The role of ASICs in cerebral ischemia

Wiley Interdisciplinary Reviews: Membrane Transport and Signaling

Volumn 1, Issue 5, 2012, Pages 655-662

  Xiong, Zhi Gang ^a   Xu, Tian Le ^b  

^a MOREHOUSE SCHOOL OF MEDICINE   (United States)

^b SHANGHAI JIAO TONG UNIVERSITY SCHOOL OF MEDICINE   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ACID SENSING ION CHANNEL; ACID SENSING ION CHANNEL 1A; ARACHIDONIC ACID; CALCIUM CALMODULIN DEPENDENT PROTEIN KINASE II; DYNORPHIN; LACTIC ACID; NITRIC OXIDE; PROTEINASE; SPERMINE; UNCLASSIFIED DRUG;

ACID SENSING ION CHANNEL 1 GENE; ACIDOSIS; ARTICLE; BRAIN ACIDOSIS; BRAIN DISEASE; BRAIN ISCHEMIA; BRAIN NERVE CELL; DISEASE ASSOCIATION; GENE ACTIVATION; GENE EXPRESSION REGULATION; GENE INACTIVATION; HUMAN; NEUROMODULATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION;

EID: 84879194438     PISSN: 2190460X     EISSN: 21904618     Source Type: Journal    
DOI: 10.1002/wmts.57     Document Type: Article

References (61)

1. Weintraub MI. Thrombolysis (tissue plasminogen activator) in stroke: a medicolegal quagmire. Stroke 2006, 37:1917-1922.
2. Choi DW. Calcium-mediated neurotoxicity: relationship to specific channel types and role in ischemic damage. Trends Neurosci 1988, 11:465-469.
3. Lee JM, Zipfel GJ, Choi DW. The changing landscape of ischaemic brain injury mechanisms. Nature 1999, 399:A7-A14.
4. Simonian NA, Coyle JT. Oxidative stress in neurodegenerative diseases. Annu Rev Pharmacol Toxicol 1996, 36:83-106.
5. Coyle JT, Puttfarcken P. Oxidative stress, glutamate, and neurodegenerative disorders. Science 1993, 262: 689-695.
6. Polster BM, Fiskum G. Mitochondrial mechanisms of neural cell apoptosis. J Neurochem 2004, 90: 1281-1289.
7. Ikonomidou C, Turski L. Why did NMDA receptor antagonists fail clinical trials for stroke and traumatic brain injury? Lancet Neurol 2002, 1: 383-386.
8. Siesjo BK, Katsura K, Kristian T. Acidosis-related damage. Adv Neurol 1996, 71:209-233.
9. Tombaugh GC, Sapolsky RM. Evolving concepts about the role of acidosis in ischemic neuropathology. J Neurochem 1993, 61:793-803.
10. Nedergaard M, Kraig RP, Tanabe J, Pulsinelli WA. Dynamics of interstitial and intracellular pH in evolving brain infarct. Am J Physiol 1991, 260:R581-R588.
11. Rehncrona S. Brain acidosis. Ann Emerg Med 1985, 14:770-776.
12. Wemmie JA, Price MP, Welsh MJ. Acid-sensing ion channels: advances, questions and therapeutic opportunities. Trends Neurosci 2006, 29:578-586.
13. Swanson RA, Farrell K, Simon RP. Acidosis causes failure of astrocyte glutamate uptake during hypoxia. J Cereb Blood Flow Metab 1995, 15:417-424.
14. McDonald JW, Bhattacharyya T, Sensi SL, Lobner D, Ying HS, Canzoniero LMT, Choi DW. Extracellular acidity potentiates AMPA receptor-mediated cortical neuronal death. J Neurosci 1998, 18:6290-6299.
15. Xiong ZG, Zhu XM, Chu XP, Minami M, Hey J, Wei WL, MacDonald JF, Wemmie JA, Price MP, Welsh MJ, et al. Neuroprotection in ischemia: blocking calcium-permeable Acid-sensing ion channels. Cell 2004, 118:687-698.
16. Waldmann R, Champigny G, Bassilana F, Heurteaux C, Lazdunski M. A proton-gated cation channel involved in acid-sensing. Nature 1997, 386:173-177.
17. Mari Y, Katnik C, Cuevas J. ASIC1a channels are activated by endogenous protons during ischemia and contribute to synergistic potentiation of intracellular Ca(2+) overload during ischemia and acidosis. Cell Calcium 2010, 48:70-82.
18. Yermolaieva O, Leonard AS, Schnizler MK, Abboud FM, Welsh MJ. Extracellular acidosis increases neuronal cell calcium by activating acid-sensing ion channel 1a. Proc Natl Acad Sci U S A 2004, 101:6752-6757.
19. Sherwood TW, Lee KG, Gormley MG, Askwith CC. Heteromeric acid-sensing ion channels (ASICs) composed of ASIC2b and ASIC1a display novel channel properties and contribute to acidosis-induced neuronal death. J Neurosci 2011, 31:9723-9734.
20. Pignataro G, Simon RP, Xiong ZG. Prolonged activation of ASIC1a and the time window for neuroprotection in cerebral ischaemia. Brain 2007, 130:151-158.
21. Biegon A, Fry PA, Paden CM, Alexandrovich A, Tsenter J, Shohami E. Dynamic changes in N-methyl-d-aspartate receptors after closed head injury in mice: implications for treatment of neurological and cognitive deficits. Proc Natl Acad Sci U S A 2004, 101: 5117-5122.
22. Li M, Inoue K, Branigan D, Kratzer E, Hansen JC, Chen JW, Simon RP, Xiong Z-G. Acid-sensing ion channels in acidosis-induced injury of human brain neurons. J Cereb Blood Flow Metab 2010, 30:1247-1260.
23. Hesselager M, Timmermann DB, Ahring PK. pH dependency and desensitization kinetics of heterologously expressed combinations of acid-sensing ion channel subunits. J Biol Chem 2004, 279:11006-11015.
24. Krishtal O. The ASICs: signaling molecules? Modulators? Trends Neurosci 2003, 26:477-483.
25. Grunder S, Chen X. Structure, function, and pharmacology of acid-sensing ion channels (ASICs): focus on ASIC1a. Int J Physiol Pathophysiol Pharmacol 2010, 2:73-94.
26. 2+ concentrations. J Exp Biol 1998, 201:1141-1152.
27. Chu XP, Papasian CJ, Wang JQ, Xiong ZG. Modulation of acid-sensing ion channels: molecular mechanisms and therapeutic potential. Int J Physiol Pathophysiol Pharmacol 2011, 3:288-309.
28. Farooqui AA, Horrocks LA. Phospholipase A2-generated lipid mediators in the brain: the good, the bad, and the ugly. Neuroscientist 2006, 12:245-260.
29. Siesjo BK, Katsura K. Ischemic brain damage: focus on lipids and lipid mediators. Adv Exp Med Biol 1992, 318:41-56.
30. Miller B, Sarantis M, Traynelis SF, Attwell D. Potentiation of NMDA receptor currents by arachidonic acid. Nature 1992, 355:722-725.
31. Allen NJ, Attwell D. Modulation of ASIC channels in rat cerebellar Purkinje neurons by ischemia-related signals. J Physiol (Lond) 2002, 543:521-529.
32. Smith ES, Cadiou H, McNaughton PA. Arachidonic acid potentiates acid-sensing ion channels in rat sensory neurons by a direct action. Neuroscience 2007, 145:686-698.
33. Coultrap SJ, Vest RS, Ashpole NM, Hudmon A, Bayer KU. CaMKII in cerebral ischemia. Acta Pharmacol Sin 2011, 32:861-872.
34. Gao J, Duan B, Wang D-G, Deng X-H, Zhang G-Y, Xu L, Xu T-L. Coupling between NMDA receptor and acid-sensing ion channel contributes to ischemic neuronal death. Neuron 2005, 48:635-646.
35. Hauser KF, Foldes JK, Turbek CS. Dynorphin A (1-13) neurotoxicity in vitro: opioid and non-opioid mechanisms in mouse spinal cord neurons. Exp Neurol 1999, 160:361-375.
36. Sherwood TW, Askwith CC. Dynorphin opioid peptides enhance acid-sensing ion channel 1a activity and acidosis-induced neuronal death. J Neurosci 2009, 29:14371-14380.
37. + channel on ischemia-sensing neurons. Nat Neurosci 2001, 4:869-870.
38. Xiong ZG, MacDonald JF. Sensing of extracellular calcium by neurones. Can J Physiol Pharmacol 1999, 77:715-721.
39. Hess P, Lansman JB, Tsien RW. Calcium channel selectivity for divalent and monovalent cations. Voltage and concentration dependence of single channel current in ventricular heart cells. J Gen Physiol 1986, 88: 293-319.
40. Zhou W, Jones SW. Surface charge and calcium channel saturation in bullfrog sympathetic neurons. J Gen Physiol 1995, 105:441-462.
41. Star RA. Nitric oxide. Am J Med Sci 1993, 306: 348-358.
42. Schulz JB, Matthews RT, Klockgether T, Dichgans J, Beal MF. The role of mitochondrial dysfunction and neuronal nitric oxide in animal models of neurodegenerative diseases. Mol Cell Biochem 1997, 174:193-197.
43. Bolanos JP, Almeida A. Roles of nitric oxide in brain hypoxia-ischemia. Biochim Biophys Acta 1999, 1411: 415-436.
44. Boje KM, Arora PK. Microglial-produced nitric oxide and reactive nitrogen oxides mediate neuronal cell death. Brain Res 1992, 587:250-256.
45. Cadiou H, Studer M, Jones NG, Smith E StJ, Ballard A, McMahan SB, McNaughton PA. Modulation of acid-sensing ion channel activity by nitric oxide. J Neurosci 2007, 27:13251-13260.
46. Gingrich MB, Traynelis SF. Serine proteases and brain damage - is there a link? Trends Neurosci 2000, 23:399-407.
47. Vivien D, Buisson A. Serine protease inhibitors: novel therapeutic targets for stroke? J Cereb Blood Flow Metab 2000, 20:755-764.
48. Poirot O, Vukicevic M, Boesch A, Kellenberger S. Selective regulation of acid-sensing ion channel 1 by serine proteases. J Biol Chem 2004, 279:38448-38457.
49. Vukicevic M, Weder G, Boillat A, Boesch A, Kellenberger S. Trypsin cleaves acid-sensing ion channel 1a in a domain that is critical for channel gating. J Biol Chem 2006, 281:714-722.
50. Toninello A, Salvi M, Mondovi B. Interaction of biologically active amines with mitochondria and their role in the mitochondrial-mediated pathway of apoptosis. Curr Med Chem 2004, 11:2349-2374.
51. Kindy MS, Hu Y, Dempsey RJ. Blockade of ornithine decarboxylase enzyme protects against ischemic brain damage. J Cereb Blood Flow Metab 1994, 14: 1040-1045.
52. Benveniste M, Mayer ML. Multiple effects of spermine on N-methyl-d-aspartic acid receptor responses of rat cultured hippocampal neurones. J Physiol 1993, 464:131-163.
53. Rock DM, Macdonald RL. Polyamine regulation of N-methyl-d-aspartate receptor channels. Annu Rev Pharmacol Toxicol 1995, 35:463-482.
54. Johnson TD. Polyamines and cerebral ischemia. Prog Drug Res 1998, 50:193-258.
55. Li J, Doyle KM, Tatlisumak T. Polyamines in the brain: distribution, biological interactions, and their potential therapeutic role in brain ischaemia. Curr Med Chem 2007, 14:1807-1813.
56. Babini E, Paukert M, Geisler HS, Grunder S. Alternative splicing and interaction with di- and polyvalent cations control the dynamic range of acid-sensing ion channel 1 (ASIC1). J Biol Chem 2002, 277:41597-41603.
57. Duan B, Wang Y-Z, Yang T, Chu X-P, Yu Y, Huang Y, Cao H, Hansen J, Simon RP, et al. Extracellular spermine exacerbates ischemic neuronal injury through sensitization of ASIC1a channels to extracellular acidosis. J Neurosci 2011, 31:2101-2112.
58. Pignataro G, Cuomo O, Esposito E, Sirabell R, Renzo Di, Annunziato GL. ASIC1a contributes to neuroprotection elicited by ischemic preconditioning and postconditioning. Int J Physiol Pathophysiol Pharmacol 2011, 3:1-8.
59. Chai S, Li M, Branigan D, Xiong ZG, Simon RP. Activation of acid-sensing ion channel 1a (ASIC1a) by surface trafficking. J Biol Chem 2010, 285:13002-13011.
60. Allen NJ, Attwell D. Modulation of ASIC channels in rat cerebellar Purkinje neurons by ischaemia-related signals. J Physiol 2002, 543:521-529.
61. Jetti SK, Swain SM, Majumder S, Chatterjee S, Poornima V, Bera AK. Evaluation of the role of nitric oxide in acid sensing ion channel mediated cell death. Nitric Oxide 2010, 22:213-219.