메뉴 건너뛰기




Volumn 23, Issue 10, 2012, Pages 1989-2006

Biomarkers and molecular probes for cell death imaging and targeted therapeutics

Author keywords

[No Author keywords available]

Indexed keywords

BIOMARKERS; CELL MEMBRANES; CLINICAL RESEARCH; ENZYME ACTIVITY; MAGNETIC RESONANCE IMAGING; MITOCHONDRIA; PHOSPHOLIPIDS; PROBES;

EID: 84867497719     PISSN: 10431802     EISSN: 15204812     Source Type: Journal    
DOI: 10.1021/bc3003309     Document Type: Review
Times cited : (119)

References (224)
  • 1
    • 0033593572 scopus 로고    scopus 로고
    • Cell death in development
    • DOI 10.1016/S0092-8674(00)80564-4
    • Vaux, D. L. and Korsmeyer, S. J. (1999) Cell death in development Cell 96, 245-254 (Pubitemid 29059354)
    • (1999) Cell , vol.96 , Issue.2 , pp. 245-254
    • Vaux, D.L.1    Korsmeyer, S.J.2
  • 2
    • 0028943734 scopus 로고
    • Apoptosis in the pathogenesis and treatment of disease
    • Thompson, C. B. (1995) Apoptosis in the pathogenesis and treatment of disease Science 267, 1456-1462
    • (1995) Science , vol.267 , pp. 1456-1462
    • Thompson, C.B.1
  • 4
    • 3543092021 scopus 로고    scopus 로고
    • Pathways of apoptotic and non-apoptotic death in tumour cells
    • Okada, H. and Mak, T. W. (2004) Pathways of apoptotic and non-apoptotic death in tumor cells Nat. Rev. Cancer 4, 592-603 (Pubitemid 39025054)
    • (2004) Nature Reviews Cancer , vol.4 , Issue.8 , pp. 592-603
    • Okada, H.1    Mak, T.W.2
  • 5
    • 14644407525 scopus 로고    scopus 로고
    • The role of apoptosis in cancer development and treatment response
    • DOI 10.1038/nrc1570
    • Brown, J. M. and Attardi, L. D. (2005) The role of apoptosis in cancer development and treatment response Nat. Rev. Cancer 5, 231-237 (Pubitemid 40314954)
    • (2005) Nature Reviews Cancer , vol.5 , Issue.3 , pp. 231-237
    • Brown, J.M.1    Attardi, L.D.2
  • 6
    • 33744988159 scopus 로고    scopus 로고
    • Autophagy: Is it cancer's friend or foe?
    • Marx, J. (2006) Autophagy: is it cancer's friend or foe? Science 312, 1160-1161
    • (2006) Science , vol.312 , pp. 1160-1161
    • Marx, J.1
  • 7
    • 84863230093 scopus 로고    scopus 로고
    • Control of nonapoptotic developmental cell death in Carnorhabditis elegans by a polyglutamine-repeat protein
    • Blum, E. S., Abraham, M. C., Yoshimura, S., Lu, Y., and Shaham, S. (2012) Control of nonapoptotic developmental cell death in Carnorhabditis elegans by a polyglutamine-repeat protein Science 335, 970-973
    • (2012) Science , vol.335 , pp. 970-973
    • Blum, E.S.1    Abraham, M.C.2    Yoshimura, S.3    Lu, Y.4    Shaham, S.5
  • 9
    • 3343013154 scopus 로고    scopus 로고
    • Phosphatidylserine exposure during early primary necrosis (oncosis) in JB6 cells as evidenced by immunogold labeling technique
    • DOI 10.1023/B:APPT.0000031452.75162.75
    • Krysko, O., de Ridder, L., and Cornelissen, M. (2004) Phosphatidylserine exposure during early primary necrosis (oncosis) in JB6 cells as evidenced by immunogold labeling technique Apoptosis 9, 495-500 (Pubitemid 38987586)
    • (2004) Apoptosis , vol.9 , Issue.4 , pp. 495-500
    • Krysko, O.1    De Ridder, L.2    Cornelissen, M.3
  • 10
    • 33749178260 scopus 로고    scopus 로고
    • Necrosis, a well-orchestrated form of cell demise: Signaling cascades, important mediators and concomitant immune response
    • Festjens, N., Vanden Berghe, T., and Vandenabeele, P. (2006) Necrosis, a well-orchestrated form of cell demise: signaling cascades, important mediators and concomitant immune response Biochim. Biophys. Acta 1757, 1371-1378
    • (2006) Biochim. Biophys. Acta , vol.1757 , pp. 1371-1378
    • Festjens, N.1    Vanden Berghe, T.2    Vandenabeele, P.3
  • 12
    • 34548188741 scopus 로고    scopus 로고
    • Self-eating and self-killing: Crosstalk between autophagy and apoptosis
    • DOI 10.1038/nrm2239, PII NRM2239
    • Maiuri, M. C., Zalckvar, E., Kimchi, A., and Kroemer, G. (2007) Self-eating and self-killing: crosstalk between autophagy and apoptosis Nat. Rev. Mol. Cell Biol. 8, 741-752 (Pubitemid 47312826)
    • (2007) Nature Reviews Molecular Cell Biology , vol.8 , Issue.9 , pp. 741-752
    • Maiuri, M.C.1    Zalckvar, E.2    Kimchi, A.3    Kroemer, G.4
  • 13
    • 46749127817 scopus 로고    scopus 로고
    • Tumor cell metabolism imaging
    • DOI 10.2967/jnumed.107.045930
    • Plathow, C. and Weber, W. A. (2008) Tumor cell metabolism imaging J. Nucl. Med. 49, 43S-63S (Pubitemid 351948036)
    • (2008) Journal of Nuclear Medicine , vol.49 , Issue.SUPPL.6
    • Plathow, C.1    Weber, W.A.2
  • 14
    • 34848881062 scopus 로고    scopus 로고
    • FLT: Measuring Tumor Cell Proliferation In Vivo With Positron Emission Tomography and 3′-Deoxy-3′[18F]Fluorothymidine
    • DOI 10.1053/j.semnuclmed.2007.08.001, PII S000129980700089X, Positron Emission Tomography With Fluorine-18 Agents Other Than Fluorodeoxyglucose
    • 18F]fluorothymidine Semin. Nucl. Med. 37, 429-439 (Pubitemid 47498262)
    • (2007) Seminars in Nuclear Medicine , vol.37 , Issue.6 , pp. 429-439
    • Salskov, A.1    Tammisetti, V.S.2    Grierson, J.3    Vesselle, H.4
  • 17
    • 46749092088 scopus 로고    scopus 로고
    • In vivo detection of apoptosis
    • DOI 10.2967/jnumed.107.045898
    • Blankenberg, F. G. (2008) In vivo detection of apoptosis J. Nucl. Med. 49, 81S-95S (Pubitemid 351948038)
    • (2008) Journal of Nuclear Medicine , vol.49 , Issue.SUPPL.6
    • Blankenberg, F.G.1
  • 19
    • 73449124065 scopus 로고    scopus 로고
    • In vivo apoptosis imaging agents and strategies
    • Zhao, M. (2009) In vivo apoptosis imaging agents and strategies Anti-Cancer Agent. Med. Chem. 9, 1018-1023
    • (2009) Anti-Cancer Agent. Med. Chem. , vol.9 , pp. 1018-1023
    • Zhao, M.1
  • 21
    • 84860190466 scopus 로고    scopus 로고
    • A molecular imaging primer: Modalities, imaging agents, and applications
    • James, M. L. and Gambhir, S. S. (2012) A molecular imaging primer: modalities, imaging agents, and applications Physiol. Rev. 92, 897-965
    • (2012) Physiol. Rev. , vol.92 , pp. 897-965
    • James, M.L.1    Gambhir, S.S.2
  • 22
    • 33846926304 scopus 로고    scopus 로고
    • Fluorescence imaging in vivo: recent advances
    • DOI 10.1016/j.copbio.2007.01.003, PII S0958166907000043
    • Rao, J., Dragulescu-Andrasi, A., and Yao, H. (2007) Fluorescence imaging in vivo: recent advances Curr. Opin. Biotechnol. 18, 17-25 (Pubitemid 46237739)
    • (2007) Current Opinion in Biotechnology , vol.18 , Issue.1 , pp. 17-25
    • Rao, J.1    Dragulescu-Andrasi, A.2    Yao, H.3
  • 23
    • 84858070141 scopus 로고    scopus 로고
    • Bioluminescence imaging: Looking beyond the light
    • Keyaerts, M., Caveliers, V., and Lahouette, T. (2012) Bioluminescence imaging: looking beyond the light Trends Mol. Med. 18, 164-172
    • (2012) Trends Mol. Med. , vol.18 , pp. 164-172
    • Keyaerts, M.1    Caveliers, V.2    Lahouette, T.3
  • 24
    • 73249116830 scopus 로고    scopus 로고
    • Pre-clinical whole-body fluorescence imaging: Review of instruments, methods and applications
    • Leblond, F., Davis, S. C., Valdés, P. A., and Pogue, B. W. (2010) Pre-clinical whole-body fluorescence imaging: review of instruments, methods and applications J. Photochem. Photobiol. B 98, 77-94
    • (2010) J. Photochem. Photobiol. B , vol.98 , pp. 77-94
    • Leblond, F.1    Davis, S.C.2    Valdés, P.A.3    Pogue, B.W.4
  • 26
    • 33846866033 scopus 로고    scopus 로고
    • Emerging concepts in molecular MRI
    • DOI 10.1016/j.copbio.2006.11.001, PII S0958166906001650
    • Sosnovik, D. E. and Weissleder, R. (2007) Emerging concepts in molecular MRI Curr. Opin. Biotechnol. 18, 4-10 (Pubitemid 46227964)
    • (2007) Current Opinion in Biotechnology , vol.18 , Issue.1 , pp. 4-10
    • Sosnovik, D.E.1    Weissleder, R.2
  • 27
    • 54249096028 scopus 로고    scopus 로고
    • Caspases in apoptosis and beyond
    • Li, J. and Yuan, J. (2008) Caspases in apoptosis and beyond Oncogene 27, 6194-6206
    • (2008) Oncogene , vol.27 , pp. 6194-6206
    • Li, J.1    Yuan, J.2
  • 28
    • 69249100500 scopus 로고    scopus 로고
    • Human caspases: Activation, specificity, and regulation
    • Pop, C. and Salvesen, G. S. (2009) Human caspases: activation, specificity, and regulation J. Biol. Chem. 284, 21777-21781
    • (2009) J. Biol. Chem. , vol.284 , pp. 21777-21781
    • Pop, C.1    Salvesen, G.S.2
  • 29
    • 10644282148 scopus 로고    scopus 로고
    • The protein structures that shape caspase activity, specificity, activation and inhibition
    • DOI 10.1042/BJ20041142
    • Fuentes-Prior, P. and Salvesen, G. S. (2004) The protein structures that shape caspase activity, specificity, activation and inhibition Biochem. J. 384, 201-232 (Pubitemid 39656233)
    • (2004) Biochemical Journal , vol.384 , Issue.2 , pp. 201-232
    • Fuentes-Prior, P.1    Salvesen, G.S.2
  • 31
    • 79957619035 scopus 로고    scopus 로고
    • High throughput ratio imaging to profile caspase activity: Potential application in multiparameter high content apoptosis analysis and drug screening
    • Joseph, J., Seervi, M., Sobhan, P. K., and Retnabai, S. T. (2011) High throughput ratio imaging to profile caspase activity: potential application in multiparameter high content apoptosis analysis and drug screening PLOS One 6, e20114
    • (2011) PLOS One , vol.6 , pp. 20114
    • Joseph, J.1    Seervi, M.2    Sobhan, P.K.3    Retnabai, S.T.4
  • 32
    • 73449109886 scopus 로고    scopus 로고
    • Fluorescence lifetime imaging microscopy of chemotherapy-induced apoptosis resistance in a syngenic mouse tumor model
    • Keese, M., Yagublu, V., Schwenke, K., Post, S., and Bastiaens, P. (2010) Fluorescence lifetime imaging microscopy of chemotherapy-induced apoptosis resistance in a syngenic mouse tumor model Int. J. Cancer 126, 104-113
    • (2010) Int. J. Cancer , vol.126 , pp. 104-113
    • Keese, M.1    Yagublu, V.2    Schwenke, K.3    Post, S.4    Bastiaens, P.5
  • 33
    • 64649101405 scopus 로고    scopus 로고
    • Activatable molecular systems using homologous near-infrared fluorescent probes for monitoring enzyme activities in vitro, in cellulo, and in vivo
    • Zhang, Z., Fan, J., Cheney, P. P., Berezin, M. Y., Edwards, W. B., Akers, W. J., Shen, D., Liang, K., Culver, J. P., and Achilefu, S. (2009) Activatable molecular systems using homologous near-infrared fluorescent probes for monitoring enzyme activities in vitro, in cellulo, and in vivo Mol. Pharmaceutics 6, 416-427
    • (2009) Mol. Pharmaceutics , vol.6 , pp. 416-427
    • Zhang, Z.1    Fan, J.2    Cheney, P.P.3    Berezin, M.Y.4    Edwards, W.B.5    Akers, W.J.6    Shen, D.7    Liang, K.8    Culver, J.P.9    Achilefu, S.10
  • 34
    • 34047219123 scopus 로고    scopus 로고
    • Biochemical and in vivo characterization of a small, membrane-permeant, caspase-activatable far-red fluorescent peptide for imaging apoptosis
    • DOI 10.1021/bi061959n
    • Bullock, K. E., Maxwell, D., Kesarwala, A. H., Gammon, S., Prior, J. L., Snow, M., Stanley, S., and Piwnica-Worms, D. (2007) Biochemical and in vivo characterization of a small, membrane-permeant, caspase-activatable far-red fluorescent peptide for imaging apoptosis Biochemistry 46, 4055-4065 (Pubitemid 46536069)
    • (2007) Biochemistry , vol.46 , Issue.13 , pp. 4055-4065
    • Bullok, K.E.1    Maxwell, D.2    Kesarwala, A.H.3    Gammon, S.4    Prior, J.L.5    Snow, M.6    Stanley, S.7    Piwnica-Worms, D.8
  • 35
    • 67249095097 scopus 로고    scopus 로고
    • Single-cell imaging of retinal ganglion cell apoptosis with a cell-penetrating, activatable peptide probe in an in vivo glaucoma model
    • Barnett, E. M., Zhang, X., Maxwell, D., Chang, Q., and Piwnica-Worms, D. (2009) Single-cell imaging of retinal ganglion cell apoptosis with a cell-penetrating, activatable peptide probe in an in vivo glaucoma model Proc. Natl. Acad. Sci. U.S.A. 106, 9391-9396
    • (2009) Proc. Natl. Acad. Sci. U.S.A. , vol.106 , pp. 9391-9396
    • Barnett, E.M.1    Zhang, X.2    Maxwell, D.3    Chang, Q.4    Piwnica-Worms, D.5
  • 36
    • 65249177729 scopus 로고    scopus 로고
    • An improved cell-penetrating, caspase-activatable, near-infrared fluorescent peptide for apoptosis imaging
    • Maxwell, D., Chang, Q., Zhang, X., Barnett, E. M., and Piwnica-Worms, D. (2009) An improved cell-penetrating, caspase-activatable, near-infrared fluorescent peptide for apoptosis imaging Bioconjugate Chem. 20, 702-709
    • (2009) Bioconjugate Chem. , vol.20 , pp. 702-709
    • Maxwell, D.1    Chang, Q.2    Zhang, X.3    Barnett, E.M.4    Piwnica-Worms, D.5
  • 37
    • 78649233643 scopus 로고    scopus 로고
    • Caspase sensitive gold nanoparticle for apoptosis imaging in live cells
    • Sun, I. C., Lee, S., Koo, H., Kwon, I. C., Choi, K., Ahn, C. H., and Kim, K. (2010) Caspase sensitive gold nanoparticle for apoptosis imaging in live cells Bioconjugate Chem. 21, 1939-1942
    • (2010) Bioconjugate Chem. , vol.21 , pp. 1939-1942
    • Sun, I.C.1    Lee, S.2    Koo, H.3    Kwon, I.C.4    Choi, K.5    Ahn, C.H.6    Kim, K.7
  • 38
    • 70449591292 scopus 로고    scopus 로고
    • Continuous imaging of plasmon rulers in live cells reveals early-stage caspase-3 activation at the single-molecule level
    • Jun, Y. W., Sheikholeslami, S., Hostetter, D. R., Tajon, C., Craik, C. S., and Alivisatos, A. P. (2009) Continuous imaging of plasmon rulers in live cells reveals early-stage caspase-3 activation at the single-molecule level Proc. Natl. Acad. Sci. U.S.A. 106, 17735-17740
    • (2009) Proc. Natl. Acad. Sci. U.S.A. , vol.106 , pp. 17735-17740
    • Jun, Y.W.1    Sheikholeslami, S.2    Hostetter, D.R.3    Tajon, C.4    Craik, C.S.5    Alivisatos, A.P.6
  • 39
    • 77953641803 scopus 로고    scopus 로고
    • The protease-mediated nucleus shuttles of subnanometer gold quantum dots for real-time monitoring of apoptotic cell death
    • Lin, S. Y., Chen, N. T., Sun, S. P., Chang, J. C., Wang, Y. C., Yang, C. S., and Lo, L. W. (2010) The protease-mediated nucleus shuttles of subnanometer gold quantum dots for real-time monitoring of apoptotic cell death J. Am. Chem. Soc. 132, 8309-8315
    • (2010) J. Am. Chem. Soc. , vol.132 , pp. 8309-8315
    • Lin, S.Y.1    Chen, N.T.2    Sun, S.P.3    Chang, J.C.4    Wang, Y.C.5    Yang, C.S.6    Lo, L.W.7
  • 40
    • 80052547703 scopus 로고    scopus 로고
    • Caspase-3 controlled assembly of nanoparticles for fluorescence turn on
    • Cao, C. Y., Chen, Y., Wu, F. Z., Deng, Y., and Liang, G. L. (2011) Caspase-3 controlled assembly of nanoparticles for fluorescence turn on Chem. Commun. 47, 10320-10322
    • (2011) Chem. Commun. , vol.47 , pp. 10320-10322
    • Cao, C.Y.1    Chen, Y.2    Wu, F.Z.3    Deng, Y.4    Liang, G.L.5
  • 43
    • 66149166193 scopus 로고    scopus 로고
    • Rational design of novel red-shifted BRET pairs: Platforms for real-time single-chain protease biosensors
    • Gammon, S. T., Villalobos, V. M., Roshal, M., Samrakandi, M., and Piwnica-Worms, D. (2009) Rational design of novel red-shifted BRET pairs: platforms for real-time single-chain protease biosensors Biotechnol. Prog. 25, 559-569
    • (2009) Biotechnol. Prog. , vol.25 , pp. 559-569
    • Gammon, S.T.1    Villalobos, V.M.2    Roshal, M.3    Samrakandi, M.4    Piwnica-Worms, D.5
  • 44
    • 35048844611 scopus 로고    scopus 로고
    • Cyclic Luciferase for Real-Time Sensing of Caspase-3 Activities in Living Mammals
    • DOI 10.1002/anie.200700538
    • Kanno, A., Yamanaka, Y., Hirano, H., Umezawa, Y., and Ozawa, T. (2007) Cyclic luciferase for real-time sensing of caspase-3 activities in living animals Angew. Chem., Int. Ed. 46, 7595-7599 (Pubitemid 47557005)
    • (2007) Angewandte Chemie - International Edition , vol.46 , Issue.40 , pp. 7595-7599
    • Kanno, A.1    Yamanaka, Y.2    Hirano, H.3    Umezawa, Y.4    Ozawa, T.5
  • 45
    • 53249155162 scopus 로고    scopus 로고
    • Monitoring caspase-3 activation with a multimodality imaging sensor in living subjects
    • Ray, P., De, A., Patel, M., and Gambhir, S. S. (2008) Monitoring caspase-3 activation with a multimodality imaging sensor in living subjects Clin. Cancer Res. 14, 5801-5809
    • (2008) Clin. Cancer Res. , vol.14 , pp. 5801-5809
    • Ray, P.1    De, A.2    Patel, M.3    Gambhir, S.S.4
  • 46
    • 79957895050 scopus 로고    scopus 로고
    • Multimodal in vivo imaging and blood monitoring of intrinsic and extrinsic apoptosis
    • Niers, J. M., Kerami, M., Pike, L., Lewandrowski, G., and Tannous, B. A. (2011) Multimodal in vivo imaging and blood monitoring of intrinsic and extrinsic apoptosis Mol. Therapy 19, 1090-1096
    • (2011) Mol. Therapy , vol.19 , pp. 1090-1096
    • Niers, J.M.1    Kerami, M.2    Pike, L.3    Lewandrowski, G.4    Tannous, B.A.5
  • 47
    • 42249103253 scopus 로고    scopus 로고
    • Noninvasive imaging of apoptosis and its application in cancer therapeutics
    • DOI 10.1158/1078-0432.CCR-07-0782
    • Coppola, J. M., Ross, B. D., and Rehemtulla, A. (2008) Noninvasive imaging of apoptosis and its application in cancer therapeutics Clin. Cancer Res. 14, 2492-2501 (Pubitemid 351551085)
    • (2008) Clinical Cancer Research , vol.14 , Issue.8 , pp. 2492-2501
    • Coppola, J.M.1    Ross, B.D.2    Rehemtulla, A.3
  • 55
    • 0036882396 scopus 로고    scopus 로고
    • Irreversible inhibitors of serine, cysteine, and threonine proteases
    • Powers, J. C., Asgian, J. L., Ekici, O. D., and James, K. E. (2002) Irreversible inhibitors of serine, cysteine, and threonine proteases Chem. Rev. 102, 4639-4750
    • (2002) Chem. Rev. , vol.102 , pp. 4639-4750
    • Powers, J.C.1    Asgian, J.L.2    Ekici, O.D.3    James, K.E.4
  • 57
  • 58
    • 26444537963 scopus 로고    scopus 로고
    • Neural stem cell differentiation is dependent upon endogenous caspase 3 activity
    • DOI 10.1096/fj.04-2981fje
    • Fernando, P., Brunette, S., and Megeney, L. A. (2005) Neural stem cell differentiation is dependent upon endogenous Caspase 3 activity FASEB J. 19, 1671-1673 (Pubitemid 41429525)
    • (2005) FASEB Journal , vol.19 , Issue.12 , pp. 1671-1673
    • Fernando, P.1    Brunette, S.2    Megeney, L.A.3
  • 59
    • 58149464289 scopus 로고    scopus 로고
    • The Jekyll and Hyde functions of caspases
    • Yi, C. H. and Yuan, J. (2009) The Jekyll and Hyde functions of caspases Dev. Cell 16, 21-34
    • (2009) Dev. Cell , vol.16 , pp. 21-34
    • Yi, C.H.1    Yuan, J.2
  • 61
    • 0037879052 scopus 로고    scopus 로고
    • m) in apoptosis; an update
    • DOI 10.1023/A:1022945107762
    • m) in apoptosis; an update Apoptosis 8, 115-128 (Pubitemid 36553052)
    • (2003) Apoptosis , vol.8 , Issue.2 , pp. 115-128
    • Ly, J.D.1    Grubb, D.R.2    Lawen, A.3
  • 63
    • 77957950297 scopus 로고    scopus 로고
    • Imaging the life and death of tumors in living subjects: Preclinical PET imaging of proliferation and apoptosis
    • Nguyen, Q. D. and Aboagye, E. O. (2010) Imaging the life and death of tumors in living subjects: preclinical PET imaging of proliferation and apoptosis Integr. Biol. 2, 483-495
    • (2010) Integr. Biol. , vol.2 , pp. 483-495
    • Nguyen, Q.D.1    Aboagye, E.O.2
  • 66
    • 84864872162 scopus 로고    scopus 로고
    • An inhibitor of glutathione S-transferase omega 1 that selectively targets apoptotic cells
    • Pace, N. J., Pimental, D. R., and Weerapana, E. (2012) An inhibitor of glutathione S-transferase omega 1 that selectively targets apoptotic cells Angew. Chem., Int. Ed. 51, 8365-8368
    • (2012) Angew. Chem., Int. Ed. , vol.51 , pp. 8365-8368
    • Pace, N.J.1    Pimental, D.R.2    Weerapana, E.3
  • 68
    • 34848917111 scopus 로고    scopus 로고
    • The La autoantigen is a malignancy-associated cell death target that is induced by DNA-damaging drugs
    • DOI 10.1158/1078-0432.CCR-07-0922
    • Al-Ejeh, F., Darby, J. M., and Brown, M. P. (2007) The La autoantigen is a malignancy-associated cell death target that is induced by DNA-damaging drugs Clin. Cancer Res. 13, 5509s-5518s (Pubitemid 47510381)
    • (2007) Clinical Cancer Research , vol.13 , Issue.18
    • Al-Ejeh, F.1    Darby, J.M.2    Brown, M.P.3
  • 69
    • 34848886657 scopus 로고    scopus 로고
    • In vivo targeting of dead tumor cells in a murine tumor model using a monoclonal antibody specific for the La autoantigen
    • DOI 10.1158/1078-0432.CCR-07-0964
    • Al-Ejeh, F., Darby, J. M., Pensa, K., Diener, K. R., Hayball, J. D., and Brown, M. P. (2007) In vivo targeting of dead tumor cells in a murine tumor model using a monoclonal antibody specific for the La autoantigen Clin. Cancer Res. 13, 5519s-5527s (Pubitemid 47510382)
    • (2007) Clinical Cancer Research , vol.13 , Issue.18
    • Al-Ejeh, F.1    Darby, J.M.2    Pensa, K.3    Diener, K.R.4    Hayball, J.D.5    Brown, M.P.6
  • 70
    • 84864279733 scopus 로고    scopus 로고
    • APOMAB, a La-specific monoclonal antibody, detects the apoptotic tumor response to life-prolonging and DNA-damaging chemotherapy
    • Al-Ejeh, F., Darby, J. M., Tsopelas, C., Smyth, D., Manavis, J., and Brown, M. P. (2009) APOMAB, a La-specific monoclonal antibody, detects the apoptotic tumor response to life-prolonging and DNA-damaging chemotherapy PLoS ONE 4, e4558
    • (2009) PLoS ONE , vol.4 , pp. 4558
    • Al-Ejeh, F.1    Darby, J.M.2    Tsopelas, C.3    Smyth, D.4    Manavis, J.5    Brown, M.P.6
  • 73
    • 0031149132 scopus 로고    scopus 로고
    • Exposure of phosphatidylethanolamine on the surface of apoptotic cells
    • DOI 10.1006/excr.1997.3521
    • Emoto, K., Toyama-Sorimachi, N., Karasuyama, H., Inoue, K., and Umeda, M. (1997) Exposure of phosphatidylethanolamine on the surface of apoptotic cells Exp. Cell Res. 232, 430-434 (Pubitemid 27194059)
    • (1997) Experimental Cell Research , vol.232 , Issue.2 , pp. 430-434
    • Emoto, K.1    Toyama-Sorimachi, N.2    Karasuyama, H.3    Inoue, K.4    Umeda, M.5
  • 75
    • 3042791860 scopus 로고    scopus 로고
    • Preparation of F-18 labeled annexin V: A potential PET radiopharmaceutical for imaging cell death
    • DOI 10.1016/j.nucmedbio.2004.02.007, PII S0969805104000459
    • Toretsky, J., Levenson, A., Weinberg, I. N., Tait, J. F., Uren, A., and Mease, R. C. (2004) Preparation of F-18 labeled annexin V: a potential PET radiopharmaceutical for imaging cell death Nucl. Med. Biol. 31, 747-752 (Pubitemid 38887756)
    • (2004) Nuclear Medicine and Biology , vol.31 , Issue.6 , pp. 747-752
    • Toretsky, J.1    Levenson, A.2    Weinberg, I.N.3    Tait, J.F.4    Uren, A.5    Mease, R.C.6
  • 76
    • 73449117977 scopus 로고    scopus 로고
    • Molecular MRI of cardiomyocyte apoptosis with simultaneous delayed enhancement MRI distinguishes apoptotic and necrotic myocytes in vivo: Potential for midmyocardial salvage in acute ischemia
    • Sosnovik, D. E., Garanger, E., Aikawa, E., Nahrendorf, M., Figuiredo, J. L., Dai, G., Reynolds, F., Rosenzweig, A., Weissleder, R., and Josephson, L. (2009) Molecular MRI of cardiomyocyte apoptosis with simultaneous delayed enhancement MRI distinguishes apoptotic and necrotic myocytes in vivo: potential for midmyocardial salvage in acute ischemia Circ. Cardiovasc. Imaging 2, 460-467
    • (2009) Circ. Cardiovasc. Imaging , vol.2 , pp. 460-467
    • Sosnovik, D.E.1    Garanger, E.2    Aikawa, E.3    Nahrendorf, M.4    Figuiredo, J.L.5    Dai, G.6    Reynolds, F.7    Rosenzweig, A.8    Weissleder, R.9    Josephson, L.10
  • 79
    • 78651328507 scopus 로고    scopus 로고
    • Radiotracers for noninvasive molecular imaging of tumor cell death
    • Kapty, J., Murray, D., and Mercer, J. (2010) Radiotracers for noninvasive molecular imaging of tumor cell death Cancer Biother. Radio. 25, 615-628
    • (2010) Cancer Biother. Radio. , vol.25 , pp. 615-628
    • Kapty, J.1    Murray, D.2    Mercer, J.3
  • 82
    • 79851482376 scopus 로고    scopus 로고
    • Apoptosis imaging: Beyond annexin v
    • Niu, G. and Chen, X. (2010) Apoptosis imaging: beyond annexin V J. Nucl. Med. 51, 1659-1662
    • (2010) J. Nucl. Med. , vol.51 , pp. 1659-1662
    • Niu, G.1    Chen, X.2
  • 83
    • 84876030360 scopus 로고    scopus 로고
    • Beyond annexin V: Fluorescence response of cellular membranes to apoptosis
    • 10.1007/s10616-012-9481-y
    • Demchenko, A. P. (2012) Beyond annexin V: fluorescence response of cellular membranes to apoptosis Cytotechnology 10.1007/s10616-012-9481-y
    • (2012) Cytotechnology
    • Demchenko, A.P.1
  • 84
    • 73449098139 scopus 로고    scopus 로고
    • Molecular imaging of apoptosis with radio-labeled Annexin A5 focused on the evaluation of tumor response to chemotherapy
    • Kuge, Y., Zhao, S., Takei, T., and Tamaki, N. (2009) Molecular imaging of apoptosis with radio-labeled Annexin A5 focused on the evaluation of tumor response to chemotherapy Anti-Cancer Agent. Med. Chem. 9, 1003-1011
    • (2009) Anti-Cancer Agent. Med. Chem. , vol.9 , pp. 1003-1011
    • Kuge, Y.1    Zhao, S.2    Takei, T.3    Tamaki, N.4
  • 87
    • 70449133429 scopus 로고    scopus 로고
    • 99mTc-labeled Annexin A5 variant for non-invasive SPECT imaging of cell death in liver, spleen, and prostate
    • 99mTc-labeled Annexin A5 variant for non-invasive SPECT imaging of cell death in liver, spleen, and prostate Pharm. Res. 26, 2647-2656
    • (2009) Pharm. Res. , vol.26 , pp. 2647-2656
    • Greupink, R.1    Sio, C.F.2    Ederveen, A.3    Orsel, J.4
  • 97
    • 78751547461 scopus 로고    scopus 로고
    • Engineered Annexin A5 variants have impaired cell entry for molecular imaging of apoptosis using pretargeting strategies
    • Ungethüm, L., Kenis, H., Nicolaes, G. A., Autin, L., Stoilova-McPhie, S., and Reutelingsperger, C. P. (2011) Engineered Annexin A5 variants have impaired cell entry for molecular imaging of apoptosis using pretargeting strategies J. Biol. Chem. 286, 1903-1910
    • (2011) J. Biol. Chem. , vol.286 , pp. 1903-1910
    • Ungethüm, L.1    Kenis, H.2    Nicolaes, G.A.3    Autin, L.4    Stoilova-Mcphie, S.5    Reutelingsperger, C.P.6
  • 102
    • 77952578519 scopus 로고    scopus 로고
    • Comparison of the C2A domain of Synaptotagmin-I and Annexin-V as probes for detecting cell death
    • Alam, I. S., Neves, A. A., Witney, T. H., Boren, J., and Brindle, K. M. (2010) Comparison of the C2A domain of Synaptotagmin-I and Annexin-V as probes for detecting cell death Bioconjugate Chem. 21, 884-891
    • (2010) Bioconjugate Chem. , vol.21 , pp. 884-891
    • Alam, I.S.1    Neves, A.A.2    Witney, T.H.3    Boren, J.4    Brindle, K.M.5
  • 103
    • 38149094836 scopus 로고    scopus 로고
    • Membrane phosphatidylserine regulates surface charge and protein localization
    • Yeung, T., Gilbert, G. E., Shi, J., Silvius, J., Kapus, A., and Grinstein, S. (2008) Membrane phosphatidylserine regulates surface charge and protein localization Science 319, 210-213
    • (2008) Science , vol.319 , pp. 210-213
    • Yeung, T.1    Gilbert, G.E.2    Shi, J.3    Silvius, J.4    Kapus, A.5    Grinstein, S.6
  • 104
    • 78651314081 scopus 로고    scopus 로고
    • Lactadherin functions as a probe for phosphatidylserine exposure and as an anticoagulant in the study of stored platelets
    • Hou, J., Fu, Y., Zhou, J., Li, W., Xie, R., Cao, F., Gilbert, G. E., and Shi, J. (2011) Lactadherin functions as a probe for phosphatidylserine exposure and as an anticoagulant in the study of stored platelets Vox Sanguins 100, 187-195
    • (2011) Vox Sanguins , vol.100 , pp. 187-195
    • Hou, J.1    Fu, Y.2    Zhou, J.3    Li, W.4    Xie, R.5    Cao, F.6    Gilbert, G.E.7    Shi, J.8
  • 110
    • 84861526365 scopus 로고    scopus 로고
    • Development of a magnetic resonance imaging protocol for the characterization of atherosclerotic plaque by using vascular cell adhesion molecule-1 and apoptosis-targeted ultrasmall superparamagnetic iron oxide derivatives
    • Burtea, C., Ballet, S., Laurent, S., Rousseaux, O., Dencausse, A., Gonzalez, W., Port, M., Corot, C., Vander Elst, L., and Muller, R. N. (2012) Development of a magnetic resonance imaging protocol for the characterization of atherosclerotic plaque by using vascular cell adhesion molecule-1 and apoptosis-targeted ultrasmall superparamagnetic iron oxide derivatives Arterioscler. Thromb. Vasc. Biol. 32, e36-348
    • (2012) Arterioscler. Thromb. Vasc. Biol. , vol.32 , pp. 36-348
    • Burtea, C.1    Ballet, S.2    Laurent, S.3    Rousseaux, O.4    Dencausse, A.5    Gonzalez, W.6    Port, M.7    Corot, C.8    Vander Elst, L.9    Muller, R.N.10
  • 111
    • 54049124091 scopus 로고    scopus 로고
    • Discovery of a phosphatidylserine-recognizing peptide and its utility in molecular imaging of tumour apoptosis
    • Thapa, N., Kim, S., So, I. S., Lee, B. H., Kwon, I. C., Choi, K., and Kim, I. S. (2008) Discovery of a phosphatidylserine-recognizing peptide and its utility in molecular imaging of tumour apoptosis J. Cell. Mol. Med. 12, 1649-1660
    • (2008) J. Cell. Mol. Med. , vol.12 , pp. 1649-1660
    • Thapa, N.1    Kim, S.2    So, I.S.3    Lee, B.H.4    Kwon, I.C.5    Choi, K.6    Kim, I.S.7
  • 112
    • 37649016975 scopus 로고    scopus 로고
    • Targeting phosphatidylserine on apoptotic cells with phages and peptides selected from a bacteriophage display library
    • Shao, R., Xiong, C., Wen, X., Gelovani, J. G., and Li, C. (2007) Targeting phosphatidylserine on apoptotic cells with phages and peptides selected from a bacteriophage display library Mol. Imaging 6, 417-426
    • (2007) Mol. Imaging , vol.6 , pp. 417-426
    • Shao, R.1    Xiong, C.2    Wen, X.3    Gelovani, J.G.4    Li, C.5
  • 113
    • 79952776184 scopus 로고    scopus 로고
    • Peptide-based imaging agents targeting phosphatidylserine for the detection of apoptosis
    • Xiong, C., Brewer, K., Song, S., Zhang, R., Lu, W., Wen, X., and Li, C. (2011) Peptide-based imaging agents targeting phosphatidylserine for the detection of apoptosis J. Med. Chem. 54, 1825-1835
    • (2011) J. Med. Chem. , vol.54 , pp. 1825-1835
    • Xiong, C.1    Brewer, K.2    Song, S.3    Zhang, R.4    Lu, W.5    Wen, X.6    Li, C.7
  • 114
    • 80053330216 scopus 로고    scopus 로고
    • Cofactor-free detection of phosphatidylserine with cyclic peptides mimicking lactadherin
    • Zheng, H., Wang, F., Wang, Q., and Gao, J. (2011) Cofactor-free detection of phosphatidylserine with cyclic peptides mimicking lactadherin J. Am. Chem. Soc. 133, 15280-15283
    • (2011) J. Am. Chem. Soc. , vol.133 , pp. 15280-15283
    • Zheng, H.1    Wang, F.2    Wang, Q.3    Gao, J.4
  • 115
    • 33645397600 scopus 로고    scopus 로고
    • Fluorescent detection of apoptotic cells by using zinc coordination complexes with a selective affinity for membrane surfaces enriched with phosphatidylserine
    • Hanshaw, R. G., Lakshmi, C., Lambert, T. N., and Smith, B. D. (2005) Fluorescent detection of apoptotic cells by using zinc coordination complexes with a selective affinity for membrane surfaces enriched with phosphatidylserine ChemBioChem 12, 2214-2220
    • (2005) ChemBioChem , vol.12 , pp. 2214-2220
    • Hanshaw, R.G.1    Lakshmi, C.2    Lambert, T.N.3    Smith, B.D.4
  • 116
    • 74849090694 scopus 로고    scopus 로고
    • Optical imaging of mammary and prostate tumors in living animals using a synthetic near infrared zinc(II)-dipicolylamine probe for anionic cell surfaces
    • Smith, B. A., Akers, W. J., Leevy, W. M., Lampkins, A. J., Xiao, S., Wolter, W., Suckow, M. A., Achilefu, S., and Smith, B. D. (2010) Optical imaging of mammary and prostate tumors in living animals using a synthetic near infrared zinc(II)-dipicolylamine probe for anionic cell surfaces J. Am. Chem. Soc. 132, 67-69
    • (2010) J. Am. Chem. Soc. , vol.132 , pp. 67-69
    • Smith, B.A.1    Akers, W.J.2    Leevy, W.M.3    Lampkins, A.J.4    Xiao, S.5    Wolter, W.6    Suckow, M.A.7    Achilefu, S.8    Smith, B.D.9
  • 118
    • 80051546958 scopus 로고    scopus 로고
    • In vivo targeting of cell death using a synthetic fluorescent molecular probe
    • Smith, B. A., Xiao, S., Wolter, W., Wheeler, J., Suckow, M. A., and Smith, B. D. (2011) In vivo targeting of cell death using a synthetic fluorescent molecular probe Apoptosis 16, 722-731
    • (2011) Apoptosis , vol.16 , pp. 722-731
    • Smith, B.A.1    Xiao, S.2    Wolter, W.3    Wheeler, J.4    Suckow, M.A.5    Smith, B.D.6
  • 120
    • 80053352705 scopus 로고    scopus 로고
    • Near-infrared fluorescent zinc-dipicolylamine: A new molecular imaging probe to monitor the efficiency of chemotherapy
    • Hu, S., Chai, W., Liu, Z., Yin, C., and Lei, M. (2011) Near-infrared fluorescent zinc-dipicolylamine: a new molecular imaging probe to monitor the efficiency of chemotherapy J. Cent. South Univ. Med. Sci. 36, 760-764
    • (2011) J. Cent. South Univ. Med. Sci. , vol.36 , pp. 760-764
    • Hu, S.1    Chai, W.2    Liu, Z.3    Yin, C.4    Lei, M.5
  • 122
    • 79957491676 scopus 로고    scopus 로고
    • Synthesis and preliminary evaluation of radiolabeled Bis(Zinc(II)- Dipicolylamine) coordination complexes as cell death imaging agents
    • Wyffels, L., Gray, B. D., Barber, C., Moore, S. K., Woolfenden, J. M., Pak, K. Y., and Liu, Z. (2011) Synthesis and preliminary evaluation of radiolabeled Bis(Zinc(II)-Dipicolylamine) coordination complexes as cell death imaging agents Bioorg. Med. Chem. 19, 3425-3433
    • (2011) Bioorg. Med. Chem. , vol.19 , pp. 3425-3433
    • Wyffels, L.1    Gray, B.D.2    Barber, C.3    Moore, S.K.4    Woolfenden, J.M.5    Pak, K.Y.6    Liu, Z.7
  • 123
    • 80052529282 scopus 로고    scopus 로고
    • Targeting of anionic membrane species by lanthanide(III) complexes: Towards improved MRI contrast agents for apoptosis
    • Surman, A. J., Kenny, G. D., Kumar, D. K., Bell, J. D., Casey, D. R., and Vilar, R. (2011) Targeting of anionic membrane species by lanthanide(III) complexes: towards improved MRI contrast agents for apoptosis Chem. Commun. 47, 10245-10247
    • (2011) Chem. Commun. , vol.47 , pp. 10245-10247
    • Surman, A.J.1    Kenny, G.D.2    Kumar, D.K.3    Bell, J.D.4    Casey, D.R.5    Vilar, R.6
  • 124
    • 33645419086 scopus 로고    scopus 로고
    • A fluorescent nanosensor for apoptotic cells
    • Quinti, L., Weissleder, R., and Tung, C. H. (2006) A fluorescent nanosensor for apoptotic cells Nano Lett. 6, 488-490
    • (2006) Nano Lett. , vol.6 , pp. 488-490
    • Quinti, L.1    Weissleder, R.2    Tung, C.H.3
  • 126
    • 84855230886 scopus 로고    scopus 로고
    • Lantibiotics as probes for phosphatidylethanolamine
    • Zhao, M. (2011) Lantibiotics as probes for phosphatidylethanolamine Amino Acids 41, 1071-1079
    • (2011) Amino Acids , vol.41 , pp. 1071-1079
    • Zhao, M.1
  • 127
    • 48749103305 scopus 로고    scopus 로고
    • 99mTc-Labeled Duramycin as a novel phosphatidylethanolamine- binding molecular probe
    • 99mTc-Labeled Duramycin as a novel phosphatidylethanolamine-binding molecular probe J. Nucl. Med. 49, 1345-1352
    • (2008) J. Nucl. Med. , vol.49 , pp. 1345-1352
    • Zhao, M.1    Li, Z.2    Bugenhagen, S.3
  • 128
    • 52049088939 scopus 로고    scopus 로고
    • Coincident exposure of phosphatidylethanolamine and anionic phospholipids on the surface of irradiated cells
    • Marconescu, A. and Thorpe, P. E. (2008) Coincident exposure of phosphatidylethanolamine and anionic phospholipids on the surface of irradiated cells Biochim. Biophys. Acta 1778, 2217-2224
    • (2008) Biochim. Biophys. Acta , vol.1778 , pp. 2217-2224
    • Marconescu, A.1    Thorpe, P.E.2
  • 129
    • 79953695111 scopus 로고    scopus 로고
    • Increased exposure of phosphatidylethanolamine on the surface of tumor vascular endothelium
    • Stafford, J. H. and Thorpe, P. E. (2011) Increased exposure of phosphatidylethanolamine on the surface of tumor vascular endothelium Neoplasia 13, 299-308
    • (2011) Neoplasia , vol.13 , pp. 299-308
    • Stafford, J.H.1    Thorpe, P.E.2
  • 130
    • 84863386988 scopus 로고    scopus 로고
    • Human CD300a binds to phosphatidylethanolamine and phosphatidylserine, and modulates the phagocytosis of dead cells
    • Simhadri, V. R., Andersen, J. F., Calvo, E., Choi, S. C., Coligan, J. E., and Borrego, F. (2012) Human CD300a binds to phosphatidylethanolamine and phosphatidylserine, and modulates the phagocytosis of dead cells Blood 119, 2799-2809
    • (2012) Blood , vol.119 , pp. 2799-2809
    • Simhadri, V.R.1    Andersen, J.F.2    Calvo, E.3    Choi, S.C.4    Coligan, J.E.5    Borrego, F.6
  • 132
    • 0036829110 scopus 로고    scopus 로고
    • Increased exposure of anionic phospholipids on the surface of tumor blood vessels
    • Ran, S., Downes, A., and Thorpe, P. E. (2002) Increased exposure of anionic phospholipids on the surface of tumor blood vessels Cancer Res. 62, 6132-6140 (Pubitemid 35244462)
    • (2002) Cancer Research , vol.62 , Issue.21 , pp. 6132-6140
    • Ran, S.1    Downes, A.2    Thorpe, P.E.3
  • 133
    • 80255124055 scopus 로고    scopus 로고
    • In search of a novel target - Phosphatidylserine exposed by non-apoptotic tumor cells and metastases of malignancies with poor treatment efficacy
    • Riedl, S., Rinner, B., Asslaber, M., Schaider, H., Walzer, S., Novak, A., Lohner, K., and Zweytick, D. (2011) In search of a novel target - phosphatidylserine exposed by non-apoptotic tumor cells and metastases of malignancies with poor treatment efficacy Biochim. Biophys. Acta 1808, 2638-2645
    • (2011) Biochim. Biophys. Acta , vol.1808 , pp. 2638-2645
    • Riedl, S.1    Rinner, B.2    Asslaber, M.3    Schaider, H.4    Walzer, S.5    Novak, A.6    Lohner, K.7    Zweytick, D.8
  • 134
    • 69849100452 scopus 로고    scopus 로고
    • Tumor-derived microvesicles modulate the establishment of metastatic melanoma in a phosphatidylserine-dependent manner
    • Lima, L. G., Chammas, R., Monteiro, R. Q., Moreira, M. E., and Barcinski, M. A. (2009) Tumor-derived microvesicles modulate the establishment of metastatic melanoma in a phosphatidylserine-dependent manner Cancer Lett. 283, 168-175
    • (2009) Cancer Lett. , vol.283 , pp. 168-175
    • Lima, L.G.1    Chammas, R.2    Monteiro, R.Q.3    Moreira, M.E.4    Barcinski, M.A.5
  • 135
    • 2442707797 scopus 로고    scopus 로고
    • Nucleosomes are exposed at the cell surface in apoptosis
    • Radic, M., Marion, T., and Monestier, M. (2004) Nucleosomes are exposed at the cell surface in apoptosis J. Immunol. 172, 6692-6700 (Pubitemid 38669105)
    • (2004) Journal of Immunology , vol.172 , Issue.11 , pp. 6692-6700
    • Radic, M.1    Marion, T.2    Monestier, M.3
  • 136
    • 49949087224 scopus 로고    scopus 로고
    • Caspase-mediated changes in Histone H1 in early apoptosis: Prolonged caspase activation in devloping olfactory sensory neurons
    • Ohsawa, S., Hamada, S., Yoshida, H., and Miura, M. (2008) Caspase-mediated changes in Histone H1 in early apoptosis: prolonged caspase activation in devloping olfactory sensory neurons Cell Death Differ. 15, 1429-1439
    • (2008) Cell Death Differ. , vol.15 , pp. 1429-1439
    • Ohsawa, S.1    Hamada, S.2    Yoshida, H.3    Miura, M.4
  • 138
    • 84861478661 scopus 로고    scopus 로고
    • Molecular imaging of cell death in an experimental model of Parkinson's disease with a novel apoptosis-targeting peptide
    • Lee, M. J., Wang, K., Kim, I. S., Lee, B. H., and Han, H. S. (2012) Molecular imaging of cell death in an experimental model of Parkinson's disease with a novel apoptosis-targeting peptide Mol. Imaging Biol. 14, 147-155
    • (2012) Mol. Imaging Biol. , vol.14 , pp. 147-155
    • Lee, M.J.1    Wang, K.2    Kim, I.S.3    Lee, B.H.4    Han, H.S.5
  • 140
    • 46349091973 scopus 로고    scopus 로고
    • Targeting cell death in vivo in experimental traumatic brain injury by a novel molecular probe
    • DOI 10.1089/neu.2007.0341
    • Reshef, A., Shirvan, A., Shohami, E., Grimberg, H., Levin, G., Cohen, A., Trembovier, V., and Ziv, I. (2008) Targeting cell death in vivo in experimental traumatic brain injury by a novel molecular probe J. Neurotrauma 25, 569-580 (Pubitemid 351918433)
    • (2008) Journal of Neurotrauma , vol.25 , Issue.6 , pp. 569-580
    • Reshef, A.1    Shirvan, A.2    Shohami, E.3    Grimberg, H.4    Levin, G.5    Cohen, A.6    Trembovler, V.7    Ziv, I.8
  • 142
    • 44649187419 scopus 로고    scopus 로고
    • Synthesis, biological evaluation and radiochemical labeling of a dansylhydrazone derivative as a potential imaging agent for apoptosis
    • DOI 10.1016/j.bmcl.2008.05.002, PII S0960894X0800485X
    • Zeng, W., Yao, M. L., Townsend, D., Kabalka, G., Wall, J., Le Puil, M., Biggerstaff, J., and Miao, W. (2008) Synthesis, biological evaluation and radiochemical labeling of a dansylhydrazone derivative as a potential imaging agent for apoptosis Bioorg. Med. Chem. Lett. 18, 3573-3577 (Pubitemid 351787557)
    • (2008) Bioorganic and Medicinal Chemistry Letters , vol.18 , Issue.12 , pp. 3573-3577
    • Zeng, W.1    Yao, M.-l.2    Townsend, D.3    Kabalka, G.4    Wall, J.5    Le Puil, M.6    Biggerstaff, J.7    Miao, W.8
  • 144
    • 67649109027 scopus 로고    scopus 로고
    • From the Gla doman to a novel small-molecule detector of apoptosis
    • Cohen, A., Shirvan, A., Levin, G., Grimberg, H., Reshef, A., and Ziv, I. (2009) From the Gla doman to a novel small-molecule detector of apoptosis Cell Res. 19, 625-637
    • (2009) Cell Res. , vol.19 , pp. 625-637
    • Cohen, A.1    Shirvan, A.2    Levin, G.3    Grimberg, H.4    Reshef, A.5    Ziv, I.6
  • 150
    • 77955133412 scopus 로고    scopus 로고
    • Hoechst-IR: An imaging agent that detects necrotic tissue in vivo by binding extracellular DNA
    • Dasari, M., Lee, S., Sy, J., Kim, D., Lee, S., Brown, M., Davis, M., and Murthy, N. (2010) Hoechst-IR: an imaging agent that detects necrotic tissue in vivo by binding extracellular DNA Org. Lett. 12, 3300-3303
    • (2010) Org. Lett. , vol.12 , pp. 3300-3303
    • Dasari, M.1    Lee, S.2    Sy, J.3    Kim, D.4    Lee, S.5    Brown, M.6    Davis, M.7    Murthy, N.8
  • 153
    • 0026540818 scopus 로고
    • Comparative evaluation of several DNA binding dyes in the detection of apoptosis-associated chromatin degradation by flow cytometry
    • Telford, W. G., King, L. E., and Fraker, P. J. (1992) Comparative evaluation of several DNA binding dyes in the detection of apoptosis-associated chromatin degradation by flow cytometry Cytometry 13, 137-143
    • (1992) Cytometry , vol.13 , pp. 137-143
    • Telford, W.G.1    King, L.E.2    Fraker, P.J.3
  • 157
    • 33751156256 scopus 로고
    • Spectroscopic properties of hypericin in solution and at surface
    • Wynn, J. L. and Cotton, T. M. (1995) Spectroscopic properties of hypericin in solution and at surface J. Phys. Chem. 99, 4317-4323
    • (1995) J. Phys. Chem. , vol.99 , pp. 4317-4323
    • Wynn, J.L.1    Cotton, T.M.2
  • 158
    • 43849086838 scopus 로고    scopus 로고
    • Hypericin as a marker for determination of tissue viability after radiofrequency ablation in a murine liver tumor model
    • Van de Putte, M., Wang, H., Chen., F., De Witte, P. A., and Ni, Y. (2008) Hypericin as a marker for determination of tissue viability after radiofrequency ablation in a murine liver tumor model Oncol. Rep. 19, 927-932 (Pubitemid 351802661)
    • (2008) Oncology Reports , vol.19 , Issue.4 , pp. 927-932
    • Van De Putte, M.1    Wang, H.2    Chen, F.3    De Witte, P.A.M.4    Ni, Y.5
  • 163
    • 43849086304 scopus 로고    scopus 로고
    • Exploration of the mechanism underlying the tumor necrosis avidity of hypericin
    • Van de Putte, M., Ni, Y., and de Witte, P. A. (2008) Exploration of the mechanism underlying the tumor necrosis avidity of hypericin Oncol. Rep. 19, 921-926 (Pubitemid 351802660)
    • (2008) Oncology Reports , vol.19 , Issue.4 , pp. 921-926
    • Van De Putte, M.1    Ni, Y.2    De Witte, P.A.M.3
  • 165
    • 42449123761 scopus 로고    scopus 로고
    • Expansion and evolution of cell death programmes
    • DOI 10.1038/nrm2393, PII NRM2393
    • Degterev, A. and Yuan, J. (2008) Expansion and evolution of cell death programmes Nat. Rev. Mol. Cell Biol. 9, 378-390 (Pubitemid 351574200)
    • (2008) Nature Reviews Molecular Cell Biology , vol.9 , Issue.5 , pp. 378-390
    • Degterev, A.1    Yuan, J.2
  • 168
    • 0032951071 scopus 로고    scopus 로고
    • In vivo imaging of tumors with protease-activated near-infrared fluorescent probes
    • DOI 10.1038/7933
    • Weissleder, R., Tung, C. H., Mahmood, U., and Bogdanov, A., Jr. (1999) In vivo imaging of tumors with protease-activated near-infrared fluorescent probes Nat. Biotechnol. 17, 375-378 (Pubitemid 29166041)
    • (1999) Nature Biotechnology , vol.17 , Issue.4 , pp. 375-378
    • Weissleder, R.1    Tung, C.-H.2    Mahmood, U.3    Bogdanov Jr., A.4
  • 170
    • 1642576236 scopus 로고    scopus 로고
    • Cathepsin B Mediates Caspase-Independent Cell Death Induced by Microtubule Stabilizing Agents in Non-Small Cell Lung Cancer Cells
    • DOI 10.1158/0008-5472.CAN-03-3060
    • Bröker, L. E., Huisman, C., Span, S. W., Rodriguez, J. A., Kruyt, F. A., and Giaccone, G. (2004) Cathepsin B mediates caspase-independent cell death induced by microtubule stabilizing agents in non-small cell lung cancer cells Cancer Res. 64, 27-30 (Pubitemid 38114077)
    • (2004) Cancer Research , vol.64 , Issue.1 , pp. 27-30
    • Broker, L.E.1    Huisman, C.2    Span, S.W.3    Rodriguez, J.A.4    Kruyt, F.A.E.5    Giaccone, G.6
  • 174
    • 75749122303 scopus 로고    scopus 로고
    • Methods in mammalian autophagy research
    • Mizushima, N., Yoshimori, T., and Levine, B. (2010) Methods in mammalian autophagy research Cell 140, 313-326
    • (2010) Cell , vol.140 , pp. 313-326
    • Mizushima, N.1    Yoshimori, T.2    Levine, B.3
  • 176
    • 43949123587 scopus 로고    scopus 로고
    • Fenretinide induces autophagic cell death in caspase-defective breast cancer cells
    • Fazi, B., Bursch, W., Fimia, G. M., Nardacci, R., Piacentini, M., Di San, F., and Piredda, L. (2008) Fenretinide induces autophagic cell death in caspase-defective breast cancer cells Autophagy 4, 435-441 (Pubitemid 351705140)
    • (2008) Autophagy , vol.4 , Issue.4 , pp. 435-441
    • Fazi, B.1    Bursch, W.2    Fimia, G.M.3    Nardacci, R.4    Piacentini, M.5    Di Sano, F.6    Piredda, L.7
  • 178
    • 56749170677 scopus 로고    scopus 로고
    • Autophagic cell death: The story of a misnomer
    • Kroemer, G. and Levine, B. (2008) Autophagic cell death: the story of a misnomer Nat. Rev. Mol. Cell Biol. 9, 1004-1010
    • (2008) Nat. Rev. Mol. Cell Biol. , vol.9 , pp. 1004-1010
    • Kroemer, G.1    Levine, B.2
  • 179
    • 84856748733 scopus 로고    scopus 로고
    • Cell death by autophagy: Facts and apparent artefacts
    • Denton, D., Nicolson, S., and Kumar, S. (2012) Cell death by autophagy: facts and apparent artefacts Cell Death Differ. 19, 87-95
    • (2012) Cell Death Differ. , vol.19 , pp. 87-95
    • Denton, D.1    Nicolson, S.2    Kumar, S.3
  • 180
    • 34249796389 scopus 로고    scopus 로고
    • HMGB1: A signal of necrosis
    • DOI 10.1080/08916930701356978, PII 778899431
    • Raucci, A., Palumbo, R., and Bianchi, M. E. (2007) HMGB1: a signal of necrosis Autoimmunity 40, 285-289 (Pubitemid 46845522)
    • (2007) Autoimmunity , vol.40 , Issue.4 , pp. 285-289
    • Raucci, A.1    Palumbo, R.2    Bianchi, M.E.3
  • 181
    • 77950366886 scopus 로고    scopus 로고
    • Decoding cell death signals in inflammation and immunity
    • Zitvogel, L., Kepp, O., and Kroemer, G. (2010) Decoding cell death signals in inflammation and immunity Cell 140, 798-804
    • (2010) Cell , vol.140 , pp. 798-804
    • Zitvogel, L.1    Kepp, O.2    Kroemer, G.3
  • 182
    • 67650493786 scopus 로고    scopus 로고
    • Novel HMGB1-inhibiting therapeutic agents for experimental sepsis
    • Wang, H., Ward, M. F., and Sama, A. E. (2009) Novel HMGB1-inhibiting therapeutic agents for experimental sepsis Stroke 32, 348-357
    • (2009) Stroke , vol.32 , pp. 348-357
    • Wang, H.1    Ward, M.F.2    Sama, A.E.3
  • 183
    • 79955473647 scopus 로고    scopus 로고
    • Anti-high mobility group box-1 monoclonal antibody protects the blood-brain barrier from ischemia-induced disruption in rats
    • Zhang, J., Takahashi, H. K., Liu, K., Wake, H., Liu, R., Maruo, T., Date, I., Yoshino, T., Ohtsuka, A., Mori, S., and Nishibori, M. (2011) Anti-high mobility group box-1 monoclonal antibody protects the blood-brain barrier from ischemia-induced disruption in rats Stroke 42, 1420-1428
    • (2011) Stroke , vol.42 , pp. 1420-1428
    • Zhang, J.1    Takahashi, H.K.2    Liu, K.3    Wake, H.4    Liu, R.5    Maruo, T.6    Date, I.7    Yoshino, T.8    Ohtsuka, A.9    Mori, S.10    Nishibori, M.11
  • 186
    • 26844468253 scopus 로고    scopus 로고
    • Cell-surface calreticulin initiates clearance of viable or apoptotic cells through trans-activation of LRP on the phagocyte
    • DOI 10.1016/j.cell.2005.08.032, PII S009286740500869X
    • Gardai, S. J., McPhillips, K. A., Frasch, S. C., Janssen, W. J., Starefeldt., A., Murphy-Ullrich, J. E., Bratton, D. L., Oldenborg, P. A., Michalak, M., and Henson, P. M. (2005) Cell-surface calreticulin initiates clearance of viable or apoptotic cells through trans-activation of LRP on the phagocyte Cell 123, 321-334 (Pubitemid 41457220)
    • (2005) Cell , vol.123 , Issue.2 , pp. 321-334
    • Gardai, S.J.1    McPhillips, K.A.2    Frasch, S.C.3    Janssen, W.J.4    Starefeldt, A.5    Murphy-Ullrich, J.E.6    Bratton, D.L.7    Oldenborg, P.-A.8    Michalak, M.9    Henson, P.M.10
  • 187
    • 77953701142 scopus 로고    scopus 로고
    • Immunogenic tumor cell death for optimal anticancer therapy: The calreticulin exposure pathway
    • Zitvogel, L., Kepp, O., Senovilla, L., Menger, L., Chaput, N., and Kroemer, G. (2010) Immunogenic tumor cell death for optimal anticancer therapy: the calreticulin exposure pathway Clin. Cancer Res. 16, 3100-3104
    • (2010) Clin. Cancer Res. , vol.16 , pp. 3100-3104
    • Zitvogel, L.1    Kepp, O.2    Senovilla, L.3    Menger, L.4    Chaput, N.5    Kroemer, G.6
  • 188
    • 84867569117 scopus 로고    scopus 로고
    • Targeting of calreticulin exposure for optical imaging of etoposide-induced immunogenic tumor cell death
    • Jung, K. H., Palik, J. Y., Park, J., Quach, C., Lee, E. J., Choe, Y. S., and Lee, K.-H. (2011) Targeting of calreticulin exposure for optical imaging of etoposide-induced immunogenic tumor cell death Mol. Cancer Ther. 10 (Supp.1) B111
    • (2011) Mol. Cancer Ther. , vol.10 , Issue.SUPPL. 1 , pp. 111
    • Jung, K.H.1    Palik, J.Y.2    Park, J.3    Quach, C.4    Lee, E.J.5    Choe, Y.S.6    Lee, K.-H.7
  • 190
    • 2342570379 scopus 로고    scopus 로고
    • Hallmarks of senescence in carcinogenesis and cancer therapy
    • DOI 10.1038/sj.onc.1207518
    • Shay, J. W. and Roninson, I. B. (2004) Hallmarks of senescence in carcinogenesis and cancer therapy Oncogene 23, 2919-2933 (Pubitemid 38638853)
    • (2004) Oncogene , vol.23 , Issue.16 , pp. 2919-2933
    • Shay, J.W.1    Roninson, I.B.2
  • 192
    • 72949096792 scopus 로고    scopus 로고
    • Senescence in tumours: Evidence from mice and humans
    • Collado, M. and Serrano, M. (2010) Senescence in tumours: evidence from mice and humans Nat. Rev. Cancer 10, 51-57
    • (2010) Nat. Rev. Cancer , vol.10 , pp. 51-57
    • Collado, M.1    Serrano, M.2
  • 193
    • 74949127989 scopus 로고    scopus 로고
    • Protocols to detect senescence-associated β-galactosidase (SA-βgal) activity, a biomarker of senescent cells in culture and in vivo
    • Debacq-Chainiaux, F., Erusalimsky, J. D., Campisi, J., and Toussaint, O. (2009) Protocols to detect senescence-associated β-galactosidase (SA-βgal) activity, a biomarker of senescent cells in culture and in vivo Nat. Prot. 4, 1798-1806
    • (2009) Nat. Prot. , vol.4 , pp. 1798-1806
    • Debacq-Chainiaux, F.1    Erusalimsky, J.D.2    Campisi, J.3    Toussaint, O.4
  • 194
    • 33846937033 scopus 로고    scopus 로고
    • Senescence and tumour clearance is triggered by p53 restoration in murine liver carcinomas
    • DOI 10.1038/nature05529, PII NATURE05529
    • Xue, W., Zender, L., Miething, C., Dickins, R. A., Hernando, E., Krizhanovsky, V., Cordon-Cardo, C., and Lowe, S. W. (2007) Senescence and tumour clearance is triggered by p53 restoration in murine liver carcinomas Nature 445, 656-660 (Pubitemid 46232886)
    • (2007) Nature , vol.445 , Issue.7128 , pp. 656-660
    • Xue, W.1    Zender, L.2    Miething, C.3    Dickins, R.A.4    Hernando, E.5    Krizhanovsky, V.6    Cordon-Cardo, C.7    Lowe, S.W.8
  • 195
    • 1642328231 scopus 로고    scopus 로고
    • In Vivo Imaging of β-Galactosidase Activity Using Far Red Fluorescent Switch
    • DOI 10.1158/0008-5472.CAN-03-3226
    • Tung, C. H., Zeng, Q., Shah, K., Kim, D. E., Schellingerhout, D., and Weissleder, R. (2004) In vivo imaging of β-galactosidase activity using far red fluorescent switch Cancer Res. 64, 1579-1583 (Pubitemid 38428674)
    • (2004) Cancer Research , vol.64 , Issue.5 , pp. 1579-1583
    • Tung, C.-H.1    Zeng, Q.2    Shah, K.3    Kim, D.-E.4    Schellingerhout, D.5    Weissleder, R.6
  • 196
    • 77957778864 scopus 로고    scopus 로고
    • Imaging β-galactosidase activity in human tumor xenografts and transgenic mice using a chemiluminescent substrate
    • Liu, L. and Mason, R. P. (2010) Imaging β-galactosidase activity in human tumor xenografts and transgenic mice using a chemiluminescent substrate PLoS One 5, e12024
    • (2010) PLoS One , vol.5 , pp. 12024
    • Liu, L.1    Mason, R.P.2
  • 200
    • 80755180853 scopus 로고    scopus 로고
    • Beginnings of a good apoptotic meal: The find-me and eat-me signaling pathways
    • Ravichandran, K. S. (2011) Beginnings of a good apoptotic meal: the find-me and eat-me signaling pathways Immunity 35, 445-455
    • (2011) Immunity , vol.35 , pp. 445-455
    • Ravichandran, K.S.1
  • 203
    • 20144374032 scopus 로고    scopus 로고
    • A monoclonal antibody that binds anionic phospholipids on tumor blood vessels enhances the antitumor effect of docetaxel on human breast tumors in mice
    • DOI 10.1158/0008-5472.CAN-05-0031
    • Huang, X., Bennett, M., and Thorpe, P. E. (2005) A monoclonal antibody that binds anionic phospholipids on tumor blood vessels enhances the antitumor effect of docetaxel on human breast tumors in mice Cancer Res. 65, 4408-4416 (Pubitemid 40775680)
    • (2005) Cancer Research , vol.65 , Issue.10 , pp. 4408-4416
    • Huang, X.1    Bennett, M.2    Thorpe, P.E.3
  • 204
    • 33646420098 scopus 로고    scopus 로고
    • Combination of a monoclonal anti-phosphatidylserine antibody with gemcitabine strongly inhibits the growth and metastasis of orthotopic pancreatic tumors in mice
    • Beck, A. W., Luster, T. A., Miller, A. F., Holloway, S. E., Conner, C. R., Barnett, C. C., Thorpe, P. E., Fleming, J. B., and Brekken, R. A. (2006) Combination of a monoclonal anti-phosphatidylserine antibody with gemcitabine strongly inhibits the growth and metastasis of orthotopic pancreatic tumors in mice Int. J. Cancer 118, 2639-2643
    • (2006) Int. J. Cancer , vol.118 , pp. 2639-2643
    • Beck, A.W.1    Luster, T.A.2    Miller, A.F.3    Holloway, S.E.4    Conner, C.R.5    Barnett, C.C.6    Thorpe, P.E.7    Fleming, J.B.8    Brekken, R.A.9
  • 205
    • 72549108621 scopus 로고    scopus 로고
    • Antiphosphatidylserine antibody combined with irradiation damages tumor blood vessels and induces tumor immunity in a rat model of gliobastoma
    • He, J., Yin, Y., Luster, T. A., Watkins, L., and Thorpe, P. E. (2009) Antiphosphatidylserine antibody combined with irradiation damages tumor blood vessels and induces tumor immunity in a rat model of gliobastoma Clin. Cancer Res. 15, 6871-6880
    • (2009) Clin. Cancer Res. , vol.15 , pp. 6871-6880
    • He, J.1    Yin, Y.2    Luster, T.A.3    Watkins, L.4    Thorpe, P.E.5
  • 206
    • 34447121852 scopus 로고    scopus 로고
    • MFG-E8-mediated uptake of apoptotic cells by APCs links the pro- and antiinflammatory activities of GM-CSF
    • DOI 10.1172/JCI30966
    • Jinushi, M., Nakazaki, Y., Dougan, M., Carrasco, D. R., Mihm, M., and Dranoff, G. (2007) MFG-E8-mediated uptake of apoptotic cells by APCs links the pro- and antiinflammatory activities of GM-CSF J. Clin. Invest. 117, 1902-1913 (Pubitemid 47036324)
    • (2007) Journal of Clinical Investigation , vol.117 , Issue.7 , pp. 1902-1913
    • Jinushi, M.1    Nakazaki, Y.2    Dougan, M.3    Carrasco, D.R.4    Mihm, M.5    Dranoff, G.6
  • 212
    • 79953719964 scopus 로고    scopus 로고
    • Role of Bcl-2 family proteins and caspases in the regulation of apoptosis
    • Ola, M. S., Nawaz, M., and Ahsan, H. (2011) Role of Bcl-2 family proteins and caspases in the regulation of apoptosis Mol. Cell. Biochem. 351, 41-58
    • (2011) Mol. Cell. Biochem. , vol.351 , pp. 41-58
    • Ola, M.S.1    Nawaz, M.2    Ahsan, H.3
  • 213
    • 22744437978 scopus 로고    scopus 로고
    • Apoptosis-based therapies and drug targets
    • DOI 10.1038/sj.cdd.4401556
    • Fischer, U. and Schulze-Osthoff, K. (2005) Apoptosis-based therapies and drug targets Cell Death Differ. 12, 942-961 (Pubitemid 41030608)
    • (2005) Cell Death and Differentiation , vol.12 , Issue.SUPPL. 1 , pp. 942-961
    • Fischer, U.1    Schulze-Osthoff, K.2
  • 215
    • 4344616982 scopus 로고    scopus 로고
    • Targeting apoptosis via chemical design: Inhibition of bid-induced cell death by small organic molecules
    • DOI 10.1016/j.chembiol.2004.05.022, PII S1074552104001917
    • Becattini, B., Sareth, S., Zhai, D., Crowell, K. J., Leone, M., Reed, J. C., and Pellecchia, M. (2004) Targeting apoptosis via chemical design: inhibition of bid-induced cell death by small organic molecules Chem. Biol. 11, 1107-1117 (Pubitemid 39138763)
    • (2004) Chemistry and Biology , vol.11 , Issue.8 , pp. 1107-1117
    • Becattini, B.1    Sareth, S.2    Zhai, D.3    Crowell, K.J.4    Leone, M.5    Reed, J.C.6    Pellecchia, M.7
  • 217
    • 0036829818 scopus 로고    scopus 로고
    • L is protective after middle cerebral artery occlusion in mice
    • DOI 10.1002/ana.10356
    • Kilic, E., Dietz, G. P. H., Hermann, D. M., and Bähr, M. (2002) Intravenous TAT-Bcl-xL is protective after middle cerebral artery occlusion in mice Ann. Neurol. 52, 617-622 (Pubitemid 35246865)
    • (2002) Annals of Neurology , vol.52 , Issue.5 , pp. 617-622
    • Kilic, E.1    Dietz, G.P.H.2    Hermann, D.M.3    Bahr, M.4
  • 219
    • 50249132439 scopus 로고    scopus 로고
    • Necrostatin-1 reduced histopathology and improves functional outcome after controlled cortical impact in mice
    • You, Z., Savitz, S. I., Yang, J., Degterev, A., Yuan, J., Cuny, G. D., Moskowitz, and Whalen, M. J. (2008) Necrostatin-1 reduced histopathology and improves functional outcome after controlled cortical impact in mice J. Cereb. Blood Flow Metab. 28, 1564-1573
    • (2008) J. Cereb. Blood Flow Metab. , vol.28 , pp. 1564-1573
    • You, Z.1    Savitz, S.I.2    Yang, J.3    Degterev, A.4    Yuan, J.5    Cuny, G.D.6    Moskowitz7    Whalen, M.J.8
  • 221
    • 79954525274 scopus 로고    scopus 로고
    • Necrostatin-1 ameliorates symptoms in R6/2 transgenic mouse model of Huntington's disease
    • Zhu, S., Zhang, Y., Bai, G., and Li, H. (2011) Necrostatin-1 ameliorates symptoms in R6/2 transgenic mouse model of Huntington's disease Cell Death Dis. 2, e115
    • (2011) Cell Death Dis. , vol.2 , pp. 115
    • Zhu, S.1    Zhang, Y.2    Bai, G.3    Li, H.4
  • 222
    • 66149156964 scopus 로고    scopus 로고
    • Assessing tumor response to therapy
    • Weber, W. A. (2009) Assessing tumor response to therapy J. Nucl. Med. 50, 1S-10S
    • (2009) J. Nucl. Med. , vol.50
    • Weber, W.A.1
  • 223
    • 66149139452 scopus 로고    scopus 로고
    • From RECIST to PERCIST: Evolving considerations for PET response criteria in solid tumors
    • Wahl, R. L., Jacene, H., Kasamon, Y., and Lodge, M. A. (2009) From RECIST to PERCIST: evolving considerations for PET response criteria in solid tumors J. Nucl. Med. 50, 122S-150S
    • (2009) J. Nucl. Med. , vol.50
    • Wahl, R.L.1    Jacene, H.2    Kasamon, Y.3    Lodge, M.A.4
  • 224
    • 73449112258 scopus 로고    scopus 로고
    • Apoptosis imaging: Anti-cancer agents in medicinal chemistry
    • Blankenberg, F. G. (2009) Apoptosis imaging: anti-cancer agents in medicinal chemistry Anti-Cancer Agent. Med. Chem. 9, 944-951
    • (2009) Anti-Cancer Agent. Med. Chem. , vol.9 , pp. 944-951
    • Blankenberg, F.G.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.