-
1
-
-
4344580888
-
Strategies for disease modification in Alzheimer's disease
-
10.1038/nrn1495 15322526 1:CAS:528:DC%2BD2cXmvVaqsr8%3D 10.1038/nrn1495
-
Citron M (2004) Strategies for disease modification in Alzheimer's disease. Nat Rev Neurosci 5(9):677-685. doi: 10.1038/nrn1495
-
(2004)
Nat Rev Neurosci
, vol.5
, Issue.9
, pp. 677-685
-
-
Citron, M.1
-
2
-
-
77951028451
-
Diabetes-accelerated memory dysfunction via cerebrovascular inflammation and Abeta deposition in an Alzheimer mouse model with diabetes
-
10.1073/pnas.1000645107 20231468 1:CAS:528:DC%2BC3cXltFSjt7k%3D 10.1073/pnas.1000645107
-
Takeda S, Sato N, Uchio-Yamada K, Sawada K, Kunieda T, Takeuchi D, Kurinami H, Shinohara M, Rakugi H, Morishita R (2010) Diabetes-accelerated memory dysfunction via cerebrovascular inflammation and Abeta deposition in an Alzheimer mouse model with diabetes. Proc Natl Acad Sci U S A 107(15):7036-7041. doi: 10.1073/pnas.1000645107
-
(2010)
Proc Natl Acad Sci U S A
, vol.107
, Issue.15
, pp. 7036-7041
-
-
Takeda, S.1
Sato, N.2
Uchio-Yamada, K.3
Sawada, K.4
Kunieda, T.5
Takeuchi, D.6
Kurinami, H.7
Shinohara, M.8
Rakugi, H.9
Morishita, R.10
-
3
-
-
84880185976
-
Discoveries of tau, abnormally hyperphosphorylated tau and others of neurofibrillary degeneration: A personal historical perspective
-
16914861 1:CAS:528:DC%2BD28XotFKktL4%3D
-
Iqbal K, Grundke-Iqbal I (2006) Discoveries of tau, abnormally hyperphosphorylated tau and others of neurofibrillary degeneration: a personal historical perspective. J Alzheimers Dis 9(3 Suppl):219-242
-
(2006)
J Alzheimers Dis
, vol.9
, Issue.3 SUPPL.
, pp. 219-242
-
-
Iqbal, K.1
Grundke-Iqbal, I.2
-
4
-
-
75149182840
-
Depression and advanced complications of diabetes: A prospective cohort study
-
10.2337/dc09-1068 19933989 10.2337/dc09-1068
-
Lin EH, Rutter CM, Katon W, Heckbert SR, Ciechanowski P, Oliver MM, Ludman EJ, Young BA, Williams LH, McCulloch DK, Von Korff M (2010) Depression and advanced complications of diabetes: a prospective cohort study. Diabetes Care 33(2):264-269. doi: 10.2337/dc09-1068
-
(2010)
Diabetes Care
, vol.33
, Issue.2
, pp. 264-269
-
-
Lin, E.H.1
Rutter, C.M.2
Katon, W.3
Heckbert, S.R.4
Ciechanowski, P.5
Oliver, M.M.6
Ludman, E.J.7
Young, B.A.8
Williams, L.H.9
McCulloch, D.K.10
Von Korff, M.11
-
5
-
-
62349104344
-
Effect of a lifestyle intervention on change in cardiorespiratory fitness in adults with type 2 diabetes: Results from the Look AHEAD Study
-
10.1038/ijo.2008.280 1:STN:280:DC%2BD1M3gs1ylsw%3D%3D 10.1038/ijo.2008.280
-
Jakicic JM, Jaramillo SA, Balasubramanyam A, Bancroft B, Curtis JM, Mathews A, Pereira M, Regensteiner JG, Ribisl PM, Look ASG (2009) Effect of a lifestyle intervention on change in cardiorespiratory fitness in adults with type 2 diabetes: results from the Look AHEAD Study. Int J Obes 33(3):305-316. doi: 10.1038/ijo.2008.280
-
(2009)
Int J Obes
, vol.33
, Issue.3
, pp. 305-316
-
-
Jakicic, J.M.1
Jaramillo, S.A.2
Balasubramanyam, A.3
Bancroft, B.4
Curtis, J.M.5
Mathews, A.6
Pereira, M.7
Regensteiner, J.G.8
Ribisl, P.M.9
Look, A.S.G.10
-
6
-
-
0042570843
-
Protein-protein interaction in insulin signaling and the molecular mechanisms of insulin resistance
-
10.1172/JCI6609 10194465 1:CAS:528:DyaK1MXitlegs78%3D 10.1172/JCI6609
-
Virkamaki A, Ueki K, Kahn CR (1999) Protein-protein interaction in insulin signaling and the molecular mechanisms of insulin resistance. J Clin Investig 103(7):931-943. doi: 10.1172/JCI6609
-
(1999)
J Clin Investig
, vol.103
, Issue.7
, pp. 931-943
-
-
Virkamaki, A.1
Ueki, K.2
Kahn, C.R.3
-
7
-
-
15244351255
-
Impaired insulin and insulin-like growth factor expression and signaling mechanisms in Alzheimer's disease - Is this type 3 diabetes?
-
15750215 1:CAS:528:DC%2BD2MXhvVSrtL8%3D
-
Steen E, Terry BM, Rivera EJ, Cannon JL, Neely TR, Tavares R, Xu XJ, Wands JR, de la Monte SM (2005) Impaired insulin and insulin-like growth factor expression and signaling mechanisms in Alzheimer's disease - is this type 3 diabetes? J Alzheimers Dis 7(1):63-80
-
(2005)
J Alzheimers Dis
, vol.7
, Issue.1
, pp. 63-80
-
-
Steen, E.1
Terry, B.M.2
Rivera, E.J.3
Cannon, J.L.4
Neely, T.R.5
Tavares, R.6
Xu, X.J.7
Wands, J.R.8
De La Monte, S.M.9
-
8
-
-
33644591150
-
Insulin and insulin-like growth factor expression and function deteriorate with progression of Alzheimer's disease: Link to brain reductions in acetylcholine
-
16340083 1:CAS:528:DC%2BD2MXht1ynsLjF
-
Rivera EJ, Goldin A, Fulmer N, Tavares R, Wands JR, de la Monte SM (2005) Insulin and insulin-like growth factor expression and function deteriorate with progression of Alzheimer's disease: link to brain reductions in acetylcholine. J Alzheimers Dis 8(3):247-268
-
(2005)
J Alzheimers Dis
, vol.8
, Issue.3
, pp. 247-268
-
-
Rivera, E.J.1
Goldin, A.2
Fulmer, N.3
Tavares, R.4
Wands, J.R.5
De La Monte, S.M.6
-
9
-
-
84859498019
-
Neurodegeneration in diabetes mellitus
-
10.1007/978-1-4614-0653-219 22411248 1:CAS:528:DC%2BC38XhvVClsLvL 10.1007/978-1-4614-0653-2-19
-
Umegaki H (2012) Neurodegeneration in diabetes mellitus. Adv Exp Med Biol 724:258-265. doi: 10.1007/978-1-4614-0653-219
-
(2012)
Adv Exp Med Biol
, vol.724
, pp. 258-265
-
-
Umegaki, H.1
-
10
-
-
79952449386
-
Insulin-resistant brain state: The culprit in sporadic Alzheimer's disease?
-
10.1016/j.arr.2011.01.001 21262392 1:CAS:528:DC%2BC3MXjtFWjtbw%3D 10.1016/j.arr.2011.01.001
-
Correia SC, Santos RX, Perry G, Zhu X, Moreira PI, Smith MA (2011) Insulin-resistant brain state: the culprit in sporadic Alzheimer's disease? Ageing Res Rev 10(2):264-273. doi: 10.1016/j.arr.2011.01.001
-
(2011)
Ageing Res Rev
, vol.10
, Issue.2
, pp. 264-273
-
-
Correia, S.C.1
Santos, R.X.2
Perry, G.3
Zhu, X.4
Moreira, P.I.5
Smith, M.A.6
-
11
-
-
3543067962
-
Neurodegenerative disorders associated with diabetes mellitus
-
10.1007/s00109-004-0552-1 15175861 10.1007/s00109-004-0552-1
-
Ristow M (2004) Neurodegenerative disorders associated with diabetes mellitus. J Mol Med 82(8):510-529. doi: 10.1007/s00109-004-0552-1
-
(2004)
J Mol Med
, vol.82
, Issue.8
, pp. 510-529
-
-
Ristow, M.1
-
12
-
-
30444445996
-
Insulin-secreting cells derived from stem cells: Clinical perspectives, hypes and hopes
-
10.1016/j.trim.2005.09.008 16412956 1:CAS:528:DC%2BD28XksVWntQ%3D%3D 10.1016/j.trim.2005.09.008
-
Roche E, Reig JA, Campos A, Paredes B, Isaac JR, Lim S, Calne RY, Soria B (2005) Insulin-secreting cells derived from stem cells: clinical perspectives, hypes and hopes. Transpl Immunol 15(2):113-129. doi: 10.1016/j.trim.2005.09.008
-
(2005)
Transpl Immunol
, vol.15
, Issue.2
, pp. 113-129
-
-
Roche, E.1
Reig, J.A.2
Campos, A.3
Paredes, B.4
Isaac, J.R.5
Lim, S.6
Calne, R.Y.7
Soria, B.8
-
13
-
-
1842734649
-
Modulation of memory by insulin and glucose: Neuropsychological observations in Alzheimer's disease
-
10.1016/j.ejphar.2004.02.048 15094077 1:CAS:528:DC%2BD2cXjt1Shsbo%3D 10.1016/j.ejphar.2004.02.048
-
Watson GS, Craft S (2004) Modulation of memory by insulin and glucose: neuropsychological observations in Alzheimer's disease. Eur J Pharmacol 490(1-3):97-113. doi: 10.1016/j.ejphar.2004.02.048
-
(2004)
Eur J Pharmacol
, vol.490
, Issue.1-3
, pp. 97-113
-
-
Watson, G.S.1
Craft, S.2
-
14
-
-
33747104566
-
Links between Alzheimer's disease and diabetes
-
10.1358/dot.2006.42.7.973588 16894402 1:CAS:528:DC%2BD28XhtFamsLzJ 10.1358/dot.2006.42.7.973588
-
Sun MK, Alkon DL (2006) Links between Alzheimer's disease and diabetes. Drugs today 42(7):481-489. doi: 10.1358/dot.2006.42.7.973588
-
(2006)
Drugs Today
, vol.42
, Issue.7
, pp. 481-489
-
-
Sun, M.K.1
Alkon, D.L.2
-
15
-
-
1842785179
-
Glucose metabolism and insulin receptor signal transduction in Alzheimer disease
-
10.1016/j.ejphar.2004.02.049 15094078 1:CAS:528:DC%2BD2cXjt1Shsbs%3D 10.1016/j.ejphar.2004.02.049
-
Hoyer S (2004) Glucose metabolism and insulin receptor signal transduction in Alzheimer disease. Eur J Pharmacol 490(1-3):115-125. doi: 10.1016/j.ejphar.2004.02.049
-
(2004)
Eur J Pharmacol
, vol.490
, Issue.1-3
, pp. 115-125
-
-
Hoyer, S.1
-
16
-
-
0032764016
-
Diabetes mellitus and the risk of dementia: The Rotterdam Study
-
10599761 1:STN:280:DC%2BD3c%2Fms1Ontg%3D%3D 10.1212/WNL.53.9.1937
-
Ott A, Stolk RP, van Harskamp F, Pols HA, Hofman A, Breteler MM (1999) Diabetes mellitus and the risk of dementia: the Rotterdam Study. Neurology 53(9):1937-1942
-
(1999)
Neurology
, vol.53
, Issue.9
, pp. 1937-1942
-
-
Ott, A.1
Stolk, R.P.2
Van Harskamp, F.3
Pols, H.A.4
Hofman, A.5
Breteler, M.M.6
-
17
-
-
33751570625
-
Diabetes mellitus and dementia
-
1:CAS:528:DC%2BD2sXhvVKhsA%3D%3D 10.1016/S1262-3636(07)70298-7
-
Pasquier F, Boulogne A, Leys D, Fontaine P (2006) Diabetes mellitus and dementia. Diabetes Metabol 32(5 Pt 1):403-414
-
(2006)
Diabetes Metabol
, vol.32
, Issue.5 PART 1
, pp. 403-414
-
-
Pasquier, F.1
Boulogne, A.2
Leys, D.3
Fontaine, P.4
-
18
-
-
31644446183
-
Cholesterol and Alzheimer's disease - Is there a relation?
-
10.1016/j.mad.2005.09.020 16332384 10.1016/j.mad.2005.09.020 1:CAS:528:DC%2BD28XhtFWisr0%3D
-
Sjogren M, Mielke M, Gustafson D, Zandi P, Skoog I (2006) Cholesterol and Alzheimer's disease - is there a relation? Mech Ageing Dev 127(2):138-147. doi: 10.1016/j.mad.2005.09.020
-
(2006)
Mech Ageing Dev
, vol.127
, Issue.2
, pp. 138-147
-
-
Sjogren, M.1
Mielke, M.2
Gustafson, D.3
Zandi, P.4
Skoog, I.5
-
19
-
-
77955957056
-
Links between ApoE, brain cholesterol metabolism, tau and amyloid beta-peptide in patients with cognitive impairment
-
10.1042/BST0381021 20658997 1:CAS:528:DC%2BC3cXptlylsL4%3D 10.1042/BST0381021
-
Leoni V, Solomon A, Kivipelto M (2010) Links between ApoE, brain cholesterol metabolism, tau and amyloid beta-peptide in patients with cognitive impairment. Biochem Soc Trans 38(4):1021-1025. doi: 10.1042/BST0381021
-
(2010)
Biochem Soc Trans
, vol.38
, Issue.4
, pp. 1021-1025
-
-
Leoni, V.1
Solomon, A.2
Kivipelto, M.3
-
20
-
-
73649112749
-
Dysregulation of insulin signaling, glucose transporters, O-GlcNAcylation, and phosphorylation of tau and neurofilaments in the brain: Implication for Alzheimer's disease
-
10.2353/ajpath.2009.090157 19815707 1:CAS:528:DC%2BC3cXhslSjtb0%3D 10.2353/ajpath.2009.090157
-
Deng Y, Li B, Liu Y, Iqbal K, Grundke-Iqbal I, Gong CX (2009) Dysregulation of insulin signaling, glucose transporters, O-GlcNAcylation, and phosphorylation of tau and neurofilaments in the brain: Implication for Alzheimer's disease. Am J Pathol 175(5):2089-2098. doi: 10.2353/ajpath.2009. 090157
-
(2009)
Am J Pathol
, vol.175
, Issue.5
, pp. 2089-2098
-
-
Deng, Y.1
Li, B.2
Liu, Y.3
Iqbal, K.4
Grundke-Iqbal, I.5
Gong, C.X.6
-
21
-
-
0024545260
-
Cerebral excess release of neurotransmitter amino acids subsequent to reduced cerebral glucose metabolism in early-onset dementia of Alzheimer type
-
2926384 1:STN:280:DyaL1M7nslSrsw%3D%3D 10.1007/BF01258634
-
Hoyer S, Nitsch R (1989) Cerebral excess release of neurotransmitter amino acids subsequent to reduced cerebral glucose metabolism in early-onset dementia of Alzheimer type. J Neural Transm 75(3):227-232
-
(1989)
J Neural Transm
, vol.75
, Issue.3
, pp. 227-232
-
-
Hoyer, S.1
Nitsch, R.2
-
22
-
-
33847793387
-
Is Glucagon-like peptide-1, an agent treating diabetes, a new hope for Alzheimer's disease?
-
17592527 10.1007/s12264-007-0009-y
-
Li L (2007) Is Glucagon-like peptide-1, an agent treating diabetes, a new hope for Alzheimer's disease? Neurosci Bull 23(1):58-65
-
(2007)
Neurosci Bull
, vol.23
, Issue.1
, pp. 58-65
-
-
Li, L.1
-
23
-
-
0036966876
-
The glucagon-like peptides: A new genre in therapeutic targets for intervention in Alzheimer's disease
-
12515900 1:CAS:528:DC%2BD38Xpsl2ksb8%3D
-
Perry T, Greig NH (2002) The glucagon-like peptides: a new genre in therapeutic targets for intervention in Alzheimer's disease. J Alzheimers Dis 4(6):487-496
-
(2002)
J Alzheimers Dis
, vol.4
, Issue.6
, pp. 487-496
-
-
Perry, T.1
Greig, N.H.2
-
24
-
-
36448936053
-
Common pathological processes in Alzheimer disease and type 2 diabetes: A review
-
10.1016/j.brainresrev.2007.09.001 17920690 1:CAS:528:DC%2BD2sXhsVSrsr%2FK 10.1016/j.brainresrev.2007.09.001
-
Li L, Holscher C (2007) Common pathological processes in Alzheimer disease and type 2 diabetes: a review. Brain Res Rev 56(2):384-402. doi: 10.1016/j.brainresrev.2007.09.001
-
(2007)
Brain Res Rev
, vol.56
, Issue.2
, pp. 384-402
-
-
Li, L.1
Holscher, C.2
-
25
-
-
77950866465
-
Epigenetic regulation in the pathophysiology of Alzheimer's disease
-
10.1016/j.pneurobio.2010.01.002 20097254 1:CAS:528:DC%2BC3cXjs1ejsb8%3D 10.1016/j.pneurobio.2010.01.002
-
Chouliaras L, Rutten BP, Kenis G, Peerbooms O, Visser PJ, Verhey F, van Os J, Steinbusch HW, van den Hove DL (2010) Epigenetic regulation in the pathophysiology of Alzheimer's disease. Prog Neurobiol 90(4):498-510. doi: 10.1016/j.pneurobio.2010.01.002
-
(2010)
Prog Neurobiol
, vol.90
, Issue.4
, pp. 498-510
-
-
Chouliaras, L.1
Rutten, B.P.2
Kenis, G.3
Peerbooms, O.4
Visser, P.J.5
Verhey, F.6
Van Os, J.7
Steinbusch, H.W.8
Van Den Hove, D.L.9
-
26
-
-
73249133400
-
Epigenetics: A molecular link between environmental factors and type 2 diabetes
-
10.2337/db09-1003 19940235 1:CAS:528:DC%2BD1MXhsFKlurbO 10.2337/db09-1003
-
Ling C, Groop L (2009) Epigenetics: a molecular link between environmental factors and type 2 diabetes. Diabetes 58(12):2718-2725. doi: 10.2337/db09-1003
-
(2009)
Diabetes
, vol.58
, Issue.12
, pp. 2718-2725
-
-
Ling, C.1
Groop, L.2
-
27
-
-
0042023711
-
Alzheimer disease in the US population: Prevalence estimates using the 2000 census
-
10.1001/archneur.60.8.1119 12925369 10.1001/archneur.60.8.1119
-
Hebert LE, Scherr PA, Bienias JL, Bennett DA, Evans DA (2003) Alzheimer disease in the US population: prevalence estimates using the 2000 census. Arch Neurol 60(8):1119-1122. doi: 10.1001/archneur.60.8.1119
-
(2003)
Arch Neurol
, vol.60
, Issue.8
, pp. 1119-1122
-
-
Hebert, L.E.1
Scherr, P.A.2
Bienias, J.L.3
Bennett, D.A.4
Evans, D.A.5
-
28
-
-
84860618647
-
The growing burden of Alzheimer's disease
-
Lopez OL (2011) The growing burden of Alzheimer's disease. Am J Manage Care 17(Suppl 13):S339-S345
-
(2011)
Am J Manage Care
, vol.17
, Issue.SUPPL. 13
-
-
Lopez, O.L.1
-
29
-
-
33845472699
-
The burden and treatment of diabetes in elderly individuals in the U.S
-
10.2337/dc06-1058 17065677 10.2337/dc06-1058
-
Selvin E, Coresh J, Brancati FL (2006) The burden and treatment of diabetes in elderly individuals in the U.S. Diabetes Care 29(11):2415-2419. doi: 10.2337/dc06-1058
-
(2006)
Diabetes Care
, vol.29
, Issue.11
, pp. 2415-2419
-
-
Selvin, E.1
Coresh, J.2
Brancati, F.L.3
-
30
-
-
67650439330
-
Caloric restriction delays disease onset and mortality in rhesus monkeys
-
10.1126/science.1173635 19590001 1:CAS:528:DC%2BD1MXos1SrtL0%3D 10.1126/science.1173635
-
Colman RJ, Anderson RM, Johnson SC, Kastman EK, Kosmatka KJ, Beasley TM, Allison DB, Cruzen C, Simmons HA, Kemnitz JW, Weindruch R (2009) Caloric restriction delays disease onset and mortality in rhesus monkeys. Science 325(5937):201-204. doi: 10.1126/science.1173635
-
(2009)
Science
, vol.325
, Issue.5937
, pp. 201-204
-
-
Colman, R.J.1
Anderson, R.M.2
Johnson, S.C.3
Kastman, E.K.4
Kosmatka, K.J.5
Beasley, T.M.6
Allison, D.B.7
Cruzen, C.8
Simmons, H.A.9
Kemnitz, J.W.10
Weindruch, R.11
-
31
-
-
80054958546
-
The potential role of epigenetic responses to diet in ageing
-
10.1017/S0029665111000851 21781363 10.1017/S0029665111000851
-
Ford D, Ions LJ, Alatawi F, Wakeling LA (2011) The potential role of epigenetic responses to diet in ageing. Proc Nutr Soc 70(3):374-384. doi: 10.1017/S0029665111000851
-
(2011)
Proc Nutr Soc
, vol.70
, Issue.3
, pp. 374-384
-
-
Ford, D.1
Ions, L.J.2
Alatawi, F.3
Wakeling, L.A.4
-
32
-
-
70449864788
-
Effects of caloric restriction on cardiovascular aging in non-human primates and humans
-
10.1016/j.cger.2009.07.001 19944270 10.1016/j.cger.2009.07.001
-
Cruzen C, Colman RJ (2009) Effects of caloric restriction on cardiovascular aging in non-human primates and humans. Clin Geriatr Med 25(4):733-743. doi: 10.1016/j.cger.2009.07.001
-
(2009)
Clin Geriatr Med
, vol.25
, Issue.4
, pp. 733-743
-
-
Cruzen, C.1
Colman, R.J.2
-
33
-
-
84155172896
-
Caloric restriction and chronic inflammatory diseases
-
10.1111/j.1601-0825.2011.01830.x 21749581 1:STN:280: DC%2BC38%2FosVentg%3D%3D 10.1111/j.1601-0825.2011.01830.x
-
Gonzalez O, Tobia C, Ebersole J, Novak MJ (2012) Caloric restriction and chronic inflammatory diseases. Oral Dis 18(1):16-31. doi: 10.1111/j.1601-0825. 2011.01830.x
-
(2012)
Oral Dis
, vol.18
, Issue.1
, pp. 16-31
-
-
Gonzalez, O.1
Tobia, C.2
Ebersole, J.3
Novak, M.J.4
-
34
-
-
84859329846
-
Respiratory complications of obesity
-
22372230
-
Mandal S, Hart N (2012) Respiratory complications of obesity. Clin Med 12(1):75-78
-
(2012)
Clin Med
, vol.12
, Issue.1
, pp. 75-78
-
-
Mandal, S.1
Hart, N.2
-
35
-
-
80051748943
-
Insulin resistance: The link between obesity and cardiovascular disease
-
10.1016/j.mcna.2011.06.002 21855697 1:CAS:528:DC%2BC3MXhtVGmtrfM 10.1016/j.mcna.2011.06.002
-
Reaven GM (2011) Insulin resistance: the link between obesity and cardiovascular disease. Med Clin North Am 95(5):875-892. doi: 10.1016/j.mcna.2011.06.002
-
(2011)
Med Clin North Am
, vol.95
, Issue.5
, pp. 875-892
-
-
Reaven, G.M.1
-
36
-
-
79954996833
-
Body mass index in midlife and late-life as a risk factor for dementia: A meta-analysis of prospective studies
-
10.1111/j.1467-789X.2010.00825.x 21348917 1:STN:280: DC%2BC3MvksVGjsw%3D%3D 10.1111/j.1467-789X.2010.00825.x
-
Anstey KJ, Cherbuin N, Budge M, Young J (2011) Body mass index in midlife and late-life as a risk factor for dementia: a meta-analysis of prospective studies. Obes Rev 12(5):e426-e437. doi: 10.1111/j.1467-789X.2010.00825.x
-
(2011)
Obes Rev
, vol.12
, Issue.5
-
-
Anstey, K.J.1
Cherbuin, N.2
Budge, M.3
Young, J.4
-
37
-
-
84857437426
-
Minireview: Epigenetics of obesity and diabetes in humans
-
10.1210/en.2011-1759 22253427 1:CAS:528:DC%2BC38Xjs1antrs%3D 10.1210/en.2011-1759
-
Slomko H, Heo HJ, Einstein FH (2012) Minireview: epigenetics of obesity and diabetes in humans. Endocrinology 153(3):1025-1030. doi: 10.1210/en.2011-1759
-
(2012)
Endocrinology
, vol.153
, Issue.3
, pp. 1025-1030
-
-
Slomko, H.1
Heo, H.J.2
Einstein, F.H.3
-
38
-
-
34147101131
-
Relation of obesity to cognitive function: Importance of central obesity and synergistic influence of concomitant hypertension. The Framingham Heart Study
-
17430232 1:CAS:528:DC%2BD2sXksVWktrg%3D 10.2174/156720507780362263
-
Wolf PA, Beiser A, Elias MF, Au R, Vasan RS, Seshadri S (2007) Relation of obesity to cognitive function: importance of central obesity and synergistic influence of concomitant hypertension. The Framingham Heart Study. Curr Alzheimer Res 4(2):111-116
-
(2007)
Curr Alzheimer Res
, vol.4
, Issue.2
, pp. 111-116
-
-
Wolf, P.A.1
Beiser, A.2
Elias, M.F.3
Au, R.4
Vasan, R.S.5
Seshadri, S.6
-
39
-
-
42249094013
-
Adiposity, hyperinsulinemia, diabetes and Alzheimer's disease: An epidemiological perspective
-
10.1016/j.ejphar.2008.02.048 18384771 1:CAS:528:DC%2BD1cXlsF2qu7Y%3D 10.1016/j.ejphar.2008.02.048
-
Luchsinger JA (2008) Adiposity, hyperinsulinemia, diabetes and Alzheimer's disease: an epidemiological perspective. Eur J Pharmacol 585(1):119-129. doi: 10.1016/j.ejphar.2008.02.048
-
(2008)
Eur J Pharmacol
, vol.585
, Issue.1
, pp. 119-129
-
-
Luchsinger, J.A.1
-
40
-
-
79960259800
-
Type 2 diabetes and late-onset Alzheimer's disease
-
10.1159/000324134 21757907 1:STN:280:DC%2BC3MjkvFajtA%3D%3D 10.1159/000324134
-
Cheng D, Noble J, Tang MX, Schupf N, Mayeux R, Luchsinger JA (2011) Type 2 diabetes and late-onset Alzheimer's disease. Dement Geriatr Cogn Disord 31(6):424-430. doi: 10.1159/000324134
-
(2011)
Dement Geriatr Cogn Disord
, vol.31
, Issue.6
, pp. 424-430
-
-
Cheng, D.1
Noble, J.2
Tang, M.X.3
Schupf, N.4
Mayeux, R.5
Luchsinger, J.A.6
-
41
-
-
83755184174
-
Diabetes mellitus and cognitive decline
-
10.1007/s10354-011-0003-x 21792530 10.1007/s10354-011-0003-x
-
Iglseder B (2011) Diabetes mellitus and cognitive decline. Wien Med Wochenschr 161(21-22):524-530. doi: 10.1007/s10354-011-0003-x
-
(2011)
Wien Med Wochenschr
, vol.161
, Issue.21-22
, pp. 524-530
-
-
Iglseder, B.1
-
42
-
-
80054959351
-
Dementia and other chronic diseases in older adults in Havana and Matanzas: The 10/66 study in Cuba
-
22143605
-
Llibre Jde J, Valhuerdi A, Calvo M, Garcia RM, Guerra M, Laucerique T, Lopez AM, Llibre JC, Noriega L, Sanchez IY, Porto R, Arencibia F, Marcheco B, Moreno C (2011) Dementia and other chronic diseases in older adults in Havana and Matanzas: the 10/66 study in Cuba. MEDICC rev 13(4):30-37
-
(2011)
MEDICC Rev
, vol.13
, Issue.4
, pp. 30-37
-
-
Llibre Jde, J.1
Valhuerdi, A.2
Calvo, M.3
Garcia, R.M.4
Guerra, M.5
Laucerique, T.6
Lopez, A.M.7
Llibre, J.C.8
Noriega, L.9
Sanchez, I.Y.10
Porto, R.11
Arencibia, F.12
Marcheco, B.13
Moreno, C.14
-
43
-
-
84855918317
-
Risk factors of dementia in North India: A case-control study
-
10.1080/13607863.2011.583632 21714688 10.1080/13607863.2011.583632
-
Tripathi M, Vibha D, Gupta P, Bhatia R, Srivastava MV, Vivekanandhan S, Bhushan Singh M, Prasad K, Dergalust S, Mendez MF (2012) Risk factors of dementia in North India: a case-control study. Aging Ment Health 16(2):228-235. doi: 10.1080/13607863.2011.583632
-
(2012)
Aging Ment Health
, vol.16
, Issue.2
, pp. 228-235
-
-
Tripathi, M.1
Vibha, D.2
Gupta, P.3
Bhatia, R.4
Srivastava, M.V.5
Vivekanandhan, S.6
Bhushan Singh, M.7
Prasad, K.8
Dergalust, S.9
Mendez, M.F.10
-
44
-
-
84860289818
-
Can Alzheimer disease be a form of type 3 diabetes?
-
10.1089/rej.2011.1289 22533436 1:CAS:528:DC%2BC38Xmt1Glsbc%3D 10.1089/rej.2011.1289
-
Accardi G, Caruso C, Colonna-Romano G, Camarda C, Monastero R, Candore G (2012) Can Alzheimer disease be a form of type 3 diabetes? Rejuvenation Res 15(2):217-221. doi: 10.1089/rej.2011.1289
-
(2012)
Rejuvenation Res
, vol.15
, Issue.2
, pp. 217-221
-
-
Accardi, G.1
Caruso, C.2
Colonna-Romano, G.3
Camarda, C.4
Monastero, R.5
Candore, G.6
-
45
-
-
68949089312
-
Alzheimer's disease is type 3 diabetes-evidence reviewed
-
de la Monte SM, Wands JR (2008) Alzheimer's disease is type 3 diabetes-evidence reviewed. J Diabetes Sci Tech 2(6):1101-1113
-
(2008)
J Diabetes Sci Tech
, vol.2
, Issue.6
, pp. 1101-1113
-
-
De La Monte, S.M.1
Wands, J.R.2
-
46
-
-
0037264120
-
Unfolding the role of protein misfolding in neurodegenerative diseases
-
10.1038/nrn1007 12511861 1:CAS:528:DC%2BD3sXptlY%3D 10.1038/nrn1007
-
Soto C (2003) Unfolding the role of protein misfolding in neurodegenerative diseases. Nat Rev Neurosci 4(1):49-60. doi: 10.1038/nrn1007
-
(2003)
Nat Rev Neurosci
, vol.4
, Issue.1
, pp. 49-60
-
-
Soto, C.1
-
47
-
-
84859755505
-
Alzheimer's disease and the amyloid cascade hypothesis: A critical review
-
10.1155/2012/369808 22506132
-
Reitz C (2012) Alzheimer's disease and the amyloid cascade hypothesis: a critical review. Int J Alzheimers Dis 2012:369808. doi: 10.1155/2012/369808
-
(2012)
Int J Alzheimers Dis
, vol.2012
, pp. 369808
-
-
Reitz, C.1
-
48
-
-
78651245383
-
Stoichiometry and affinity of the human serum albumin-Alzheimer's Abeta peptide interactions
-
10.1016/j.bpj.2010.11.037 21190670 1:CAS:528:DC%2BC3cXhs1Wkt7vM 10.1016/j.bpj.2010.11.037
-
Milojevic J, Melacini G (2011) Stoichiometry and affinity of the human serum albumin-Alzheimer's Abeta peptide interactions. Biophys J 100(1):183-192. doi: 10.1016/j.bpj.2010.11.037
-
(2011)
Biophys J
, vol.100
, Issue.1
, pp. 183-192
-
-
Milojevic, J.1
Melacini, G.2
-
49
-
-
49149124343
-
Amyloid-beta protein dimers isolated directly from Alzheimer's brains impair synaptic plasticity and memory
-
10.1038/nm1782 18568035 1:CAS:528:DC%2BD1cXptlKltb0%3D 10.1038/nm1782
-
Shankar GM, Li S, Mehta TH, Garcia-Munoz A, Shepardson NE, Smith I, Brett FM, Farrell MA, Rowan MJ, Lemere CA, Regan CM, Walsh DM, Sabatini BL, Selkoe DJ (2008) Amyloid-beta protein dimers isolated directly from Alzheimer's brains impair synaptic plasticity and memory. Nat Med 14(8):837-842. doi: 10.1038/nm1782
-
(2008)
Nat Med
, vol.14
, Issue.8
, pp. 837-842
-
-
Shankar, G.M.1
Li, S.2
Mehta, T.H.3
Garcia-Munoz, A.4
Shepardson, N.E.5
Smith, I.6
Brett, F.M.7
Farrell, M.A.8
Rowan, M.J.9
Lemere, C.A.10
Regan, C.M.11
Walsh, D.M.12
Sabatini, B.L.13
Selkoe, D.J.14
-
50
-
-
80155209561
-
Misfolded proteins in Alzheimer's disease and type II diabetes
-
10.1039/c1cs15112f 21818468 1:CAS:528:DC%2BC38XhvFKisw%3D%3D 10.1039/c1cs15112f
-
DeToma AS, Salamekh S, Ramamoorthy A, Lim MH (2012) Misfolded proteins in Alzheimer's disease and type II diabetes. Chem Soc Rev 41(2):608-621. doi: 10.1039/c1cs15112f
-
(2012)
Chem Soc Rev
, vol.41
, Issue.2
, pp. 608-621
-
-
Detoma, A.S.1
Salamekh, S.2
Ramamoorthy, A.3
Lim, M.H.4
-
51
-
-
33847662852
-
Soluble protein oligomers in neurodegeneration: Lessons from the Alzheimer's amyloid beta-peptide
-
10.1038/nrm2101 17245412 1:CAS:528:DC%2BD2sXotFKmtw%3D%3D 10.1038/nrm2101
-
Haass C, Selkoe DJ (2007) Soluble protein oligomers in neurodegeneration: lessons from the Alzheimer's amyloid beta-peptide. Nat Rev Mol Cell Biol 8(2):101-112. doi: 10.1038/nrm2101
-
(2007)
Nat Rev Mol Cell Biol
, vol.8
, Issue.2
, pp. 101-112
-
-
Haass, C.1
Selkoe, D.J.2
-
52
-
-
84857788978
-
Insulin signaling, glucose metabolism and mitochondria: Major players in Alzheimer's disease and diabetes interrelation
-
10.1016/j.brainres.2011.12.063 22290178 1:CAS:528:DC%2BC38XivVentrs%3D 10.1016/j.brainres.2011.12.063
-
Correia SC, Santos RX, Carvalho C, Cardoso S, Candeias E, Santos MS, Oliveira CR, Moreira PI (2012) Insulin signaling, glucose metabolism and mitochondria: major players in Alzheimer's disease and diabetes interrelation. Brain Res 1441:64-78. doi: 10.1016/j.brainres.2011.12.063
-
(2012)
Brain Res
, vol.1441
, pp. 64-78
-
-
Correia, S.C.1
Santos, R.X.2
Carvalho, C.3
Cardoso, S.4
Candeias, E.5
Santos, M.S.6
Oliveira, C.R.7
Moreira, P.I.8
-
53
-
-
36749033116
-
Peptide conformation and supramolecular organization in amylin fibrils: Constraints from solid-state NMR
-
10.1021/bi701427q 17979302 1:CAS:528:DC%2BD2sXht1CktbzK 10.1021/bi701427q
-
Luca S, Yau WM, Leapman R, Tycko R (2007) Peptide conformation and supramolecular organization in amylin fibrils: constraints from solid-state NMR. Biochemistry 46(47):13505-13522. doi: 10.1021/bi701427q
-
(2007)
Biochemistry
, vol.46
, Issue.47
, pp. 13505-13522
-
-
Luca, S.1
Yau, W.M.2
Leapman, R.3
Tycko, R.4
-
54
-
-
33845328809
-
Pancreatic signals controlling food intake; Insulin, glucagon and amylin
-
10.1098/rstb.2006.1858 1:CAS:528:DC%2BD28XhtVygtL7I 10.1098/rstb.2006. 1858
-
Woods SC, Lutz TA, Geary N, Langhans W (2006) Pancreatic signals controlling food intake; insulin, glucagon and amylin. Philos Trans R Soc B Biol Sci 361(1471):1219-1235. doi: 10.1098/rstb.2006.1858
-
(2006)
Philos Trans R Soc B Biol Sci
, vol.361
, Issue.1471
, pp. 1219-1235
-
-
Woods, S.C.1
Lutz, T.A.2
Geary, N.3
Langhans, W.4
-
55
-
-
43549100675
-
Islet amyloid in type 2 diabetes, and the toxic oligomer hypothesis
-
10.1210/er.2007-0037 18314421 1:CAS:528:DC%2BD1cXntV2lsbo%3D 10.1210/er.2007-0037
-
Haataja L, Gurlo T, Huang CJ, Butler PC (2008) Islet amyloid in type 2 diabetes, and the toxic oligomer hypothesis. Endocr Rev 29(3):303-316. doi: 10.1210/er.2007-0037
-
(2008)
Endocr Rev
, vol.29
, Issue.3
, pp. 303-316
-
-
Haataja, L.1
Gurlo, T.2
Huang, C.J.3
Butler, P.C.4
-
56
-
-
61449123871
-
Oxidative stress is induced by islet amyloid formation and time-dependently mediates amyloid-induced beta cell apoptosis
-
10.1007/s00125-008-1255-x 19148619 1:CAS:528:DC%2BD1MXisFSisrs%3D 10.1007/s00125-008-1255-x
-
Zraika S, Hull RL, Udayasankar J, Aston-Mourney K, Subramanian SL, Kisilevsky R, Szarek WA, Kahn SE (2009) Oxidative stress is induced by islet amyloid formation and time-dependently mediates amyloid-induced beta cell apoptosis. Diabetologia 52(4):626-635. doi: 10.1007/s00125-008-1255-x
-
(2009)
Diabetologia
, vol.52
, Issue.4
, pp. 626-635
-
-
Zraika, S.1
Hull, R.L.2
Udayasankar, J.3
Aston-Mourney, K.4
Subramanian, S.L.5
Kisilevsky, R.6
Szarek, W.A.7
Kahn, S.E.8
-
57
-
-
0842309993
-
Increased risk of type 2 diabetes in Alzheimer disease
-
14747300 1:CAS:528:DC%2BD2cXhtlWgsr8%3D 10.2337/diabetes.53.2.474
-
Janson J, Laedtke T, Parisi JE, O'Brien P, Petersen RC, Butler PC (2004) Increased risk of type 2 diabetes in Alzheimer disease. Diabetes 53(2):474-481
-
(2004)
Diabetes
, vol.53
, Issue.2
, pp. 474-481
-
-
Janson, J.1
Laedtke, T.2
Parisi, J.E.3
O'Brien, P.4
Petersen, R.C.5
Butler, P.C.6
-
58
-
-
84861547526
-
Amyloid beta (Abeta) peptide directly activates amylin-3 receptor subtype by triggering multiple intracellular signaling pathways
-
10.1074/jbc.M111.331181 22500019 1:CAS:528:DC%2BC38XnsF2ms7Y%3D 10.1074/jbc.M111.331181
-
Fu W, Ruangkittisakul A, MacTavish D, Shi JY, Ballanyi K, Jhamandas JH (2012) Amyloid beta (Abeta) peptide directly activates amylin-3 receptor subtype by triggering multiple intracellular signaling pathways. J Biol Chem 287(22):18820-18830. doi: 10.1074/jbc.M111.331181
-
(2012)
J Biol Chem
, vol.287
, Issue.22
, pp. 18820-18830
-
-
Fu, W.1
Ruangkittisakul, A.2
MacTavish, D.3
Shi, J.Y.4
Ballanyi, K.5
Jhamandas, J.H.6
-
59
-
-
84863801673
-
Generic inhibition of amyloidogenic proteins by two naphthoquinone- tryptophan hybrid molecules
-
10.1002/prot.24080 22488522 1:CAS:528:DC%2BC38XnsFyitr4%3D
-
Scherzer-Attali R, Shaltiel-Karyo R, Adalist YH, Segal D, Gazit E (2012) Generic inhibition of amyloidogenic proteins by two naphthoquinone-tryptophan hybrid molecules. Proteins 80(8):1962-1973. doi: 10.1002/prot.24080
-
(2012)
Proteins
, vol.80
, Issue.8
, pp. 1962-1973
-
-
Scherzer-Attali, R.1
Shaltiel-Karyo, R.2
Adalist, Y.H.3
Segal, D.4
Gazit, E.5
-
60
-
-
84863980717
-
Nucleobindin 1 caps human islet amyloid polypeptide protofibrils to prevent amyloid fibril formation
-
10.1016/j.jmb.2012.04.017 22542527 1:CAS:528:DC%2BC38Xns1Wmu7w%3D 10.1016/j.jmb.2012.04.017
-
Gupta R, Kapoor N, Raleigh DP, Sakmar TP (2012) Nucleobindin 1 caps human islet amyloid polypeptide protofibrils to prevent amyloid fibril formation. J Mol Biol 421(2-3):378-389. doi: 10.1016/j.jmb.2012.04.017
-
(2012)
J Mol Biol
, vol.421
, Issue.2-3
, pp. 378-389
-
-
Gupta, R.1
Kapoor, N.2
Raleigh, D.P.3
Sakmar, T.P.4
-
61
-
-
33845244172
-
Pathophysiology of insulin resistance
-
10.1016/j.beem.2006.09.007 17161338 1:CAS:528:DC%2BD28Xht12ksb%2FO 10.1016/j.beem.2006.09.007
-
Sesti G (2006) Pathophysiology of insulin resistance. Best Pract Res Clin Endocrinol Metab 20(4):665-679. doi: 10.1016/j.beem.2006.09.007
-
(2006)
Best Pract Res Clin Endocrinol Metab
, vol.20
, Issue.4
, pp. 665-679
-
-
Sesti, G.1
-
62
-
-
84872500787
-
Diabetes, insulin and cancer risk
-
10.4239/wjd.v3.i4.60 22532884 10.4239/wjd.v3.i4.60
-
Yang XL, Chan JC (2012) Diabetes, insulin and cancer risk. World J Diabetes 3(4):60-64. doi: 10.4239/wjd.v3.i4.60
-
(2012)
World J Diabetes
, vol.3
, Issue.4
, pp. 60-64
-
-
Yang, X.L.1
Chan, J.C.2
-
63
-
-
1842734659
-
The source of cerebral insulin
-
10.1016/j.ejphar.2004.02.040 15094069 1:CAS:528:DC%2BD2cXjt1ShsLs%3D 10.1016/j.ejphar.2004.02.040
-
Banks WA (2004) The source of cerebral insulin. Eur J Pharmacol 490(1-3):5-12. doi: 10.1016/j.ejphar.2004.02.040
-
(2004)
Eur J Pharmacol
, vol.490
, Issue.1-3
, pp. 5-12
-
-
Banks, W.A.1
-
64
-
-
79960555700
-
Possible implications of insulin resistance and glucose metabolism in Alzheimer's disease pathogenesis
-
10.1111/j.1582-4934.2011.01318.x 21435176 1:CAS:528:DC%2BC3MXht1ejt7jF 10.1111/j.1582-4934.2011.01318.x
-
Bosco D, Fava A, Plastino M, Montalcini T, Pujia A (2011) Possible implications of insulin resistance and glucose metabolism in Alzheimer's disease pathogenesis. J Cell Mol Med 15(9):1807-1821. doi: 10.1111/j.1582-4934.2011. 01318.x
-
(2011)
J Cell Mol Med
, vol.15
, Issue.9
, pp. 1807-1821
-
-
Bosco, D.1
Fava, A.2
Plastino, M.3
Montalcini, T.4
Pujia, A.5
-
65
-
-
79953242703
-
The role of insulin signaling in the development of beta-cell dysfunction and diabetes
-
10.4161/isl.1.2.9263 21099255 10.4161/isl.1.2.9263
-
Wang Q, Jin T (2009) The role of insulin signaling in the development of beta-cell dysfunction and diabetes. Islets 1(2):95-101. doi: 10.4161/isl.1.2.9263
-
(2009)
Islets
, vol.1
, Issue.2
, pp. 95-101
-
-
Wang, Q.1
Jin, T.2
-
66
-
-
84856354253
-
Sensing of glucose in the brain
-
10.1007/978-3-642-24716-3-12 22249819 1:CAS:528:DC%2BC38XhslCgu7%2FF 10.1007/978-3-642-24716-3-12
-
Thorens B (2012) Sensing of glucose in the brain. Handb Exp Pharmacol 209:277-294. doi: 10.1007/978-3-642-24716-3-12
-
(2012)
Handb Exp Pharmacol
, vol.209
, pp. 277-294
-
-
Thorens, B.1
-
67
-
-
84867766778
-
Insulin resistance, metabolic stress, and atherosclerosis
-
10.2741/S308
-
Pansuria M, Xi H, Li L, Yang XF, Wang H (2012) Insulin resistance, metabolic stress, and atherosclerosis. Front Biosci 4:916-931
-
(2012)
Front Biosci
, vol.4
, pp. 916-931
-
-
Pansuria, M.1
Xi, H.2
Li, L.3
Yang, X.F.4
Wang, H.5
-
68
-
-
63249092689
-
Insulin reduces cerebral ischemia/reperfusion injury in the hippocampus of diabetic rats: A role for glycogen synthase kinase-3beta
-
10.2337/db08-0691 18840784 1:CAS:528:DC%2BD1MXptVCntg%3D%3D 10.2337/db08-0691
-
Collino M, Aragno M, Castiglia S, Tomasinelli C, Thiemermann C, Boccuzzi G, Fantozzi R (2009) Insulin reduces cerebral ischemia/reperfusion injury in the hippocampus of diabetic rats: a role for glycogen synthase kinase-3beta. Diabetes 58(1):235-242. doi: 10.2337/db08-0691
-
(2009)
Diabetes
, vol.58
, Issue.1
, pp. 235-242
-
-
Collino, M.1
Aragno, M.2
Castiglia, S.3
Tomasinelli, C.4
Thiemermann, C.5
Boccuzzi, G.6
Fantozzi, R.7
-
69
-
-
84859718265
-
Demonstrated brain insulin resistance in Alzheimer's disease patients is associated with IGF-1 resistance, IRS-1 dysregulation, and cognitive decline
-
10.1172/JCI59903 22476197 1:CAS:528:DC%2BC38Xlt1egtbY%3D 10.1172/JCI59903
-
Talbot K, Wang HY, Kazi H, Han LY, Bakshi KP, Stucky A, Fuino RL, Kawaguchi KR, Samoyedny AJ, Wilson RS, Arvanitakis Z, Schneider JA, Wolf BA, Bennett DA, Trojanowski JQ, Arnold SE (2012) Demonstrated brain insulin resistance in Alzheimer's disease patients is associated with IGF-1 resistance, IRS-1 dysregulation, and cognitive decline. J Clin Investig 122(4):1316-1338. doi: 10.1172/JCI59903
-
(2012)
J Clin Investig
, vol.122
, Issue.4
, pp. 1316-1338
-
-
Talbot, K.1
Wang, H.Y.2
Kazi, H.3
Han, L.Y.4
Bakshi, K.P.5
Stucky, A.6
Fuino, R.L.7
Kawaguchi, K.R.8
Samoyedny, A.J.9
Wilson, R.S.10
Arvanitakis, Z.11
Schneider, J.A.12
Wolf, B.A.13
Bennett, D.A.14
Trojanowski, J.Q.15
Arnold, S.E.16
-
70
-
-
79956359796
-
A common pathogenic mechanism linking type-2 diabetes and Alzheimer's disease: Evidence from animal models
-
10.3988/jcn.2011.7.1.10 21519521 10.3988/jcn.2011.7.1.10
-
Park SA (2011) A common pathogenic mechanism linking type-2 diabetes and Alzheimer's disease: evidence from animal models. J Clin Neurol 7(1):10-18. doi: 10.3988/jcn.2011.7.1.10
-
(2011)
J Clin Neurol
, vol.7
, Issue.1
, pp. 10-18
-
-
Park, S.A.1
-
71
-
-
34347377319
-
Alzheimer-like changes in rat models of spontaneous diabetes
-
10.2337/db07-0171 17456849 1:CAS:528:DC%2BD2sXnvVWju70%3D 10.2337/db07-0171
-
Li ZG, Zhang W, Sima AA (2007) Alzheimer-like changes in rat models of spontaneous diabetes. Diabetes 56(7):1817-1824. doi: 10.2337/db07-0171
-
(2007)
Diabetes
, vol.56
, Issue.7
, pp. 1817-1824
-
-
Li, Z.G.1
Zhang, W.2
Sima, A.A.3
-
72
-
-
84857783229
-
Cognitive decline in STZ-3 v rats is largely due to dysfunctional insulin signalling through the dentate gyrus
-
10.1016/j.bbr.2012.01.034 22289199 1:CAS:528:DC%2BC38Xjs1antbg%3D 10.1016/j.bbr.2012.01.034
-
Shingo AS, Kanabayashi T, Murase T, Kito S (2012) Cognitive decline in STZ-3 V rats is largely due to dysfunctional insulin signalling through the dentate gyrus. Behav Brain Res 229(2):378-383. doi: 10.1016/j.bbr.2012.01.034
-
(2012)
Behav Brain Res
, vol.229
, Issue.2
, pp. 378-383
-
-
Shingo, A.S.1
Kanabayashi, T.2
Murase, T.3
Kito, S.4
-
73
-
-
80053463292
-
Central insulin and insulin-like growth factor-1 signaling: Implications for diabetes associated dementia
-
21916834 1:CAS:528:DC%2BC3MXht1Cjs7nN 10.2174/157339911797415594
-
Zemva J, Schubert M (2011) Central insulin and insulin-like growth factor-1 signaling: implications for diabetes associated dementia. Curr Diabetes Rev 7(5):356-366
-
(2011)
Curr Diabetes Rev
, vol.7
, Issue.5
, pp. 356-366
-
-
Zemva, J.1
Schubert, M.2
-
74
-
-
38049110692
-
Amyloid beta oligomers induce impairment of neuronal insulin receptors
-
10.1096/fj.06-7703com 17720802 1:CAS:528:DC%2BD1cXkslWntw%3D%3D 10.1096/fj.06-7703com
-
Zhao WQ, De Felice FG, Fernandez S, Chen H, Lambert MP, Quon MJ, Krafft GA, Klein WL (2008) Amyloid beta oligomers induce impairment of neuronal insulin receptors. FASEB J 22(1):246-260. doi: 10.1096/fj.06-7703com
-
(2008)
FASEB J
, vol.22
, Issue.1
, pp. 246-260
-
-
Zhao, W.Q.1
De Felice, F.G.2
Fernandez, S.3
Chen, H.4
Lambert, M.P.5
Quon, M.J.6
Krafft, G.A.7
Klein, W.L.8
-
75
-
-
0035871641
-
Stimulation of beta-amyloid precursor protein trafficking by insulin reduces intraneuronal beta-amyloid and requires mitogen-activated protein kinase signaling
-
11306609 1:CAS:528:DC%2BD3MXjtVWkurs%3D
-
Gasparini L, Gouras GK, Wang R, Gross RS, Beal MF, Greengard P, Xu H (2001) Stimulation of beta-amyloid precursor protein trafficking by insulin reduces intraneuronal beta-amyloid and requires mitogen-activated protein kinase signaling. J Neurosci 21(8):2561-2570
-
(2001)
J Neurosci
, vol.21
, Issue.8
, pp. 2561-2570
-
-
Gasparini, L.1
Gouras, G.K.2
Wang, R.3
Gross, R.S.4
Beal, M.F.5
Greengard, P.6
Xu, H.7
-
76
-
-
0346101885
-
Enhanced proteolysis of beta-amyloid in APP transgenic mice prevents plaque formation, secondary pathology, and premature death
-
14687544 1:CAS:528:DC%2BD2cXhtVGrtQ%3D%3D 10.1016/S0896-6273(03)00787-6
-
Leissring MA, Farris W, Chang AY, Walsh DM, Wu X, Sun X, Frosch MP, Selkoe DJ (2003) Enhanced proteolysis of beta-amyloid in APP transgenic mice prevents plaque formation, secondary pathology, and premature death. Neuron 40(6):1087-1093
-
(2003)
Neuron
, vol.40
, Issue.6
, pp. 1087-1093
-
-
Leissring, M.A.1
Farris, W.2
Chang, A.Y.3
Walsh, D.M.4
Wu, X.5
Sun, X.6
Frosch, M.P.7
Selkoe, D.J.8
-
77
-
-
70349567668
-
Cerebral proteolysis of amiloid-b peptide: Relevance of insulin-degrading enzyme in Alzheimer's disease
-
19770104 1:CAS:528:DC%2BD1MXhtlymtb7J
-
Leal MC, Fernandez Gamba A, Morelli L, Castano EM (2009) Cerebral proteolysis of amiloid-b peptide: relevance of insulin-degrading enzyme in Alzheimer's disease. Medicina 69(4):466-472
-
(2009)
Medicina
, vol.69
, Issue.4
, pp. 466-472
-
-
Leal, M.C.1
Fernandez Gamba, A.2
Morelli, L.3
Castano, E.M.4
-
78
-
-
78650637178
-
Amyloid-beta as a modulator of synaptic plasticity
-
10.3233/JAD-2010-101020 20847424 1:CAS:528:DC%2BC3cXhsFSqt7zE
-
Parihar MS, Brewer GJ (2010) Amyloid-beta as a modulator of synaptic plasticity. J Alzheimers Dis 22(3):741-763. doi: 10.3233/JAD-2010-101020
-
(2010)
J Alzheimers Dis
, vol.22
, Issue.3
, pp. 741-763
-
-
Parihar, M.S.1
Brewer, G.J.2
-
79
-
-
80052146396
-
Beyond the hormone: Insulin as an autoimmune target in type 1 diabetes
-
10.1210/er.2011-0010 21700723 1:CAS:528:DC%2BC3MXhsFSrsLnJ 10.1210/er.2011-0010
-
Brezar V, Carel JC, Boitard C, Mallone R (2011) Beyond the hormone: insulin as an autoimmune target in type 1 diabetes. Endocr Rev 32(5):623-669. doi: 10.1210/er.2011-0010
-
(2011)
Endocr Rev
, vol.32
, Issue.5
, pp. 623-669
-
-
Brezar, V.1
Carel, J.C.2
Boitard, C.3
Mallone, R.4
-
80
-
-
84858705863
-
Insulin receptors and downstream substrates associate with membrane microdomains after treatment with insulin or chromium(III) picolinate
-
10.1007/s12013-011-9326-x 22101510 1:CAS:528:DC%2BC38Xktlaksb8%3D 10.1007/s12013-011-9326-x
-
Al-Qatati A, Winter PW, Wolf-Ringwall AL, Chatterjee PB, Van Orden AK, Crans DC, Roess DA, Barisas BG (2012) Insulin receptors and downstream substrates associate with membrane microdomains after treatment with insulin or chromium(III) picolinate. Cell Biochem Biophys 62(3):441-450. doi: 10.1007/s12013-011-9326-x
-
(2012)
Cell Biochem Biophys
, vol.62
, Issue.3
, pp. 441-450
-
-
Al-Qatati, A.1
Winter, P.W.2
Wolf-Ringwall, A.L.3
Chatterjee, P.B.4
Van Orden, A.K.5
Crans, D.C.6
Roess, D.A.7
Barisas, B.G.8
-
81
-
-
34248180625
-
Differential activation of insulin receptor substrates 1 and 2 by insulin-like growth factor-activated insulin receptors
-
10.1128/MCB.01447-06 17325037 1:CAS:528:DC%2BD2sXltlansbs%3D 10.1128/MCB.01447-06
-
Denley A, Carroll JM, Brierley GV, Cosgrove L, Wallace J, Forbes B, Roberts CT Jr (2007) Differential activation of insulin receptor substrates 1 and 2 by insulin-like growth factor-activated insulin receptors. Mol Cell Biol 27(10):3569-3577. doi: 10.1128/MCB.01447-06
-
(2007)
Mol Cell Biol
, vol.27
, Issue.10
, pp. 3569-3577
-
-
Denley, A.1
Carroll, J.M.2
Brierley, G.V.3
Cosgrove, L.4
Wallace, J.5
Forbes, B.6
Roberts, Jr.C.T.7
-
82
-
-
84856166319
-
Altered REDD1, myostatin, and Akt/mTOR/FoxO/MAPK signaling in streptozotocin-induced diabetic muscle atrophy
-
10.1152/ajpendo.00398.2011 22068602 1:CAS:528:DC%2BC38XjsFKhu74%3D 10.1152/ajpendo.00398.2011
-
Hulmi JJ, Silvennoinen M, Lehti M, Kivela R, Kainulainen H (2012) Altered REDD1, myostatin, and Akt/mTOR/FoxO/MAPK signaling in streptozotocin-induced diabetic muscle atrophy. Am J Physiol Endocrinol Metab 302(3):E307-E315. doi: 10.1152/ajpendo.00398.2011
-
(2012)
Am J Physiol Endocrinol Metab
, vol.302
, Issue.3
-
-
Hulmi, J.J.1
Silvennoinen, M.2
Lehti, M.3
Kivela, R.4
Kainulainen, H.5
-
83
-
-
79959369893
-
Knockdown of insulin receptor substrate 1 reduces proliferation and downregulates Akt/mTOR and MAPK pathways in K562 cells
-
10.1016/j.bbamcr.2011.04.002 21569802 1:CAS:528:DC%2BC3MXotVeltb8%3D 10.1016/j.bbamcr.2011.04.002
-
Machado-Neto JA, Favaro P, Lazarini M, Costa FF, Olalla Saad ST, Traina F (2011) Knockdown of insulin receptor substrate 1 reduces proliferation and downregulates Akt/mTOR and MAPK pathways in K562 cells. Biochim Biophys Acta 1813(8):1404-1411. doi: 10.1016/j.bbamcr.2011.04.002
-
(2011)
Biochim Biophys Acta
, vol.1813
, Issue.8
, pp. 1404-1411
-
-
MacHado-Neto, J.A.1
Favaro, P.2
Lazarini, M.3
Costa, F.F.4
Olalla Saad, S.T.5
Traina, F.6
-
84
-
-
84868282388
-
Insulin in central nervous system: More than just a peripheral hormone
-
10.1155/2012/384017 22500228
-
Duarte AI, Moreira PI, Oliveira CR (2012) Insulin in central nervous system: more than just a peripheral hormone. J Aging Res 2012:384017. doi: 10.1155/2012/384017
-
(2012)
J Aging Res
, vol.2012
, pp. 384017
-
-
Duarte, A.I.1
Moreira, P.I.2
Oliveira, C.R.3
-
85
-
-
79953674220
-
Promiscuous affairs of PKB/AKT isoforms in metabolism
-
10.3109/13813455.2010.539236 21214427 1:CAS:528:DC%2BC3MXktFWisrc%3D 10.3109/13813455.2010.539236
-
Schultze SM, Jensen J, Hemmings BA, Tschopp O, Niessen M (2011) Promiscuous affairs of PKB/AKT isoforms in metabolism. Arch Physiol Biochem 117(2):70-77. doi: 10.3109/13813455.2010.539236
-
(2011)
Arch Physiol Biochem
, vol.117
, Issue.2
, pp. 70-77
-
-
Schultze, S.M.1
Jensen, J.2
Hemmings, B.A.3
Tschopp, O.4
Niessen, M.5
-
86
-
-
53649106357
-
Dissecting the role of the 3-phosphoinositide-dependent protein kinase-1 (PDK1) signalling pathways
-
10.4161/cc.7.19.6810
-
Bayascas JR (2008) Dissecting the role of the 3-phosphoinositide- dependent protein kinase-1 (PDK1) signalling pathways. Cell Cycle 19:2978-2982
-
(2008)
Cell Cycle
, vol.19
, pp. 2978-2982
-
-
Bayascas, J.R.1
-
87
-
-
2942685674
-
Epidermal growth factor and insulin inhibit cell death in pancreatic beta cells by activation of PI3-kinase/AKT signaling pathway under oxidative stress
-
10.1016/j.transproceed.2004.04.018 15194403 1:CAS:528: DC%2BD2cXkvV2gsrg%3D 10.1016/j.transproceed.2004.04.018
-
Maeda H, Rajesh KG, Maeda H, Suzuki R, Sasaguri S (2004) Epidermal growth factor and insulin inhibit cell death in pancreatic beta cells by activation of PI3-kinase/AKT signaling pathway under oxidative stress. Transplant Proc 36(4):1163-1165. doi: 10.1016/j.transproceed.2004.04.018
-
(2004)
Transplant Proc
, vol.36
, Issue.4
, pp. 1163-1165
-
-
Maeda, H.1
Rajesh, K.G.2
Maeda, H.3
Suzuki, R.4
Sasaguri, S.5
-
88
-
-
80052433997
-
Pathway to diabetes through attenuation of pancreatic beta cell glycosylation and glucose transport
-
10.1038/nm.2414 21841783 1:CAS:528:DC%2BC3MXhtVWmtbfM 10.1038/nm.2414
-
Ohtsubo K, Chen MZ, Olefsky JM, Marth JD (2011) Pathway to diabetes through attenuation of pancreatic beta cell glycosylation and glucose transport. Nat Med 17(9):1067-1075. doi: 10.1038/nm.2414
-
(2011)
Nat Med
, vol.17
, Issue.9
, pp. 1067-1075
-
-
Ohtsubo, K.1
Chen, M.Z.2
Olefsky, J.M.3
Marth, J.D.4
-
89
-
-
80455128548
-
Insulin resistance, hyperglycemia, and atherosclerosis
-
10.1016/j.cmet.2011.07.015 22055501 1:CAS:528:DC%2BC3MXhsVaqtLfK 10.1016/j.cmet.2011.07.015
-
Bornfeldt KE, Tabas I (2011) Insulin resistance, hyperglycemia, and atherosclerosis. Cell Metab 14(5):575-585. doi: 10.1016/j.cmet.2011.07.015
-
(2011)
Cell Metab
, vol.14
, Issue.5
, pp. 575-585
-
-
Bornfeldt, K.E.1
Tabas, I.2
-
90
-
-
78751644241
-
Dysregulation of glycogen synthase kinase-3 in skeletal muscle and the etiology of insulin resistance and type 2 diabetes
-
20594161 1:CAS:528:DC%2BC3cXht1CjsL%2FL 10.2174/157339910793360888
-
Henriksen EJ (2010) Dysregulation of glycogen synthase kinase-3 in skeletal muscle and the etiology of insulin resistance and type 2 diabetes. Curr Diabetes Rev 6(5):285-293
-
(2010)
Curr Diabetes Rev
, vol.6
, Issue.5
, pp. 285-293
-
-
Henriksen, E.J.1
-
91
-
-
80052678652
-
Molecular mechanisms of insulin resistance in type 2 diabetes mellitus
-
10.4239/wjd.v1.i3.68 21537430 10.4239/wjd.v1.i3.68
-
Saini V (2010) Molecular mechanisms of insulin resistance in type 2 diabetes mellitus. World J Diabetes 1(3):68-75. doi: 10.4239/wjd.v1.i3.68
-
(2010)
World J Diabetes
, vol.1
, Issue.3
, pp. 68-75
-
-
Saini, V.1
-
92
-
-
84857604015
-
Changes in cognitive function in patients with diabetes mellitus
-
10.1556/OH.2012.29319 22348847 10.1556/OH.2012.29319
-
Szeman B, Nagy G, Varga T, Veres-Szekely A, Sasvari M, Fitala D, Szollosi A, Katonai R, Kotyuk E, Somogyi A (2012) Changes in cognitive function in patients with diabetes mellitus. Orv Hetil 153(9):323-329. doi: 10.1556/OH.2012.29319
-
(2012)
Orv Hetil
, vol.153
, Issue.9
, pp. 323-329
-
-
Szeman, B.1
Nagy, G.2
Varga, T.3
Veres-Szekely, A.4
Sasvari, M.5
Fitala, D.6
Szollosi, A.7
Katonai, R.8
Kotyuk, E.9
Somogyi, A.10
-
93
-
-
70349672704
-
Neuronal IGF-1 resistance reduces Abeta accumulation and protects against premature death in a model of Alzheimer's disease
-
10.1096/fj.09-132043 19487308 1:CAS:528:DC%2BD1MXht1GjtLnL 10.1096/fj.09-132043
-
Freude S, Hettich MM, Schumann C, Stohr O, Koch L, Kohler C, Udelhoven M, Leeser U, Muller M, Kubota N, Kadowaki T, Krone W, Schroder H, Bruning JC, Schubert M (2009) Neuronal IGF-1 resistance reduces Abeta accumulation and protects against premature death in a model of Alzheimer's disease. FASEB J 23(10):3315-3324. doi: 10.1096/fj.09-132043
-
(2009)
FASEB J
, vol.23
, Issue.10
, pp. 3315-3324
-
-
Freude, S.1
Hettich, M.M.2
Schumann, C.3
Stohr, O.4
Koch, L.5
Kohler, C.6
Udelhoven, M.7
Leeser, U.8
Muller, M.9
Kubota, N.10
Kadowaki, T.11
Krone, W.12
Schroder, H.13
Bruning, J.C.14
Schubert, M.15
-
94
-
-
67649224051
-
Deletion of Irs2 reduces amyloid deposition and rescues behavioural deficits in APP transgenic mice
-
10.1016/j.bbrc.2009.06.032 19523444 1:CAS:528:DC%2BD1MXnvVansr4%3D 10.1016/j.bbrc.2009.06.032
-
Killick R, Scales G, Leroy K, Causevic M, Hooper C, Irvine EE, Choudhury AI, Drinkwater L, Kerr F, Al-Qassab H, Stephenson J, Yilmaz Z, Giese KP, Brion JP, Withers DJ, Lovestone S (2009) Deletion of Irs2 reduces amyloid deposition and rescues behavioural deficits in APP transgenic mice. Biochem Biophys Res Commun 386(1):257-262. doi: 10.1016/j.bbrc.2009.06.032
-
(2009)
Biochem Biophys Res Commun
, vol.386
, Issue.1
, pp. 257-262
-
-
Killick, R.1
Scales, G.2
Leroy, K.3
Causevic, M.4
Hooper, C.5
Irvine, E.E.6
Choudhury, A.I.7
Drinkwater, L.8
Kerr, F.9
Al-Qassab, H.10
Stephenson, J.11
Yilmaz, Z.12
Giese, K.P.13
Brion, J.P.14
Withers, D.J.15
Lovestone, S.16
-
95
-
-
31044446941
-
Irs1 and Irs2 signaling is essential for hepatic glucose homeostasis and systemic growth
-
10.1172/JCI25735 16374520 1:CAS:528:DC%2BD28XjslOhsg%3D%3D 10.1172/JCI25735
-
Dong X, Park S, Lin X, Copps K, Yi X, White MF (2006) Irs1 and Irs2 signaling is essential for hepatic glucose homeostasis and systemic growth. J Clin Investig 116(1):101-114. doi: 10.1172/JCI25735
-
(2006)
J Clin Investig
, vol.116
, Issue.1
, pp. 101-114
-
-
Dong, X.1
Park, S.2
Lin, X.3
Copps, K.4
Yi, X.5
White, M.F.6
-
96
-
-
4544343980
-
Inappropriate activation of the TSC/Rheb/mTOR/S6K cassette induces IRS1/2 depletion, insulin resistance, and cell survival deficiencies
-
10.1016/j.cub.2004.08.026 15380067 1:CAS:528:DC%2BD2cXnvFansb8%3D 10.1016/j.cub.2004.08.026
-
Shah OJ, Wang Z, Hunter T (2004) Inappropriate activation of the TSC/Rheb/mTOR/S6K cassette induces IRS1/2 depletion, insulin resistance, and cell survival deficiencies. Curr Biol 14(18):1650-1656. doi: 10.1016/j.cub.2004.08.026
-
(2004)
Curr Biol
, vol.14
, Issue.18
, pp. 1650-1656
-
-
Shah, O.J.1
Wang, Z.2
Hunter, T.3
-
97
-
-
33749342069
-
Molecular mechanisms of insulin resistance: Serine phosphorylation of insulin receptor substrate-1 and increased expression of p85alpha: The two sides of a coin
-
10.2337/db06-0391 16873706 1:CAS:528:DC%2BD28Xot1Ogu7Y%3D 10.2337/db06-0391
-
Draznin B (2006) Molecular mechanisms of insulin resistance: serine phosphorylation of insulin receptor substrate-1 and increased expression of p85alpha: the two sides of a coin. Diabetes 55(8):2392-2397. doi: 10.2337/db06-0391
-
(2006)
Diabetes
, vol.55
, Issue.8
, pp. 2392-2397
-
-
Draznin, B.1
-
98
-
-
0036710280
-
IRS proteins and the common path to diabetes
-
10.1152/ajpendo.00514.2001 12169433 1:CAS:528:DC%2BD38XntFOnu7s%3D
-
White MF (2002) IRS proteins and the common path to diabetes. Am J Physiol Endocrinol Metab 283(3):E413-E422. doi: 10.1152/ajpendo.00514.2001
-
(2002)
Am J Physiol Endocrinol Metab
, vol.283
, Issue.3
-
-
White, M.F.1
-
99
-
-
84857861919
-
Mechanisms for insulin resistance: Common threads and missing links
-
10.1016/j.cell.2012.02.017 22385956 1:CAS:528:DC%2BC38XjtlSgtrg%3D 10.1016/j.cell.2012.02.017
-
Samuel VT, Shulman GI (2012) Mechanisms for insulin resistance: common threads and missing links. Cell 148(5):852-871. doi: 10.1016/j.cell.2012.02.017
-
(2012)
Cell
, vol.148
, Issue.5
, pp. 852-871
-
-
Samuel, V.T.1
Shulman, G.I.2
-
100
-
-
83655172387
-
The link between metabolic abnormalities and endothelial dysfunction in type 2 diabetes: An update
-
10.1007/s00395-011-0237-1 22189563 10.1007/s00395-011-0237-1
-
Zhang H, Dellsperger KC, Zhang C (2012) The link between metabolic abnormalities and endothelial dysfunction in type 2 diabetes: an update. Basic Res Cardiol 107(1):237. doi: 10.1007/s00395-011-0237-1
-
(2012)
Basic Res Cardiol
, vol.107
, Issue.1
, pp. 237
-
-
Zhang, H.1
Dellsperger, K.C.2
Zhang, C.3
-
101
-
-
32544432975
-
Involvement of novel PKC isoforms in FFA induced defects in insulin signaling
-
10.1016/j.mce.2005.12.014 16448741 1:CAS:528:DC%2BD28XhsF2gtLk%3D 10.1016/j.mce.2005.12.014
-
Dey D, Basu D, Roy SS, Bandyopadhyay A, Bhattacharya S (2006) Involvement of novel PKC isoforms in FFA induced defects in insulin signaling. Mol Cell Endocrinol 246(1-2):60-64. doi: 10.1016/j.mce.2005.12.014
-
(2006)
Mol Cell Endocrinol
, vol.246
, Issue.1-2
, pp. 60-64
-
-
Dey, D.1
Basu, D.2
Roy, S.S.3
Bandyopadhyay, A.4
Bhattacharya, S.5
-
102
-
-
79251548323
-
Paradoxical increase in TAG and DAG content parallel the insulin sensitizing effect of unilateral DGAT1 overexpression in rat skeletal muscle
-
10.1371/journal.pone.0014503 21264296 1:CAS:528:DC%2BC3MXhtFWnt7s%3D 10.1371/journal.pone.0014503
-
Timmers S, de Vogel-van den Bosch J, Hesselink MK, van Beurden D, Schaart G, Ferraz MJ, Losen M, Martinez-Martinez P, De Baets MH, Aerts JM, Schrauwen P (2011) Paradoxical increase in TAG and DAG content parallel the insulin sensitizing effect of unilateral DGAT1 overexpression in rat skeletal muscle. PLoS One 6(1):e14503. doi: 10.1371/journal.pone.0014503
-
(2011)
PLoS One
, vol.6
, Issue.1
, pp. 14503
-
-
Timmers, S.1
De Vogel-Van Den Bosch, J.2
Hesselink, M.K.3
Van Beurden, D.4
Schaart, G.5
Ferraz, M.J.6
Losen, M.7
Martinez-Martinez, P.8
De Baets, M.H.9
Aerts, J.M.10
Schrauwen, P.11
-
103
-
-
70349216418
-
Brain glucose transporters, O-GlcNAcylation and phosphorylation of tau in diabetes and Alzheimer's disease
-
10.1111/j.1471-4159.2009.06320.x 19659459 1:CAS:528:DC%2BD1MXht1ertLbL 10.1111/j.1471-4159.2009.06320.x
-
Liu Y, Liu F, Grundke-Iqbal I, Iqbal K, Gong CX (2009) Brain glucose transporters, O-GlcNAcylation and phosphorylation of tau in diabetes and Alzheimer's disease. J Neurochem 111(1):242-249. doi: 10.1111/j.1471-4159.2009. 06320.x
-
(2009)
J Neurochem
, vol.111
, Issue.1
, pp. 242-249
-
-
Liu, Y.1
Liu, F.2
Grundke-Iqbal, I.3
Iqbal, K.4
Gong, C.X.5
-
104
-
-
79960896430
-
Deficient brain insulin signalling pathway in Alzheimer's disease and diabetes
-
10.1002/path.2912 21598254 1:CAS:528:DC%2BC3MXpt1Cns78%3D 10.1002/path.2912
-
Liu Y, Liu F, Grundke-Iqbal I, Iqbal K, Gong CX (2011) Deficient brain insulin signalling pathway in Alzheimer's disease and diabetes. J Pathol 225(1):54-62. doi: 10.1002/path.2912
-
(2011)
J Pathol
, vol.225
, Issue.1
, pp. 54-62
-
-
Liu, Y.1
Liu, F.2
Grundke-Iqbal, I.3
Iqbal, K.4
Gong, C.X.5
-
105
-
-
57049125529
-
Defective insulin signaling pathway and increased glycogen synthase kinase-3 activity in the brain of diabetic mice: Parallels with Alzheimer's disease and correction by insulin
-
10.1002/jnr.21787 18627032 1:CAS:528:DC%2BD1cXhsVarurfF 10.1002/jnr.21787
-
Jolivalt CG, Lee CA, Beiswenger KK, Smith JL, Orlov M, Torrance MA, Masliah E (2008) Defective insulin signaling pathway and increased glycogen synthase kinase-3 activity in the brain of diabetic mice: parallels with Alzheimer's disease and correction by insulin. J Neurosci Res 86(15):3265-3274. doi: 10.1002/jnr.21787
-
(2008)
J Neurosci Res
, vol.86
, Issue.15
, pp. 3265-3274
-
-
Jolivalt, C.G.1
Lee, C.A.2
Beiswenger, K.K.3
Smith, J.L.4
Orlov, M.5
Torrance, M.A.6
Masliah, E.7
-
106
-
-
79952114000
-
The neurodevelopmental implications of PI3K signaling
-
10.1007/82-2010-82 20582530 1:CAS:528:DC%2BC3cXhsFKnsrjI 10.1007/82-2010-82
-
Waite K, Eickholt BJ (2010) The neurodevelopmental implications of PI3K signaling. Curr Top Microbiol Immunol 346:245-265. doi: 10.1007/82-2010-82
-
(2010)
Curr Top Microbiol Immunol
, vol.346
, pp. 245-265
-
-
Waite, K.1
Eickholt, B.J.2
-
107
-
-
77957729824
-
PTEN in liver diseases and cancer
-
20872961 1:CAS:528:DC%2BC3cXht1ChtbnN 10.3748/wjg.v16.i37.4627
-
Peyrou M, Bourgoin L, Foti M (2010) PTEN in liver diseases and cancer. World J Gastroenterol 16(37):4627-4633
-
(2010)
World J Gastroenterol
, vol.16
, Issue.37
, pp. 4627-4633
-
-
Peyrou, M.1
Bourgoin, L.2
Foti, M.3
-
108
-
-
33947496373
-
A small molecule inhibitor for phosphatase and tensin homologue deleted on chromosome 10 (PTEN)
-
10.1021/cb600352f 17240976 1:CAS:528:DC%2BD28Xht1yrsbjL 10.1021/cb600352f
-
Rosivatz E, Matthews JG, McDonald NQ, Mulet X, Ho KK, Lossi N, Schmid AC, Mirabelli M, Pomeranz KM, Erneux C, Lam EW, Vilar R, Woscholski R (2006) A small molecule inhibitor for phosphatase and tensin homologue deleted on chromosome 10 (PTEN). ACS Chem Biol 1(12):780-790. doi: 10.1021/cb600352f
-
(2006)
ACS Chem Biol
, vol.1
, Issue.12
, pp. 780-790
-
-
Rosivatz, E.1
Matthews, J.G.2
McDonald, N.Q.3
Mulet, X.4
Ho, K.K.5
Lossi, N.6
Schmid, A.C.7
Mirabelli, M.8
Pomeranz, K.M.9
Erneux, C.10
Lam, E.W.11
Vilar, R.12
Woscholski, R.13
-
109
-
-
1442348156
-
Human placental growth hormone increases expression of the p85 regulatory unit of phosphatidylinositol 3-kinase and triggers severe insulin resistance in skeletal muscle
-
10.1210/en.2003-1297 14633976 1:CAS:528:DC%2BD2cXhs1WisLg%3D 10.1210/en.2003-1297
-
Barbour LA, Shao J, Qiao L, Leitner W, Anderson M, Friedman JE, Draznin B (2004) Human placental growth hormone increases expression of the p85 regulatory unit of phosphatidylinositol 3-kinase and triggers severe insulin resistance in skeletal muscle. Endocrinology 145(3):1144-1150. doi: 10.1210/en.2003-1297
-
(2004)
Endocrinology
, vol.145
, Issue.3
, pp. 1144-1150
-
-
Barbour, L.A.1
Shao, J.2
Qiao, L.3
Leitner, W.4
Anderson, M.5
Friedman, J.E.6
Draznin, B.7
-
110
-
-
4544324637
-
Reversal of insulin resistance postpartum is linked to enhanced skeletal muscle insulin signaling
-
10.1210/jc.2004-0749 15356080 1:CAS:528:DC%2BD2cXnslWhu78%3D 10.1210/jc.2004-0749
-
Kirwan JP, Varastehpour A, Jing M, Presley L, Shao J, Friedman JE, Catalano PM (2004) Reversal of insulin resistance postpartum is linked to enhanced skeletal muscle insulin signaling. J Clin Endocrinol Metab 89(9):4678-4684. doi: 10.1210/jc.2004-0749
-
(2004)
J Clin Endocrinol Metab
, vol.89
, Issue.9
, pp. 4678-4684
-
-
Kirwan, J.P.1
Varastehpour, A.2
Jing, M.3
Presley, L.4
Shao, J.5
Friedman, J.E.6
Catalano, P.M.7
-
111
-
-
0036143774
-
Molecular balance between the regulatory and catalytic subunits of phosphoinositide 3-kinase regulates cell signaling and survival
-
11784871 1:CAS:528:DC%2BD38Xmt12msg%3D%3D 10.1128/MCB.22.3.965-977.2002
-
Ueki K, Fruman DA, Brachmann SM, Tseng YH, Cantley LC, Kahn CR (2002) Molecular balance between the regulatory and catalytic subunits of phosphoinositide 3-kinase regulates cell signaling and survival. Mol Cell Biol 22(3):965-977
-
(2002)
Mol Cell Biol
, vol.22
, Issue.3
, pp. 965-977
-
-
Ueki, K.1
Fruman, D.A.2
Brachmann, S.M.3
Tseng, Y.H.4
Cantley, L.C.5
Kahn, C.R.6
-
112
-
-
77953408308
-
Physiological regulation of Akt activity and stability
-
20182580 1:CAS:528:DC%2BD1MXhsFyrurvN
-
Liao Y, Hung MC (2010) Physiological regulation of Akt activity and stability. Am J Transl Res 2(1):19-42
-
(2010)
Am J Transl Res
, vol.2
, Issue.1
, pp. 19-42
-
-
Liao, Y.1
Hung, M.C.2
-
113
-
-
84863127179
-
Amplification and demultiplexing in insulin-regulated Akt protein kinase pathway in adipocytes
-
10.1074/jbc.M111.318238 22207758 1:CAS:528:DC%2BC38Xisl2ltrc%3D 10.1074/jbc.M111.318238
-
Tan SX, Ng Y, Meoli CC, Kumar A, Khoo PS, Fazakerley DJ, Junutula JR, Vali S, James DE, Stockli J (2012) Amplification and demultiplexing in insulin-regulated Akt protein kinase pathway in adipocytes. J Biol Chem 287(9):6128-6138. doi: 10.1074/jbc.M111.318238
-
(2012)
J Biol Chem
, vol.287
, Issue.9
, pp. 6128-6138
-
-
Tan, S.X.1
Ng, Y.2
Meoli, C.C.3
Kumar, A.4
Khoo, P.S.5
Fazakerley, D.J.6
Junutula, J.R.7
Vali, S.8
James, D.E.9
Stockli, J.10
-
114
-
-
2542528670
-
A family with severe insulin resistance and diabetes due to a mutation in AKT2
-
10.1126/science.1096706 15166380 1:CAS:528:DC%2BD2cXkt1Ggu7Y%3D 10.1126/science.1096706
-
George S, Rochford JJ, Wolfrum C, Gray SL, Schinner S, Wilson JC, Soos MA, Murgatroyd PR, Williams RM, Acerini CL, Dunger DB, Barford D, Umpleby AM, Wareham NJ, Davies HA, Schafer AJ, Stoffel M, O'Rahilly S, Barroso I (2004) A family with severe insulin resistance and diabetes due to a mutation in AKT2. Science 304(5675):1325-1328. doi: 10.1126/science.1096706
-
(2004)
Science
, vol.304
, Issue.5675
, pp. 1325-1328
-
-
George, S.1
Rochford, J.J.2
Wolfrum, C.3
Gray, S.L.4
Schinner, S.5
Wilson, J.C.6
Soos, M.A.7
Murgatroyd, P.R.8
Williams, R.M.9
Acerini, C.L.10
Dunger, D.B.11
Barford, D.12
Umpleby, A.M.13
Wareham, N.J.14
Davies, H.A.15
Schafer, A.J.16
Stoffel, M.17
O'Rahilly, S.18
Barroso, I.19
-
115
-
-
84859739738
-
Akt: A double-edged sword in cell proliferation and genome stability
-
10.1155/2012/951724 22481935 10.1155/2012/951724 1:CAS:528: DC%2BC38Xkslantbo%3D
-
Xu N, Lao Y, Zhang Y, Gillespie DA (2012) Akt: a double-edged sword in cell proliferation and genome stability. J Oncol 2012:951724. doi: 10.1155/2012/951724
-
(2012)
J Oncol
, vol.2012
, pp. 951724
-
-
Xu, N.1
Lao, Y.2
Zhang, Y.3
Gillespie, D.A.4
-
116
-
-
79954992390
-
Arginine methylation of BCL-2 antagonist of cell death (BAD) counteracts its phosphorylation and inactivation by Akt
-
10.1073/pnas.1015328108 21444773 1:CAS:528:DC%2BC3MXltVymtbg%3D 10.1073/pnas.1015328108
-
Sakamaki J, Daitoku H, Ueno K, Hagiwara A, Yamagata K, Fukamizu A (2011) Arginine methylation of BCL-2 antagonist of cell death (BAD) counteracts its phosphorylation and inactivation by Akt. Proc Natl Acad Sci U S A 108(15):6085-6090. doi: 10.1073/pnas.1015328108
-
(2011)
Proc Natl Acad Sci U S A
, vol.108
, Issue.15
, pp. 6085-6090
-
-
Sakamaki, J.1
Daitoku, H.2
Ueno, K.3
Hagiwara, A.4
Yamagata, K.5
Fukamizu, A.6
-
117
-
-
0141705364
-
Insulin regulates the activity of forkhead transcription factor Hnf-3beta/Foxa-2 by Akt-mediated phosphorylation and nuclear/cytosolic localization
-
10.1073/pnas.1931483100 14500912 1:CAS:528:DC%2BD3sXotFKmt7c%3D 10.1073/pnas.1931483100
-
Wolfrum C, Besser D, Luca E, Stoffel M (2003) Insulin regulates the activity of forkhead transcription factor Hnf-3beta/Foxa-2 by Akt-mediated phosphorylation and nuclear/cytosolic localization. Proc Natl Acad Sci U S A 100(20):11624-11629. doi: 10.1073/pnas.1931483100
-
(2003)
Proc Natl Acad Sci U S A
, vol.100
, Issue.20
, pp. 11624-11629
-
-
Wolfrum, C.1
Besser, D.2
Luca, E.3
Stoffel, M.4
-
118
-
-
1642464560
-
Multiple elements regulate nuclear/cytoplasmic shuttling of FOXO1: Characterization of phosphorylation- and 14-3-3-dependent and -independent mechanisms
-
10.1042/BJ20031450 14664696 1:CAS:528:DC%2BD2cXisVyktL0%3D 10.1042/BJ20031450
-
Zhao X, Gan L, Pan H, Kan D, Majeski M, Adam SA, Unterman TG (2004) Multiple elements regulate nuclear/cytoplasmic shuttling of FOXO1: characterization of phosphorylation- and 14-3-3-dependent and -independent mechanisms. Biochem J 378(Pt 3):839-849. doi: 10.1042/BJ20031450
-
(2004)
Biochem J
, vol.378
, Issue.PART 3
, pp. 839-849
-
-
Zhao, X.1
Gan, L.2
Pan, H.3
Kan, D.4
Majeski, M.5
Adam, S.A.6
Unterman, T.G.7
-
119
-
-
34250788809
-
AKT/PKB signaling: Navigating downstream
-
10.1016/j.cell.2007.06.009 17604717 1:CAS:528:DC%2BD2sXotV2hs7g%3D 10.1016/j.cell.2007.06.009
-
Manning BD, Cantley LC (2007) AKT/PKB signaling: navigating downstream. Cell 129(7):1261-1274. doi: 10.1016/j.cell.2007.06.009
-
(2007)
Cell
, vol.129
, Issue.7
, pp. 1261-1274
-
-
Manning, B.D.1
Cantley, L.C.2
-
120
-
-
13844312400
-
Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex
-
10.1126/science.1106148 15718470 1:CAS:528:DC%2BD2MXhtlSrtbY%3D 10.1126/science.1106148
-
Sarbassov DD, Guertin DA, Ali SM, Sabatini DM (2005) Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex. Science 307(5712):1098-1101. doi: 10.1126/science.1106148
-
(2005)
Science
, vol.307
, Issue.5712
, pp. 1098-1101
-
-
Sarbassov, D.D.1
Guertin, D.A.2
Ali, S.M.3
Sabatini, D.M.4
-
121
-
-
77957229010
-
Insulin signaling meets mitochondria in metabolism
-
10.1016/j.tem.2010.06.005 20638297 1:CAS:528:DC%2BC3cXht1GjtL7K 10.1016/j.tem.2010.06.005
-
Cheng Z, Tseng Y, White MF (2010) Insulin signaling meets mitochondria in metabolism. Trends Endocrinol Metab 21(10):589-598. doi: 10.1016/j.tem.2010.06. 005
-
(2010)
Trends Endocrinol Metab
, vol.21
, Issue.10
, pp. 589-598
-
-
Cheng, Z.1
Tseng, Y.2
White, M.F.3
-
122
-
-
42449104351
-
MTOR inhibition by rapamycin prevents beta-cell adaptation to hyperglycemia and exacerbates the metabolic state in type 2 diabetes
-
10.2337/db07-0922 18174523 1:CAS:528:DC%2BD1cXksVGkuro%3D 10.2337/db07-0922
-
Fraenkel M, Ketzinel-Gilad M, Ariav Y, Pappo O, Karaca M, Castel J, Berthault MF, Magnan C, Cerasi E, Kaiser N, Leibowitz G (2008) mTOR inhibition by rapamycin prevents beta-cell adaptation to hyperglycemia and exacerbates the metabolic state in type 2 diabetes. Diabetes 57(4):945-957. doi: 10.2337/db07-0922
-
(2008)
Diabetes
, vol.57
, Issue.4
, pp. 945-957
-
-
Fraenkel, M.1
Ketzinel-Gilad, M.2
Ariav, Y.3
Pappo, O.4
Karaca, M.5
Castel, J.6
Berthault, M.F.7
Magnan, C.8
Cerasi, E.9
Kaiser, N.10
Leibowitz, G.11
-
123
-
-
33846806078
-
Elevated sensitivity to diet-induced obesity and insulin resistance in mice lacking 4E-BP1 and 4E-BP2
-
10.1172/JCI29528 17273556 10.1172/JCI29528 1:CAS:528:DC%2BD2sXhs1Oqtr8%3D
-
2Le Bacquer O, Petroulakis E, Paglialunga S, Poulin F, Richard D, Cianflone K, Sonenberg N (2007) Elevated sensitivity to diet-induced obesity and insulin resistance in mice lacking 4E-BP1 and 4E-BP2. J Clin Invest 117(2):387-396. doi: 10.1172/JCI29528
-
(2007)
J Clin Invest
, vol.117
, Issue.2
, pp. 387-396
-
-
Le Bacquer, O.1
Petroulakis, E.2
Paglialunga, S.3
Poulin, F.4
Richard, D.5
Cianflone, K.6
Sonenberg, N.7
-
124
-
-
67349217986
-
Molecular mechanisms of mTOR-mediated translational control
-
10.1038/nrm2672 19339977 10.1038/nrm2672 1:CAS:528:DC%2BD1MXjvV2ltbs%3D
-
Ma XM, Blenis J (2009) Molecular mechanisms of mTOR-mediated translational control. Nat Rev Mol Cell Biol 10(5):307-318. doi: 10.1038/nrm2672
-
(2009)
Nat Rev Mol Cell Biol
, vol.10
, Issue.5
, pp. 307-318
-
-
Ma, X.M.1
Blenis, J.2
-
125
-
-
84858307317
-
Signaling mechanisms in the regulation of renal matrix metabolism in diabetes
-
10.1155/2012/749812 22454628 10.1155/2012/749812 1:CAS:528: DC%2BC38XjsVeitrw%3D
-
Mariappan MM (2012) Signaling mechanisms in the regulation of renal matrix metabolism in diabetes. Exp Diabetes Res 2012:749812. doi: 10.1155/2012/749812
-
(2012)
Exp Diabetes Res
, vol.2012
, pp. 749812
-
-
Mariappan, M.M.1
-
126
-
-
34247118887
-
Signalling to translation: How signal transduction pathways control the protein synthetic machinery
-
10.1042/BJ20070024 17376031 1:CAS:528:DC%2BD2sXjsVWrtrg%3D 10.1042/BJ20070024
-
Proud CG (2007) Signalling to translation: how signal transduction pathways control the protein synthetic machinery. Biochem J 403(2):217-234. doi: 10.1042/BJ20070024
-
(2007)
Biochem J
, vol.403
, Issue.2
, pp. 217-234
-
-
Proud, C.G.1
-
127
-
-
84856715458
-
GSK-3: Functional insights from cell biology and animal models
-
10.3389/fnmol.2011.00040 22110425 1:CAS:528:DC%2BC38XovVym 10.3389/fnmol.2011.00040
-
Kaidanovich-Beilin O, Woodgett JR (2011) GSK-3: functional Insights from Cell Biology and Animal Models. Front Mol Neurosci 4:40. doi: 10.3389/fnmol.2011.00040
-
(2011)
Front Mol Neurosci
, vol.4
, pp. 40
-
-
Kaidanovich-Beilin, O.1
Woodgett, J.R.2
-
128
-
-
84856619287
-
Modulation of GSK-3 as a therapeutic strategy on tau pathologies
-
10.3389/fnmol.2011.00024 22007157 1:CAS:528:DC%2BC38XovVOr 10.3389/fnmol.2011.00024
-
Medina M, Garrido JJ, Wandosell FG (2011) Modulation of GSK-3 as a therapeutic strategy on tau pathologies. Front Mol Neurosci 4:24. doi: 10.3389/fnmol.2011.00024
-
(2011)
Front Mol Neurosci
, vol.4
, pp. 24
-
-
Medina, M.1
Garrido, J.J.2
Wandosell, F.G.3
-
129
-
-
84855589344
-
Strategies for reducing or preventing the generation of oxidative stress
-
10.1155/2011/194586 1:STN:280:DC%2BC38%2FptlSrsQ%3D%3D
-
Poljsak B (2011) Strategies for reducing or preventing the generation of oxidative stress. Oxidative Med Cell Longev 2011:194586. doi: 10.1155/2011/194586
-
(2011)
Oxidative Med Cell Longev
, vol.2011
, pp. 194586
-
-
Poljsak, B.1
-
130
-
-
0043127453
-
Insulin receptor substrate-2 deficiency impairs brain growth and promotes tau phosphorylation
-
12904469 1:CAS:528:DC%2BD3sXmtlyhsbs%3D
-
Schubert M, Brazil DP, Burks DJ, Kushner JA, Ye J, Flint CL, Farhang-Fallah J, Dikkes P, Warot XM, Rio C, Corfas G, White MF (2003) Insulin receptor substrate-2 deficiency impairs brain growth and promotes tau phosphorylation. J Neurosci 23(18):7084-7092
-
(2003)
J Neurosci
, vol.23
, Issue.18
, pp. 7084-7092
-
-
Schubert, M.1
Brazil, D.P.2
Burks, D.J.3
Kushner, J.A.4
Ye, J.5
Flint, C.L.6
Farhang-Fallah, J.7
Dikkes, P.8
Warot, X.M.9
Rio, C.10
Corfas, G.11
White, M.F.12
-
131
-
-
66249126971
-
Metabolic links between diabetes and Alzheimer's disease
-
10.1586/ern.09.18 19402773 1:CAS:528:DC%2BD1MXlt1Cltr8%3D 10.1586/ern.09.18
-
Maher PA, Schubert DR (2009) Metabolic links between diabetes and Alzheimer's disease. Expert Rev Neurother 9(5):617-630. doi: 10.1586/ern.09.18
-
(2009)
Expert Rev Neurother
, vol.9
, Issue.5
, pp. 617-630
-
-
Maher, P.A.1
Schubert, D.R.2
-
132
-
-
84856806730
-
Elk-1 a transcription factor with multiple facets in the brain
-
10.3389/fnins.2011.00035 21441990 10.3389/fnins.2011.00035 1:CAS:528:DC%2BC38XjvFartQ%3D%3D
-
Besnard A, Galan-Rodriguez B, Vanhoutte P, Caboche J (2011) Elk-1 a transcription factor with multiple facets in the brain. Front Neurosci 5:35. doi: 10.3389/fnins.2011.00035
-
(2011)
Front Neurosci
, vol.5
, pp. 35
-
-
Besnard, A.1
Galan-Rodriguez, B.2
Vanhoutte, P.3
Caboche, J.4
-
133
-
-
84872355045
-
Fine-tuning MAPK signaling in the brain: The role of MKP-1
-
10.4161/cib.4.3.14766 21980558 10.4161/cib.4.3.14766
-
Jeanneteau F, Deinhardt K (2011) Fine-tuning MAPK signaling in the brain: the role of MKP-1. Commun Integr Biol 4(3):281-283. doi: 10.4161/cib.4.3.14766
-
(2011)
Commun Integr Biol
, vol.4
, Issue.3
, pp. 281-283
-
-
Jeanneteau, F.1
Deinhardt, K.2
-
134
-
-
4043106533
-
The roles of MAPK cascades in synaptic plasticity and memory in Aplysia: Facilitatory effects and inhibitory constraints
-
10.1101/lm.81104 15286179 10.1101/lm.81104
-
Sharma SK, Carew TJ (2004) The roles of MAPK cascades in synaptic plasticity and memory in Aplysia: facilitatory effects and inhibitory constraints. Learn Mem 11(4):373-378. doi: 10.1101/lm.81104
-
(2004)
Learn Mem
, vol.11
, Issue.4
, pp. 373-378
-
-
Sharma, S.K.1
Carew, T.J.2
-
135
-
-
1542298238
-
Importance of MAPK pathways for microglial pro-inflammatory cytokine IL-1 beta production
-
10.1016/S0197-4580(03)00126-X 15013563 1:CAS:528:DC%2BD2cXhvVyhtro%3D 10.1016/S0197-4580(03)00126-X
-
Kim SH, Smith CJ, Van Eldik LJ (2004) Importance of MAPK pathways for microglial pro-inflammatory cytokine IL-1 beta production. Neurobiol Aging 25(4):431-439. doi: 10.1016/S0197-4580(03)00126-X
-
(2004)
Neurobiol Aging
, vol.25
, Issue.4
, pp. 431-439
-
-
Kim, S.H.1
Smith, C.J.2
Van Eldik, L.J.3
-
136
-
-
84862160435
-
Activation of ERK1/2-CREB pathway during potentiating synaptic transmission of (-)clausenamide in rat dentate gyrus
-
10.1080/10286020.2011.650885 22332773 1:CAS:528:DC%2BC38XisFeisro%3D 10.1080/10286020.2011.650885
-
Hu JF, Niu F, Ning N, Duan WZ, Chu SF, Xue W, Yuan YH, Chen NH, Zhang JT (2012) Activation of ERK1/2-CREB pathway during potentiating synaptic transmission of (-)clausenamide in rat dentate gyrus. J Asian Nat Prod Res 14(3):256-262. doi: 10.1080/10286020.2011.650885
-
(2012)
J Asian Nat Prod Res
, vol.14
, Issue.3
, pp. 256-262
-
-
Hu, J.F.1
Niu, F.2
Ning, N.3
Duan, W.Z.4
Chu, S.F.5
Xue, W.6
Yuan, Y.H.7
Chen, N.H.8
Zhang, J.T.9
-
137
-
-
70350747591
-
Targeting protein kinases in central nervous system disorders
-
10.1038/nrd2999 19876042 1:CAS:528:DC%2BD1MXhtlCjtrzO 10.1038/nrd2999
-
Chico LK, Van Eldik LJ, Watterson DM (2009) Targeting protein kinases in central nervous system disorders. Nat Rev Drug Discov 8(11):892-909. doi: 10.1038/nrd2999
-
(2009)
Nat Rev Drug Discov
, vol.8
, Issue.11
, pp. 892-909
-
-
Chico, L.K.1
Van Eldik, L.J.2
Watterson, D.M.3
-
138
-
-
73449131129
-
Targeting p38 MAPK pathway for the treatment of Alzheimer's disease
-
10.1016/j.neuropharm.2009.11.010 19951717 1:CAS:528: DC%2BC3cXjtleqtg%3D%3D 10.1016/j.neuropharm.2009.11.010
-
Munoz L, Ammit AJ (2010) Targeting p38 MAPK pathway for the treatment of Alzheimer's disease. Neuropharmacology 58(3):561-568. doi: 10.1016/j.neuropharm. 2009.11.010
-
(2010)
Neuropharmacology
, vol.58
, Issue.3
, pp. 561-568
-
-
Munoz, L.1
Ammit, A.J.2
-
139
-
-
36448936747
-
Kinase activities increase during the development of tauopathy in htau mice
-
10.1111/j.1471-4159.2007.04930.x 17908241 1:CAS:528:DC%2BD2sXhsVOns7jO 10.1111/j.1471-4159.2007.04930.x
-
Kelleher I, Garwood C, Hanger DP, Anderton BH, Noble W (2007) Kinase activities increase during the development of tauopathy in htau mice. J Neurochem 103(6):2256-2267. doi: 10.1111/j.1471-4159.2007.04930.x
-
(2007)
J Neurochem
, vol.103
, Issue.6
, pp. 2256-2267
-
-
Kelleher, I.1
Garwood, C.2
Hanger, D.P.3
Anderton, B.H.4
Noble, W.5
-
140
-
-
78651274000
-
Insulin resistance and Alzheimer-like reductions in regional cerebral glucose metabolism for cognitively normal adults with prediabetes or early type 2 diabetes
-
10.1001/archneurol.2010.225 20837822 10.1001/archneurol.2010.225
-
Baker LD, Cross DJ, Minoshima S, Belongia D, Watson GS, Craft S (2011) Insulin resistance and Alzheimer-like reductions in regional cerebral glucose metabolism for cognitively normal adults with prediabetes or early type 2 diabetes. Arch Neurol 68(1):51-57. doi: 10.1001/archneurol.2010.225
-
(2011)
Arch Neurol
, vol.68
, Issue.1
, pp. 51-57
-
-
Baker, L.D.1
Cross, D.J.2
Minoshima, S.3
Belongia, D.4
Watson, G.S.5
Craft, S.6
-
141
-
-
64249129005
-
Insulin resistance and amyloidogenesis as common molecular foundation for type 2 diabetes and Alzheimer's disease
-
10.1016/j.bbadis.2008.10.014 19026743 1:CAS:528:DC%2BD1MXkvVSkt7c%3D 10.1016/j.bbadis.2008.10.014
-
Zhao WQ, Townsend M (2009) Insulin resistance and amyloidogenesis as common molecular foundation for type 2 diabetes and Alzheimer's disease. Biochim Biophys Acta 1792(5):482-496. doi: 10.1016/j.bbadis.2008.10.014
-
(2009)
Biochim Biophys Acta
, vol.1792
, Issue.5
, pp. 482-496
-
-
Zhao, W.Q.1
Townsend, M.2
-
142
-
-
4344559467
-
The glucose transporter families SGLT and GLUT: Molecular basis of normal and aberrant function
-
1:CAS:528:DC%2BD2cXnslCgt7w%3D 10.1177/0148607104028005364
-
Scheepers A, Joost HG, Schurmann A (2004) The glucose transporter families SGLT and GLUT: molecular basis of normal and aberrant function. J Parenter Enter Nutr 28(5):364-371
-
(2004)
J Parenter Enter Nutr
, vol.28
, Issue.5
, pp. 364-371
-
-
Scheepers, A.1
Joost, H.G.2
Schurmann, A.3
-
143
-
-
0033664539
-
Insulin receptors and insulin action in the brain: Review and clinical implications
-
11118610 1:CAS:528:DC%2BD3cXoslCks7k%3D 10.1016/S0149-7634(00)00040-3
-
Schulingkamp RJ, Pagano TC, Hung D, Raffa RB (2000) Insulin receptors and insulin action in the brain: review and clinical implications. Neurosci Biobehav Rev 24(8):855-872
-
(2000)
Neurosci Biobehav Rev
, vol.24
, Issue.8
, pp. 855-872
-
-
Schulingkamp, R.J.1
Pagano, T.C.2
Hung, D.3
Raffa, R.B.4
-
144
-
-
78649446153
-
Uncovering molecular biomarkers that correlate cognitive decline with the changes of hippocampus' gene expression profiles in Alzheimer's disease
-
10.1371/journal.pone.0010153 20405009 10.1371/journal.pone.0010153 1:CAS:528:DC%2BC3cXltFyit7w%3D
-
Gomez Ravetti M, Rosso OA, Berretta R, Moscato P (2010) Uncovering molecular biomarkers that correlate cognitive decline with the changes of hippocampus' gene expression profiles in Alzheimer's disease. PLoS One 5(4):e10153. doi: 10.1371/journal.pone.0010153
-
(2010)
PLoS One
, vol.5
, Issue.4
, pp. 10153
-
-
Gomez Ravetti, M.1
Rosso, O.A.2
Berretta, R.3
Moscato, P.4
-
145
-
-
35748935872
-
Amyloid beta deposition is related to decreased glucose transporter-1 levels and hippocampal atrophy in brains of aged APP/PS1 mice
-
10.1016/j.brainres.2007.08.063 17916337 1:CAS:528:DC%2BD2sXht1yls7zO 10.1016/j.brainres.2007.08.063
-
Hooijmans CR, Graven C, Dederen PJ, Tanila H, van Groen T, Kiliaan AJ (2007) Amyloid beta deposition is related to decreased glucose transporter-1 levels and hippocampal atrophy in brains of aged APP/PS1 mice. Brain Res 1181:93-103. doi: 10.1016/j.brainres.2007.08.063
-
(2007)
Brain Res
, vol.1181
, pp. 93-103
-
-
Hooijmans, C.R.1
Graven, C.2
Dederen, P.J.3
Tanila, H.4
Van Groen, T.5
Kiliaan, A.J.6
-
146
-
-
38049050725
-
Decreased glucose transporters correlate to abnormal hyperphosphorylation of tau in Alzheimer disease
-
10.1016/j.febslet.2007.12.035 18174027 1:CAS:528:DC%2BD1cXpsF2lsg%3D%3D 10.1016/j.febslet.2007.12.035
-
Liu Y, Liu F, Iqbal K, Grundke-Iqbal I, Gong CX (2008) Decreased glucose transporters correlate to abnormal hyperphosphorylation of tau in Alzheimer disease. FEBS Lett 582(2):359-364. doi: 10.1016/j.febslet.2007.12.035
-
(2008)
FEBS Lett
, vol.582
, Issue.2
, pp. 359-364
-
-
Liu, Y.1
Liu, F.2
Iqbal, K.3
Grundke-Iqbal, I.4
Gong, C.X.5
-
147
-
-
79960991183
-
The dynamic marker hypothesis of Alzheimer's disease and its implications for clinical imaging
-
21532538 1:STN:280:DC%2BC3MvnsFCnsw%3D%3D
-
Cavedo E, Frisoni GB (2011) The dynamic marker hypothesis of Alzheimer's disease and its implications for clinical imaging. Q J Nucl Med Mol Imaging 55(3):237-249
-
(2011)
Q J Nucl Med Mol Imaging
, vol.55
, Issue.3
, pp. 237-249
-
-
Cavedo, E.1
Frisoni, G.B.2
-
148
-
-
0036828751
-
Relation between medial temporal atrophy and functional brain activity during memory processing in Alzheimer's disease: A combined MRI and SPECT study
-
12397142 1:STN:280:DC%2BD38nns1WmsA%3D%3D 10.1136/jnnp.73.5.508
-
Garrido GE, Furuie SS, Buchpiguel CA, Bottino CM, Almeida OP, Cid CG, Camargo CH, Castro CC, Glabus MF, Busatto GF (2002) Relation between medial temporal atrophy and functional brain activity during memory processing in Alzheimer's disease: a combined MRI and SPECT study. J Neurol Neurosurg Psychiatry 73(5):508-516
-
(2002)
J Neurol Neurosurg Psychiatry
, vol.73
, Issue.5
, pp. 508-516
-
-
Garrido, G.E.1
Furuie, S.S.2
Buchpiguel, C.A.3
Bottino, C.M.4
Almeida, O.P.5
Cid, C.G.6
Camargo, C.H.7
Castro, C.C.8
Glabus, M.F.9
Busatto, G.F.10
-
149
-
-
12944259210
-
Cerebral metabolic and cognitive decline in persons at genetic risk for Alzheimer's disease
-
10.1073/pnas.090106797 10811879 1:CAS:528:DC%2BD3cXjvFarsbs%3D 10.1073/pnas.090106797
-
Small GW, Ercoli LM, Silverman DH, Huang SC, Komo S, Bookheimer SY, Lavretsky H, Miller K, Siddarth P, Rasgon NL, Mazziotta JC, Saxena S, Wu HM, Mega MS, Cummings JL, Saunders AM, Pericak-Vance MA, Roses AD, Barrio JR, Phelps ME (2000) Cerebral metabolic and cognitive decline in persons at genetic risk for Alzheimer's disease. Proc Natl Acad Sci U S A 97(11):6037-6042. doi: 10.1073/pnas.090106797
-
(2000)
Proc Natl Acad Sci U S A
, vol.97
, Issue.11
, pp. 6037-6042
-
-
Small, G.W.1
Ercoli, L.M.2
Silverman, D.H.3
Huang, S.C.4
Komo, S.5
Bookheimer, S.Y.6
Lavretsky, H.7
Miller, K.8
Siddarth, P.9
Rasgon, N.L.10
Mazziotta, J.C.11
Saxena, S.12
Wu, H.M.13
Mega, M.S.14
Cummings, J.L.15
Saunders, A.M.16
Pericak-Vance, M.A.17
Roses, A.D.18
Barrio, J.R.19
Phelps, M.E.20
more..
-
150
-
-
0347719366
-
Functional brain abnormalities in young adults at genetic risk for late-onset Alzheimer's dementia
-
10.1073/pnas.2635903100 14688411 1:CAS:528:DC%2BD2cXjvFamtg%3D%3D 10.1073/pnas.2635903100
-
Reiman EM, Chen K, Alexander GE, Caselli RJ, Bandy D, Osborne D, Saunders AM, Hardy J (2004) Functional brain abnormalities in young adults at genetic risk for late-onset Alzheimer's dementia. Proc Natl Acad Sci U S A 101(1):284-289. doi: 10.1073/pnas.2635903100
-
(2004)
Proc Natl Acad Sci U S A
, vol.101
, Issue.1
, pp. 284-289
-
-
Reiman, E.M.1
Chen, K.2
Alexander, G.E.3
Caselli, R.J.4
Bandy, D.5
Osborne, D.6
Saunders, A.M.7
Hardy, J.8
-
151
-
-
41649097332
-
FDG autoradiography reveals developmental and pathological effects of mutant amyloid in PDAPP transgenic mice
-
10.1016/j.ijdevneu.2008.02.003 18358666 1:CAS:528:DC%2BD1cXks1GhtLo%3D 10.1016/j.ijdevneu.2008.02.003
-
Valla J, Gonzalez-Lima F, Reiman EM (2008) FDG autoradiography reveals developmental and pathological effects of mutant amyloid in PDAPP transgenic mice. Int J Dev Neurosci 26(3-4):253-258. doi: 10.1016/j.ijdevneu.2008.02.003
-
(2008)
Int J Dev Neurosci
, vol.26
, Issue.3-4
, pp. 253-258
-
-
Valla, J.1
Gonzalez-Lima, F.2
Reiman, E.M.3
-
152
-
-
18244390483
-
Mitochondrial abnormalities in Alzheimer brain: Mechanistic implications
-
10.1002/ana.20474 15852400 1:CAS:528:DC%2BD2MXkvFykt70%3D 10.1002/ana.20474
-
Bubber P, Haroutunian V, Fisch G, Blass JP, Gibson GE (2005) Mitochondrial abnormalities in Alzheimer brain: mechanistic implications. Ann Neurol 57(5):695-703. doi: 10.1002/ana.20474
-
(2005)
Ann Neurol
, vol.57
, Issue.5
, pp. 695-703
-
-
Bubber, P.1
Haroutunian, V.2
Fisch, G.3
Blass, J.P.4
Gibson, G.E.5
-
153
-
-
0141481850
-
Inhibition of alpha-ketoglutarate dehydrogenase complex promotes cytochrome c release from mitochondria, caspase-3 activation, and necrotic cell death
-
10.1002/jnr.10756 14515360 1:CAS:528:DC%2BD3sXotVWgtL0%3D 10.1002/jnr.10756
-
Huang HM, Ou HC, Xu H, Chen HL, Fowler C, Gibson GE (2003) Inhibition of alpha-ketoglutarate dehydrogenase complex promotes cytochrome c release from mitochondria, caspase-3 activation, and necrotic cell death. J Neurosci Res 74(2):309-317. doi: 10.1002/jnr.10756
-
(2003)
J Neurosci Res
, vol.74
, Issue.2
, pp. 309-317
-
-
Huang, H.M.1
Ou, H.C.2
Xu, H.3
Chen, H.L.4
Fowler, C.5
Gibson, G.E.6
-
154
-
-
34648831384
-
Alzheimer's disease: A lesson from mitochondrial dysfunction
-
10.1089/ars.2007.1703 17678440 1:CAS:528:DC%2BD2sXhtVKqs7bK 10.1089/ars.2007.1703
-
Moreira PI, Santos MS, Oliveira CR (2007) Alzheimer's disease: a lesson from mitochondrial dysfunction. Antioxid Redox Signal 9(10):1621-1630. doi: 10.1089/ars.2007.1703
-
(2007)
Antioxid Redox Signal
, vol.9
, Issue.10
, pp. 1621-1630
-
-
Moreira, P.I.1
Santos, M.S.2
Oliveira, C.R.3
-
155
-
-
0035856980
-
Biochemistry and molecular cell biology of diabetic complications
-
10.1038/414813a 11742414 1:CAS:528:DC%2BD38Xhtlyltg%3D%3D 10.1038/414813a
-
Brownlee M (2001) Biochemistry and molecular cell biology of diabetic complications. Nature 414(6865):813-820. doi: 10.1038/414813a
-
(2001)
Nature
, vol.414
, Issue.6865
, pp. 813-820
-
-
Brownlee, M.1
-
156
-
-
84855833476
-
Role of advanced glycation end products (AGEs) in osteoporosis in diabetes
-
22023404 1:CAS:528:DC%2BC38XpvFyiug%3D%3D 10.2174/138945011798829456
-
Yamagishi S (2011) Role of advanced glycation end products (AGEs) in osteoporosis in diabetes. Curr Drug Targets 12(14):2096-2102
-
(2011)
Curr Drug Targets
, vol.12
, Issue.14
, pp. 2096-2102
-
-
Yamagishi, S.1
-
157
-
-
42049118293
-
Clinical review: The role of advanced glycation end products in progression and complications of diabetes
-
10.1210/jc.2007-1817 18182449 1:CAS:528:DC%2BD1cXks1ahtb0%3D 10.1210/jc.2007-1817
-
Goh SY, Cooper ME (2008) Clinical review: the role of advanced glycation end products in progression and complications of diabetes. J Clin Endocrinol Metab 93(4):1143-1152. doi: 10.1210/jc.2007-1817
-
(2008)
J Clin Endocrinol Metab
, vol.93
, Issue.4
, pp. 1143-1152
-
-
Goh, S.Y.1
Cooper, M.E.2
-
158
-
-
73949088883
-
RAGE-mediated signaling contributes to intraneuronal transport of amyloid-beta and neuronal dysfunction
-
10.1073/pnas.0905686106 19901339 1:CAS:528:DC%2BD1MXhsFGjtLvO
-
Takuma K, Fang F, Zhang W, Yan S, Fukuzaki E, Du H, Sosunov A, McKhann G, Funatsu Y, Nakamichi N, Nagai T, Mizoguchi H, Ibi D, Hori O, Ogawa S, Stern DM, Yamada K, Yan SS (2009) RAGE-mediated signaling contributes to intraneuronal transport of amyloid-beta and neuronal dysfunction. Proc Natl Acad Sci U S A 106(47):20021-20026. doi: 10.1073/pnas.0905686106
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, Issue.47
, pp. 20021-20026
-
-
Takuma, K.1
Fang, F.2
Zhang, W.3
Yan, S.4
Fukuzaki, E.5
Du, H.6
Sosunov, A.7
McKhann, G.8
Funatsu, Y.9
Nakamichi, N.10
Nagai, T.11
Mizoguchi, H.12
Ibi, D.13
Hori, O.14
Ogawa, S.15
Stern, D.M.16
Yamada, K.17
Yan, S.S.18
-
159
-
-
0037134269
-
Ageing and diabetes: Implications for brain function
-
12007915 1:CAS:528:DC%2BD38XjsVSktbY%3D 10.1016/S0014-2999(02)01486-3
-
Biessels GJ, van der Heide LP, Kamal A, Bleys RL, Gispen WH (2002) Ageing and diabetes: implications for brain function. Eur J Pharmacol 441(1-2):1-14
-
(2002)
Eur J Pharmacol
, vol.441
, Issue.1-2
, pp. 1-14
-
-
Biessels, G.J.1
Van Der Heide, L.P.2
Kamal, A.3
Bleys, R.L.4
Gispen, W.H.5
-
160
-
-
67649739088
-
RAGE and Alzheimer's disease: A progression factor for amyloid-beta-induced cellular perturbation?
-
10.3233/JAD-2009-1030 19387116
-
Yan SD, Bierhaus A, Nawroth PP, Stern DM (2009) RAGE and Alzheimer's disease: a progression factor for amyloid-beta-induced cellular perturbation? J Alzheimers Dis 16(4):833-843. doi: 10.3233/JAD-2009-1030
-
(2009)
J Alzheimers Dis
, vol.16
, Issue.4
, pp. 833-843
-
-
Yan, S.D.1
Bierhaus, A.2
Nawroth, P.P.3
Stern, D.M.4
-
161
-
-
0013615899
-
RAGE and amyloid-beta peptide neurotoxicity in Alzheimer's disease
-
10.1038/382685a0 8751438 1:CAS:528:DyaK28Xlt1yltr0%3D 10.1038/382685a0
-
Yan SD, Chen X, Fu J, Chen M, Zhu H, Roher A, Slattery T, Zhao L, Nagashima M, Morser J, Migheli A, Nawroth P, Stern D, Schmidt AM (1996) RAGE and amyloid-beta peptide neurotoxicity in Alzheimer's disease. Nature 382(6593):685-691. doi: 10.1038/382685a0
-
(1996)
Nature
, vol.382
, Issue.6593
, pp. 685-691
-
-
Yan, S.D.1
Chen, X.2
Fu, J.3
Chen, M.4
Zhu, H.5
Roher, A.6
Slattery, T.7
Zhao, L.8
Nagashima, M.9
Morser, J.10
Migheli, A.11
Nawroth, P.12
Stern, D.13
Schmidt, A.M.14
-
162
-
-
0037703255
-
RAGE mediates amyloid-beta peptide transport across the blood-brain barrier and accumulation in brain
-
10.1038/nm890 12808450 1:CAS:528:DC%2BD3sXkvFOjsL0%3D 10.1038/nm890
-
Deane R, Du Yan S, Submamaryan RK, LaRue B, Jovanovic S, Hogg E, Welch D, Manness L, Lin C, Yu J, Zhu H, Ghiso J, Frangione B, Stern A, Schmidt AM, Armstrong DL, Arnold B, Liliensiek B, Nawroth P, Hofman F, Kindy M, Stern D, Zlokovic B (2003) RAGE mediates amyloid-beta peptide transport across the blood-brain barrier and accumulation in brain. Nat Med 9(7):907-913. doi: 10.1038/nm890
-
(2003)
Nat Med
, vol.9
, Issue.7
, pp. 907-913
-
-
Deane, R.1
Du Yan, S.2
Submamaryan, R.K.3
Larue, B.4
Jovanovic, S.5
Hogg, E.6
Welch, D.7
Manness, L.8
Lin, C.9
Yu, J.10
Zhu, H.11
Ghiso, J.12
Frangione, B.13
Stern, A.14
Schmidt, A.M.15
Armstrong, D.L.16
Arnold, B.17
Liliensiek, B.18
Nawroth, P.19
Hofman, F.20
Kindy, M.21
Stern, D.22
Zlokovic, B.23
more..
-
163
-
-
79951754336
-
Role of insulin signaling in the interaction between Alzheimer disease and diabetes mellitus: A missing link to therapeutic potential
-
1:CAS:528:DC%2BC3MXptVOgtbs%3D 10.2174/1874609811104020118
-
Sato N, Takeda S, Uchio-Yamada K, Ueda H, Fujisawa T, Rakugi H, Morishita R (2011) Role of insulin signaling in the interaction between Alzheimer disease and diabetes mellitus: a missing link to therapeutic potential. Cur Aging Sci 4(2):118-127
-
(2011)
Cur Aging Sci
, vol.4
, Issue.2
, pp. 118-127
-
-
Sato, N.1
Takeda, S.2
Uchio-Yamada, K.3
Ueda, H.4
Fujisawa, T.5
Rakugi, H.6
Morishita, R.7
-
164
-
-
84859723641
-
A multimodal RAGE-specific inhibitor reduces amyloid beta-mediated brain disorder in a mouse model of Alzheimer disease
-
10.1172/JCI58642 22406537 1:CAS:528:DC%2BC38Xlt1egurw%3D 10.1172/JCI58642
-
Deane R, Singh I, Sagare AP, Bell RD, Ross NT, LaRue B, Love R, Perry S, Paquette N, Deane RJ, Thiyagarajan M, Zarcone T, Fritz G, Friedman AE, Miller BL, Zlokovic BV (2012) A multimodal RAGE-specific inhibitor reduces amyloid beta-mediated brain disorder in a mouse model of Alzheimer disease. J Clin Investig 122(4):1377-1392. doi: 10.1172/JCI58642
-
(2012)
J Clin Investig
, vol.122
, Issue.4
, pp. 1377-1392
-
-
Deane, R.1
Singh, I.2
Sagare, A.P.3
Bell, R.D.4
Ross, N.T.5
Larue, B.6
Love, R.7
Perry, S.8
Paquette, N.9
Deane, R.J.10
Thiyagarajan, M.11
Zarcone, T.12
Fritz, G.13
Friedman, A.E.14
Miller, B.L.15
Zlokovic, B.V.16
-
165
-
-
80053405714
-
Receptor for advanced glycation end products (RAGE) prevents endothelial cell membrane resealing and regulates F-actin remodeling in a beta-catenin-dependent manner
-
10.1074/jbc.M111.261073 21844192 1:CAS:528:DC%2BC3MXht1CqtLbE 10.1074/jbc.M111.261073
-
Xiong F, Leonov S, Howard AC, Xiong S, Zhang B, Mei L, McNeil P, Simon S, Xiong WC (2011) Receptor for advanced glycation end products (RAGE) prevents endothelial cell membrane resealing and regulates F-actin remodeling in a beta-catenin-dependent manner. J Biol Chem 286(40):35061-35070. doi: 10.1074/jbc.M111.261073
-
(2011)
J Biol Chem
, vol.286
, Issue.40
, pp. 35061-35070
-
-
Xiong, F.1
Leonov, S.2
Howard, A.C.3
Xiong, S.4
Zhang, B.5
Mei, L.6
McNeil, P.7
Simon, S.8
Xiong, W.C.9
-
166
-
-
3242739968
-
O-GlcNAcylation regulates phosphorylation of tau: A mechanism involved in Alzheimer's disease
-
10.1073/pnas.0400348101 15249677 1:CAS:528:DC%2BD2cXmtFWmtLs%3D 10.1073/pnas.0400348101
-
Liu F, Iqbal K, Grundke-Iqbal I, Hart GW, Gong CX (2004) O-GlcNAcylation regulates phosphorylation of tau: a mechanism involved in Alzheimer's disease. Proc Natl Acad Sci U S A 101(29):10804-10809. doi: 10.1073/pnas.0400348101
-
(2004)
Proc Natl Acad Sci U S A
, vol.101
, Issue.29
, pp. 10804-10809
-
-
Liu, F.1
Iqbal, K.2
Grundke-Iqbal, I.3
Hart, G.W.4
Gong, C.X.5
-
167
-
-
16644369554
-
The potential role of tau protein O-glycosylation in Alzheimer's disease
-
15505370 1:CAS:528:DC%2BD2cXoslemtrY%3D
-
Robertson LA, Moya KL, Breen KC (2004) The potential role of tau protein O-glycosylation in Alzheimer's disease. J Alzheimers Dis 6(5):489-495
-
(2004)
J Alzheimers Dis
, vol.6
, Issue.5
, pp. 489-495
-
-
Robertson, L.A.1
Moya, K.L.2
Breen, K.C.3
-
168
-
-
9444252281
-
Insulin stimulates and diabetes inhibits O-linked N-acetylglucosamine transferase and O-glycosylation of Sp1
-
15561949 1:CAS:528:DC%2BD2cXhtVOls7nK 10.2337/diabetes.53.12.3184
-
Majumdar G, Wright J, Markowitz P, Martinez-Hernandez A, Raghow R, Solomon SS (2004) Insulin stimulates and diabetes inhibits O-linked N-acetylglucosamine transferase and O-glycosylation of Sp1. Diabetes 53(12):3184-3192
-
(2004)
Diabetes
, vol.53
, Issue.12
, pp. 3184-3192
-
-
Majumdar, G.1
Wright, J.2
Markowitz, P.3
Martinez-Hernandez, A.4
Raghow, R.5
Solomon, S.S.6
-
169
-
-
67650072530
-
Reduced O-GlcNAcylation links lower brain glucose metabolism and tau pathology in Alzheimer's disease
-
10.1093/brain/awp099 19451179 10.1093/brain/awp099
-
Liu F, Shi J, Tanimukai H, Gu J, Gu J, Grundke-Iqbal I, Iqbal K, Gong CX (2009) Reduced O-GlcNAcylation links lower brain glucose metabolism and tau pathology in Alzheimer's disease. Brain 132(Pt 7):1820-1832. doi: 10.1093/brain/awp099
-
(2009)
Brain
, vol.132
, Issue.PART 7
, pp. 1820-1832
-
-
Liu, F.1
Shi, J.2
Tanimukai, H.3
Gu, J.4
Gu, J.5
Grundke-Iqbal, I.6
Iqbal, K.7
Gong, C.X.8
-
170
-
-
84858664547
-
Increasing O-GlcNAc slows neurodegeneration and stabilizes tau against aggregation
-
10.1038/nchembio.797 22366723 1:CAS:528:DC%2BC38Xislygu7c%3D 10.1038/nchembio.797
-
Yuzwa SA, Shan X, Macauley MS, Clark T, Skorobogatko Y, Vosseller K, Vocadlo DJ (2012) Increasing O-GlcNAc slows neurodegeneration and stabilizes tau against aggregation. Nat Chem Biol 8(4):393-399. doi: 10.1038/nchembio.797
-
(2012)
Nat Chem Biol
, vol.8
, Issue.4
, pp. 393-399
-
-
Yuzwa, S.A.1
Shan, X.2
MacAuley, M.S.3
Clark, T.4
Skorobogatko, Y.5
Vosseller, K.6
Vocadlo, D.J.7
-
171
-
-
79251623365
-
Diabetes mellitus and Alzheimer's disease: Shared pathology and treatment?
-
10.1111/j.1365-2125.2010.03830.x 21284695 1:CAS:528:DC%2BC3MXjvFSnurk%3D 10.1111/j.1365-2125.2010.03830.x
-
Akter K, Lanza EA, Martin SA, Myronyuk N, Rua M, Raffa RB (2011) Diabetes mellitus and Alzheimer's disease: shared pathology and treatment? Br J Clin Pharmacol 71(3):365-376. doi: 10.1111/j.1365-2125.2010.03830.x
-
(2011)
Br J Clin Pharmacol
, vol.71
, Issue.3
, pp. 365-376
-
-
Akter, K.1
Lanza, E.A.2
Martin, S.A.3
Myronyuk, N.4
Rua, M.5
Raffa, R.B.6
-
172
-
-
84255163024
-
Receptor for AGE (RAGE): Signaling mechanisms in the pathogenesis of diabetes and its complications
-
10.1111/j.1749-6632.2011.06320.x 22211895 1:CAS:528:DC%2BC38XivVynsLY%3D 10.1111/j.1749-6632.2011.06320.x
-
Ramasamy R, Yan SF, Schmidt AM (2011) Receptor for AGE (RAGE): signaling mechanisms in the pathogenesis of diabetes and its complications. Ann N Y Acad Sci 1243:88-102. doi: 10.1111/j.1749-6632.2011.06320.x
-
(2011)
Ann N y Acad Sci
, vol.1243
, pp. 88-102
-
-
Ramasamy, R.1
Yan, S.F.2
Schmidt, A.M.3
-
173
-
-
79954585505
-
Advanced glycation endproducts and their receptor RAGE in Alzheimer's disease
-
10.1016/j.neurobiolaging.2009.04.016 19464758 1:CAS:528: DC%2BC3MXkvVWmsrw%3D 10.1016/j.neurobiolaging.2009.04.016
-
Srikanth V, Maczurek A, Phan T, Steele M, Westcott B, Juskiw D, Munch G (2011) Advanced glycation endproducts and their receptor RAGE in Alzheimer's disease. Neurobiol Aging 32(5):763-777. doi: 10.1016/j.neurobiolaging.2009.04. 016
-
(2011)
Neurobiol Aging
, vol.32
, Issue.5
, pp. 763-777
-
-
Srikanth, V.1
MacZurek, A.2
Phan, T.3
Steele, M.4
Westcott, B.5
Juskiw, D.6
Munch, G.7
-
174
-
-
74049099554
-
The relationship between Alzheimer's disease and diabetes: Type 3 diabetes?
-
20030463
-
Kroner Z (2009) The relationship between Alzheimer's disease and diabetes: type 3 diabetes? Altern Med Rev 14(4):373-379
-
(2009)
Altern Med Rev
, vol.14
, Issue.4
, pp. 373-379
-
-
Kroner, Z.1
-
175
-
-
79955051063
-
Linking lipids to Alzheimer's disease: Cholesterol and beyond
-
10.1038/nrn3012 21448224 10.1038/nrn3012 1:CAS:528:DC%2BC3MXjvFOnt70%3D
-
Di Paolo G, Kim TW (2011) Linking lipids to Alzheimer's disease: cholesterol and beyond. Nat Rev Neurosci 12(5):284-296. doi: 10.1038/nrn3012
-
(2011)
Nat Rev Neurosci
, vol.12
, Issue.5
, pp. 284-296
-
-
Di Paolo, G.1
Kim, T.W.2
-
176
-
-
0036581966
-
Diabetic dyslipidemia
-
12044586 1:CAS:528:DC%2BD38XktVKltLk%3D 10.1016/S1567-5688(01)00006-X
-
Taskinen MR (2002) Diabetic dyslipidemia. Atheroscler Suppl 3(1):47-51
-
(2002)
Atheroscler Suppl
, vol.3
, Issue.1
, pp. 47-51
-
-
Taskinen, M.R.1
-
177
-
-
3242677874
-
Modulation of the arachidonic cascade with omega3 fatty acids or analogues: Potential therapeutic benefits
-
15279600 1:CAS:528:DC%2BD2cXlslWktLg%3D 10.2174/1389557043403738
-
Roland I, De Leval X, Evrard B, Pirotte B, Dogne JM, Delattre L (2004) Modulation of the arachidonic cascade with omega3 fatty acids or analogues: potential therapeutic benefits. Mini Rev Med Chem 4(6):659-668
-
(2004)
Mini Rev Med Chem
, vol.4
, Issue.6
, pp. 659-668
-
-
Roland, I.1
De Leval, X.2
Evrard, B.3
Pirotte, B.4
Dogne, J.M.5
Delattre, L.6
-
178
-
-
17144380822
-
The metabolic syndrome
-
10.1016/S0140-6736(05)66378-7 15836891 1:CAS:528:DC%2BD2MXjsVegtbg%3D 10.1016/S0140-6736(05)66378-7
-
Eckel RH, Grundy SM, Zimmet PZ (2005) The metabolic syndrome. Lancet 365(9468):1415-1428. doi: 10.1016/S0140-6736(05)66378-7
-
(2005)
Lancet
, vol.365
, Issue.9468
, pp. 1415-1428
-
-
Eckel, R.H.1
Grundy, S.M.2
Zimmet, P.Z.3
-
179
-
-
79953769393
-
Lipid metabolism and glial lipoproteins in the central nervous system
-
21467629 1:CAS:528:DC%2BC38XpslaksA%3D%3D 10.1248/bpb.34.453
-
Hayashi H (2011) Lipid metabolism and glial lipoproteins in the central nervous system. Biol Pharm Bull 34(4):453-461
-
(2011)
Biol Pharm Bull
, vol.34
, Issue.4
, pp. 453-461
-
-
Hayashi, H.1
-
180
-
-
4644371176
-
Lipoproteins, glycoxidation and diabetic angiopathy
-
10.1002/dmrr.491 1:CAS:528:DC%2BD2cXptV2nuro%3D 10.1002/dmrr.491
-
Jenkins AJ, Best JD, Klein RL, Lyons TJ (2004) Lipoproteins, glycoxidation and diabetic angiopathy. Diabetes Metabol Res Rev 20(5):349-368. doi: 10.1002/dmrr.491
-
(2004)
Diabetes Metabol Res Rev
, vol.20
, Issue.5
, pp. 349-368
-
-
Jenkins, A.J.1
Best, J.D.2
Klein, R.L.3
Lyons, T.J.4
-
181
-
-
33745756094
-
Cholesterol metabolism in the brain: Importance of 24S-hydroxylation
-
10.1111/j.1600-0404.2006.00683.x 16866909 1:STN:280: DC%2BD28vktlejtw%3D%3D 10.1111/j.1600-0404.2006.00683.x
-
Lutjohann D (2006) Cholesterol metabolism in the brain: importance of 24S-hydroxylation. Acta Neurol Scand Suppl 185:33-42. doi: 10.1111/j.1600-0404. 2006.00683.x
-
(2006)
Acta Neurol Scand Suppl
, vol.185
, pp. 33-42
-
-
Lutjohann, D.1
-
182
-
-
0037900150
-
In vitro inhibition of insulin-degrading enzyme by long-chain fatty acids and their coenzyme A thioesters
-
12746301 1:CAS:528:DC%2BD3sXktFehurk%3D 10.1210/en.2002-0007
-
Hamel FG, Upward JL, Bennett RG (2003) In vitro inhibition of insulin-degrading enzyme by long-chain fatty acids and their coenzyme A thioesters. Endocrinology 144(6):2404-2408
-
(2003)
Endocrinology
, vol.144
, Issue.6
, pp. 2404-2408
-
-
Hamel, F.G.1
Upward, J.L.2
Bennett, R.G.3
-
183
-
-
0023788829
-
Role of arachidonic acid and other free fatty acids in mitochondrial dysfunction in brain ischemia
-
10.1002/jnr.490200407 3141627 1:CAS:528:DyaL1cXmt1Orur4%3D 10.1002/jnr.490200407
-
Hillered L, Chan PH (1988) Role of arachidonic acid and other free fatty acids in mitochondrial dysfunction in brain ischemia. J Neurosci Res 20(4):451-456. doi: 10.1002/jnr.490200407
-
(1988)
J Neurosci Res
, vol.20
, Issue.4
, pp. 451-456
-
-
Hillered, L.1
Chan, P.H.2
-
184
-
-
42049114647
-
5-Lipoxygenase gene disruption reduces amyloid-beta pathology in a mouse model of Alzheimer's disease
-
10.1096/fj.07-9131.com 17998412 1:CAS:528:DC%2BD1cXktlWntr0%3D 10.1096/fj.07-9131.com
-
Firuzi O, Zhuo J, Chinnici CM, Wisniewski T, Pratico D (2008) 5-Lipoxygenase gene disruption reduces amyloid-beta pathology in a mouse model of Alzheimer's disease. FASEB J 22(4):1169-1178. doi: 10.1096/fj.07-9131.com
-
(2008)
FASEB J
, vol.22
, Issue.4
, pp. 1169-1178
-
-
Firuzi, O.1
Zhuo, J.2
Chinnici, C.M.3
Wisniewski, T.4
Pratico, D.5
-
185
-
-
54949130109
-
Phospholipase A2 reduction ameliorates cognitive deficits in a mouse model of Alzheimer's disease
-
10.1038/nn.2213 18931664 1:CAS:528:DC%2BD1cXht12ltrrP 10.1038/nn.2213
-
Sanchez-Mejia RO, Newman JW, Toh S, Yu GQ, Zhou Y, Halabisky B, Cisse M, Scearce-Levie K, Cheng IH, Gan L, Palop JJ, Bonventre JV, Mucke L (2008) Phospholipase A2 reduction ameliorates cognitive deficits in a mouse model of Alzheimer's disease. Nat Neurosci 11(11):1311-1318. doi: 10.1038/nn.2213
-
(2008)
Nat Neurosci
, vol.11
, Issue.11
, pp. 1311-1318
-
-
Sanchez-Mejia, R.O.1
Newman, J.W.2
Toh, S.3
Yu, G.Q.4
Zhou, Y.5
Halabisky, B.6
Cisse, M.7
Scearce-Levie, K.8
Cheng, I.H.9
Gan, L.10
Palop, J.J.11
Bonventre, J.V.12
Mucke, L.13
-
186
-
-
0035884148
-
Activation of NADPH oxidase-related proton and electron currents in human eosinophils by arachidonic acid
-
11559775 1:CAS:528:DC%2BD3MXnsVeku74%3D 10.1111/j.1469-7793.2001.00783.x
-
Cherny VV, Henderson LM, Xu W, Thomas LL, DeCoursey TE (2001) Activation of NADPH oxidase-related proton and electron currents in human eosinophils by arachidonic acid. J Physiol 535(Pt 3):783-794
-
(2001)
J Physiol
, vol.535
, Issue.PART 3
, pp. 783-794
-
-
Cherny, V.V.1
Henderson, L.M.2
Xu, W.3
Thomas, L.L.4
Decoursey, T.E.5
-
187
-
-
33751079341
-
Phospholipases A2 mediate amyloid-beta peptide-induced mitochondrial dysfunction
-
10.1523/JNEUROSCI.3505-06.2006 1:CAS:528:DC%2BD28XhtFymsLnJ 10.1523/JNEUROSCI.3505-06.2006
-
Zhu D, Lai Y, Shelat PB, Hu C, Sun GY, Lee JC (2006) Phospholipases A2 mediate amyloid-beta peptide-induced mitochondrial dysfunction. J Neurosci Off J Soc Neurosci 26(43):11111-11119. doi: 10.1523/JNEUROSCI.3505-06.2006
-
(2006)
J Neurosci off J Soc Neurosci
, vol.26
, Issue.43
, pp. 11111-11119
-
-
Zhu, D.1
Lai, Y.2
Shelat, P.B.3
Hu, C.4
Sun, G.Y.5
Lee, J.C.6
-
188
-
-
2942530420
-
Arachidonic acid released by phospholipase A(2) activation triggers Ca(2+)-dependent apoptosis through the mitochondrial pathway
-
10.1074/jbc.M310381200 15070903 1:CAS:528:DC%2BD2cXksFyhu7c%3D 10.1074/jbc.M310381200
-
Penzo D, Petronilli V, Angelin A, Cusan C, Colonna R, Scorrano L, Pagano F, Prato M, Di Lisa F, Bernardi P (2004) Arachidonic acid released by phospholipase A(2) activation triggers Ca(2+)-dependent apoptosis through the mitochondrial pathway. J Biol Chem 279(24):25219-25225. doi: 10.1074/jbc.M310381200
-
(2004)
J Biol Chem
, vol.279
, Issue.24
, pp. 25219-25225
-
-
Penzo, D.1
Petronilli, V.2
Angelin, A.3
Cusan, C.4
Colonna, R.5
Scorrano, L.6
Pagano, F.7
Prato, M.8
Di Lisa, F.9
Bernardi, P.10
-
189
-
-
0032526940
-
The regulation of reactive oxygen species production during programmed cell death
-
9628898 1:CAS:528:DyaK1cXjvFKktr8%3D 10.1083/jcb.141.6.1423
-
Tan S, Sagara Y, Liu Y, Maher P, Schubert D (1998) The regulation of reactive oxygen species production during programmed cell death. J Cell Biol 141(6):1423-1432
-
(1998)
J Cell Biol
, vol.141
, Issue.6
, pp. 1423-1432
-
-
Tan, S.1
Sagara, Y.2
Liu, Y.3
Maher, P.4
Schubert, D.5
-
190
-
-
79251535878
-
Involvement of 5-lipoxygenase in the corticosteroid-dependent amyloid beta formation: In vitro and in vivo evidence
-
10.1371/journal.pone.0015163 21253592 1:CAS:528:DC%2BC3MXosVyhtA%3D%3D 10.1371/journal.pone.0015163
-
Puccio S, Chu J, Pratico D (2011) Involvement of 5-lipoxygenase in the corticosteroid-dependent amyloid beta formation: in vitro and in vivo evidence. PLoS One 6(1):e15163. doi: 10.1371/journal.pone.0015163
-
(2011)
PLoS One
, vol.6
, Issue.1
, pp. 15163
-
-
Puccio, S.1
Chu, J.2
Pratico, D.3
-
191
-
-
0141538107
-
Cyclooxygenase-2 biology
-
14529398 1:CAS:528:DC%2BD3sXnsV2msrs%3D 10.2174/1381612033454054
-
Claria J (2003) Cyclooxygenase-2 biology. Curr Pharm Des 9(27):2177-2190
-
(2003)
Curr Pharm des
, vol.9
, Issue.27
, pp. 2177-2190
-
-
Claria, J.1
-
192
-
-
34548121631
-
The roles of NADPH oxidase and phospholipases A2 in oxidative and inflammatory responses in neurodegenerative diseases
-
10.1111/j.1471-4159.2007.04670.x 17561938 1:CAS:528:DC%2BD2sXhtF2qu7jF 10.1111/j.1471-4159.2007.05003.x
-
Sun GY, Horrocks LA, Farooqui AA (2007) The roles of NADPH oxidase and phospholipases A2 in oxidative and inflammatory responses in neurodegenerative diseases. J Neurochem 103(1):1-16. doi: 10.1111/j.1471-4159.2007.04670.x
-
(2007)
J Neurochem
, vol.103
, Issue.1
, pp. 1-16
-
-
Sun, G.Y.1
Horrocks, L.A.2
Farooqui, A.A.3
-
193
-
-
77957898888
-
How does diabetes accelerate Alzheimer disease pathology?
-
10.1038/nrneurol.2010.130 20842183 1:CAS:528:DC%2BC3cXht1Gku7bP 10.1038/nrneurol.2010.130
-
Sims-Robinson C, Kim B, Rosko A, Feldman EL (2010) How does diabetes accelerate Alzheimer disease pathology? Nat Rev Neurol 6(10):551-559. doi: 10.1038/nrneurol.2010.130
-
(2010)
Nat Rev Neurol
, vol.6
, Issue.10
, pp. 551-559
-
-
Sims-Robinson, C.1
Kim, B.2
Rosko, A.3
Feldman, E.L.4
-
194
-
-
34147119059
-
Metabolic syndrome and cognitive decline
-
17430234 1:CAS:528:DC%2BD2sXksVWktrY%3D 10.2174/156720507780362191
-
Yaffe K (2007) Metabolic syndrome and cognitive decline. Curr Alzheimer Res 4(2):123-126
-
(2007)
Curr Alzheimer Res
, vol.4
, Issue.2
, pp. 123-126
-
-
Yaffe, K.1
-
195
-
-
0035083555
-
Cholesterol metabolism in the brain
-
11264981 1:CAS:528:DC%2BD3MXislWgsbo%3D 10.1097/00041433-200104000-00003
-
Dietschy JM, Turley SD (2001) Cholesterol metabolism in the brain. Curr Opin Lipidol 12(2):105-112
-
(2001)
Curr Opin Lipidol
, vol.12
, Issue.2
, pp. 105-112
-
-
Dietschy, J.M.1
Turley, S.D.2
-
196
-
-
33751096969
-
Crossing the barrier: Oxysterols as cholesterol transporters and metabolic modulators in the brain
-
10.1111/j.1365-2796.2006.01725.x 17116000 1:CAS:528: DC%2BD2sXktlWguw%3D%3D 10.1111/j.1365-2796.2006.01725.x
-
Bjorkhem I (2006) Crossing the barrier: oxysterols as cholesterol transporters and metabolic modulators in the brain. J Intern Med 260(6):493-508. doi: 10.1111/j.1365-2796.2006.01725.x
-
(2006)
J Intern Med
, vol.260
, Issue.6
, pp. 493-508
-
-
Bjorkhem, I.1
-
197
-
-
33749073795
-
Cholesterol sensing, trafficking, and esterification
-
10.1146/annurev.cellbio.22.010305.104656 16753029 1:CAS:528: DC%2BD28Xht1yjs7vP 10.1146/annurev.cellbio.22.010305.104656
-
Chang TY, Chang CC, Ohgami N, Yamauchi Y (2006) Cholesterol sensing, trafficking, and esterification. Annu Rev Cell Dev Biol 22:129-157. doi: 10.1146/annurev.cellbio.22.010305.104656
-
(2006)
Annu Rev Cell Dev Biol
, vol.22
, pp. 129-157
-
-
Chang, T.Y.1
Chang, C.C.2
Ohgami, N.3
Yamauchi, Y.4
-
198
-
-
23744498856
-
Crossing the barrier: Net flux of 27-hydroxycholesterol into the human brain
-
10.1194/jlr.M500024-JLR200 15741649 1:CAS:528:DC%2BD2MXktFaqurY%3D 10.1194/jlr.M500024-JLR200
-
Heverin M, Meaney S, Lutjohann D, Diczfalusy U, Wahren J, Bjorkhem I (2005) Crossing the barrier: net flux of 27-hydroxycholesterol into the human brain. J Lipid Res 46(5):1047-1052. doi: 10.1194/jlr.M500024-JLR200
-
(2005)
J Lipid Res
, vol.46
, Issue.5
, pp. 1047-1052
-
-
Heverin, M.1
Meaney, S.2
Lutjohann, D.3
Diczfalusy, U.4
Wahren, J.5
Bjorkhem, I.6
-
199
-
-
0034017316
-
Lipoproteins in the central nervous system
-
10818504 1:CAS:528:DC%2BD3cXjsFChtbs%3D 10.1111/j.1749-6632.2000.tb06365. x
-
Ladu MJ, Reardon C, Van Eldik L, Fagan AM, Bu G, Holtzman D, Getz GS (2000) Lipoproteins in the central nervous system. Ann N Y Acad Sci 903:167-175
-
(2000)
Ann N y Acad Sci
, vol.903
, pp. 167-175
-
-
Ladu, M.J.1
Reardon, C.2
Van Eldik, L.3
Fagan, A.M.4
Bu, G.5
Holtzman, D.6
Getz, G.S.7
-
200
-
-
77953273408
-
ACAT inhibition and amyloid beta reduction
-
10.1016/j.bbalip.2010.04.003 20398792 1:CAS:528:DC%2BC3cXntlagsLs%3D 10.1016/j.bbalip.2010.04.003
-
Bhattacharyya R, Kovacs DM (2010) ACAT inhibition and amyloid beta reduction. Biochim Biophys Acta 1801(8):960-965. doi: 10.1016/j.bbalip.2010.04. 003
-
(2010)
Biochim Biophys Acta
, vol.1801
, Issue.8
, pp. 960-965
-
-
Bhattacharyya, R.1
Kovacs, D.M.2
-
201
-
-
5144227934
-
The ACAT inhibitor CP-113,818 markedly reduces amyloid pathology in a mouse model of Alzheimer's disease
-
10.1016/j.neuron.2004.08.043 15473963 1:CAS:528:DC%2BD2cXpslOgsLk%3D 10.1016/j.neuron.2004.08.043
-
Hutter-Paier B, Huttunen HJ, Puglielli L, Eckman CB, Kim DY, Hofmeister A, Moir RD, Domnitz SB, Frosch MP, Windisch M, Kovacs DM (2004) The ACAT inhibitor CP-113,818 markedly reduces amyloid pathology in a mouse model of Alzheimer's disease. Neuron 44(2):227-238. doi: 10.1016/j.neuron.2004.08.043
-
(2004)
Neuron
, vol.44
, Issue.2
, pp. 227-238
-
-
Hutter-Paier, B.1
Huttunen, H.J.2
Puglielli, L.3
Eckman, C.B.4
Kim, D.Y.5
Hofmeister, A.6
Moir, R.D.7
Domnitz, S.B.8
Frosch, M.P.9
Windisch, M.10
Kovacs, D.M.11
-
202
-
-
0032568552
-
Cholesterol depletion inhibits the generation of beta-amyloid in hippocampal neurons
-
9600988 1:CAS:528:DyaK1cXjtlKgt7o%3D 10.1073/pnas.95.11.6460
-
Simons M, Keller P, De Strooper B, Beyreuther K, Dotti CG, Simons K (1998) Cholesterol depletion inhibits the generation of beta-amyloid in hippocampal neurons. Proc Natl Acad Sci U S A 95(11):6460-6464
-
(1998)
Proc Natl Acad Sci U S A
, vol.95
, Issue.11
, pp. 6460-6464
-
-
Simons, M.1
Keller, P.2
De Strooper, B.3
Beyreuther, K.4
Dotti, C.G.5
Simons, K.6
-
203
-
-
77953280950
-
Membrane rafts in Alzheimer's disease beta-amyloid production
-
10.1016/j.bbalip.2010.03.007 20303415 1:CAS:528:DC%2BC3cXntlags70%3D 10.1016/j.bbalip.2010.03.007
-
Vetrivel KS, Thinakaran G (2010) Membrane rafts in Alzheimer's disease beta-amyloid production. Biochim Biophys Acta 1801(8):860-867. doi: 10.1016/j.bbalip.2010.03.007
-
(2010)
Biochim Biophys Acta
, vol.1801
, Issue.8
, pp. 860-867
-
-
Vetrivel, K.S.1
Thinakaran, G.2
-
204
-
-
44649197748
-
ApoE promotes the proteolytic degradation of Abeta
-
10.1016/j.neuron.2008.04.010 18549781 1:CAS:528:DC%2BD1cXnvVSqsbY%3D 10.1016/j.neuron.2008.04.010
-
Jiang Q, Lee CY, Mandrekar S, Wilkinson B, Cramer P, Zelcer N, Mann K, Lamb B, Willson TM, Collins JL, Richardson JC, Smith JD, Comery TA, Riddell D, Holtzman DM, Tontonoz P, Landreth GE (2008) ApoE promotes the proteolytic degradation of Abeta. Neuron 58(5):681-693. doi: 10.1016/j.neuron.2008.04.010
-
(2008)
Neuron
, vol.58
, Issue.5
, pp. 681-693
-
-
Jiang, Q.1
Lee, C.Y.2
Mandrekar, S.3
Wilkinson, B.4
Cramer, P.5
Zelcer, N.6
Mann, K.7
Lamb, B.8
Willson, T.M.9
Collins, J.L.10
Richardson, J.C.11
Smith, J.D.12
Comery, T.A.13
Riddell, D.14
Holtzman, D.M.15
Tontonoz, P.16
Landreth, G.E.17
-
205
-
-
0036227542
-
Type 2 diabetes, APOE gene, and the risk for dementia and related pathologies: The Honolulu-Asia Aging Study
-
11916953 1:CAS:528:DC%2BD38Xis1Ois7Y%3D 10.2337/diabetes.51.4.1256
-
Peila R, Rodriguez BL, Launer LJ, Honolulu-Asia Aging S (2002) Type 2 diabetes, APOE gene, and the risk for dementia and related pathologies: the Honolulu-Asia Aging Study. Diabetes 51(4):1256-1262
-
(2002)
Diabetes
, vol.51
, Issue.4
, pp. 1256-1262
-
-
Peila, R.1
Rodriguez, B.L.2
Launer, L.J.3
Honolulu-Asia Aging, S.4
-
206
-
-
44649090171
-
Activation of the amyloid cascade in apolipoprotein E4 transgenic mice induces lysosomal activation and neurodegeneration resulting in marked cognitive deficits
-
10.1523/JNEUROSCI.5633-07.2008 1:CAS:528:DC%2BD1cXlvFWhtbw%3D 10.1523/JNEUROSCI.5633-07.2008
-
Belinson H, Lev D, Masliah E, Michaelson DM (2008) Activation of the amyloid cascade in apolipoprotein E4 transgenic mice induces lysosomal activation and neurodegeneration resulting in marked cognitive deficits. J Neurosci Off J Soc Neurosci 28(18):4690-4701. doi: 10.1523/JNEUROSCI.5633-07. 2008
-
(2008)
J Neurosci off J Soc Neurosci
, vol.28
, Issue.18
, pp. 4690-4701
-
-
Belinson, H.1
Lev, D.2
Masliah, E.3
Michaelson, D.M.4
-
207
-
-
12144290271
-
Neuron-specific apolipoprotein e4 proteolysis is associated with increased tau phosphorylation in brains of transgenic mice
-
10.1523/JNEUROSCI.4315-03.2004 1:CAS:528:DC%2BD2cXisVKhtr4%3D 10.1523/JNEUROSCI.4315-03.2004
-
Brecht WJ, Harris FM, Chang S, Tesseur I, Yu GQ, Xu Q, Dee Fish J, Wyss-Coray T, Buttini M, Mucke L, Mahley RW, Huang Y (2004) Neuron-specific apolipoprotein e4 proteolysis is associated with increased tau phosphorylation in brains of transgenic mice. J Neurosci Off J Soc Neurosci 24(10):2527-2534. doi: 10.1523/JNEUROSCI.4315-03.2004
-
(2004)
J Neurosci off J Soc Neurosci
, vol.24
, Issue.10
, pp. 2527-2534
-
-
Brecht, W.J.1
Harris, F.M.2
Chang, S.3
Tesseur, I.4
Yu, G.Q.5
Xu, Q.6
Dee Fish, J.7
Wyss-Coray, T.8
Buttini, M.9
Mucke, L.10
Mahley, R.W.11
Huang, Y.12
-
208
-
-
84862999162
-
Type 2 diabetes and cognitive impairment: Linking mechanisms
-
10.3233/JAD-2012-111433 22433668
-
Luchsinger JA (2012) Type 2 diabetes and cognitive impairment: linking mechanisms. J Alzheimers Dis 30:S185-S198. doi: 10.3233/JAD-2012-111433
-
(2012)
J Alzheimers Dis
, vol.30
-
-
Luchsinger, J.A.1
-
209
-
-
84859929415
-
Apolipoprotein e gene polymorphism: Effects on plasma lipids and risk of type 2 diabetes and coronary artery disease
-
10.1186/1475-2840-11-36 22520940 1:CAS:528:DC%2BC38XovFWitrk%3D 10.1186/1475-2840-11-36
-
Chaudhary R, Likidlilid A, Peerapatdit T, Tresukosol D, Srisuma S, Ratanamaneechat S, Sriratanasathavorn C (2012) Apolipoprotein E gene polymorphism: effects on plasma lipids and risk of type 2 diabetes and coronary artery disease. Cardiovasc Diabetol 11:36. doi: 10.1186/1475-2840-11-36
-
(2012)
Cardiovasc Diabetol
, vol.11
, pp. 36
-
-
Chaudhary, R.1
Likidlilid, A.2
Peerapatdit, T.3
Tresukosol, D.4
Srisuma, S.5
Ratanamaneechat, S.6
Sriratanasathavorn, C.7
-
210
-
-
0034085567
-
Cholesterol efflux regulatory protein, Tangier disease and familial high-density lipoprotein deficiency
-
10787172 1:CAS:528:DC%2BD3cXislWjs7c%3D 10.1097/00041433-200004000-00003
-
Hayden MR, Clee SM, Brooks-Wilson A, Genest J Jr, Attie A, Kastelein JJ (2000) Cholesterol efflux regulatory protein, Tangier disease and familial high-density lipoprotein deficiency. Curr Opin Lipidol 11(2):117-122
-
(2000)
Curr Opin Lipidol
, vol.11
, Issue.2
, pp. 117-122
-
-
Hayden, M.R.1
Clee, S.M.2
Brooks-Wilson, A.3
Genest, Jr.J.4
Attie, A.5
Kastelein, J.J.6
-
211
-
-
77953258151
-
The role of ATP-binding cassette transporter A1 in Alzheimer's disease and neurodegeneration
-
10.1016/j.bbalip.2010.02.010 20188211 1:CAS:528:DC%2BC3cXntlagsrY%3D 10.1016/j.bbalip.2010.02.010
-
Koldamova R, Fitz NF, Lefterov I (2010) The role of ATP-binding cassette transporter A1 in Alzheimer's disease and neurodegeneration. Biochim Biophys Acta 1801(8):824-830. doi: 10.1016/j.bbalip.2010.02.010
-
(2010)
Biochim Biophys Acta
, vol.1801
, Issue.8
, pp. 824-830
-
-
Koldamova, R.1
Fitz, N.F.2
Lefterov, I.3
-
212
-
-
4644295495
-
Deficiency of ABCA1 impairs apolipoprotein e metabolism in brain
-
10.1074/jbc.M407962200 15269218 1:CAS:528:DC%2BD2cXnslWms7o%3D 10.1074/jbc.M407962200
-
Hirsch-Reinshagen V, Zhou S, Burgess BL, Bernier L, McIsaac SA, Chan JY, Tansley GH, Cohn JS, Hayden MR, Wellington CL (2004) Deficiency of ABCA1 impairs apolipoprotein E metabolism in brain. J Biol Chem 279(39):41197-41207. doi: 10.1074/jbc.M407962200
-
(2004)
J Biol Chem
, vol.279
, Issue.39
, pp. 41197-41207
-
-
Hirsch-Reinshagen, V.1
Zhou, S.2
Burgess, B.L.3
Bernier, L.4
McIsaac, S.A.5
Chan, J.Y.6
Tansley, G.H.7
Cohn, J.S.8
Hayden, M.R.9
Wellington, C.L.10
-
213
-
-
84863678571
-
Tissue cholesterol content alterations in streptozotocin-induced diabetic rats
-
10.1038/aps.2012.50 22705727 1:CAS:528:DC%2BC38XpsFOqtrk%3D 10.1038/aps.2012.50
-
Wang XT, Li J, Liu L, Hu N, Jin S, Liu C, Mei D, Liu XD (2012) Tissue cholesterol content alterations in streptozotocin-induced diabetic rats. Acta Pharmacol Sin 33(7):909-917. doi: 10.1038/aps.2012.50
-
(2012)
Acta Pharmacol Sin
, vol.33
, Issue.7
, pp. 909-917
-
-
Wang, X.T.1
Li, J.2
Liu, L.3
Hu, N.4
Jin, S.5
Liu, C.6
Mei, D.7
Liu, X.D.8
-
214
-
-
39549105812
-
Prevention and promotion effects of apolipoprotein E4 on amylin aggregation
-
10.1016/j.bbrc.2008.01.103 18243137 1:CAS:528:DC%2BD1cXisVSqs74%3D 10.1016/j.bbrc.2008.01.103
-
Lei P, Wu WH, Li RW, Ma JW, Yu YP, Cui W, Zhao YF, Li YM (2008) Prevention and promotion effects of apolipoprotein E4 on amylin aggregation. Biochem Biophys Res Commun 368(2):414-418. doi: 10.1016/j.bbrc.2008.01.103
-
(2008)
Biochem Biophys Res Commun
, vol.368
, Issue.2
, pp. 414-418
-
-
Lei, P.1
Wu, W.H.2
Li, R.W.3
Ma, J.W.4
Yu, Y.P.5
Cui, W.6
Zhao, Y.F.7
Li, Y.M.8
-
215
-
-
57049143140
-
Mitochondria in neuroplasticity and neurological disorders
-
10.1016/j.neuron.2008.10.010 19081372 1:CAS:528:DC%2BD1cXhsFahs7rI 10.1016/j.neuron.2008.10.010
-
Mattson MP, Gleichmann M, Cheng A (2008) Mitochondria in neuroplasticity and neurological disorders. Neuron 60(5):748-766. doi: 10.1016/j.neuron.2008.10. 010
-
(2008)
Neuron
, vol.60
, Issue.5
, pp. 748-766
-
-
Mattson, M.P.1
Gleichmann, M.2
Cheng, A.3
-
216
-
-
67649687039
-
An integrative view of the role of oxidative stress, mitochondria and insulin in Alzheimer's disease
-
10.3233/JAD-2009-0972 19387110
-
Moreira PI, Duarte AI, Santos MS, Rego AC, Oliveira CR (2009) An integrative view of the role of oxidative stress, mitochondria and insulin in Alzheimer's disease. J Alzheimers Dis 16(4):741-761. doi: 10.3233/JAD-2009-0972
-
(2009)
J Alzheimers Dis
, vol.16
, Issue.4
, pp. 741-761
-
-
Moreira, P.I.1
Duarte, A.I.2
Santos, M.S.3
Rego, A.C.4
Oliveira, C.R.5
-
217
-
-
77951096150
-
Mitochondrial dynamics - Fusion, fission, movement, and mitophagy - In neurodegenerative diseases
-
10.1093/hmg/ddp326 19808793 1:CAS:528:DC%2BD1MXhtlCqu7nN 10.1093/hmg/ddp326
-
Chen H, Chan DC (2009) Mitochondrial dynamics - fusion, fission, movement, and mitophagy - in neurodegenerative diseases. Hum Mol Genet 18(R2):R169-R176. doi: 10.1093/hmg/ddp326
-
(2009)
Hum Mol Genet
, vol.18
, Issue.R2
-
-
Chen, H.1
Chan, D.C.2
-
218
-
-
70449469039
-
Reactive species and diabetes: Counteracting oxidative stress to improve health
-
10.1016/j.coph.2009.08.005 19766058 1:CAS:528:DC%2BD1MXhsVGqs7vL 10.1016/j.coph.2009.08.005
-
Perez-Matute P, Zulet MA, Martinez JA (2009) Reactive species and diabetes: counteracting oxidative stress to improve health. Curr Opin Pharmacol 9(6):771-779. doi: 10.1016/j.coph.2009.08.005
-
(2009)
Curr Opin Pharmacol
, vol.9
, Issue.6
, pp. 771-779
-
-
Perez-Matute, P.1
Zulet, M.A.2
Martinez, J.A.3
-
219
-
-
79954642381
-
Advances in metal-induced oxidative stress and human disease
-
10.1016/j.tox.2011.03.001 21414382 1:CAS:528:DC%2BC3MXltFemsrs%3D 10.1016/j.tox.2011.03.001
-
Jomova K, Valko M (2011) Advances in metal-induced oxidative stress and human disease. Toxicology 283(2-3):65-87. doi: 10.1016/j.tox.2011.03.001
-
(2011)
Toxicology
, vol.283
, Issue.2-3
, pp. 65-87
-
-
Jomova, K.1
Valko, M.2
-
220
-
-
79251603273
-
Hydrogen peroxide probes directed to different cellular compartments
-
10.1371/journal.pone.0014564 21283738 1:CAS:528:DC%2BC3MXhsFWit78%3D 10.1371/journal.pone.0014564
-
Malinouski M, Zhou Y, Belousov VV, Hatfield DL, Gladyshev VN (2011) Hydrogen peroxide probes directed to different cellular compartments. PLoS One 6(1):e14564. doi: 10.1371/journal.pone.0014564
-
(2011)
PLoS One
, vol.6
, Issue.1
, pp. 14564
-
-
Malinouski, M.1
Zhou, Y.2
Belousov, V.V.3
Hatfield, D.L.4
Gladyshev, V.N.5
-
221
-
-
69049113059
-
Ternary complexes of iron, amyloid-beta, and nitrilotriacetic acid: Binding affinities, redox properties, and relevance to iron-induced oxidative stress in Alzheimer's disease
-
10.1021/bi900907a 19601593 1:CAS:528:DC%2BD1MXpt1KjsrY%3D 10.1021/bi900907a
-
Jiang D, Li X, Williams R, Patel S, Men L, Wang Y, Zhou F (2009) Ternary complexes of iron, amyloid-beta, and nitrilotriacetic acid: binding affinities, redox properties, and relevance to iron-induced oxidative stress in Alzheimer's disease. Biochemistry 48(33):7939-7947. doi: 10.1021/bi900907a
-
(2009)
Biochemistry
, vol.48
, Issue.33
, pp. 7939-7947
-
-
Jiang, D.1
Li, X.2
Williams, R.3
Patel, S.4
Men, L.5
Wang, Y.6
Zhou, F.7
-
222
-
-
80052657317
-
Hydroxyl radical and its scavengers in health and disease
-
10.1155/2011/809696
-
Lipinski B (2011) Hydroxyl radical and its scavengers in health and disease. Oxidative Med Cell Longev 2011:809696. doi: 10.1155/2011/809696
-
(2011)
Oxidative Med Cell Longev
, vol.2011
, pp. 809696
-
-
Lipinski, B.1
-
223
-
-
33749986298
-
Free radicals and antioxidants in normal physiological functions and human disease
-
10.1016/j.biocel.2006.07.001 16978905 1:CAS:528:DC%2BD28XhtVygt7%2FF 10.1016/j.biocel.2006.07.001
-
Valko M, Leibfritz D, Moncol J, Cronin MT, Mazur M, Telser J (2007) Free radicals and antioxidants in normal physiological functions and human disease. Int J Biochem Cell Biol 39(1):44-84. doi: 10.1016/j.biocel.2006.07.001
-
(2007)
Int J Biochem Cell Biol
, vol.39
, Issue.1
, pp. 44-84
-
-
Valko, M.1
Leibfritz, D.2
Moncol, J.3
Cronin, M.T.4
Mazur, M.5
Telser, J.6
-
224
-
-
34249084004
-
Role of free radicals and antioxidants in health and disease
-
17535753 1:STN:280:DC%2BD2szitlGlsQ%3D%3D
-
Flora SJ (2007) Role of free radicals and antioxidants in health and disease. Cell Mol Biol 53(1):1-2
-
(2007)
Cell Mol Biol
, vol.53
, Issue.1
, pp. 1-2
-
-
Flora, S.J.1
-
225
-
-
77955917442
-
Oxidative stress in Alzheimer disease: A possibility for prevention
-
10.1016/j.neuropharm.2010.04.005 20394761 1:CAS:528:DC%2BC3cXhtVKhurfP 10.1016/j.neuropharm.2010.04.005
-
Bonda DJ, Wang X, Perry G, Nunomura A, Tabaton M, Zhu X, Smith MA (2010) Oxidative stress in Alzheimer disease: a possibility for prevention. Neuropharmacology 59(4-5):290-294. doi: 10.1016/j.neuropharm.2010.04.005
-
(2010)
Neuropharmacology
, vol.59
, Issue.4-5
, pp. 290-294
-
-
Bonda, D.J.1
Wang, X.2
Perry, G.3
Nunomura, A.4
Tabaton, M.5
Zhu, X.6
Smith, M.A.7
-
226
-
-
82755161992
-
The future of Alzheimer's disease: The next 10 years
-
German Task Force on Alzheimer's D 10.1016/j.pneurobio.2011.11.008 22137045 10.1016/j.pneurobio.2011.11.008
-
Hampel H, Prvulovic D, Teipel S, Jessen F, Luckhaus C, Frolich L, Riepe MW, Dodel R, Leyhe T, Bertram L, Hoffmann W, Faltraco F, German Task Force on Alzheimer's D (2011) The future of Alzheimer's disease: the next 10 years. Prog Neurobiol 95(4):718-728. doi: 10.1016/j.pneurobio.2011.11.008
-
(2011)
Prog Neurobiol
, vol.95
, Issue.4
, pp. 718-728
-
-
Hampel, H.1
Prvulovic, D.2
Teipel, S.3
Jessen, F.4
Luckhaus, C.5
Frolich, L.6
Riepe, M.W.7
Dodel, R.8
Leyhe, T.9
Bertram, L.10
Hoffmann, W.11
Faltraco, F.12
-
227
-
-
0033765735
-
Oxidative injury in diseases of the central nervous system: Focus on Alzheimer's disease
-
11063960 1:CAS:528:DC%2BD3cXns12msL0%3D 10.1016/S0002-9343(00)00547-7
-
Pratico D, Delanty N (2000) Oxidative injury in diseases of the central nervous system: focus on Alzheimer's disease. Am J Med 109(7):577-585
-
(2000)
Am J Med
, vol.109
, Issue.7
, pp. 577-585
-
-
Pratico, D.1
Delanty, N.2
-
228
-
-
84861851223
-
Brain glycogen-new perspectives on its metabolic function and regulation at the subcellular level
-
10.3389/fnene.2012.00003 1:CAS:528:DC%2BC38XltF2ltLY%3D 10.3389/fnene.2012.00003
-
Obel LF, Muller MS, Walls AB, Sickmann HM, Bak LK, Waagepetersen HS, Schousboe A (2012) Brain glycogen-new perspectives on its metabolic function and regulation at the subcellular level. Front Neuroenerg 4:3. doi: 10.3389/fnene.2012.00003
-
(2012)
Front Neuroenerg
, vol.4
, pp. 3
-
-
Obel, L.F.1
Muller, M.S.2
Walls, A.B.3
Sickmann, H.M.4
Bak, L.K.5
Waagepetersen, H.S.6
Schousboe, A.7
-
229
-
-
79959246028
-
Mitochondria, amyloid beta, and Alzheimer's disease
-
10.4061/2011/104545 21547208
-
Readnower RD, Sauerbeck AD, Sullivan PG (2011) Mitochondria, amyloid beta, and Alzheimer's disease. Int J Alzheimers Dis 2011:104545. doi: 10.4061/2011/104545
-
(2011)
Int J Alzheimers Dis
, vol.2011
, pp. 104545
-
-
Readnower, R.D.1
Sauerbeck, A.D.2
Sullivan, P.G.3
-
230
-
-
79251617521
-
Identification of the oxidative stress proteome in the brain
-
10.1016/j.freeradbiomed.2010.11.021 21111808 1:CAS:528: DC%2BC3MXhtlahsbo%3D 10.1016/j.freeradbiomed.2010.11.021
-
Sultana R, Butterfield DA (2011) Identification of the oxidative stress proteome in the brain. Free Radic Biol Med 50(4):487-494. doi: 10.1016/j.freeradbiomed.2010.11.021
-
(2011)
Free Radic Biol Med
, vol.50
, Issue.4
, pp. 487-494
-
-
Sultana, R.1
Butterfield, D.A.2
-
231
-
-
0034937703
-
Detection of nitrotyrosine in the diabetic plasma: Evidence of oxidative stress
-
10.1007/s001250100529 11508267 1:CAS:528:DC%2BD3MXks1Ort7o%3D 10.1007/s001250100529
-
Ceriello A, Mercuri F, Quagliaro L, Assaloni R, Motz E, Tonutti L, Taboga C (2001) Detection of nitrotyrosine in the diabetic plasma: evidence of oxidative stress. Diabetologia 44(7):834-838. doi: 10.1007/s001250100529
-
(2001)
Diabetologia
, vol.44
, Issue.7
, pp. 834-838
-
-
Ceriello, A.1
Mercuri, F.2
Quagliaro, L.3
Assaloni, R.4
Motz, E.5
Tonutti, L.6
Taboga, C.7
-
232
-
-
84859082257
-
Endothelial-specific Nox2 overexpression increases vascular superoxide and macrophage recruitment in ApoE(-)/(-) mice
-
10.1093/cvr/cvs026 22287576 1:CAS:528:DC%2BC38Xks1Sgsb8%3D 10.1093/cvr/cvs026
-
Douglas G, Bendall JK, Crabtree MJ, Tatham AL, Carter EE, Hale AB, Channon KM (2012) Endothelial-specific Nox2 overexpression increases vascular superoxide and macrophage recruitment in ApoE(-)/(-) mice. Cardiovasc Res 94(1):20-29. doi: 10.1093/cvr/cvs026
-
(2012)
Cardiovasc Res
, vol.94
, Issue.1
, pp. 20-29
-
-
Douglas, G.1
Bendall, J.K.2
Crabtree, M.J.3
Tatham, A.L.4
Carter, E.E.5
Hale, A.B.6
Channon, K.M.7
-
233
-
-
33645765312
-
Diabetes and mitochondrial function: Role of hyperglycemia and oxidative stress
-
10.1016/j.taap.2006.01.003 16490224 1:CAS:528:DC%2BD28Xjs1Gmt7w%3D 10.1016/j.taap.2006.01.003
-
Rolo AP, Palmeira CM (2006) Diabetes and mitochondrial function: role of hyperglycemia and oxidative stress. Toxicol Appl Pharmacol 212(2):167-178. doi: 10.1016/j.taap.2006.01.003
-
(2006)
Toxicol Appl Pharmacol
, vol.212
, Issue.2
, pp. 167-178
-
-
Rolo, A.P.1
Palmeira, C.M.2
-
234
-
-
84872532360
-
Abnormal mitochondrial dynamics in the pathogenesis of Alzheimer's disease
-
doi: 10.3233/JAD-2012-129005
-
Zhu X, Perry G, Smith MA, Wang X (2012) Abnormal mitochondrial dynamics in the pathogenesis of Alzheimer's disease. J Alzheimers Dis. doi: 10.3233/JAD-2012-129005
-
(2012)
J Alzheimers Dis
-
-
Zhu, X.1
Perry, G.2
Smith, M.A.3
Wang, X.4
-
235
-
-
25444469412
-
Mitochondrial metabolism of reactive oxygen species
-
1:CAS:528:DC%2BD2MXislamsbc%3D 10.1007/s10541-005-0102-7
-
Andreyev AY, Kushnareva YE, Starkov AA (2005) Mitochondrial metabolism of reactive oxygen species. Biochem Biokhim 70(2):200-214
-
(2005)
Biochem Biokhim
, vol.70
, Issue.2
, pp. 200-214
-
-
Andreyev, A.Y.1
Kushnareva, Y.E.2
Starkov, A.A.3
-
236
-
-
77952541558
-
The sites and topology of mitochondrial superoxide production
-
10.1016/j.exger.2010.01.003 20064600 1:CAS:528:DC%2BC3cXmslGjt70%3D 10.1016/j.exger.2010.01.003
-
Brand MD (2010) The sites and topology of mitochondrial superoxide production. Exp Gerontol 45(7-8):466-472. doi: 10.1016/j.exger.2010.01.003
-
(2010)
Exp Gerontol
, vol.45
, Issue.7-8
, pp. 466-472
-
-
Brand, M.D.1
-
237
-
-
58249093939
-
How mitochondria produce reactive oxygen species
-
10.1042/BJ20081386 19061483 1:CAS:528:DC%2BD1cXhsV2lt77F 10.1042/BJ20081386
-
Murphy MP (2009) How mitochondria produce reactive oxygen species. Biochem J 417(1):1-13. doi: 10.1042/BJ20081386
-
(2009)
Biochem J
, vol.417
, Issue.1
, pp. 1-13
-
-
Murphy, M.P.1
-
238
-
-
79953667930
-
Reactive oxygen species production by forward and reverse electron fluxes in the mitochondrial respiratory chain
-
10.1371/journal.pcbi.1001115 21483483 1:CAS:528:DC%2BC3MXkvVeqsr8%3D 10.1371/journal.pcbi.1001115
-
Selivanov VA, Votyakova TV, Pivtoraiko VN, Zeak J, Sukhomlin T, Trucco M, Roca J, Cascante M (2011) Reactive oxygen species production by forward and reverse electron fluxes in the mitochondrial respiratory chain. PLoS Comput Biol 7(3):e1001115. doi: 10.1371/journal.pcbi.1001115
-
(2011)
PLoS Comput Biol
, vol.7
, Issue.3
, pp. 1001115
-
-
Selivanov, V.A.1
Votyakova, T.V.2
Pivtoraiko, V.N.3
Zeak, J.4
Sukhomlin, T.5
Trucco, M.6
Roca, J.7
Cascante, M.8
-
239
-
-
84863842930
-
Hypoxic-ischemic injury in the developing brain: The role of reactive oxygen species originating in mitochondria
-
10.1155/2012/542976 22548167
-
Ten VS, Starkov A (2012) Hypoxic-ischemic injury in the developing brain: the role of reactive oxygen species originating in mitochondria. Neurol Res Int 2012:542976. doi: 10.1155/2012/542976
-
(2012)
Neurol Res Int
, vol.2012
, pp. 542976
-
-
Ten, V.S.1
Starkov, A.2
-
240
-
-
84868286870
-
New insights in the amyloid-beta interaction with mitochondria
-
10.1155/2012/324968 22523685
-
Spuch C, Ortolano S, Navarro C (2012) New insights in the amyloid-beta interaction with mitochondria. J Aging Res 2012:324968. doi: 10.1155/2012/324968
-
(2012)
J Aging Res
, vol.2012
, pp. 324968
-
-
Spuch, C.1
Ortolano, S.2
Navarro, C.3
-
241
-
-
84870299231
-
Nitric oxide-mediated oxidative damage and the progressive demise of motor neurons in ALS
-
doi: 10.1007/s12640-012-9322-y
-
Drechsel DA, Estevez AG, Barbeito L, Beckman JS (2012) Nitric oxide-mediated oxidative damage and the progressive demise of motor neurons in ALS. Neurotox Res. doi: 10.1007/s12640-012-9322-y
-
(2012)
Neurotox Res
-
-
Drechsel, D.A.1
Estevez, A.G.2
Barbeito, L.3
Beckman, J.S.4
-
242
-
-
75149152568
-
Increased iron and free radical generation in preclinical Alzheimer disease and mild cognitive impairment
-
10.3233/JAD-2010-1239 20061651
-
Smith MA, Zhu X, Tabaton M, Liu G, McKeel DW Jr, Cohen ML, Wang X, Siedlak SL, Dwyer BE, Hayashi T, Nakamura M, Nunomura A, Perry G (2010) Increased iron and free radical generation in preclinical Alzheimer disease and mild cognitive impairment. J Alzheimers Dis 19(1):363-372. doi: 10.3233/JAD-2010-1239
-
(2010)
J Alzheimers Dis
, vol.19
, Issue.1
, pp. 363-372
-
-
Smith, M.A.1
Zhu, X.2
Tabaton, M.3
Liu, G.4
McKeel, Jr.D.W.5
Cohen, M.L.6
Wang, X.7
Siedlak, S.L.8
Dwyer, B.E.9
Hayashi, T.10
Nakamura, M.11
Nunomura, A.12
Perry, G.13
-
243
-
-
80054978676
-
Circulating biomarkers of protein oxidation for Alzheimer disease: Expectations within limits
-
10.1016/j.bbapap.2011.10.001 22019699 10.1016/j.bbapap.2011.10.001 1:CAS:528:DC%2BC3MXhsFSjtb7P
-
Di Domenico F, Coccia R, Butterfield DA, Perluigi M (2011) Circulating biomarkers of protein oxidation for Alzheimer disease: expectations within limits. Biochim Biophys Acta 1814(12):1785-1795. doi: 10.1016/j.bbapap.2011.10. 001
-
(2011)
Biochim Biophys Acta
, vol.1814
, Issue.12
, pp. 1785-1795
-
-
Di Domenico, F.1
Coccia, R.2
Butterfield, D.A.3
Perluigi, M.4
-
244
-
-
83155183308
-
Inhibition of the mitochondrial enzyme ABAD restores the amyloid-beta-mediated deregulation of estradiol
-
10.1371/journal.pone.0028887 22174920 1:CAS:528:DC%2BC38XoslKj 10.1371/journal.pone.0028887
-
Lim YA, Grimm A, Giese M, Mensah-Nyagan AG, Villafranca JE, Ittner LM, Eckert A, Gotz J (2011) Inhibition of the mitochondrial enzyme ABAD restores the amyloid-beta-mediated deregulation of estradiol. PLoS One 6(12):e28887. doi: 10.1371/journal.pone.0028887
-
(2011)
PLoS One
, vol.6
, Issue.12
, pp. 28887
-
-
Lim, Y.A.1
Grimm, A.2
Giese, M.3
Mensah-Nyagan, A.G.4
Villafranca, J.E.5
Ittner, L.M.6
Eckert, A.7
Gotz, J.8
-
245
-
-
11144353586
-
ABAD directly links Abeta to mitochondrial toxicity in Alzheimer's disease
-
10.1126/science.1091230 15087549 1:CAS:528:DC%2BD2cXjtVWksrg%3D 10.1126/science.1091230
-
Lustbader JW, Cirilli M, Lin C, Xu HW, Takuma K, Wang N, Caspersen C, Chen X, Pollak S, Chaney M, Trinchese F, Liu S, Gunn-Moore F, Lue LF, Walker DG, Kuppusamy P, Zewier ZL, Arancio O, Stern D, Yan SS, Wu H (2004) ABAD directly links Abeta to mitochondrial toxicity in Alzheimer's disease. Science 304(5669):448-452. doi: 10.1126/science.1091230
-
(2004)
Science
, vol.304
, Issue.5669
, pp. 448-452
-
-
Lustbader, J.W.1
Cirilli, M.2
Lin, C.3
Xu, H.W.4
Takuma, K.5
Wang, N.6
Caspersen, C.7
Chen, X.8
Pollak, S.9
Chaney, M.10
Trinchese, F.11
Liu, S.12
Gunn-Moore, F.13
Lue, L.F.14
Walker, D.G.15
Kuppusamy, P.16
Zewier, Z.L.17
Arancio, O.18
Stern, D.19
Yan, S.S.20
Wu, H.21
more..
-
246
-
-
0034684963
-
Fibrillar islet amyloid polypeptide differentially affects oxidative mechanisms and lipoprotein uptake in correlation with cytotoxicity in two insulin-producing cell lines
-
10.1006/bbrc.1999.1989 10631112 1:CAS:528:DC%2BD3cXisFertA%3D%3D 10.1006/bbrc.1999.1989
-
Janciauskiene S, Ahren B (2000) Fibrillar islet amyloid polypeptide differentially affects oxidative mechanisms and lipoprotein uptake in correlation with cytotoxicity in two insulin-producing cell lines. Biochem Biophys Res Commun 267(2):619-625. doi: 10.1006/bbrc.1999.1989
-
(2000)
Biochem Biophys Res Commun
, vol.267
, Issue.2
, pp. 619-625
-
-
Janciauskiene, S.1
Ahren, B.2
-
247
-
-
26244433460
-
Thiol reducing compounds prevent human amylin-evoked cytotoxicity
-
10.1111/j.1742-4658.2005.04903.x 16176268 1:CAS:528:DC%2BD2MXhtV2gt7jE 10.1111/j.1742-4658.2005.04903.x
-
Konarkowska B, Aitken JF, Kistler J, Zhang S, Cooper GJ (2005) Thiol reducing compounds prevent human amylin-evoked cytotoxicity. FEBS J 272(19):4949-4959. doi: 10.1111/j.1742-4658.2005.04903.x
-
(2005)
FEBS J
, vol.272
, Issue.19
, pp. 4949-4959
-
-
Konarkowska, B.1
Aitken, J.F.2
Kistler, J.3
Zhang, S.4
Cooper, G.J.5
-
248
-
-
78649454844
-
Proteomics reveals novel oxidative and glycolytic mechanisms in type 1 diabetic patients' skin which are normalized by kidney-pancreas transplantation
-
10.1371/journal.pone.0009923 20360867 10.1371/journal.pone.0009923 1:CAS:528:DC%2BC3cXktlWgtbo%3D
-
Folli F, Guzzi V, Perego L, Coletta DK, Finzi G, Placidi C, La Rosa S, Capella C, Socci C, Lauro D, Tripathy D, Jenkinson C, Paroni R, Orsenigo E, Cighetti G, Gregorini L, Staudacher C, Secchi A, Bachi A, Brownlee M, Fiorina P (2010) Proteomics reveals novel oxidative and glycolytic mechanisms in type 1 diabetic patients' skin which are normalized by kidney-pancreas transplantation. PLoS One 5(3):e9923. doi: 10.1371/journal.pone.0009923
-
(2010)
PLoS One
, vol.5
, Issue.3
, pp. 9923
-
-
Folli, F.1
Guzzi, V.2
Perego, L.3
Coletta, D.K.4
Finzi, G.5
Placidi, C.6
La Rosa, S.7
Capella, C.8
Socci, C.9
Lauro, D.10
Tripathy, D.11
Jenkinson, C.12
Paroni, R.13
Orsenigo, E.14
Cighetti, G.15
Gregorini, L.16
Staudacher, C.17
Secchi, A.18
Bachi, A.19
Brownlee, M.20
Fiorina, P.21
more..
-
249
-
-
78049285332
-
Maillard reaction of ribose 5-phosphate generates superoxide and glycation products for bovine heart cytochrome c reduction
-
10.1016/j.carres.2010.09.013 20933223 1:CAS:528:DC%2BC3cXhtlent7%2FE 10.1016/j.carres.2010.09.013
-
Gersten RA, Gretebeck LM, Hildick-Smith G, Sandwick RK (2010) Maillard reaction of ribose 5-phosphate generates superoxide and glycation products for bovine heart cytochrome c reduction. Carbohydr Res 345(17):2499-2506. doi: 10.1016/j.carres.2010.09.013
-
(2010)
Carbohydr Res
, vol.345
, Issue.17
, pp. 2499-2506
-
-
Gersten, R.A.1
Gretebeck, L.M.2
Hildick-Smith, G.3
Sandwick, R.K.4
-
250
-
-
84864282827
-
Cell oxidant stress delivery and cell dysfunction onset in type 2 diabetes
-
10.1016/j.biochi.2012.01.020 22333037 1:CAS:528:DC%2BC38XptVKltbk%3D 10.1016/j.biochi.2012.01.020
-
Kassab A, Piwowar A (2012) Cell oxidant stress delivery and cell dysfunction onset in type 2 diabetes. Biochimie 94(9):1837-1848. doi: 10.1016/j.biochi.2012.01.020
-
(2012)
Biochimie
, vol.94
, Issue.9
, pp. 1837-1848
-
-
Kassab, A.1
Piwowar, A.2
-
251
-
-
63049127020
-
Mitochondrial superoxide plays a crucial role in the development of mitochondrial dysfunction during high glucose exposure in rat renal proximal tubular cells
-
10.1016/j.freeradbiomed.2009.01.022 19439219 1:CAS:528: DC%2BD1MXkt1Shtb8%3D 10.1016/j.freeradbiomed.2009.01.022
-
Munusamy S, MacMillan-Crow LA (2009) Mitochondrial superoxide plays a crucial role in the development of mitochondrial dysfunction during high glucose exposure in rat renal proximal tubular cells. Free Radic Biol Med 46(8):1149-1157. doi: 10.1016/j.freeradbiomed.2009.01.022
-
(2009)
Free Radic Biol Med
, vol.46
, Issue.8
, pp. 1149-1157
-
-
Munusamy, S.1
MacMillan-Crow, L.A.2
-
252
-
-
28844462418
-
Role of poly(ADP-ribose) polymerase-1 activation in the pathogenesis of diabetic complications: Endothelial dysfunction, as a common underlying theme
-
10.1089/ars.2005.7.1568 16356120 1:CAS:528:DC%2BD2MXhtlWht7%2FJ 10.1089/ars.2005.7.1568
-
Pacher P, Szabo C (2005) Role of poly(ADP-ribose) polymerase-1 activation in the pathogenesis of diabetic complications: endothelial dysfunction, as a common underlying theme. Antioxid Redox Signal 7(11-12):1568-1580. doi: 10.1089/ars.2005.7.1568
-
(2005)
Antioxid Redox Signal
, vol.7
, Issue.11-12
, pp. 1568-1580
-
-
Pacher, P.1
Szabo, C.2
-
253
-
-
79951571474
-
Mitochondrial membrane potential probes and the proton gradient: A practical usage guide
-
10.2144/000113610 21486251 1:CAS:528:DC%2BC3MXhvFGrtb0%3D 10.2144/000113610
-
Perry SW, Norman JP, Barbieri J, Brown EB, Gelbard HA (2011) Mitochondrial membrane potential probes and the proton gradient: a practical usage guide. Biotechniques 50(2):98-115. doi: 10.2144/000113610
-
(2011)
Biotechniques
, vol.50
, Issue.2
, pp. 98-115
-
-
Perry, S.W.1
Norman, J.P.2
Barbieri, J.3
Brown, E.B.4
Gelbard, H.A.5
-
254
-
-
1442349997
-
Uncoupling proteins prevent glucose-induced neuronal oxidative stress and programmed cell death
-
14988258 1:CAS:528:DC%2BD2cXhvFeksr0%3D 10.2337/diabetes.53.3.726
-
Vincent AM, Olzmann JA, Brownlee M, Sivitz WI, Russell JW (2004) Uncoupling proteins prevent glucose-induced neuronal oxidative stress and programmed cell death. Diabetes 53(3):726-734
-
(2004)
Diabetes
, vol.53
, Issue.3
, pp. 726-734
-
-
Vincent, A.M.1
Olzmann, J.A.2
Brownlee, M.3
Sivitz, W.I.4
Russell, J.W.5
-
255
-
-
27644437944
-
Oxidative and nitrosative stress in brain mitochondria of diabetic rats
-
10.1677/joe.1.06269 16214939 1:CAS:528:DC%2BD2MXhtF2itLrL 10.1677/joe.1.06269
-
Mastrocola R, Restivo F, Vercellinatto I, Danni O, Brignardello E, Aragno M, Boccuzzi G (2005) Oxidative and nitrosative stress in brain mitochondria of diabetic rats. J Endocrinol 187(1):37-44. doi: 10.1677/joe.1.06269
-
(2005)
J Endocrinol
, vol.187
, Issue.1
, pp. 37-44
-
-
Mastrocola, R.1
Restivo, F.2
Vercellinatto, I.3
Danni, O.4
Brignardello, E.5
Aragno, M.6
Boccuzzi, G.7
-
256
-
-
79953276927
-
Impact of STZ-induced hyperglycemia and insulin-induced hypoglycemia in plasma amino acids and cortical synaptosomal neurotransmitters
-
10.1002/syn.20863 20853444 1:CAS:528:DC%2BC3MXktFeksr0%3D 10.1002/syn.20863
-
Cardoso S, Carvalho C, Santos R, Correia S, Santos MS, Seica R, Oliveira CR, Moreira PI (2011) Impact of STZ-induced hyperglycemia and insulin-induced hypoglycemia in plasma amino acids and cortical synaptosomal neurotransmitters. Synapse 65(6):457-466. doi: 10.1002/syn.20863
-
(2011)
Synapse
, vol.65
, Issue.6
, pp. 457-466
-
-
Cardoso, S.1
Carvalho, C.2
Santos, R.3
Correia, S.4
Santos, M.S.5
Seica, R.6
Oliveira, C.R.7
Moreira, P.I.8
-
257
-
-
79957845530
-
Impaired mitochondrial respiratory functions and oxidative stress in streptozotocin-induced diabetic rats
-
10.3390/ijms12053133 21686174 1:CAS:528:DC%2BC3MXmsV2it70%3D 10.3390/ijms12053133
-
Raza H, Prabu SK, John A, Avadhani NG (2011) Impaired mitochondrial respiratory functions and oxidative stress in streptozotocin-induced diabetic rats. Int J Mol Sci 12(5):3133-3147. doi: 10.3390/ijms12053133
-
(2011)
Int J Mol Sci
, vol.12
, Issue.5
, pp. 3133-3147
-
-
Raza, H.1
Prabu, S.K.2
John, A.3
Avadhani, N.G.4
-
258
-
-
78349297565
-
Oxidative stress and diabetic complications
-
10.1161/CIRCRESAHA.110.223545 21030723 1:CAS:528:DC%2BC3cXhtlGjsrrP 10.1161/CIRCRESAHA.110.223545
-
Giacco F, Brownlee M (2010) Oxidative stress and diabetic complications. Circ Res 107(9):1058-1070. doi: 10.1161/CIRCRESAHA.110.223545
-
(2010)
Circ Res
, vol.107
, Issue.9
, pp. 1058-1070
-
-
Giacco, F.1
Brownlee, M.2
-
259
-
-
79952785518
-
Advanced glycation endproducts as gerontotoxins and biomarkers for carbonyl-based degenerative processes in Alzheimer's disease
-
10.1515/CCLM.2011.079 21275816 1:CAS:528:DC%2BC3MXms1Wnu7o%3D 10.1515/cclm.2011.079
-
Rahmadi A, Steiner N, Munch G (2011) Advanced glycation endproducts as gerontotoxins and biomarkers for carbonyl-based degenerative processes in Alzheimer's disease. Clin Chem Lab Med 49(3):385-391. doi: 10.1515/CCLM.2011.079
-
(2011)
Clin Chem Lab Med
, vol.49
, Issue.3
, pp. 385-391
-
-
Rahmadi, A.1
Steiner, N.2
Munch, G.3
-
260
-
-
84881624747
-
Advanced glycation end products
-
10.1159/000324945 21659759 1:CAS:528:DC%2BC38XlsFWjtQ%3D%3D 10.1159/000324945
-
Thomas MC (2011) Advanced glycation end products. Contrib Nephrol 170:66-74. doi: 10.1159/000324945
-
(2011)
Contrib Nephrol
, vol.170
, pp. 66-74
-
-
Thomas, M.C.1
-
261
-
-
45549104269
-
Oxidative stress stimulates skeletal muscle glucose uptake through a phosphatidylinositol 3-kinase-dependent pathway
-
10.1152/ajpendo.00150.2007 18303121 1:CAS:528:DC%2BD1cXlvFCju7o%3D 10.1152/ajpendo.00150.2007
-
Higaki Y, Mikami T, Fujii N, Hirshman MF, Koyama K, Seino T, Tanaka K, Goodyear LJ (2008) Oxidative stress stimulates skeletal muscle glucose uptake through a phosphatidylinositol 3-kinase-dependent pathway. Am J Physiol Endocrinol Metab 294(5):E889-E897. doi: 10.1152/ajpendo.00150.2007
-
(2008)
Am J Physiol Endocrinol Metab
, vol.294
, Issue.5
-
-
Higaki, Y.1
Mikami, T.2
Fujii, N.3
Hirshman, M.F.4
Koyama, K.5
Seino, T.6
Tanaka, K.7
Goodyear, L.J.8
-
262
-
-
77953307362
-
Oxidative stress, nitric oxide, and diabetes
-
10.1900/RDS.2010.7.15 20703435 10.1900/RDS.2010.7.15
-
Pitocco D, Zaccardi F, Di Stasio E, Romitelli F, Santini SA, Zuppi C, Ghirlanda G (2010) Oxidative stress, nitric oxide, and diabetes. Rev Diabet Stud 7(1):15-25. doi: 10.1900/RDS.2010.7.15
-
(2010)
Rev Diabet Stud
, vol.7
, Issue.1
, pp. 15-25
-
-
Pitocco, D.1
Zaccardi, F.2
Di Stasio, E.3
Romitelli, F.4
Santini, S.A.5
Zuppi, C.6
Ghirlanda, G.7
-
263
-
-
0035672506
-
Oxidative stress impairs nuclear proteins binding to the insulin responsive element in the GLUT4 promoter
-
10.1007/s001250100024 11793016 1:CAS:528:DC%2BD3MXovFWit7k%3D 10.1007/s001250100024
-
Pessler D, Rudich A, Bashan N (2001) Oxidative stress impairs nuclear proteins binding to the insulin responsive element in the GLUT4 promoter. Diabetologia 44(12):2156-2164. doi: 10.1007/s001250100024
-
(2001)
Diabetologia
, vol.44
, Issue.12
, pp. 2156-2164
-
-
Pessler, D.1
Rudich, A.2
Bashan, N.3
-
264
-
-
0142091454
-
Ceramide disables 3-phosphoinositide binding to the pleckstrin homology domain of protein kinase B (PKB)/Akt by a PKCzeta-dependent mechanism
-
14560023 1:CAS:528:DC%2BD3sXosFOgt7k%3D 10.1128/MCB.23.21.7794-7808.2003
-
Powell DJ, Hajduch E, Kular G, Hundal HS (2003) Ceramide disables 3-phosphoinositide binding to the pleckstrin homology domain of protein kinase B (PKB)/Akt by a PKCzeta-dependent mechanism. Mol Cell Biol 23(21):7794-7808
-
(2003)
Mol Cell Biol
, vol.23
, Issue.21
, pp. 7794-7808
-
-
Powell, D.J.1
Hajduch, E.2
Kular, G.3
Hundal, H.S.4
-
265
-
-
80053291126
-
Dietary lipids and their oxidized products in Alzheimer's disease
-
10.1002/mnfr.201100208 21954186 1:CAS:528:DC%2BC38XmsFagtA%3D%3D 10.1002/mnfr.201100208
-
Corsinovi L, Biasi F, Poli G, Leonarduzzi G, Isaia G (2011) Dietary lipids and their oxidized products in Alzheimer's disease. Mol Nutr Food Res 55(Suppl 2):S161-S172. doi: 10.1002/mnfr.201100208
-
(2011)
Mol Nutr Food Res
, vol.55
, Issue.SUPPL. 2
-
-
Corsinovi, L.1
Biasi, F.2
Poli, G.3
Leonarduzzi, G.4
Isaia, G.5
-
266
-
-
80755187946
-
Oxidative stress and diabetes mellitus
-
10.1515/CCLM.2011.250 1:CAS:528:DC%2BC38XlslyqtQ%3D%3D
-
Yang H, Jin X, Kei Lam CW, Yan SK (2011) Oxidative stress and diabetes mellitus. Clin Chem Lab Med CCLM/FESCC 49(11):1773-1782. doi: 10.1515/CCLM.2011.250
-
(2011)
Clin Chem Lab Med CCLM/FESCC
, vol.49
, Issue.11
, pp. 1773-1782
-
-
Yang, H.1
Jin, X.2
Kei Lam, C.W.3
Yan, S.K.4
-
267
-
-
84866862372
-
Redox proteomics in selected neurodegenerative disorders: From its infancy to future applications
-
doi: 10.1089/ars.2011.4109
-
Butterfield DA, Perluigi M, Reed T, Muharib T, Hughes CP, Robinson RA, Sultana R (2012) Redox proteomics in selected neurodegenerative disorders: from its infancy to future applications. Antioxid Redox Signal. doi: 10.1089/ars.2011.4109
-
(2012)
Antioxid Redox Signal
-
-
Butterfield, D.A.1
Perluigi, M.2
Reed, T.3
Muharib, T.4
Hughes, C.P.5
Robinson, R.A.6
Sultana, R.7
-
268
-
-
78049441228
-
Oxysterols: A world to explore
-
10.1016/j.fct.2010.09.023 1:CAS:528:DC%2BC3cXhtlKrs7rL
-
Otaegui-Arrazola A, Menendez-Carreno M, Ansorena D, Astiasaran I (2010) Oxysterols: a world to explore. Food Chem Toxicol Int J Publ Br Ind Biol Res Assoc 48(12):3289-3303. doi: 10.1016/j.fct.2010.09.023
-
(2010)
Food Chem Toxicol Int J Publ Br Ind Biol Res Assoc
, vol.48
, Issue.12
, pp. 3289-3303
-
-
Otaegui-Arrazola, A.1
Menendez-Carreno, M.2
Ansorena, D.3
Astiasaran, I.4
-
269
-
-
65649083410
-
Cholesterol oxidation products and disease: An emerging topic of interest in medicinal chemistry
-
19199932 1:CAS:528:DC%2BD1MXjsFGqtr8%3D 10.2174/092986709787458353
-
Sottero B, Gamba P, Gargiulo S, Leonarduzzi G, Poli G (2009) Cholesterol oxidation products and disease: an emerging topic of interest in medicinal chemistry. Curr Med Chem 16(6):685-705
-
(2009)
Curr Med Chem
, vol.16
, Issue.6
, pp. 685-705
-
-
Sottero, B.1
Gamba, P.2
Gargiulo, S.3
Leonarduzzi, G.4
Poli, G.5
-
270
-
-
34249828178
-
Regulation of alpha- and beta-secretase activity by oxysterols: Cerebrosterol stimulates processing of APP via the alpha-secretase pathway
-
10.1016/j.bbrc.2007.05.033 17532301 1:CAS:528:DC%2BD2sXmtFKqtLs%3D 10.1016/j.bbrc.2007.05.033
-
Famer D, Meaney S, Mousavi M, Nordberg A, Bjorkhem I, Crisby M (2007) Regulation of alpha- and beta-secretase activity by oxysterols: cerebrosterol stimulates processing of APP via the alpha-secretase pathway. Biochem Biophys Res Commun 359(1):46-50. doi: 10.1016/j.bbrc.2007.05.033
-
(2007)
Biochem Biophys Res Commun
, vol.359
, Issue.1
, pp. 46-50
-
-
Famer, D.1
Meaney, S.2
Mousavi, M.3
Nordberg, A.4
Bjorkhem, I.5
Crisby, M.6
-
271
-
-
56449108741
-
Regulation of brain polyunsaturated fatty acid uptake and turnover
-
10.1016/j.plefa.2008.09.003 1:CAS:528:DC%2BD1cXhsVGhtb7M 10.1016/j.plefa.2008.09.003
-
Chen CT, Green JT, Orr SK, Bazinet RP (2008) Regulation of brain polyunsaturated fatty acid uptake and turnover. Prostaglandins Leukot Essent Fat Acids 79(3-5):85-91. doi: 10.1016/j.plefa.2008.09.003
-
(2008)
Prostaglandins Leukot Essent Fat Acids
, vol.79
, Issue.3-5
, pp. 85-91
-
-
Chen, C.T.1
Green, J.T.2
Orr, S.K.3
Bazinet, R.P.4
-
272
-
-
67349099567
-
The essential role of lipids in Alzheimer's disease
-
10.1016/j.biochi.2009.03.004 19303044 1:CAS:528:DC%2BD1MXmtVCjtb4%3D 10.1016/j.biochi.2009.03.004
-
Florent-Bechard S, Desbene C, Garcia P, Allouche A, Youssef I, Escanye MC, Koziel V, Hanse M, Malaplate-Armand C, Stenger C, Kriem B, Yen-Potin FT, Olivier JL, Pillot T, Oster T (2009) The essential role of lipids in Alzheimer's disease. Biochimie 91(6):804-809. doi: 10.1016/j.biochi.2009.03.004
-
(2009)
Biochimie
, vol.91
, Issue.6
, pp. 804-809
-
-
Florent-Bechard, S.1
Desbene, C.2
Garcia, P.3
Allouche, A.4
Youssef, I.5
Escanye, M.C.6
Koziel, V.7
Hanse, M.8
Malaplate-Armand, C.9
Stenger, C.10
Kriem, B.11
Yen-Potin, F.T.12
Olivier, J.L.13
Pillot, T.14
Oster, T.15
-
273
-
-
47049095632
-
Routes to 4-hydroxynonenal: Fundamental issues in the mechanisms of lipid peroxidation
-
10.1074/jbc.R800001200 18285327 1:CAS:528:DC%2BD1cXmsFekt7g%3D 10.1074/jbc.R800001200
-
Schneider C, Porter NA, Brash AR (2008) Routes to 4-hydroxynonenal: fundamental issues in the mechanisms of lipid peroxidation. J Biol Chem 283(23):15539-15543. doi: 10.1074/jbc.R800001200
-
(2008)
J Biol Chem
, vol.283
, Issue.23
, pp. 15539-15543
-
-
Schneider, C.1
Porter, N.A.2
Brash, A.R.3
-
274
-
-
77956567906
-
Advances in methods for the determination of biologically relevant lipid peroxidation products
-
10.3109/10715762.2010.498476 20836661 1:CAS:528:DC%2BC3cXhtFCrt7fP 10.3109/10715762.2010.498476
-
Spickett CM, Wiswedel I, Siems W, Zarkovic K, Zarkovic N (2010) Advances in methods for the determination of biologically relevant lipid peroxidation products. Free Radic Res 44(10):1172-1202. doi: 10.3109/10715762.2010.498476
-
(2010)
Free Radic Res
, vol.44
, Issue.10
, pp. 1172-1202
-
-
Spickett, C.M.1
Wiswedel, I.2
Siems, W.3
Zarkovic, K.4
Zarkovic, N.5
-
275
-
-
27644446857
-
Lipid peroxidation is an early event in the brain in amnestic mild cognitive impairment
-
10.1002/ana.20629 16240347 1:CAS:528:DC%2BD2MXht1Cgu73F 10.1002/ana.20629
-
Markesbery WR, Kryscio RJ, Lovell MA, Morrow JD (2005) Lipid peroxidation is an early event in the brain in amnestic mild cognitive impairment. Ann Neurol 58(5):730-735. doi: 10.1002/ana.20629
-
(2005)
Ann Neurol
, vol.58
, Issue.5
, pp. 730-735
-
-
Markesbery, W.R.1
Kryscio, R.J.2
Lovell, M.A.3
Morrow, J.D.4
-
276
-
-
77449103679
-
Inability of plasma and urine F2A-isoprostane levels to differentiate
-
10.1159/000289224 20197693 1:CAS:528:DC%2BC3cXks1KjtLw%3D 10.1159/000289224
-
Mufson EJ, Leurgans S (2010) Inability of plasma and urine F2A-isoprostane levels to differentiate mild cognitive impairment from Alzheimer's disease. Neurodegener Dis 7(1-3):139-142. doi: 10.1159/000289224
-
(2010)
Neurodegener Dis
, vol.7
, Issue.1-3
, pp. 139-142
-
-
Mufson, E.J.1
Leurgans, S.2
-
277
-
-
79952113682
-
Carbonyl proteins as a clinical marker in Alzheimer's disease and its relation to tryptophan degradation and immune activation
-
21086789 1:CAS:528:DC%2BC3cXhsFOnsbzM
-
Greilberger J, Fuchs D, Leblhuber F, Greilberger M, Wintersteiger R, Tafeit E (2010) Carbonyl proteins as a clinical marker in Alzheimer's disease and its relation to tryptophan degradation and immune activation. Clin Lab 56(9-10):441-448
-
(2010)
Clin Lab
, vol.56
, Issue.9-10
, pp. 441-448
-
-
Greilberger, J.1
Fuchs, D.2
Leblhuber, F.3
Greilberger, M.4
Wintersteiger, R.5
Tafeit, E.6
-
278
-
-
77449115593
-
Endurance exercise causes mitochondrial and oxidative stress in rat liver: Effects of a combination of mitochondrial targeting nutrients
-
10.1016/j.lfs.2009.11.003 19913560 1:CAS:528:DC%2BD1MXhs1WgtLbM 10.1016/j.lfs.2009.11.003
-
Sun L, Shen W, Liu Z, Guan S, Liu J, Ding S (2010) Endurance exercise causes mitochondrial and oxidative stress in rat liver: effects of a combination of mitochondrial targeting nutrients. Life Sci 86(1-2):39-44. doi: 10.1016/j.lfs.2009.11.003
-
(2010)
Life Sci
, vol.86
, Issue.1-2
, pp. 39-44
-
-
Sun, L.1
Shen, W.2
Liu, Z.3
Guan, S.4
Liu, J.5
Ding, S.6
-
279
-
-
77952672909
-
Increased levels of 4-hydroxynonenal and acrolein in the brain in preclinical Alzheimer disease
-
10.1016/j.freeradbiomed.2010.02.016 20171275 1:CAS:528: DC%2BC3cXlvVeitrg%3D 10.1016/j.freeradbiomed.2010.02.016
-
Bradley MA, Markesbery WR, Lovell MA (2010) Increased levels of 4-hydroxynonenal and acrolein in the brain in preclinical Alzheimer disease. Free Radic Biol Med 48(12):1570-1576. doi: 10.1016/j.freeradbiomed.2010.02.016
-
(2010)
Free Radic Biol Med
, vol.48
, Issue.12
, pp. 1570-1576
-
-
Bradley, M.A.1
Markesbery, W.R.2
Lovell, M.A.3
-
280
-
-
77953659232
-
Potential role of acrolein in neurodegeneration and in Alzheimer's disease
-
20302565
-
Dang TN, Arseneault M, Murthy V, Ramassamy C (2010) Potential role of acrolein in neurodegeneration and in Alzheimer's disease. Curr Mol Pharmacol 3(2):66-78
-
(2010)
Curr Mol Pharmacol
, vol.3
, Issue.2
, pp. 66-78
-
-
Dang, T.N.1
Arseneault, M.2
Murthy, V.3
Ramassamy, C.4
-
281
-
-
77957256030
-
Role of by-products of lipid oxidation in Alzheimer's disease brain: A focus on acrolein
-
10.3233/JAD-2010-100405 20634576 1:CAS:528:DC%2BC3cXhtFKmurnO
-
Singh M, Dang TN, Arseneault M, Ramassamy C (2010) Role of by-products of lipid oxidation in Alzheimer's disease brain: a focus on acrolein. J Alzheimers Dis 21(3):741-756. doi: 10.3233/JAD-2010-100405
-
(2010)
J Alzheimers Dis
, vol.21
, Issue.3
, pp. 741-756
-
-
Singh, M.1
Dang, T.N.2
Arseneault, M.3
Ramassamy, C.4
-
282
-
-
0142105855
-
Covalent binding of hydroxy-alkenals 4-HDDE, 4-HHE, and 4-HNE to ethanolamine phospholipid subclasses
-
10.1194/jlr.M200450-JLR200 12588949 1:CAS:528:DC%2BD3sXktlSqtLc%3D 10.1194/jlr.M200450-JLR200
-
Bacot S, Bernoud-Hubac N, Baddas N, Chantegrel B, Deshayes C, Doutheau A, Lagarde M, Guichardant M (2003) Covalent binding of hydroxy-alkenals 4-HDDE, 4-HHE, and 4-HNE to ethanolamine phospholipid subclasses. J Lipid Res 44(5):917-926. doi: 10.1194/jlr.M200450-JLR200
-
(2003)
J Lipid Res
, vol.44
, Issue.5
, pp. 917-926
-
-
Bacot, S.1
Bernoud-Hubac, N.2
Baddas, N.3
Chantegrel, B.4
Deshayes, C.5
Doutheau, A.6
Lagarde, M.7
Guichardant, M.8
-
283
-
-
77953257870
-
Involvements of the lipid peroxidation product, HNE, in the pathogenesis and progression of Alzheimer's disease
-
10.1016/j.bbalip.2010.02.005 20176130 1:CAS:528:DC%2BC3cXntlagsL4%3D 10.1016/j.bbalip.2010.02.005
-
Butterfield DA, Bader Lange ML, Sultana R (2010) Involvements of the lipid peroxidation product, HNE, in the pathogenesis and progression of Alzheimer's disease. Biochim Biophys Acta 1801(8):924-929. doi: 10.1016/j.bbalip.2010.02.005
-
(2010)
Biochim Biophys Acta
, vol.1801
, Issue.8
, pp. 924-929
-
-
Butterfield, D.A.1
Bader Lange, M.L.2
Sultana, R.3
-
284
-
-
33846949357
-
The oxidative stress metabolite 4-hydroxynonenal promotes Alzheimer protofibril formation
-
10.1021/bi061853s 17279615 1:CAS:528:DC%2BD2sXmt1ymsw%3D%3D 10.1021/bi061853s
-
Siegel SJ, Bieschke J, Powers ET, Kelly JW (2007) The oxidative stress metabolite 4-hydroxynonenal promotes Alzheimer protofibril formation. Biochemistry 46(6):1503-1510. doi: 10.1021/bi061853s
-
(2007)
Biochemistry
, vol.46
, Issue.6
, pp. 1503-1510
-
-
Siegel, S.J.1
Bieschke, J.2
Powers, E.T.3
Kelly, J.W.4
-
285
-
-
51749088156
-
Redox regulation of cell survival
-
10.1089/ars.2007.1957 18522489 1:CAS:528:DC%2BD1cXms1eqs7g%3D 10.1089/ars.2007.1957
-
Trachootham D, Lu W, Ogasawara MA, Nilsa RD, Huang P (2008) Redox regulation of cell survival. Antioxid Redox Signal 10(8):1343-1374. doi: 10.1089/ars.2007.1957
-
(2008)
Antioxid Redox Signal
, vol.10
, Issue.8
, pp. 1343-1374
-
-
Trachootham, D.1
Lu, W.2
Ogasawara, M.A.3
Nilsa, R.D.4
Huang, P.5
-
286
-
-
0031831270
-
Reactive oxygen-mediated protein oxidation in aging and disease
-
10.3109/03602539808996310 9606602 1:CAS:528:DyaK1cXjsF2qsLw%3D 10.3109/03602539808996310
-
Stadtman ER, Berlett BS (1998) Reactive oxygen-mediated protein oxidation in aging and disease. Drug Metab Rev 30(2):225-243. doi: 10.3109/ 03602539808996310
-
(1998)
Drug Metab Rev
, vol.30
, Issue.2
, pp. 225-243
-
-
Stadtman, E.R.1
Berlett, B.S.2
-
287
-
-
33750720268
-
Protein oxidation and degradation during aging: Role in skin aging and neurodegeneration
-
10.1080/10715760600911154 17090415 1:CAS:528:DC%2BD28XhtlGqs7nM 10.1080/10715760600911154
-
Widmer R, Ziaja I, Grune T (2006) Protein oxidation and degradation during aging: role in skin aging and neurodegeneration. Free Radic Res 40(12):1259-1268. doi: 10.1080/10715760600911154
-
(2006)
Free Radic Res
, vol.40
, Issue.12
, pp. 1259-1268
-
-
Widmer, R.1
Ziaja, I.2
Grune, T.3
-
288
-
-
0344196903
-
NO-dependent protein nitration: A cell signaling event or an oxidative inflammatory response?
-
10.1016/j.tibs.2003.10.006 14659696 1:CAS:528:DC%2BD3sXpsVSksr4%3D 10.1016/j.tibs.2003.10.006
-
Schopfer FJ, Baker PR, Freeman BA (2003) NO-dependent protein nitration: a cell signaling event or an oxidative inflammatory response? Trends Biochem Sci 28(12):646-654. doi: 10.1016/j.tibs.2003.10.006
-
(2003)
Trends Biochem Sci
, vol.28
, Issue.12
, pp. 646-654
-
-
Schopfer, F.J.1
Baker, P.R.2
Freeman, B.A.3
-
289
-
-
33645089917
-
Identification of nitrated proteins in Alzheimer's disease brain using a redox proteomics approach
-
10.1016/j.nbd.2005.10.004 16378731 1:CAS:528:DC%2BD28XivVOjtbo%3D 10.1016/j.nbd.2005.10.004
-
Sultana R, Poon HF, Cai J, Pierce WM, Merchant M, Klein JB, Markesbery WR, Butterfield DA (2006) Identification of nitrated proteins in Alzheimer's disease brain using a redox proteomics approach. Neurobiol Dis 22(1):76-87. doi: 10.1016/j.nbd.2005.10.004
-
(2006)
Neurobiol Dis
, vol.22
, Issue.1
, pp. 76-87
-
-
Sultana, R.1
Poon, H.F.2
Cai, J.3
Pierce, W.M.4
Merchant, M.5
Klein, J.B.6
Markesbery, W.R.7
Butterfield, D.A.8
-
290
-
-
34547666858
-
S-glutathionylation in protein redox regulation
-
10.1016/j.freeradbiomed.2007.06.014 17697933 1:CAS:528: DC%2BD2sXovFOqtbc%3D 10.1016/j.freeradbiomed.2007.06.014
-
Dalle-Donne I, Rossi R, Giustarini D, Colombo R, Milzani A (2007) S-glutathionylation in protein redox regulation. Free Radic Biol Med 43(6):883-898. doi: 10.1016/j.freeradbiomed.2007.06.014
-
(2007)
Free Radic Biol Med
, vol.43
, Issue.6
, pp. 883-898
-
-
Dalle-Donne, I.1
Rossi, R.2
Giustarini, D.3
Colombo, R.4
Milzani, A.5
-
291
-
-
14044272119
-
S-Glutathionylation: From redox regulation of protein functions to human diseases
-
15256068 1:CAS:528:DC%2BD2MXlt1KqtL8%3D 10.1111/j.1582-4934.2004.tb00275. x
-
Giustarini D, Rossi R, Milzani A, Colombo R, Dalle-Donne I (2004) S-Glutathionylation: from redox regulation of protein functions to human diseases. J Cell Mol Med 8(2):201-212
-
(2004)
J Cell Mol Med
, vol.8
, Issue.2
, pp. 201-212
-
-
Giustarini, D.1
Rossi, R.2
Milzani, A.3
Colombo, R.4
Dalle-Donne, I.5
-
292
-
-
84860446262
-
Age- and gender-related alteration in plasma advanced oxidation protein products (AOPP) and glycosaminoglycan (GAG) concentrations in physiological ageing
-
doi: 10.1515/CCLM.2011.789
-
Komosinska-Vassev K, Olczyk P, Winsz-Szczotka K, Kuznik-Trocha K, Klimek K, Olczyk K (2011) Age- and gender-related alteration in plasma advanced oxidation protein products (AOPP) and glycosaminoglycan (GAG) concentrations in physiological ageing. Clin Chem Lab Med, doi: 10.1515/CCLM.2011.789
-
(2011)
Clin Chem Lab Med
-
-
Komosinska-Vassev, K.1
Olczyk, P.2
Winsz-Szczotka, K.3
Kuznik-Trocha, K.4
Klimek, K.5
Olczyk, K.6
-
293
-
-
80053006895
-
Cell signaling and receptors in toxicity of advanced glycation end products (AGEs): Alpha-dicarbonyls, radicals, oxidative stress and antioxidants
-
10.3109/10799893.2011.607171 21929288 1:CAS:528:DC%2BC3MXhtFyqsb3J 10.3109/10799893.2011.607171
-
Kovacic P, Somanathan R (2011) Cell signaling and receptors in toxicity of advanced glycation end products (AGEs): alpha-dicarbonyls, radicals, oxidative stress and antioxidants. J Recept Signal Transduct Res 31(5):332-339. doi: 10.3109/10799893.2011.607171
-
(2011)
J Recept Signal Transduct Res
, vol.31
, Issue.5
, pp. 332-339
-
-
Kovacic, P.1
Somanathan, R.2
-
294
-
-
0036972669
-
Advanced glycation end-products and advanced oxidation protein products in patients with diabetes mellitus
-
1:CAS:528:DC%2BD3sXhs1yrtLo%3D
-
Kalousova M, Skrha J, Zima T (2002) Advanced glycation end-products and advanced oxidation protein products in patients with diabetes mellitus. Physiol Res Acad Sci Bohemoslovaca 51(6):597-604
-
(2002)
Physiol Res Acad Sci Bohemoslovaca
, vol.51
, Issue.6
, pp. 597-604
-
-
Kalousova, M.1
Skrha, J.2
Zima, T.3
-
295
-
-
74249094452
-
Increased low-density lipoprotein oxidation, but not total plasma protein oxidation, in Alzheimer's disease
-
10.1016/j.clinbiochem.2009.08.021 19733555 1:CAS:528: DC%2BC3cXpslSrsA%3D%3D 10.1016/j.clinbiochem.2009.08.021
-
Aldred S, Bennett S, Mecocci P (2010) Increased low-density lipoprotein oxidation, but not total plasma protein oxidation, in Alzheimer's disease. Clin Biochem 43(3):267-271. doi: 10.1016/j.clinbiochem.2009.08.021
-
(2010)
Clin Biochem
, vol.43
, Issue.3
, pp. 267-271
-
-
Aldred, S.1
Bennett, S.2
Mecocci, P.3
-
296
-
-
67650128942
-
Paraoxonase activity and dementia
-
10.1016/j.jns.2009.02.317 19268306 1:CAS:528:DC%2BD1MXoslSisb8%3D 10.1016/j.jns.2009.02.317
-
Wehr H, Bednarska-Makaruk M, Graban A, Lipczynska-Lojkowska W, Rodo M, Bochynska A, Ryglewicz D (2009) Paraoxonase activity and dementia. J Neurol Sci 283(1-2):107-108. doi: 10.1016/j.jns.2009.02.317
-
(2009)
J Neurol Sci
, vol.283
, Issue.1-2
, pp. 107-108
-
-
Wehr, H.1
Bednarska-Makaruk, M.2
Graban, A.3
Lipczynska-Lojkowska, W.4
Rodo, M.5
Bochynska, A.6
Ryglewicz, D.7
-
297
-
-
34347383021
-
Nitric oxide and nitroxidative stress in Alzheimer's disease
-
17522445 1:CAS:528:DC%2BD2sXlsVCitb8%3D
-
Malinski T (2007) Nitric oxide and nitroxidative stress in Alzheimer's disease. J Alzheimers Dis 11(2):207-218
-
(2007)
J Alzheimers Dis
, vol.11
, Issue.2
, pp. 207-218
-
-
Malinski, T.1
-
298
-
-
41149166082
-
Nucleic acid oxidation in Alzheimer disease
-
10.1016/j.freeradbiomed.2008.01.002 18258207 1:CAS:528: DC%2BD1cXktlGls7w%3D 10.1016/j.freeradbiomed.2008.01.002
-
Moreira PI, Nunomura A, Nakamura M, Takeda A, Shenk JC, Aliev G, Smith MA, Perry G (2008) Nucleic acid oxidation in Alzheimer disease. Free Radic Biol Med 44(8):1493-1505. doi: 10.1016/j.freeradbiomed.2008.01.002
-
(2008)
Free Radic Biol Med
, vol.44
, Issue.8
, pp. 1493-1505
-
-
Moreira, P.I.1
Nunomura, A.2
Nakamura, M.3
Takeda, A.4
Shenk, J.C.5
Aliev, G.6
Smith, M.A.7
Perry, G.8
-
299
-
-
33645106680
-
Increased oxidative damage in nuclear and mitochondrial DNA in mild cognitive impairment
-
10.1111/j.1471-4159.2005.03615.x 16405502 1:CAS:528:DC%2BD28XjsFCnu7g%3D 10.1111/j.1471-4159.2005.03615.x
-
Wang J, Markesbery WR, Lovell MA (2006) Increased oxidative damage in nuclear and mitochondrial DNA in mild cognitive impairment. J Neurochem 96(3):825-832. doi: 10.1111/j.1471-4159.2005.03615.x
-
(2006)
J Neurochem
, vol.96
, Issue.3
, pp. 825-832
-
-
Wang, J.1
Markesbery, W.R.2
Lovell, M.A.3
-
300
-
-
38149087424
-
Oxidatively modified RNA in mild cognitive impairment
-
10.1016/j.nbd.2007.07.030 17920285 1:CAS:528:DC%2BD1cXptlSgsQ%3D%3D 10.1016/j.nbd.2007.07.030
-
Lovell MA, Markesbery WR (2008) Oxidatively modified RNA in mild cognitive impairment. Neurobiol Dis 29(2):169-175. doi: 10.1016/j.nbd.2007.07. 030
-
(2008)
Neurobiol Dis
, vol.29
, Issue.2
, pp. 169-175
-
-
Lovell, M.A.1
Markesbery, W.R.2
-
301
-
-
0036141861
-
Elevated levels of oxidative DNA damage in lymphocytes from patients with Alzheimer's disease
-
11755018 1:CAS:528:DC%2BD3MXptFyltb0%3D 10.1016/S0197-4580(01)00257-3
-
Morocz M, Kalman J, Juhasz A, Sinko I, McGlynn AP, Downes CS, Janka Z, Rasko I (2002) Elevated levels of oxidative DNA damage in lymphocytes from patients with Alzheimer's disease. Neurobiol Aging 23(1):47-53
-
(2002)
Neurobiol Aging
, vol.23
, Issue.1
, pp. 47-53
-
-
Morocz, M.1
Kalman, J.2
Juhasz, A.3
Sinko, I.4
McGlynn, A.P.5
Downes, C.S.6
Janka, Z.7
Rasko, I.8
-
302
-
-
38049010515
-
Oxidative DNA damage in mild cognitive impairment and late-stage Alzheimer's disease
-
10.1093/nar/gkm821 17947327 1:CAS:528:DC%2BD1cXisF2isg%3D%3D 10.1093/nar/gkm821
-
Lovell MA, Markesbery WR (2007) Oxidative DNA damage in mild cognitive impairment and late-stage Alzheimer's disease. Nucleic Acids Res 35(22):7497-7504. doi: 10.1093/nar/gkm821
-
(2007)
Nucleic Acids Res
, vol.35
, Issue.22
, pp. 7497-7504
-
-
Lovell, M.A.1
Markesbery, W.R.2
-
303
-
-
67349251839
-
RNA oxidation in Alzheimer disease and related neurodegenerative disorders
-
10.1007/s00401-009-0508-1 19271225 1:CAS:528:DC%2BD1MXmt1agsr4%3D 10.1007/s00401-009-0508-1
-
Nunomura A, Hofer T, Moreira PI, Castellani RJ, Smith MA, Perry G (2009) RNA oxidation in Alzheimer disease and related neurodegenerative disorders. Acta Neuropathol 118(1):151-166. doi: 10.1007/s00401-009-0508-1
-
(2009)
Acta Neuropathol
, vol.118
, Issue.1
, pp. 151-166
-
-
Nunomura, A.1
Hofer, T.2
Moreira, P.I.3
Castellani, R.J.4
Smith, M.A.5
Perry, G.6
-
304
-
-
84861188552
-
Non-coding RNAs - Novel targets in neurotoxicity
-
10.1016/j.neuro.2012.02.013 22394481 1:CAS:528:DC%2BC38XntlOhsbg%3D 10.1016/j.neuro.2012.02.013
-
Tal TL, Tanguay RL (2012) Non-coding RNAs - novel targets in neurotoxicity. Neurotoxicology 33(3):530-544. doi: 10.1016/j.neuro.2012.02.013
-
(2012)
Neurotoxicology
, vol.33
, Issue.3
, pp. 530-544
-
-
Tal, T.L.1
Tanguay, R.L.2
-
305
-
-
79952998056
-
Antioxidants in the treatment of diabetes
-
21294707 1:CAS:528:DC%2BC3MXmsVeitbs%3D 10.2174/157339911794940729
-
Golbidi S, Ebadi SA, Laher I (2011) Antioxidants in the treatment of diabetes. Curr Diabetes Rev 7(2):106-125
-
(2011)
Curr Diabetes Rev
, vol.7
, Issue.2
, pp. 106-125
-
-
Golbidi, S.1
Ebadi, S.A.2
Laher, I.3
-
306
-
-
26844564082
-
Oxidative stress and the use of antioxidants in diabetes: Linking basic science to clinical practice
-
10.1186/1475-2840-4-5 15862133 10.1186/1475-2840-4-5 1:CAS:528: DC%2BD28XjsFSnsw%3D%3D
-
Johansen JS, Harris AK, Rychly DJ, Ergul A (2005) Oxidative stress and the use of antioxidants in diabetes: linking basic science to clinical practice. Cardiovasc Diabetol 4(1):5. doi: 10.1186/1475-2840-4-5
-
(2005)
Cardiovasc Diabetol
, vol.4
, Issue.1
, pp. 5
-
-
Johansen, J.S.1
Harris, A.K.2
Rychly, D.J.3
Ergul, A.4
-
307
-
-
83455186444
-
Antioxidant pathways in Alzheimer's disease: Possibilities of intervention
-
21933145 1:CAS:528:DC%2BC38XovV2jsg%3D%3D 10.2174/138161211798357755
-
Vina J, Lloret A, Giraldo E, Badia MC, Alonso MD (2011) Antioxidant pathways in Alzheimer's disease: possibilities of intervention. Curr Pharm Des 17(35):3861-3864
-
(2011)
Curr Pharm des
, vol.17
, Issue.35
, pp. 3861-3864
-
-
Vina, J.1
Lloret, A.2
Giraldo, E.3
Badia, M.C.4
Alonso, M.D.5
-
308
-
-
79960626655
-
Early calcium dysregulation in Alzheimer's disease: Setting the stage for synaptic dysfunction
-
10.1007/s11427-011-4205-7 21786198 1:CAS:528:DC%2BC3MXptlyjtb0%3D 10.1007/s11427-011-4205-7
-
Chakroborty S, Stutzmann GE (2011) Early calcium dysregulation in Alzheimer's disease: setting the stage for synaptic dysfunction. Sci China Life Sci 54(8):752-762. doi: 10.1007/s11427-011-4205-7
-
(2011)
Sci China Life Sci
, vol.54
, Issue.8
, pp. 752-762
-
-
Chakroborty, S.1
Stutzmann, G.E.2
-
309
-
-
64349083615
-
Transglutaminases and neurodegeneration
-
10.1111/j.1471-4159.2009.05843.x 19393023 1:CAS:528:DC%2BD1MXlsFyksbY%3D 10.1111/j.1471-4159.2009.05843.x
-
Jeitner TM, Pinto JT, Krasnikov BF, Horswill M, Cooper AJ (2009) Transglutaminases and neurodegeneration. J Neurochem 109(Suppl 1):160-166. doi: 10.1111/j.1471-4159.2009.05843.x
-
(2009)
J Neurochem
, vol.109
, Issue.SUPPL. 1
, pp. 160-166
-
-
Jeitner, T.M.1
Pinto, J.T.2
Krasnikov, B.F.3
Horswill, M.4
Cooper, A.J.5
-
310
-
-
84862908515
-
Effects of amyloid-beta peptides on voltage-gated L-type Ca(V)1.2 and Ca(V)1.3 Ca(2+) channels
-
10.1007/s10059-011-0075-x 21822937 1:CAS:528:DC%2BC3MXht1ClurvF 10.1007/s10059-011-0075-x
-
Kim S, Rhim H (2011) Effects of amyloid-beta peptides on voltage-gated L-type Ca(V)1.2 and Ca(V)1.3 Ca(2+) channels. Mol Cells 32(3):289-294. doi: 10.1007/s10059-011-0075-x
-
(2011)
Mol Cells
, vol.32
, Issue.3
, pp. 289-294
-
-
Kim, S.1
Rhim, H.2
-
311
-
-
44949196953
-
Impact of mitochondrial calcium on the coupling of metabolism to insulin secretion in the pancreatic beta-cell
-
10.1016/j.ceca.2007.11.004 18191448 1:CAS:528:DC%2BD1cXntlaiur0%3D 10.1016/j.ceca.2007.11.004
-
Wiederkehr A, Wollheim CB (2008) Impact of mitochondrial calcium on the coupling of metabolism to insulin secretion in the pancreatic beta-cell. Cell Calcium 44(1):64-76. doi: 10.1016/j.ceca.2007.11.004
-
(2008)
Cell Calcium
, vol.44
, Issue.1
, pp. 64-76
-
-
Wiederkehr, A.1
Wollheim, C.B.2
-
312
-
-
77549084735
-
Abnormal calcium homeostasis in peripheral neuropathies
-
10.1016/j.ceca.2009.11.008 20034667 1:CAS:528:DC%2BC3cXjtVSmsro%3D 10.1016/j.ceca.2009.11.008
-
Fernyhough P, Calcutt NA (2010) Abnormal calcium homeostasis in peripheral neuropathies. Cell Calcium 47(2):130-139. doi: 10.1016/j.ceca.2009. 11.008
-
(2010)
Cell Calcium
, vol.47
, Issue.2
, pp. 130-139
-
-
Fernyhough, P.1
Calcutt, N.A.2
-
313
-
-
44749091551
-
2+ dyshomeostasis drive neuronal pathology in diabetes
-
10.1016/j.ceca.2007.11.010 18191198 1:CAS:528:DC%2BD1cXntlaitLY%3D 10.1016/j.ceca.2007.11.010
-
2+ dyshomeostasis drive neuronal pathology in diabetes. Cell Calcium 44(1):112-122. doi: 10.1016/j.ceca.2007.11.010
-
(2008)
Cell Calcium
, vol.44
, Issue.1
, pp. 112-122
-
-
Verkhratsky, A.1
Fernyhough, P.2
-
314
-
-
33847698158
-
Rosiglitazone induces mitochondrial biogenesis in mouse brain
-
17361034 1:CAS:528:DC%2BD2sXisVGju70%3D
-
Strum JC, Shehee R, Virley D, Richardson J, Mattie M, Selley P, Ghosh S, Nock C, Saunders A, Roses A (2007) Rosiglitazone induces mitochondrial biogenesis in mouse brain. J Alzheimers Dis 11(1):45-51
-
(2007)
J Alzheimers Dis
, vol.11
, Issue.1
, pp. 45-51
-
-
Strum, J.C.1
Shehee, R.2
Virley, D.3
Richardson, J.4
Mattie, M.5
Selley, P.6
Ghosh, S.7
Nock, C.8
Saunders, A.9
Roses, A.10
-
315
-
-
79959479102
-
Efficacy of PPAR-gamma agonist pioglitazone in mild Alzheimer disease
-
10.1016/j.neurobiolaging.2009.10.009 19923038 1:CAS:528: DC%2BC3MXovFOmu7s%3D 10.1016/j.neurobiolaging.2009.10.009
-
Sato T, Hanyu H, Hirao K, Kanetaka H, Sakurai H, Iwamoto T (2011) Efficacy of PPAR-gamma agonist pioglitazone in mild Alzheimer disease. Neurobiol Aging 32(9):1626-1633. doi: 10.1016/j.neurobiolaging.2009.10.009
-
(2011)
Neurobiol Aging
, vol.32
, Issue.9
, pp. 1626-1633
-
-
Sato, T.1
Hanyu, H.2
Hirao, K.3
Kanetaka, H.4
Sakurai, H.5
Iwamoto, T.6
-
316
-
-
45949088803
-
Insulin-like growth factor system regulates oligodendroglial cell behavior: Therapeutic potential in CNS
-
10.1007/s12031-008-9041-2 18299999 1:CAS:528:DC%2BD1cXmtlamtrg%3D 10.1007/s12031-008-9041-2
-
Chesik D, De Keyser J, Wilczak N (2008) Insulin-like growth factor system regulates oligodendroglial cell behavior: therapeutic potential in CNS. J Mol Neurosci 35(1):81-90. doi: 10.1007/s12031-008-9041-2
-
(2008)
J Mol Neurosci
, vol.35
, Issue.1
, pp. 81-90
-
-
Chesik, D.1
De Keyser, J.2
Wilczak, N.3
-
317
-
-
84855435177
-
Ginsenoside Rg1 attenuates beta-amyloid generation via suppressing PPARgamma-regulated BACE1 activity in N2a-APP695 cells
-
10.1016/j.ejphar.2011.11.039 22166376 1:CAS:528:DC%2BC38Xkslajug%3D%3D 10.1016/j.ejphar.2011.11.039
-
Chen LM, Lin ZY, Zhu YG, Lin N, Zhang J, Pan XD, Chen XC (2012) Ginsenoside Rg1 attenuates beta-amyloid generation via suppressing PPARgamma-regulated BACE1 activity in N2a-APP695 cells. Eur J Pharmacol 675(1-3):15-21. doi: 10.1016/j.ejphar.2011.11.039
-
(2012)
Eur J Pharmacol
, vol.675
, Issue.1-3
, pp. 15-21
-
-
Chen, L.M.1
Lin, Z.Y.2
Zhu, Y.G.3
Lin, N.4
Zhang, J.5
Pan, X.D.6
Chen, X.C.7
-
318
-
-
79957946047
-
Neurovascular function in Alzheimer's disease patients and experimental models
-
10.1038/jcbfm.2011.43 1:CAS:528:DC%2BC3MXmvFyjtLk%3D 10.1038/jcbfm.2011. 43
-
Nicolakakis N, Hamel E (2011) Neurovascular function in Alzheimer's disease patients and experimental models. J Cereb Blood Flow Metab Off J Int Soc Cereb Blood Flow Metab 31(6):1354-1370. doi: 10.1038/jcbfm.2011.43
-
(2011)
J Cereb Blood Flow Metab off J Int Soc Cereb Blood Flow Metab
, vol.31
, Issue.6
, pp. 1354-1370
-
-
Nicolakakis, N.1
Hamel, E.2
-
319
-
-
79961166873
-
Neuroprotective mechanisms of peroxisome proliferator-activated receptor agonists in Alzheimer's disease
-
10.1007/s00210-011-0654-6 1:CAS:528:DC%2BC3MXpsFOktr4%3D 10.1007/s00210-011-0654-6
-
Sodhi RK, Singh N, Jaggi AS (2011) Neuroprotective mechanisms of peroxisome proliferator-activated receptor agonists in Alzheimer's disease. Naunyn Schmiedeberg's Arch Pharmacol 384(2):115-124. doi: 10.1007/s00210-011- 0654-6
-
(2011)
Naunyn Schmiedeberg's Arch Pharmacol
, vol.384
, Issue.2
, pp. 115-124
-
-
Sodhi, R.K.1
Singh, N.2
Jaggi, A.S.3
-
320
-
-
58149265311
-
Pioglitazone improved cognition in a pilot study on patients with Alzheimer's disease and mild cognitive impairment with diabetes mellitus
-
10.1111/j.1532-5415.2009.02067.x 19170800 10.1111/j.1532-5415.2009.02067. x
-
Hanyu H, Sato T, Kiuchi A, Sakurai H, Iwamoto T (2009) Pioglitazone improved cognition in a pilot study on patients with Alzheimer's disease and mild cognitive impairment with diabetes mellitus. J Am Geriatr Soc 57(1):177-179. doi: 10.1111/j.1532-5415.2009.02067.x
-
(2009)
J Am Geriatr Soc
, vol.57
, Issue.1
, pp. 177-179
-
-
Hanyu, H.1
Sato, T.2
Kiuchi, A.3
Sakurai, H.4
Iwamoto, T.5
-
321
-
-
84862946286
-
Diabetes-induced central cholinergic neuronal loss and cognitive deficit are attenuated by tacrine and a Chinese herbal prescription, kangen-karyu: Elucidation in type 2 diabetes db/db mice
-
22083044 1:CAS:528:DC%2BC38Xjt1Cgug%3D%3D 10.1254/jphs.11115FP
-
Zhao Q, Matsumoto K, Tsuneyama K, Tanaka K, Li F, Shibahara N, Miyata T, Yokozawa T (2011) Diabetes-induced central cholinergic neuronal loss and cognitive deficit are attenuated by tacrine and a Chinese herbal prescription, kangen-karyu: elucidation in type 2 diabetes db/db mice. J Pharmacol Sci 117(4):230-242
-
(2011)
J Pharmacol Sci
, vol.117
, Issue.4
, pp. 230-242
-
-
Zhao, Q.1
Matsumoto, K.2
Tsuneyama, K.3
Tanaka, K.4
Li, F.5
Shibahara, N.6
Miyata, T.7
Yokozawa, T.8
-
322
-
-
84862777666
-
ApoE-directed therapeutics rapidly clear beta-amyloid and reverse deficits in AD mouse models
-
10.1126/science.1217697 22323736 1:CAS:528:DC%2BC38XktFWksbY%3D 10.1126/science.1217697
-
Cramer PE, Cirrito JR, Wesson DW, Lee CY, Karlo JC, Zinn AE, Casali BT, Restivo JL, Goebel WD, James MJ, Brunden KR, Wilson DA, Landreth GE (2012) ApoE-directed therapeutics rapidly clear beta-amyloid and reverse deficits in AD mouse models. Science 335(6075):1503-1506. doi: 10.1126/science.1217697
-
(2012)
Science
, vol.335
, Issue.6075
, pp. 1503-1506
-
-
Cramer, P.E.1
Cirrito, J.R.2
Wesson, D.W.3
Lee, C.Y.4
Karlo, J.C.5
Zinn, A.E.6
Casali, B.T.7
Restivo, J.L.8
Goebel, W.D.9
James, M.J.10
Brunden, K.R.11
Wilson, D.A.12
Landreth, G.E.13
-
323
-
-
17744376173
-
A PPAR gamma-LXR-ABCA1 pathway in macrophages is involved in cholesterol efflux and atherogenesis
-
11172721 1:CAS:528:DC%2BD3MXis1KisbY%3D 10.1016/S1097-2765(01)00164-2
-
Chawla A, Boisvert WA, Lee CH, Laffitte BA, Barak Y, Joseph SB, Liao D, Nagy L, Edwards PA, Curtiss LK, Evans RM, Tontonoz P (2001) A PPAR gamma-LXR-ABCA1 pathway in macrophages is involved in cholesterol efflux and atherogenesis. Mol Cell 7(1):161-171
-
(2001)
Mol Cell
, vol.7
, Issue.1
, pp. 161-171
-
-
Chawla, A.1
Boisvert, W.A.2
Lee, C.H.3
Laffitte, B.A.4
Barak, Y.5
Joseph, S.B.6
Liao, D.7
Nagy, L.8
Edwards, P.A.9
Curtiss, L.K.10
Evans, R.M.11
Tontonoz, P.12
-
324
-
-
78049278719
-
Retinoid X receptors: Common heterodimerization partners with distinct functions
-
10.1016/j.tem.2010.06.009 20674387 1:CAS:528:DC%2BC3cXhtlKltL%2FN 10.1016/j.tem.2010.06.009
-
Lefebvre P, Benomar Y, Staels B (2010) Retinoid X receptors: common heterodimerization partners with distinct functions. Trends Endocrinol Metab 21(11):676-683. doi: 10.1016/j.tem.2010.06.009
-
(2010)
Trends Endocrinol Metab
, vol.21
, Issue.11
, pp. 676-683
-
-
Lefebvre, P.1
Benomar, Y.2
Staels, B.3
-
325
-
-
32644460092
-
From molecular action to physiological outputs: Peroxisome proliferator-activated receptors are nuclear receptors at the crossroads of key cellular functions
-
10.1016/j.plipres.2005.12.002 16476485 1:CAS:528:DC%2BD28Xhslyjsrg%3D 10.1016/j.plipres.2005.12.002
-
Feige JN, Gelman L, Michalik L, Desvergne B, Wahli W (2006) From molecular action to physiological outputs: peroxisome proliferator-activated receptors are nuclear receptors at the crossroads of key cellular functions. Prog Lipid Res 45(2):120-159. doi: 10.1016/j.plipres.2005.12.002
-
(2006)
Prog Lipid Res
, vol.45
, Issue.2
, pp. 120-159
-
-
Feige, J.N.1
Gelman, L.2
Michalik, L.3
Desvergne, B.4
Wahli, W.5
-
326
-
-
62649115914
-
Antidiabetic drug metformin (GlucophageR) increases biogenesis of Alzheimer's amyloid peptides via up-regulating BACE1 transcription
-
10.1073/pnas.0807991106 19237574 1:CAS:528:DC%2BD1MXjt1Gktr4%3D 10.1073/pnas.0807991106
-
Chen Y, Zhou K, Wang R, Liu Y, Kwak YD, Ma T, Thompson RC, Zhao Y, Smith L, Gasparini L, Luo Z, Xu H, Liao FF (2009) Antidiabetic drug metformin (GlucophageR) increases biogenesis of Alzheimer's amyloid peptides via up-regulating BACE1 transcription. Proc Natl Acad Sci U S A 106(10):3907-3912. doi: 10.1073/pnas.0807991106
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, Issue.10
, pp. 3907-3912
-
-
Chen, Y.1
Zhou, K.2
Wang, R.3
Liu, Y.4
Kwak, Y.D.5
Ma, T.6
Thompson, R.C.7
Zhao, Y.8
Smith, L.9
Gasparini, L.10
Luo, Z.11
Xu, H.12
Liao, F.F.13
-
327
-
-
78650746798
-
Biguanide metformin acts on tau phosphorylation via mTOR/protein phosphatase 2A (PP2A) signaling
-
10.1073/pnas.0912793107 21098287 1:CAS:528:DC%2BC3cXhs1SqurfF 10.1073/pnas.0912793107
-
Kickstein E, Krauss S, Thornhill P, Rutschow D, Zeller R, Sharkey J, Williamson R, Fuchs M, Kohler A, Glossmann H, Schneider R, Sutherland C, Schweiger S (2010) Biguanide metformin acts on tau phosphorylation via mTOR/protein phosphatase 2A (PP2A) signaling. Proc Natl Acad Sci U S A 107(50):21830-21835. doi: 10.1073/pnas.0912793107
-
(2010)
Proc Natl Acad Sci U S A
, vol.107
, Issue.50
, pp. 21830-21835
-
-
Kickstein, E.1
Krauss, S.2
Thornhill, P.3
Rutschow, D.4
Zeller, R.5
Sharkey, J.6
Williamson, R.7
Fuchs, M.8
Kohler, A.9
Glossmann, H.10
Schneider, R.11
Sutherland, C.12
Schweiger, S.13
-
328
-
-
79952439187
-
Peripheral insulin-sensitizer drug metformin ameliorates neuronal insulin resistance and Alzheimer's-like changes
-
10.1016/j.neuropharm.2011.01.033 21277873 1:CAS:528:DC%2BC3MXjsFahur0%3D 10.1016/j.neuropharm.2011.01.033
-
Gupta A, Bisht B, Dey CS (2011) Peripheral insulin-sensitizer drug metformin ameliorates neuronal insulin resistance and Alzheimer's-like changes. Neuropharmacology 60(6):910-920. doi: 10.1016/j.neuropharm.2011.01.033
-
(2011)
Neuropharmacology
, vol.60
, Issue.6
, pp. 910-920
-
-
Gupta, A.1
Bisht, B.2
Dey, C.S.3
-
329
-
-
78650117774
-
Modeling human diseases in Caenorhabditis elegans
-
10.1002/biot.201000183 21154667 1:CAS:528:DC%2BC3cXhsFeqt77K 10.1002/biot.201000183
-
Markaki M, Tavernarakis N (2010) Modeling human diseases in Caenorhabditis elegans. Biotechnol J 5(12):1261-1276. doi: 10.1002/biot. 201000183
-
(2010)
Biotechnol J
, vol.5
, Issue.12
, pp. 1261-1276
-
-
Markaki, M.1
Tavernarakis, N.2
-
330
-
-
67649690124
-
The model Caenorhabditis elegans in diabetes mellitus and Alzheimer's disease
-
10.3233/JAD-2009-0977 19387121
-
Morcos M, Hutter H (2009) The model Caenorhabditis elegans in diabetes mellitus and Alzheimer's disease. J Alzheimers Dis 16(4):897-908. doi: 10.3233/JAD-2009-0977
-
(2009)
J Alzheimers Dis
, vol.16
, Issue.4
, pp. 897-908
-
-
Morcos, M.1
Hutter, H.2
-
331
-
-
0036725918
-
Ginkgo biloba extract EGb 761 increases stress resistance and extends life span of Caenorhabditis elegans
-
12396085 1:CAS:528:DC%2BD38XotVGmu70%3D
-
Wu Z, Smith JV, Paramasivam V, Butko P, Khan I, Cypser JR, Luo Y (2002) Ginkgo biloba extract EGb 761 increases stress resistance and extends life span of Caenorhabditis elegans. Cell Mol Biol 48(6):725-731
-
(2002)
Cell Mol Biol
, vol.48
, Issue.6
, pp. 725-731
-
-
Wu, Z.1
Smith, J.V.2
Paramasivam, V.3
Butko, P.4
Khan, I.5
Cypser, J.R.6
Luo, Y.7
-
332
-
-
80055117409
-
Assaying beta-amyloid toxicity using a transgenic C. elegans model
-
doi: 10.3791/2252
-
Dostal V, Link CD (2010) Assaying beta-amyloid toxicity using a transgenic C. elegans model. Journal of visualized experiments: JoVE (44). doi: 10.3791/2252
-
(2010)
Journal of Visualized Experiments: JoVE
, Issue.44
-
-
Dostal, V.1
Link, C.D.2
-
333
-
-
77649311383
-
Metformin induces a dietary restriction-like state and the oxidative stress response to extend C. elegans Healthspan via AMPK, LKB1, and SKN-1
-
10.1371/journal.pone.0008758 20090912 10.1371/journal.pone.0008758 1:CAS:528:DC%2BC3cXpvVersg%3D%3D
-
Onken B, Driscoll M (2010) Metformin induces a dietary restriction-like state and the oxidative stress response to extend C. elegans Healthspan via AMPK, LKB1, and SKN-1. PLoS One 5(1):e8758. doi: 10.1371/journal.pone.0008758
-
(2010)
PLoS One
, vol.5
, Issue.1
, pp. 8758
-
-
Onken, B.1
Driscoll, M.2
-
334
-
-
84856225429
-
Reserpine modulates neurotransmitter release to extend lifespan and alleviate age-dependent Abeta proteotoxicity in Caenorhabditis elegans
-
10.1016/j.exger.2011.12.006 22212533 1:CAS:528:DC%2BC38XhsVGrsrw%3D 10.1016/j.exger.2011.12.006
-
Saharia K, Arya U, Kumar R, Sahu R, Das CK, Gupta K, Dwivedi H, Subramaniam JR (2012) Reserpine modulates neurotransmitter release to extend lifespan and alleviate age-dependent Abeta proteotoxicity in Caenorhabditis elegans. Exp Gerontol 47(2):188-197. doi: 10.1016/j.exger.2011.12.006
-
(2012)
Exp Gerontol
, vol.47
, Issue.2
, pp. 188-197
-
-
Saharia, K.1
Arya, U.2
Kumar, R.3
Sahu, R.4
Das, C.K.5
Gupta, K.6
Dwivedi, H.7
Subramaniam, J.R.8
|