RNA oxidation in Alzheimer disease and related neurodegenerative disorders

Acta Neuropathologica

Volumn 118, Issue 1, 2009, Pages 151-166

  Nunomura, Akihiko ^a   Hofer, Tim ^b   Moreira, Paula I ^c   Castellani, Rudy J ^d   Smith, Mark A ^e   Perry, George ^e,f  

^a UNIVERSITY OF YAMANASHI   (Japan)

^b UNIVERSITY OF FLORIDA   (United States)

^c UNIVERSITY OF COIMBRA   (Portugal)

^d UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

^e CASE WESTERN RESERVE UNIVERSITY   (United States)

^f University of San Antonio   (United States)

Author keywords

8 Hydroxyguanosine; Alzheimer disease; Neurodegeneration; Nucleic acids; Oxidative stress; RNA

Indexed keywords

8 HYDROXYDEOXYGUANOSINE; 8 HYDROXYGUANOSINE; ALPHA SYNUCLEIN; AMYLOID BETA PROTEIN; APOLIPOPROTEIN E4; CELL PROTEIN; COPPER ZINC SUPEROXIDE DISMUTASE; DJ 1 PROTEIN; GUANOSINE DERIVATIVE; MESSENGER RNA; MICRORNA; NEUROTOXIN; NUDIX HYDROLASE; PARKIN; POLYRIBONUCLEOTIDE NUCLEOTIDYLTRANSFERASE; PRESENILIN 1; PRESENILIN 2; PROTEIN MUTT HOMOLOGUE 1; PROTEIN NUDIX 5; REACTIVE OXYGEN METABOLITE; RIBONUCLEASE; UNCLASSIFIED DRUG; UNTRANSLATED RNA; Y BOX BINDING PROTEIN 1;

AGING; ALZHEIMER DISEASE; AMYOTROPHIC LATERAL SCLEROSIS; CELL AGGREGATION; COGNITIVE DEFECT; DIFFUSE LEWY BODY DISEASE; GENE EXPRESSION REGULATION; GENE MUTATION; GENETIC DAMAGE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HYPOXIA; IMMUNOBLOTTING; NERVE CELL CULTURE; NERVE CELL LESION; NERVE DEGENERATION; NEUROPATHOLOGY; NONHUMAN; OXIDATION; OXIDATIVE STRESS; PARKINSON DISEASE; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DEGRADATION; PROTEIN MODIFICATION; REVIEW; RNA DAMAGE; RNA OXIDATION; RNA REPAIR; RNA TRANSLATION; SENILE PLAQUE; SUBACUTE SCLEROSING PANENCEPHALITIS; TRANSGENIC MOUSE; TRAUMATIC BRAIN INJURY;

AGING; ALZHEIMER DISEASE; ANIMALS; BRAIN; DISEASE MODELS, ANIMAL; DNA; GUANOSINE; HUMANS; HYPOXIA, BRAIN; NEURODEGENERATIVE DISEASES; NEURONS; OXIDATION-REDUCTION; OXIDATIVE STRESS; REACTIVE OXYGEN SPECIES; RNA; SUPEROXIDE DISMUTASE;

EID: 67349251839     PISSN: 00016322     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00401-009-0508-1     Document Type: Review

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