메뉴 건너뛰기




Volumn 4 S, Issue 3, 2012, Pages 916-931

Insulin resistance, metabolic stress, and atherosclerosis

Author keywords

Atherosclerosis; Diabetes; Insulin signaling; Review

Indexed keywords

INSULIN; INSULIN RECEPTOR;

EID: 84867766778     PISSN: 19450516     EISSN: 19450524     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (61)

References (165)
  • 1
    • 0026110135 scopus 로고
    • Banting lecture 1990. Beta-cells in type II diabetes mellitus
    • D Porte, Jr.: Banting lecture 1990. Beta-cells in type II diabetes mellitus. Diabetes 40, 166-180 (1991)
    • (1991) Diabetes , vol.40 , pp. 166-180
    • Porte Jr., D.1
  • 2
    • 17144380822 scopus 로고    scopus 로고
    • The metabolic syndrome
    • DOI 10.1016/S0140-6736(05)66378-7
    • R. Eckel, S. Grundy, P Z Zimmet: The metabolic syndrome. Lancet 365, 1415-1428 (2005) (Pubitemid 40523737)
    • (2005) Lancet , vol.365 , Issue.9468 , pp. 1415-1428
    • Eckel, R.H.1    Grundy, S.M.2    Zimmet, P.Z.3
  • 3
    • 84888022233 scopus 로고    scopus 로고
    • American diabetes association. http://www.diabetes.org/diabetes-basics/ diabetes-statistics/(2011)
    • (2011)
  • 4
    • 33645074450 scopus 로고    scopus 로고
    • Etiology of insulin resistance
    • K. Petersen, G I Shulman: Etiology of insulin resistance. Am J Med 119, S10-S16 (2006)
    • (2006) Am J Med , vol.119
    • Petersen, K.1    Shulman, G.I.2
  • 6
    • 0028030813 scopus 로고
    • Insulin-mediated skeletal muscle vasodilation is nitric oxide dependent. A novel action of insulin to increase nitric oxide release
    • H. Steinberg, G Brechtel. A Johnson, N Fineberg, A D Baron: Insulin-mediated skeletal muscle vasodilation is nitric oxide dependent. A novel action of insulin to increase nitric oxide release. J Clin Invet 94, 1172-1179 (1994)
    • (1994) J Clin Invet , vol.94 , pp. 1172-1179
    • Steinberg, H.1    Brechtel, G.2    Johnson, A.3    Fineberg, N.4    Baron, A.D.5
  • 7
    • 0028970042 scopus 로고
    • Cell biology of atherosclerosis
    • R Ross: Cell biology of atherosclerosis. Annu Rev Physiol 57, 791-804 (1995)
    • (1995) Annu Rev Physiol , vol.57 , pp. 791-804
    • Ross, R.1
  • 8
  • 9
    • 0030871260 scopus 로고    scopus 로고
    • Vascular dysfunction in diabetes mellitus
    • E. Feener, G L King: Vascular dysfunction in diabetes mellitus. Lancet 350 Suppl 1, SI9-SI13 (1997) (Pubitemid 27303531)
    • (1997) Lancet , vol.350 , Issue.9072 SUPPL.
    • Feener, E.P.1    King, G.L.2
  • 10
    • 3242695011 scopus 로고    scopus 로고
    • Insulin resistance and the endothelium
    • DOI 10.1016/j.amjmed.2004.02.042, PII S0002934304002724
    • W. Hsueh, C. Lyon, M J Quinones: Insulin resistance and the endothelium. Am J Med 117, 109-17 (2004) (Pubitemid 38953731)
    • (2004) American Journal of Medicine , vol.117 , Issue.2 , pp. 109-117
    • Hsueh, W.A.1    Lyon, C.J.2    Quinones, M.J.3
  • 11
    • 0031980770 scopus 로고    scopus 로고
    • Distinct localization of GLUT-1, -3, and -5 in human monocyte-derived macrophages: Effects of cell activation
    • D Malide. T M Davies-Hill, M Levine, I A Simpson: Distinct localization of GLUT-1, -3, and -5 in human monocyte-derived macrophages: effects of cell activation. Am J Physiol 274, E516-E526 (1998)
    • (1998) Am J Physiol , vol.274
    • Malide, D.1    Davies-Hill, T.M.2    Levine, M.3    Simpson, I.A.4
  • 12
    • 0035856949 scopus 로고    scopus 로고
    • Insulin signalling and the regulation of glucose and lipid metabolism
    • DOI 10.1038/414799a
    • A. Saltiel, C R Kahn: Insulin signaling and the regulation of glucose and lipid metabolism. Nature 414, 799-806 (2001) (Pubitemid 34000783)
    • (2001) Nature , vol.414 , Issue.6865 , pp. 799-806
    • Saltiel, A.R.1    Kahn, C.R.2
  • 13
    • 0032987220 scopus 로고    scopus 로고
    • Insulin signalling: Metabolic pathways and mechanisms for specificity
    • DOI 10.1016/S0898-6568(99)00025-X, PII S089865689900025X
    • F. Nystrom, M J Quon: Insulin signaling: metabolic pathways and mechanisms for specificity. Cell Signal 11, 563-574 (1999) (Pubitemid 29255888)
    • (1999) Cellular Signalling , vol.11 , Issue.8 , pp. 563-574
    • Nystrom, F.H.1    Quon, M.2
  • 15
    • 14544271905 scopus 로고    scopus 로고
    • Positive and negative regulation of insulin signaling through IRS-1 phosphorylation
    • DOI 10.1016/j.biochi.2004.10.019
    • P Gual. Y Le Marchand-Brustel, J F Tanti: Positive and negative regulation of insulin signaling through IRS-1 phosphorylation. Biochimie 87, 99-109 (2005) (Pubitemid 40298772)
    • (2005) Biochimie , vol.87 , Issue.1 SPEC. ISSUE , pp. 99-109
    • Gual, P.1    Le Marchand-Brustel, Y.2    Tanti, J.-F.3
  • 16
    • 0037135547 scopus 로고    scopus 로고
    • In vivo phosphorylation of insulin receptor substrate 1 at serine 789 by a novel serine kinase in insulin-resistant rodents
    • DOI 10.1074/jbc.M201494200
    • L. Qiao, R Zhande. T L Jetton, G Zhou, X J Sun: In vivo phosphorylation of insulin receptor substrate 1 at serine 789 by a novel serine kinase in insulin-resistant rodents. J Biol Chem 277, 26530-26539 (2002) (Pubitemid 34967150)
    • (2002) Journal of Biological Chemistry , vol.277 , Issue.29 , pp. 26530-26539
    • Qiao, L.-Y.1    Zhande, R.2    Jetton, T.L.3    Zhou, G.4    Sun, X.J.5
  • 17
    • 0032143284 scopus 로고    scopus 로고
    • Phosphoinositide 3-kinase: The key switch mechanism in insulin signalling
    • P. Shepherd, D. Withers, K Siddle: Phosphoinositide 3-kinase: the key switch mechanism in insulin signalling. Biochem J 333(Pt 3), 471-490 (1998) (Pubitemid 28398511)
    • (1998) Biochemical Journal , vol.333 , Issue.3 , pp. 471-490
    • Shepherd, P.R.1    Withers, D.J.2    Siddle, K.3
  • 18
    • 0037205048 scopus 로고    scopus 로고
    • The phosphoinositide 3-kinase pathway
    • DOI 10.1126/science.296.5573.1655
    • L C Cantley: The phosphoinositide 3-kinase pathway. Science 296, 1655-1657 (2002) (Pubitemid 34579158)
    • (2002) Science , vol.296 , Issue.5573 , pp. 1655-1657
    • Cantley, L.C.1
  • 19
    • 0034653608 scopus 로고    scopus 로고
    • The PI3K-PBK1 connection: More than just a road to PKB
    • DOI 10.1042/0264-6021:3460561
    • B Vanhaesebroeck, D R Alessi: The PI3K-PDK1 connection: more than just a road to PKB. Biochem J 346 Pt 3, 561-576 (2000) (Pubitemid 30171014)
    • (2000) Biochemical Journal , vol.346 , Issue.3 , pp. 561-576
    • Vanhaesebroeck, B.1    Alessi, D.R.2
  • 20
    • 34047129136 scopus 로고    scopus 로고
    • Mek1/2 MAPK kinases are essential for mammalian development, homeostasis, and raf-induced hyperplasia
    • DOI 10.1016/j.devcel.2007.03.009, PII S1534580707001098
    • F. Scholl, P. Dumesic, D. Barragan, K Harada. V Bissonauth, J Charron, P A Khavari: Mek1/2 MAPK kinases are essential for Mammalian development, homeostasis, and Raf-induced hyperplasia. Dev Cell 12, 615-629 (2007) (Pubitemid 46523646)
    • (2007) Developmental Cell , vol.12 , Issue.4 , pp. 615-629
    • Scholl, F.A.1    Dumesic, P.A.2    Barragan, D.I.3    Harada, K.4    Bissonauth, V.5    Charron, J.6    Khavari, P.A.7
  • 21
    • 0037032817 scopus 로고    scopus 로고
    • Mitogen-activated protein kinase pathways mediated by ERK, JNK, and p38 protein kinases
    • DOI 10.1126/science.1072682
    • G. Johnson, R Lapadat: Mitogen-activated protein kinase pathways mediated by ERK, JNK, and p38 protein kinases. Science 298, 1911-1912 (2002) (Pubitemid 35425238)
    • (2002) Science , vol.298 , Issue.5600 , pp. 1911-1912
    • Johnson, G.L.1    Lapadat, R.2
  • 22
    • 67749117934 scopus 로고    scopus 로고
    • Signal integration by JNK and p38 MAPK pathways in cancer development
    • E. Wagner, A R Nebreda: Signal integration by JNK and p38 MAPK pathways in cancer development. Nat Rev Cancer 9, 537-549 (2009)
    • (2009) Nat Rev Cancer , vol.9 , pp. 537-549
    • Wagner, E.1    Nebreda, A.R.2
  • 23
    • 0142026209 scopus 로고    scopus 로고
    • P38 MAP kinases: Key signalling molecules as therapeutic targets for inflammatory diseases
    • S Kumar. J Boehm, J C Lee: p38 MAP kinases: key signalling molecules as therapeutic targets for inflammatory diseases. Nat Rev Drug Discov 2, 717-726 (2003) (Pubitemid 37361787)
    • (2003) Nature Reviews Drug Discovery , vol.2 , Issue.9 , pp. 717-726
    • Kumar, S.1    Boehm, J.2    Lee, J.C.3
  • 24
    • 0344081177 scopus 로고    scopus 로고
    • Minireview: The AMP-activated protein kinase cascade: The key sensor of cellular energy status
    • DOI 10.1210/en.2003-0982
    • D G Hardie: Minireview: the AMP-activated protein kinase cascade: the key sensor of cellular energy status. Endocrinology 144, 5179-5183 (2003) (Pubitemid 37476044)
    • (2003) Endocrinology , vol.144 , Issue.12 , pp. 5179-5183
    • Hardie, D.G.1
  • 25
    • 0242581695 scopus 로고    scopus 로고
    • Adiponectin stimulates production of nitric oxide in vascular endothelial cells
    • H Chen. M Montagnani, T Funahashi. I Shimomura, M J Quon: Adiponectin stimulates production of nitric oxide in vascular endothelial cells. J Biol Chem 278, 45021-450216 (2003)
    • (2003) J Biol Chem , vol.278 , pp. 45021-450216
    • Chen, H.1    Montagnani, M.2    Funahashi, T.3    Shimomura, I.4    Quon, M.J.5
  • 26
    • 0037379283 scopus 로고    scopus 로고
    • Effects of AICAR and exercise on insulin-stimulated glucose uptake, signaling, and GLUT-4 content in rat muscles
    • N Jessen. R Pold, E. Buhl, L. Jensen, O Schmitz, S Lund: Effects of AICAR and exercise on insulin-stimulated glucose uptake, signaling, and GLUT-4 content in rat muscles. J Appl Physiol 94, 1373-1379 (2003) (Pubitemid 36348812)
    • (2003) Journal of Applied Physiology , vol.94 , Issue.4 , pp. 1373-1379
    • Jessen, N.1    Pold, R.2    Buhl, E.S.3    Jensen, L.S.4    Schmitz, O.5    Lund, S.6
  • 27
    • 56449117024 scopus 로고    scopus 로고
    • AMPK: A metabolic gauge regulating whole-body energy homeostasis
    • R Lage. C Dieguez, A Vidal-Puig, M Lopez: AMPK: a metabolic gauge regulating whole-body energy homeostasis. Trends Mol Med 14, 539-549 (2008)
    • (2008) Trends Mol Med , vol.14 , pp. 539-549
    • Lage, R.1    Dieguez, C.2    Vidal-Puig, A.3    Lopez, M.4
  • 29
    • 9444242665 scopus 로고    scopus 로고
    • Five of stages of evolving β-cell dysfunction during progression to diabetes
    • DOI 10.2337/diabetes.53.suppl-3.S16
    • G. Weir, S Bonner-Weir: Five stages of evolving beta-cell dysfunction during progression to diabetes. Diabetes 53, Suppl 3, S16-21 (2004) (Pubitemid 39564517)
    • (2004) Diabetes , vol.53 , Issue.SUPPL. 3
    • Weir, G.C.1    Bonner-Weir, S.2
  • 31
    • 0033524937 scopus 로고    scopus 로고
    • Tissue-specific knockout of the insulin receptor in pancreatic β cells creates an insulin secretory defect similar to that in type 2 diabetes
    • DOI 10.1016/S0092-8674(00)80546-2
    • R. Kulkarni, J. Bruning, J. Winnay, C Postic. M A Magnuson, C R Kahn: Tissue-specific knockout of the insulin receptor in pancreatic beta cells creates an insulin secretory defect similar to that in type 2 diabetes. Cell 96, 329-339 (1999) (Pubitemid 29077587)
    • (1999) Cell , vol.96 , Issue.3 , pp. 329-339
    • Kulkarni, R.N.1    Bruning, J.C.2    Winnay, J.N.3    Postic, C.4    Magnuson, M.A.5    Ronald Kahn, C.6
  • 33
    • 33845866857 scopus 로고    scopus 로고
    • Inflammation and metabolic disorders
    • DOI 10.1038/nature05485, PII NATURE05485
    • G S Hotamisligil: Inflammation and metabolic disorders. Nature 444, 860-867 (2006) (Pubitemid 46024993)
    • (2006) Nature , vol.444 , Issue.7121 , pp. 860-867
    • Hotamisligil, G.S.1
  • 34
    • 2342517248 scopus 로고    scopus 로고
    • Role of oxidative stress in pancreatic β-cell dysfunction
    • DOI 10.1196/annals.1293.017
    • Y Kajimoto, H Kaneto: Role of oxidative stress in pancreatic beta-cell dysfunction. Ann N Y Acad Sci 1011, 168-176 (2004) (Pubitemid 38608402)
    • (2004) Annals of the New York Academy of Sciences , vol.1011 , pp. 168-176
    • Kajimoto, Y.1    Kaneto, H.2
  • 37
    • 3042825017 scopus 로고    scopus 로고
    • + channel 6.2 (SUR/Kir6.2) selective potassium channel opener in human islet
    • DOI 10.2337/diabetes.53.7.1706
    • K Maedler. J Storling, J Sturis. R A Zuellig, G. Spinas, P. Arkhammar, T Mandrup-Poulsen, M Y Donath: Glucoseand interleukin-1beta-induced beta-cell apoptosis requires Ca2+ influx and extracellular signal-regulated kinase (ERK) 1/2 activation and is prevented by a sulfonylurea receptor 1/inwardly rectifying K+ channel 6.2 (SUR/Kir6.2) selective potassium channel opener in human islets. Diabetes 53, 1706-1713 (2004) (Pubitemid 38857028)
    • (2004) Diabetes , vol.53 , Issue.7 , pp. 1706-1713
    • Maedler, K.1    Storling, J.2    Sturis, J.3    Zuellig, R.A.4    Spinas, G.A.5    Arkhammar, P.O.G.6    Mandrup-Poulsen, T.7    Donath, M.Y.8
  • 38
    • 0033034807 scopus 로고    scopus 로고
    • Hyperglycemia-induced β-cell apoptosis in pancreatic islets of Psammomys obesus during development of diabetes
    • M. Donath, D. Gross, E Cerasi, N Kaiser: Hyperglycemia-induced beta-cell apoptosis in pancreatic islets of Psammomys obesus during development of diabetes. Diabetes 48, 738-744 (1999) (Pubitemid 29153072)
    • (1999) Diabetes , vol.48 , Issue.4 , pp. 738-744
    • Donath, M.Y.1    Gross, D.J.2    Cerasi, E.3    Kaiser, N.4
  • 40
    • 0037219411 scopus 로고    scopus 로고
    • β-cell deficit and increased β-cell apoptosis in humans with type 2 diabetes
    • DOI 10.2337/diabetes.52.1.102
    • A. Butler, J Janson. S Bonner-Weir, R Ritzel. R A Rizza, P C Butler: Beta-cell deficit and increased beta-cell apoptosis in humans with type 2 diabetes. Diabetes 52, 102-110 (2003) (Pubitemid 36042113)
    • (2003) Diabetes , vol.52 , Issue.1 , pp. 102-110
    • Butler, A.E.1    Janson, J.2    Bonner-Weir, S.3    Ritzel, R.4    Rizza, R.A.5    Butler, P.C.6
  • 42
    • 0036315888 scopus 로고    scopus 로고
    • Prolonged exposure to free fatty acids has cytostatic and pro-apoptotic effects on human pancreatic islets: Evidence that β-cell death is caspase mediated, partially dependent on ceramide pathway, and Bcl-2 regulated
    • R Lupi. F Dotta, L Marselli. S Del Guerra, M Masini. C Santangelo, G Patane. U Boggi, S Piro. M Anello, E Bergamini. F Mosca, U D. Mario, S De. Prato, P Marchetti: Prolonged exposure to free fatty acids has cytostatic and proapoptotic effects on human pancreatic islets: evidence that beta-cell death is caspase mediated, partially dependent on ceramide pathway, and Bcl-2 regulated. Diabetes 51, 1437-1442 (2002) (Pubitemid 34826609)
    • (2002) Diabetes , vol.51 , Issue.5 , pp. 1437-1442
    • Lupi, R.1    Dotta, F.2    Marselli, L.3    Del Guerra, S.4    Masini, M.5    Santangelo, C.6    Patane, G.7    Boggi, U.8    Piro, S.9    Anello, M.10    Bergamini, E.11    Mosca, F.12    Di Mario, U.13    Del Prato, S.14    Marchetti, P.15
  • 43
    • 33845881411 scopus 로고    scopus 로고
    • Mechanisms linking obesity to insulin resistance and type 2 diabetes
    • DOI 10.1038/nature05482, PII NATURE05482
    • S. Kahn, R. Hull, K M Utzschneider: Mechanisms linking obesity to insulin resistance and type 2 diabetes. Nature 444, 840-846 (2006) (Pubitemid 46024990)
    • (2006) Nature , vol.444 , Issue.7121 , pp. 840-846
    • Kahn, S.E.1    Hull, R.L.2    Utzschneider, K.M.3
  • 45
    • 10744231746 scopus 로고    scopus 로고
    • Nonglycemic effects of insulin
    • DOI 10.1016/S1098-3597(03)90061-5
    • H Yki-Jarvinen: Nonglycemic effects of insulin. Clin Cornerstone Suppl 4, S6-S12 (2003) (Pubitemid 38180825)
    • (2003) Clinical Cornerstone , vol.5 , Issue.SUPPL. 4
    • Yki-Jarvinen, H.1
  • 47
    • 1542285112 scopus 로고    scopus 로고
    • Modulation of insulin action
    • DOI 10.1007/s00125-003-1313-3
    • L Pirola. A M Johnston, E Van Obberghen: Modulation of insulin action. Diabetologia 47, 170-184 (2004) (Pubitemid 38315353)
    • (2004) Diabetologia , vol.47 , Issue.2 , pp. 170-184
    • Pirola, L.1    Johnston, A.M.2    Van Obberghen, E.3
  • 50
    • 9244220626 scopus 로고    scopus 로고
    • Gluconeogenesis and glycogenolysis in health and diabetes
    • G Boden: Gluconeogenesis and glycogenolysis in health and diabetes. J Investig Med 52, 375-378 (2004) (Pubitemid 39552606)
    • (2004) Journal of Investigative Medicine , vol.52 , Issue.6 , pp. 375-378
    • Boden, G.1
  • 53
    • 0034881391 scopus 로고    scopus 로고
    • The adipocyte-secreted protein Acrp30 enhances hepatic insulin action
    • DOI 10.1038/90992
    • A. Berg, T. Combs, X Du. M Brownlee, P E Scherer: The adipocyte-secreted protein Acrp30 enhances hepatic insulin action. Nat Med 7, 947-953 (2001) (Pubitemid 32756433)
    • (2001) Nature Medicine , vol.7 , Issue.8 , pp. 947-953
    • Berg, A.H.1    Combs, T.P.2    Du, X.3    Brownlee, M.4    Scherer, P.E.5
  • 54
    • 33646826006 scopus 로고    scopus 로고
    • Lipid and lipoprotein dysregulation in insulin resistant states
    • DOI 10.1016/j.cca.2005.12.026, PII S0009898106000027
    • R. Avramoglu, H Basciano, K Adeli: Lipid and lipoprotein dysregulation in insulin resistant states. Clin Chim Acta 368, 1-19 (2006) (Pubitemid 43776015)
    • (2006) Clinica Chimica Acta , vol.368 , Issue.1-2 , pp. 1-19
    • Avramoglu, R.K.1    Basciano, H.2    Adeli, K.3
  • 58
    • 0037143637 scopus 로고    scopus 로고
    • Impaired nitric oxide synthase pathway in diabetes mellitus: Role of asymmetric dimethylarginine and dimethylarginine dimethylaminohydrolase
    • DOI 10.1161/01.CIR.0000027109.14149.67
    • K. Lin, A Ito. T Asagami, P. Tsao, S Adimoolam. M Kimoto, H Tsuji. G M Reaven, J P Cooke: Impaired nitric oxide synthase pathway in diabetes mellitus: role of asymmetric dimethylarginine and dimethylarginine dimethylaminohydrolase. Circulation 106, 987-92 (2002) (Pubitemid 34925335)
    • (2002) Circulation , vol.106 , Issue.8 , pp. 987-992
    • Lin, K.Y.1    Ito, A.2    Asagami, T.3    Tsao, P.S.4    Adimoolam, S.5    Kimoto, M.6    Tsuji, H.7    Reaven, G.M.8    Cooke, J.P.9
  • 59
    • 0035180299 scopus 로고    scopus 로고
    • Hyperglycemia inhibits endothelial nitric oxide synthase activity by posttranslational modification at the Akt site
    • DOI 10.1172/JCI200111235
    • X. Du, D Edelstein. S Dimmeler, Q Ju. C Sui, M Brownlee: Hyperglycemia inhibits endothelial nitric oxide synthase activity by posttranslational modification at the Akt site. J Clin Invest 108, 1341-1348 (2001) (Pubitemid 33107762)
    • (2001) Journal of Clinical Investigation , vol.108 , Issue.9 , pp. 1341-1348
    • Du, X.L.1    Edelstein, D.2    Dimmeler, S.3    Ju, Q.4    Sui, C.5    Brownlee, M.6
  • 62
    • 20044376702 scopus 로고    scopus 로고
    • The pathobiology of diabetic complications: A unifying mechanism
    • DOI 10.2337/diabetes.54.6.1615
    • M Brownlee: The pathobiology of diabetic complications: a unifying mechanism. Diabetes 54, 1615-1625 (2005) (Pubitemid 40770750)
    • (2005) Diabetes , vol.54 , Issue.6 , pp. 1615-1625
    • Brownlee, M.1
  • 63
    • 33644873810 scopus 로고    scopus 로고
    • Hexosamines, insulin resistance, and the complications of diabetes: Current status
    • M G Buse: Hexosamines, insulin resistance, and the complications of diabetes: current status. Am J Physiol Endocrinol Metab 290, E1-E8 (2006)
    • (2006) Am J Physiol Endocrinol Metab , vol.290
    • Buse, M.G.1
  • 65
    • 0031831261 scopus 로고    scopus 로고
    • Constitutive nitric oxide synthase expression in retinal vascular endothelial cells is suppressed by high glucose and advanced glycation end products
    • DOI 10.2337/diabetes.47.6.945
    • U Chakravarthy. R G Hayes, A. Stitt, E McAuley, D B Archer: Constitutive nitric oxide synthase expression in retinal vascular endothelial cells is suppressed by high glucose and advanced glycation end products. Diabetes 47, 945-952 (1998) (Pubitemid 28255670)
    • (1998) Diabetes , vol.47 , Issue.6 , pp. 945-952
    • Chakravarthy, U.1    Hayes, R.G.2    Stitt, A.W.3    McAuley, E.4    Archer, D.B.5
  • 66
    • 33644698706 scopus 로고    scopus 로고
    • Identification of the major site of O-linked β-N-acetylglucosamine modification in the C terminus of insulin receptor substrate-1
    • DOI 10.1074/mcp.M500314-MCP200
    • L. Ball, M. Berkaw, M G Buse: Identification of the major site of O-linked beta-N-acetylglucosamine modification in the C terminus of insulin receptor substrate-1. Mol Cell Proteomics 5, 313-23 (2006) (Pubitemid 43329309)
    • (2006) Molecular and Cellular Proteomics , vol.5 , Issue.2 , pp. 313-323
    • Ball, L.E.1    Berkaw, M.N.2    Buse, M.G.3
  • 67
    • 0028784442 scopus 로고
    • Glucosamine induces insulin resistance in vivo by affecting GLUT 4 translocation in skeletal muscle. Implications for glucose toxicity
    • A. Baron, J. Zhu, J. Zhu, H Weldon. L Maianu, W T Garvey: Glucosamine induces insulin resistance in vivo by affecting GLUT 4 translocation in skeletal muscle. Implications for glucose toxicity. J Clin Invest 96, 2792-2801 (1995)
    • (1995) J Clin Invest , vol.96 , pp. 2792-2801
    • Baron, A.1    Zhu, J.2    Zhu, J.3    Weldon, H.4    Maianu, L.5    Garvey, W.T.6
  • 68
    • 0033765672 scopus 로고    scopus 로고
    • High glucose level and free fatty acid stimulate reactive oxygen species production through protein kinase C-dependent activation of NAD (P) H oxidase in cultured vascular cells
    • T Inoguchi. P Li, F Umeda. H Y Yu, M Kakimoto. M Imamura, T Aoki. T Etoh, T Hashimoto. M Naruse, H Sano. H Utsumi, H Nawata: High glucose level and free fatty acid stimulate reactive oxygen species production through protein kinase C-dependent activation of NAD (P) H oxidase in cultured vascular cells. Diabetes 49, 1939-1945 (2000)
    • (2000) Diabetes , vol.49 , pp. 1939-1945
    • Inoguchi, T.1    Li, P.2    Umeda, F.3    Yu, H.Y.4    Kakimoto, M.5    Imamura, M.6    Aoki, T.7    Etoh, T.8    Hashimoto, T.9    Naruse, M.10    Sano, H.11    Utsumi, H.12    Nawata, H.13
  • 69
    • 0034651949 scopus 로고    scopus 로고
    • Regulation of endothelial constitutive nitric oxide synthase gene expression in endothelial cells and in vivo: A specific vascular action of insulin
    • K Kuboki. Z Y Jiang, N Takahara. S W Ha, M Igarashi. T Yamauchi, E. Feener, T. Herbert, C. Rhodes, G L King: Regulation of endothelial constitutive nitric oxide synthase gene expression in endothelial cells and in vivo: a specific vascular action of insulin. Circulation 101, 676-6810 (2000)
    • (2000) Circulation , vol.101 , pp. 676-6810
    • Kuboki, K.1    Jiang, Z.Y.2    Takahara, N.3    Ha, S.W.4    Igarashi, M.5    Yamauchi, T.6    Feener, E.7    Herbert, T.8    Rhodes, C.9    King, G.L.10
  • 70
    • 8644267972 scopus 로고    scopus 로고
    • Hyperglycemia-induced oxidative stress in diabetic complications
    • DOI 10.1007/s00418-004-0678-9
    • G. King, M R Loeken: Hyperglycemia-induced oxidative stress in diabetic complications. Histochem Cell Biol 122, 333-338 (2004) (Pubitemid 39506591)
    • (2004) Histochemistry and Cell Biology , vol.122 , Issue.4 , pp. 333-338
    • King, G.L.1    Loeken, M.R.2
  • 71
    • 33746920337 scopus 로고    scopus 로고
    • Advanced glycation end products: Sparking the development of diabetic vascular injury
    • DOI 10.1161/CIRCULATIONAHA.106.621854, PII 0000301720060808000013
    • A Goldin. J A Beckman, A. Schmidt, M A Creager: Advanced glycation end products: sparking the development of diabetic vascular injury. Circulation 14, 597-605 (2006) (Pubitemid 44199649)
    • (2006) Circulation , vol.114 , Issue.6 , pp. 597-605
    • Goldin, A.1    Beckman, J.A.2    Schmidt, A.M.3    Creager, M.A.4
  • 72
    • 23844469794 scopus 로고    scopus 로고
    • Oxidative stress and stress signaling: Menace of diabetic cardiomyopathy
    • DOI 10.1111/j.1745-7254.2005.00146.x
    • L. Wold, A. Ceylan-Isik, J Ren: Oxidative stress and stress signaling: menace of diabetic cardiomyopathy. Acta Pharmacol Sin 26, 908-917 (2005) (Pubitemid 41153210)
    • (2005) Acta Pharmacologica Sinica , vol.26 , Issue.8 , pp. 908-917
    • Wold, L.E.1    Ceylan-Isik, A.F.2    Ren, J.3
  • 73
    • 0346850870 scopus 로고    scopus 로고
    • Human Glycated Albumin Affects Glucose Metabolism in L6 Skeletal Muscle Cells by Impairing Insulin-induced Insulin Receptor Substrate (IRS) Signaling through a Protein Kinase Cα-mediated Mechanism
    • DOI 10.1074/jbc.M301088200
    • C Miele. A Riboulet, M. Maitan, F Oriente. C Romano, P Formisano. J Giudicelli, F Beguinot, E Van Obberghen: Human glycated albumin affects glucose metabolism in L6 skeletal muscle cells by impairing insulin-induced insulin receptor substrate (IRS) signaling through a protein kinase C alpha-mediated mechanism. J Biol Chem 278, 47376-47387 (2003) (Pubitemid 37523177)
    • (2003) Journal of Biological Chemistry , vol.278 , Issue.48 , pp. 47376-47387
    • Miele, C.1    Riboulet, A.2    Maitan, M.A.3    Oriente, F.4    Romano, C.5    Formisano, P.6    Giudicelli, J.7    Beguinot, F.8    Van Obberghen, E.9
  • 75
    • 0344286498 scopus 로고    scopus 로고
    • Activation of receptor for advanced glycation end products: A mechanism for chronic vascular dysfunction in diabetic vasculopathy and atherosclerosis
    • A. Schmidt, S. Yan, J. Wautier, D Stern: Activation of receptor for advanced glycation end products: a mechanism for chronic vascular dysfunction in diabetic vasculopathy and atherosclerosis. Circ Res 84, 489-497 (1999) (Pubitemid 29138585)
    • (1999) Circulation Research , vol.84 , Issue.5 , pp. 489-497
    • Schmidt, A.M.1    Yan, S.D.2    Wautier, J.-L.3    Stern, D.4
  • 76
    • 0034681229 scopus 로고    scopus 로고
    • Regulation of endothelial nitric oxide synthase expression by albumin-derived advanced glycosylation end products
    • A Rojas. S Romay, D Gonzalez. B Herrera, R Delgado, K Otero: Regulation of endothelial nitric oxide synthase expression by albumin-derived advanced glycosylation end products. Circ Res 86, E50-E54 (2000)
    • (2000) Circ Res , vol.86
    • Rojas, A.1    Romay, S.2    Gonzalez, D.3    Herrera, B.4    Delgado, R.5    Otero, K.6
  • 78
    • 8844255630 scopus 로고    scopus 로고
    • Free fatty acids in obesity and type 2 diabetes: Defining their role in the development of insulin resistance and β-cell dysfunction
    • DOI 10.1046/j.1365-2362.32.s3.3.x
    • G Boden, G I Shulman: Free fatty acids in obesity and type 2 diabetes: defining their role in the development of insulin resistance and beta-cell dysfunction. Eur J Clin Invest 32 Suppl 3, 14-23 (2002) (Pubitemid 41704996)
    • (2002) European Journal of Clinical Investigation , vol.32 , Issue.SUPPL. 3 , pp. 14-23
    • Boden, G.1    Shulman, G.I.2
  • 79
    • 0033927667 scopus 로고    scopus 로고
    • Cellular mechanisms of insulin resistance
    • G I Shulman: Cellular mechanisms of insulin resistance. J Clin Invest 106, 171-176 (2000) (Pubitemid 30483118)
    • (2000) Journal of Clinical Investigation , vol.106 , Issue.2 , pp. 171-176
    • Shulman, G.I.1
  • 80
    • 37349119004 scopus 로고    scopus 로고
    • Metabolic consequences of hyperglycemia and insulin resistance
    • DOI 10.1016/S1098-3597(07)80019-6, PII S1098359707800196
    • P S Jellinger: Metabolic consequences of hyperglycemia and insulin resistance. Clin Cornerstone 8 Suppl 7, S30-S42 (2007) (Pubitemid 350301031)
    • (2007) Clinical Cornerstone , vol.8 , Issue.SUPPL. 7
    • Jellinger, P.S.1
  • 83
    • 33645509709 scopus 로고    scopus 로고
    • Insulin resistance reduces arterial prostacyclin synthase and eNOS activities by increasing endothelial fatty acid oxidation
    • X Du. D Edelstein, S Obici. N Higham, M. Zou, M Brownlee: Insulin resistance reduces arterial prostacyclin synthase and eNOS activities by increasing endothelial fatty acid oxidation. J Clin Invest 116, 1071-1080 (2006)
    • (2006) J Clin Invest , vol.116 , pp. 1071-1080
    • Du, X.1    Edelstein, D.2    Obici, S.3    Higham, N.4    Zou, M.5    Brownlee, M.6
  • 84
    • 0037031893 scopus 로고    scopus 로고
    • Fatty acid infusion selectively impairs insulin action on Akt1 and protein kinase C lambda/zeta but not on glycogen synthase kinase-3
    • DOI 10.1074/jbc.M204710200
    • Y. Kim, G. Shulman, B B Kahn: Fatty acid infusion selectively impairs insulin action on Akt1 and protein kinase C lambda/zeta but not on glycogen synthase kinase-3. J Biol Chem 277, 32915-32922 (2002) (Pubitemid 34984805)
    • (2002) Journal of Biological Chemistry , vol.277 , Issue.36 , pp. 32915-32922
    • Kim, Y.-B.1    Shulman, G.I.2    Kahn, B.B.3
  • 89
    • 0033026734 scopus 로고    scopus 로고
    • Homocysteine and hypomethylation: A novel link to vascular disease
    • DOI 10.1016/S1050-1738(99)00002-X, PII S105017389900002X
    • M. Lee, H Wang: Homocysteine and Hypomethylation: A Novel Link to Vascular Disease. Trends in Cardiovascular Medicine 9, 49-54 (1999) (Pubitemid 29142580)
    • (1999) Trends in Cardiovascular Medicine , vol.9 , Issue.1-2 , pp. 49-54
    • Lee, M.-E.1    Wang, H.2
  • 92
    • 0032972277 scopus 로고    scopus 로고
    • Hyperhomocysteinemia is a risk factor for coronary arteriosclerosis in Japanese patients with type 2 diabetes
    • E Okada. K Oida, H Tada. K Asazuma, K Eguchi. G Tohda, S Kosaka. S Takahashi, I Miyamori: Hyperhomocysteinemia is a risk factor for coronary arteriosclerosis in Japanese patients with type 2 diabetes. Diabetes Care 22, 484-490 (1999) (Pubitemid 29106909)
    • (1999) Diabetes Care , vol.22 , Issue.3 , pp. 484-490
    • Okada, E.1    Oida, K.2    Tada, H.3    Asazuma, K.4    Eguchi, K.5    Tohda, G.6    Kosaka, S.7    Takahashi, S.8    Miyamori, I.9
  • 95
    • 0031854702 scopus 로고    scopus 로고
    • Insulin resistance is associated with elevated plasma total homocysteine levels in healthy, non-obese subjects
    • DOI 10.1016/S0021-9150(98)00067-7, PII S0021915098000677
    • E. Giltay, E. Hoogeveen, J. Elbers, L. Gooren, H Asscheman, C D Stehouwer: Insulin resistance is associated with elevated plasma total homocysteine levels in healthy, non-obese subjects. Atherosclerosis 139, 197-198 (1998) (Pubitemid 28341883)
    • (1998) Atherosclerosis , vol.139 , Issue.1 , pp. 197-198
    • Giltay, E.J.1    Hoogeveen, E.K.2    Elbers, J.M.H.3    Gooren, L.J.G.4    Asscheman, H.5    Stehouwer, C.D.A.6
  • 97
    • 0034882792 scopus 로고    scopus 로고
    • Homocysteine thiolactone inhibits insulin signaling, and glutathione has a protective effect
    • DOI 10.1677/jme.0.0270085
    • S Najib, V Sanchez-Margalet: Homocysteine thiolactone inhibits insulin signaling, and glutathione has a protective effect. J Mol Endocrinol 27, 85-91 (2001) (Pubitemid 32771460)
    • (2001) Journal of Molecular Endocrinology , vol.27 , Issue.1 , pp. 85-91
    • Najib, S.1    Sanchez-Margalet, V.2
  • 98
    • 14544296715 scopus 로고    scopus 로고
    • Homocysteine thiolactone inhibits insulin-stimulated DNA and protein synthesis: Possible role of mitogen-activated protein kinase (MAPK), glycogen synthase kinase-3 (GSK-3) and p70 S6K phosphorylation
    • DOI 10.1677/jme.1.01581
    • S Najib, V Sanchez-Margalet: Homocysteine thiolactone inhibits insulin-stimulated DNA and protein synthesis: possible role of mitogen-activated protein kinase (MAPK), glycogen synthase kinase-3 (GSK-3) and p70 S6K phosphorylation. J Mol Endocrinol 34, 119-126 (2005) (Pubitemid 40305554)
    • (2005) Journal of Molecular Endocrinology , vol.34 , Issue.1 , pp. 119-126
    • Najib, S.1    Sanchez-Margalet, V.2
  • 99
    • 0031737909 scopus 로고    scopus 로고
    • Effects of streptozotocin-induced diabetes and of insulin treatment on homocysteine metabolism in the rat
    • R. Jacobs, J. House, M. Brosnan, J T Brosnan: Effects of streptozotocin-induced diabetes and of insulin treatment on homocysteine metabolism in the rat. Diabetes 47, 1967-1970 (1998) (Pubitemid 28549207)
    • (1998) Diabetes , vol.47 , Issue.12 , pp. 1967-1970
    • Jacobs, R.L.1    House, J.D.2    Brosnan, M.E.3    Brosnan, J.T.4
  • 100
    • 0034813120 scopus 로고    scopus 로고
    • The effect of glucose and insulin on the activity of methylene tetrahydrofolate reductase and cystathionine-β-synthase: Studies in hepatocytes
    • DOI 10.1016/S0021-9150(01)00442-7, PII S0021915001004427
    • A Dicker-Brown. V A Fonseca, L. Fink, P A Kern: The effect of glucose and insulin on the activity of methylene tetrahydrofolate reductase and cystathionine-beta-synthase: studies in hepatocytes. Atherosclerosis 158, 297-301 (2001) (Pubitemid 32913638)
    • (2001) Atherosclerosis , vol.158 , Issue.2 , pp. 297-301
    • Dicker-Brown, A.1    Fonseca, V.A.2    Fink, L.M.3    Kern, P.A.4
  • 102
    • 0033552883 scopus 로고    scopus 로고
    • Atherosclerosis-an inflammatory disease
    • R Ross: Atherosclerosis-an inflammatory disease. N Engl J Med 340, 115-126 (1999)
    • (1999) N Engl J Med , vol.340 , pp. 115-126
    • Ross, R.1
  • 104
    • 0034527580 scopus 로고    scopus 로고
    • Insulin action in vascular endothelium: Potential mechanisms linking insulin resistance with hypertension
    • DOI 10.1046/j.1463-1326.2000.00092.x
    • M Montagnani, M J Quon: Insulin action in vascular endothelium: potential mechanisms linking insulin resistance with hypertension. Diabetes Obes Metab 2, 285-292 (2000) (Pubitemid 33072197)
    • (2000) Diabetes, Obesity and Metabolism , vol.2 , Issue.5 , pp. 285-292
    • Montagnani, M.1    Quon, M.J.2
  • 105
    • 0034603858 scopus 로고    scopus 로고
    • Roles for insulin receptor, PI3-kinase, and Akt in insulin-signaling pathways related to production of nitric oxide in human vascular endothelial cells
    • G Zeng. F H Nystrom, L. Ravichandran, L. Cong, M Kirby. H Mostowski, M J Quon: Roles for insulin receptor, PI3-kinase, and Akt in insulin-signaling pathways related to production of nitric oxide in human vascular endothelial cells. Circulation 101, 1539-1545 (2000) (Pubitemid 30180890)
    • (2000) Circulation , vol.101 , Issue.13 , pp. 1539-1545
    • Zeng, G.1    Nystrom, F.H.2    Ravichandran, L.V.3    Cong, L.-N.4    Kirby, M.5    Mostowski, H.6    Quon, M.J.7
  • 106
    • 0035839532 scopus 로고    scopus 로고
    • Insulinstimulated activation of eNOS is independent of Ca2+ but requires phosphorylation by Akt at Ser (1179)
    • M Montagnani. H Chen, V. Barr, M J Quon: Insulinstimulated activation of eNOS is independent of Ca2+ but requires phosphorylation by Akt at Ser (1179). J Biol Chem 276, 30392-30398 (2001)
    • (2001) J Biol Chem , vol.276 , pp. 30392-30398
    • Montagnani, M.1    Chen, H.2    Barr, V.3    Quon, M.J.4
  • 107
    • 13844296424 scopus 로고    scopus 로고
    • Insulin-stimulated endothelial nitric oxide release is calcium independent and mediated via protein kinase B
    • DOI 10.1016/j.bcp.2004.11.022
    • N. Hartell, H. Archer, C J Bailey: Insulin-stimulated endothelial nitric oxide release is calcium independent and mediated via protein kinase B. Biochem Pharmacol 69, 781-790 (2005) (Pubitemid 40248620)
    • (2005) Biochemical Pharmacology , vol.69 , Issue.5 , pp. 781-790
    • Hartell, N.A.1    Archer, H.E.2    Bailey, C.J.3
  • 108
    • 78149285435 scopus 로고    scopus 로고
    • Coronary and aortic endothelial function affected by feedback between adiponectin and tumor necrosis factor alpha in type 2 diabetic mice
    • H Zhang. Y Park, C Zhang: Coronary and aortic endothelial function affected by feedback between adiponectin and tumor necrosis factor alpha in type 2 diabetic mice. Arterioscler Thromb Vasc Biol 30, 2156-21563 (2010)
    • (2010) Arterioscler Thromb Vasc Biol , vol.30 , pp. 2156-21563
    • Zhang, H.1    Park, Y.2    Zhang, C.3
  • 109
    • 33748310586 scopus 로고    scopus 로고
    • Adiponectin suppression of high-glucoseinduced reactive oxygen species in vascular endothelial cells: Evidence for involvement of a cAMP signaling pathway
    • R Ouedraogo. X Wu, S. Xu, L Fuchsel. H Motoshima, K Mahadev. K Hough, R Scalia, B J Goldstein: Adiponectin suppression of high-glucoseinduced reactive oxygen species in vascular endothelial cells: evidence for involvement of a cAMP signaling pathway. Diabetes 55, 1840-18406 (2006)
    • (2006) Diabetes , vol.55 , pp. 1840-18406
    • Ouedraogo, R.1    Wu, X.2    Xu, S.3    Fuchsel, L.4    Motoshima, H.5    Mahadev, K.6    Hough, K.7    Scalia, R.8    Goldstein, B.J.9
  • 110
    • 62949133518 scopus 로고    scopus 로고
    • Molecular and clinical aspects of endothelial dysfunction in diabetes
    • C Nacci. M Tarquinio, M Montagnani: Molecular and clinical aspects of endothelial dysfunction in diabetes. Intern Emerg Med 4, 107-116 (2009)
    • (2009) Intern Emerg Med , vol.4 , pp. 107-116
    • Nacci, C.1    Tarquinio, M.2    Montagnani, M.3
  • 111
    • 0037900056 scopus 로고    scopus 로고
    • Pathophysiological implications of insulin resistance on vascular endothelial function
    • DOI 10.1046/j.1464-5491.2003.00869.x
    • S. Wheatcroft, I. Williams, A. Shah, M T Kearney: Pathophysiological implications of insulin resistance on vascular endothelial function. Diabet Med 20, 255-268 (2003) (Pubitemid 36606117)
    • (2003) Diabetic Medicine , vol.20 , Issue.4 , pp. 255-268
    • Wheatcroft, S.B.1    Williams, I.L.2    Shah, A.M.3    Kearney, M.T.4
  • 112
    • 33845516684 scopus 로고    scopus 로고
    • Treatment of spontaneously hypertensive rats with rosiglitazone and/or enalapril restores balance between vasodilator and vasoconstrictor actions of insulin with simultaneous improvement in hypertension and insulin resistance
    • M. Potenza, F. Marasciulo, M Tarquinio. M J Quon, M Montagnani: Treatment of spontaneously hypertensive rats with rosiglitazone and/or enalapril restores balance between vasodilator and vasoconstrictor actions of insulin with simultaneous improvement in hypertension and insulin resistance. Diabetes 55, 3594-35603 (2006)
    • (2006) Diabetes , vol.55 , pp. 3594-35603
    • Potenza, M.1    Marasciulo, F.2    Tarquinio, M.3    Quon, M.J.4    Montagnani, M.5
  • 116
    • 0020681210 scopus 로고
    • Differential responsiveness to insulin of endothelial and support cells from micro- and macrovessels
    • G. King, S. Buzney, C. Kahn, N Hetu. S Buchwald, S. Macdonald, L I Rand: Differential responsiveness to insulin of endothelial and support cells from micro-and macrovessels. J Clin Invest 71, 974-979 (1983) (Pubitemid 13163270)
    • (1983) Journal of Clinical Investigation , vol.71 , Issue.4 , pp. 974-979
    • King, G.L.1    Buzney, S.M.2    Kahn, C.R.3
  • 117
    • 0025894102 scopus 로고
    • Binding and biological effects of insulin, insulin analogues and insulin-like growth factors in rat aortic smooth muscle cells. Comparison of maximal growth promoting activities
    • K. Bornfeldt, R. Gidlof, A Wasteson. M Lake, A Skottner, H J Arnqvist: Binding and biological effects of insulin, insulin analogues and insulin-like growth factors in rat aortic smooth muscle cells. Comparison of maximal growth promoting activities. Diabetologia 34, 307-313 (1991)
    • (1991) Diabetologia , vol.34 , pp. 307-313
    • Bornfeldt, K.1    Gidlof, R.2    Wasteson, A.3    Lake, M.4    Skottner, A.5    Arnqvist, H.J.6
  • 118
    • 0021814480 scopus 로고
    • Characterization of the receptors for insulin and the insulin-like growth factors on micro- and macrovascular tissues
    • I Jialal. M Crettaz, H. Hachiya, C. Kahn, A. Moses, S. Buzney, G L King: Characterization of the receptors for insulin and the insulin-like growth factors on micro-and macrovascular tissues. Endocrinology 117, 1222-1229 (1985) (Pubitemid 15020055)
    • (1985) Endocrinology , vol.117 , Issue.3 , pp. 1222-1229
    • Jialal, I.1    Crettaz, M.2    Hachiya, H.L.3
  • 119
    • 0028014550 scopus 로고
    • Regulation of expression of glucose transporters by glucose: A review of studies in vivo and in cell cultures
    • A Klip. T Tsakiridis, A Marette, P A Ortiz: Regulation of expression of glucose transporters by glucose: a review of studies in vivo and in cell cultures. Faseb J 8, 43-53 (1994) (Pubitemid 24047410)
    • (1994) FASEB Journal , vol.8 , Issue.1 , pp. 43-53
    • Klip, A.1    Tsakiridis, T.2    Marette, A.3    Ortiz, P.A.4
  • 120
    • 0141866848 scopus 로고    scopus 로고
    • Insulin affects vascular smooth muscle cell phenotype and migration via distinct signaling pathways
    • DOI 10.2337/diabetes.52.10.2562
    • C. Wang, I Gurevich, B Draznin: Insulin affects vascular smooth muscle cell phenotype and migration via distinct signaling pathways. Diabetes 52, 2562-2569 (2003) (Pubitemid 37210546)
    • (2003) Diabetes , vol.52 , Issue.10 , pp. 2562-2569
    • Low Wang, C.C.1    Gurevich, I.2    Draznin, B.3
  • 121
    • 0030777901 scopus 로고    scopus 로고
    • Inhibition of MAP kinase blocks insulin-mediated DNA synthesis and transcriptional activation of c-fos by Elk-1 in vascular smooth muscle cells
    • DOI 10.1016/S0014-5793(97)01303-3, PII S0014579397013033
    • X. Xi, K Graf. S Goetze, W. Hsueh, R E Law: Inhibition of MAP kinase blocks insulin-mediated DNA synthesis and transcriptional activation of c-fos by Elk-1 in vascular smooth muscle cells. FEBS Lett 417, 283-286 (1997) (Pubitemid 27511605)
    • (1997) FEBS Letters , vol.417 , Issue.3 , pp. 283-286
    • Xi, X.-P.1    Graf, K.2    Goetze, S.3    Hsueh, W.A.4    Law, R.E.5
  • 122
    • 0032566624 scopus 로고    scopus 로고
    • Regulation of mitogen-activated protein kinase phosphatase-1 induction by insulin in vascular smooth muscle cells: Evaluation of the role of the nitric oxide signaling pathway and potential defects in hypertension
    • DOI 10.1074/jbc.273.39.25164
    • N Begum. L Ragolia, J Rienzie. M McCarthy, N Duddy: Regulation of mitogen-activated protein kinase phosphatase-1 induction by insulin in vascular smooth muscle cells. Evaluation of the role of the nitric oxide signaling pathway and potential defects in hypertension. J Biol Chem 273, 25164-25170 (1998) (Pubitemid 28443276)
    • (1998) Journal of Biological Chemistry , vol.273 , Issue.39 , pp. 25164-25170
    • Begum, N.1    Ragolia, L.2    Rienzie, J.3    McCarthy, M.4    Duddy, N.5
  • 123
    • 0032781886 scopus 로고    scopus 로고
    • Human vascular smooth muscle cells express a constitutive nitric oxide synthase that insulin rapidly activates, thus increasing guanosine 3': 5'- cyclic monophosphate and adenosine 3': 5'-cyclic monophosphate concentrations
    • DOI 10.1007/s001250051234
    • M Trovati. P Massucco, L Mattiello. C Costamagna, E Aldieri. F Cavalot, G Anfossi. A Bosia, D Ghigo: Human vascular smooth muscle cells express a constitutive nitric oxide synthase that insulin rapidly activates, thus increasing guanosine 3':5'-cyclic monophosphate and adenosine 3':5'-cyclic monophosphate concentrations. Diabetologia 42, 831-839 (1999) (Pubitemid 29325073)
    • (1999) Diabetologia , vol.42 , Issue.7 , pp. 831-839
    • Trovati, M.1    Massucco, P.2    Mattiello, L.3    Costamagna, C.4    Aldieri, E.5    Cavalot, F.6    Anfossi, G.7    Bosia, A.8    Ghigo, D.9
  • 124
    • 0029977757 scopus 로고    scopus 로고
    • Obesity/insulin resistance is associated with endothelial dysfunction. Implications for the syndrome of insulin resistance
    • H. Steinberg, H Chaker. R Leaming, A Johnson. G Brechtel, A D Baron: Obesity/insulin resistance is associated with endothelial dysfunction. Implications for the syndrome of insulin resistance. J Clin Invest 97, 2601-2610 (1996)
    • (1996) J Clin Invest , vol.97 , pp. 2601-2610
    • Steinberg, H.1    Chaker, H.2    Leaming, R.3    Johnson, A.4    Brechtel, G.5    Baron, A.D.6
  • 125
    • 77953393648 scopus 로고    scopus 로고
    • Endothelial dysfunction in diabetes mellitus: Molecular mechanisms and clinical implications
    • C. Tabit, W. Chung, N. Hamburg, J A Vita: Endothelial dysfunction in diabetes mellitus: molecular mechanisms and clinical implications. Rev Endocr Metab Disord 11, 61-74 (2010)
    • (2010) Rev Endocr Metab Disord , vol.11 , pp. 61-74
    • Tabit, C.1    Chung, W.2    Hamburg, N.3    Vita, J.A.4
  • 127
    • 33646178955 scopus 로고    scopus 로고
    • Reciprocal relationships between insulin resistance and endothelial dysfunction: Molecular and pathophysiological mechanisms
    • DOI 10.1161/CIRCULATIONAHA.105.563213, PII 0000301720060418000013
    • J. Kim, M Montagnani. K K Koh, M J Quon: Reciprocal relationships between insulin resistance and endothelial dysfunction: molecular and pathophysiological mechanisms. Circulation 113, 1888-1904 (2006) (Pubitemid 43739401)
    • (2006) Circulation , vol.113 , Issue.15 , pp. 1888-1904
    • Kim, J.-A.1    Montagnani, M.2    Kwang, K.K.3    Quon, M.J.4
  • 128
    • 0029119084 scopus 로고
    • Insulin-mediated skeletal muscle vasodilation contributes to both insulin sensitivity and responsiveness in lean humans
    • A. Baron, H. Steinberg, H Chaker. R Leaming, A Johnson, G Brechtel: Insulin-mediated skeletal muscle vasodilation contributes to both insulin sensitivity and responsiveness in lean humans. J Clin Invest 96, 786-792 (1995)
    • (1995) J Clin Invest , vol.96 , pp. 786-792
    • Baron, A.1    Steinberg, H.2    Chaker, H.3    Leaming, R.4    Johnson, A.5    Brechtel, G.6
  • 132
    • 0013054309 scopus 로고    scopus 로고
    • Mice with gene disruption of both endothelial and neuronal nitric oxide synthase exhibit insulin resistance
    • R. Shankar, Y Wu. H Q Shen, J. Zhu, A D Baron: Mice with gene disruption of both endothelial and neuronal nitric oxide synthase exhibit insulin resistance. Diabete 49, 684-687 (2000) (Pubitemid 30339980)
    • (2000) Diabetes , vol.49 , Issue.5 , pp. 684-687
    • Shankar, R.R.1    Wu, Y.2    Shen, H.-Q.3    Zhu, J.-S.4    Baron, A.D.5
  • 134
    • 7044247670 scopus 로고    scopus 로고
    • Activation of nulcear factor-kappaB by hyperglycemia in vascular smooth muscle cells is regulated by aldose reductase
    • DOI 10.2337/diabetes.53.11.2910
    • K. Ramana, B Friedrich. S Srivastava, A Bhatnagar, S K Srivastava: Activation of nuclear factor-kappaB by hyperglycemia in vascular smooth muscle cells is regulated by aldose reductase. Diabetes 53, 2910-2920 (2004) (Pubitemid 39425917)
    • (2004) Diabetes , vol.53 , Issue.11 , pp. 2910-2920
    • Ramana, K.V.1    Friedrich, B.2    Srivastava, S.3    Bhatnagar, A.4    Srivastava, S.K.5
  • 135
    • 0035078761 scopus 로고    scopus 로고
    • Diabetes accelerates smooth muscle accumulation in lesions of atherosclerosis: Lack of direct growth-promoting effects of high glucose levels
    • L. Suzuki, M Poot. R G Gerrity, K E Bornfeldt: Diabetes accelerates smooth muscle accumulation in lesions of atherosclerosis: lack of direct growth-promoting effects of high glucose levels. Diabetes 50, 851-860 (2001) (Pubitemid 32242644)
    • (2001) Diabetes , vol.50 , Issue.4 , pp. 851-860
    • Suzuki, L.A.1    Poot, M.2    Gerrity, R.G.3    Bornfeldt, K.E.4
  • 136
    • 0032233891 scopus 로고    scopus 로고
    • Immunohistochemical and morphometric evaluations of coronary atherosclerotic plaques associated with myocardial infarction and diabetes mellitus
    • H Fukumoto. Z Naito, G Asano, T Aramaki: Immunohistochemical and morphometric evaluations of coronary atherosclerotic plaques associated with myocardial infarction and diabetes mellitus. J Atheroscler Thromb 5, 29-35 (1998)
    • (1998) J Atheroscler Thromb , vol.5 , pp. 29-35
    • Fukumoto, H.1    Naito, Z.2    Asano, G.3    Aramaki, T.4
  • 138
  • 140
    • 0031012544 scopus 로고    scopus 로고
    • Insulin receptor substrate-2 is the major 170-kDa protein phosphorylated on tyrosine in response to cytokines in murine lymphohemopoietic cells
    • DOI 10.1074/jbc.272.2.1377
    • M. Welham, H Bone. M Levings, L Learmonth. L M Wang, K. Leslie, J. Pierce, J W Schrader: Insulin receptor substrate-2 is the major 170-kDa protein phosphorylated on tyrosine in response to cytokines in murine lymphohemopoietic cells. J Biol Chem 272, 1377-1381 (1997) (Pubitemid 27034643)
    • (1997) Journal of Biological Chemistry , vol.272 , Issue.2 , pp. 1377-1381
    • Welham, M.J.1    Bone, H.2    Levings, M.3    Learmonth, L.4    Wang, L.-M.5    Leslie, K.B.6    Pierce, J.H.7    Schrader, J.W.8
  • 141
    • 0017141749 scopus 로고
    • Fluctuations in the affinity and concentration of insulin receptors on circulating monocytes of obese patients: Effects of starvation, refeeding, and dieting
    • R. Bar, P Gorden. J Roth, C. Kahn, P De Meyts: Fluctuations in the affinity and concentration of insulin receptors on circulating monocytes of
    • (1976) J Clin Invest , vol.58 , pp. 1123-1135
    • Bar, R.1    Gorden, P.2    Roth, J.3    Kahn, C.4    De Meyts, P.5
  • 142
    • 0030055903 scopus 로고    scopus 로고
    • Apoptosis is abundant in human atherosclerotic lesions, especially in inflammatory cells (macrophages and T cells), and may contribute to the accumulation of gruel and plaque instability
    • S Bjorkerud, B Bjorkerud: Apoptosis is abundant in human atherosclerotic lesions, especially in inflammatory cells (macrophages and T cells), and may contribute to the accumulation of gruel and plaque instability. Am J Pathol 149, 367-380 (1996) (Pubitemid 26256326)
    • (1996) American Journal of Pathology , vol.149 , Issue.2 , pp. 367-380
    • Bjorkerud, S.1    Bjorkerud, B.2
  • 143
    • 0030639663 scopus 로고    scopus 로고
    • The presence of apoptotic cells in human atherosclerotic lesions
    • L Hegyi. S J Hardwick, M. Mitchinson, J N Skepper: The presence of apoptotic cells in human atherosclerotic lesions. Am J Pathol 150, 371-373 (1997)
    • (1997) Am J Pathol , vol.150 , pp. 371-373
    • Hegyi, L.1    Hardwick, S.J.2    Mitchinson, M.3    Skepper, J.N.4
  • 144
    • 0031858302 scopus 로고    scopus 로고
    • Apoptosis in atherogenesis: Implications for plaque destabilization
    • M. Kockx, A G Herman: Apoptosis in atherogenesis: implications for plaque destabilization. Eur Heart J 19 Suppl G, G23-G28 (1998) (Pubitemid 28321430)
    • (1998) European Heart Journal , vol.19 , Issue.SUPPL. G
    • Kockx, M.M.1    Herman, A.G.2
  • 146
    • 0021716062 scopus 로고
    • Acute regulation of human lymphocyte insulin receptors. Analysis by the glucose clamp
    • J H Helderman: Acute regulation of human lymphocyte insulin receptors. Analysis by the glucose clamp. J Clin Invest 74, 1428-1435 (1984)
    • (1984) J Clin Invest , vol.74 , pp. 1428-1435
    • Helderman, J.H.1
  • 147
    • 0346685840 scopus 로고    scopus 로고
    • + T lymphocytes
    • DOI 10.1016/j.metabol.2003.07.015
    • F. Stentz, A E Kitabchi: De novo emergence of growth factor receptors in activated human CD4+ and CD8+ T lymphocytes. Metabolism 53, 117-122 (2004) (Pubitemid 38071946)
    • (2004) Metabolism: Clinical and Experimental , vol.53 , Issue.1 , pp. 117-122
    • Stentz, F.B.1    Kitabchi, A.E.2
  • 148
    • 0019424525 scopus 로고
    • Role of insulin in the intermediary metabolism of the activated thymic-derived lymphocyte
    • J H Helderman: Role of insulin in the intermediary metabolism of the activated thymic-derived lymphocyte. J Clin Invest 67, 1636-1642 (1981) (Pubitemid 11127553)
    • (1981) Journal of Clinical Investigation , vol.67 , Issue.6 , pp. 1636-1642
    • Helderman, J.H.1
  • 149
    • 0026541710 scopus 로고
    • Evidence for recent as well as long term activation of T cells migrating through endothelial cell monolayers in vitro
    • J Masuyama. J S Berman, W. Cruikshank, C Morimoto, D M Center: Evidence for recent as well as long term activation of T cells migrating through endothelial cell monolayers in vitro. J Immunol 148, 1367-1374 (1992)
    • (1992) J Immunol , vol.148 , pp. 1367-1374
    • Masuyama, J.1    Berman, J.S.2    Cruikshank, W.3    Morimoto, C.4    Center, D.M.5
  • 150
    • 3042786038 scopus 로고    scopus 로고
    • C-peptide induces chemotaxis of human CD4-positive cells: Involvement of pertussis toxin-sensitive G-proteins and phosphoinositide 3-kinase
    • DOI 10.2337/diabetes.53.7.1664
    • D Walcher. M Aleksic, V Jerg. V Hombach, A Zieske. S Homma, J Strong, N Marx: C-peptide induces chemotaxis of human CD4-positive cells: involvement of pertussis toxin-sensitive G-proteins and phosphoinositide 3-kinase. Diabetes 53, 1664-1670 (2004) (Pubitemid 38857022)
    • (2004) Diabetes , vol.53 , Issue.7 , pp. 1664-1670
    • Walcher, D.1    Aleksic, M.2    Jerg, V.3    Hombach, V.4    Zieske, A.5    Homma, S.6    Strong, J.7    Marx, N.8
  • 153
    • 0031720795 scopus 로고    scopus 로고
    • Is type II diabetes mellitus a disease of the innate immune system?
    • DOI 10.1007/s001250051058
    • J. Pickup, M A Crook: Is type II diabetes mellitus a disease of the innate immune system? Diabetologia 41, 1241-1248 (1998) (Pubitemid 28449093)
    • (1998) Diabetologia , vol.41 , Issue.10 , pp. 1241-1248
    • Pickup, J.C.1    Crook, M.A.2
  • 154
    • 0034604248 scopus 로고    scopus 로고
    • Chronic subclinical inflammation as part of the insulin resistance syndrome: The insulin resistance atherosclerosis study (IRAS)
    • A Festa. R D'Agostino, Jr., G Howard. L Mykkanen, R. Tracy, S M Haffner: Chronic subclinical inflammation as part of the insulin resistance syndrome: the Insulin Resistance Atherosclerosis Study (IRAS). Circulation 102, 42-47 (2000) (Pubitemid 30430551)
    • (2000) Circulation , vol.102 , Issue.1 , pp. 42-47
    • Festa, A.1    D'Agostino Jr., R.2    Howard, G.3    Mykkanen, L.4    Tracy, R.P.5    Haffner, S.M.6
  • 155
    • 9144274444 scopus 로고    scopus 로고
    • Inflammation, insulin resistance, and atherosclerosis
    • DOI 10.1089/met.2004.2.105
    • P Theuma, V A Fonseca: Inflammation, insulin resistance, and atherosclerosis. Metab Syndr Relat Disord 2, 105-113 (2004) (Pubitemid 39545407)
    • (2004) Metabolic Syndrome and Related Disorders , vol.2 , Issue.2 , pp. 105-113
    • Theuma, P.1    Fonseca, V.A.2
  • 156
    • 52449110622 scopus 로고    scopus 로고
    • Macrophage function and its impact on atherosclerotic lesion composition, progression, and stability: The good, the bad, and the ugly
    • J. Dickhout, S Basseri, R C Austin: Macrophage function and its impact on atherosclerotic lesion composition, progression, and stability: the good, the bad, and the ugly. Arterioscler Thromb Vasc Biol 28, 1413-1415 (2008)
    • (2008) Arterioscler Thromb Vasc Biol , vol.28 , pp. 1413-1415
    • Dickhout, J.1    Basseri, S.2    Austin, R.C.3
  • 157
    • 0037180771 scopus 로고    scopus 로고
    • Inflammation in atherosclerosis
    • DOI 10.1038/nature01323
    • P Libby: Inflammation in atherosclerosis. Nature 420, 868-874 (2002) (Pubitemid 36019640)
    • (2002) Nature , vol.420 , Issue.6917 , pp. 868-874
    • Libby, P.1
  • 161
    • 0035026559 scopus 로고    scopus 로고
    • TNF-alpha inhibits flow and insulin signaling leading to NO production in aortic endothelial cells
    • F Kim. B Gallis, M A Corson: TNF-alpha inhibits flow and insulin signaling leading to NO production in aortic endothelial cells. Am J Physiol Cell Physiol 280, C1057-C1065 (2001)
    • (2001) Am J Physiol Cell Physiol , vol.280
    • Kim, F.1    Gallis, B.2    Corson, M.A.3
  • 163
    • 0028179224 scopus 로고
    • NFkappa B and I kappa B alpha: An inducible regulatory system in endothelial activation
    • M. Read, M. Whitley, A. Williams, T Collins: NFkappa B and I kappa B alpha: an inducible regulatory system in endothelial activation. J Exp Med 179, 503-512 (1994)
    • (1994) J Exp Med , vol.179 , pp. 503-512
    • Read, M.1    Whitley, M.2    Williams, A.3    Collins, T.4
  • 164
    • 0035979775 scopus 로고    scopus 로고
    • Reversal of obesity- and diet-induced insulin resistance with salicylates or targeted disruption of Ikkβ
    • DOI 10.1126/science.1061620
    • M Yuan. N Konstantopoulos, J Lee. L Hansen, Z. Li, M Karin, S E Shoelson: Reversal of obesity-and diet-induced insulin resistance with salicylates or targeted disruption of Ikkbeta. Science 293, 1673-1677 (2001) (Pubitemid 32807849)
    • (2001) Science , vol.293 , Issue.5535 , pp. 1673-1677
    • Yuan, M.1    Konstantopoulos, N.2    Lee, J.3    Hansen, L.4    Li, Z.-W.5    Karin, M.6    Shoelson, S.E.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.