-
1
-
-
0032707190
-
Type 2 diabetes mellitus, cognitive impairment and dementia
-
Stewart R, Liolitsa D. Type 2 diabetes mellitus, cognitive impairment and dementia. Diabetic Medicine 1999; 16:93-112.
-
(1999)
Diabetic Medicine
, vol.16
, pp. 93-112
-
-
Stewart, R.1
Liolitsa, D.2
-
2
-
-
36448936053
-
Common pathological processes in Alzheimer disease and type 2 diabetes: A review
-
Li L, Holscher C. Common pathological processes in Alzheimer disease and type 2 diabetes: a review. Brain Res Rev 2007; 56:384-402.
-
(2007)
Brain Res Rev
, vol.56
, pp. 384-402
-
-
Li, L.1
Holscher, C.2
-
3
-
-
0032764016
-
Diabetes mellitus and the risk of dementia: The Rotterdam Study
-
Ott A, Stolk RP, van Harskamp F et al. Diabetes mellitus and the risk of dementia: The Rotterdam Study.Neurology 1999; 58:1937-1941.
-
(1999)
Neurology
, vol.58
, pp. 1937-1941
-
-
Ott, A.1
Stolk, R.P.2
Van Harskamp, F.3
-
4
-
-
2442424380
-
Diabetes mellitus and risk of Alzheimer's disease and decline in cognitive function
-
Arvanitakis Z, Wilson RS, Bienias JL et al. Diabetes mellitus and risk of Alzheimer's disease and decline in cognitive function. Arch Neurol 2004; 61:661-666.
-
(2004)
Arch Neurol
, vol.61
, pp. 661-666
-
-
Arvanitakis, Z.1
Wilson, R.S.2
Bienias, J.L.3
-
5
-
-
0036227542
-
Honolulu-Asia Aging Study. Type 2 diabetes, APOE gene and the risk fordementiaandrelatedpathologies
-
Peila R, Rodriguez BL, Launer LJ. Honolulu-Asia Aging Study. Type 2 diabetes, APOE gene and the risk fordementiaandrelatedpathologies. Diabetes 2002; 51:1256-1262.
-
(2002)
Diabetes
, vol.51
, pp. 1256-1262
-
-
Peila, R.1
Rodriguez, B.L.2
Launer, L.J.3
-
6
-
-
3242765976
-
Fasting insulin and incident dementia in an elderly population of Japanese-American men
-
Peila R, Rodriguez BL, White LR et al. Fasting insulin and incident dementia in an elderly population of Japanese-American men. Neurology 2004; 63:228-233.
-
(2004)
Neurology
, vol.63
, pp. 228-233
-
-
Peila, R.1
Rodriguez, B.L.2
White, L.R.3
-
7
-
-
0036144081
-
Prevalence and risk factors of silent brain infarcts in the population-based Rotterdam Scan Study
-
Vermeer SE, Koudstaal PJ, Oudkerk M et al. Prevalence and risk factors of silent brain infarcts in the population-based Rotterdam Scan Study. Stroke 2002; 33:21-25.
-
(2002)
Stroke
, vol.33
, pp. 21-25
-
-
Vermeer, S.E.1
Koudstaal, P.J.2
Oudkerk, M.3
-
8
-
-
0035132684
-
Prevalence of cerebral white matter lesions in elderly people: A population based magnetic resonance imaging study. the Rotterdam Scan Study
-
de Leeuw FE, de Groot JC, Achten E et al. Prevalence of cerebral white matter lesions in elderly people: a population based magnetic resonance imaging study. The Rotterdam Scan Study. J Neurol Neurosurg Psychiatry 2001; 70:9-14.
-
(2001)
J Neurol Neurosurg Psychiatry
, vol.70
, pp. 9-14
-
-
De Leeuw, F.E.1
De Groot, J.C.2
Achten, E.3
-
9
-
-
0346216156
-
Type 2 diabetes and atrophy of medial temporal lobe structures on brain MRI
-
den Heijer T, Vermeer SE, van Dijk EJ et al. Type 2 diabetes and atrophy of medial temporal lobe structures on brain MRI. Diabetologia 2003; 46:1604-1610.
-
(2003)
Diabetologia
, vol.46
, pp. 1604-1610
-
-
Den Heijer, T.1
Vermeer, S.E.2
Van Dijk, E.J.3
-
10
-
-
33845462866
-
Brain aging in very old men with type 2 diabetes: The Honolulu-Asia Aging Study
-
Korf ES, White LR, Scheltens P et al. Brain aging in very old men with type 2 diabetes: the Honolulu-Asia Aging Study. Diabetes Care 2006; 29:2268-2274.
-
(2006)
Diabetes Care
, vol.29
, pp. 2268-2274
-
-
Korf, E.S.1
White, L.R.2
Scheltens, P.3
-
11
-
-
33846648054
-
Diabetes mellitus, hypertension and medial temporal lobe atrophy: The LADIS study
-
LADIS Study Group
-
Korf ES, van Straaten EC, de Leeuw FE et al. LADIS Study Group. Diabetes mellitus, hypertension and medial temporal lobe atrophy: the LADIS study. Diabet Med 2007; 24:166-171.
-
(2007)
Diabet Med
, vol.24
, pp. 166-171
-
-
Korf, E.S.1
Van Straaten, E.C.2
De Leeuw, F.E.3
-
12
-
-
35748972367
-
Food-derived advanced glycation end products (AGEs): A novel therapeutic target for various disorders
-
Yamagishi S, UedaS, OkudaS. Food-derived advanced glycation end products (AGEs): a novel therapeutic target for various disorders. Curr Pharm Des 2007; 13:2832-2836.
-
(2007)
Curr Pharm des
, vol.13
, pp. 2832-2836
-
-
Yamagishi, S.1
Ueda, S.2
Okuda, S.3
-
13
-
-
70449732132
-
Immunohistochemical analysis of human brain suggests pathological synergism of Alzheimer's disease and diabetes mellitus
-
Valente T, Gella A, Fernandez-Busquets X et al. Immunohistochemical analysis of human brain suggests pathological synergism of Alzheimer's disease and diabetes mellitus. Neurobiol Dis 2010; 37:67-76.
-
(2010)
Neurobiol Dis
, vol.37
, pp. 67-76
-
-
Valente, T.1
Gella, A.2
Fernandez-Busquets, X.3
-
14
-
-
33845768784
-
Microglia-mediated neurotoxicity: Uncovering the molecular mechanisms
-
Block ML, Zecca L, Hong JS. Microglia-mediated neurotoxicity: uncovering the molecular mechanisms. Nat Rev Neurosci 2007; 8:57-69.
-
(2007)
Nat Rev Neurosci
, vol.8
, pp. 57-69
-
-
Block, M.L.1
Zecca, L.2
Hong, J.S.3
-
15
-
-
0036796875
-
Oxidative stress and stress-activated signaling pathways: A unifying hypothesis of type 2 diabetes
-
Evans JL, Goldfrne ID, Maddux BA et al. Oxidative stress and stress-activated signaling pathways: a unifying hypothesis of type 2 diabetes. Endocr Rev 2002; 23:599-622.
-
(2002)
Endocr Rev
, vol.23
, pp. 599-622
-
-
Evans, J.L.1
Goldfrne, I.D.2
Maddux, B.A.3
-
16
-
-
34249821079
-
Brain mitochondrial dysfunction as a link between Alzheimer's disease and diabetes
-
Moreira PI, Santos MS, Seica R et al. Brain mitochondrial dysfunction as a link between Alzheimer's disease and diabetes. J Neurol Sci 2007; 257:206-214.
-
(2007)
J Neurol Sci
, vol.257
, pp. 206-214
-
-
Moreira, P.I.1
Santos, M.S.2
Seica, R.3
-
17
-
-
0037221379
-
The role of insulin resistance in the pathogenesis of Alzheimer's disease: Implications fortreatment
-
Watson GS, Craft S. The role of insulin resistance in the pathogenesis of Alzheimer's disease: implications fortreatment. CNS Drugs 2003; 17:27-45.
-
(2003)
CNS Drugs
, vol.17
, pp. 27-45
-
-
Watson, G.S.1
Craft, S.2
-
18
-
-
0002096610
-
Insulin, oral hypoglycemic agents and the pharmacology of the endocrine pancreas
-
Hardman JG, Gilman AG, Limbird LE, eds. 9th. New York: McGraw-Hill
-
Davis SN, Granner DK. Insulin, oral hypoglycemic agents and the pharmacology of the endocrine pancreas. In: Hardman JG, Gilman AG, Limbird LE, eds. Gilman and Goodman's the Pharmacological Basis of Ttherapeutics, 9th. New York: McGraw-Hill, 1996:1487-1517.
-
(1996)
Gilman and Goodman's the Pharmacological Basis of Ttherapeutics
, pp. 1487-1517
-
-
Davis, S.N.1
Granner, D.K.2
-
20
-
-
0018090354
-
Insulin receptors are widely distributed in the central nervous system oftherat
-
Havrankova J, Roth J, Brownstein M. Insulin receptors are widely distributed in the central nervous system oftherat. Nature 1978; 272:827-829.
-
(1978)
Nature
, vol.272
, pp. 827-829
-
-
Havrankova, J.1
Roth, J.2
Brownstein, M.3
-
21
-
-
0034508636
-
Insulin receptors and insulin action in the nervous system
-
Freychet P. Insulin receptors and insulin action in the nervous system. Diab Metab Res Rev 2000; 16:390-392.
-
(2000)
Diab Metab Res Rev
, vol.16
, pp. 390-392
-
-
Freychet, P.1
-
22
-
-
33644591150
-
Insulin and insulin-like growth factor expression and function deteriorate with progression of Alzheimer's disease: Link to brain reductions in acetylcholine
-
Rivera EJ, Goldin A, Fulmer N et al. Insulin and insulin-like growth factor expression and function deteriorate with progression of Alzheimer's disease: link to brain reductions in acetylcholine. J Alzheimers Dis 2005; 8:247-268.
-
(2005)
J Alzheimers Dis
, vol.8
, pp. 247-268
-
-
Rivera, E.J.1
Goldin, A.2
Fulmer, N.3
-
23
-
-
20844458090
-
Synaptic targeting by Alzheimer's-related amyloid beta oligomers
-
Lacor PN, Buniel MC,Chang L et al. Synaptic targeting by Alzheimer's-related amyloid beta oligomers. J Neurosci 2004; 24:10191-10200.
-
(2004)
J Neurosci
, vol.24
, pp. 10191-10200
-
-
Lacor, P.N.1
Buniel, M.C.2
Chang, L.3
-
24
-
-
0037041426
-
Naturally secreted oligomers of amyloid beta protein potently inhibit hippocampal long-term potentiation in vivo
-
Walsh DM, Klyubin I, Fadeeva JV et al. Naturally secreted oligomers of amyloid beta protein potently inhibit hippocampal long-term potentiation in vivo. Nature 2002; 416:535-539.
-
(2002)
Nature
, vol.416
, pp. 535-539
-
-
Walsh, D.M.1
Klyubin, I.2
Fadeeva, J.V.3
-
25
-
-
77954545211
-
Efficacy of PPAR-gamma agonist pioglitazone in mild Alzheimer disease
-
[Epub ahead of print]
-
Sato T, Hanyu H, Hirao K et al. Efficacy of PPAR-gamma agonist pioglitazone in mild Alzheimer disease. Neurobiol Aging 2009. [Epub ahead of print]
-
(2009)
Neurobiol Aging
-
-
Sato, T.1
Hanyu, H.2
Hirao, K.3
-
26
-
-
64249129005
-
Insulin resistance and amyloidogenesis as common molecular foundation for type 2 diabetes and Alzheimer's disease
-
Zhao WQ, Townsend M. Insulin resistance and amyloidogenesis as common molecular foundation for type 2 diabetes and Alzheimer's disease. Biochim Biophys Acta 2009; 1792:482-496.
-
(2009)
Biochim Biophys Acta
, vol.1792
, pp. 482-496
-
-
Zhao, W.Q.1
Townsend, M.2
-
27
-
-
0031907459
-
Cerebrospinal fluid and plasma insulin levels in Alzheimer's disease: Relationship to severity of dementia and apolipoprotein e genotype
-
Craft S, Peskind E, Schwartz MW et al. Cerebrospinal fluid and plasma insulin levels in Alzheimer's disease: relationship to severity of dementia and apolipoprotein E genotype. Neurology 1998;50:164-168.
-
(1998)
Neurology
, vol.50
, pp. 164-168
-
-
Craft, S.1
Peskind, E.2
Schwartz, M.W.3
-
28
-
-
40349091597
-
Intranasal insulin improves cognition and modulates beta-amyloid in early AD
-
Reger MA, Watson GS, Green PS et al. Intranasal insulin improves cognition and modulates beta-amyloid in early AD. Neurology 2008; 70:440-448.
-
(2008)
Neurology
, vol.70
, pp. 440-448
-
-
Reger, M.A.1
Watson, G.S.2
Green, P.S.3
-
29
-
-
3242740239
-
Delivery of insulin-like growth factor-I to the rat brain and spinal cord along olfactory and trigeminal pathways following intranasal administration
-
Thorne RG, Pronk GJ, Padmanabhan V et al. Delivery of insulin-like growth factor-I to the rat brain and spinal cord along olfactory and trigeminal pathways following intranasal administration. Neuroscience 2004; 127:481-496.
-
(2004)
Neuroscience
, vol.127
, pp. 481-496
-
-
Thorne, R.G.1
Pronk, G.J.2
Padmanabhan, V.3
-
30
-
-
3543142498
-
Intranasal insulin reportedly improves memory and attention in humans
-
Benedict C, Hallschmid M, Hatke A et al. Intranasal insulin reportedly improves memory and attention in humans. Psychoneuroendocrinology 2004; 29:1326-1334.
-
(2004)
Psychoneuroendocrinology
, vol.29
, pp. 1326-1334
-
-
Benedict, C.1
Hallschmid, M.2
Hatke, A.3
-
31
-
-
21044455285
-
Type 2 diabetes is negatively associated with Alzheimer's disease neuropathology
-
Beeri MS, Silverman JM, Davis KL et al. Type 2 diabetes is negatively associated with Alzheimer's disease neuropathology. J Gerontol A Biol Sci Med Sci 2005; 60:471-475.
-
(2005)
J Gerontol A Biol Sci Med Sci
, vol.60
, pp. 471-475
-
-
Beeri, M.S.1
Silverman, J.M.2
Davis, K.L.3
-
32
-
-
33845704496
-
Diabetes is related to cerebral infarction but not to AD pathology in older persons
-
Arvanitakis Z, Schneider JA, Wilson RS et al. Diabetes is related to cerebral infarction but not to AD pathology in older persons. Neurology 2006; 7:960-1965.
-
(2006)
Neurology
, vol.7
, pp. 960-1965
-
-
Arvanitakis, Z.1
Schneider, J.A.2
Wilson, R.S.3
-
33
-
-
1242331823
-
Is Alzheimer's disease a neurodegenerative or a vascular disorder? Data, dogma and dialectics
-
de la Torre JC. Is Alzheimer's disease a neurodegenerative or a vascular disorder? Data, dogma and dialectics. Lancet Neurol 2004; 3:184-190.
-
(2004)
Lancet Neurol
, vol.3
, pp. 184-190
-
-
De La Torre, J.C.1
-
34
-
-
4444313311
-
Effect of vascular lesions on cognition in Alzheimer's disease: A community-based study
-
Riekse RG, Leverenz JB, McCormick W et al. Effect of vascular lesions on cognition in Alzheimer's disease: a community-based study. J Am Geriatr Soc 2004; 52:1442-1448.
-
(2004)
J Am Geriatr Soc
, vol.52
, pp. 1442-1448
-
-
Riekse, R.G.1
Leverenz, J.B.2
McCormick, W.3
-
35
-
-
33749001980
-
Cognitive dysfunction associates with white matter hyperintensities and subcortical atrophy on magnetic resonance imaging of the elderly diabetes mellitus. Japanese elderly diabetes intervention trial (J-EDIT)
-
Akisaki T, Sakurai T, Takata T et al. Cognitive dysfunction associates with white matter hyperintensities and subcortical atrophy on magnetic resonance imaging of the elderly diabetes mellitus. Japanese elderly diabetes intervention trial (J-EDIT). Diabetes Metab Res Rev 2006; 22:376-384.
-
(2006)
Diabetes Metab Res Rev
, vol.22
, pp. 376-384
-
-
Akisaki, T.1
Sakurai, T.2
Takata, T.3
-
36
-
-
47049129183
-
Glucose control levels, ischaemic brain lesions and hyperinsulinaemia were associated with cognitive dysfunction in diabetic elderly
-
Umegaki H, Kawamura T, Mogi N et al. Glucose control levels, ischaemic brain lesions and hyperinsulinaemia were associated with cognitive dysfunction in diabetic elderly. Age Ageing 2008; 37:458-461.
-
(2008)
Age Ageing
, vol.37
, pp. 458-461
-
-
Umegaki, H.1
Kawamura, T.2
Mogi, N.3
-
37
-
-
33644658866
-
Factors associated with cognitive impairment in elderly patients with diabetes mellitus
-
Suzuki M, Umegaki H, Ieda S et al. Factors associated with cognitive impairment in elderly patients with diabetes mellitus. J Am Geriatr Soc 2006; 54:558-559.
-
(2006)
J Am Geriatr Soc
, vol.54
, pp. 558-559
-
-
Suzuki, M.1
Umegaki, H.2
Ieda, S.3
-
38
-
-
62449286253
-
Different patterns of cerebral injury in dementia with or without diabetes
-
Sonnen JA, Larson EB, Brickell K et al. Different patterns of cerebral injury in dementia with or without diabetes. Arch Neurol 2009; 66:315-322.
-
(2009)
Arch Neurol
, vol.66
, pp. 315-322
-
-
Sonnen, J.A.1
Larson, E.B.2
Brickell, K.3
-
39
-
-
2442424380
-
Diabetes mellitus and risk of Alzheimer disease and decline in cognitive function
-
Arvanitakis Z, Wilson RS, Bienias JL et al. Diabetes mellitus and risk of Alzheimer disease and decline in cognitive function. Arch Neurol 2004; 61:661-666.
-
(2004)
Arch Neurol
, vol.61
, pp. 661-666
-
-
Arvanitakis, Z.1
Wilson, R.S.2
Bienias, J.L.3
-
40
-
-
0037426416
-
Relation of cerebral infarctions to dementia and cognitive function in older persons
-
Schneider JA, Wilson RS, Cochran EJ et al. Relation of cerebral infarctions to dementia and cognitive function in older persons. Neurology 2003; 60:1082-1088.
-
(2003)
Neurology
, vol.60
, pp. 1082-1088
-
-
Schneider, J.A.1
Wilson, R.S.2
Cochran, E.J.3
-
41
-
-
46949106968
-
Incident dementia and blood pressure lowering in the hypertension in the very elderly trial cognitive function assessment (HYVET-COG): A double-blind, placebo controlled trial
-
Peters R, Beckett N, Forette F et al. Incident dementia and blood pressure lowering in the hypertension in the very elderly trial cognitive function assessment (HYVET-COG): a double-blind, placebo controlled trial. Lancet Neurol 2008; 7:683-689.
-
(2008)
Lancet Neurol
, vol.7
, pp. 683-689
-
-
Peters, R.1
Beckett, N.2
Forette, F.3
-
42
-
-
61849132879
-
Relationship between baseline glycemic control and cognitive function in individuals with type 2 diabetes and other cardiovascular risk factors: The action to control cardiovascular risk in diabetes-memory in diabetes (ACCORD-MIND) trial; Action to Control Cardiovascular Risk in Diabetes-Memory in Diabetes (ACCORD-MIND) Investigators
-
Cukierman-Yaffe T, Gerstein HC, Williamson JD et al. Relationship between baseline glycemic control and cognitive function in individuals with type 2 diabetes and other cardiovascular risk factors: the action to control cardiovascular risk in diabetes-memory in diabetes (ACCORD-MIND) trial; Action to Control Cardiovascular Risk in Diabetes-Memory in Diabetes (ACCORD-MIND) Investigators. Diabetes Care 2009; 32:221-226.
-
(2009)
Diabetes Care
, vol.32
, pp. 221-226
-
-
Cukierman-Yaffe, T.1
Gerstein, H.C.2
Williamson, J.D.3
-
43
-
-
57649101378
-
Diabetes as a risk factor for cognitive decline in older patients
-
LSA Study Group
-
Maggi S, Limongi F, Noale M et al. LSA Study Group. Diabetes as a risk factor for cognitive decline in older patients. Dement Geriatr Cogn Disord 2009; 27:24-33.
-
(2009)
Dement Geriatr Cogn Disord
, vol.27
, pp. 24-33
-
-
Maggi, S.1
Limongi, F.2
Noale, M.3
-
44
-
-
43849083580
-
Post-mortem correlates of in vivo PiB-PET amyloid imaging in a typical case of Alzheimer's disease
-
Ikonomovic MD, Klunk WE, Abrahamson EE et al. Post-mortem correlates of in vivo PiB-PET amyloid imaging in a typical case of Alzheimer's disease. Brain 2008; 131:1630-1645.
-
(2008)
Brain
, vol.131
, pp. 1630-1645
-
-
Ikonomovic, M.D.1
Klunk, W.E.2
Abrahamson, E.E.3
-
45
-
-
64749114159
-
Hypoglycemic episodes and risk of dementia in older patients with type 2 diabetes mellitus
-
Whitmer RA, Karter AJ, Yaffe K et al. Hypoglycemic episodes and risk of dementia in older patients with type 2 diabetes mellitus. JAMA 15; 301:1565-1572.
-
JAMA
, vol.15
, Issue.301
, pp. 1565-1572
-
-
Whitmer, R.A.1
Karter, A.J.2
Yaffe, K.3
-
47
-
-
58149359256
-
Diffusion tensor imaging identifes defcits in white matter microstructure in subjects with type 1 diabetes that correlate with reduced neurocognitive function
-
Kodl CT, Franc DT, Rao JP et al. Diffusion tensor imaging identifes defcits in white matter microstructure in subjects with type 1 diabetes that correlate with reduced neurocognitive function. Diabetes 2008; 57:3083-3089.
-
(2008)
Diabetes
, vol.57
, pp. 3083-3089
-
-
Kodl, C.T.1
Franc, D.T.2
Rao, J.P.3
-
48
-
-
0242627597
-
Cerebrospinal fluid markers for prediction of Alzheimer's disease
-
Zetterberg LO,Wahlund K, Blennow. Cerebrospinal fluid markers for prediction of Alzheimer's disease. Neurosci Lett 2003; 352:67-69.
-
(2003)
Neurosci Lett
, vol.352
, pp. 67-69
-
-
Zetterberg, L.O.1
Wahlund, K.2
Blenno, W.3
-
49
-
-
32544435900
-
Association between CSF biomarkers and incipient Alzheimer's disease in patients with mild cognitive impairment: A follow-up study
-
Hansson H, Zetterberg P, Buchhave E et al. Association between CSF biomarkers and incipient Alzheimer's disease in patients with mild cognitive impairment: a follow-up study. Lancet Neurol 2006; 5:228-234.
-
(2006)
Lancet Neurol
, vol.5
, pp. 228-234
-
-
Hansson, H.1
Zetterberg, P.2
Buchhave, E.3
-
50
-
-
37349026227
-
Multicenter assessment of CSF-phosphorylated tau for the prediction ofconversion of MCI
-
Ewers M, Buerger K, Teipel SJ et al. Multicenter assessment of CSF-phosphorylated tau for the prediction ofconversion of MCI. Neurology 2007; 69:2205-2212.
-
(2007)
Neurology
, vol.69
, pp. 2205-2212
-
-
Ewers, M.1
Buerger, K.2
Teipel, S.J.3
-
51
-
-
44449143042
-
Progression of white matter hyperintensities and incidence of new lacunes over a 3-year period: The Leukoaraiosis and Disability study
-
Gouw AA, van der Flier WM, Fazekas F et al. Progression of white matter hyperintensities and incidence of new lacunes over a 3-year period: the Leukoaraiosis and Disability study. Stroke 2008; 39:1414-1420.
-
(2008)
Stroke
, vol.39
, pp. 1414-1420
-
-
Gouw, A.A.1
Van Der Flier, W.M.2
Fazekas, F.3
|