메뉴 건너뛰기




Volumn 346, Issue 1, 2010, Pages 245-265

The neurodevelopmental implications of PI3K signaling

Author keywords

[No Author keywords available]

Indexed keywords

GROWTH FACTOR; PHOSPHATIDYLINOSITOL 3 KINASE;

EID: 79952114000     PISSN: 0070217X     EISSN: None     Source Type: Book Series    
DOI: 10.1007/82-2010-82     Document Type: Article
Times cited : (60)

References (148)
  • 2
    • 42349095075 scopus 로고    scopus 로고
    • Advances in autism genetics: On the threshold of a new neurobiology
    • DOI 10.1038/nrg2346, PII NRG2346
    • Abrahams BS, Geschwind DH (2008) Advances in autism genetics: on the threshold of a new neurobiology. Nat Rev Genet 9:341-355 (Pubitemid 351556064)
    • (2008) Nature Reviews Genetics , vol.9 , Issue.5 , pp. 341-355
    • Abrahams, B.S.1    Geschwind, D.H.2
  • 3
    • 69249124251 scopus 로고    scopus 로고
    • Male-biased effects of gonadotropin-releasing hormone neuron-specific deletion of the phosphoinositide 3-kinase regulatory subunit p85{alpha} on the reproductive axis
    • Acosta-Martinez M, Luo J, Elias C, Wolfe A, Levine JE (2009) Male-biased effects of gonadotropin-releasing hormone neuron-specific deletion of the phosphoinositide 3-kinase regulatory subunit p85{alpha} on the reproductive axis. Endocrinology 150:4203-4212
    • (2009) Endocrinology , vol.150 , pp. 4203-4212
    • Acosta-Martinez, M.1    Luo, J.2    Elias, C.3    Wolfe, A.4    Levine, J.E.5
  • 4
    • 33645362213 scopus 로고    scopus 로고
    • UNC-6/Netrin induces neuronal asymmetry and defines the site of axon formation
    • Adler CE, Fetter RD, Bargmann CI (2006) UNC-6/Netrin induces neuronal asymmetry and defines the site of axon formation. Nat Neurosci 9:511-518
    • (2006) Nat Neurosci , vol.9 , pp. 511-518
    • Adler, C.E.1    Fetter, R.D.2    Bargmann, C.I.3
  • 5
    • 0037384885 scopus 로고    scopus 로고
    • Stereological quantitation in cerebella from people with schizophrenia
    • DOI 10.1192/bjp.182.4.354
    • Andersen BB, Pakkenberg B (2003) Stereological quantitation in cerebella from people with schizophrenia. Br J Psychiatry 182:354-361 (Pubitemid 36408288)
    • (2003) British Journal of Psychiatry , vol.182 , Issue.APR. , pp. 354-361
    • Andersen, B.B.1    Pakkenberg, B.2
  • 6
    • 0029082109 scopus 로고
    • Symptoms, signs, and diagnosis of schizophrenia
    • Andreasen NC (1995) Symptoms, signs, and diagnosis of schizophrenia. Lancet 346:477-481
    • (1995) Lancet , vol.346 , pp. 477-481
    • Andreasen, N.C.1
  • 7
    • 33746581895 scopus 로고    scopus 로고
    • NTR inhibit glycogen synthase kinase-3β and stimulate axonal growth
    • DOI 10.1091/mbc.E05-12-1144
    • Arevalo MA, Rodriguez-Tebar A (2006) Activation of casein kinase II and inhibition of phosphatase and tensin homologue deleted on chromosome 10 phosphatase by nerve growth factor/ p75NTR inhibit glycogen synthase kinase-3beta and stimulate axonal growth. Mol Biol Cell 17:3369-3377 (Pubitemid 44156432)
    • (2006) Molecular Biology of the Cell , vol.17 , Issue.8 , pp. 3369-3377
    • Arevalo, M.-A.1    Rodriguez-Tebar, A.2
  • 8
    • 45749084834 scopus 로고    scopus 로고
    • A signaling pathway AKTing up in schizophrenia
    • DOI 10.1172/JCI35931
    • Arguello PA, Gogos JA (2008) A signaling pathway AKTing up in schizophrenia. J Clin Invest 118:2018-2021 (Pubitemid 351872321)
    • (2008) Journal of Clinical Investigation , vol.118 , Issue.6 , pp. 2018-2021
    • Arguello, P.A.1    Gogos, J.A.2
  • 9
    • 29144502438 scopus 로고    scopus 로고
    • Key regulators in neuronal polarity
    • DOI 10.1016/j.neuron.2005.11.007, PII S0896627305009475
    • Arimura N, Kaibuchi K (2005) Key regulators in neuronal polarity. Neuron 48:881-884 (Pubitemid 41814693)
    • (2005) Neuron , vol.48 , Issue.6 , pp. 881-884
    • Arimura, N.1    Kaibuchi, K.2
  • 11
    • 0042922829 scopus 로고    scopus 로고
    • Semaphorin 3F antagonizes neurotrophin-induced phosphatidylinositol 3-kinase and mitogen-activated protein kinase kinase signaling: A mechanism for growth cone collapse
    • Atwal JK, Singh KK, Tessier-Lavigne M, Miller FD, Kaplan DR (2003) Semaphorin 3F antagonizes neurotrophin-induced phosphatidylinositol 3-kinase and mitogen-activated protein kinase kinase signaling: a mechanism for growth cone collapse. J Neurosci 23:7602-7609 (Pubitemid 37034077)
    • (2003) Journal of Neuroscience , vol.23 , Issue.20 , pp. 7602-7609
    • Atwal, J.K.1    Singh, K.K.2    Tessier-Lavigne, M.3    Miller, F.D.4    Kaplan, D.R.5
  • 12
    • 33947583891 scopus 로고    scopus 로고
    • The Akt-GSK-3 signaling cascade in the actions of dopamine
    • DOI 10.1016/j.tips.2007.02.006, PII S0165614707000533
    • Beaulieu JM, Gainetdinov RR, Caron MG (2007) The Akt-GSK-3 signaling cascade in the actions of dopamine. Trends Pharmacol Sci 28:166-172 (Pubitemid 46483722)
    • (2007) Trends in Pharmacological Sciences , vol.28 , Issue.4 , pp. 166-172
    • Beaulieu, J.-M.1    Gainetdinov, R.R.2    Caron, M.G.3
  • 13
    • 0345894331 scopus 로고    scopus 로고
    • Reelin-mediated signaling locally regulates protein kinase B/Akt and glycogen synthase kinase 3β
    • DOI 10.1074/jbc.M209205200
    • Beffert U, Morfini G, Bock HH, Reyna H, Brady ST, Herz J (2002) Reelin-mediated signaling locally regulates protein kinase B/Akt and glycogen synthase kinase 3b. J Biol Chem 277:49958-49964 (Pubitemid 36014446)
    • (2002) Journal of Biological Chemistry , vol.277 , Issue.51 , pp. 49958-49964
    • Beffert, U.1    Morfini, G.2    Bock, H.H.3    Reyna, H.4    Brady, S.T.5    Herz, J.6
  • 14
    • 0141755223 scopus 로고    scopus 로고
    • Phosphatidylinositol 3-kinase interacts with the adaptor protein Dab1 in response to reelin signaling and is required for normal cortical lamination
    • DOI 10.1074/jbc.M306416200
    • Bock HH, Jossin Y, Liu P, Förster E, May P, Goffinet AM, Herz J (2003) Phosphatidylinositol 3-Kinase interacts with the adaptor protein Dab1 in response to Reelin signaling and is required for normal cortical lamination. J Biol Chem 278:38772-38779 (Pubitemid 37221776)
    • (2003) Journal of Biological Chemistry , vol.278 , Issue.40 , pp. 38772-38779
    • Bock, H.H.1    Jossin, Y.2    Liu, P.3    Forster, E.4    May, P.5    Goffinet, A.M.6    Herz, J.7
  • 18
    • 58149389019 scopus 로고    scopus 로고
    • Reelin stabilizes the actin cytoskeleton of neuronal processes by inducing n-cofilin phosphorylation at serine3
    • Chai X, Forster E, Zhao S, Bock HH, Frotscher M (2009) Reelin stabilizes the actin cytoskeleton of neuronal processes by inducing n-cofilin phosphorylation at serine3. J Neurosci 29:288-299
    • (2009) J Neurosci , vol.29 , pp. 288-299
    • Chai, X.1    Forster, E.2    Zhao, S.3    Bock, H.H.4    Frotscher, M.5
  • 19
    • 70350499765 scopus 로고    scopus 로고
    • Preview The Tortoise, the hare, and the FoxO
    • Chen E, Finkel T (2009) Preview. The Tortoise, the hare, and the FoxO. Cell Stem Cell 5:451-452
    • (2009) Cell Stem Cell , vol.5 , pp. 451-452
    • Chen, E.1    Finkel, T.2
  • 21
    • 34247174760 scopus 로고    scopus 로고
    • Phosphoinositide 3-kinase signalling events controlling axonal morphogenesis
    • DOI 10.1042/BST0350207
    • Cosker KE, Eickholt BJ (2007) Phosphoinositide 3-kinase signalling events controlling axonal morphogenesis. Biochem Soc Trans 35:207-210 (Pubitemid 46596469)
    • (2007) Biochemical Society Transactions , vol.35 , Issue.2 , pp. 207-210
    • Cosker, K.E.1    Eickholt, B.J.2
  • 22
    • 14644412928 scopus 로고    scopus 로고
    • Brain overgrowth in autism during a critical time in development: Implications for frontal pyramidal neuron and interneuron development and connectivity
    • DOI 10.1016/j.ijdevneu.2005.01.003
    • Courchesne E, Pierce K (2005) Brain overgrowth in autism during a critical time in development: implications for frontal pyramidal neuron and interneuron development and connectivity. Int J Dev Neurosci 23:153-170 (Pubitemid 40313549)
    • (2005) International Journal of Developmental Neuroscience , vol.23 , Issue.2-3 SPEC. ISS. , pp. 153-170
    • Courchesne, E.1    Pierce, K.2
  • 24
  • 27
    • 21244504231 scopus 로고    scopus 로고
    • Consensus clinical guidelines for the assessment of cognitive and behavioural problems in Tuberous Sclerosis
    • de Vries P, Humphrey A, McCartney D, Prather P, Bolton P, Hunt A (2005) Consensus clinical guidelines for the assessment of cognitive and behavioural problems in Tuberous Sclerosis. Eur Child Adolesc Psychiatry 14:183-190
    • (2005) Eur Child Adolesc Psychiatry , vol.14 , pp. 183-190
    • De Vries, P.1    Humphrey, A.2    McCartney, D.3    Prather, P.4    Bolton, P.5    Hunt, A.6
  • 28
    • 22344456913 scopus 로고    scopus 로고
    • Neuregulins rescue PC12-ErbB-4 cells from cell death induced by β-amyloid peptide: Involvement of PI3K and PKC
    • DOI 10.1385/JMN:26:03:57
    • Di Segni A, Shaharabani E, Stein R, Pinkas-Kramarski R (2005) Neuregulins rescue PC12-ErbB-4 cells from cell death induced by beta-amyloid peptide: involvement of PI3K and PKC. J Mol Neurosci 26:57-69 (Pubitemid 41003427)
    • (2005) Journal of Molecular Neuroscience , vol.26 , Issue.1 , pp. 57-69
    • Di Segni, A.1    Shaharabani, E.2    Stein, R.3    Pinkas-Kramarski, R.4
  • 29
    • 33750600736 scopus 로고    scopus 로고
    • ErbB4 activation inhibits MPP+-induced cell death in PC12-ErbB4 cells: Involvement of PI3K and Erk signaling
    • Di Segni A, Farin K, Pinkas-Kramarski R (2006) ErbB4 activation inhibits MPP+-induced cell death in PC12-ErbB4 cells: involvement of PI3K and Erk signaling. J Mol Neurosci 29:257-267
    • (2006) J Mol Neurosci , vol.29 , pp. 257-267
    • Di Segni, A.1    Farin, K.2    Pinkas-Kramarski, R.3
  • 32
    • 0037092042 scopus 로고    scopus 로고
    • An inactive pool of GSK-3 at the leading edge of growth cones is implicated in Semaphorin 3A signaling
    • DOI 10.1083/jcb.200201098
    • Eickholt BJ (2002) An inactive pool of GSK-3 at the leading edge of growth cones is implicated in Semaphorin 3A signaling. J Cell Biol 157:211-217 (Pubitemid 34839818)
    • (2002) Journal of Cell Biology , vol.157 , Issue.2 , pp. 211-217
    • Eickholt, B.J.1    Walsh, F.S.2    Doherty, P.3
  • 34
    • 0842310838 scopus 로고    scopus 로고
    • Convergent evidence for impaired AKT1-GSK3β signaling in schizophrenia
    • DOI 10.1038/ng1296
    • Emamian ES, Hall D, Birnbaum MJ, Karayiorgou M, Gogos JA (2004) Convergent evidence for impaired AKT1-GSK3[beta] signaling in schizophrenia. Nat Genet 36:131-137 (Pubitemid 38174370)
    • (2004) Nature Genetics , vol.36 , Issue.2 , pp. 131-137
    • Emamian, E.S.1    Hall, D.2    Birnbaum, M.J.3    Karayiorgou, M.4    Gogos, J.A.5
  • 35
    • 33746257209 scopus 로고    scopus 로고
    • The evolution of phosphatidylinositol 3-kinases as regulators of growth and metabolism
    • DOI 10.1038/nrg1879, PII NRG1879
    • Engelman JA, Luo J, Cantley LC (2006) The evolution of phosphatidylinositol 3-kinases as regulators of growth and metabolism. Nat Rev Genet 7:606-619 (Pubitemid 44100518)
    • (2006) Nature Reviews Genetics , vol.7 , Issue.8 , pp. 606-619
    • Engelman, J.A.1    Luo, J.2    Cantley, L.C.3
  • 37
    • 70349144020 scopus 로고    scopus 로고
    • Roles of disrupted-in-schizophrenia 1-interacting protein girdin in postnatal development of the dentate gyrus
    • Enomoto A, Asai N, Namba T, Wang Y, Kato T, Tanaka M, Tatsumi H, Taya S, Tsuboi D, Kuroda K et al (2009) Roles of disrupted-in-schizophrenia 1-interacting protein girdin in postnatal development of the dentate gyrus. Neuron 63:774-787
    • (2009) Neuron , vol.63 , pp. 774-787
    • Enomoto, A.1    Asai, N.2    Namba, T.3    Wang, Y.4    Kato, T.5    Tanaka, M.6    Tatsumi, H.7    Taya, S.8    Tsuboi, D.9    Kuroda, K.10
  • 38
    • 0026442248 scopus 로고
    • Cells expressing mRNA for neurotrophins and their receptors during embryonic rat development
    • Ernfors P, Merlio JP, Persson H (1992) Cells expressing mRNA for neurotrophins and their receptors during embryonic rat development. Eur J Neurosci 4:1140-1158
    • (1992) Eur J Neurosci , vol.4 , pp. 1140-1158
    • Ernfors, P.1    Merlio, J.P.2    Persson, H.3
  • 40
    • 46849090136 scopus 로고    scopus 로고
    • Robust neuronal symmetry breaking by Rastriggered local positive feedback
    • Fivaz M, Bandara S, Inoue T, Meyer T (2008) Robust neuronal symmetry breaking by Rastriggered local positive feedback. Curr Biol 18:44-50
    • (2008) Curr Biol , vol.18 , pp. 44-50
    • Fivaz, M.1    Bandara, S.2    Inoue, T.3    Meyer, T.4
  • 42
    • 37849027524 scopus 로고    scopus 로고
    • Phosphatase and tensin homolog, deleted on chromosome 10 deficiency in brain causes defects in synaptic structure, transmission and plasticity, and myelination abnormalities
    • Fraser MM, Bayazitov IT, Zakharenko SS, Baker SJ (2008) Phosphatase and tensin homolog, deleted on chromosome 10 deficiency in brain causes defects in synaptic structure, transmission and plasticity, and myelination abnormalities. Neuroscience 151:476-488
    • (2008) Neuroscience , vol.151 , pp. 476-488
    • Fraser, M.M.1    Bayazitov, I.T.2    Zakharenko, S.S.3    Baker, S.J.4
  • 44
    • 33748784602 scopus 로고    scopus 로고
    • RhoA-kinase coordinates F-actin organization and myosin II activity during semaphorin-3A-induced axon retraction
    • DOI 10.1242/jcs.03084
    • Gallo G (2006) RhoA-kinase coordinates F-actin organization and myosin II activity during semaphorin-3A-induced axon retraction. J Cell Sci 119:3413-3423 (Pubitemid 44405225)
    • (2006) Journal of Cell Science , vol.119 , Issue.16 , pp. 3413-3423
    • Gallo, G.1
  • 45
    • 44849097147 scopus 로고    scopus 로고
    • Semaphorin 3A inhibits ERM protein phosphorylation in growth cone filopodia through inactivation of PI3K
    • DOI 10.1002/dneu.20631
    • Gallo G (2008) Semaphorin 3A inhibits ERM protein phosphorylation in growth cone filopodia through inactivation of PI3K. Dev Neurobiol 68:926-933 (Pubitemid 351794112)
    • (2008) Developmental Neurobiology , vol.68 , Issue.7 , pp. 926-933
    • Gallo, G.1
  • 47
    • 70350417339 scopus 로고    scopus 로고
    • Cytoskeletal dynamics in growth-cone steering
    • Geraldo S, Gordon-Weeks PR (2009) Cytoskeletal dynamics in growth-cone steering. J Cell Sci 122:3595-3604
    • (2009) J Cell Sci , vol.122 , pp. 3595-3604
    • Geraldo, S.1    Gordon-Weeks, P.R.2
  • 48
    • 0033985644 scopus 로고    scopus 로고
    • Decreased dendritic spine density on prefrontal cortical pyramidal neurons in schizophrenia
    • Glantz LA, Lewis DA (2000) Decreased dendritic spine density on prefrontal cortical pyramidal neurons in schizophrenia. Arch Gen Psychiatry 57:65-73 (Pubitemid 30035660)
    • (2000) Archives of General Psychiatry , vol.57 , Issue.1 , pp. 65-73
    • Glantz, L.A.1    Lewis, D.A.2
  • 49
    • 29144436379 scopus 로고    scopus 로고
    • Apoptotic mechanisms and the synaptic pathology of schizophrenia
    • DOI 10.1016/j.schres.2005.08.014, PII S0920996405003683
    • Glantz LA, Gilmore JH, Lieberman JA, Jarskog LF (2006) Apoptotic mechanisms and the synaptic pathology of schizophrenia. Schizophr Res 81:47-63 (Pubitemid 41817206)
    • (2006) Schizophrenia Research , vol.81 , Issue.1 , pp. 47-63
    • Glantz, L.A.1    Gilmore, J.H.2    Lieberman, J.A.3    Jarskog, L.F.4
  • 52
    • 4944252817 scopus 로고    scopus 로고
    • Insulin-like growth factors, insulin resistance and schizophrenia [3]
    • Gunnell D, Holly JMP (2004) Insulin-like growth factors, insulin resistance and schizophrenia. Br J Psychiatry 185:353-354 (Pubitemid 39331341)
    • (2004) British Journal of Psychiatry , vol.185 , Issue.OCT. , pp. 353-354
    • Gunnell, D.1    Holly, J.M.P.2
  • 53
    • 34250013435 scopus 로고    scopus 로고
    • Role of the integrin-linked kinase (ILK) in determining neuronal polarity
    • DOI 10.1016/j.ydbio.2007.03.019, PII S0012160607002205
    • Guo W, Jiang H, Gray V, Dedhar S, Rao Y (2007) Role of the integrin-linked kinase (ILK) in determining neuronal polarity. Dev Biol 306:457-468 (Pubitemid 46881064)
    • (2007) Developmental Biology , vol.306 , Issue.2 , pp. 457-468
    • Guo, W.1    Jiang, H.2    Gray, V.3    Dedhar, S.4    Rao, Y.5
  • 55
    • 0033514084 scopus 로고    scopus 로고
    • Brains at risk of schizophrenia
    • Harrison PJ (1999) Brains at risk of schizophrenia. Lancet 353:3-4 (Pubitemid 29037690)
    • (1999) Lancet , vol.353 , Issue.9146 , pp. 3-4
    • Harrison, P.J.1
  • 56
    • 12144270390 scopus 로고    scopus 로고
    • Relationship of brain-derived neurotrophic factor and its receptor TrkB to altered inhibitory prefrontal circuitry in schizophrenia
    • DOI 10.1523/JNEUROSCI.4035-04.2005
    • Hashimoto T, Bergen SE, Nguyen QL, Xu B, Monteggia LM, Pierri JN, Sun Z, Sampson AR, Lewis DA (2005) Relationship of brain-derived neurotrophic factor and its receptor TrkB to altered inhibitory prefrontal circuitry in schizophrenia. J Neurosci 25:372-383 (Pubitemid 40105607)
    • (2005) Journal of Neuroscience , vol.25 , Issue.2 , pp. 372-383
    • Hashimoto, T.1    Bergen, S.E.2    Nguyen, Q.L.3    Xu, B.4    Monteggia, L.M.5    Pierri, J.N.6    Sun, Z.7    Sampson, A.R.8    Lewis, D.A.9
  • 57
    • 4043171462 scopus 로고    scopus 로고
    • Upstream and downstream of mTOR
    • DOI 10.1101/gad.1212704
    • Hay N, Sonenberg N (2004) Upstream and downstream of mTOR. Genes Dev 18:1926-1945 (Pubitemid 39071573)
    • (2004) Genes and Development , vol.18 , Issue.16 , pp. 1926-1945
    • Hay, N.1    Sonenberg, N.2
  • 58
    • 25144436404 scopus 로고    scopus 로고
    • Large brains in autism: The challenge of pervasive abnormality
    • DOI 10.1177/0091270005278866
    • Herbert MR (2005) Large brains in autism: the challenge of pervasive abnormality. Neuroscientist 11:417-440 (Pubitemid 41339228)
    • (2005) Neuroscientist , vol.11 , Issue.5 , pp. 417-440
    • Herbert, M.R.1
  • 60
    • 3242759878 scopus 로고    scopus 로고
    • Case-control and family-based association studies between the neuregulin 1 (Arg38Gln) polymorphism and schizophrenia
    • DOI 10.1016/j.neulet.2004.05.027, PII S030439400400607X
    • Hong CJ, Huo SJ, Liao DL, Lee K, Wu JY, Tsai SJ (2004) Case-control and family-based association studies between the neuregulin 1 (Arg38Gln) polymorphism and schizophrenia. Neurosci Lett 366:158-161 (Pubitemid 38970147)
    • (2004) Neuroscience Letters , vol.366 , Issue.2 , pp. 158-161
    • Hong, C.-J.1    Huo, S.-J.2    Liao, D.-L.3    Lee, K.4    Wu, J.-Y.5    Tsai, S.-J.6
  • 61
    • 33746639189 scopus 로고    scopus 로고
    • 3 by GAKIN, a kinesin-3 family protein, regulates neuronal cell polarity
    • DOI 10.1083/jcb.200604031
    • Horiguchi K, Hanada T, Fukui Y, Chishti AH (2006) Transport of PIP3 by GAKIN, a kinesin-3 cfamily protein, regulates neuronal cell polarity. J Cell Biol 174:425-436 (Pubitemid 44156772)
    • (2006) Journal of Cell Biology , vol.174 , Issue.3 , pp. 425-436
    • Horiguchi, K.1    Hanada, T.2    Fukui, Y.3    Chishti, A.H.4
  • 62
    • 0037895042 scopus 로고    scopus 로고
    • Region-specific mRNA expression of phosphatidylinositol 3-kinase regulatory isoforms in the central nervous system of C57BL/6J mice
    • DOI 10.1002/(SICI)1096-9861(19991206)415:1<105::AID-CNE8>3.0.CO;2-H
    • Hörsch D, Kahn CR (1999) Region-specific mRNA expression of phosphatidylinositol 3-kinase regulatory isoforms in the central nervous system of C57BL/6J mice. J Comp Neurol 415:105-120 (Pubitemid 29519889)
    • (1999) Journal of Comparative Neurology , vol.415 , Issue.1 , pp. 105-120
    • Horsch, D.1    Kahn, C.R.2
  • 63
    • 57149117828 scopus 로고    scopus 로고
    • A PI3-kinase-mediated negative feedback regulates neuronal excitability
    • Howlett E, Lin CC, Lavery W, SternM(2008) A PI3-kinase-mediated negative feedback regulates neuronal excitability. PLoS Genet 4:e1000277
    • (2008) PLoS Genet , vol.4
    • Howlett, E.1    Lin, C.C.2    Lavery, W.3    Stern, M.4
  • 64
    • 0036713778 scopus 로고    scopus 로고
    • TSC2 is phosphorylated and inhibited by Akt and suppresses mTOR signalling
    • DOI 10.1038/ncb839
    • Inoki K, Li Y, Zhu T, Wu J, Guan K-L (2002) TSC2 is phosphorylated and inhibited by Akt and suppresses mTOR signalling. Nat Cell Biol 4:648-657 (Pubitemid 34993700)
    • (2002) Nature Cell Biology , vol.4 , Issue.9 , pp. 648-657
    • Inoki, K.1    Li, Y.2    Zhu, T.3    Wu, J.4    Guan, K.-L.5
  • 65
    • 0028802890 scopus 로고
    • Localization of mRNA for phosphatidylinositol 3-kinase in brain of developing and mature rats
    • Ito Y, Goto K, Kondo H (1995) Localization of mRNA for phosphatidylinositol 3-kinase in brain of developing and mature rats. Brain Res Mol Brain Res 34:149-153
    • (1995) Brain Res Mol Brain Res , vol.34 , pp. 149-153
    • Ito, Y.1    Goto, K.2    Kondo, H.3
  • 66
    • 33745603987 scopus 로고    scopus 로고
    • Sema4D/plexin-B1 activates GSK-3β through R-Ras GAP activity, inducing growth cone collapse
    • DOI 10.1038/sj.embor.7400737, PII 7400737
    • Ito Y, Oinuma I, Katoh H, Kaibuchi K, NegishiM(2006) Sema4D/plexin-B1 activates GSK-3beta through R-Ras GAP activity, inducing growth cone collapse. EMBO Rep 7:704-709 (Pubitemid 43986267)
    • (2006) EMBO Reports , vol.7 , Issue.7 , pp. 704-709
    • Ito, Y.1    Oinuma, I.2    Katoh, H.3    Kaibuchi, K.4    Negishi, M.5
  • 67
    • 33749076673 scopus 로고    scopus 로고
    • SIN1/MIP1 Maintains rictor-mTOR Complex Integrity and Regulates Akt Phosphorylation and Substrate Specificity
    • DOI 10.1016/j.cell.2006.08.033, PII S0092867406011470
    • Jacinto E, Facchinetti V, Liu D, Soto N, Wei S, Jung SY, Huang Q, Qin J, Su B (2006) SIN1/MIP1 maintains rictor-mTOR complex integrity and regulates Akt phosphorylation and substrate specificity. Cell 127:125-137 (Pubitemid 44466632)
    • (2006) Cell , vol.127 , Issue.1 , pp. 125-137
    • Jacinto, E.1    Facchinetti, V.2    Liu, D.3    Soto, N.4    Wei, S.5    Jung, S.Y.6    Huang, Q.7    Qin, J.8    Su, B.9
  • 68
    • 0141918787 scopus 로고    scopus 로고
    • The control of dendrite development
    • DOI 10.1016/S0896-6273(03)00631-7
    • Jan YN, Jan LY (2003) The control of dendrite development. Neuron 40:229-242 (Pubitemid 37244094)
    • (2003) Neuron , vol.40 , Issue.2 , pp. 229-242
    • Jan, Y.-N.1    Jan, L.Y.2
  • 69
    • 30544449810 scopus 로고    scopus 로고
    • Control of dendritic arborization by the phosphoinositide-3'-kinase- Akt-mammalian target of rapamycin pathway
    • DOI 10.1523/JNEUROSCI.2270-05.2005
    • Jaworski J, Spangler S, Seeburg DP, Hoogenraad CC, Sheng M (2005) Control of dendritic arborization by the phosphoinositide-30-kinase-Akt-mammalian target of rapamycin pathway. J Neurosci 25:11300-11312 (Pubitemid 43083704)
    • (2005) Journal of Neuroscience , vol.25 , Issue.49 , pp. 11300-11312
    • Jaworski, J.1    Spangler, S.2    Seeburg, D.P.3    Hoogenraad, C.C.4    Sheng, M.5
  • 70
    • 35148880174 scopus 로고    scopus 로고
    • Reelin signals through phosphatidylinositol 3-kinase and Akt to control cortical development and through mTor to regulate dendritic growth
    • DOI 10.1128/MCB.00928-07
    • Jossin Y, Goffinet AM (2007) Reelin signals through phosphatidylinositol 3-kinase and Akt to control cortical development and through mTor to regulate dendritic growth. Mol Cell Biol 27:7113-7124 (Pubitemid 47549749)
    • (2007) Molecular and Cellular Biology , vol.27 , Issue.20 , pp. 7113-7124
    • Jossin, Y.1    Goffinet, A.M.2
  • 71
    • 32644480629 scopus 로고    scopus 로고
    • The role of the phosphatidylinositide 3-kinase-protein kinase B pathway in schizophrenia
    • DOI 10.1016/j.pharmthera.2005.10.014, PII S0163725805002779
    • Kalkman HO (2006) The role of the phosphatidylinositide 3-kinase-protein kinase B pathway in schizophrenia. Pharmacol Ther 110:117-134 (Pubitemid 43248729)
    • (2006) Pharmacology and Therapeutics , vol.110 , Issue.1 , pp. 117-134
    • Kalkman, H.O.1
  • 72
    • 0034626870 scopus 로고    scopus 로고
    • The dendritic architecture of prefrontal pyramidal neurons in schizophrenic patients
    • Kalus P, Muller TJ, Zuschratter W, Senitz D (2000) The dendritic architecture of prefrontal pyramidal neurons in schizophrenic patients. Neuroreport 11:3621-3625
    • (2000) Neuroreport , vol.11 , pp. 3621-3625
    • Kalus, P.1    Muller, T.J.2    Zuschratter, W.3    Senitz, D.4
  • 75
    • 70349130726 scopus 로고    scopus 로고
    • DISC1 regulates new neuron development in the adult brain via modulation of AKTmTOR signaling through KIAA1212
    • Kim JY, Duan X, Liu CY, Jang MH, Guo JU, Pow-anpongkul N, Kang E, Song H, Ming GL (2009) DISC1 regulates new neuron development in the adult brain via modulation of AKTmTOR signaling through KIAA1212. Neuron 63:761-773
    • (2009) Neuron , vol.63 , pp. 761-773
    • Kim, J.Y.1    Duan, X.2    Liu, C.Y.3    Jang, M.H.4    Guo, J.U.5    Pow-anpongkul, N.6    Kang, E.7    Song, H.8    Ming, G.L.9
  • 78
    • 77955293704 scopus 로고    scopus 로고
    • Regulation of PTEN in neurons by myosin-based transport mechanisms
    • Kreis P, van Diepen MT, Eickholt BJ (2009) Regulation of PTEN in neurons by myosin-based transport mechanisms. Adv Enzyme Regul 50:119-124
    • (2009) Adv Enzyme Regul , vol.50 , pp. 119-124
    • Kreis, P.1    Van Diepen, M.T.2    Eickholt, B.J.3
  • 79
    • 30544442753 scopus 로고    scopus 로고
    • Regulation of dendritic morphogenesis by Ras-PI3K-Akt-mTOR and Ras-MAPK signaling pathways
    • DOI 10.1523/JNEUROSCI.2284-05.2005
    • Kumar V, Zhang MX, Swank MW, Kunz J, Wu GY (2005) Regulation of dendritic morphogenesis by Ras-PI3K-Akt-mTOR and Ras-MAPK signaling pathways. J Neurosci 25:11288-11299 (Pubitemid 43083703)
    • (2005) Journal of Neuroscience , vol.25 , Issue.49 , pp. 11288-11299
    • Kumar, V.1    Zhang, M.-X.2    Swank, M.W.3    Kunz, J.4    Wu, G.-Y.5
  • 81
    • 33645767494 scopus 로고    scopus 로고
    • Neuron-specific enolase-cre mouse line with cre activity in specific neuronal populations
    • Kwon CH, Zhou J, Li Y, Kim KW, Hensley LL, Baker SJ, Parada LF (2006b) Neuron-specific enolase-cre mouse line with cre activity in specific neuronal populations. Genesis 44:130-135
    • (2006) Genesis , vol.44 , pp. 130-135
    • Kwon, C.H.1    Zhou, J.2    Li, Y.3    Kim, K.W.4    Hensley, L.L.5    Baker, S.J.6    Parada, L.F.7
  • 84
    • 65249140471 scopus 로고    scopus 로고
    • The genetic and neurobiologic compass points toward common signaling dysfunctions in autism spectrum disorders
    • Levitt P, Campbell DB (2009) The genetic and neurobiologic compass points toward common signaling dysfunctions in autism spectrum disorders. J Clin Invest 119:747-754
    • (2009) J Clin Invest , vol.119 , pp. 747-754
    • Levitt, P.1    Campbell, D.B.2
  • 88
    • 70449389118 scopus 로고    scopus 로고
    • Lack of association between AKT1 variances versus clinical manifestations and social function in patients with schizophrenia
    • Liu YC, Huang CL, Wu PL, Chang YC, Huang CH, Lane HY (2009) Lack of association between AKT1 variances versus clinical manifestations and social function in patients with schizophrenia. J Psychopharmacol 23:937-943
    • (2009) J Psychopharmacol , vol.23 , pp. 937-943
    • Liu, Y.C.1    Huang, C.L.2    Wu, P.L.3    Chang, Y.C.4    Huang, C.H.5    Lane, H.Y.6
  • 91
    • 62149083806 scopus 로고    scopus 로고
    • Disrupted in schizophrenia 1 regulates neuronal progenitor proliferation via modulation of GSK3beta/beta-catenin signaling
    • Mao Y, Ge X, Frank CL, Madison JM, Koehler AN, Doud MK, Tassa C, Berry EM, Soda T, Singh KK et al (2009) Disrupted in schizophrenia 1 regulates neuronal progenitor proliferation via modulation of GSK3beta/beta-catenin signaling. Cell 136:1017-1031
    • (2009) Cell , vol.136 , pp. 1017-1031
    • Mao, Y.1    Ge, X.2    Frank, C.L.3    Madison, J.M.4    Koehler, A.N.5    Doud, M.K.6    Tassa, C.7    Berry, E.M.8    Soda, T.9    Singh, K.K.10
  • 92
    • 27844479666 scopus 로고    scopus 로고
    • Macrocephaly and the control of brain growth in autistic disorders
    • DOI 10.1016/j.pneurobio.2005.10.005, PII S0301008205001188
    • McCaffery P, Deutsch CK (2005) Macrocephaly and the control of brain growth in autistic disorders. Prog Neurobiol 77:38-56 (Pubitemid 41654772)
    • (2005) Progress in Neurobiology , vol.77 , Issue.1-2 , pp. 38-56
    • McCaffery, P.1    Deutsch, C.K.2
  • 93
    • 6344265082 scopus 로고    scopus 로고
    • TrkB regulates neocortex formation through the Shc/PLCγ-mediated control of neuronal migration
    • DOI 10.1038/sj.emboj.7600399
    • Medina DL, Sciarretta C, Calella AM, von Bohlen und Halbach O, Unsicker K, Minichiello L (2004) TrkB regulates neocortex formation through the Shc/PLC[gamma]-mediated control of neuronal migration. EMBO J 23:3803-3814 (Pubitemid 39389711)
    • (2004) EMBO Journal , vol.23 , Issue.19 , pp. 3803-3814
    • Medina, D.L.1    Sciarretta, C.2    Calella, A.M.3    Von Bohlen Halbach, O.4    Unsicker, K.5    Minichiello, L.6
  • 94
    • 43949084738 scopus 로고    scopus 로고
    • Neuregulin 1 in neural development, synaptic plasticity and schizophrenia
    • DOI 10.1038/nrn2392, PII NRN2392
    • Mei L, Xiong WC (2008) Neuregulin 1 in neural development, synaptic plasticity and schizophrenia. Nat Rev Neurosci 9:437-452 (Pubitemid 351704944)
    • (2008) Nature Reviews Neuroscience , vol.9 , Issue.6 , pp. 437-452
    • Mei, L.1    Xiong, W.-C.2
  • 96
    • 62149100000 scopus 로고    scopus 로고
    • DISC1 partners with GSK3beta in neurogenesis
    • Ming GL, Song H (2009) DISC1 partners with GSK3beta in neurogenesis. Cell 136:990-992
    • (2009) Cell , vol.136 , pp. 990-992
    • Ming, G.L.1    Song, H.2
  • 97
    • 70350455151 scopus 로고    scopus 로고
    • Specification of neuronal polarity regulated by local translation of CRMP2 and Tau via the mTOR-p70S6K pathway
    • Morita T, Sobue K (2009) Specification of neuronal polarity regulated by local translation of CRMP2 and Tau via the mTOR-p70S6K pathway. J Biol Chem 284:27734-27745
    • (2009) J Biol Chem , vol.284 , pp. 27734-27745
    • Morita, T.1    Sobue, K.2
  • 102
    • 0034194152 scopus 로고    scopus 로고
    • Phosphoinositide signaling and the regulation of membrane trafficking in yeast
    • DOI 10.1016/S0968-0004(00)01543-7, PII S0968000400015437
    • Odorizzi G, Babst M, Emr SD (2000) Phosphoinositide signaling and the regulation of membrane trafficking in yeast. Trends Biochem Sci 25:229-235 (Pubitemid 30236220)
    • (2000) Trends in Biochemical Sciences , vol.25 , Issue.5 , pp. 229-235
    • Odorizzi, G.1    Babst, M.2    Emr, S.D.3
  • 104
    • 33846946138 scopus 로고    scopus 로고
    • R-Ras controls axon specification upstream of glycogen synthase kinase-3β through integrin-linked kinase
    • DOI 10.1074/jbc.M607979200
    • Oinuma I, Katoh H, Negishi M (2007) R-Ras controls axon specification upstream of glycogen synthase kinase-3beta through integrin-linked kinase. J Biol Chem 282:303-318 (Pubitemid 47076649)
    • (2007) Journal of Biological Chemistry , vol.282 , Issue.1 , pp. 303-318
    • Oinuma, I.1    Katoh, H.2    Negishi, M.3
  • 109
    • 33746314832 scopus 로고    scopus 로고
    • Searching for ways out of the autism maze: genetic, epigenetic and environmental clues
    • DOI 10.1016/j.tins.2006.05.010, PII S0166223606001111
    • Persico AM, Bourgeron T (2006) Searching for ways out of the autism maze: genetic, epigenetic and environmental clues. Trends Neurosci 29:349-358 (Pubitemid 44108247)
    • (2006) Trends in Neurosciences , vol.29 , Issue.7 , pp. 349-358
    • Persico, A.M.1    Bourgeron, T.2
  • 111
    • 0034611809 scopus 로고    scopus 로고
    • Semaphorin 3A is a chemoattractant for cortical apical dendrites
    • DOI 10.1038/35007001
    • Polleux F, Morrow T, Ghosh A (2000) Semaphorin 3A is a chemoattractant for cortical apical dendrites. Nature 404:567-573 (Pubitemid 30205047)
    • (2000) Nature , vol.404 , Issue.6778 , pp. 567-573
    • Polleux, F.1    Morrow, T.2    Ghosh, A.3
  • 112
    • 0036337484 scopus 로고    scopus 로고
    • Control of cortical interneuron migration by neurotrophins and PI3-kinase signaling
    • Polleux F, Whitford KL, Dijkhuizen PA, Vitalis T, Ghosh A (2002) Control of cortical interneuron migration by neurotrophins and PI3-kinase signaling. Development 129:3147-3160 (Pubitemid 34874289)
    • (2002) Development , vol.129 , Issue.13 , pp. 3147-3160
    • Polleux, F.1    Whitford, K.L.2    Dijkhuizen, P.A.3    Vitalis, T.4    Ghosh, A.5
  • 114
    • 13844312400 scopus 로고    scopus 로고
    • Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex
    • DOI 10.1126/science.1106148
    • Sarbassov DD, Guertin DA, Ali SM, Sabatini DM (2005) Phosphorylation and regulation of Akt/ PKB by the rictor-mTOR complex. Science 307:1098-1101 (Pubitemid 40262113)
    • (2005) Science , vol.307 , Issue.5712 , pp. 1098-1101
    • Sarbassov, D.D.1    Guertin, D.A.2    Ali, S.M.3    Sabatini, D.M.4
  • 115
    • 4344594485 scopus 로고    scopus 로고
    • The sequential activity of the GTPases Rap1B and Cdc42 determines neuronal polarity
    • DOI 10.1038/nn1295
    • Schwamborn JC, Puschel AW (2004) The sequential activity of the GTPases Rap1B and Cdc42 determines neuronal polarity. Nat Neurosci 7:923-929 (Pubitemid 39129500)
    • (2004) Nature Neuroscience , vol.7 , Issue.9 , pp. 923-929
    • Schwamborn, J.C.1    Puschel, A.W.2
  • 116
    • 32144456456 scopus 로고    scopus 로고
    • GTPases and the control of neuronal polarity
    • DOI 10.1016/S0076-6879(06)06056-3, PII S0076687906060563, 56, Regulators and Effectors of Small GTPases: Rho Family
    • Schwamborn JC, Li Y, Puschel AW (2006) GTPases and the control of neuronal polarity. Methods Enzymol 406:715-727 (Pubitemid 43207481)
    • (2006) Methods in Enzymology , vol.406 , pp. 715-727
    • Schwamborn, J.C.1    Li, Y.2    Puschel, A.W.3
  • 117
    • 33646197380 scopus 로고    scopus 로고
    • Combined signaling through ERK, PI3K/AKT, and RAC1/p38 is required for Met-triggered cortical neuron migration
    • DOI 10.1074/jbc.M508298200
    • Segarra J, Balenci L, Drenth T, Maina F, Lamballe F (2006) Combined signaling through ERK, PI3K/AKT, and RAC1/p38 is required for met-triggered cortical neuron migration. J Biol Chem 281:4771-4778 (Pubitemid 43847738)
    • (2006) Journal of Biological Chemistry , vol.281 , Issue.8 , pp. 4771-4778
    • Segarra, J.1    Balenci, L.2    Drenth, T.3    Maina, F.4    Lamballe, F.5
  • 118
    • 0028825345 scopus 로고
    • Abnormally high neuronal density in the schizophrenic cortex A morphometric analysis of prefrontal area 9 and occipital area 17
    • Discussion 819-820
    • Selemon LD, Rajkowska G, Goldman-Rakic PS (1995) Abnormally high neuronal density in the schizophrenic cortex. A morphometric analysis of prefrontal area 9 and occipital area 17. Arch Gen Psychiatry 52:805-818, Discussion 819-820
    • (1995) Arch Gen Psychiatry , vol.52 , pp. 805-818
    • Selemon, L.D.1    Rajkowska, G.2    Goldman-Rakic, P.S.3
  • 119
    • 0037428076 scopus 로고    scopus 로고
    • Hippocampal neuronal polarity specified by spatially localized mPar3/mPar6 and PI 3-kinase activity
    • DOI 10.1016/S0092-8674(02)01249-7
    • Shi SH, Jan LY, Jan YN (2003) Hippocampal neuronal polarity specified by spatially localized mPar3/mPar6 and PI 3-kinase activity. Cell 112:63-75 (Pubitemid 36106419)
    • (2003) Cell , vol.112 , Issue.1 , pp. 63-75
    • Shi, S.-H.1    Jan, L.Y.2    Jan, Y.-N.3
  • 120
    • 0032546462 scopus 로고    scopus 로고
    • Multiple isoforms of the regulatory subunit for phosphatidylinositol 3-kinase (PI3-kinase) are expressed in neurons in the rat brain
    • DOI 10.1006/bbrc.1998.8606
    • Shin BC, Suzuki M, Inukai K, Anai M, Asano T, Takata K (1998) Multiple isoforms of the regulatory subunit for phosphatidylinositol 3-kinase (PI3-kinase) are expressed in neurons in the rat brain. Biochem Biophys Res Commun 246:313-319 (Pubitemid 28412595)
    • (1998) Biochemical and Biophysical Research Communications , vol.246 , Issue.2 , pp. 313-319
    • Shin, B.-C.1    Suzuki, M.2    Inukai, K.3    Anai, M.4    Asano, T.5    Takata, K.6
  • 121
    • 70349919804 scopus 로고    scopus 로고
    • Coordination of membrane events during autophagy by multiple class III PI3-kinase complexes
    • Simonsen A, Tooze SA (2009) Coordination of membrane events during autophagy by multiple class III PI3-kinase complexes. J Cell Biol 186:773-782
    • (2009) J Cell Biol , vol.186 , pp. 773-782
    • Simonsen, A.1    Tooze, S.A.2
  • 128
    • 40449135360 scopus 로고    scopus 로고
    • Learning deficits and agenesis of synapses and myelinated axons in phosphoinositide-3 kinase-deficient mice
    • DOI 10.1159/000108936
    • Tohda C, Nakanishi R, Kadowaki M (2006) Learning deficits and agenesis of synapses and myelinated axons in phosphoinositide-3 kinase-deficient mice. Neurosignals 15:293-306 (Pubitemid 351346928)
    • (2007) NeuroSignals , vol.15 , Issue.6 , pp. 293-306
    • Tohda, C.1    Nakanishi, R.2    Kadowaki, M.3
  • 129
    • 57349164057 scopus 로고    scopus 로고
    • Hyperactivity, memory deficit and anxiety-related behaviors in mice lacking the p85alpha subunit of phosphoinositide-3 kinase
    • Tohda C, Nakanishi R, Kadowaki M (2009) Hyperactivity, memory deficit and anxiety-related behaviors in mice lacking the p85alpha subunit of phosphoinositide-3 kinase. Brain Dev 31:69-74
    • (2009) Brain Dev , vol.31 , pp. 69-74
    • Tohda, C.1    Nakanishi, R.2    Kadowaki, M.3
  • 131
    • 24344433989 scopus 로고    scopus 로고
    • Association between the neuregulin 1 gene and schizophrenia: A systematic review
    • DOI 10.1093/schbul/sbi043
    • Tosato S, Dazzan P, Collier D (2005) Association between the neuregulin 1 gene and schizophrenia: a systematic review. Schizophr Bull 31:613-617 (Pubitemid 41253313)
    • (2005) Schizophrenia Bulletin , vol.31 , Issue.3 , pp. 613-617
    • Tosato, S.1    Dazzan, P.2    Collier, D.3
  • 132
    • 0035086678 scopus 로고    scopus 로고
    • Phosphatidylinositol 3-OH kinase regulatory subunits are differentially expressed during development of the rat cerebellum
    • DOI 10.1002/neu.1014
    • Trejo JL, Pons S (2001) Phosphatidylinositol-3-OH kinase regulatory subunits are differentially expressed during development of the rat cerebellum. J Neurobiol 47:39-50 (Pubitemid 32240152)
    • (2001) Journal of Neurobiology , vol.47 , Issue.1 , pp. 39-50
    • Trejo, J.L.1    Pons, S.2
  • 133
    • 0036886026 scopus 로고    scopus 로고
    • Neurotrophins and the control of axonal outgrowth
    • Tucker KL (2002) Neurotrophins and the control of axonal outgrowth. Panminerva Med 44:325-333 (Pubitemid 41328277)
    • (2002) Panminerva Medica , vol.44 , Issue.4 , pp. 325-333
    • Tucker, K.L.1
  • 134
    • 37149046442 scopus 로고    scopus 로고
    • Function of PTEN during the formation and maintenance of neuronal circuits in the brain
    • DOI 10.1159/000109852
    • van Diepen MT, Eickholt BJ (2008) Function of PTEN during the formation and maintenance of neuronal circuits in the brain. Dev Neurosci 30:59-64 (Pubitemid 350256684)
    • (2008) Developmental Neuroscience , vol.30 , Issue.1-3 , pp. 59-64
    • Van Diepen, M.T.1    Eickholt, B.J.2
  • 138
    • 0038538430 scopus 로고    scopus 로고
    • Phosphoinositide 3-kinase-dependent activation of Rac
    • DOI 10.1016/S0014-5793(03)00454-X
    • Welch HC, Coadwell WJ, Stephens LR, Hawkins PT (2003) Phosphoinositide 3-kinase-dependent activation of Rac. FEBS Lett 546:93-97 (Pubitemid 36782287)
    • (2003) FEBS Letters , vol.546 , Issue.1 , pp. 93-97
    • Welch, H.C.E.1    Coadwell, W.J.2    Stephens, L.R.3    Hawkins, P.T.4
  • 139
    • 19944381540 scopus 로고    scopus 로고
    • Polarity proteins in axon specification and synaptogenesis
    • DOI 10.1016/j.devcel.2005.05.007, PII S1534580705001760
    • Wiggin GR, Fawcett JP, Pawson T (2005) Polarity proteins in axon specification and synaptogenesis. Dev Cell 8:803-816 (Pubitemid 40754053)
    • (2005) Developmental Cell , vol.8 , Issue.6 , pp. 803-816
    • Wiggin, G.R.1    Fawcett, J.P.2    Pawson, T.3
  • 140
    • 6344271762 scopus 로고    scopus 로고
    • Autism and tuberous sclerosis
    • Wiznitzer M (2004) Autism and tuberous sclerosis. J Child Neurol 19:675-679 (Pubitemid 39530076)
    • (2004) Journal of Child Neurology , vol.19 , Issue.9 , pp. 675-679
    • Wiznitzer, M.1
  • 141
    • 33746657223 scopus 로고    scopus 로고
    • Requirement of dendritic Akt degradation by the ubiquitin-proteasome system for neuronal polarity
    • DOI 10.1083/jcb.200511028
    • Yan D, Guo L, Wang Y (2006) Requirement of dendritic Akt degradation by the ubiquitinproteasome system for neuronal polarity. J Cell Biol 174:415-424 (Pubitemid 44156771)
    • (2006) Journal of Cell Biology , vol.174 , Issue.3 , pp. 415-424
    • Yan, D.1    Guo, L.2    Wang, Y.3
  • 142
    • 0035155025 scopus 로고    scopus 로고
    • PI-3 kinase and IP3 are both necessary and sufficient to mediate NT3-induced synaptic potentiation
    • DOI 10.1038/82858
    • Yang F, He X, Feng L, Mizuno K, Liu XW, Russell J, Xiong WC, Lu B (2001) PI-3 kinase and IP3 are both necessary and sufficient to mediate NT3-induced synaptic potentiation. Nat Neurosci 4:19-28 (Pubitemid 32095522)
    • (2001) Nature Neuroscience , vol.4 , Issue.1 , pp. 19-28
    • Yang, F.1    He, X.-P.2    Feng, L.3    Mizuno, K.4    Liu, X.-W.5    Russell, J.6    Xiong, W.-C.7    Lu, B.8
  • 145
    • 2942735115 scopus 로고    scopus 로고
    • NGF-induced axon growth is mediated by localized inactivation of GSK-3β and functions of the microtubule plus end binding protein APC
    • DOI 10.1016/j.neuron.2004.05.011, PII S0896627304002958
    • Zhou FQ, Zhou J, Dedhar S, Wu YH, Snider WD (2004) NGF-induced axon growth is mediated by localized inactivation of GSK-3beta and functions of the microtubule plus end binding protein APC. Neuron 42:897-912 (Pubitemid 38798229)
    • (2004) Neuron , vol.42 , Issue.6 , pp. 897-912
    • Zhou, F.-Q.1    Zhou, J.2    Dedhar, S.3    Wu, Y.-H.4    Snider, W.D.5
  • 146
    • 60849109211 scopus 로고    scopus 로고
    • Pharmacological inhibition of mTORC1 suppresses anatomical, cellular, and behavioral abnormalities in neural-specific Pten knock-out mice
    • Zhou J, Blundell J, Ogawa S, Kwon CH, Zhang W, Sinton C, Powell CM, Parada LF (2009) Pharmacological inhibition of mTORC1 suppresses anatomical, cellular, and behavioral abnormalities in neural-specific Pten knock-out mice. J Neurosci 29:1773-1783
    • (2009) J Neurosci , vol.29 , pp. 1773-1783
    • Zhou, J.1    Blundell, J.2    Ogawa, S.3    Kwon, C.H.4    Zhang, W.5    Sinton, C.6    Powell, C.M.7    Parada, L.F.8
  • 147
    • 0037162696 scopus 로고    scopus 로고
    • Ras and Rap control AMPA receptor trafficking during synaptic plasticity
    • DOI 10.1016/S0092-8674(02)00897-8
    • Zhu JJ, Qin Y, Zhao M, Van Aelst L, Malinow R (2002) Ras and Rap control AMPA receptor trafficking during synaptic plasticity. Cell 110:443-455 (Pubitemid 35232288)
    • (2002) Cell , vol.110 , Issue.4 , pp. 443-455
    • Zhu J.Julius1    Qin, Y.2    Zhao, M.3    Van Aelst, L.4    Malinow, R.5
  • 148
    • 0031741226 scopus 로고    scopus 로고
    • Germline PTEN mutation in a family with Cowden syndrome and Bannayan-Riley-Ruvalcaba syndrome
    • Zori RT,Marsh DJ, Graham GE, Marliss EB, Eng C (1998) Germline PTEN mutation in a family with Cowden syndrome and Bannayan-Riley-Ruvalcaba syndrome. Am J Med Genet 80:399-402
    • (1998) Am J Med Genet , vol.80 , pp. 399-402
    • Zori, R.T.1    Marsh, D.J.2    Graham, G.E.3    Marliss, E.B.4    Eng, C.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.