Arachidonic acid released by phospholipase A2 activation triggers Ca2+-dependent apoptosis through the mitochondrial pathway

Journal of Biological Chemistry

Volumn 279, Issue 24, 2004, Pages 25219-25225

  Penzo, Daniele ^a,c   Petronilli, Valeria ^a   Angelin, Alessia ^a   Cusan, Claudia ^b   Colonna, Raffaele ^a   Scorrano, Luca ^c   Pagano, Francesco ^c   Prato, Maurizio ^a   Di Lisa, Fabio ^a   Bernardi, Paolo ^a,c  

^a UNIVERSITY OF PADOVA   (Italy)

^b UNIVERSITY OF TRIESTE   (Italy)

^c VENETIAN INSTITUTE OF MOLECULAR MEDICINE   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOLOGY; ENZYMES; HYDROLYSIS; PHOSPHOLIPIDS;

APOPTOSIS; CELL DEATH; MITOCHONDRIAL PATHWAYS; PERMEABILITY TRANSITION PORES (PTP);

BIOCHEMISTRY;

3 [3 TERT BUTYLTHIO 1 (4 CHLOROBENZYL) 5 ISOPROPYL 2 INDOLYL] 2,2 DIMETHYLPROPIONIC ACID; ARACHIDONATE 5 LIPOXYGENASE; ARACHIDONIC ACID; ARISTOLOCHIC ACID; CALCIMYCIN; CALCIUM ION; CASPASE 3; CASPASE 8; CASPASE 9; CYCLOSPORIN A; CYTOCHROME C; INDOMETACIN; LEUKOTRIENE; PHOSPHOLIPASE A2; PHOSPHOLIPID; PROSTAGLANDIN; PROSTAGLANDIN SYNTHASE; THAPSIGARGIN;

ANIMAL CELL; APOPTOSIS; ARACHIDONIC ACID METABOLISM; ARTICLE; CALCIUM CELL LEVEL; CALCIUM HOMEOSTASIS; CELL DEATH; CELL KILLING; CELL POPULATION; CHANNEL GATING; ENZYME ACTIVATION; ENZYME DEGRADATION; MEMBRANE PERMEABILITY; MITOCHONDRIAL MEMBRANE; MITOCHONDRION; NONHUMAN; PERMEABILITY TRANSITION PORE; PRIORITY JOURNAL; RAT; SIGNAL TRANSDUCTION;

ANIMALS; APOPTOSIS; ARACHIDONIC ACID; ARISTOLOCHIC ACIDS; CALCIMYCIN; CALCIUM; CELLS, CULTURED; ENZYME ACTIVATION; INDOLES; INDOMETHACIN; MITOCHONDRIA; PHOSPHOLIPASES A; PHOSPHOLIPIDS; RATS;

ANIMALIA;

EID: 2942530420     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M310381200     Document Type: Article

References (52)

1. Shen, A. C., and Jennings, R. B. (1972) Am. J. Pathol. 67, 417-440
2. Fleckenstein, A., Janke, J., Doring, H. J., and Leder, O. (1974) Rec. Adv. Stud. Cardiac. Struct. Metab. 4, 563-580
3. Orrenius, S., Zhivotovsky, B., and Nicotera, P. (2003) Nat. Rev. Mol. Cell. Biol. 4, 552-565
4. Rizzuto, R., Bernardi, P., and Pozzan, T. (2000) J. Physiol. (Lond.) 529, 37-47
5. Bernardi, P. (1999) Physiol. Rev. 79, 1127-1155
6. Bernardi, P., Petronilli, V., Di Lisa, F., and Forte, M. (2001) Trends Biochem. Sci. 26, 112-117
7. Scorrano, L., Ashiya, M., Buttle, K., Weiler, S., Oakes, S. A., Mannella, C. A., and Korsmeyer, S. J. (2002) Dev. Cell 2, 55-67
8. Petronilli, V., Miotto, G., Canton, M., Colonna, R., Bernardi, P., and Di Lisa, F. (1999) Biophys. J. 76, 725-734
9. Petronilli, V., Penzo, D., Scorrano, L., Bernardi, P., and Di Lisa F. (2001) J. Biol. Chem. 276, 12030-12034
10. Nicolli, A., Petronilli, V., and Bernardi, P. (1993) Biochemistry 32, 4461-4465
11. Arora, A. S., Jones, B. J., Patel, T. C., Bronk, S. F., and Gores, G. J. (1997) Hepatology 25, 958-963
12. Pacher, P., and Hajnoczky, G. (2001) EMBO J. 20, 4107-4121
13. Scorrano, L., Petronilli, V., Di Lisa, F., and Bernardi, P. (1999) J. Biol. Chem. 274, 22581-22585
14. Rippo, M. R., Malisan, F., Ravagnan, L., Tomassini, B., Condo, I., Costantini, P., Susin, S. A., Rufini, A., Todaro, M., Kroemer, G., and Testi, R. (2000) FASEB J. 14, 2047-2054
15. Garcia-Ruiz, C., Colell, A., Paris, R., and Fernandez-Checa, J. C. (2000) FASEB J. 14, 847-858
16. Kristal, B. S., and Brown, A. M. (1999) J. Biol. Chem. 274, 23169-23175
17. Scorrano, L., Penzo, D., Petronilli, V., Pagano, F., and Bernardi, P. (2001) J. Biol. Chem. 276, 12035-12040
18. Gugliucci, A., Ranzato, L., Scorrano, L., Colonna, R., Petronilli, V., Cusan, C., Prato, M., Mancini, M., Pagano, F., and Bernardi, P. (2002) J. Biol. Chem. 277, 31789-31795
19. Penzo, D., Tagliapietra, C., Colonna, R., Petronilli, V., and Bernardi, P. (2002) Biochim. Biophys. Acta Bioenerg. 1555, 160-165
20. Hayakawa, M., Ishida, N., Takeuchi, K., Shibamoto, S., Hori, T., Oku, N., Ito, F., and Tsujimoto, M. (1993) J. Biol. Chem. 268, 11290-11295
21. Pastorino, J. G., Simbula, G., Yamamoto, K., Glascott, P. A. Jr., Rothman, R. J., and Farber, J. L. (1996) J. Biol. Chem. 271, 29792-29798
22. Chan, T. A., Morin, P. J., Vogelstein, B., and Kinzler, K. W., (1998) Proc. Natl. Acad. Sci. U. S. A. 95, 681-686
23. Cao, Y., Pearman, A. T., Zimmerman, G. A., McIntyre, T. M., and Prescott, S. M. (2000) Proc. Natl. Acad. Sci. U. S. A. 97, 11280-11285
24. Simbula, G., Glascott, P. A., Jr., Akita, S., Hoek, J. B., and Farber, J. L. (1997) Am. J. Physiol. 273, C479-C488
25. Michel, P. P., Vyas, S., Anglade, P., Ruberg, M., and Agid, Y. (1994) Eur. J. Neurosci. 6, 577-586
26. Mattson, M. P., Rychlik, B., Chu, C., and Christakos, S. (1991) Neuron 6, 41-51
27. Lukas, W., and Jones, K. A. (1994) Neuroscience 61, 307-316
28. Qian, T., Herman, B., and Lemasters, J. J. (1999) Toxicol. Appl. Pharmacol. 154, 117-125
29. Petersen, A., Castilho, R. F., Hansson, O., Wieloch, T., and Brundin, P. (2000) Brain Res. 857, 20-29
30. Gwag, B. J., Canzoniero, L. M., Sensi, S. L., Demaro, J. A., Koh, J. Y., Goldberg, M. P., Jacquin, M., and Choi, D. W. (1999) Neuroscience 90, 1339-1348
31. Takadera, T., and Ohyashiki, T. (1997) Eur. J. Biochem. 249, 8-12
32. Bernardi, P., Scorrano, L., Colonna, R., Petronilli, V., and Di Lisa F. (1999) Eur. J. Biochem. 264, 687-701
33. Bligh, E. G., and Dyer, W. J. (1959) Can. J. Biochem. Physiol. 37, 911-917
34. Gijon, M. A., and Leslie, C. C. (1999) J. Leukoc. Biol. 65, 330-336
35. Hirabayashi, T., and Shimizu, T. (2000) Biochim. Biophys. Acta 1488, 124-138
36. Grewal, S., Ponnambalam, S., and Walker, J. H. (2003) J. Cell Sci. 116, 2303-2310
37. Pouliot, M., McDonald, P. P., Krump, E., Mancini, J. A., McColl, S. R., Weech, P. K., and Borgeat, P. (1996) Eur. J. Biochem. 238, 250-258
38. Chandra, V., Jasti, J., Kaur, P., Srinivasan, A., Betzel, C., and Singh, T. P. (2002) Biochemistry 41, 10914-10919
39. Vishwanath, B. S., Fawzy, A. A., and Franson, R. C. (1988) Inflammation 12, 549-561
40. Rosenthal, M. D., Vishwanath, B. S., and Franson, R. C. (1989) Biochim. Biophys. Acta 1001, 1-8
41. Reed, P. W., and Lardy, H. A. (1972) J. Biol. Chem. 247, 6970-6977
42. Pfeiffer, D. R., and Lardy, H. A. (1976) Biochemistry 15, 935-943
43. Dordick, R. S., Brierley, G. P., and Garlid, K. D. (1980) J. Biol. Chem. 255, 10299-10305
44. Babcock, D. F., First, N. L., and Lardy, H. A. (1976) J. Biol. Chem. 251, 3881-3886
45. Pickett, W. C., Jesse, R. L., and Cohen, P. (1976) Biochim. Biophys. Acta 486, 209-213
46. Borgeat, P., and Samuelsson, B. (1979) Proc. Natl. Acad. Sci. U. S. A. 76, 2148-2152
47. Jayadev, S., Linardic, C. M., and Hannun, Y. A. (1994) J. Biol. Chem. 269, 5757-5763
48. Jayadev, S., Hayter, H. L., Andrieu, N., Gamard, C. J., Liu, B., Balu, R., Hayakawa, M., Ito, F., and Hannun, Y. A. (1997) J. Biol. Chem. 272, 17196-17203
49. Garcia-Ruiz, C., Colell, A., Mari, M., Morales, A., and Fernandez-Checa, J. C. (1997) J. Biol. Chem. 272, 11369-11377
50. Garcia-Ruiz, C., Colell, A., Morales, A., Calvo, M., Enrich, C., and Fernandez-Checa, J. C. (2002) J. Biol. Chem. 277, 36443-36448
51. Garcia-Ruiz, C., Colell, A., Mari, M., Morales, A., Calvo, M., Enrich, C., and Fernandez-Checa, J. C. (2003) J. Clin. Investig. 111, 197-208
52. De Maria, R., Lenti, L., Malisan, F., d'Agostino, F., Tomassini, B., Zeuner, A., Rippo, M. R., and Testi, R. (1997) Science 277, 1652-1655