Cerebral metabolic and cognitive decline in persons at genetic risk for Alzheimer's disease

Proceedings of the National Academy of Sciences of the United States of America

Volumn 97, Issue 11, 2000, Pages 6037-6042

  Small, Gary W ^a   Ercoli, Linda M ^a   Silverman, Daniel H S ^b   Huang, S C ^b   Komo, Scott ^a   Bookheimer, Susan Y ^a,c   Lavretsky, Helen ^a   Miller, Karen ^a   Siddarth, Prabha ^a   Rasgon, Natalie L ^a   Mazziotta, John C ^b,c   Saxena, Sanjaya ^a   Wu, H M ^b   Mega, Michael S ^b   Cummings, Jeffrey L ^a,b   Saunders, Ann M ^d   Pericak Vance, Margaret A ^d   Roses, Allen D ^d,e   Barrio, Jorge R ^b   Phelps, Michael E ^b  

^a Neuropsychiatric Institute   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d DUKE UNIVERSITY MEDICAL CENTER   (United States)

^e GLAXOSMITHKLINE   (United States)

Author keywords

Age associated memory impairment; Apolipoprotein E; Cerebral glucose metabolism; Positron emission tomography

Indexed keywords

APOLIPOPROTEIN E4; GLUCOSE;

ADULT; AGED; ALZHEIMER DISEASE; ARTICLE; BRAIN METABOLISM; CINGULATE GYRUS; COGNITIVE DEFECT; CONTROLLED STUDY; FEMALE; FOLLOW UP; GENETIC RISK; GLUCOSE BRAIN LEVEL; HETEROZYGOTE; HUMAN; MAJOR CLINICAL STUDY; MALE; MEMORY; PARIETAL LOBE; POSITRON EMISSION TOMOGRAPHY; PRIORITY JOURNAL; TEMPORAL CORTEX;

AGED; AGED, 80 AND OVER; ALLELES; ALZHEIMER DISEASE; APOLIPOPROTEIN E4; APOLIPOPROTEINS E; BRAIN; COGNITION DISORDERS; FEMALE; FOLLOW-UP STUDIES; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; HUMANS; MALE; MEMORY DISORDERS; MIDDLE AGED; PSYCHOLOGICAL TESTS; RISK FACTORS; TOMOGRAPHY, EMISSION-COMPUTED;

EID: 12944259210     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.090106797     Document Type: Article

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