-
1
-
-
4344651705
-
Visualization of antitumor treatment by means of fluorescence molecular tomography with an annexin V-Cy5.5 conjugate
-
Ntziachristos, V. et al. Visualization of antitumor treatment by means of fluorescence molecular tomography with an annexin V-Cy5.5 conjugate. Proc. Natl. Acad. Sci. USA 101, 12294-12299 (2004).
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, pp. 12294-12299
-
-
Ntziachristos, V.1
-
2
-
-
0037447317
-
Near-infrared fluorescent imaging of tumor apoptosis
-
Petrovsky, A., Schellenberger, E., Josephson, L., Weissleder, R. & Bogdanov, A. Jr. Near-infrared fluorescent imaging of tumor apoptosis. Cancer Res. 63, 1936-1942 (2003).
-
(2003)
Cancer Res
, vol.63
, pp. 1936-1942
-
-
Petrovsky, A.1
Schellenberger, E.2
Josephson, L.3
Weissleder, R.4
Bogdanov Jr., A.5
-
3
-
-
0013162104
-
Optical imaging of apoptosis as a biomarker of tumor response to chemotherapy
-
Schellenberger, E.A. et al. Optical imaging of apoptosis as a biomarker of tumor response to chemotherapy. Neoplasia 5, 187-192 (2003).
-
(2003)
Neoplasia
, vol.5
, pp. 187-192
-
-
Schellenberger, E.A.1
-
4
-
-
34250667135
-
Radiolabeling of HYNIC-annexin V with technetium-99m for in vivo imaging of apoptosis
-
Blankenberg, F.G., Vanderheyden, J.L., Strauss, H.W. & Tait, J.F. Radiolabeling of HYNIC-annexin V with technetium-99m for in vivo imaging of apoptosis. Nat. Protoc. 1, 108-110 (2006).
-
(2006)
Nat. Protoc
, vol.1
, pp. 108-110
-
-
Blankenberg, F.G.1
Vanderheyden, J.L.2
Strauss, H.W.3
Tait, J.F.4
-
5
-
-
0036717347
-
Increased uptake of the apoptosis-imaging agent (99m)Tc recombinant human Annexin V in human tumors after one course of chemotherapy as a predictor of tumor response and patient prognosis
-
Belhocine, T. et al. Increased uptake of the apoptosis-imaging agent (99m)Tc recombinant human Annexin V in human tumors after one course of chemotherapy as a predictor of tumor response and patient prognosis. Clin. Cancer Res. 8, 2766-2774 (2002).
-
(2002)
Clin. Cancer Res
, vol.8
, pp. 2766-2774
-
-
Belhocine, T.1
-
6
-
-
34447508702
-
Sequential 99mTc-hydrazinonicotinamide-annexin V imaging for predicting response to chemotherapy
-
Rottey, S., Siegers, G., Van Belle, S., Goethals, I. & Van de Wiele, C. Sequential 99mTc-hydrazinonicotinamide-annexin V imaging for predicting response to chemotherapy. J. Nucl. Med. 47, 1813-1818 (2006).
-
(2006)
J. Nucl. Med
, vol.47
, pp. 1813-1818
-
-
Rottey, S.1
Siegers, G.2
Van Belle, S.3
Goethals, I.4
Van de Wiele, C.5
-
7
-
-
5144221644
-
99mTc-HYNIC Annexin-V imaging of primary head and neck carcinoma
-
Vermeersch, H. et al. 99mTc-HYNIC Annexin-V imaging of primary head and neck carcinoma. Nucl. Med. Commun. 25, 259-263 (2004).
-
(2004)
Nucl. Med. Commun
, vol.25
, pp. 259-263
-
-
Vermeersch, H.1
-
8
-
-
0034661803
-
Visualisation of cell death in vivo in patients with acute myocardial infarction
-
Hofstra, L. et al. Visualisation of cell death in vivo in patients with acute myocardial infarction. Lancet 356, 209-212 (2000).
-
(2000)
Lancet
, vol.356
, pp. 209-212
-
-
Hofstra, L.1
-
9
-
-
33845364699
-
Molecular imaging of cell death in vivo by a novel small molecule probe
-
Aloya, R. et al. Molecular imaging of cell death in vivo by a novel small molecule probe. Apoptosis 11, 2089-2101 (2006).
-
(2006)
Apoptosis
, vol.11
, pp. 2089-2101
-
-
Aloya, R.1
-
10
-
-
67649109027
-
From the Gla domain to a novel small-molecule detector of apoptosis
-
Cohen, A. et al. From the Gla domain to a novel small-molecule detector of apoptosis. Cell Res. 19, 625-637 (2009).
-
(2009)
Cell Res
, vol.19
, pp. 625-637
-
-
Cohen, A.1
-
11
-
-
0037168582
-
Noninvasive real-time imaging of apoptosis
-
Laxman, B. et al. Noninvasive real-time imaging of apoptosis. Proc. Natl. Acad. Sci. USA 199, 16551-16555 (2002).
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.199
, pp. 16551-16555
-
-
Laxman, B.1
-
12
-
-
23944469298
-
Synthesis and characterization of a small, membrane-permeant, caspase-activatable far-red fluorescent peptide for imaging apoptosis
-
Bullok, K. & Piwnica-Worms, D. Synthesis and characterization of a small, membrane-permeant, caspase-activatable far-red fluorescent peptide for imaging apoptosis. J. Med. Chem. 48, 5404-5407 (2005).
-
(2005)
J. Med. Chem
, vol.48
, pp. 5404-5407
-
-
Bullok, K.1
Piwnica-Worms, D.2
-
13
-
-
23044458593
-
1311-labeled peptides as caspase substrates for apoptosis imaging
-
Bauer, C., Bauder-Wuest, U., Mier, W., Haberkorn, U. & Eisenhut, M. 1311-labeled peptides as caspase substrates for apoptosis imaging. J. Nucl. Med. 46, 1066-1074 (2005).
-
(2005)
J. Nucl. Med
, vol.46
, pp. 1066-1074
-
-
Bauer, C.1
Bauder-Wuest, U.2
Mier, W.3
Haberkorn, U.4
Eisenhut, M.5
-
14
-
-
0030849093
-
A combinatorial approach defines specificities of members of the caspase family and granzyme B. Functional relationships established for key mediators of apoptosis
-
Thornberry, N.A. et al. A combinatorial approach defines specificities of members of the caspase family and granzyme B. Functional relationships established for key mediators of apoptosis. J. Biol. Chem. 272, 17907-17911 (1997).
-
(1997)
J. Biol. Chem
, vol.272
, pp. 17907-17911
-
-
Thornberry, N.A.1
-
15
-
-
29444460784
-
Activity-based probes that target diverse cysteine protease families
-
Kato, D. et al. Activity-based probes that target diverse cysteine protease families. Nat. Chem. Biol. 1, 33-38 (2005).
-
(2005)
Nat. Chem. Biol
, vol.1
, pp. 33-38
-
-
Kato, D.1
-
16
-
-
33846188177
-
Design of cell-permeable, fluorescent activity-based probes for the lysosomal cysteine protease asparaginyl endopeptidase (AEP)/legumain
-
Sexton, K.B., Witte, M.D., Blum, G. & Bogyo, M. Design of cell-permeable, fluorescent activity-based probes for the lysosomal cysteine protease asparaginyl endopeptidase (AEP)/legumain. Bioorg. Med. Chem. Lett. 17, 649-653 (2007).
-
(2007)
Bioorg. Med. Chem. Lett
, vol.17
, pp. 649-653
-
-
Sexton, K.B.1
Witte, M.D.2
Blum, G.3
Bogyo, M.4
-
17
-
-
33747355468
-
Synthesis, radiolabeling and in vivo evaluation of an 18F-labeled isatin analog for imaging caspase-3 activation in apoptosis
-
Zhou, D. et al. Synthesis, radiolabeling and in vivo evaluation of an 18F-labeled isatin analog for imaging caspase-3 activation in apoptosis. Bioorg. Med. Chem. Lett. 16, 5041-5046 (2006).
-
(2006)
Bioorg. Med. Chem. Lett
, vol.16
, pp. 5041-5046
-
-
Zhou, D.1
-
18
-
-
0034714009
-
Activation of caspases measured in situ by binding of fluorochrome-labeled inhibitors of caspases (FLICA): Correlation with DNA fragmentation
-
Bedner, E., Smolewski, P., Amstad, P. & Darzynkiewicz, Z. Activation of caspases measured in situ by binding of fluorochrome-labeled inhibitors of caspases (FLICA): correlation with DNA fragmentation. Exp. Cell Res. 259, 308-313 (2000).
-
(2000)
Exp. Cell Res
, vol.259
, pp. 308-313
-
-
Bedner, E.1
Smolewski, P.2
Amstad, P.3
Darzynkiewicz, Z.4
-
19
-
-
0035340652
-
Detection of caspases activation by fluorochrome-labeled inhibitors: Multiparameter analysis by laser scanning cytometry
-
Smolewski, P. et al. Detection of caspases activation by fluorochrome-labeled inhibitors: multiparameter analysis by laser scanning cytometry. Cytometry 44, 73-82 (2001).
-
(2001)
Cytometry
, vol.44
, pp. 73-82
-
-
Smolewski, P.1
-
20
-
-
3142616523
-
A caspase active site probe reveals high fractional inhibition needed to block DNA fragmentation
-
Méthot, N. et al. A caspase active site probe reveals high fractional inhibition needed to block DNA fragmentation. J. Biol. Chem. 279, 27905-27914 (2004).
-
(2004)
J. Biol. Chem
, vol.279
, pp. 27905-27914
-
-
Méthot, N.1
-
21
-
-
0242526431
-
Interactions of fluorochrome-labeled caspase inhibitors with apoptotic cells: A caution in data interpretation
-
Pozarowski, P. et al. Interactions of fluorochrome-labeled caspase inhibitors with apoptotic cells: a caution in data interpretation. Cytometry A 55, 50-60 (2003).
-
(2003)
Cytometry A
, vol.55
, pp. 50-60
-
-
Pozarowski, P.1
-
22
-
-
12444315984
-
Inhibition of papain-like cysteine proteases and legumain by caspase-specific inhibitors: When reaction mechanism is more important than specificity
-
Rozman-Pungerčar, J. et al. Inhibition of papain-like cysteine proteases and legumain by caspase-specific inhibitors: when reaction mechanism is more important than specificity. Cell Death Differ. 10, 881-888 (2003).
-
(2003)
Cell Death Differ
, vol.10
, pp. 881-888
-
-
Rozman-Pungerčar, J.1
-
23
-
-
33746972404
-
Identification of early intermediates of caspase activation using selective inhibitors and activity-based probes
-
Berger, A.B. et al. Identification of early intermediates of caspase activation using selective inhibitors and activity-based probes. Mol. Cell 23, 509-521 (2006).
-
(2006)
Mol. Cell
, vol.23
, pp. 509-521
-
-
Berger, A.B.1
-
24
-
-
0033180211
-
Reversible tumorigenesis by MYC in hematopoietic lineages
-
Felsher, D.W. & Bishop, J.M. Reversible tumorigenesis by MYC in hematopoietic lineages. Mol. Cell 4, 199-207 (1999).
-
(1999)
Mol. Cell
, vol.4
, pp. 199-207
-
-
Felsher, D.W.1
Bishop, J.M.2
-
25
-
-
17644386231
-
Cellular uptake of unconjugated TAT peptide involves clathrin-dependent endocytosis and heparan sulfate receptors
-
Richard, J.P. et al. Cellular uptake of unconjugated TAT peptide involves clathrin-dependent endocytosis and heparan sulfate receptors. J. Biol. Chem. 280, 15300-15306 (2005).
-
(2005)
J. Biol. Chem
, vol.280
, pp. 15300-15306
-
-
Richard, J.P.1
-
26
-
-
0027015928
-
Glucocorticoid-induced apoptosis in the thymus
-
Cohen, J.J. Glucocorticoid-induced apoptosis in the thymus. Semin. Immunol. 4, 363-369 (1992).
-
(1992)
Semin. Immunol
, vol.4
, pp. 363-369
-
-
Cohen, J.J.1
-
27
-
-
0036162988
-
Macrophages are involved in DNA degradation of apoptotic cells in murine thymus after administration of hydrocortisone
-
Odaka, C. & Mizuochi, T. Macrophages are involved in DNA degradation of apoptotic cells in murine thymus after administration of hydrocortisone. Cell Death Differ. 9, 104-112 (2002).
-
(2002)
Cell Death Differ
, vol.9
, pp. 104-112
-
-
Odaka, C.1
Mizuochi, T.2
-
28
-
-
0037103223
-
Thymocyte apoptosis induced by T cell activation is mediated by glucocorticoids in vivo
-
Brewer, J.A., Kanagawa, O., Sleckman, B.P. & Muglia, L.J. Thymocyte apoptosis induced by T cell activation is mediated by glucocorticoids in vivo. J. Immunol. 169, 1837-1843 (2002).
-
(2002)
J. Immunol
, vol.169
, pp. 1837-1843
-
-
Brewer, J.A.1
Kanagawa, O.2
Sleckman, B.P.3
Muglia, L.J.4
-
29
-
-
34547111256
-
123l]annexin V and in situ oligonucleotide ligation
-
123l]annexin V and in situ oligonucleotide ligation. J. Mol. Histol. 38, 313-319 (2007).
-
(2007)
J. Mol. Histol
, vol.38
, pp. 313-319
-
-
Zavitsanou, K.1
-
30
-
-
40949138762
-
Structural and functional analysis of the interaction between the agonistic monoclonal antibody Apomab and the proapoptotic receptor DR5
-
Adams, C. et al. Structural and functional analysis of the interaction between the agonistic monoclonal antibody Apomab and the proapoptotic receptor DR5. Cell Death Differ. 15, 751-761 (2008).
-
(2008)
Cell Death Differ
, vol.15
, pp. 751-761
-
-
Adams, C.1
-
31
-
-
44749085513
-
Targeting the extrinsic apoptosis pathway in cancer
-
Ashkenazi, A. Targeting the extrinsic apoptosis pathway in cancer. Cytokine Growth Factor Rev. 19, 325-331 (2008).
-
(2008)
Cytokine Growth Factor Rev
, vol.19
, pp. 325-331
-
-
Ashkenazi, A.1
-
32
-
-
0030904245
-
A truncated HIV-1 Tat protein basic domain rapidly translocates through the plasma membrane and accumulates in the cell nucleus
-
Vivès, E., Brodin, P. & Lebleu, B. A truncated HIV-1 Tat protein basic domain rapidly translocates through the plasma membrane and accumulates in the cell nucleus. J. Biol. Chem. 272, 16010-16017 (1997).
-
(1997)
J. Biol. Chem
, vol.272
, pp. 16010-16017
-
-
Vivès, E.1
Brodin, P.2
Lebleu, B.3
-
33
-
-
33947395719
-
Specificity of aza-peptide electrophile activity-based probes of caspases
-
Sexton, K.B. et al. Specificity of aza-peptide electrophile activity-based probes of caspases. Cell Death Differ. 14, 727-732 (2007).
-
(2007)
Cell Death Differ
, vol.14
, pp. 727-732
-
-
Sexton, K.B.1
-
34
-
-
0035891721
-
Parallel solution-phase synthesis of mechanism-based cysteine protease inhibitors
-
Lee, A. & Ellman, J.A. Parallel solution-phase synthesis of mechanism-based cysteine protease inhibitors. Org. Lett. 3, 3707-3709 (2001).
-
(2001)
Org. Lett
, vol.3
, pp. 3707-3709
-
-
Lee, A.1
Ellman, J.A.2
-
35
-
-
34548666006
-
Noninvasive optical imaging of cysteine protease activity using fluorescently quenched activity-based probes
-
Blum, G., von Degenfeld, G., Merchant, M.J., Blau, H.M. & Bogyo, M. Noninvasive optical imaging of cysteine protease activity using fluorescently quenched activity-based probes. Nat. Chem. Biol. 3, 668-677 (2007).
-
(2007)
Nat. Chem. Biol
, vol.3
, pp. 668-677
-
-
Blum, G.1
von Degenfeld, G.2
Merchant, M.J.3
Blau, H.M.4
Bogyo, M.5
|