In situ dose amplification by apoptosis-targeted drug delivery

Journal of Controlled Release

Volumn 154, Issue 3, 2011, Pages 214-217

  Wang, Kai ^a,g   Na, Moon Hee ^a   Hoffman, Allan S ^b,c   Shim, Gayong ^d   Han, Su Eun ^d   Oh, Yu Kyoung ^e   Kwon, Ick Chan ^f   Kim, In San ^a,b   Lee, Byung Heon ^a,b  

^a Kyungpook National University School of Medicine   (South Korea)

^b Kyungpook National University   (South Korea)

^c University of Washington   (United States)

^d Korea University   (South Korea)

^e Seoul National University   (South Korea)

^f Korea Institute of Science and Technology   (South Korea)

^g HENAN PROVINCIAL PEOPLE'S HOSPITAL   (China)

Author keywords

Apoptosis; Drug delivery; Histone H1; In situ dose amplification; Theragnosis

Indexed keywords

APOPTOTIC; APOPTOTIC CELLS; DOXORUBICIN; FLUORESCENCE IMAGING; HISTONE H1; IN SITU DOSE AMPLIFICATION; IN-SITU; IN-VITRO; REAL TIME MONITORING; THERAGNOSIS; TREATMENT RESPONSE; TUMOR CELLS; TUMOR GROWTH; TUMOR VOLUMES;

AMPLIFICATION; CHEMOTHERAPY; DRUG DELIVERY; DRUG DOSAGE; FLUORESCENCE; LIPOSOMES; MAMMALS; PHOSPHOLIPIDS; TUMORS;

CELL DEATH;

APOPEP 1; DOXORUBICIN; HISTONE H1; LIPOSOME; PEPTIDE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; CONTROLLED STUDY; DRUG DELIVERY SYSTEM; DRUG EFFICACY; DRUG TARGETING; LUNG TUMOR; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; SYNTHESIS; TREATMENT OUTCOME; TUMOR XENOGRAFT;

ANIMALS; ANTIBIOTICS, ANTINEOPLASTIC; APOPTOSIS; DOXORUBICIN; DRUG DELIVERY SYSTEMS; HISTONES; LIPOSOMES; MICE; NEOPLASMS; PEPTIDES;

EID: 80052552063     PISSN: 01683659     EISSN: 18734995     Source Type: Journal    
DOI: 10.1016/j.jconrel.2011.06.043     Document Type: Article

References (24)

1. T. Deguchi, M. Tanemura, E. Miyoshi, H. Nagano, T. Machida, Y. Ohmura, S. Kobayashi, S. Marubashi, H. Eguchi, Y. Takeda, T. Ito, M. Mori, Y. Doki, and Y. Sawa Increased immunogenicity of tumor-associated antigen, mucin 1, engineered to express alpha-gal epitopes: a novel approach to immunotherapy in pancreatic cancer Cancer Res. 70 2010 5259 5269
2. X. Li, L. Ding, Y. Xu, Y. Wang, and Q. Ping Targeted delivery of doxorubicin using stealth liposomes modified with transferrin Int. J. Pharm. 373 2009 116 123
3. X. Zhao, H. Li, and R.J. Lee Targeted drug delivery via folate receptors Expert Opin. Drug Deliv. 5 2008 309 319 (Pubitemid 351454380)
4. V.A. Fadok, D.R. Voelker, P.A. Campbell, J.J. Cohen, D.L. Bratton, and P.M. Henson Exposure of phosphatidylserine on the surface of apoptotic lymphocytes triggers specific recognition and removal by macrophages J. Immunol. 148 1992 2207 2216
5. R.F. Zwaal, and A.J. Schroit Pathophysiologic implications of membrane phospholipid asymmetry in blood cells Blood 89 1997 1121 1132 (Pubitemid 27079974)
6. M. Radic, T. Marion, and M. Monestier Nucleosomes are exposed at the cell surface in apoptosis J. Immunol. 172 2004 6692 6700 (Pubitemid 38669105)
7. D. Wu, A. Ingram, J.H. Lahti, B. Mazza, J. Grenet, A. Kapoor, L. Liu, V.J. Kidd, and D. Tang Apoptotic release of histones from nucleosomes J. Biol. Chem. 277 2002 12,001 12,008
8. K. Wang, S. Purushotham, J.Y. Lee, M.H. Na, H. Park, S.J. Oh, R.W. Park, J.Y. Park, E. Lee, B.C. Cho, M.N. Song, M.C. Baek, W. Kwak, J. Yoo, A.S. Hoffman, Y.K. Oh, I.S. Kim, and B.H. Lee In vivo imaging of tumor apoptosis using histone H1-targeting peptide J. Control. Release 148 2010 283 291
9. X. He, M.H. Na, J.S. Kim, G.Y. Lee, J.Y. Park, A.S. Hoffman, J.O. Nam, S.E. Han, G.Y. Sim, Y.K. Oh, I.S. Kim, and B.H. Lee A novel peptide probe for imaging and targeted delivery of liposomal doxorubicin to lung tumor Mol. Pharm. 8 2011 430 438
10. F. Al-Ejeh, J.M. Darby, and M.P. Brown Chemotherapy synergizes with radioimmunotherapy targeting La autoantigen in tumors PLoS One 4 2009 e4630
11. G. von Maltzahn, J.H. Park, K.Y. Lin, N. Singh, C. Schwoppe, R. Mesters, W.E. Berdel, E. Ruoslahti, M.J. Sailor, and S.N. Bhatia Nanoparticles that communicate in vivo to amplify tumour targeting Nat. Mater. 10 2011 545 552
12. S.H. Jang, M.G. Wientjes, and J.L. Au Enhancement of paclitaxel delivery to solid tumors by apoptosis-inducing pretreatment: effect of treatment schedule J. Pharmacol. Exp. Ther. 296 2001 1035 1042 (Pubitemid 32187379)
13. D. Lu, M.G. Wientjes, Z. Lu, and J.L. Au Tumor priming enhances delivery and efficacy of nanomedicines J. Pharmacol. Exp. Ther. 322 2007 80 88 (Pubitemid 46956353)
14. H.J. Kuh, S.H. Jang, M.G. Wientjes, J.R. Weaver, and J.L. Au Determinants of paclitaxel penetration and accumulation in human solid tumor J. Pharmacol. Exp. Ther. 290 1999 871 880 (Pubitemid 29344588)
15. R. Cairns, I. Papandreou, and N. Denko Overcoming physiologic barriers to cancer treatment by molecularly targeting the tumor microenvironment Mol. Cancer Res. 4 2006 61 70
16. A.I. Minchinton, and I.F. Tannock Drug penetration in solid tumours Nat. Rev. Cancer 6 2006 583 592 (Pubitemid 44140857)
17. T.M. Allen Ligand-targeted therapeutics in anticancer therapy Nat. Rev. Cancer 2 2002 750 763 (Pubitemid 37328910)
18. K. Kim, J.H. Kim, H. Park, Y.S. Kim, K. Park, H. Nam, S. Lee, J.H. Park, R.W. Park, I.S. Kim, K. Choi, S.Y. Kim, and I.C. Kwon Tumor-homing multifunctional nanoparticles for cancer theragnosis: simultaneous diagnosis, drug delivery, and therapeutic monitoring J. Control. Release 146 2010 219 227
19. S. Langereis, J. Keupp, J.L. van Velthoven, I.H. de Roos, D. Burdinski, J.A. Pikkemaat, and H. Grull A temperature-sensitive liposomal 1H CEST and 19F contrast agent for MR image-guided drug delivery J. Am. Chem. Soc. 131 2009 1380 1381
20. C. Fang, and M. Zhang Nanoparticle-based theragnostics: integrating diagnostic and therapeutic potentials in nanomedicine J. Control. Release 146 2010 2 5
21. Z. Medarova, L. Rashkovetsky, P. Pantazopoulos, and A. Moore Multiparametric monitoring of tumor response to chemotherapy by noninvasive imaging Cancer Res. 69 2009 1182 1189
22. A.R. Padhani, and L. Ollivier The RECIST (Response Evaluation Criteria in Solid Tumors) criteria: implications for diagnostic radiologists Br. J. Radiol. 74 2001 983 986 (Pubitemid 33121128)
23. R. Weissleder, and M.J. Pittet Imaging in the era of molecular oncology Nature 452 2008 580 589 (Pubitemid 351483372)
24. F.G. Blankenberg Apoptosis imaging: anti-cancer agents in medicinal chemistry Anticancer Agents Med. Chem. 9 2009 944 951