메뉴 건너뛰기




Volumn 15, Issue 8, 2009, Pages 967-973

Noninvasive optical imaging of apoptosis by caspase-targeted activity-based probes

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE; CATHEPSIN; DEXAMETHASONE; FLUORESCENT DYE; MONOCLONAL ANTIBODY;

EID: 68349148319     PISSN: 10788956     EISSN: 1546170X     Source Type: Journal    
DOI: 10.1038/nm.1938     Document Type: Article
Times cited : (250)

References (35)
  • 1
    • 4344651705 scopus 로고    scopus 로고
    • Visualization of antitumor treatment by means of fluorescence molecular tomography with an annexin V-Cy5.5 conjugate
    • Ntziachristos, V. et al. Visualization of antitumor treatment by means of fluorescence molecular tomography with an annexin V-Cy5.5 conjugate. Proc. Natl. Acad. Sci. USA 101, 12294-12299 (2004).
    • (2004) Proc. Natl. Acad. Sci. USA , vol.101 , pp. 12294-12299
    • Ntziachristos, V.1
  • 3
    • 0013162104 scopus 로고    scopus 로고
    • Optical imaging of apoptosis as a biomarker of tumor response to chemotherapy
    • Schellenberger, E.A. et al. Optical imaging of apoptosis as a biomarker of tumor response to chemotherapy. Neoplasia 5, 187-192 (2003).
    • (2003) Neoplasia , vol.5 , pp. 187-192
    • Schellenberger, E.A.1
  • 4
    • 34250667135 scopus 로고    scopus 로고
    • Radiolabeling of HYNIC-annexin V with technetium-99m for in vivo imaging of apoptosis
    • Blankenberg, F.G., Vanderheyden, J.L., Strauss, H.W. & Tait, J.F. Radiolabeling of HYNIC-annexin V with technetium-99m for in vivo imaging of apoptosis. Nat. Protoc. 1, 108-110 (2006).
    • (2006) Nat. Protoc , vol.1 , pp. 108-110
    • Blankenberg, F.G.1    Vanderheyden, J.L.2    Strauss, H.W.3    Tait, J.F.4
  • 5
    • 0036717347 scopus 로고    scopus 로고
    • Increased uptake of the apoptosis-imaging agent (99m)Tc recombinant human Annexin V in human tumors after one course of chemotherapy as a predictor of tumor response and patient prognosis
    • Belhocine, T. et al. Increased uptake of the apoptosis-imaging agent (99m)Tc recombinant human Annexin V in human tumors after one course of chemotherapy as a predictor of tumor response and patient prognosis. Clin. Cancer Res. 8, 2766-2774 (2002).
    • (2002) Clin. Cancer Res , vol.8 , pp. 2766-2774
    • Belhocine, T.1
  • 6
    • 34447508702 scopus 로고    scopus 로고
    • Sequential 99mTc-hydrazinonicotinamide-annexin V imaging for predicting response to chemotherapy
    • Rottey, S., Siegers, G., Van Belle, S., Goethals, I. & Van de Wiele, C. Sequential 99mTc-hydrazinonicotinamide-annexin V imaging for predicting response to chemotherapy. J. Nucl. Med. 47, 1813-1818 (2006).
    • (2006) J. Nucl. Med , vol.47 , pp. 1813-1818
    • Rottey, S.1    Siegers, G.2    Van Belle, S.3    Goethals, I.4    Van de Wiele, C.5
  • 7
    • 5144221644 scopus 로고    scopus 로고
    • 99mTc-HYNIC Annexin-V imaging of primary head and neck carcinoma
    • Vermeersch, H. et al. 99mTc-HYNIC Annexin-V imaging of primary head and neck carcinoma. Nucl. Med. Commun. 25, 259-263 (2004).
    • (2004) Nucl. Med. Commun , vol.25 , pp. 259-263
    • Vermeersch, H.1
  • 8
    • 0034661803 scopus 로고    scopus 로고
    • Visualisation of cell death in vivo in patients with acute myocardial infarction
    • Hofstra, L. et al. Visualisation of cell death in vivo in patients with acute myocardial infarction. Lancet 356, 209-212 (2000).
    • (2000) Lancet , vol.356 , pp. 209-212
    • Hofstra, L.1
  • 9
    • 33845364699 scopus 로고    scopus 로고
    • Molecular imaging of cell death in vivo by a novel small molecule probe
    • Aloya, R. et al. Molecular imaging of cell death in vivo by a novel small molecule probe. Apoptosis 11, 2089-2101 (2006).
    • (2006) Apoptosis , vol.11 , pp. 2089-2101
    • Aloya, R.1
  • 10
    • 67649109027 scopus 로고    scopus 로고
    • From the Gla domain to a novel small-molecule detector of apoptosis
    • Cohen, A. et al. From the Gla domain to a novel small-molecule detector of apoptosis. Cell Res. 19, 625-637 (2009).
    • (2009) Cell Res , vol.19 , pp. 625-637
    • Cohen, A.1
  • 11
    • 0037168582 scopus 로고    scopus 로고
    • Noninvasive real-time imaging of apoptosis
    • Laxman, B. et al. Noninvasive real-time imaging of apoptosis. Proc. Natl. Acad. Sci. USA 199, 16551-16555 (2002).
    • (2002) Proc. Natl. Acad. Sci. USA , vol.199 , pp. 16551-16555
    • Laxman, B.1
  • 12
    • 23944469298 scopus 로고    scopus 로고
    • Synthesis and characterization of a small, membrane-permeant, caspase-activatable far-red fluorescent peptide for imaging apoptosis
    • Bullok, K. & Piwnica-Worms, D. Synthesis and characterization of a small, membrane-permeant, caspase-activatable far-red fluorescent peptide for imaging apoptosis. J. Med. Chem. 48, 5404-5407 (2005).
    • (2005) J. Med. Chem , vol.48 , pp. 5404-5407
    • Bullok, K.1    Piwnica-Worms, D.2
  • 13
    • 23044458593 scopus 로고    scopus 로고
    • 1311-labeled peptides as caspase substrates for apoptosis imaging
    • Bauer, C., Bauder-Wuest, U., Mier, W., Haberkorn, U. & Eisenhut, M. 1311-labeled peptides as caspase substrates for apoptosis imaging. J. Nucl. Med. 46, 1066-1074 (2005).
    • (2005) J. Nucl. Med , vol.46 , pp. 1066-1074
    • Bauer, C.1    Bauder-Wuest, U.2    Mier, W.3    Haberkorn, U.4    Eisenhut, M.5
  • 14
    • 0030849093 scopus 로고    scopus 로고
    • A combinatorial approach defines specificities of members of the caspase family and granzyme B. Functional relationships established for key mediators of apoptosis
    • Thornberry, N.A. et al. A combinatorial approach defines specificities of members of the caspase family and granzyme B. Functional relationships established for key mediators of apoptosis. J. Biol. Chem. 272, 17907-17911 (1997).
    • (1997) J. Biol. Chem , vol.272 , pp. 17907-17911
    • Thornberry, N.A.1
  • 15
    • 29444460784 scopus 로고    scopus 로고
    • Activity-based probes that target diverse cysteine protease families
    • Kato, D. et al. Activity-based probes that target diverse cysteine protease families. Nat. Chem. Biol. 1, 33-38 (2005).
    • (2005) Nat. Chem. Biol , vol.1 , pp. 33-38
    • Kato, D.1
  • 16
    • 33846188177 scopus 로고    scopus 로고
    • Design of cell-permeable, fluorescent activity-based probes for the lysosomal cysteine protease asparaginyl endopeptidase (AEP)/legumain
    • Sexton, K.B., Witte, M.D., Blum, G. & Bogyo, M. Design of cell-permeable, fluorescent activity-based probes for the lysosomal cysteine protease asparaginyl endopeptidase (AEP)/legumain. Bioorg. Med. Chem. Lett. 17, 649-653 (2007).
    • (2007) Bioorg. Med. Chem. Lett , vol.17 , pp. 649-653
    • Sexton, K.B.1    Witte, M.D.2    Blum, G.3    Bogyo, M.4
  • 17
    • 33747355468 scopus 로고    scopus 로고
    • Synthesis, radiolabeling and in vivo evaluation of an 18F-labeled isatin analog for imaging caspase-3 activation in apoptosis
    • Zhou, D. et al. Synthesis, radiolabeling and in vivo evaluation of an 18F-labeled isatin analog for imaging caspase-3 activation in apoptosis. Bioorg. Med. Chem. Lett. 16, 5041-5046 (2006).
    • (2006) Bioorg. Med. Chem. Lett , vol.16 , pp. 5041-5046
    • Zhou, D.1
  • 18
    • 0034714009 scopus 로고    scopus 로고
    • Activation of caspases measured in situ by binding of fluorochrome-labeled inhibitors of caspases (FLICA): Correlation with DNA fragmentation
    • Bedner, E., Smolewski, P., Amstad, P. & Darzynkiewicz, Z. Activation of caspases measured in situ by binding of fluorochrome-labeled inhibitors of caspases (FLICA): correlation with DNA fragmentation. Exp. Cell Res. 259, 308-313 (2000).
    • (2000) Exp. Cell Res , vol.259 , pp. 308-313
    • Bedner, E.1    Smolewski, P.2    Amstad, P.3    Darzynkiewicz, Z.4
  • 19
    • 0035340652 scopus 로고    scopus 로고
    • Detection of caspases activation by fluorochrome-labeled inhibitors: Multiparameter analysis by laser scanning cytometry
    • Smolewski, P. et al. Detection of caspases activation by fluorochrome-labeled inhibitors: multiparameter analysis by laser scanning cytometry. Cytometry 44, 73-82 (2001).
    • (2001) Cytometry , vol.44 , pp. 73-82
    • Smolewski, P.1
  • 20
    • 3142616523 scopus 로고    scopus 로고
    • A caspase active site probe reveals high fractional inhibition needed to block DNA fragmentation
    • Méthot, N. et al. A caspase active site probe reveals high fractional inhibition needed to block DNA fragmentation. J. Biol. Chem. 279, 27905-27914 (2004).
    • (2004) J. Biol. Chem , vol.279 , pp. 27905-27914
    • Méthot, N.1
  • 21
    • 0242526431 scopus 로고    scopus 로고
    • Interactions of fluorochrome-labeled caspase inhibitors with apoptotic cells: A caution in data interpretation
    • Pozarowski, P. et al. Interactions of fluorochrome-labeled caspase inhibitors with apoptotic cells: a caution in data interpretation. Cytometry A 55, 50-60 (2003).
    • (2003) Cytometry A , vol.55 , pp. 50-60
    • Pozarowski, P.1
  • 22
    • 12444315984 scopus 로고    scopus 로고
    • Inhibition of papain-like cysteine proteases and legumain by caspase-specific inhibitors: When reaction mechanism is more important than specificity
    • Rozman-Pungerčar, J. et al. Inhibition of papain-like cysteine proteases and legumain by caspase-specific inhibitors: when reaction mechanism is more important than specificity. Cell Death Differ. 10, 881-888 (2003).
    • (2003) Cell Death Differ , vol.10 , pp. 881-888
    • Rozman-Pungerčar, J.1
  • 23
    • 33746972404 scopus 로고    scopus 로고
    • Identification of early intermediates of caspase activation using selective inhibitors and activity-based probes
    • Berger, A.B. et al. Identification of early intermediates of caspase activation using selective inhibitors and activity-based probes. Mol. Cell 23, 509-521 (2006).
    • (2006) Mol. Cell , vol.23 , pp. 509-521
    • Berger, A.B.1
  • 24
    • 0033180211 scopus 로고    scopus 로고
    • Reversible tumorigenesis by MYC in hematopoietic lineages
    • Felsher, D.W. & Bishop, J.M. Reversible tumorigenesis by MYC in hematopoietic lineages. Mol. Cell 4, 199-207 (1999).
    • (1999) Mol. Cell , vol.4 , pp. 199-207
    • Felsher, D.W.1    Bishop, J.M.2
  • 25
    • 17644386231 scopus 로고    scopus 로고
    • Cellular uptake of unconjugated TAT peptide involves clathrin-dependent endocytosis and heparan sulfate receptors
    • Richard, J.P. et al. Cellular uptake of unconjugated TAT peptide involves clathrin-dependent endocytosis and heparan sulfate receptors. J. Biol. Chem. 280, 15300-15306 (2005).
    • (2005) J. Biol. Chem , vol.280 , pp. 15300-15306
    • Richard, J.P.1
  • 26
    • 0027015928 scopus 로고
    • Glucocorticoid-induced apoptosis in the thymus
    • Cohen, J.J. Glucocorticoid-induced apoptosis in the thymus. Semin. Immunol. 4, 363-369 (1992).
    • (1992) Semin. Immunol , vol.4 , pp. 363-369
    • Cohen, J.J.1
  • 27
    • 0036162988 scopus 로고    scopus 로고
    • Macrophages are involved in DNA degradation of apoptotic cells in murine thymus after administration of hydrocortisone
    • Odaka, C. & Mizuochi, T. Macrophages are involved in DNA degradation of apoptotic cells in murine thymus after administration of hydrocortisone. Cell Death Differ. 9, 104-112 (2002).
    • (2002) Cell Death Differ , vol.9 , pp. 104-112
    • Odaka, C.1    Mizuochi, T.2
  • 28
    • 0037103223 scopus 로고    scopus 로고
    • Thymocyte apoptosis induced by T cell activation is mediated by glucocorticoids in vivo
    • Brewer, J.A., Kanagawa, O., Sleckman, B.P. & Muglia, L.J. Thymocyte apoptosis induced by T cell activation is mediated by glucocorticoids in vivo. J. Immunol. 169, 1837-1843 (2002).
    • (2002) J. Immunol , vol.169 , pp. 1837-1843
    • Brewer, J.A.1    Kanagawa, O.2    Sleckman, B.P.3    Muglia, L.J.4
  • 29
    • 34547111256 scopus 로고    scopus 로고
    • 123l]annexin V and in situ oligonucleotide ligation
    • 123l]annexin V and in situ oligonucleotide ligation. J. Mol. Histol. 38, 313-319 (2007).
    • (2007) J. Mol. Histol , vol.38 , pp. 313-319
    • Zavitsanou, K.1
  • 30
    • 40949138762 scopus 로고    scopus 로고
    • Structural and functional analysis of the interaction between the agonistic monoclonal antibody Apomab and the proapoptotic receptor DR5
    • Adams, C. et al. Structural and functional analysis of the interaction between the agonistic monoclonal antibody Apomab and the proapoptotic receptor DR5. Cell Death Differ. 15, 751-761 (2008).
    • (2008) Cell Death Differ , vol.15 , pp. 751-761
    • Adams, C.1
  • 31
    • 44749085513 scopus 로고    scopus 로고
    • Targeting the extrinsic apoptosis pathway in cancer
    • Ashkenazi, A. Targeting the extrinsic apoptosis pathway in cancer. Cytokine Growth Factor Rev. 19, 325-331 (2008).
    • (2008) Cytokine Growth Factor Rev , vol.19 , pp. 325-331
    • Ashkenazi, A.1
  • 32
    • 0030904245 scopus 로고    scopus 로고
    • A truncated HIV-1 Tat protein basic domain rapidly translocates through the plasma membrane and accumulates in the cell nucleus
    • Vivès, E., Brodin, P. & Lebleu, B. A truncated HIV-1 Tat protein basic domain rapidly translocates through the plasma membrane and accumulates in the cell nucleus. J. Biol. Chem. 272, 16010-16017 (1997).
    • (1997) J. Biol. Chem , vol.272 , pp. 16010-16017
    • Vivès, E.1    Brodin, P.2    Lebleu, B.3
  • 33
    • 33947395719 scopus 로고    scopus 로고
    • Specificity of aza-peptide electrophile activity-based probes of caspases
    • Sexton, K.B. et al. Specificity of aza-peptide electrophile activity-based probes of caspases. Cell Death Differ. 14, 727-732 (2007).
    • (2007) Cell Death Differ , vol.14 , pp. 727-732
    • Sexton, K.B.1
  • 34
    • 0035891721 scopus 로고    scopus 로고
    • Parallel solution-phase synthesis of mechanism-based cysteine protease inhibitors
    • Lee, A. & Ellman, J.A. Parallel solution-phase synthesis of mechanism-based cysteine protease inhibitors. Org. Lett. 3, 3707-3709 (2001).
    • (2001) Org. Lett , vol.3 , pp. 3707-3709
    • Lee, A.1    Ellman, J.A.2
  • 35
    • 34548666006 scopus 로고    scopus 로고
    • Noninvasive optical imaging of cysteine protease activity using fluorescently quenched activity-based probes
    • Blum, G., von Degenfeld, G., Merchant, M.J., Blau, H.M. & Bogyo, M. Noninvasive optical imaging of cysteine protease activity using fluorescently quenched activity-based probes. Nat. Chem. Biol. 3, 668-677 (2007).
    • (2007) Nat. Chem. Biol , vol.3 , pp. 668-677
    • Blum, G.1    von Degenfeld, G.2    Merchant, M.J.3    Blau, H.M.4    Bogyo, M.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.