-
1
-
-
84868269034
-
Dementia prevalence
-
OECD, OECD
-
OECD, Dementia prevalence. OECD, Health at a Glance: Europe 2010 2010 OECD 54 55
-
(2010)
OECD, Health at a Glance: Europe 2010
, vol.54
, pp. 55
-
-
-
2
-
-
20444504698
-
The genetic epidemiology of neurodegenerative disease
-
DOI 10.1172/JCI24761
-
Bertram L., Tanzi R. E., The genetic epidemiology of neurodegenerative disease. The Journal of Clinical Investigation 2005 115 6 1449 1457 2-s2.0-20444504698 10.1172/JCI24761 (Pubitemid 40814649)
-
(2005)
Journal of Clinical Investigation
, vol.115
, Issue.6
, pp. 1449-1457
-
-
Bertram, L.1
Tanzi, R.E.2
-
3
-
-
29144508843
-
Global prevalence of dementia: A Delphi consensus study
-
DOI 10.1016/S0140-6736(05)67889-0, PII S0140673605678890
-
Ferri C. P., Prince M., Brayne C., Brodaty H., Fratiglioni L., Ganguli M., Hall K., Hasegawa K., Hendrie H., Huang Y., Jorm A., Mathers C., Menezes P. R., Rimmer E., Scazufca M., Global prevalence of dementia: a Delphi consensus study. The Lancet 2005 366 9503 2112 2117 2-s2.0-29144508843 10.1016/S0140-6736(05)67889-0 (Pubitemid 41797645)
-
(2005)
Lancet
, vol.366
, Issue.9503
, pp. 2112-2117
-
-
Ferri, C.P.1
Prince, M.2
Brayne, C.3
Brodaty, H.4
Fratiglioni, L.5
Ganguli, M.6
Hall, K.7
Hasegawa, K.8
Hendrie, H.9
Huang, Y.10
Jorm, A.11
Mathers, C.12
Menezes, P.R.13
Rimmer, E.14
Scazufca, M.15
-
4
-
-
84868275776
-
-
American Health Assistance Foundation. Alzheimer disease research: about Alzheimer
-
American Health Assistance Foundation. Alzheimer disease research: about Alzheimer
-
-
-
-
5
-
-
78650413213
-
Diagnosis and biomarkers of predementia in Alzheimer's disease
-
2-s2.0-78650413213 10.1186/1741-7015-8-89
-
Forlenza O. V., Diniz B. S., Gattaz W. F., Diagnosis and biomarkers of predementia in Alzheimer's disease. BMC Medicine 2010 8, article 89 2-s2.0-78650413213 10.1186/1741-7015-8-89
-
(2010)
BMC Medicine
, vol.889
-
-
Forlenza, O.V.1
Diniz, B.S.2
Gattaz, W.F.3
-
7
-
-
54249137157
-
Oligomeric and fibrillar species of β -amyloid (A β 42) both impair mitochondrial function in P301L tau transgenic mice
-
2-s2.0-54249137157 10.1007/s00109-008-0391-6
-
Eckert A., Hauptmann S., Scherping I., Meinhardt J., Rhein V., Dröse S., Brandt U., Fändrich M., Müller W. E., Götz J., Oligomeric and fibrillar species of β -amyloid (A β 42) both impair mitochondrial function in P301L tau transgenic mice. Journal of Molecular Medicine 2008 86 11 1255 1267 2-s2.0-54249137157 10.1007/s00109-008-0391-6
-
(2008)
Journal of Molecular Medicine
, vol.86
, Issue.11
, pp. 1255-1267
-
-
Eckert, A.1
Hauptmann, S.2
Scherping, I.3
Meinhardt, J.4
Rhein, V.5
Dröse, S.6
Brandt, U.7
Fändrich, M.8
Müller, W.E.9
Götz, J.10
-
8
-
-
69249211284
-
Mitochondrial dysfunction: An early event in Alzheimer pathology accumulates with age in AD transgenic mice
-
2-s2.0-69249211284 10.1016/j.neurobiolaging.2007.12.005
-
Hauptmann S., Scherping I., Dröse S., Brandt U., Schulz K. L., Jendrach M., Leuner K., Eckert A., Müller W. E., Mitochondrial dysfunction: an early event in Alzheimer pathology accumulates with age in AD transgenic mice. Neurobiology of Aging 2009 30 10 1574 1586 2-s2.0-69249211284 10.1016/j.neurobiolaging.2007.12.005
-
(2009)
Neurobiology of Aging
, vol.30
, Issue.10
, pp. 1574-1586
-
-
Hauptmann, S.1
Scherping, I.2
Dröse, S.3
Brandt, U.4
Schulz, K.L.5
Jendrach, M.6
Leuner, K.7
Eckert, A.8
Müller, W.E.9
-
9
-
-
11144353586
-
ABAD Directly Links Aβ to Mitochondrial Toxicity in Alzheimer's Disease
-
DOI 10.1126/science.1091230
-
Lustbader J. W., Cirilli M., Lin C., Xu H. W., Takuma K., Wang N., Caspersen C., Chen X., Pollak S., Chaney M., Trinchese F., Liu S., Gunn-Moore F., Lue L. F., Walker D. G., Kappasamy P., Zewier Z. L., Arancio O., Stern D., Yan S. S., Wu H., ABAD directly links A β to mitochondrial toxicity in Alzheimer's disease. Science 2004 304 5669 448 452 2-s2.0-11144353586 10.1126/science.1091230 (Pubitemid 38495942)
-
(2004)
Science
, vol.304
, Issue.5669
, pp. 448-452
-
-
Lustbader, J.W.1
Cirilli, M.2
Lin, C.3
Xu, H.W.4
Takuma, K.5
Wang, N.6
Caspersen, C.7
Chen, X.8
Pollak, S.9
Chaney, M.10
Trinchese, F.11
Liu, S.12
Gunn-Moore, F.13
Lue, L.-F.14
Walker, D.G.15
Kappasamy, P.16
Zewier, Z.L.17
Arancio, O.18
Stern, D.19
Yan, S.S.D.20
Wu, H.21
more..
-
10
-
-
77957326921
-
Oxidative stress and its implications for future treatments and management of alzheimer disease
-
2-s2.0-77957326921
-
Clark T. A., Lee H. P., Rolston R. K., Zhu X., Marlatt M. W., Castellani R. J., Nunomura A., Casadesus G., Smith M. A., Lee H. G., Perry G., Oxidative stress and its implications for future treatments and management of alzheimer disease. International Journal of Biomedical Science 2010 6 3 225 227 2-s2.0-77957326921
-
(2010)
International Journal of Biomedical Science
, vol.6
, Issue.3
, pp. 225-227
-
-
Clark, T.A.1
Lee, H.P.2
Rolston, R.K.3
Zhu, X.4
Marlatt, M.W.5
Castellani, R.J.6
Nunomura, A.7
Casadesus, G.8
Smith, M.A.9
Lee, H.G.10
Perry, G.11
-
11
-
-
58049218922
-
Amyloid- β overproduction causes abnormal mitochondrial dynamics via differential modulation of mitochondrial fission/fusion proteins
-
2-s2.0-58049218922 10.1073/pnas.0804871105
-
Wang X., Su B., Siedlak S. L., Moreira P. I., Fujioka H., Wang Y., Casadesus G., Zhu X., Amyloid- β overproduction causes abnormal mitochondrial dynamics via differential modulation of mitochondrial fission/fusion proteins. Proceedings of the National Academy of Sciences of the United States of America 2008 105 49 19318 19323 2-s2.0-58049218922 10.1073/pnas.0804871105
-
(2008)
Proceedings of the National Academy of Sciences of the United States of America
, vol.105
, Issue.49
, pp. 19318-19323
-
-
Wang, X.1
Su, B.2
Siedlak, S.L.3
Moreira, P.I.4
Fujioka, H.5
Wang, Y.6
Casadesus, G.7
Zhu, X.8
-
12
-
-
0035741979
-
The Swedish APP670/671 Alzheimer's disease mutation: The first evidence for strikingly increased oxidative injury in the temporal inferior cortex
-
DOI 10.1159/000051282
-
Bogdanovic N., Zilmer M., Zilmer K., Rehema A., Karelson E., The Swedish APP670/671 Alzheimer's disease mutation: the first evidence for strikingly increased oxidative injury in the temporal inferior cortex. Dementia and Geriatric Cognitive Disorders 2001 12 6 364 370 2-s2.0-0035741979 10.1159/000051282 (Pubitemid 34701659)
-
(2001)
Dementia and Geriatric Cognitive Disorders
, vol.12
, Issue.6
, pp. 364-370
-
-
Bogdanovic, N.1
Zilmer, M.2
Zilmer, K.3
Rehema, A.4
Karelson, E.5
-
13
-
-
0035875690
-
Increased lipid peroxidation precedes amyloid plaque formation in an animal model of alzheimer amyloidosis
-
Praticò D., Uryu K., Leight S., Trojanoswki J. Q., Lee V. M. Y., Increased lipid peroxidation precedes amyloid plaque formation in an animal model of alzheimer amyloidosis. Journal of Neuroscience 2001 21 12 4183 4187 2-s2.0-0035875690 (Pubitemid 32538543)
-
(2001)
Journal of Neuroscience
, vol.21
, Issue.12
, pp. 4183-4187
-
-
Pratico, D.1
Uryu, K.2
Leight, S.3
Trojanoswki, J.Q.4
Lee, V.M.-Y.5
-
14
-
-
79751507068
-
PLA2G3, a gene involved in oxidative stress induced death, is associated with Alzheimer's disease
-
mjbullido@cbm.uam.es 10.3233/JAD-2010-101348
-
Martínez-García A., Sastre I., Recuero M., Aldudo J., Vilella E., Mateo I., Sánchez-Juan P., Vargas T., Carro E., Bermejo-Pareja F., Rodríguez-Rodríguez E., Combarros O., Rosich-Estrago M., Frank A., Valdivieso F., Bullido M. J., mjbullido@cbm.uam.es PLA2G3, a gene involved in oxidative stress induced death, is associated with Alzheimer's disease. Journal of Alzheimer's Disease 2010 22 4 1181 1187 10.3233/JAD-2010-101348
-
(2010)
Journal of Alzheimer's Disease
, vol.22
, Issue.4
, pp. 1181-1187
-
-
Martínez-García, A.1
Sastre, I.2
Recuero, M.3
Aldudo, J.4
Vilella, E.5
Mateo, I.6
Sánchez-Juan, P.7
Vargas, T.8
Carro, E.9
Bermejo-Pareja, F.10
Rodríguez-Rodríguez, E.11
Combarros, O.12
Rosich-Estrago, M.13
Frank, A.14
Valdivieso, F.15
Bullido, M.J.16
-
15
-
-
77954957989
-
A β accumulation in choroid plexus is associated with mitochondrial-induced apoptosis
-
2-s2.0-77954957989 10.1016/j.neurobiolaging.2008.08.017
-
Vargas T., Ugalde C., Spuch C., Antequera D., Morán M. J., Martín M. A., Ferrer I., Bermejo-Pareja F., Carro E., A β accumulation in choroid plexus is associated with mitochondrial-induced apoptosis. Neurobiology of Aging 2010 31 9 1569 1581 2-s2.0-77954957989 10.1016/j.neurobiolaging.2008.08.017
-
(2010)
Neurobiology of Aging
, vol.31
, Issue.9
, pp. 1569-1581
-
-
Vargas, T.1
Ugalde, C.2
Spuch, C.3
Antequera, D.4
Morán, M.J.5
Martín, M.A.6
Ferrer, I.7
Bermejo-Pareja, F.8
Carro, E.9
-
16
-
-
69949118812
-
Oxidative stress damage and oxidative stress responses in the choroid plexus in Alzheimer's disease
-
2-s2.0-69949118812 10.1007/s00401-009-0574-4
-
Perez-Gracia E., Blanco R., Carmona M., Carro E., Ferrer I., Oxidative stress damage and oxidative stress responses in the choroid plexus in Alzheimer's disease. Acta Neuropathologica 2009 118 4 497 504 2-s2.0-69949118812 10.1007/s00401-009-0574-4
-
(2009)
Acta Neuropathologica
, vol.118
, Issue.4
, pp. 497-504
-
-
Perez-Gracia, E.1
Blanco, R.2
Carmona, M.3
Carro, E.4
Ferrer, I.5
-
17
-
-
0034235229
-
The internal structure of mitochondria
-
DOI 10.1016/S0968-0004(00)01609-1, PII S0968000400016091
-
Freya T. G., Mannellab C. A., The internal structure of mitochondria. Trends in Biochemical Sciences 2000 25 7 319 324 2-s2.0-0034235229 10.1016/S0968-0004(00)01609-1 (Pubitemid 30421097)
-
(2000)
Trends in Biochemical Sciences
, vol.25
, Issue.7
, pp. 319-324
-
-
Freya, T.G.1
Mannellab, C.A.2
-
18
-
-
0019423856
-
Sequence and organization of the human mitochondrial genome
-
DOI 10.1038/290457a0
-
Anderson S., Bankier A. T., Barrell B. G., Sequence and organization of the human mitochondrial genome. Nature 1981 290 5806 457 465 2-s2.0-0019423856 (Pubitemid 11159074)
-
(1981)
Nature
, vol.290
, Issue.5806
, pp. 457-465
-
-
Anderson, S.1
Bankier, A.T.2
Barrell, B.G.3
-
19
-
-
0000204255
-
Maternal inheritance of human mitochondrial DNA
-
DOI 10.1073/pnas.77.11.6715
-
Giles R. E., Blanc H., Cann H. M., Wallace D. C., Maternal inheritance of human mitochondrial DNA. Proceedings of the National Academy of Sciences of the United States of America 1980 77 11 6715 6719 2-s2.0-0000204255 (Pubitemid 11163470)
-
(1980)
Proceedings of the National Academy of Sciences of the United States of America
, vol.77
, Issue.11
, pp. 6715-6719
-
-
Giles, R.E.1
Blanc, H.2
Cann, H.M.3
Wallace, D.C.4
-
20
-
-
33644674439
-
The organization and inheritance of the mitochondrial genome
-
2-s2.0-33644674439 10.1038/nrg1708
-
Chen X. J., Butow R. A., The organization and inheritance of the mitochondrial genome. Nature Reviews Genetics 2005 6 11 815 825 2-s2.0-33644674439 10.1038/nrg1708
-
(2005)
Nature Reviews Genetics
, vol.6
, Issue.11
, pp. 815-825
-
-
Chen, X.J.1
Butow, R.A.2
-
21
-
-
3142717640
-
The low density lipoprotein receptor-related protein 1B retains β-amyloid precursor protein at the cell surface and reduces amyloid-β peptide production
-
DOI 10.1074/jbc.M313893200
-
Cam J. A., Zerbinatti C. V., Knisely J. M., Hecimovic S., Li Y., Bu G., The low density lipoprotein receptor-related protein 1B retains β -amyloid precursor protein at the cell surface and reduces amyloid- β peptide production. The Journal of Biological Chemistry 2004 279 28 29639 29646 2-s2.0-3142717640 10.1074/jbc.M313893200 (Pubitemid 38915847)
-
(2004)
Journal of Biological Chemistry
, vol.279
, Issue.28
, pp. 29639-29646
-
-
Cam, J.A.1
Zerbinatti, C.V.2
Knisely, J.M.3
Hecimovic, S.4
Li, Y.5
Bu, G.6
-
22
-
-
34748897213
-
Amyloid Precursor Protein Regulates Brain Apolipoprotein E and Cholesterol Metabolism through Lipoprotein Receptor LRP1
-
DOI 10.1016/j.neuron.2007.08.008, PII S0896627307006204
-
Liu Q., Zerbinatti C. V., Zhang J., Hoe H. S., Wang B., Cole S. L., Herz J., Muglia L., Bu G., Amyloid precursor protein regulates brain apolipoprotein E and cholesterol metabolism through lipoprotein receptor LRP1. Neuron 2007 56 1 66 78 2-s2.0-34748897213 10.1016/j.neuron.2007.08.008 (Pubitemid 47484175)
-
(2007)
Neuron
, vol.56
, Issue.1
, pp. 66-78
-
-
Liu, Q.1
Zerbinatti, C.V.2
Zhang, J.3
Hoe, H.-S.4
Wang, B.5
Cole, S.L.6
Herz, J.7
Muglia, L.8
Bu, G.9
-
23
-
-
47149115854
-
LRP1 modulates APP trafficking along early compartments of the secretory pathway
-
2-s2.0-47149115854 10.1016/j.nbd.2008.04.006
-
Waldron E., Heilig C., Schweitzer A., Nadella N., Jaeger S., Martin A. M., Weggen S., Brix K., Pietrzik C. U., LRP1 modulates APP trafficking along early compartments of the secretory pathway. Neurobiology of Disease 2008 31 2 188 197 2-s2.0-47149115854 10.1016/j.nbd.2008.04.006
-
(2008)
Neurobiology of Disease
, vol.31
, Issue.2
, pp. 188-197
-
-
Waldron, E.1
Heilig, C.2
Schweitzer, A.3
Nadella, N.4
Jaeger, S.5
Martin, A.M.6
Weggen, S.7
Brix, K.8
Pietrzik, C.U.9
-
25
-
-
0037703255
-
RAGE mediates amyloid-β peptide transport across the blood-brain barrier and accumulation in brain
-
DOI 10.1038/nm890
-
Deane R., Yan S. D., Submamaryan R. K., LaRue B., Jovanovic S., Hogg E., Welch D., Manness L., Lin C., Yu J., Zhu H., Ghiso J., Frangione B., Stern A., Schmidt A. M., Armstrong D. L., Arnold B., Liliensiek B., Nawroth P., Hofman F., Kindy M., Stern D., Zlokovic B., RAGE mediates amyloid- β peptide transport across the blood-brain barrier and accumulation in brain. Nature Medicine 2003 9 7 907 913 2-s2.0-0037703255 10.1038/nm890 (Pubitemid 36889934)
-
(2003)
Nature Medicine
, vol.9
, Issue.7
, pp. 907-913
-
-
Deane, R.1
Yan, S.D.2
Submamaryan, R.K.3
LaRue, B.4
Jovanovic, S.5
Hogg, E.6
Welch, D.7
Manness, L.8
Lin, C.9
Yu, J.10
Zhu, H.11
Ghiso, J.12
Frangione, B.13
Stern, A.14
Schmidt, A.M.15
Armstrong, D.L.16
Arnold, B.17
Liliensiek, B.18
Nawroth, P.19
Hofman, F.20
Kindy, M.21
Stern, D.22
Zlokovic, B.23
more..
-
26
-
-
33644845279
-
Amyloid precursor protein-mediated free radicals and oxidative damage: Implications for the development and progression of Alzheimer's disease
-
2-s2.0-33644845279 10.1111/j.1471-4159.2005.03530.x
-
Reddy P. H., Amyloid precursor protein-mediated free radicals and oxidative damage: implications for the development and progression of Alzheimer's disease. Journal of Neurochemistry 2006 96 1 1 13 2-s2.0-33644845279 10.1111/j.1471-4159.2005.03530.x
-
(2006)
Journal of Neurochemistry
, vol.96
, Issue.1
, pp. 1-13
-
-
Reddy, P.H.1
-
27
-
-
33748283747
-
Accumulation of amyloid precursor protein in the mitochondrial import channels of human Alzheimer's disease brain is associated with mitochondrial dysfunction
-
DOI 10.1523/JNEUROSCI.1469-06.2006
-
Devi L., Prabhu B. M., Galati D. F., Avadhani N. G., Anandatheerthavarada H. K., Accumulation of amyloid precursor protein in the mitochondrial import channels of human Alzheimer's disease brain is associated with mitochondrial dysfunction. Journal of Neuroscience 2006 26 35 9057 9068 2-s2.0-33748283747 10.1523/JNEUROSCI.1469-06.2006 (Pubitemid 44319397)
-
(2006)
Journal of Neuroscience
, vol.26
, Issue.35
, pp. 9057-9068
-
-
Devi, L.1
Prabhu, B.M.2
Galati, D.F.3
Avadhani, N.G.4
Anandatheerthavarada, H.K.5
-
28
-
-
33646152108
-
Mitochondria are a direct site of A β accumulation in Alzheimer's disease neurons: Implications for free radical generation and oxidative damage in disease progression
-
2-s2.0-33646152108 10.1093/hmg/ddl066
-
Manczak M., Anekonda T. S., Henson E., Park B. S., Quinn J., Reddy P. H., Mitochondria are a direct site of A β accumulation in Alzheimer's disease neurons: implications for free radical generation and oxidative damage in disease progression. Human Molecular Genetics 2006 15 9 1437 1449 2-s2.0-33646152108 10.1093/hmg/ddl066
-
(2006)
Human Molecular Genetics
, vol.15
, Issue.9
, pp. 1437-1449
-
-
Manczak, M.1
Anekonda, T.S.2
Henson, E.3
Park, B.S.4
Quinn, J.5
Reddy, P.H.6
-
29
-
-
25444474703
-
Mitochondria take center stage in aging and neurodegeneration
-
DOI 10.1002/ana.20624
-
Beal M. F., Mitochondria take center stage in aging and neurodegeneration. Annals of Neurology 2005 58 4 495 505 2-s2.0-25444474703 10.1002/ana.20624 (Pubitemid 41377212)
-
(2005)
Annals of Neurology
, vol.58
, Issue.4
, pp. 495-505
-
-
Beal, M.F.1
-
30
-
-
34648834538
-
Mitochondrial dysfunction in aging and Alzheimer's disease: Strategies to protect neurons
-
DOI 10.1089/ars.2007.1754
-
Reddy P. H., Mitochondrial dysfunction in aging and Alzheimer's disease: strategies to protect neurons. Antioxidants and Redox Signaling 2007 9 10 1647 1658 2-s2.0-34648834538 10.1089/ars.2007.1754 (Pubitemid 47462968)
-
(2007)
Antioxidants and Redox Signaling
, vol.9
, Issue.10
, pp. 1647-1658
-
-
Reddy, P.H.1
-
32
-
-
77955857970
-
Clinical features and pathogenesis of Alzheimer's disease: Involvement of mitochondria and mitochondrial DNA
-
2-s2.0-77955857970
-
Mancuso M., Orsucci D., LoGerfo A., Calsolaro V., Siciliano G., Clinical features and pathogenesis of Alzheimer's disease: involvement of mitochondria and mitochondrial DNA. Advances in Experimental Medicine and Biology 2010 685 34 44 2-s2.0-77955857970
-
(2010)
Advances in Experimental Medicine and Biology
, vol.685
, pp. 34-44
-
-
Mancuso, M.1
Orsucci, D.2
Logerfo, A.3
Calsolaro, V.4
Siciliano, G.5
-
33
-
-
80053559887
-
Amyloid- β -induced mitochondrial dysfunction impairs the autophagic lysosomal pathway in a tubulin dependent pathway
-
smacardoso@yahoo.com 10.3233/JAD-2011-110423
-
Silva D. F. F., Esteves A. R., Arduino D. M., Oliveira C. R., Cardoso S. M., smacardoso@yahoo.com Amyloid- β -induced mitochondrial dysfunction impairs the autophagic lysosomal pathway in a tubulin dependent pathway. Journal of Alzheimer's Disease 2011 26 3 565 581 10.3233/JAD-2011-110423
-
(2011)
Journal of Alzheimer's Disease
, vol.26
, Issue.3
, pp. 565-581
-
-
Silva, D.F.F.1
Esteves, A.R.2
Arduino, D.M.3
Oliveira, C.R.4
Cardoso, S.M.5
-
34
-
-
81455157378
-
Mitochondrial dysfunction, the beginning of the end in Alzheimer's disease? Separate and synergistic modes of tau and amyloid beta toxicity
-
Eckert A., Schmitt K., Gotz J., Mitochondrial dysfunction, the beginning of the end in Alzheimer's disease? Separate and synergistic modes of tau and amyloid beta toxicity. Alzheimer's Research & Therapy 2011 3, article 15
-
(2011)
Alzheimer's Research & Therapy
, vol.315
-
-
Eckert, A.1
Schmitt, K.2
Gotz, J.3
-
35
-
-
2342628596
-
Differential Expression of Oxidative Phosphorylation Genes in Patients with Alzheimer's Disease: Implications for Early Mitochondrial Dysfunction and Oxidative Damage
-
DOI 10.1385/NMM:5:2:147
-
Manczak M., Park B. S., Jung Y., Reddy P. H., Differential expression of oxide phosphorylation genes in patients with Alzheimer's disease: implications for early mitochondrial dysfunction and oxidative damage. NeuroMolecular Medicine 2004 5 2 147 162 2-s2.0-2342628596 10.1385/NMM:5:2:147 (Pubitemid 38596548)
-
(2004)
NeuroMolecular Medicine
, vol.5
, Issue.2
, pp. 147-162
-
-
Manczak, M.1
Park, B.S.2
Jung, Y.3
Reddy, P.H.4
-
36
-
-
0035341254
-
Mitochondrial abnormalities in Alzheimer's disease
-
Hirai K., Aliev G., Nunomura A., Fujioka H., Russell R. L., Atwood C. S., Johnson A. B., Kress Y., Vinters H. V., Tabaton M., Shimohama S., Cash A. D., Siedlak S. L., Harris P. L. R., Jones P. K., Petersen R. B., Perry G., Smith M. A., Mitochondrial abnormalities in Alzheimer's disease. Journal of Neuroscience 2001 21 9 3017 3023 2-s2.0-0035341254 (Pubitemid 32323483)
-
(2001)
Journal of Neuroscience
, vol.21
, Issue.9
, pp. 3017-3023
-
-
Hirai, K.1
Aliev, G.2
Nunomura, A.3
Fujioka, H.4
Russell, R.L.5
Atwood, C.S.6
Johnson, A.B.7
Kress, Y.8
Vinters, H.V.9
Tabaton, M.10
Shimohama, S.11
Cash, A.D.12
Siedlak, S.L.13
Harris, P.L.R.14
Jones, P.K.15
Petersen, R.B.16
Perry, G.17
Smith, M.A.18
-
37
-
-
1642499152
-
β-Amyloid Peptides Induce Mitochondrial Dysfunction and Oxidative Stress in Astrocytes and Death of Neurons through Activation of NADPH Oxidase
-
DOI 10.1523/JNEUROSCI.4042-03.2004
-
Abramov A. Y., Canevari L., Duchen M. R., beta-amyloid peptides induce mitochondrial dysfunction and oxidative stress in astrocytes and death of neurons. Journal of Neuroscience 2004 24 2 565 575 2-s2.0-1642499152 10.1523/JNEUROSCI.4042-03.2004 (Pubitemid 38112390)
-
(2004)
Journal of Neuroscience
, vol.24
, Issue.2
, pp. 565-575
-
-
Abramov, A.Y.1
Canevari, L.2
Duchen, M.R.3
-
38
-
-
77956206298
-
A mitocentric view of Alzheimer's disease suggests multi-faceted treatments
-
2-s2.0-77956206298 10.3233/JAD-2010-100336
-
Gibson G. E., Shi Q., A mitocentric view of Alzheimer's disease suggests multi-faceted treatments. Journal of Alzheimer's Disease 2010 20 2 S591 S607 2-s2.0-77956206298 10.3233/JAD-2010-100336
-
(2010)
Journal of Alzheimer's Disease
, vol.20
, Issue.2
-
-
Gibson, G.E.1
Shi, Q.2
-
39
-
-
33750347347
-
Mitochondrial dysfunction and oxidative stress in neurodegenerative diseases
-
DOI 10.1038/nature05292, PII NATURE05292
-
Lin M. T., Beal M. F., Mitochondrial dysfunction and oxidative stress in neurodegenerative diseases. Nature 2006 443 7113 787 795 2-s2.0-33750347347 10.1038/nature05292 (Pubitemid 44622683)
-
(2006)
Nature
, vol.443
, Issue.7113
, pp. 787-795
-
-
Lin, M.T.1
Beal, M.F.2
-
40
-
-
0037437192
-
Mitochondrial targeting and a novel transmembrane arrest of Alzheimer's amyloid precursor protein impairs mitochondrial function in neuronal cells
-
DOI 10.1083/jcb.200207030
-
Anandatheerthavarada H. K., Biswas G., Robin M. A., Avadhani N. G., Mitochondrial targeting and a novel transmembrane arrest of Alzheimer's amyloid precursor protein impairs mitochondrial function in neuronal cells. Journal of Cell Biology 2003 161 1 41 54 2-s2.0-0037437192 10.1083/jcb.200207030 (Pubitemid 36459078)
-
(2003)
Journal of Cell Biology
, vol.161
, Issue.1
, pp. 41-54
-
-
Anandatheerthavarada, H.K.1
Biswas, G.2
Robin, M.-A.3
Avadhani, N.G.4
-
41
-
-
28744449206
-
Mitochondrial Aβ: A potential focal point for neuronal metabolic dysfunction in Alzheimer's disease
-
DOI 10.1096/fj.05-3735fje
-
Caspersen C., Wang N., Yao J., Sosunov A., Chen X., Lustbader J. W., Xu H. W., Stern D., McKhann G., Yan S. D., Mitochondrial A β: a potential focal point for neuronal metabolic dysfunction in Alzheimer's disease. The FASEB Journal 2005 19 14 2040 2041 2-s2.0-28744449206 10.1096/fj.05-3735fje (Pubitemid 41759758)
-
(2005)
FASEB Journal
, vol.19
, Issue.14
, pp. 2040-2041
-
-
Caspersen, C.1
Wang, N.2
Yao, J.3
Sosunov, A.4
Chen, X.5
Lustbader, J.W.6
Xu, H.W.7
Stern, D.8
McKhann, G.9
Yan, S.D.10
-
42
-
-
1542284022
-
Intra- and extracellular Aβ and PHF in clinically evaluated cases of Alzheimer's disease
-
Fernández-Vizarra P., Fernández A. P., Castro-Blanco S., Serrano J., Bentura M. L., Martínez-Murillo R., Martinez A., Rodrigo J., rodmart@cajal.csic.es Intra- and extracellular A β and PHF in clinically evaluated cases of Alzheimer's disease. Histology and Histopathology 2004 19 3 823 844 (Pubitemid 38855065)
-
(2004)
Histology and Histopathology
, vol.19
, Issue.3
, pp. 823-844
-
-
Fernandez-Vizarra, P.1
Fernandez, A.P.2
Castro-Blanco, S.3
Serrano, J.4
Bentura, M.L.5
Martinez-Murillo, R.6
Martinez, A.7
Rodrigo, J.8
-
43
-
-
0025024024
-
Cytochrome oxidase deficiency in Alzheimer's disease
-
Parker W. D., Filley C. M., Parks J. K., Cytochrome oxidase deficiency in Alzheimer's disease. Neurology 1990 40 8 1302 1303 2-s2.0-0025024024 (Pubitemid 20244999)
-
(1990)
Neurology
, vol.40
, Issue.8
, pp. 1302-1303
-
-
Parker Jr., W.D.1
Filley, C.M.2
Parks, J.K.3
-
44
-
-
0029055772
-
Cytochrome c oxidase in Alzheimer's disease brain: Purification and characterization
-
2-s2.0-0029055772
-
Parker W. D., Parks J. K., Cytochrome c oxidase in Alzheimer's disease brain: purification and characterization. Neurology 1995 45 3 482 486 2-s2.0-0029055772
-
(1995)
Neurology
, vol.45
, Issue.3
, pp. 482-486
-
-
Parker, W.D.1
Parks, J.K.2
-
45
-
-
3042513691
-
Mitochondria dysfunction of Alzheimer's disease cybrids enhances Aβ toxicity
-
DOI 10.1111/j.1471-4159.2004.02438.x
-
Cardoso S. M., Santana I., Swerdlow R. H., Oliveira C. R., Mitochondria dysfunction of Alzheimer's disease cybrids enhances A β toxicity. Journal of Neurochemistry 2004 89 6 1417 1426 2-s2.0-3042513691 10.1111/j.1471-4159. 2004.02438.x (Pubitemid 38802663)
-
(2004)
Journal of Neurochemistry
, vol.89
, Issue.6
, pp. 1417-1426
-
-
Cardoso, S.M.1
Santana, I.2
Swerdlow, R.H.3
Oliveira, C.R.4
-
46
-
-
73949142307
-
Amyloid- β and tau synergistically impair the oxidative phosphorylation system in triple transgenic Alzheimer's disease mice
-
2-s2.0-73949142307 10.1073/pnas.0905529106
-
Rhein V., Song X., Wiesner A., Ittner L. M., Baysang G., Meier F., Ozmen L., Bluethmann H., Dröse S., Brandt U., Savaskan E., Czech C., Götz J., Eckert A., Amyloid- β and tau synergistically impair the oxidative phosphorylation system in triple transgenic Alzheimer's disease mice. Proceedings of the National Academy of Sciences of the United States of America 2009 106 47 20057 20062 2-s2.0-73949142307 10.1073/pnas.0905529106
-
(2009)
Proceedings of the National Academy of Sciences of the United States of America
, vol.106
, Issue.47
, pp. 20057-20062
-
-
Rhein, V.1
Song, X.2
Wiesner, A.3
Ittner, L.M.4
Baysang, G.5
Meier, F.6
Ozmen, L.7
Bluethmann, H.8
Dröse, S.9
Brandt, U.10
Savaskan, E.11
Czech, C.12
Götz, J.13
Eckert, A.14
-
47
-
-
0031020993
-
Amyloid β-peptide impairs glucose transport in hippocampal and cortical neurons: Involvement of membrane lipid peroxidation
-
Mark R. J., Pang Z., Geddes J. W., Uchida K., Mattson M. P., Amyloid β -peptide impairs glucose transport in hippocampal and cortical neurons: involvement of membrane lipid peroxidation. Journal of Neuroscience 1997 17 3 1046 1054 2-s2.0-0031020993 (Pubitemid 27043963)
-
(1997)
Journal of Neuroscience
, vol.17
, Issue.3
, pp. 1046-1054
-
-
Mark, R.J.1
Pang, Z.2
Geddes, J.W.3
Uchida, K.4
Mattson, M.P.5
-
48
-
-
3943092621
-
Pathways towards and away from Alzheimer's disease
-
DOI 10.1038/nature02621
-
Mattson M. P., Pathways towards and away from Alzheimer's disease. Nature 2004 430 7000 631 639 2-s2.0-3943092621 10.1038/nature02621 (Pubitemid 39061671)
-
(2004)
Nature
, vol.430
, Issue.7000
, pp. 631-639
-
-
Mattson, M.P.1
-
49
-
-
79952901937
-
Cyclophilin D deficiency improves mitochondrial function and learning/memory in aging Alzheimer disease mouse model
-
2-s2.0-63849179225 10.1016/j.neurobiolaging.2009.03.003
-
Du H., Guo L., Zhang W., Rydzewska M., Yan S., Cyclophilin D deficiency improves mitochondrial function and learning/memory in aging Alzheimer disease mouse model. Neurobiology of Aging 2009 32 398 406 2-s2.0-63849179225 10.1016/j.neurobiolaging.2009.03.003
-
(2009)
Neurobiology of Aging
, vol.32
, pp. 398-406
-
-
Du, H.1
Guo, L.2
Zhang, W.3
Rydzewska, M.4
Yan, S.5
-
50
-
-
33746103234
-
Mitochondrial dysfunction induced by disease relevant AβPP and tau protein mutations
-
Keil U., Hauptmann S., Bonert A., Scherping I., Eckert A., Müller W. E., Mitochondrial dysfunction induced by disease relevant A β PP and tau protein mutations. Journal of Alzheimer's Disease 2006 9 2 139 146 2-s2.0-33746103234 (Pubitemid 44078641)
-
(2006)
Journal of Alzheimer's Disease
, vol.9
, Issue.2
, pp. 139-146
-
-
Keil, U.1
Hauptmann, S.2
Bonert, A.3
Scherping, I.4
Eckert, A.5
Muller, W.E.6
-
51
-
-
71749121998
-
Mitochondrial dysfunction is a trigger of Alzheimer's disease pathophysiology
-
2-s2.0-71749121998 10.1016/j.bbadis.2009.10.006
-
Moreira P. I., Carvalho C., Zhu X., Smith M. A., Perry G., Mitochondrial dysfunction is a trigger of Alzheimer's disease pathophysiology. Biochimica et Biophysica Acta 2010 1802 1 2 10 2-s2.0-71749121998 10.1016/j.bbadis.2009.10.006
-
(2010)
Biochimica et Biophysica Acta
, vol.1802
, Issue.1
, pp. 2-10
-
-
Moreira, P.I.1
Carvalho, C.2
Zhu, X.3
Smith, M.A.4
Perry, G.5
-
52
-
-
33644861975
-
Common structure and toxic function of amyloid oligomers implies a common mechanism of pathogenesis
-
PII 0000611420060124100013
-
Glabe C. G., Kayed R., Common structure and toxic function of amyloid oligomers implies a common mechanism of pathogenesis. Neurology 2006 66 2 S74 S78 2-s2.0-33644861975 (Pubitemid 43739989)
-
(2006)
Neurology
, vol.66
, Issue.2 SUPPL. 1
-
-
Glabe, C.G.1
Kayed, R.2
-
53
-
-
29444436680
-
Lipid- and receptor-binding regions of apolipoprotein E4 fragments act in concert to cause mitochondrial dysfunction and neurotoxicity
-
DOI 10.1073/pnas.0508254102
-
Chang S., Ma T. R., Miranda R. D., Balestra M. E., Mahley R. W., Huang Y., Lipid- and receptor-binding regions of apolipoprotein E4 fragments act in concert to cause mitochondrial dysfunction and neurotoxicity. Proceedings of the National Academy of Sciences of the United States of America 2005 102 51 18694 18699 2-s2.0-29444436680 10.1073/pnas.0508254102 (Pubitemid 43011288)
-
(2005)
Proceedings of the National Academy of Sciences of the United States of America
, vol.102
, Issue.51
, pp. 18694-18699
-
-
Chang, S.1
Ma, T.R.2
Miranda, R.D.3
Balestra, M.E.4
Mahley, R.W.5
Huang, Y.6
-
54
-
-
77956203927
-
Is Alzheimer's disease a disorder of mitochondria-associated membranes?
-
2-s2.0-77956203927 10.3233/JAD-2010-100495
-
Schon E. A., Area-Gomez E., Is Alzheimer's disease a disorder of mitochondria-associated membranes? Journal of Alzheimer's Disease 2010 20 2 S281 S292 2-s2.0-77956203927 10.3233/JAD-2010-100495
-
(2010)
Journal of Alzheimer's Disease
, vol.20
, Issue.2
-
-
Schon, E.A.1
Area-Gomez, E.2
-
55
-
-
36849040009
-
Evolving insight into the role of mitochondrial DNA mutations in aging
-
DOI 10.1016/j.exger.2007.09.010, PII S0531556507002227, Annual Reviews in Biogerontology
-
Kujoth G. C., Prolla T. A., Evolving insight into the role of mitochondrial DNA mutations in aging. Experimental Gerontology 2008 43 1 20 23 2-s2.0-36849040009 10.1016/j.exger.2007.09.010 (Pubitemid 350235154)
-
(2008)
Experimental Gerontology
, vol.43
, Issue.1
, pp. 20-23
-
-
Kujoth, G.C.1
Prolla, T.A.2
-
56
-
-
33847245332
-
The role of mitochondrial DNA mutations in mammalian aging
-
ARTICLE E24 2-s2.0-34147181042 10.1371/journal.pgen.0030024
-
Kujoth G. C., Bradshaw P. C., Haroon S., Prolla T. A., The role of mitochondrial DNA mutations in mammalian aging. PLoS Genetics 2007 3 2, article e24 2-s2.0-34147181042 10.1371/journal.pgen.0030024
-
(2007)
PLoS Genetics
, vol.3
, Issue.2
-
-
Kujoth, G.C.1
Bradshaw, P.C.2
Haroon, S.3
Prolla, T.A.4
-
57
-
-
84856615989
-
Modelling mitochondrial dysfunction in mice
-
Dogan S. A., Trifunovic A., Modelling mitochondrial dysfunction in mice. Physiological Research 2011 60 61 70
-
(2011)
Physiological Research
, vol.60
, pp. 61-70
-
-
Dogan, S.A.1
Trifunovic, A.2
-
58
-
-
77953733762
-
Mitochondrial energy metabolism and ageing
-
2-s2.0-77953733762 10.1016/j.bbabio.2010.01.004
-
Bratic I., Trifunovic A., Mitochondrial energy metabolism and ageing. Biochimica et Biophysica Acta 2010 1797 6-7 961 967 2-s2.0-77953733762 10.1016/j.bbabio.2010.01.004
-
(2010)
Biochimica et Biophysica Acta
, vol.1797
, Issue.6-7
, pp. 961-967
-
-
Bratic, I.1
Trifunovic, A.2
-
59
-
-
33744912521
-
Mitochondrial and nuclear DNA-repair capacity of various brain regions in mouse is altered in an age-dependent manner
-
DOI 10.1016/j.neurobiolaging.2005.06.002, PII S0197458005001739
-
Imam S. Z., Karahalil B., Hogue B. A., Souza-Pinto N. C., Bohr V. A., Mitochondrial and nuclear DNA-repair capacity of various brain regions in mouse is altered in an age-dependent manner. Neurobiology of Aging 2006 27 8 1129 1136 2-s2.0-33744912521 10.1016/j.neurobiolaging.2005.06.002 (Pubitemid 43850641)
-
(2006)
Neurobiology of Aging
, vol.27
, Issue.8
, pp. 1129-1136
-
-
Imam, S.Z.1
Karahalil, B.2
Hogue, B.A.3
Souza-Pinto, N.C.4
Bohr, V.A.5
-
60
-
-
0031984178
-
A ginkgo biloba extract (EGb 761) prevents mitochondrial aging by protecting against oxidative stress
-
DOI 10.1016/S0891-5849(97)00228-1, PII S0891584997002281
-
Sastre J., Millan A., De La Asuncion J. G., Pla R., Juan G., Pallardo F. V., O'Connor E., Martin J. A., Droy-Lefaix M. T., Viña J., A ginkgo biloba extract (EGb 761) prevents mitochondrial aging by protecting against oxidative stress. Free Radical Biology and Medicine 1998 24 2 298 304 2-s2.0-0031984178 10.1016/S0891-5849(97)00228-1 (Pubitemid 28008808)
-
(1998)
Free Radical Biology and Medicine
, vol.24
, Issue.2
, pp. 298-304
-
-
Sastre, J.1
Millan, A.2
De La Asuncion, J.G.3
Pla, R.4
Juan, G.5
Pallardo, F.V.6
O'Connor, E.7
Martin, J.A.8
Droy-Lefaix, M.-T.9
Vina, J.10
-
61
-
-
0037081814
-
High aggregate burden of somatic mtDNA point mutations in aging and Alzheimer's disease brain
-
Lin M. T., Simon D. K., Ahn C. H., Kim L. M., Flint Beal M., High aggregate burden of somatic mtDNA point mutations in aging and Alzheimer's disease brain. Human Molecular Genetics 2002 11 2 133 145 2-s2.0-0037081814 (Pubitemid 34157005)
-
(2002)
Human Molecular Genetics
, vol.11
, Issue.2
, pp. 133-145
-
-
Lin, M.T.1
Simon, D.K.2
Ahn, C.H.3
Kim, L.M.4
Flint Beal, M.5
-
62
-
-
3242668604
-
Alzheimer's brains harbor somatic mtDNA control-region mutations that suppress mitochondrial transcription and replication
-
DOI 10.1073/pnas.0403649101
-
Coskun P. E., Beal M. F., Wallace D. C., Alzheimer's brains harbor somatic mtDNA control-region mutations that suppress mitochondrial transcription and replication. Proceedings of the National Academy of Sciences of the United States of America 2004 101 29 10726 10731 2-s2.0-3242668604 10.1073/pnas. 0403649101 (Pubitemid 38955810)
-
(2004)
Proceedings of the National Academy of Sciences of the United States of America
, vol.101
, Issue.29
, pp. 10726-10731
-
-
Coskun, P.E.1
Beal, M.F.2
Wallace, D.C.3
-
63
-
-
77956197653
-
Systemic mitochondrial dysfunction and the etiology of Alzheimer's disease and down syndrome dementia
-
2-s2.0-77956197653 10.3233/JAD-2010-100351
-
Coskun P. E., Wyrembak J., Derbereva O., Melkonian G., Doran E., Lott I. T., Head E., Cotman C. W., Wallace D. C., Systemic mitochondrial dysfunction and the etiology of Alzheimer's disease and down syndrome dementia. Journal of Alzheimer's Disease 2010 20 2 S293 S310 2-s2.0-77956197653 10.3233/JAD-2010- 100351
-
(2010)
Journal of Alzheimer's Disease
, vol.20
, Issue.2
-
-
Coskun, P.E.1
Wyrembak, J.2
Derbereva, O.3
Melkonian, G.4
Doran, E.5
Lott, I.T.6
Head, E.7
Cotman, C.W.8
Wallace, D.C.9
-
64
-
-
0027200741
-
Mitochondrial DNA variants observed in Alzheimer disease and Parkinson disease patients
-
DOI 10.1006/geno.1993.1299
-
Shoffner J. M., Brown M. D., Torroni A., Lott M. T., Cabell M. F., Mirra S. S., Beal M. F., Yang C. C., Gearing M., Salvo R., Watts R. L., Juncos J. L., Hansen L. A., Crain B. J., Fayad M., Reckord C. L., Wallace D. C., Mitochondrial DNA variants observed in Alzheimer disease and Parkinson disease patients. Genomics 1993 17 1 171 184 2-s2.0-0027200741 10.1006/geno.1993.1299 (Pubitemid 23205074)
-
(1993)
Genomics
, vol.17
, Issue.1
, pp. 171-184
-
-
Shoffner, J.M.1
Brown, M.D.2
Torroni, A.3
Lott, M.T.4
Cabell, M.F.5
Mirra, S.S.6
Beal, M.F.7
Yang, C.-C.8
Gearing, M.9
Salvo, R.10
Watts, R.L.11
Juncos, J.L.12
Hansen, L.A.13
Crain, B.J.14
Fayad, M.15
Reckord, C.L.16
Wallace, D.C.17
-
65
-
-
34347353834
-
Mitochondria in cybrids containing mtDNA from persons with mitochondriopathies
-
DOI 10.1002/jnr.21167
-
Swerdlow R. H., Mitochondria in cybrids containing mtDNA from persons with mitochondriopathies. Journal of Neuroscience Research 2007 85 15 3416 3428 2-s2.0-34347353834 10.1002/jnr.21167 (Pubitemid 350058530)
-
(2007)
Journal of Neuroscience Research
, vol.85
, Issue.15
, pp. 3416-3428
-
-
Swerdlow, R.H.1
-
66
-
-
33847049400
-
Alzheimer disease: Amyloidogenesis, the presenilins and animal models
-
DOI 10.1016/j.bbadis.2006.12.001, PII S0925443906002675
-
Newman M., Musgrave I. F., Lardelli M., Alzheimer's disease: amyloidogenesis, the presenilins and animal models. Biochimica et Biophysica Acta 2007 1772 9 285 297 (Pubitemid 46275437)
-
(2007)
Biochimica et Biophysica Acta - Molecular Basis of Disease
, vol.1772
, Issue.3
, pp. 285-297
-
-
Newman, M.1
Musgrave, F.I.2
Lardelli, M.3
-
67
-
-
0036121084
-
Increased serum levels of CD95 in Alzheimer's disease
-
DOI 10.1159/000048650
-
Richartz E., Noda S., Schott K., Günthner A., Lewczuk P., Bartels M., Increased serum levels of CD95 in Alzheimer's disease. Dementia and Geriatric Cognitive Disorders 2002 13 3 178 182 2-s2.0-0036121084 10.1159/000048650 (Pubitemid 34224937)
-
(2002)
Dementia and Geriatric Cognitive Disorders
, vol.13
, Issue.3
, pp. 178-182
-
-
Richartz, E.1
Noda, S.2
Schott, K.3
Gunthner, A.4
Lewczuk, P.5
Bartels, M.6
-
68
-
-
0043172468
-
4-Hydroxynonenal and neurodegenerative diseases
-
DOI 10.1016/S0098-2997(03)00024-4
-
Zarkovic K., 4-Hydroxynonenal and neurodegenerative diseases. Molecular Aspects of Medicine 2003 24 4-5 293 303 2-s2.0-0043172468 10.1016/S0098-2997(03) 00024-4 (Pubitemid 36945029)
-
(2003)
Molecular Aspects of Medicine
, vol.24
, Issue.4-5
, pp. 293-303
-
-
Zarkovic, K.1
-
69
-
-
79959305691
-
Mitochondria: The next neurodegeneration
-
Schon E. A., Przedborski S., Mitochondria: the next neurodegeneration. Neuron 2011 70 1033 1053
-
(2011)
Neuron
, vol.70
, pp. 1033-1053
-
-
Schon, E.A.1
Przedborski, S.2
-
70
-
-
79955972587
-
Trafficking kinesin protein (TRAK)-mediated transport of mitochondria in axons of hippocampal neurons
-
anne.stephenson@pharmacy.ac.uk 10.1074/jbc.M111.236018
-
Brickley K., Stephenson F. A., anne.stephenson@pharmacy.ac.uk Trafficking kinesin protein (TRAK)-mediated transport of mitochondria in axons of hippocampal neurons. The Journal of Biological Chemistry 2011 286 20 18079 18092 10.1074/jbc.M111.236018
-
(2011)
The Journal of Biological Chemistry
, vol.286
, Issue.20
, pp. 18079-18092
-
-
Brickley, K.1
Stephenson, F.A.2
-
71
-
-
33847686377
-
Proteomic and functional alterations in brain mitochondria from Tg2576 mice occur before amyloid plaque deposition
-
DOI 10.1002/pmic.200600728
-
Gillardon F., Rist W., Kussmaul L., Vogel J., Berg M., Danzer K., Kraut N., Hengerer B., Proteomic and functional alterations in brain mitochondria from Tg2576 mice occur before amyloid plaque deposition. Proteomics 2007 7 4 605 616 2-s2.0-33847686377 10.1002/pmic.200600728 (Pubitemid 46362624)
-
(2007)
Proteomics
, vol.7
, Issue.4
, pp. 605-616
-
-
Gillardon, F.1
Rist, W.2
Kussmaul, L.3
Vogel, J.4
Berg, M.5
Danzer, K.6
Kraut, N.7
Hengerer, B.8
-
72
-
-
77649184822
-
Mitochondrial medicine for neurodegenerative diseases
-
2-s2.0-77649184822 10.1016/j.biocel.2010.01.004
-
Du H., Yan S. S., Mitochondrial medicine for neurodegenerative diseases. International Journal of Biochemistry and Cell Biology 2010 42 5 560 572 2-s2.0-77649184822 10.1016/j.biocel.2010.01.004
-
(2010)
International Journal of Biochemistry and Cell Biology
, vol.42
, Issue.5
, pp. 560-572
-
-
Du, H.1
Yan, S.S.2
-
73
-
-
40449090190
-
Soluble beta-amyloid leads to mitochondrial defects in amyloid precursor protein and tau transgenic mice
-
DOI 10.1159/000113689
-
Eckert A., Hauptmann S., Scherping I., Rhein V., Müller-Spahn F., Götz J., Müller W. E., Soluble beta-amyloid leads to mitochondrial defects in amyloid precursor protein and tau transgenic mice. Neurodegenerative Diseases 2008 5 3-4 157 159 2-s2.0-40449090190 10.1159/000113689 (Pubitemid 351347837)
-
(2008)
Neurodegenerative Diseases
, vol.5
, Issue.3-4
, pp. 157-159
-
-
Eckert, A.1
Hauptmann, S.2
Scherping, I.3
Rhein, V.4
Muller-Spahn, F.5
Gotz, J.6
Muller, W.E.7
-
74
-
-
70149093436
-
Mitochondrial bioenergetic deficit precedes Alzheimer's pathology in female mouse model of Alzheimer's disease
-
2-s2.0-70149093436 10.1073/pnas.0903563106
-
Yao J., Irwin R. W., Zhao L., Nilsen J., Hamilton R. T., Brinton R. D., Mitochondrial bioenergetic deficit precedes Alzheimer's pathology in female mouse model of Alzheimer's disease. Proceedings of the National Academy of Sciences of the United States of America 2009 106 34 14670 14675 2-s2.0-70149093436 10.1073/pnas.0903563106
-
(2009)
Proceedings of the National Academy of Sciences of the United States of America
, vol.106
, Issue.34
, pp. 14670-14675
-
-
Yao, J.1
Irwin, R.W.2
Zhao, L.3
Nilsen, J.4
Hamilton, R.T.5
Brinton, R.D.6
-
75
-
-
53549129483
-
Cyclophilin D deficiency attenuates mitochondrial and neuronal perturbation and ameliorates learning and memory in Alzheimer's disease
-
2-s2.0-53549129483 10.1038/nm.1868
-
Du H., Guo L., Fang F., Chen D., A Sosunov A., M McKhann G., Yan Y., Wang C., Zhang H., Molkentin J. D., Gunn-Moore F. J., Vonsattel J. P., Arancio O., Chen J. X., Yan S. D., Cyclophilin D deficiency attenuates mitochondrial and neuronal perturbation and ameliorates learning and memory in Alzheimer's disease. Nature Medicine 2008 14 10 1097 1105 2-s2.0-53549129483 10.1038/nm.1868
-
(2008)
Nature Medicine
, vol.14
, Issue.10
, pp. 1097-1105
-
-
Du, H.1
Guo, L.2
Fang, F.3
Chen, D.4
Sosunov A, A.5
McKhann G, M.6
Yan, Y.7
Wang, C.8
Zhang, H.9
Molkentin, J.D.10
Gunn-Moore, F.J.11
Vonsattel, J.P.12
Arancio, O.13
Chen, J.X.14
Yan, S.D.15
-
76
-
-
67650732998
-
Impaired balance of mitochondrial fission and fusion in Alzheimer's disease
-
2-s2.0-67650732998 10.1523/JNEUROSCI.1357-09.2009
-
Wang X., Su B., Lee H. G., Li X., Perry G., Smith M. A., Zhu X., Impaired balance of mitochondrial fission and fusion in Alzheimer's disease. Journal of Neuroscience 2009 29 28 9090 9103 2-s2.0-67650732998 10.1523/JNEUROSCI.1357-09. 2009
-
(2009)
Journal of Neuroscience
, vol.29
, Issue.28
, pp. 9090-9103
-
-
Wang, X.1
Su, B.2
Lee, H.G.3
Li, X.4
Perry, G.5
Smith, M.A.6
Zhu, X.7
-
77
-
-
42649145866
-
Megalin mediates the transport of leptin across the blood-CSF barrier
-
DOI 10.1016/j.neurobiolaging.2007.01.008, PII S0197458007000097
-
Dietrich M. O., Spuch C., Antequera D., Rodal I., de Yébenes J. G., Molina J. A., Bermejo F., Carro E., Megalin mediates the transport of leptin across the blood-CSF barrier. Neurobiology of Aging 2008 29 6 902 912 2-s2.0-42649145866 10.1016/j.neurobiolaging.2007.01.008 (Pubitemid 351601900)
-
(2008)
Neurobiology of Aging
, vol.29
, Issue.6
, pp. 902-912
-
-
Dietrich, M.O.1
Spuch, C.2
Antequera, D.3
Rodal, I.4
De Yebenes, J.G.5
Molina, J.A.6
Bermejo, F.7
Carro, E.8
-
78
-
-
34147183707
-
Role of the blood-brain barrier in the pathogenesis of Alzheimer's disease
-
DOI 10.2174/156720507780362245
-
Deane R., Zlokovic B. V., Role of the blood-brain barrier in the pathogenesis of Alzheimer's disease. Current Alzheimer Research 2007 4 2 191 197 2-s2.0-34147183707 10.2174/156720507780362245 (Pubitemid 46562394)
-
(2007)
Current Alzheimer Research
, vol.4
, Issue.2
, pp. 191-197
-
-
Deane, R.1
Zlokovic, B.V.2
-
79
-
-
84866442633
-
Expression and functions of LRP-2 in central nervous system: Progress in understanding its regulation and the potential use for treatment of neurodegenerative diseases
-
Spuch C., Navarro C., Expression and functions of LRP-2 in central nervous system: progress in understanding its regulation and the potential use for treatment of neurodegenerative diseases. Recent Pat Immunology, Endocrine and metabolic Agents in Medicinal Chemistry 2010 10 249 254
-
(2010)
Recent Pat Immunology, Endocrine and Metabolic Agents in Medicinal Chemistry
, vol.10
, pp. 249-254
-
-
Spuch, C.1
Navarro, C.2
-
80
-
-
78649374892
-
Expression and functions of LRP-2 in central nervous system: Progress in understanding its regulation and the potential use for treatment of neurodegenerative diseases
-
Spuch C., Navarro C., Expression and functions of LRP-2 in central nervous system: progress in understanding its regulation and the potential use for treatment of neurodegenerative diseases. Endocrine, Metabolic & Immune Drug Discovery 2010 4 190 205
-
(2010)
Endocrine, Metabolic & Immune Drug Discovery
, vol.4
, pp. 190-205
-
-
Spuch, C.1
Navarro, C.2
-
81
-
-
0142042439
-
Stress protein expression in the Alzheimer-diseased choroid plexus
-
Anthony S. G., Schipper H. M., Tavares R., Hovanesian V., Cortez S. C., Stopa E. G., Johanson C. E., Stress protein expression in the Alzheimer-diseased choroid plexus. Endocrine, Metabolic & Immune Drug Discovery 2003 5 171 177 (Pubitemid 37279548)
-
(2003)
Journal of Alzheimer's Disease
, vol.5
, Issue.3
, pp. 171-177
-
-
Anthony, S.G.1
Schipper, H.M.2
Tavares, R.3
Hovanesian, V.4
Cortez, S.C.5
Stopa, E.G.6
Johanson, C.E.7
-
82
-
-
69949118812
-
Oxidative stress damage and oxidative stress responses in the choroid plexus in Alzheimer's disease
-
2-s2.0-69949118812 10.1007/s00401-009-0574-4
-
Perez-Gracia E., Blanco R., Carmona M., Carro E., Ferrer I., Oxidative stress damage and oxidative stress responses in the choroid plexus in Alzheimer's disease. Acta Neuropathologica 2009 118 4 497 504 2-s2.0-69949118812 10.1007/s00401-009-0574-4
-
(2009)
Acta Neuropathologica
, vol.118
, Issue.4
, pp. 497-504
-
-
Perez-Gracia, E.1
Blanco, R.2
Carmona, M.3
Carro, E.4
Ferrer, I.5
-
83
-
-
77954957989
-
A β accumulation in choroid plexus is associated with mitochondrial-induced apoptosis
-
carroeva@yahoo.es 10.1016/j.neurobiolaging.2008.08.017
-
Vargas T., Ugalde C., Spuch C., Antequera D., Morán M. J., Martín M. A., Ferrer I., Bermejo-Pareja F., Carro E., carroeva@yahoo.es A β accumulation in choroid plexus is associated with mitochondrial-induced apoptosis. Neurobiology of Aging 2010 31 9 1569 1581 10.1016/j.neurobiolaging. 2008.08.017
-
(2010)
Neurobiology of Aging
, vol.31
, Issue.9
, pp. 1569-1581
-
-
Vargas, T.1
Ugalde, C.2
Spuch, C.3
Antequera, D.4
Morán, M.J.5
Martín, M.A.6
Ferrer, I.7
Bermejo-Pareja, F.8
Carro, E.9
-
84
-
-
77951669734
-
Gelsolin restores A β -Induced alterations in choroid plexus epithelium
-
vargalon@yahoo.es eeara@yahoo.es cugalde@h12o.es carlos.spuch@gamil.com 805405 10.1155/2010/805405
-
Vargas T., vargalon@yahoo.es Antequera D., eeara@yahoo.es Ugalde C., cugalde@h12o.es Spuch C., carlos.spuch@gamil.com Gelsolin restores A β -Induced alterations in choroid plexus epithelium. Journal of Biomedicine and Biotechnology 2010 2010 7 805405 10.1155/2010/805405
-
(2010)
Journal of Biomedicine and Biotechnology
, vol.2010
, pp. 7
-
-
Vargas, T.1
Antequera, D.2
Ugalde, C.3
Spuch, C.4
-
85
-
-
69749084874
-
Cytoplasmic gelsolin increases mitochondrial activity and reduces A β burden in a mouse model of Alzheimer's disease
-
2-s2.0-69749084874 10.1016/j.nbd.2009.06.018
-
Antequera D., Vargas T., Ugalde C., Spuch C., Molina J. A., Ferrer I., Bermejo-Pareja F., Carro E., Cytoplasmic gelsolin increases mitochondrial activity and reduces A β burden in a mouse model of Alzheimer's disease. Neurobiology of Disease 2009 36 1 42 50 2-s2.0-69749084874 10.1016/j.nbd.2009. 06.018
-
(2009)
Neurobiology of Disease
, vol.36
, Issue.1
, pp. 42-50
-
-
Antequera, D.1
Vargas, T.2
Ugalde, C.3
Spuch, C.4
Molina, J.A.5
Ferrer, I.6
Bermejo-Pareja, F.7
Carro, E.8
-
86
-
-
39149122810
-
Amyloid beta, mitochondrial dysfunction and synaptic damage: Implications for cognitive decline in aging and Alzheimer's disease
-
2-s2.0-39149122810 10.1016/j.molmed.2007.12.002
-
Reddy P. H., Beal M. F., Amyloid beta, mitochondrial dysfunction and synaptic damage: implications for cognitive decline in aging and Alzheimer's disease. Trends in Molecular Medicine 2008 14 2 45 53 2-s2.0-39149122810 10.1016/j.molmed.2007.12.002
-
(2008)
Trends in Molecular Medicine
, vol.14
, Issue.2
, pp. 45-53
-
-
Reddy, P.H.1
Beal, M.F.2
|