Amplification and demultiplexing in insulin-regulated Akt protein kinase pathway in adipocytes

Journal of Biological Chemistry

Volumn 287, Issue 9, 2012, Pages 6128-6138

  Tan, Shi Xiong ^a   Ng, Yvonne ^a   Meoli, Christopher C ^a   Kumar, Ansu ^c   Khoo, Poh Sim ^d   Fazakerley, Daniel J ^a   Junutula, Jagath R ^d   Vali, Shireen ^c   James, David E ^a,b   Stöckli, Jacqueline ^a  

^a GARVAN INSTITUTE OF MEDICAL RESEARCH   (Australia)

^b UNIVERSITY OF NEW SOUTH WALES   (Australia)

^c CELLWORKS GROUP INC   (United States)

^d GENENTECH INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

3T3-L1 ADIPOCYTES; ADIPOCYTES; AKT PHOSPHORYLATION; DOWNSTREAM COMPONENTS; DYNAMIC RANGE; GENETIC MANIPULATIONS; HIGHLY SENSITIVE; INSULIN REGULATION; INSULIN SIGNALING; PROTEIN KINASE PATHWAYS; PROTEIN SYNTHESIS; THRESHOLD LEVELS;

DEMULTIPLEXING; PHOSPHORYLATION;

INSULIN;

AS160 PROTEIN; GLUCOSE TRANSPORTER 4; GLYCOGEN SYNTHASE KINASE 3; GUANOSINE TRIPHOSPHATASE ACTIVATING PROTEIN; INSULIN; MAMMALIAN TARGET OF RAPAMYCIN; PROTEIN KINASE B; TRANSCRIPTION FACTOR FKHR; TUBERIN; UNCLASSIFIED DRUG;

ADIPOCYTE; ARTICLE; CELL MEMBRANE; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME SUBSTRATE; PRIORITY JOURNAL; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; PROTEIN SYNTHESIS; PROTEIN TRANSPORT; SIGNAL TRANSDUCTION;

3T3-L1 CELLS; ADIPOCYTES; ANIMALS; ANTIBIOTICS, ANTINEOPLASTIC; COMPUTER SIMULATION; ENERGY METABOLISM; GLUCOSE TRANSPORTER TYPE 4; HYPOGLYCEMIC AGENTS; INSULIN; INSULIN RECEPTOR SUBSTRATE PROTEINS; INSULIN RESISTANCE; MICE; NONLINEAR DYNAMICS; PHOSPHORYLATION; PLATELET-DERIVED GROWTH FACTOR; PROTO-ONCOGENE PROTEINS C-AKT; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; SIROLIMUS; TOR SERINE-THREONINE KINASES;

EID: 84863127179     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M111.318238     Document Type: Article

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