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Volumn 4, Issue , 2005, Pages

Oxidative stress and the use of antioxidants in diabetes: Linking basic science to clinical pratice

Author keywords

Antioxidants; Diabetes; Oxidative Stress

Indexed keywords

2,4 THIAZOLIDINEDIONE DERIVATIVE; ACETYLSALICYLIC ACID; ALPHA TOCOPHEROL; ANGIOTENSIN 2 RECEPTOR ANTAGONIST; ANTIOXIDANT; ASCORBIC ACID; BETA CAROTENE; CHROMIUM PICOLINATE; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; FOLIC ACID; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; PIOGLITAZONE; PLACEBO; PROPIONYLCARNITINE; RAMIPRIL; RETINOL; ROSIGLITAZONE; RUBOXISTAURIN; THIOCTIC ACID; TROGLITAZONE; FREE RADICAL; REACTIVE OXYGEN METABOLITE;

EID: 26844564082     PISSN: 14752840     EISSN: 14752840     Source Type: Journal    
DOI: 10.1186/1475-2840-4-5     Document Type: Review
Times cited : (779)

References (79)
  • 1
    • 0023090431 scopus 로고
    • Diabetes and atherosclerosis: An epidemiologic view
    • Pyorala K, Laakso M, Uusitupa M: Diabetes and atherosclerosis: an epidemiologic view. Diabetes Metab Rev 1987, 3(2):463-524.
    • (1987) Diabetes Metab. Rev. , vol.3 , Issue.2 , pp. 463-524
    • Pyorala, K.1    Laakso, M.2    Uusitupa, M.3
  • 2
    • 0032908858 scopus 로고    scopus 로고
    • Hyperglycemia and cardiovascular disease in type 2 diabetes
    • Laakso M: Hyperglycemia and cardiovascular disease in type 2 diabetes. Diabetes 1999, 48(5):937-942.
    • (1999) Diabetes , vol.48 , Issue.5 , pp. 937-942
    • Laakso, M.1
  • 3
    • 0003717478 scopus 로고    scopus 로고
    • National diabetes fact sheet
    • American Diabetes Association
    • American Diabetes Association: National diabetes fact sheet. 2002 [http://www.diabetes.org/diabetes-statistics.jsp].
    • (2002)
  • 4
    • 0027370108 scopus 로고
    • The effect of intensive treatment of diabetes on the development and progression of long-term complications in insulin-dependent diabetes mellitus
    • The Diabetes Control and Complications Trial Research Group
    • The Diabetes Control and Complications Trial Research Group: The effect of intensive treatment of diabetes on the development and progression of long-term complications in insulin-dependent diabetes mellitus. N Engl J Med 1993, 329(14):977-986.
    • (1993) N. Engl. J. Med. , vol.329 , Issue.14 , pp. 977-986
  • 5
    • 0030048496 scopus 로고    scopus 로고
    • Oxidative stress and diabetic vascular complications
    • Giugliano D, Ceriello A, Paolisso G: Oxidative stress and diabetic vascular complications. Diabetes Care 1996, 19(3):257-267.
    • (1996) Diabetes Care , vol.19 , Issue.3 , pp. 257-267
    • Giugliano, D.1    Ceriello, A.2    Paolisso, G.3
  • 6
    • 0042093769 scopus 로고    scopus 로고
    • New insights on oxidative stress and diabetic complications may lead to a "causal" antioxidant therapy
    • Ceriello A: New insights on oxidative stress and diabetic complications may lead to a "causal" antioxidant therapy. Diabetes Care 2003, 26(5):1589-1596.
    • (2003) Diabetes Care , vol.26 , Issue.5 , pp. 1589-1596
    • Ceriello, A.1
  • 7
    • 2442421194 scopus 로고    scopus 로고
    • Is oxidative stress the pathogenic mechanism underlying insulin resistance, diabetes, and cardiovascular disease? The common soil hypothesis revisited
    • Ceriello A, Motz E: Is oxidative stress the pathogenic mechanism underlying insulin resistance, diabetes, and cardiovascular disease? The common soil hypothesis revisited. Arterioscler Thromb Vasc Biol 2004, 24(5):816-823.
    • (2004) Arterioscler. Thromb. Vasc. Biol. , vol.24 , Issue.5 , pp. 816-823
    • Ceriello, A.1    Motz, E.2
  • 8
    • 0035668056 scopus 로고    scopus 로고
    • Diabetes-associated nitration of tyrosine and inactivation of succinyl-CoA:3-oxoacid CoA-transferase
    • Turko IV, Marcondes S, Murad F: Diabetes-associated nitration of tyrosine and inactivation of succinyl-CoA:3-oxoacid CoA-transferase. Am J Physiol Heart Circ Physiol 2001, 281(6):H2289-2294.
    • (2001) Am. J. Physiol. Heart Circ. Physiol. , vol.281 , Issue.6
    • Turko, I.V.1    Marcondes, S.2    Murad, F.3
  • 10
    • 0036796875 scopus 로고    scopus 로고
    • Oxidative stress and stress-activated signaling pathways: A unifying hypothesis of type 2 diabetes
    • Evans JL, Goldfine ID, Maddux BA, Grodsky GM: Oxidative stress and stress-activated signaling pathways: a unifying hypothesis of type 2 diabetes. Endocr Rev 2002, 23(5):599-622.
    • (2002) Endocr. Rev. , vol.23 , Issue.5 , pp. 599-622
    • Evans, J.L.1    Goldfine, I.D.2    Maddux, B.A.3    Grodsky, G.M.4
  • 11
    • 1342325376 scopus 로고    scopus 로고
    • Oxidative stress and antioxidant supplementation in the management of diabetic cardiovascular disease
    • Vega-Lopez S, Devaraj S, Jialal I: Oxidative stress and antioxidant supplementation in the management of diabetic cardiovascular disease. J Investig Med 2004, 52(1):24-32.
    • (2004) J. Investig. Med. , vol.52 , Issue.1 , pp. 24-32
    • Vega-Lopez, S.1    Devaraj, S.2    Jialal, I.3
  • 12
    • 0037219409 scopus 로고    scopus 로고
    • Are oxidative stress-activated signaling pathways mediators of insulin resistance and {beta}-cell dysfunction?
    • Evans JL, Goldfine ID, Maddux BA, Grodsky GM: Are oxidative stress-activated signaling pathways mediators of insulin resistance and {beta}-cell dysfunction? Diabetes 2003, 52(1):1-8.
    • (2003) Diabetes , vol.52 , Issue.1 , pp. 1-8
    • Evans, J.L.1    Goldfine, I.D.2    Maddux, B.A.3    Grodsky, G.M.4
  • 13
    • 0142055950 scopus 로고    scopus 로고
    • Oxidative stress and cardiovascular injury: Part I: Basic mechanisms and in vivo monitoring of ROS
    • Griendling KK, FitzGerald GA: Oxidative stress and cardiovascular injury: Part I: Basic mechanisms and in vivo monitoring of ROS. Circulation 2003, 108(16):1912-1916.
    • (2003) Circulation , vol.108 , Issue.16 , pp. 1912-1916
    • Griendling, K.K.1    FitzGerald, G.A.2
  • 14
    • 0242349764 scopus 로고    scopus 로고
    • Oxidative stress and cardiovascular injury: Part II: Animal and human studies
    • Griendling KK, FitzGerald GA: Oxidative stress and cardiovascular injury: Part II: animal and human studies. Circulation 2003, 108(17):2034-2040.
    • (2003) Circulation , vol.108 , Issue.17 , pp. 2034-2040
    • Griendling, K.K.1    FitzGerald, G.A.2
  • 15
    • 0348109425 scopus 로고    scopus 로고
    • Reactive oxygen species in the vasculature: Molecular and cellular mechanisms
    • Taniyama Y, Griendling KK: Reactive oxygen species in the vasculature: Molecular and cellular mechanisms. Hypertension 2003, 42(6):1075-1081.
    • (2003) Hypertension , vol.42 , Issue.6 , pp. 1075-1081
    • Taniyama, Y.1    Griendling, K.K.2
  • 17
    • 0036461688 scopus 로고    scopus 로고
    • The coronary circulation in diabetes: Influence of reactive oxygen species on K+ channel-mediated vasodilation
    • Liu Y, Gutterman DD: The coronary circulation in diabetes: influence of reactive oxygen species on K+ channel-mediated vasodilation. Vascul Pharmacol 2002, 38(1):43-49.
    • (2002) Vascul. Pharmacol. , vol.38 , Issue.1 , pp. 43-49
    • Liu, Y.1    Gutterman, D.D.2
  • 18
    • 0037195428 scopus 로고    scopus 로고
    • Peroxynitrite inhibits Ca2+-activated K+ channel activity in smooth muscle of human coronary arterioles
    • Liu Y, Terata K, Chai Q, Li H, Kleinman LH, Gutterman DD: Peroxynitrite inhibits Ca2+-activated K+ channel activity in smooth muscle of human coronary arterioles. Circ Res 2002, 91(11):1070-1076.
    • (2002) Circ. Res. , vol.91 , Issue.11 , pp. 1070-1076
    • Liu, Y.1    Terata, K.2    Chai, Q.3    Li, H.4    Kleinman, L.H.5    Gutterman, D.D.6
  • 19
    • 0034890040 scopus 로고    scopus 로고
    • Diabetic endothelial dysfunction: Role of reactive oxygen and nitrogen species production and poly(ADP-ribose) polymerase activation
    • Soriano FG, Virag L, Szabo C: Diabetic endothelial dysfunction: role of reactive oxygen and nitrogen species production and poly(ADP-ribose) polymerase activation. J Mol Med 2001, 79(8):437-448.
    • (2001) J. Mol. Med. , vol.79 , Issue.8 , pp. 437-448
    • Soriano, F.G.1    Virag, L.2    Szabo, C.3
  • 20
    • 1342322653 scopus 로고    scopus 로고
    • Increased prevalence of oxidant stress and inflammation in patients with moderate to severe chronic kidney disease
    • Oberg BP, McMenamin E, Lucas FL, McMonagle E, Morrow J, Ikizler TA, Himmelfarb J: Increased prevalence of oxidant stress and inflammation in patients with moderate to severe chronic kidney disease. Kidney Int 2004, 65(3):1009-1016.
    • (2004) Kidney Int. , vol.65 , Issue.3 , pp. 1009-1016
    • Oberg, B.P.1    McMenamin, E.2    Lucas, F.L.3    McMonagle, E.4    Morrow, J.5    Ikizler, T.A.6    Himmelfarb, J.7
  • 21
    • 0034640107 scopus 로고    scopus 로고
    • Vascular superoxide production by NAD(P)H oxidase: Association with endothelial dysfunction and clinical risk factors
    • Guzik TJ, West NE, Black E, McDonald D, Ratnatunga C, Pillai R, Channon KM: Vascular superoxide production by NAD(P)H oxidase: association with endothelial dysfunction and clinical risk factors. Circ Res 2000, 86(9):E85-90.
    • (2000) Circ. Res. , vol.86 , Issue.9
    • Guzik, T.J.1    West, N.E.2    Black, E.3    McDonald, D.4    Ratnatunga, C.5    Pillai, R.6    Channon, K.M.7
  • 22
    • 0037046214 scopus 로고    scopus 로고
    • Mechanisms of increased vascular superoxide production in human diabetes mellitus: Role of NAD(P)H oxidase and endothelial nitric oxide synthase
    • Guzik TJ, Mussa S, Gastaldi D, Sadowski J, Ratnatunga C, Pillai R, Channon KM: Mechanisms of increased vascular superoxide production in human diabetes mellitus: role of NAD(P)H oxidase and endothelial nitric oxide synthase. Circulation 2002, 105(14):1656-1662.
    • (2002) Circulation , vol.105 , Issue.14 , pp. 1656-1662
    • Guzik, T.J.1    Mussa, S.2    Gastaldi, D.3    Sadowski, J.4    Ratnatunga, C.5    Pillai, R.6    Channon, K.M.7
  • 24
    • 0141921796 scopus 로고    scopus 로고
    • Activities of xanthine oxidoreductase and antioxidant enzymes in different tissues of diabetic rats
    • Aliciguzel Y, Ozen I, Aslan M, Karayalcin U: Activities of xanthine oxidoreductase and antioxidant enzymes in different tissues of diabetic rats. J Lab Clin Med 2003, 142(3):172-177.
    • (2003) J. Lab. Clin. Med. , vol.142 , Issue.3 , pp. 172-177
    • Aliciguzel, Y.1    Ozen, I.2    Aslan, M.3    Karayalcin, U.4
  • 25
    • 0141755311 scopus 로고    scopus 로고
    • Translocation of glomerular p47phox and p67phox by protein kinase C-beta activation is required for oxidative stress in diabetic nephropathy
    • Kitada M, Koya D, Sugimoto T, Isono M, Araki S, Kashiwagi A, Haneda M: Translocation of glomerular p47phox and p67phox by protein kinase C-beta activation is required for oxidative stress in diabetic nephropathy. Diabetes 2003, 52(10):2603-2614.
    • (2003) Diabetes , vol.52 , Issue.10 , pp. 2603-2614
    • Kitada, M.1    Koya, D.2    Sugimoto, T.3    Isono, M.4    Araki, S.5    Kashiwagi, A.6    Haneda, M.7
  • 26
    • 0042864155 scopus 로고    scopus 로고
    • Increased expression of NAD(P)H oxidase subunits, NOX4 and p22phox, in the kidney of streptozotocin-induced diabetic rats and its reversibity by interventive insulin treatment
    • Etoh T, Inoguchi T, Kakimoto M, Sonoda N, Kobayashi K, Kuroda J, Sumimoto H, Nawata H: Increased expression of NAD(P)H oxidase subunits, NOX4 and p22phox, in the kidney of streptozotocin-induced diabetic rats and its reversibity by interventive insulin treatment. Diabetologia 2003, 46(10):1428-1437.
    • (2003) Diabetologia , vol.46 , Issue.10 , pp. 1428-1437
    • Etoh, T.1    Inoguchi, T.2    Kakimoto, M.3    Sonoda, N.4    Kobayashi, K.5    Kuroda, J.6    Sumimoto, H.7    Nawata, H.8
  • 28
    • 0036236158 scopus 로고    scopus 로고
    • Angiotensin II activation of the JAK/STAT pathway in mesangial cells is altered by high glucose
    • Amiri F, Shaw S, Wang X, Tang J, Waller JL, Eaton DC, Marrero MB: Angiotensin II activation of the JAK/STAT pathway in mesangial cells is altered by high glucose. Kidney Int 2002, 61(5):1605-1616.
    • (2002) Kidney Int. , vol.61 , Issue.5 , pp. 1605-1616
    • Amiri, F.1    Shaw, S.2    Wang, X.3    Tang, J.4    Waller, J.L.5    Eaton, D.C.6    Marrero, M.B.7
  • 29
    • 0842328003 scopus 로고    scopus 로고
    • Prevention of mitochondrial oxidative damage as a therapeutic strategy in diabetes
    • Green K, Brand MD, Murphy MP: Prevention of mitochondrial oxidative damage as a therapeutic strategy in diabetes. Diabetes 2004, 53(Suppl 1):S110-118.
    • (2004) Diabetes , vol.53 , Issue.1 SUPPL.
    • Green, K.1    Brand, M.D.2    Murphy, M.P.3
  • 31
    • 0035856980 scopus 로고    scopus 로고
    • Biochemistry and molecular cell biology of diabetic complications
    • Brownlee M: Biochemistry and molecular cell biology of diabetic complications. Nature 2001, 414(6865):813-820.
    • (2001) Nature , vol.414 , Issue.6865 , pp. 813-820
    • Brownlee, M.1
  • 33
    • 0042971701 scopus 로고    scopus 로고
    • Myocardial redox stress and remodeling in metabolic syndrome, type 2 diabetes mellitus, and congestive heart failure
    • Hayden MR, Tyagi SC: Myocardial redox stress and remodeling in metabolic syndrome, type 2 diabetes mellitus, and congestive heart failure. Med Sci Monit 2003, 9(7):SR35-52.
    • (2003) Med. Sci. Monit. , vol.9 , Issue.7
    • Hayden, M.R.1    Tyagi, S.C.2
  • 34
    • 20244361944 scopus 로고    scopus 로고
    • Antioxidative effects of exercise training in patients with chronic heart failure: Increase in radical scavenger enzyme activity in skeletal muscle
    • Linke A, Adams V, Schulze PC, Erbs S, Gielen S, Fiehn E, Mobius-Winkler S, Schubert A, Schuler G, Hambrecht R: Antioxidative effects of exercise training in patients with chronic heart failure: increase in radical scavenger enzyme activity in skeletal muscle. Circulation 2005, 111(14):1763-1770.
    • (2005) Circulation , vol.111 , Issue.14 , pp. 1763-1770
    • Linke, A.1    Adams, V.2    Schulze, P.C.3    Erbs, S.4    Gielen, S.5    Fiehn, E.6    Mobius-Winkler, S.7    Schubert, A.8    Schuler, G.9    Hambrecht, R.10
  • 35
    • 4143053663 scopus 로고    scopus 로고
    • Increased F2 isoprostane plasma levels in patients with congestive heart failure are correlated with antioxidant status and disease severity
    • Cristina Polidori M, Pratico D, Savino K, Rokach J, Stahl W, Mecocci P: Increased F2 isoprostane plasma levels in patients with congestive heart failure are correlated with antioxidant status and disease severity. J Card Fail 2004, 10(4):334-338.
    • (2004) J. Card. Fail. , vol.10 , Issue.4 , pp. 334-338
    • Cristina Polidori, M.1    Pratico, D.2    Savino, K.3    Rokach, J.4    Stahl, W.5    Mecocci, P.6
  • 38
    • 0036827017 scopus 로고    scopus 로고
    • Coenzyme Q10 improves blood pressure and glycaemic control: A controlled trial in subjects with type 2 diabetes
    • Hodgson JM, Watts GF, Playford DA, Burke V, Croft KD: Coenzyme Q10 improves blood pressure and glycaemic control: a controlled trial in subjects with type 2 diabetes. Eur J Clin Nutr 2002, 56(11):1137-1142.
    • (2002) Eur. J. Clin. Nutr. , vol.56 , Issue.11 , pp. 1137-1142
    • Hodgson, J.M.1    Watts, G.F.2    Playford, D.A.3    Burke, V.4    Croft, K.D.5
  • 39
    • 0348049904 scopus 로고    scopus 로고
    • Can coenzyme Q10 improve vascular function and blood pressure? Potential for effective therapeutic reduction in vascular oxidative stress
    • Hodgson JM, Watts GF: Can coenzyme Q10 improve vascular function and blood pressure? Potential for effective therapeutic reduction in vascular oxidative stress. Biofactors 2003, 18(1-4):129-136.
    • (2003) Biofactors , vol.18 , Issue.1-4 , pp. 129-136
    • Hodgson, J.M.1    Watts, G.F.2
  • 40
    • 0036207652 scopus 로고    scopus 로고
    • Coenzyme Q(10) improves endothelial dysfunction of the brachial artery in Type II diabetes mellitus
    • Watts GF, Playford DA, Croft KD, Ward NC, Mori TA, Burke V: Coenzyme Q(10) improves endothelial dysfunction of the brachial artery in Type II diabetes mellitus. Diabetologia 2002, 45(3):420-426.
    • (2002) Diabetologia , vol.45 , Issue.3 , pp. 420-426
    • Watts, G.F.1    Playford, D.A.2    Croft, K.D.3    Ward, N.C.4    Mori, T.A.5    Burke, V.6
  • 41
    • 0035808310 scopus 로고    scopus 로고
    • L-ascorbic acid potentiates endothelial nitric oxide synthesis via a chemical stabilization of tetrahydrobiopterin
    • Heller R, Unbehaun A, Schellenberg B, Mayer B, Werner-Felmayer G, Werner ER: L-ascorbic acid potentiates endothelial nitric oxide synthesis via a chemical stabilization of tetrahydrobiopterin. J Biol Chem 2001, 276(1):40-47.
    • (2001) J. Biol. Chem. , vol.276 , Issue.1 , pp. 40-47
    • Heller, R.1    Unbehaun, A.2    Schellenberg, B.3    Mayer, B.4    Werner-Felmayer, G.5    Werner, E.R.6
  • 42
    • 84984525423 scopus 로고
    • Effect of intake of exogenous vitamins C, E and beta-carotene on the antioxidative status in kidneys of rats with streptozotocin-induced diabetes
    • Mekinova D, Chorvathova V, Volkovova K, Staruchova M, Grancicova E, Klvanoca J, Ondreicka R: Effect of intake of exogenous vitamins C, E and beta-carotene on the antioxidative status in kidneys of rats with streptozotocin-induced diabetes. Nahrung 1995, 39(4):257-261.
    • (1995) Nahrung , vol.39 , Issue.4 , pp. 257-261
    • Mekinova, D.1    Chorvathova, V.2    Volkovova, K.3    Staruchova, M.4    Grancicova, E.5    Klvanoca, J.6    Ondreicka, R.7
  • 43
    • 1542544623 scopus 로고    scopus 로고
    • Effect of vitamin E and vitamin C supplementation of antioxidative state and renal glomerular basement membrane thickness in diabetic kidney
    • Kedziora-kornatowska K, Szram S, Kornatowski T, Szadujkis-Szadurski L, Kedziora J, Bartosz G: Effect of vitamin E and vitamin C supplementation of antioxidative state and renal glomerular basement membrane thickness in diabetic kidney. Exp Nephrology 2003, 95:134-143.
    • (2003) Exp. Nephrology , vol.95 , pp. 134-143
    • Kedziora-Kornatowska, K.1    Szram, S.2    Kornatowski, T.3    Szadujkis-Szadurski, L.4    Kedziora, J.5    Bartosz, G.6
  • 44
    • 0035174557 scopus 로고    scopus 로고
    • Effect of dietary vitamin E supplementation on vascular reactivity of thoracic aorta in streptozotocin-diabetic rats
    • Cinar M, Ulker S, Alper G, Evinc A: Effect of dietary vitamin E supplementation on vascular reactivity of thoracic aorta in streptozotocin-diabetic rats. Pharmacology 2001, 62(1):56-64.
    • (2001) Pharmacology , vol.62 , Issue.1 , pp. 56-64
    • Cinar, M.1    Ulker, S.2    Alper, G.3    Evinc, A.4
  • 45
    • 0034625764 scopus 로고    scopus 로고
    • Early changes in lipid peroxidation and antioxidative defense in rat retina
    • Obrosova I, Fathallah L, Greene D: Early changes in lipid peroxidation and antioxidative defense in rat retina. Eur J Pharm 2000, 398:139-146.
    • (2000) Eur. J. Pharm. , vol.398 , pp. 139-146
    • Obrosova, I.1    Fathallah, L.2    Greene, D.3
  • 46
    • 0034536369 scopus 로고    scopus 로고
    • Alpha-lipoic acid treatment ameliorates metabolic parameters, blood pressure, vascular reavtivity and morphology of vessels already damaged by streptozotocin-diabetes
    • Kocak G, Aktan F, Canbolat O, Ozogul C, Elberg S, Yildizoglu-Ari N, Karasu C: Alpha-lipoic acid treatment ameliorates metabolic parameters, blood pressure, vascular reavtivity and morphology of vessels already damaged by streptozotocin-diabetes. Diab Nutr Metab 2000, 13:308-318.
    • (2000) Diab. Nutr. Metab. , vol.13 , pp. 308-318
    • Kocak, G.1    Aktan, F.2    Canbolat, O.3    Ozogul, C.4    Elberg, S.5    Yildizoglu-Ari, N.6    Karasu, C.7
  • 47
    • 0035141065 scopus 로고    scopus 로고
    • Effects of coenzyme Q10 treatment on antioxidant pathways in normal and streptozotocin-induced diabetic rats
    • Rauscher F, Sanders R, Watkins JI: Effects of coenzyme Q10 treatment on antioxidant pathways in normal and streptozotocin-induced diabetic rats. J Biochem Mol Toxicol 2001, 15:41-46.
    • (2001) J. Biochem. Mol. Toxicol. , vol.15 , pp. 41-46
    • Rauscher, F.1    Sanders, R.2    Watkins, J.I.3
  • 48
    • 0037707713 scopus 로고    scopus 로고
    • Effects of alpha-lipoic acid on biomarkers of oxidative stress in streptozotic-induced diabetic rats
    • Maritim A, Sanders R, Watkins JI: Effects of alpha-lipoic acid on biomarkers of oxidative stress in streptozotic-induced diabetic rats. J Nutr Biochem 2003, 14(5):288-294.
    • (2003) J. Nutr. Biochem. , vol.14 , Issue.5 , pp. 288-294
    • Maritim, A.1    Sanders, R.2    Watkins, J.I.3
  • 49
    • 0346157986 scopus 로고    scopus 로고
    • Nitric oxide may prevent hypertension early in diabetes by counteracting renal actions of superoxide
    • Brands MW, Bell TD, Gibson B: Nitric oxide may prevent hypertension early in diabetes by counteracting renal actions of superoxide. Hypertension 2004, 43(1):57-63.
    • (2004) Hypertension , vol.43 , Issue.1 , pp. 57-63
    • Brands, M.W.1    Bell, T.D.2    Gibson, B.3
  • 50
    • 0033910718 scopus 로고    scopus 로고
    • Vitamin E supplementation improves endothelial function in type I diabetes mellitus: A randomized, placebo-controlled study
    • Skyrme-Jones RA, O'Brien RC, Berry KL, Meredith IT: Vitamin E supplementation improves endothelial function in type I diabetes mellitus: a randomized, placebo-controlled study. J Am Coll Cardiol 2000, 36(1):94-102.
    • (2000) J. Am. Coll. Cardiol. , vol.36 , Issue.1 , pp. 94-102
    • Skyrme-Jones, R.A.1    O'Brien, R.C.2    Berry, K.L.3    Meredith, I.T.4
  • 52
    • 0034792627 scopus 로고    scopus 로고
    • Double-blind, randomised study of the effect of combined treatment with vitamin C and E on albuminuria in Type 2 diabetic patients
    • Gaede P, Poulsen HE, Parving HH, Pedersen O: Double-blind, randomised study of the effect of combined treatment with vitamin C and E on albuminuria in Type 2 diabetic patients. Diabet Med 2001, 18(9):756-760.
    • (2001) Diabet. Med. , vol.18 , Issue.9 , pp. 756-760
    • Gaede, P.1    Poulsen, H.E.2    Parving, H.H.3    Pedersen, O.4
  • 53
    • 0034688195 scopus 로고    scopus 로고
    • Vitamin E supplementation and cardiovascular events in high-risk patients. The Heart Outcomes Prevention Evaluation Study Investigators
    • Yusuf S, Dagenais G, Pogue J, Bosch J, Sleight P: Vitamin E supplementation and cardiovascular events in high-risk patients. The Heart Outcomes Prevention Evaluation Study Investigators. N Engl J Med 2000, 342(3):154-160.
    • (2000) N. Engl. J. Med. , vol.342 , Issue.3 , pp. 154-160
    • Yusuf, S.1    Dagenais, G.2    Pogue, J.3    Bosch, J.4    Sleight, P.5
  • 54
    • 0034619027 scopus 로고    scopus 로고
    • Secondary prevention with antioxidants of cardiovascular disease in endstage renal disease (SPACE): Randomised placebo-controlled trial
    • Boaz M, Smetana S, Weinstein T, Matas Z, Gafter U, Iaina A, Knecht A, Weissgarten Y, Brunner D, Fainaru M, et al.: Secondary prevention with antioxidants of cardiovascular disease in endstage renal disease (SPACE): randomised placebo-controlled trial. Lancet 2000, 356(9237):1213-1218.
    • (2000) Lancet , vol.356 , Issue.9237 , pp. 1213-1218
    • Boaz, M.1    Smetana, S.2    Weinstein, T.3    Matas, Z.4    Gafter, U.5    Iaina, A.6    Knecht, A.7    Weissgarten, Y.8    Brunner, D.9    Fainaru, M.10
  • 55
  • 56
    • 0345411332 scopus 로고    scopus 로고
    • Primary prevention of cardiovascular events with low-dose aspirin and Vitamin E in Type 2 diabetic patients: Results of the Primary Prevention Project (PPP) trial
    • Sacco M, Pellegrini F, Roncaglioni MC, Avanzini F, Tognoni G, Nicolucci A: Primary prevention of cardiovascular events with low-dose aspirin and Vitamin E in Type 2 diabetic patients: Results of the Primary Prevention Project (PPP) trial. Diabetes Care 2003, 26(12):3264-3272.
    • (2003) Diabetes Care , vol.26 , Issue.12 , pp. 3264-3272
    • Sacco, M.1    Pellegrini, F.2    Roncaglioni, M.C.3    Avanzini, F.4    Tognoni, G.5    Nicolucci, A.6
  • 57
    • 0035916235 scopus 로고    scopus 로고
    • Effects of ramipril and vitamin E on atherosclerosis: The study to evaluate carotid ultrasound changes in patients treated with ramipril and vitamin E (SECURE)
    • Lonn EM, Yusuf S, Dzavik V, Doris CI, Yi Q, Smith S, Moore-Cox A, Bosch J, Riley WA, Teo KK: Effects of ramipril and vitamin E on atherosclerosis: The study to evaluate carotid ultrasound changes in patients treated with ramipril and vitamin E (SECURE). Circulation 2001, 103(7):919-925.
    • (2001) Circulation , vol.103 , Issue.7 , pp. 919-925
    • Lonn, E.M.1    Yusuf, S.2    Dzavik, V.3    Doris, C.I.4    Yi, Q.5    Smith, S.6    Moore-Cox, A.7    Bosch, J.8    Riley, W.A.9    Teo, K.K.10
  • 58
    • 0036834582 scopus 로고    scopus 로고
    • Effects of vitamin E on cardiovascular and microvascular outcomes in high-risk patients with diabetes: Results of the HOPE study and MICRO-HOPE substudy
    • Lonn E, Yusuf S, Hoogwerf B, Pogue J, Yi Q, Zinman B, Bosch J, Dagenais G, Mann JFE, Gerstein HC: Effects of vitamin E on cardiovascular and microvascular outcomes in high-risk patients with diabetes: Results of the HOPE study and MICRO-HOPE substudy. Diabetes Care 2002, 25(11):1919-1927.
    • (2002) Diabetes Care , vol.25 , Issue.11 , pp. 1919-1927
    • Lonn, E.1    Yusuf, S.2    Hoogwerf, B.3    Pogue, J.4    Yi, Q.5    Zinman, B.6    Bosch, J.7    Dagenais, G.8    Mann, J.F.E.9    Gerstein, H.C.10
  • 59
    • 0028845524 scopus 로고
    • Treatment of symptomatic diabetic peripheral neuropathy with the anti-oxidant alpha-lipoic acid. A 3-week multicentre randomized controlled trial (ALADIN Study)
    • Ziegler D, Hanefeld M, Ruhnau KJ, Meissner HP, Lobisch M, Schutte K, Gries FA: Treatment of symptomatic diabetic peripheral neuropathy with the anti-oxidant alpha-lipoic acid. A 3-week multicentre randomized controlled trial (ALADIN Study). Diabetologia 1995, 38(12):1425-1433.
    • (1995) Diabetologia , vol.38 , Issue.12 , pp. 1425-1433
    • Ziegler, D.1    Hanefeld, M.2    Ruhnau, K.J.3    Meissner, H.P.4    Lobisch, M.5    Schutte, K.6    Gries, F.A.7
  • 60
    • 0032881613 scopus 로고    scopus 로고
    • Treatment of diabetic polyneuropathy with the antioxidant thioctic acid (alpha-lipoic acid): A two year multicenter randomized double-blind placebo-controlled trial (ALADIN II) Alpha Lipoic Acid in Diabetic Neuropathy
    • Reljanovic M, Reichel G, Rett K, Lobisch M, Schuette K, Moller W, Tritschler HJ, Mehnert H: Treatment of diabetic polyneuropathy with the antioxidant thioctic acid (alpha-lipoic acid): a two year multicenter randomized double-blind placebo-controlled trial (ALADIN II). Alpha Lipoic Acid in Diabetic Neuropathy. Free Radic Res 1999, 31(3):171-179.
    • (1999) Free Radic. Res. , vol.31 , Issue.31 , pp. 71-179
    • Reljanovic, M.1    Reichel, G.2    Rett, K.3    Lobisch, M.4    Schuette, K.5    Moller, W.6    Tritschler, H.J.7    Mehnert, H.8
  • 61
    • 0032788081 scopus 로고    scopus 로고
    • Treatment of symptomatic diabetic polyneuropathy with the antioxidant alpha-lipoic acid: A 7-month multicenter randomized controlled trial (ALADIN III Study). ALADIN III Study Group. Alpha-Lipoic Acid in Diabetic Neuropathy
    • Ziegler D, Hanefeld M, Ruhnau K, Hasche H, Lobisch M, Schutte K, Kerum G, Malessa R: Treatment of symptomatic diabetic polyneuropathy with the antioxidant alpha-lipoic acid: a 7-month multicenter randomized controlled trial (ALADIN III Study). ALADIN III Study Group. Alpha-Lipoic Acid in Diabetic Neuropathy. Diabetes Care 1999, 22(8):1296-1301.
    • (1999) Diabetes Care , vol.22 , Issue.8 , pp. 1296-1301
    • Ziegler, D.1    Hanefeld, M.2    Ruhnau, K.3    Hasche, H.4    Lobisch, M.5    Schutte, K.6    Kerum, G.7    Malessa, R.8
  • 62
    • 0031028636 scopus 로고    scopus 로고
    • Effects of treatment with the antioxidant alpha-lipoic acid on cardiac autonomic neuropathy in NIDDM patients. A 4-month randomized controlled multicenter trial (DEKAN Study). Deutsche Kardiale Autonome Neuropathie
    • Ziegler D, Schatz H, Conrad F, Gries FA, Ulrich H, Reichel G: Effects of treatment with the antioxidant alpha-lipoic acid on cardiac autonomic neuropathy in NIDDM patients. A 4-month randomized controlled multicenter trial (DEKAN Study). Deutsche Kardiale Autonome Neuropathie. Diabetes Care 1997, 20(3):369-373.
    • (1997) Diabetes Care , vol.20 , Issue.3 , pp. 369-373
    • Ziegler, D.1    Schatz, H.2    Conrad, F.3    Gries, F.A.4    Ulrich, H.5    Reichel, G.6
  • 64
    • 1242337352 scopus 로고    scopus 로고
    • Treatment of symptomatic diabetic polyneuropathy with the antioxidant alpha-lipoic acid: A meta-analysis
    • Ziegler D, Nowak H, Kempler P, Vargha P, Low PA: Treatment of symptomatic diabetic polyneuropathy with the antioxidant alpha-lipoic acid: a meta-analysis. Diabet Med 2004, 21(2):114-121.
    • (2004) Diabet. Med. , vol.21 , Issue.2 , pp. 114-121
    • Ziegler, D.1    Nowak, H.2    Kempler, P.3    Vargha, P.4    Low, P.A.5
  • 66
    • 0942276496 scopus 로고    scopus 로고
    • PPARgamma activation, by reducing oxidative stress, increases NO bioavailability in coronary arterioles of mice with Type 2 diabetes
    • Bagi Z, Koller A, Kaley G: PPARgamma activation, by reducing oxidative stress, increases NO bioavailability in coronary arterioles of mice with Type 2 diabetes. Am J Physiol 2004, 286(2):H742-748.
    • (2004) Am. J. Physiol. , vol.286 , Issue.2
    • Bagi, Z.1    Koller, A.2    Kaley, G.3
  • 67
    • 0034646746 scopus 로고    scopus 로고
    • Dietary troglitazone decreases oxidative stress in early stage type II diabetic rats
    • Fukui T, Noma T, Mizushige K, Aki Y, Kimura S, Abe Y: Dietary troglitazone decreases oxidative stress in early stage type II diabetic rats. Life Sci 2000, 66(21):2043-2049.
    • (2000) Life Sci. , vol.66 , Issue.21 , pp. 2043-2049
    • Fukui, T.1    Noma, T.2    Mizushige, K.3    Aki, Y.4    Kimura, S.5    Abe, Y.6
  • 70
    • 9144256731 scopus 로고    scopus 로고
    • Contribution of vascular NAD(P)H oxidase to endothelial dysfunction in heart failure and the therapeutic effects of HMG-CoA reductase inhibitor
    • Takayama T, Wada A, Tsutamoto T, Ohnishi M, Fujii M, Isono T, Horie M: Contribution of vascular NAD(P)H oxidase to endothelial dysfunction in heart failure and the therapeutic effects of HMG-CoA reductase inhibitor. Circ J 2004, 68(11):1067-1075.
    • (2004) Circ. J. , vol.68 , Issue.11 , pp. 1067-1075
    • Takayama, T.1    Wada, A.2    Tsutamoto, T.3    Ohnishi, M.4    Fujii, M.5    Isono, T.6    Horie, M.7
  • 71
    • 4143102291 scopus 로고    scopus 로고
    • Antioxidant effects of statins via S-nitrosylation and activation of thioredoxin in endothelial cells: A novel vasculoprotective function of statins
    • Haendeler J, Hoffmann J, Zeiher AM, Dimmeler S: Antioxidant effects of statins via S-nitrosylation and activation of thioredoxin in endothelial cells: a novel vasculoprotective function of statins. Circulation 2004, 110(7):856-861.
    • (2004) Circulation , vol.110 , Issue.7 , pp. 856-861
    • Haendeler, J.1    Hoffmann, J.2    Zeiher, A.M.3    Dimmeler, S.4
  • 72
    • 0242721909 scopus 로고    scopus 로고
    • Simvastatin modulates expression of the PON1 gene and increases serum paraoxonase: A role for sterol regulatory element-binding protein-2
    • Deakin S, Leviev I, Guernier S, James RW: Simvastatin modulates expression of the PON1 gene and increases serum paraoxonase: a role for sterol regulatory element-binding protein-2. Arterioscler Thromb Vasc Biol 2003, 23(11):2083-2089.
    • (2003) Arterioscler. Thromb. Vasc. Biol. , vol.23 , Issue.11 , pp. 2083-2089
    • Deakin, S.1    Leviev, I.2    Guernier, S.3    James, R.W.4
  • 73
    • 4444333896 scopus 로고    scopus 로고
    • Reactive oxygen species and angiotensin II signaling in vascular cells - Implications in cardiovascular disease
    • Touyz RM: Reactive oxygen species and angiotensin II signaling in vascular cells - implications in cardiovascular disease. Braz J Med Biol Res 2004, 37(8):1263-1273.
    • (2004) Braz. J. Med. Biol. Res. , vol.37 , Issue.8 , pp. 1263-1273
    • Touyz, R.M.1
  • 74
    • 0032737361 scopus 로고    scopus 로고
    • Ang II-stimulated superoxide production is mediated via phospholipase D in human vascular smooth muscle cells
    • Touyz RM, Schiffrin EL: Ang II-stimulated superoxide production is mediated via phospholipase D in human vascular smooth muscle cells. Hypertension 1999, 34(4 Pt 2):976-982.
    • (1999) Hypertension , vol.34 , Issue.4 PART 2 , pp. 976-982
    • Touyz, R.M.1    Schiffrin, E.L.2
  • 75
    • 0034770786 scopus 로고    scopus 로고
    • Renin angiotensin system inhibition is associated with reduced free radical concentrations in arteries of patients with coronary heart disease
    • Berry C, Anderson N, Kirk AJ, Dominiczak AF, McMurray JJ: Renin angiotensin system inhibition is associated with reduced free radical concentrations in arteries of patients with coronary heart disease. Heart 2001, 86(2):217-220.
    • (2001) Heart , vol.86 , Issue.2 , pp. 217-220
    • Berry, C.1    Anderson, N.2    Kirk, A.J.3    Dominiczak, A.F.4    McMurray, J.J.5
  • 76
    • 0037197722 scopus 로고    scopus 로고
    • Is the oxidative modification hypothesis relevant to human atherosclerosis? Do the antioxidant trials conducted to date refute the hypothesis?
    • Steinberg D, Witztum JL: Is the oxidative modification hypothesis relevant to human atherosclerosis? Do the antioxidant trials conducted to date refute the hypothesis? Circulation 2002, 105(17):2107-2111.
    • (2002) Circulation , vol.105 , Issue.17 , pp. 2107-2111
    • Steinberg, D.1    Witztum, J.L.2
  • 77
    • 0035101472 scopus 로고    scopus 로고
    • Antioxidant therapy: A new pharmacological approach in shock, inflammation, and ischemia/reperfusion injury
    • Cuzzocrea S, Riley DP, Caputi AP, Salvemini D: Antioxidant therapy: A new pharmacological approach in shock, inflammation, and ischemia/reperfusion injury. Pharmacol Rev 2001, 53(1):135-159.
    • (2001) Pharmacol. Rev. , vol.53 , Issue.1 , pp. 135-159
    • Cuzzocrea, S.1    Riley, D.P.2    Caputi, A.P.3    Salvemini, D.4
  • 78
    • 0036821898 scopus 로고    scopus 로고
    • Part I: Pathogenetic role of peroxynitrite in the development of diabetes and diabetic vascular complications: Studies with FP15, a novel potent peroxynitrite decomposition catalyst
    • Szabo C, Mabley JG, Moeller SM, Shimanovich R, Pacher P, Virag L, Soriano FG, Van Duzer JH, Williams W, Salzman AL, et al.: Part I: pathogenetic role of peroxynitrite in the development of diabetes and diabetic vascular complications: studies with FP15, a novel potent peroxynitrite decomposition catalyst. Mol Med 2002, 8(10):571-580.
    • (2002) Mol. Med. , vol.8 , Issue.10 , pp. 571-580
    • Szabo, C.1    Mabley, J.G.2    Moeller, S.M.3    Shimanovich, R.4    Pacher, P.5    Virag, L.6    Soriano, F.G.7    Van Duzer, J.H.8    Williams, W.9    Salzman, A.L.10


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