Inhibition of the mitochondrial enzyme ABAD restores the amyloid-β-mediated deregulation of estradiol

PLoS ONE

Volumn 6, Issue 12, 2011, Pages

  Lim, Yun An ^a   Grimm, Amandine ^b   Giese, Maria ^b   Mensah Nyagan, Ayikoe Guy ^c   Villafranca, J Ernest ^d   Ittner, Lars M ^a   Eckert, Anne ^b   Götz, Jürgen ^a  

^a UNIVERSITY OF SYDNEY   (Australia)

^b UNIVERSITY OF BASEL   (Switzerland)

^c UNIVERSITÉ DE STRASBOURG   (France)

^d Villafranca Consulting   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AG 18051; AMYLIN; AMYLOID BETA BINDING ALCOHOL DEHYDROGENASE; AMYLOID BETA PROTEIN[1-42]; ENZYME INHIBITOR; ESTRADIOL; LACTATE DEHYDROGENASE; MITOCHONDRIAL ENZYME; REACTIVE OXYGEN METABOLITE; TETRAZOLIUM; UNCLASSIFIED DRUG; 3 HYDROXYACYL COENZYME A DEHYDROGENASE; AMYLOID BETA PROTEIN; AMYLOID BETA PROTEIN (1 42); AMYLOID BETA-PROTEIN (1-42); HSD17B10 PROTEIN, HUMAN; PEPTIDE FRAGMENT;

ALZHEIMER DISEASE; ARTICLE; CONTROLLED STUDY; DISORDERS OF MITOCHONDRIAL FUNCTIONS; DOWN REGULATION; DRUG MECHANISM; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME RELEASE; HUMAN; HUMAN CELL; MITOCHONDRIAL RESPIRATION; NEUROBLASTOMA CELL; NEUROTOXICITY; NON INSULIN DEPENDENT DIABETES MELLITUS; OXIDATIVE STRESS; PATHOGENESIS; PROTEIN AGGREGATION; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; REGULATORY MECHANISM; CELL LINE; CELL PROTECTION; CELL RESPIRATION; CELL SURVIVAL; CHEMISTRY; DRUG EFFECT; ENZYMOLOGY; METABOLISM; MITOCHONDRION; OXIDATIVE PHOSPHORYLATION; OXYGEN CONSUMPTION; PROTEIN BINDING;

3-HYDROXYACYL COA DEHYDROGENASES; AMYLOID BETA-PEPTIDES; CELL LINE; CELL RESPIRATION; CELL SURVIVAL; CYTOPROTECTION; DOWN-REGULATION; ENZYME INHIBITORS; ESTRADIOL; HUMANS; ISLET AMYLOID POLYPEPTIDE; MITOCHONDRIA; OXIDATIVE PHOSPHORYLATION; OXYGEN CONSUMPTION; PEPTIDE FRAGMENTS; PROTEIN BINDING; REACTIVE OXYGEN SPECIES;

EID: 83155183308     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0028887     Document Type: Article

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