Diabetes and mitochondrial function: Role of hyperglycemia and oxidative stress

Toxicology and Applied Pharmacology

Volumn 212, Issue 2, 2006, Pages 167-178

  Rolo, Anabela P ^a   Palmeira, Carlos M ^a  

^a UNIVERSITY OF COIMBRA   (Portugal)

Author keywords

Hyperglycemia; Mitochondria; Oxidative stress; PGC 1 ; ROS; UCP

Indexed keywords

AMINOGUANIDINE; ANTIOXIDANT; DIACYLGLYCEROL; FARNESOID X RECEPTOR; GLITAZONE DERIVATIVE; GLUCOSE; GLUCOSE TRANSPORTER; HEXOSAMINE; INSULIN; MITOCHONDRIAL DNA; NC 2100; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE INHIBITOR; PHOSPHOENOLPYRUVATE CARBOXYKINASE (GTP); POLYOL; PROTEIN KINASE C; PYRIDOXAMINE; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE; SUPEROXIDE; TROGLITAZONE; UBIDECARENONE; UNCLASSIFIED DRUG; UNCOUPLING PROTEIN 1; UNCOUPLING PROTEIN 2; UNCOUPLING PROTEIN 3;

BIOSYNTHESIS; CARBOHYDRATE METABOLISM; CELL DAMAGE; CLINICAL TRIAL; DIABETES MELLITUS; DIABETIC NEPHROPATHY; DIABETIC NEUROPATHY; DIABETIC RETINOPATHY; DRUG TARGETING; ENZYME ACTIVATION; FATTY ACID OXIDATION; GLUCOSE BLOOD LEVEL; GLUCOSE METABOLISM; GLUCOSE TRANSPORT; GLYCATION; HEART MITOCHONDRION; HERITABILITY; HUMAN; HYPERGLYCEMIA; INSULIN RELEASE; LIPID PEROXIDATION; LIVER MITOCHONDRION; MEMBRANE PERMEABILITY; MITOCHONDRIAL MEMBRANE; MITOCHONDRIAL RESPIRATION; MITOCHONDRION; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; OXIDATIVE STRESS; PANCREAS ISLET BETA CELL; PATHOGENESIS; PROTEIN ANALYSIS; PROTEIN FUNCTION; REGULATORY MECHANISM; REVIEW; TRANSCRIPTION REGULATION;

ANIMALS; DIABETES MELLITUS; GENE EXPRESSION REGULATION; GLUCOSE; HUMANS; HYPERGLYCEMIA; HYPOGLYCEMIC AGENTS; INSULIN; INSULIN-SECRETING CELLS; MITOCHONDRIA; OXIDATIVE STRESS; UNCOUPLING AGENTS;

EID: 33645765312     PISSN: 0041008X     EISSN: 10960333     Source Type: Journal    
DOI: 10.1016/j.taap.2006.01.003     Document Type: Review

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