Nitric oxide-mediated oxidative damage and the progressive demise of motor neurons in ALS

Neurotoxicity Research

Volumn 22, Issue 4, 2012, Pages 251-264

  Drechsel, Derek A ^a   Estévez, Alvaro G ^b   Barbeito, Luis ^c,d   Beckman, Joseph S ^a,e  

^a OREGON STATE UNIVERSITY   (United States)

^b UNIVERSITY OF CENTRAL FLORIDA COLLEGE OF MEDICINE   (United States)

^c INSTITUTO DE INVESTIGACIONES BIOLÓGICAS CLEMENTE ESTABLE   (Uruguay)

^d INSTITUT PASTEUR DE MONTEVIDEO   (Uruguay)

^e OREGON STATE UNIVERSITY   (United States)

Author keywords

Amyotrophic lateral sclerosis; Neurodegeneration; Nitric oxide; Peroxynitrite; Protein nitration

Indexed keywords

COPPER ZINC SUPEROXIDE DISMUTASE; GUANOSINE PHOSPHATE; MANGANESE SUPEROXIDE DISMUTASE; NEUROFILAMENT L PROTEIN; NEUROFILAMENT PROTEIN; NITRIC OXIDE; PEROXYNITRITE; PROTEIN PRECURSOR; REACTIVE OXYGEN METABOLITE; SUPEROXIDE; UNCLASSIFIED DRUG;

AMYOTROPHIC LATERAL SCLEROSIS; APOPTOSIS; BIOSYNTHESIS; BRAIN MITOCHONDRION; CELL STRESS; CELL SURVIVAL; DISEASE ACTIVITY; DISEASE COURSE; DISORDERS OF MITOCHONDRIAL FUNCTIONS; GLIA CELL; HUMAN; MOTOR NEURON DISEASE; NERVE CELL LESION; NERVE CELL NECROSIS; NERVE CELL STIMULATION; NERVE DEGENERATION; NEUROMODULATION; NEUROTOXICITY; NITRATION; NONHUMAN; OXIDATION REDUCTION REACTION; OXIDATIVE STRESS; PATHOGENESIS; PATHOPHYSIOLOGY; PHENOTYPE; PRIORITY JOURNAL; PROTEIN FUNCTION; REVIEW; SIGNAL TRANSDUCTION;

AMYOTROPHIC LATERAL SCLEROSIS; ANIMALS; APOPTOSIS; HUMANS; MODELS, BIOLOGICAL; MOTOR NEURONS; NITRIC OXIDE; OXIDATIVE STRESS; SUPEROXIDE DISMUTASE;

EID: 84870299231     PISSN: 10298428     EISSN: 14763524     Source Type: Journal    
DOI: 10.1007/s12640-012-9322-y     Document Type: Review

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