac myocytes
    • 1-Adrenergic stimulation of the Na-H exchange in cardiac myocytes. Am J Physiol. 1992;263:C1096-C1102.
    • (1992) Am J Physiol. , vol.263
    • Wallert, M.A.1    Fröhlich, O.2
  • 27
    • 0028797128 scopus 로고
    • Neurohumoral modulation of intracellular pH in the heart
    • Puçéat M, Vassort G. Neurohumoral modulation of intracellular pH in the heart. Cardiovasc Res. 1995;29:178-183.
    • (1995) Cardiovasc Res. , vol.29 , pp. 178-183
    • Puçéat, M.1    Vassort, G.2
  • 29
    • 0029797233 scopus 로고    scopus 로고
    • + exchanger: Evidence for a receptor-mediated mechanism involving protein kinase C
    • + exchanger: evidence for a receptor-mediated mechanism involving protein kinase C. Circ Res. 1996;79:705-715.
    • (1996) Circ Res. , vol.79 , pp. 705-715
    • Yasutake, M.1    Haworth, R.S.2    King, A.3    Avkiran, M.4
  • 32
    • 0343907855 scopus 로고    scopus 로고
    • + exchange inhibition protects against mechanical, ultrastructural, and biochemical impairment induced by low concentrations of lysophosphatidylcholine in isolated rat hearts
    • + exchange inhibition protects against mechanical, ultrastructural, and biochemical impairment induced by low concentrations of lysophosphatidylcholine in isolated rat hearts. Circ Res. 1997;80:95-102.
    • (1997) Circ Res. , vol.80 , pp. 95-102
    • Hoque, A.N.E.1    Haist, J.V.2    Karmazyn, M.3
  • 35
    • 0033551771 scopus 로고    scopus 로고
    • + exchanger in the rat myocardium by mitogen-activated protein kinase-dependent pathways
    • + exchanger in the rat myocardium by mitogen-activated protein kinase-dependent pathways. J Biol Chem. 1999;274:22985-22992.
    • (1999) J Biol Chem. , vol.274 , pp. 22985-22992
    • Moor, A.N.1    Fliegel, L.2
  • 36
    • 0030044744 scopus 로고    scopus 로고
    • Hypoxia and hypoxia/reoxygenation activate Raf-1, mitogen-activated protein kinase kinase, mitogen-activated protein kinases, and S6 kinase in cultured rat cardiac myocytes
    • Seko Y, Tobe K, Ueki K, Kadowaki T, Yazaki Y. Hypoxia and hypoxia/reoxygenation activate Raf-1, mitogen-activated protein kinase kinase, mitogen-activated protein kinases, and S6 kinase in cultured rat cardiac myocytes. Circ Res. 1996;78:82-90.
    • (1996) Circ Res. , vol.78 , pp. 82-90
    • Seko, Y.1    Tobe, K.2    Ueki, K.3    Kadowaki, T.4    Yazaki, Y.5
  • 38
    • 0028242352 scopus 로고
    • + exchanger isoform 1 (NHE1) is a novel member of the calmodulin-binding proteins: Identification and characterization of calmodulin-binding sites
    • + exchanger isoform 1 (NHE1) is a novel member of the calmodulin-binding proteins: identification and characterization of calmodulin-binding sites. J Biol Chem. 1994;269:13703-13709.
    • (1994) J Biol Chem. , vol.269 , pp. 13703-13709
    • Bertrand, B.1    Wakabayashi, S.2    Ikeda, T.3    Pouysségur, J.4    Shigekawa, M.5
  • 40
    • 0001682607 scopus 로고
    • + exchange in the sheep cardiac Purkinje fibre
    • + exchange in the sheep cardiac Purkinje fibre. J Physiol. 1994;471:583-597.
    • (1994) J Physiol. , vol.471 , pp. 583-597
    • Wu, M.1    Vaughan-Jones, R.D.2
  • 46
    • 0000201075 scopus 로고    scopus 로고
    • + exchange through distinct cdc41-dependent and RhoA-dependent pathways
    • + exchange through distinct cdc41-dependent and RhoA-dependent pathways. J Biol Chem. 1996;271:6152-6158.
    • (1996) J Biol Chem. , vol.271 , pp. 6152-6158
    • Hooley, R.1    Yu, C.2    Symons, M.3    Barber, D.L.4
  • 48
    • 0028855712 scopus 로고
    • + exchanger gene by the transcription factor AP-2
    • + exchanger gene by the transcription factor AP-2. J Biol Chem. 1995;270: 1375-1381.
    • (1995) J Biol Chem. , vol.270 , pp. 1375-1381
    • Dyck, J.R.B.1    Nlcl, S.2    Fliegel, L.3
  • 49
    • 0030060047 scopus 로고    scopus 로고
    • Regulation of the NHE-1 promoter in mammalian myocardium
    • Yang W, Dyck JRB, Wang H, Fliegel L. Regulation of the NHE-1 promoter in mammalian myocardium. Am J Physiol. 1996;270: H259-H266.
    • (1996) Am J Physiol. , vol.270
    • Yang, W.1    Dyck, J.R.B.2    Wang, H.3    Fliegel, L.4
  • 50
    • 0029833711 scopus 로고    scopus 로고
    • + exchanger gene expression: Role of a novel poly(dA · dT) element in regulation of the NHE1 promoter
    • + exchanger gene expression: Role of a novel poly(dA · dT) element in regulation of the NHE1 promoter. J Biol Chem. 1996;271:20444-20449.
    • (1996) J Biol Chem. , vol.271 , pp. 20444-20449
    • Yang, W.1    Wang, H.2    Fliegel, L.3
  • 51
    • 0028859824 scopus 로고
    • Induction of expression of the sodium-hydrogen exchanger in rat myocardium
    • Dyck JR, Maddaford TG, Pierce GN, Fliegel L. Induction of expression of the sodium-hydrogen exchanger in rat myocardium. Cardiovasc Res. 1995;29:203-208.
    • (1995) Cardiovasc Res. , vol.29 , pp. 203-208
    • Dyck, J.R.1    Maddaford, T.G.2    Pierce, G.N.3    Fliegel, L.4
  • 53
  • 54
    • 0021251312 scopus 로고
    • + concentration: A molecular basis for the antagonistic effect of ouabain and amiloride on the heart
    • + concentration: a molecular basis for the antagonistic effect of ouabain and amiloride on the heart. J Biol Chem. 1984;259:8880-8885.
    • (1984) J Biol Chem. , vol.259 , pp. 8880-8885
    • Frelin, C.1    Vigne, P.2    Lazdunski, M.3
  • 55
    • 0022461386 scopus 로고
    • Effects of amiloride and ouabain on contractile state, Ca and Na fluxes, and Na content in cultured chick heart cells
    • Kim D, Smith TW. Effects of amiloride and ouabain on contractile state, Ca and Na fluxes, and Na content in cultured chick heart cells. Mol Pharmacol. 1986;29:363-371.
    • (1986) Mol Pharmacol. , vol.29 , pp. 363-371
    • Kim, D.1    Smith, T.W.2
  • 56
    • 0022547613 scopus 로고
    • Selective inhibition by ethylisopropylamiloride of the positive inotropic effect evoked by low concentrations of ouabain in rat isolated ventricles
    • Finet M, Godfraind T. Selective inhibition by ethylisopropylamiloride of the positive inotropic effect evoked by low concentrations of ouabain in rat isolated ventricles. Br J Pharmacol. 1986;89:533-538.
    • (1986) Br J Pharmacol. , vol.89 , pp. 533-538
    • Finet, M.1    Godfraind, T.2
  • 57
    • 0022382216 scopus 로고
    • The sodium/hydrogen exchange system in cardiac cells: Its biochemical and pharmacological properties and its role in regulating internal concentrations of sodium and internal pH
    • Lazdunski M, Frelin C, Vigne P. The sodium/hydrogen exchange system in cardiac cells: its biochemical and pharmacological properties and its role in regulating internal concentrations of sodium and internal pH. J Mol Cell Cardiol. 1985;17:1029-1042.
    • (1985) J Mol Cell Cardiol. , vol.17 , pp. 1029-1042
    • Lazdunski, M.1    Frelin, C.2    Vigne, P.3
  • 58
    • 0024289816 scopus 로고
    • The regulation of the intracellular pH in cells from vertebrates
    • Frelin C, Vigne P, Ladoux A, Lazdunski M. The regulation of the intracellular pH in cells from vertebrates. Eur J Biochem. 1988; 174:3-14.
    • (1988) Eur J Biochem. , vol.174 , pp. 3-14
    • Frelin, C.1    Vigne, P.2    Ladoux, A.3    Lazdunski, M.4
  • 59
    • 0022970528 scopus 로고
    • Na/H exchange in cultured heart cells: Secondary stimulation of electrogenic transport during recovery from intracellular acidosis
    • Piwnica-Worms D, Jacob R, Shigeto N, Horres, Lieberman M. Na/H exchange in cultured heart cells: secondary stimulation of electrogenic transport during recovery from intracellular acidosis. J Mol Cell Cardiol. 1986;18:1109-1116.
    • (1986) J Mol Cell Cardiol. , vol.18 , pp. 1109-1116
    • Piwnica-Worms, D.1    Jacob, R.2    Shigeto, N.3    Lieberman, M.4
  • 60
    • 0023190884 scopus 로고
    • Relations among sodium pump inhibition. Na-Ca and Na-H exchange activities and Ca-H interactions in cultured chick heart cells
    • Kim D, Cragoe EJ, Smith TW. Relations among sodium pump inhibition. Na-Ca and Na-H exchange activities and Ca-H interactions in cultured chick heart cells. Circ Res. 1987;60:185-193.
    • (1987) Circ Res. , vol.60 , pp. 185-193
    • Kim, D.1    Cragoe, E.J.2    Smith, T.W.3
  • 65
    • 0032576615 scopus 로고    scopus 로고
    • 2+ exchanger increases susceptibility to ischemia/reperfusion injury in male, but not female, transgenic mice
    • 2+ exchanger increases susceptibility to ischemia/reperfusion injury in male, but not female, transgenic mice. Circ Res. 1998;83:1215-1223.
    • (1998) Circ Res. , vol.83 , pp. 1215-1223
    • Cross, H.R.1    Lu, L.2    Steenbergen, C.3    Philipson, K.D.4    Murphy, E.5
  • 67
    • 0027787697 scopus 로고
    • + exchange preserves viability, restores mechanical function, and prevents the pH paradox in reperfusion injury to rat neonatal myocytes
    • + exchange preserves viability, restores mechanical function, and prevents the pH paradox in reperfusion injury to rat neonatal myocytes. Basic Res Cardiol. 1993;88:430-442.
    • (1993) Basic Res Cardiol. , vol.88 , pp. 430-442
    • Harper, I.S.1    Bond, J.M.2    Chacon, E.3    Reece, J.M.4    Herman, B.5    Lemasters, J.J.6
  • 68
    • 0025726641 scopus 로고
    • Amiloride delays the ischemia-induced rise in cytosolic calcium
    • Murphy E, Perlman M, London RE, Steenbergen C. Amiloride delays the ischemia-induced rise in cytosolic calcium. Circ Res. 1991;68: 1250-1258.
    • (1991) Circ Res. , vol.68 , pp. 1250-1258
    • Murphy, E.1    Perlman, M.2    London, R.E.3    Steenbergen, C.4
  • 69
    • 0030239818 scopus 로고    scopus 로고
    • Protective effects of dimethyl amiloride against postischemic myocardial dysfunction in rabbit hearts: Phosphorus 31-nuclear magnetic resonance measurements of intracellular pH and cellular energy
    • Koike A, Akita T, Hotta Y, Takeyka K, Kodama I, Murase M, Abe T, Toyama J. Protective effects of dimethyl amiloride against postischemic myocardial dysfunction in rabbit hearts: phosphorus 31-nuclear magnetic resonance measurements of intracellular pH and cellular energy. J Thorac Cardiovasc Surg. 1996;112:765-775.
    • (1996) J Thorac Cardiovasc Surg. , vol.112 , pp. 765-775
    • Koike, A.1    Akita, T.2    Hotta, Y.3    Takeyka, K.4    Kodama, I.5    Murase, M.6    Abe, T.7    Toyama, J.8
  • 72
    • 0026537649 scopus 로고
    • Protective effects of amiloride on the ischemic reperfused rat heart: Relation to mitochondrial function
    • Duan J, Karmazyn M. Protective effects of amiloride on the ischemic reperfused rat heart: relation to mitochondrial function. Eur J Pharmacol. 1992;210:149-157.
    • (1992) Eur J Pharmacol. , vol.210 , pp. 149-157
    • Duan, J.1    Karmazyn, M.2
  • 77
    • 0030593923 scopus 로고    scopus 로고
    • + exchange inhibitor, on ventricular arrhythmias in animal hearts
    • + exchange inhibitor, on ventricular arrhythmias in animal hearts. Eur J Pharmacol. 1996;317:309-316.
    • (1996) Eur J Pharmacol. , vol.317 , pp. 309-316
    • Xue, Y.X.1    Aye, N.N.2    Hashimoto, K.3
  • 79
    • 0028567695 scopus 로고
    • + exchange and reperfusion arrhythmias: Protection by intracoronary infusion of a novel inhibitor
    • + exchange and reperfusion arrhythmias: protection by intracoronary infusion of a novel inhibitor. Am J Phvsiol. 1994;267:H2430-H2440.
    • (1994) Am J Phvsiol. , vol.267
    • Yasutake, M.1    Ibuki, C.2    Hearse, D.J.3    Avkiran, M.4
  • 82
    • 0031686683 scopus 로고    scopus 로고
    • Dose-dependent reduction of myocardial infarct mass in rabbits by the NHE-1 inhibitor cariporide (HOE 642)
    • Linz W, Albus U, Crause P, Jung W, Weichert A, Schölkens BA, Scholz W. Dose-dependent reduction of myocardial infarct mass in rabbits by the NHE-1 inhibitor cariporide (HOE 642). Clin Exp Hypertens. 1998; 20:733-749.
    • (1998) Clin Exp Hypertens. , vol.20 , pp. 733-749
    • Linz, W.1    Albus, U.2    Crause, P.3    Jung, W.4    Weichert, A.5    Schölkens, B.A.6    Scholz, W.7
  • 83
    • 0031050219 scopus 로고    scopus 로고
    • + exchange inhibitor. Hoe 642: Difference from preconditioning in the role of protein kinase C
    • + exchange inhibitor. Hoe 642: difference from preconditioning in the role of protein kinase C. J Am Coll Cardiol. 1997;29:693-701.
    • (1997) J Am Coll Cardiol. , vol.29 , pp. 693-701
    • Miura, T.1    Ogawa, T.2    Suzuki, K.3    Goto, M.4    Shimamoto, K.5
  • 86
    • 0031468294 scopus 로고    scopus 로고
    • Interaction between anesthetics and the sodium-hydrogen exchange inhibitor 642 (cariporide) in ischemic and reperfused rat hearts
    • Mathur S, Karmazyn M. Interaction between anesthetics and the sodium-hydrogen exchange inhibitor 642 (cariporide) in ischemic and reperfused rat hearts. Anesthesiology. 1997;87:1460-1469.
    • (1997) Anesthesiology , vol.87 , pp. 1460-1469
    • Mathur, S.1    Karmazyn, M.2
  • 90
    • 0031824640 scopus 로고    scopus 로고
    • A new sodium/hydrogen exchange inhibitor. EMD 85131. Limits infarct size in dogs when administered before or after coronary artery occlusion
    • Gumina RJ, Mizumura T, Beier N, Schelling P, Schultz JJ, Gross GJ. A new sodium/hydrogen exchange inhibitor. EMD 85131. limits infarct size in dogs when administered before or after coronary artery occlusion. J Pharmacol Exp Ther. 1998;286:175-183.
    • (1998) J Pharmacol Exp Ther. , vol.286 , pp. 175-183
    • Gumina, R.J.1    Mizumura, T.2    Beier, N.3    Schelling, P.4    Schultz, J.J.5    Gross, G.J.6
  • 91
    • 0027431709 scopus 로고
    • Protective effects of the potent Na/H exchange inhibitor methylisobutyl amiloride against post-ischemic contractile dysfunction in rat and guinea-pig hearts
    • Moffat MP, Karmazyn M. Protective effects of the potent Na/H exchange inhibitor methylisobutyl amiloride against post-ischemic contractile dysfunction in rat and guinea-pig hearts. J Mol Cell Cardiol. 1993;25:959-971.
    • (1993) J Mol Cell Cardiol. , vol.25 , pp. 959-971
    • Moffat, M.P.1    Karmazyn, M.2
  • 92
    • 0027161197 scopus 로고
    • Effect of amiloride and selected analogues on postischemic recovery of cardiac contractile function
    • Meng H-P, Maddaford TG, Pierce GN. Effect of amiloride and selected analogues on postischemic recovery of cardiac contractile function. Am J Physiol. 1993;264:H1831-H1835.
    • (1993) Am J Physiol. , vol.264
    • Meng, H.-P.1    Maddaford, T.G.2    Pierce, G.N.3
  • 94
    • 0343307138 scopus 로고    scopus 로고
    • Death by design: Programmed cell death in cardiovascular biology and disease
    • MacLellan WR, Schneider MD. Death by design: programmed cell death in cardiovascular biology and disease. Circ Res. 1997;81:137-144.
    • (1997) Circ Res. , vol.81 , pp. 137-144
    • MacLellan, W.R.1    Schneider, M.D.2
  • 95
    • 0029885316 scopus 로고    scopus 로고
    • Preconditioning in rabbit cardiomyocytes: Role of pH. Vacuolar proton ATPase, and apoptosis
    • Gottlieb RA, Gruol DL, Zhu JY, Engler RL. Preconditioning in rabbit cardiomyocytes: role of pH. vacuolar proton ATPase, and apoptosis. J Clin Invest. 1996;97:2391-2398.
    • (1996) J Clin Invest. , vol.97 , pp. 2391-2398
    • Gottlieb, R.A.1    Gruol, D.L.2    Zhu, J.Y.3    Engler, R.L.4
  • 96
    • 0031281389 scopus 로고    scopus 로고
    • A rapid ischemia-induced apoptosis in isolated rat hearts and its attenuation by the sodium-hydrogen exchange inhibitor HOE 642 (Cariporide)
    • Chakrabarti S, Hoque ANE, Karmazyn M. A rapid ischemia-induced apoptosis in isolated rat hearts and its attenuation by the sodium-hydrogen exchange inhibitor HOE 642 (Cariporide). J Mol Cell Cardiol. 1997;29:3169-3174.
    • (1997) J Mol Cell Cardiol. , vol.29 , pp. 3169-3174
    • Chakrabarti, S.1    Hoque, A.N.E.2    Karmazyn, M.3
  • 97
    • 0026656748 scopus 로고
    • Ischemic preconditioning attenuates acidosis and postischemic dysfunction in isolated rat heart
    • Asimakis GK, Inners-McBride K, Medellin G, Conti VR. Ischemic preconditioning attenuates acidosis and postischemic dysfunction in isolated rat heart. Am J Physiol. 1992;263:H887-H894.
    • (1992) Am J Physiol. , vol.263
    • Asimakis, G.K.1    Inners-McBride, K.2    Medellin, G.3    Conti, V.R.4
  • 99
    • 0029082364 scopus 로고    scopus 로고
    • Ischemic preconditioning stimulates sodium and proton transport in isolated rat hearts
    • Ramasamy R, Liu H, Anderson S, Lundmark K, Schaefer S. Ischemic preconditioning stimulates sodium and proton transport in isolated rat hearts. J Clin Invest. 1998;96:1464-1472.
    • (1998) J Clin Invest. , vol.96 , pp. 1464-1472
    • Ramasamy, R.1    Liu, H.2    Anderson, S.3    Lundmark, K.4    Schaefer, S.5
  • 100
    • 0030861081 scopus 로고    scopus 로고
    • Is calcium a mediator of infarct size reduction with preconditioning in canine myocardium?
    • Przyklenk K, Hata K, Kloner RA. Is calcium a mediator of infarct size reduction with preconditioning in canine myocardium? Circulation. 1997;96:1305-1312.
    • (1997) Circulation , vol.96 , pp. 1305-1312
    • Przyklenk, K.1    Hata, K.2    Kloner, R.A.3
  • 102
    • 0028820985 scopus 로고
    • Inhibition of sodium-hydrogen exchange reduces infarct size in the isolated rat heart: A protective additive to ischaemic preconditioning
    • Bugge E, Ytrehus K. Inhibition of sodium-hydrogen exchange reduces infarct size in the isolated rat heart: a protective additive to ischaemic preconditioning. Cardiovasc Res. 1995;29:269-274.
    • (1995) Cardiovasc Res. , vol.29 , pp. 269-274
    • Bugge, E.1    Ytrehus, K.2
  • 104
    • 0029683967 scopus 로고    scopus 로고
    • The role of endothelins in cardiac function in health and disease
    • Karmazyn M. ed. Basel, Switzerland: Birkhäuser;
    • Karmazyn, M. The role of endothelins in cardiac function in health and disease. In: Karmazyn M. ed. Myocardial Ischemia: Mechanisms, Reperfusion, Protection. Basel, Switzerland: Birkhäuser; 1996: 209-230.
    • (1996) Myocardial Ischemia: Mechanisms, Reperfusion, Protection , pp. 209-230
  • 105
    • 0028795596 scopus 로고
    • 1 adrenergic stimulation: A potential role for receptor mediated activation of sarcolemmal sodium-hydrogen exchange
    • 1 adrenergic stimulation: a potential role for receptor mediated activation of sarcolemmal sodium-hydrogen exchange. Cardiovasc Res. 1995;29: 222-230.
    • (1995) Cardiovasc Res. , vol.29 , pp. 222-230
    • Yasutake, M.1    Avkiran, M.2
  • 106
    • 0021741946 scopus 로고
    • Role of glycolytic products in damage to ischemic myocardium: Dissociation of adenosine triphosphate levels and recovery of function of reperfused ischemic hearts
    • Neely JR, Grotyohann LW. Role of glycolytic products in damage to ischemic myocardium: dissociation of adenosine triphosphate levels and recovery of function of reperfused ischemic hearts. Circ Res. 1984;55: 816-824.
    • (1984) Circ Res. , vol.55 , pp. 816-824
    • Neely, J.R.1    Grotyohann, L.W.2
  • 107
    • 0029080582 scopus 로고
    • Is lactate-induced myocardial ischaemic injury mediated by decreased ph or increased intracellular lactate?
    • Cross HR, Clarke K, Opie LH, Radda GK. Is lactate-induced myocardial ischaemic injury mediated by decreased pH or increased intracellular lactate? J Mol Cell Cardiol. 1995;27:1369-1381.
    • (1995) J Mol Cell Cardiol. , vol.27 , pp. 1369-1381
    • Cross, H.R.1    Clarke, K.2    Opie, L.H.3    Radda, G.K.4
  • 108
    • 0027473280 scopus 로고
    • + exchange inhibitors reverse lactate-induced depression in postischaemic ventricular recovery
    • + exchange inhibitors reverse lactate-induced depression in postischaemic ventricular recovery. Br J Pharmacol. 1993;108:50-56.
    • (1993) Br J Pharmacol. , vol.108 , pp. 50-56
    • Karmazyn, M.1
  • 109
    • 0030835256 scopus 로고    scopus 로고
    • Effect of sodium-hydrogen exchange inhibition on functional and metabolic impairment produced by oxidative stress in the isolated rat heart
    • Hoque ANE, Karmazyn M. Effect of sodium-hydrogen exchange inhibition on functional and metabolic impairment produced by oxidative stress in the isolated rat heart. Can J Physiol Pharmacol. 1997;75: 326-334.
    • (1997) Can J Physiol Pharmacol. , vol.75 , pp. 326-334
    • Hoque, A.N.E.1    Karmazyn, M.2
  • 110
    • 0032211555 scopus 로고    scopus 로고
    • Hydrogen peroxide induced impairment of post-ischemic ventricular function is prevented by the sodium-hydrogen exchange inhibitor HOE 642 (cariporide)
    • Myers ML, Farhangkhoee P, Karmazyn M. Hydrogen peroxide induced impairment of post-ischemic ventricular function is prevented by the sodium-hydrogen exchange inhibitor HOE 642 (cariporide). Cardiovasc Res. 1998;40:290-296.
    • (1998) Cardiovasc Res. , vol.40 , pp. 290-296
    • Myers, M.L.1    Farhangkhoee, P.2    Karmazyn, M.3
  • 114
    • 0029681698 scopus 로고    scopus 로고
    • Response to ischemia and reperfusion by the diabetic heart
    • Karmazyn M, ed. Basel. Switzerland: Birkhauser
    • Feuvray D. Response to ischemia and reperfusion by the diabetic heart. In: Karmazyn M, ed. Mvocardial Ischemia: Mechanisms, Reperfusion, Protection. Basel. Switzerland: Birkhauser; 1996:409-421.
    • (1996) Mvocardial Ischemia: Mechanisms, Reperfusion, Protection , pp. 409-421
    • Feuvray, D.1
  • 117
    • 0027204172 scopus 로고
    • + exchange inhibitors decrease neointimal formation after rat carotid injury: Effects on smooth muscle cell migration and proliferation
    • + exchange inhibitors decrease neointimal formation after rat carotid injury: effects on smooth muscle cell migration and proliferation. Circ Res. 1993;73:269-275.
    • (1993) Circ Res. , vol.73 , pp. 269-275
    • Mitsuka, M.1    Nagae, M.2    Berk, B.C.3
  • 118
    • 0031576532 scopus 로고    scopus 로고
    • Angiotensin II mediates cell hypertrophy in vascular smooth muscle cell cultures from hypertensive Ren-2 transgenic rats by an amiloride- and furosemide-sensitive mechanism
    • Peiro C, Angulo J, Llergo JL, Rodriguez-Manas L, Marin J, Sanchez-Ferrer CF. Angiotensin II mediates cell hypertrophy in vascular smooth muscle cell cultures from hypertensive Ren-2 transgenic rats by an amiloride- and furosemide-sensitive mechanism. Biochem Biophys Res Commun. 1997;240:367-371.
    • (1997) Biochem Biophys Res Commun. , vol.240 , pp. 367-371
    • Peiro, C.1    Angulo, J.2    Llergo, J.L.3    Rodriguez-Manas, L.4    Marin, J.5    Sanchez-Ferrer, C.F.6
  • 120
    • 0032547857 scopus 로고    scopus 로고
    • Stretch-induced alkalinization of feline papillary muscle: An autocrine-paracrine system
    • Cingolani HE, Alvarez BV, Ennis IL, Camillión de Hurtado MC. Stretch-induced alkalinization of feline papillary muscle: an autocrine-paracrine system. Circ Res. 1998;83:775-780.
    • (1998) Circ Res. , vol.83 , pp. 775-780
    • Cingolani, H.E.1    Alvarez, B.V.2    Ennis, I.L.3    Camillión De Hurtado, M.C.4
  • 124
    • 84878692244 scopus 로고    scopus 로고
    • + exchange inhibition attenuates hypertrophy and heart failure in one-week postinfarcted rat myocardium
    • In press
    • + exchange inhibition attenuates hypertrophy and heart failure in one-week postinfarcted rat myocardium. Am J Physiol. In press.
    • Am J Physiol.
    • Yoshida, H.1    Karmazyn, M.2
  • 125
    • 0032547810 scopus 로고    scopus 로고
    • + exchanger and cardiac hypertrophy
    • + exchanger and cardiac hypertrophy. Circ Res. 1998;83:870-873.
    • (1998) Circ Res. , vol.83 , pp. 870-873
    • Dostal, D.E.1    Baker, K.M.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.