Na+/H+ Exchanger Inhibitor, SM-20220, Is Protective Against Excitotoxicity in Cultured Cortical Neurons

Stroke

Volumn 35, Issue 1, 2004, Pages 185-190

  Matsumoto, Yuji ^a   Yamamoto, Seiji ^a   Suzuki, Yasuhiro ^a   Tsuboi, Takashi ^a   Terakawa, Susumu ^a   Ohashi, Naohito ^b   Umemura, Kazuo ^a  

^a HAMAMATSU UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b DAINIPPON SUMITOMO PHARMA CO LTD   (Japan)

Author keywords

Excitotoxicity; Glutamates; Na+ H+ exchanger; Neuronal death; Rats

Indexed keywords

CALCIUM; DIZOCILPINE; GLUTAMIC ACID; PROTEIN INHIBITOR; SM 20220; SODIUM PROTON EXCHANGE PROTEIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BRAIN CELL; BRAIN ISCHEMIA; CALCIUM CELL LEVEL; CELL PH; CELL SWELLING; CONFOCAL LASER MICROSCOPY; CONTROLLED STUDY; DOSE RESPONSE; FLUORESCENCE; NERVE CELL NECROSIS; NEUROPROTECTION; NONHUMAN; PRIORITY JOURNAL; RAT; REPERFUSION INJURY;

AMIDES; ANIMALS; CALCIUM; CELL DEATH; CELLS, CULTURED; CEREBRAL CORTEX; DOSE-RESPONSE RELATIONSHIP, DRUG; EXCITATORY AMINO ACID ANTAGONISTS; GLUTAMIC ACID; HYDROGEN-ION CONCENTRATION; INDOLES; INTRACELLULAR FLUID; NEURONS; NEUROPROTECTIVE AGENTS; NEUROTOXINS; RATS; RATS, WISTAR; SODIUM-HYDROGEN ANTIPORTER;

EID: 0346095481     PISSN: 00392499     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.STR.0000106910.42815.C2     Document Type: Article

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