메뉴 건너뛰기




Volumn 12, Issue 14, 2011, Pages 2096-2102

Role of advanced glycation end products (AGEs) in osteoporosis in diabetes

Author keywords

AGEs; Osteoporosis; Oxidative stress; RAGE

Indexed keywords

ADVANCED GLYCATION END PRODUCT; ADVANCED GLYCATION END PRODUCT RECEPTOR; ALKALINE PHOSPHATASE; BISPHOSPHONIC ACID DERIVATIVE; CASPASE 3; CASPASE 8; CASPASE 9; ESTRADIOL; INTERLEUKIN 1BETA; MACROPHAGE INFLAMMATORY PROTEIN 1ALPHA; OSTEOCALCIN; PARATHYROID HORMONE; PENTOSIDINE; RALOXIFENE; REACTIVE OXYGEN METABOLITE; SELECTIVE ESTROGEN RECEPTOR MODULATOR; STRESS ACTIVATED PROTEIN KINASE; SYNAPTOPHYSIN;

EID: 84855833476     PISSN: 13894501     EISSN: 18735592     Source Type: Journal    
DOI: 10.2174/138945011798829456     Document Type: Review
Times cited : (141)

References (78)
  • 1
    • 0242647810 scopus 로고    scopus 로고
    • NIH Consensus Statement
    • Osteoporosis Prevention, Diagnosis and Therapy: NIH Consensus Statement 2000; 17: 1-36. http://consensus.nih.gov/2000/ 2000Osteoporosis111html.htm
    • (2000) Osteoporosis Prevention, Diagnosis and Therapy , vol.17 , pp. 1-36
  • 2
    • 79953751008 scopus 로고    scopus 로고
    • Osteoporosis: Now and the future
    • Rachner TD, Khosla S, Hofbauer LC. Osteoporosis: now and the future. Lancet 2011; 377: 1276-87.
    • (2011) Lancet , vol.377 , pp. 1276-1287
    • Rachner, T.D.1    Khosla, S.2    Hofbauer, L.C.3
  • 4
    • 79960154986 scopus 로고    scopus 로고
    • Diabetes and bone health: The relationship between diabetes and osteoporosis-associated fractures
    • doi: 10.1002/dmrr.1197
    • Kurra S, Siris E. Diabetes and bone health: the relationship between diabetes and osteoporosis-associated fractures. Diabetes Metab Res Rev 2011; doi: 10.1002/dmrr.1197.
    • (2011) Diabetes Metab Res Rev
    • Kurra, S.1    Siris, E.2
  • 5
    • 33847629923 scopus 로고    scopus 로고
    • Discrepancies in bone mineral density and fracture risk in patients with type 1 and type 2 diabetes--a meta-analysis
    • Vestergaard P. Discrepancies in bone mineral density and fracture risk in patients with type 1 and type 2 diabetes--a meta-analysis. Osteoporos Int 2007; 18: 427-44.
    • (2007) Osteoporos Int , vol.18 , pp. 427-444
    • Vestergaard, P.1
  • 10
    • 0023950461 scopus 로고
    • Advanced glycosylation end products in tissue and the biochemical basis of diabetic complications
    • Brownlee M, Cerami A, Vlassara H. Advanced glycosylation end products in tissue and the biochemical basis of diabetic complications. N Engl J Med 1988; 318: 1315-21.
    • (1988) N Engl J Med , vol.318 , pp. 1315-1321
    • Brownlee, M.1    Cerami, A.2    Vlassara, H.3
  • 11
    • 0036167208 scopus 로고    scopus 로고
    • Diabetes and advanced glycation endproducts
    • Vlassara H, Palace MR. Diabetes and advanced glycation endproducts. J Intern Med 2002; 251: 87-101.
    • (2002) J Intern Med , vol.251 , pp. 87-101
    • Vlassara, H.1    Palace, M.R.2
  • 12
    • 21044443182 scopus 로고    scopus 로고
    • Diabetic vascular complications: Pathophysiology, biochemical basis and potential therapeutic strategy
    • Yamagishi S, Imaizumi T. Diabetic vascular complications: pathophysiology, biochemical basis and potential therapeutic strategy. Curr Pharm Des 2005; 11: 2279-99.
    • (2005) Curr Pharm Des , vol.11 , pp. 2279-2299
    • Yamagishi, S.1    Imaizumi, T.2
  • 13
    • 0025945553 scopus 로고
    • Formation of pentosidine during nonenzymatic browning of proteins by glucose. Identification of glucose and other carbohydrates as possible precursors of pentosidine in vivo
    • Dyer DG, Blackledge JA, Thorpe SR, Baynes JW. Formation of pentosidine during nonenzymatic browning of proteins by glucose. Identification of glucose and other carbohydrates as possible precursors of pentosidine in vivo. J Biol Chem 1991; 266: 11654-60.
    • (1991) J Biol Chem , vol.266 , pp. 11654-60
    • Dyer, D.G.1    Blackledge, J.A.2    Thorpe, S.R.3    Baynes, J.W.4
  • 14
    • 70149123804 scopus 로고    scopus 로고
    • Vascular calcification and bone disease: The calcification paradox
    • Persy V, D'Haese P. Vascular calcification and bone disease: the calcification paradox. Trends Mol Med 2009; 15: 405-16.
    • (2009) Trends Mol Med , vol.15 , pp. 405-416
    • Persy, V.1    D'Haese, P.2
  • 16
    • 79952707168 scopus 로고    scopus 로고
    • Role of advanced glycation end products (AGEs) and receptor for AGEs (RAGE) in vascular damage in diabetes
    • Yamagishi S. Role of advanced glycation end products (AGEs) and receptor for AGEs (RAGE) in vascular damage in diabetes. Exp Gerontol 2011; 46: 217-24.
    • (2011) Exp Gerontol , vol.46 , pp. 217-224
    • Yamagishi, S.1
  • 17
    • 0037038819 scopus 로고    scopus 로고
    • Receptor for advanced glycation endproducts: A multiligand receptor magnifying cell stress in diverse pathologic settings
    • Stern D, Yan SD, Yan SF, Schmidt AM. Receptor for advanced glycation endproducts: a multiligand receptor magnifying cell stress in diverse pathologic settings. Adv Drug Deliv Rev 2002; 54: 1615-25.
    • (2002) Adv Drug Deliv Rev , vol.54 , pp. 1615-1625
    • Stern, D.1    Yan, S.D.2    Yan, S.F.3    Schmidt, A.M.4
  • 18
    • 0032029363 scopus 로고    scopus 로고
    • AGEs and their interaction with AGE-receptors in vascular disease and diabetes mellitus. I. The AGE concept
    • Bierhaus A, Hofmann MA, Ziegler R, Nawroth PP. AGEs and their interaction with AGE-receptors in vascular disease and diabetes mellitus. I. The AGE concept. Cardiovasc Res 1998; 37: 586-600.
    • (1998) Cardiovasc Res , vol.37 , pp. 586-600
    • Bierhaus, A.1    Hofmann, M.A.2    Ziegler, R.3    Nawroth, P.P.4
  • 19
    • 77954716681 scopus 로고    scopus 로고
    • Smooth muscle cell pathophysiology and advanced glycation end products (AGEs)
    • Yamagishi S, Matsui T. Smooth muscle cell pathophysiology and advanced glycation end products (AGEs). Curr Drug Targets 2010; 11: 875-81.
    • (2010) Curr Drug Targets , vol.11 , pp. 875-881
    • Yamagishi, S.1    Matsui, T.2
  • 20
    • 80052074207 scopus 로고    scopus 로고
    • Activation of Receptor for Advanced Glycation End Products Induces Osteogenic Differentiation of Vascular Smooth Muscle Cells
    • (in press)
    • Suga T, Iso T, Shimizu T, et al. Activation of Receptor for Advanced Glycation End Products Induces Osteogenic Differentiation of Vascular Smooth Muscle Cells. J Atheroscler Thromb 2011 (in press)
    • (2011) J Atheroscler Thromb
    • Suga, T.1    Iso, T.2    Shimizu, T.3
  • 22
    • 26444480186 scopus 로고    scopus 로고
    • Possible participation of advanced glycation end products in the pathogenesis of osteoporosis in diabetic patients
    • Yamagishi S, Nakamura K, Inoue H. Possible participation of advanced glycation end products in the pathogenesis of osteoporosis in diabetic patients. Med Hypotheses 2005; 65: 1013-5.
    • (2005) Med Hypotheses , vol.65 , pp. 1013-1015
    • Yamagishi, S.1    Nakamura, K.2    Inoue, H.3
  • 23
    • 33746760406 scopus 로고    scopus 로고
    • Glycation endproducts in osteoporosis--is there a pathophysiologic importance?
    • Hein GE. Glycation endproducts in osteoporosis--is there a pathophysiologic importance? Clin Chim Acta 2006; 371: 32-6.
    • (2006) Clin Chim Acta , vol.371 , pp. 32-36
    • Hein, G.E.1
  • 24
    • 23744452766 scopus 로고    scopus 로고
    • Advanced glycation end products and bone loss during aging
    • Odetti P, Rossi S, Monacelli F, et al. Advanced glycation end products and bone loss during aging. Ann N Y Acad Sci 2005; 1043: 710-7.
    • (2005) Ann N Y Acad Sci , vol.1043 , pp. 710-717
    • Odetti, P.1    Rossi, S.2    Monacelli, F.3
  • 25
    • 76549123888 scopus 로고    scopus 로고
    • Collagen cross-links as a determinant of bone quality: A possible explanation for bone fragility in aging, osteoporosis, and diabetes mellitus
    • Saito M, Marumo K. Collagen cross-links as a determinant of bone quality: a possible explanation for bone fragility in aging, osteoporosis, and diabetes mellitus. Osteoporos Int 2010; 21: 195-214.
    • (2010) Osteoporos Int , vol.21 , pp. 195-214
    • Saito, M.1    Marumo, K.2
  • 26
    • 35548983431 scopus 로고    scopus 로고
    • Regulation of advanced glycation end product (AGE) receptors and apoptosis by AGEs in osteoblast-like cells
    • Mercer N, Ahmed H, Etcheverry SB, Vasta GR, Cortizo AM. Regulation of advanced glycation end product (AGE) receptors and apoptosis by AGEs in osteoblast-like cells. Mol Cell Biochem 2007; 306: 87-94.
    • (2007) Mol Cell Biochem , vol.306 , pp. 87-94
    • Mercer, N.1    Ahmed, H.2    Etcheverry, S.B.3    Vasta, G.R.4    Cortizo, A.M.5
  • 27
    • 46749116766 scopus 로고    scopus 로고
    • Metformin reverts deleterious effects of advanced glycation end-products (AGEs) on osteoblastic cells
    • Schurman L, McCarthy AD, Sedlinsky C, et al. Metformin reverts deleterious effects of advanced glycation end-products (AGEs) on osteoblastic cells. Exp Clin Endocrinol Diabetes 2008; 116: 333-40.
    • (2008) Exp Clin Endocrinol Diabetes , vol.116 , pp. 333-340
    • Schurman, L.1    McCarthy, A.D.2    Sedlinsky, C.3
  • 28
    • 0029997044 scopus 로고    scopus 로고
    • Role of nonenzymatic glycosylation of type I collagen in diabetic osteopenia
    • Katayama Y, Akatsu T, Yamamoto M, Kugai N, Nagata N. Role of nonenzymatic glycosylation of type I collagen in diabetic osteopenia. J Bone Miner Res 1996; 11: 931-7.
    • (1996) J Bone Miner Res , vol.11 , pp. 931-937
    • Katayama, Y.1    Akatsu, T.2    Yamamoto, M.3    Kugai, N.4    Nagata, N.5
  • 29
    • 0030765082 scopus 로고    scopus 로고
    • Nonenzymatic glycation of type I collagen modifies interaction with UMR 201-10B preosteoblastic cells
    • Katayama Y, Celic S, Nagata N, Martin TJ, Findlay DM. Nonenzymatic glycation of type I collagen modifies interaction with UMR 201-10B preosteoblastic cells. Bone 1997; 21: 237-42.
    • (1997) Bone , vol.21 , pp. 237-242
    • Katayama, Y.1    Celic, S.2    Nagata, N.3    Martin, T.J.4    Findlay, D.M.5
  • 30
    • 18744395526 scopus 로고    scopus 로고
    • Non-enzymatic glycosylation of a type I collagen matrix: Effects on osteoblastic development and oxidative stress
    • McCarthy AD, Etcheverry SB, Bruzzone L, et al. Non-enzymatic glycosylation of a type I collagen matrix: effects on osteoblastic development and oxidative stress. BMC Cell Biol 2001; 2: 16.
    • (2001) BMC Cell Biol , vol.2 , pp. 16
    • McCarthy, A.D.1    Etcheverry, S.B.2    Bruzzone, L.3
  • 31
    • 1542315275 scopus 로고    scopus 로고
    • Advanced glycation endproducts interefere with integrin-mediated osteoblastic attachment to a type-I collagen matrix
    • McCarthy AD, Uemura T, Etcheverry SB, Cortizo AM. Advanced glycation endproducts interefere with integrin-mediated osteoblastic attachment to a type-I collagen matrix. Int J Biochem Cell Biol 2004; 36: 840-8.
    • (2004) Int J Biochem Cell Biol , vol.36 , pp. 840-848
    • McCarthy, A.D.1    Uemura, T.2    Etcheverry, S.B.3    Cortizo, A.M.4
  • 32
    • 33846010477 scopus 로고    scopus 로고
    • Advanced glycation end products stimulate osteoblast apoptosis via the MAP kinase and cytosolic apoptotic pathways
    • Alikhani M, Alikhani Z, Boyd C, et al. Advanced glycation end products stimulate osteoblast apoptosis via the MAP kinase and cytosolic apoptotic pathways. Bone 2007; 40: 345-53.
    • (2007) Bone , vol.40 , pp. 345-353
    • Alikhani, M.1    Alikhani, Z.2    Boyd, C.3
  • 35
    • 0031065827 scopus 로고    scopus 로고
    • Advanced glycation end products enhance osteoclast-induced bone resorption in cultured mouse unfractionated bone cells and in rats implanted subcutaneously with devitalized bone particles
    • Miyata T, Notoya K, Yoshida K, et al. Advanced glycation end products enhance osteoclast-induced bone resorption in cultured mouse unfractionated bone cells and in rats implanted subcutaneously with devitalized bone particles. J Am Soc Nephrol 1997; 8: 260-70.
    • (1997) J Am Soc Nephrol , vol.8 , pp. 260-270
    • Miyata, T.1    Notoya, K.2    Yoshida, K.3
  • 36
    • 79958771169 scopus 로고    scopus 로고
    • In situ accumulation of advanced glycation endproducts (AGEs) in bone matrix and its correlation with osteoclastic bone resorption
    • (in press)
    • Dong XN, Qin A, Xu J, Wang X. In situ accumulation of advanced glycation endproducts (AGEs) in bone matrix and its correlation with osteoclastic bone resorption. Bone 2011 (in press)
    • (2011) Bone
    • Dong, X.N.1    Qin, A.2    Xu, J.3    Wang, X.4
  • 37
    • 34247094322 scopus 로고    scopus 로고
    • Non-enzymatic glycation of bone collagen modifies osteoclastic activity and differentiation
    • Valcourt U, Merle B, Gineyts E, et al. Non-enzymatic glycation of bone collagen modifies osteoclastic activity and differentiation. J Biol Chem 2007; 282: 5691-703.
    • (2007) J Biol Chem , vol.282 , pp. 5691-5703
    • Valcourt, U.1    Merle, B.2    Gineyts, E.3
  • 38
    • 33645880137 scopus 로고    scopus 로고
    • Regulation of osteoclast function and bone mass by RAGE
    • Zhou Z, Immel D, Xi CX, et al. Regulation of osteoclast function and bone mass by RAGE. J Exp Med 2006; 203: 1067-80.
    • (2006) J Exp Med , vol.203 , pp. 1067-1080
    • Zhou, Z.1    Immel, D.2    Xi, C.X.3
  • 39
    • 30544447043 scopus 로고    scopus 로고
    • Disordered osteoclast formation in RAGE-deficient mouse establishes an essential role for RAGE in diabetes related bone loss
    • Ding KH, Wang ZZ, Hamrick MW, et al. Disordered osteoclast formation in RAGE-deficient mouse establishes an essential role for RAGE in diabetes related bone loss. Biochem Biophys Res Commun 2006; 340: 1091-7.
    • (2006) Biochem Biophys Res Commun , vol.340 , pp. 1091-1097
    • Ding, K.H.1    Wang, Z.Z.2    Hamrick, M.W.3
  • 40
    • 35148861052 scopus 로고    scopus 로고
    • Advanced glycation endproducts influence the mRNA expression of RAGE, RANKL and various osteoblastic genes in human osteoblasts
    • Franke S, Siggelkow H, Wolf G, Hein G. Advanced glycation endproducts influence the mRNA expression of RAGE, RANKL and various osteoblastic genes in human osteoblasts. Arch Physiol Biochem 2007; 113: 154-61.
    • (2007) Arch Physiol Biochem , vol.113 , pp. 154-161
    • Franke, S.1    Siggelkow, H.2    Wolf, G.3    Hein, G.4
  • 42
    • 46249112770 scopus 로고    scopus 로고
    • HMGB1 regulates RANKL-induced osteoclastogenesis in a manner dependent on RAGE
    • Zhou Z, Han JY, Xi CX, et al. HMGB1 regulates RANKL-induced osteoclastogenesis in a manner dependent on RAGE. J Bone Miner Res 2008; 23: 1084-96.
    • (2008) J Bone Miner Res , vol.23 , pp. 1084-1096
    • Zhou, Z.1    Han, J.Y.2    Xi, C.X.3
  • 43
    • 77958026890 scopus 로고    scopus 로고
    • Advanced glycation end products induce chemokine/cytokine production via activation of p38 pathway and inhibit proliferation and migration of bone marrow mesenchymal stem cells
    • Yang K, Wang XQ, He YS, et al. Advanced glycation end products induce chemokine/cytokine production via activation of p38 pathway and inhibit proliferation and migration of bone marrow mesenchymal stem cells. Cardiovasc Diabetol 2010; 9: 66.
    • (2010) Cardiovasc Diabetol , vol.9 , pp. 66
    • Yang, K.1    Wang, X.Q.2    He, Y.S.3
  • 45
    • 24144449526 scopus 로고    scopus 로고
    • Advanced glycation endproducts attenuate human mesenchymal stem cells and prevent cognate differentiation into adipose tissue, cartilage, and bone
    • Kume S, Kato S, Yamagishi S, et al. Advanced glycation endproducts attenuate human mesenchymal stem cells and prevent cognate differentiation into adipose tissue, cartilage, and bone. J Bone Miner Res 2005; 20: 1647-58.
    • (2005) J Bone Miner Res , vol.20 , pp. 1647-1658
    • Kume, S.1    Kato, S.2    Yamagishi, S.3
  • 46
    • 72049112298 scopus 로고    scopus 로고
    • Non-enzymatic glycation alters microdamage formation in human cancellous bone
    • Tang SY, Vashishth D. Non-enzymatic glycation alters microdamage formation in human cancellous bone. Bone 2010; 46: 148-54.
    • (2010) Bone , vol.46 , pp. 148-154
    • Tang, S.Y.1    Vashishth, D.2
  • 47
    • 33748645515 scopus 로고    scopus 로고
    • Role of collagen enzymatic and glycation induced cross-links as a determinant of bone quality in spontaneously diabetic WBN/Kob rats
    • Saito M, Fujii K, Mori Y, Marumo K. Role of collagen enzymatic and glycation induced cross-links as a determinant of bone quality in spontaneously diabetic WBN/Kob rats. Osteoporos Int 2006; 17: 1514-23.
    • (2006) Osteoporos Int , vol.17 , pp. 1514-1523
    • Saito, M.1    Fujii, K.2    Mori, Y.3    Marumo, K.4
  • 48
    • 78650976038 scopus 로고    scopus 로고
    • The relative contributions of non-enzymatic glycation and cortical porosity on the fracture toughness of aging bone
    • Tang SY, Vashishth D. The relative contributions of non-enzymatic glycation and cortical porosity on the fracture toughness of aging bone. J Biomech 2011; 44: 330-6.
    • (2011) J Biomech , vol.44 , pp. 330-336
    • Tang, S.Y.1    Vashishth, D.2
  • 49
    • 33749518488 scopus 로고    scopus 로고
    • Contribution of the advanced glycation end product pentosidine and of maturation of type I collagen to compressive biomechanical properties of human lumbar vertebrae
    • Viguet-Carrin S, Roux JP, Arlot ME, et al. Contribution of the advanced glycation end product pentosidine and of maturation of type I collagen to compressive biomechanical properties of human lumbar vertebrae. Bone 2006; 39: 1073-9.
    • (2006) Bone , vol.39 , pp. 1073-1079
    • Viguet-Carrin, S.1    Roux, J.P.2    Arlot, M.E.3
  • 50
    • 29144482502 scopus 로고    scopus 로고
    • Advanced glycation end product modification of bone proteins and bone remodelling: Hypothesis and preliminary immunohistochemical findings
    • Hein G, Weiss C, Lehmann G, et al. Advanced glycation end product modification of bone proteins and bone remodelling: hypothesis and preliminary immunohistochemical findings. Ann Rheum Dis 2006; 65: 101-4.
    • (2006) Ann Rheum Dis , vol.65 , pp. 101-104
    • Hein, G.1    Weiss, C.2    Lehmann, G.3
  • 51
    • 40849130165 scopus 로고    scopus 로고
    • Serum pentosidine levels are positively associated with the presence of vertebral fractures in postmenopausal women with type 2 diabetes
    • Yamamoto M, Yamaguchi T, Yamauchi M, Yano S, Sugimoto T. Serum pentosidine levels are positively associated with the presence of vertebral fractures in postmenopausal women with type 2 diabetes. J Clin Endocrinol Metab 2008; 93: 1013-9.
    • (2008) J Clin Endocrinol Metab , vol.93 , pp. 1013-1019
    • Yamamoto, M.1    Yamaguchi, T.2    Yamauchi, M.3    Yano, S.4    Sugimoto, T.5
  • 52
    • 0141997270 scopus 로고    scopus 로고
    • Advanced glycation end-products pentosidine and N epsiloncarboxymethyllysine are elevated in serum of patients with osteoporosis
    • Hein G, Wiegand R, Lehmann G, Stein G, Franke S. Advanced glycation end-products pentosidine and N epsiloncarboxymethyllysine are elevated in serum of patients with osteoporosis. Rheumatology (Oxford) 2003; 42: 1242-6.
    • (2003) Rheumatology (Oxford) , vol.42 , pp. 1242-1246
    • Hein, G.1    Wiegand, R.2    Lehmann, G.3    Stein, G.4    Franke, S.5
  • 53
    • 37349091942 scopus 로고    scopus 로고
    • Nonenzymatic collagen cross-links induced by glycoxidation (pentosidine) predicts vertebral fractures
    • Shiraki M, Kuroda T, Tanaka S, Saito M, Fukunaga M, Nakamura T. Nonenzymatic collagen cross-links induced by glycoxidation (pentosidine) predicts vertebral fractures. J Bone Miner Metab 2008; 26: 93-100.
    • (2008) J Bone Miner Metab , vol.26 , pp. 93-100
    • Shiraki, M.1    Kuroda, T.2    Tanaka, S.3    Saito, M.4    Fukunaga, M.5    Nakamura, T.6
  • 54
    • 79951680329 scopus 로고    scopus 로고
    • Urinary pentosidine and plasma homocysteine levels at baseline predict future fractures in osteoporosis patients under bisphosphonate treatment
    • Shiraki M, Kuroda T, Shiraki Y, Tanaka S, Higuchi T, Saito M. Urinary pentosidine and plasma homocysteine levels at baseline predict future fractures in osteoporosis patients under bisphosphonate treatment. J Bone Miner Metab 2011; 29: 62-70.
    • (2011) J Bone Miner Metab , vol.29 , pp. 62-70
    • Shiraki, M.1    Kuroda, T.2    Shiraki, Y.3    Tanaka, S.4    Higuchi, T.5    Saito, M.6
  • 55
    • 67650263891 scopus 로고    scopus 로고
    • Pentosidine and increased fracture risk in older adults with type 2 diabetes
    • Schwartz AV, Garnero P, Hillier TA, et al. Pentosidine and increased fracture risk in older adults with type 2 diabetes. J Clin Endocrinol Metab 2009; 94: 2380-6.
    • (2009) J Clin Endocrinol Metab , vol.94 , pp. 2380-2386
    • Schwartz, A.V.1    Garnero, P.2    Hillier, T.A.3
  • 56
    • 72249109142 scopus 로고    scopus 로고
    • Low serum level of the endogenous secretory receptor for advanced glycation end products (esRAGE) is a risk factor for prevalent vertebral fractures independent of bone mineral density in patients with type 2 diabetes
    • Yamamoto M, Yamaguchi T, Yamauchi M, Sugimoto T. Low serum level of the endogenous secretory receptor for advanced glycation end products (esRAGE) is a risk factor for prevalent vertebral fractures independent of bone mineral density in patients with type 2 diabetes. Diabetes Care 2009; 32: 2263-8.
    • (2009) Diabetes Care , vol.32 , pp. 2263-2268
    • Yamamoto, M.1    Yamaguchi, T.2    Yamauchi, M.3    Sugimoto, T.4
  • 57
    • 35348927441 scopus 로고    scopus 로고
    • Kinetics, role and therapeutic implications of endogenous soluble form of receptor for advanced glycation end products (sRAGE) in diabetes
    • Yamagishi S, Matsui T, Nakamura K. Kinetics, role and therapeutic implications of endogenous soluble form of receptor for advanced glycation end products (sRAGE) in diabetes. Curr Drug Targets 2007; 8: 1138-43.
    • (2007) Curr Drug Targets , vol.8 , pp. 1138-1143
    • Yamagishi, S.1    Matsui, T.2    Nakamura, K.3
  • 58
    • 54049108485 scopus 로고    scopus 로고
    • A soluble form of the receptor for advanced glycation endproducts (RAGE) is produced by proteolytic cleavage of the membrane-bound form by the sheddase a disintegrin and metalloprotease 10 (ADAM10)
    • Raucci A, Cugusi S, Antonelli A, et al. A soluble form of the receptor for advanced glycation endproducts (RAGE) is produced by proteolytic cleavage of the membrane-bound form by the sheddase a disintegrin and metalloprotease 10 (ADAM10). FASEB J 2008; 22: 3716-27.
    • (2008) FASEB J , vol.22 , pp. 3716-3727
    • Raucci, A.1    Cugusi, S.2    Antonelli, A.3
  • 59
    • 0031717894 scopus 로고    scopus 로고
    • Suppression of accelerated diabetic atherosclerosis by the soluble receptor for advanced glycation endproducts
    • Park L, Raman KG, Lee KJ, et al. Suppression of accelerated diabetic atherosclerosis by the soluble receptor for advanced glycation endproducts. Nat Med 1998; 4: 1025-31.
    • (1998) Nat Med , vol.4 , pp. 1025-1031
    • Park, L.1    Raman, K.G.2    Lee, K.J.3
  • 60
    • 0037180531 scopus 로고    scopus 로고
    • Schmidt: RAGE blockade stabilizes established atherosclerosis in diabetic apolipoprotein Enull mice
    • Bucciarelli LG, Wendt T, Qu W, et al. Schmidt: RAGE blockade stabilizes established atherosclerosis in diabetic apolipoprotein Enull mice. Circulation 2002; 106: 2827-35.
    • (2002) Circulation , vol.106 , pp. 2827-2835
    • Bucciarelli, L.G.1    Wendt, T.2    Qu, W.3
  • 61
    • 33947386181 scopus 로고    scopus 로고
    • Soluble RAGE but not endogenous secretory RAGE is associated with albuminuria in patients with type 2 diabetes
    • Humpert PM, Djuric Z, Kopf S, et al. Soluble RAGE but not endogenous secretory RAGE is associated with albuminuria in patients with type 2 diabetes. Cardiovasc Diabetol 2007; 6: 9.
    • (2007) Cardiovasc Diabetol , vol.6 , pp. 9
    • Humpert, P.M.1    Djuric, Z.2    Kopf, S.3
  • 62
    • 71849085213 scopus 로고    scopus 로고
    • Factors associated with serum high mobility group box 1 (HMGB1) levels in a general population
    • Fukami A, Adachi H, Yamagishi S, et al. Factors associated with serum high mobility group box 1 (HMGB1) levels in a general population. Metabolism 2009; 58: 1688-93.
    • (2009) Metabolism , vol.58 , pp. 1688-1693
    • Fukami, A.1    Adachi, H.2    Yamagishi, S.3
  • 63
    • 52749084063 scopus 로고    scopus 로고
    • Receptor for advanced glycation end products (RAGE) deficiency attenuates the development of atherosclerosis in diabetes
    • Soro-Paavonen A, Watson AM, Li J, et al. Receptor for advanced glycation end products (RAGE) deficiency attenuates the development of atherosclerosis in diabetes. Diabetes 2008; 57: 2461-9.
    • (2008) Diabetes , vol.57 , pp. 2461-2469
    • Soro-Paavonen, A.1    Watson, A.M.2    Li, J.3
  • 64
    • 0033162931 scopus 로고    scopus 로고
    • Developments in the therapeutic applications of bisphosphonates
    • Brown DL, Robbins R. Developments in the therapeutic applications of bisphosphonates. J Clin Pharmacol 1999; 39: 651-60.
    • (1999) J Clin Pharmacol , vol.39 , pp. 651-660
    • Brown, D.L.1    Robbins, R.2
  • 65
    • 0033554651 scopus 로고    scopus 로고
    • Farnesyl pyrophosphate synthase is the molecular target of nitrogen-containing bisphosphonates
    • Van Beek E, Pieterman E, Cohen L, Lowik C, Papapoulos S. Farnesyl pyrophosphate synthase is the molecular target of nitrogen-containing bisphosphonates. Biochem Biophys Res Commun 1999; 264: 108-111.
    • (1999) Biochem Biophys Res Commun , vol.264 , pp. 108-111
    • van Beek, E.1    Pieterman, E.2    Cohen, L.3    Lowik, C.4    Papapoulos, S.5
  • 66
    • 9644262751 scopus 로고    scopus 로고
    • Minodronate, a newly developed nitrogen-containing bisphosphonate, suppresses melanoma growth and improves survival in nude mice by blocking vascular endothelial growth factor signaling
    • Yamagishi S, Abe R, Inagaki Y, Minodronate, a newly developed nitrogen-containing bisphosphonate, suppresses melanoma growth and improves survival in nude mice by blocking vascular endothelial growth factor signaling. Am J Pathol 2004; 165: 1865-74.
    • (2004) Am J Pathol , vol.165 , pp. 1865-1874
    • Yamagishi, S.1    Abe, R.2    Inagaki, Y.3
  • 67
    • 0036884617 scopus 로고    scopus 로고
    • Angiogenesis induced by advanced glycation end products and its prevention by cerivastatin
    • Okamoto T, Yamagishi S, Inagaki Y, et al. Angiogenesis induced by advanced glycation end products and its prevention by cerivastatin. FASEB J 2002; 16: 1928-30.
    • (2002) FASEB J , vol.16 , pp. 1928-1930
    • Okamoto, T.1    Yamagishi, S.2    Inagaki, Y.3
  • 68
    • 0036399062 scopus 로고    scopus 로고
    • Incadronate disodium inhibits advanced glycation end products-induced angiogenesis in vitro
    • Okamoto T, Yamagishi S, Inagaki Y, et al. Incadronate disodium inhibits advanced glycation end products-induced angiogenesis in vitro. Biochem Biophys Res Commun 2002; 297: 419-24.
    • (2002) Biochem Biophys Res Commun , vol.297 , pp. 419-424
    • Okamoto, T.1    Yamagishi, S.2    Inagaki, Y.3
  • 69
    • 30344434002 scopus 로고    scopus 로고
    • Minodronate, a nitrogen-containing bisphosphonate, inhibits advanced glycation end product-induced vascular cell adhesion molecule-1 expression in endothelial cells by suppressing reactive oxygen species generation
    • Yamagishi S, Matsui T, Nakamura K, Takeuchi M. Minodronate, a nitrogen-containing bisphosphonate, inhibits advanced glycation end product-induced vascular cell adhesion molecule-1 expression in endothelial cells by suppressing reactive oxygen species generation. Int J Tissue React 2005; 27: 189-95.
    • (2005) Int J Tissue React , vol.27 , pp. 189-195
    • Yamagishi, S.1    Matsui, T.2    Nakamura, K.3    Takeuchi, M.4
  • 70
    • 55949126330 scopus 로고    scopus 로고
    • Opposing effects of bisphosphonates and advanced glycation endproducts on osteoblastic cells
    • Gangoiti MV, Cortizo AM, Arnol V, Felice JI, McCarthy AD. Opposing effects of bisphosphonates and advanced glycation endproducts on osteoblastic cells. Eur J Pharmacol 2008; 600: 140-7.
    • (2008) Eur J Pharmacol , vol.600 , pp. 140-147
    • Gangoiti, M.V.1    Cortizo, A.M.2    Arnol, V.3    Felice, J.I.4    McCarthy, A.D.5
  • 71
    • 67349105623 scopus 로고    scopus 로고
    • Changes in non-enzymatic glycation and its association with altered mechanical properties following 1-year treatment with risedronate or alendronate
    • Tang SY, Allen MR, Phipps R, Burr DB, Vashishth D. Changes in non-enzymatic glycation and its association with altered mechanical properties following 1-year treatment with risedronate or alendronate. Osteoporos Int 2009; 20: 887-94.
    • (2009) Osteoporos Int , vol.20 , pp. 887-894
    • Tang, S.Y.1    Allen, M.R.2    Phipps, R.3    Burr, D.B.4    Vashishth, D.5
  • 72
    • 49549114063 scopus 로고    scopus 로고
    • Collagen maturity, glycation induced-pentosidine, and mineralization are increased following 3-year treatment with incadronate in dogs
    • Saito M, Mori S, Mashiba T, Komatsubara S, Marumo K. Collagen maturity, glycation induced-pentosidine, and mineralization are increased following 3-year treatment with incadronate in dogs. Osteoporos Int 2008; 19: 1343-54.
    • (2008) Osteoporos Int , vol.19 , pp. 1343-1354
    • Saito, M.1    Mori, S.2    Mashiba, T.3    Komatsubara, S.4    Marumo, K.5
  • 73
    • 78349249359 scopus 로고    scopus 로고
    • Atypical subtrochanteric and diaphyseal femoral fractures: Report of a task force of the American Society for Bone and Mineral Research
    • Shane E, Burr D, Ebeling PR, et al. Atypical subtrochanteric and diaphyseal femoral fractures: report of a task force of the American Society for Bone and Mineral Research. J Bone Miner Res 2010; 25: 2267-94.
    • (2010) J Bone Miner Res , vol.25 , pp. 2267-2294
    • Shane, E.1    Burr, D.2    Ebeling, P.R.3
  • 74
    • 77955961158 scopus 로고    scopus 로고
    • New selective estrogen receptor modulators (SERMs) in development
    • Silverman SL. New selective estrogen receptor modulators (SERMs) in development. Curr Osteoporos Rep 2010; 8: 151-3.
    • (2010) Curr Osteoporos Rep , vol.8 , pp. 151-153
    • Silverman, S.L.1
  • 75
    • 77950921735 scopus 로고    scopus 로고
    • Raloxifene ameliorates detrimental enzymatic and nonenzymatic collagen cross-links and bone strength in rabbits with hyperhomocysteinemia
    • Saito M, Marumo K, Soshi S, Kida Y, Ushiku C, Shinohara A. Raloxifene ameliorates detrimental enzymatic and nonenzymatic collagen cross-links and bone strength in rabbits with hyperhomocysteinemia. Osteoporos Int 2010; 21: 655-66.
    • (2010) Osteoporos Int , vol.21 , pp. 655-666
    • Saito, M.1    Marumo, K.2    Soshi, S.3    Kida, Y.4    Ushiku, C.5    Shinohara, A.6
  • 76
    • 67650081125 scopus 로고    scopus 로고
    • The decrease of soluble RAGE levels in rheumatoid arthritis patients following hormone replacement therapy is associated with increased bone mineral density and diminished bone/cartilage turnover: A randomized controlled trial
    • Pullerits R, d'Elia HF, Tarkowski A, Carlsten H. The decrease of soluble RAGE levels in rheumatoid arthritis patients following hormone replacement therapy is associated with increased bone mineral density and diminished bone/cartilage turnover: a randomized controlled trial. Rheumatology (Oxford) 2009; 48: 785-90.
    • (2009) Rheumatology (Oxford) , vol.48 , pp. 785-790
    • Pullerits, R.1    D'Elia, H.F.2    Tarkowski, A.3    Carlsten, H.4
  • 77
    • 0036787371 scopus 로고    scopus 로고
    • Low parathyroid hormone and pentosidine in hemodialysis patients
    • Panuccio V, Mallamaci F, Tripepi G, et al. Low parathyroid hormone and pentosidine in hemodialysis patients. Am J Kidney Dis 2002; 40: 810-5.
    • (2002) Am J Kidney Dis , vol.40 , pp. 810-815
    • Panuccio, V.1    Mallamaci, F.2    Tripepi, G.3
  • 78
    • 79960276545 scopus 로고    scopus 로고
    • Changes in the contents of enzymatic immature, mature, and non-enzymatic senescent crosslinks of collagen after once-weekly treatment with human parathyroid hormone (1-34) for 18 months contribute to improvement of bone strength in ovariectomized monkeys
    • (in press)
    • Saito M, Marumo K, Kida Y, et al. Changes in the contents of enzymatic immature, mature, and non-enzymatic senescent crosslinks of collagen after once-weekly treatment with human parathyroid hormone (1-34) for 18 months contribute to improvement of bone strength in ovariectomized monkeys. Osteoporos Int 2011 (in press).
    • (2011) Osteoporos Int
    • Saito, M.1    Marumo, K.2    Kida, Y.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.